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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for jund_batf

Z-value: 0.88

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Transcription factors associated with jund_batf

Gene Symbol Gene ID Gene Info
jund
ENSDARG00000067850 JunD proto-oncogene, AP-1 transcription factor subunit
batf
ENSDARG00000011818 basic leucine zipper transcription factor, ATF-like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
junddr11_v1_chr2_-_56131312_56131312-0.447.3e-06Click!
batfdr11_v1_chr20_+_46572550_46572550-0.038.1e-01Click!

Activity profile of jund_batf motif

Sorted Z-values of jund_batf motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_56176976 21.28 ENSDART00000052688
c3a.1
complement component c3a, duplicate 1
chr13_-_20381485 18.11 ENSDART00000131351
si:ch211-270n8.1
si:ch211-270n8.1
chr7_+_25036188 15.17 ENSDART00000163957
ENSDART00000169749
sb:cb1058
sb:cb1058
chr10_+_28428222 11.43 ENSDART00000135003
si:ch211-222e20.4
si:ch211-222e20.4
chr1_+_135903 10.48 ENSDART00000124837
f10
coagulation factor X
chr3_-_26017592 8.94 ENSDART00000030890
hmox1a
heme oxygenase 1a
chr8_-_38201415 8.29 ENSDART00000155189
pdlim2
PDZ and LIM domain 2 (mystique)
chr3_-_26017831 7.70 ENSDART00000179982
hmox1a
heme oxygenase 1a
chr16_-_13818061 6.97 ENSDART00000132982
ENSDART00000144856
leng9
leukocyte receptor cluster (LRC) member 9
chr15_-_21877726 6.37 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr1_+_14253118 6.19 ENSDART00000161996
cxcl8a
chemokine (C-X-C motif) ligand 8a
chr4_+_1530287 5.48 ENSDART00000067446
slc38a4
solute carrier family 38, member 4
chr16_-_24832038 5.46 ENSDART00000153731
si:dkey-79d12.5
si:dkey-79d12.5
chr14_+_30774515 5.26 ENSDART00000191666
atl3
atlastin 3
chr25_+_10410620 5.05 ENSDART00000151886
ehf
ets homologous factor
chr22_+_38173960 5.05 ENSDART00000010537
cp
ceruloplasmin
chr14_+_30774032 4.97 ENSDART00000139552
atl3
atlastin 3
chr25_+_18583877 4.89 ENSDART00000148741
met
MET proto-oncogene, receptor tyrosine kinase
chr5_+_66170479 4.77 ENSDART00000172117
gldc
glycine dehydrogenase (decarboxylating)
chr19_-_5669122 4.68 ENSDART00000112211
si:ch211-264f5.2
si:ch211-264f5.2
chr20_+_34868933 4.53 ENSDART00000153006
ankef1a
ankyrin repeat and EF-hand domain containing 1a
chr11_-_2478374 4.14 ENSDART00000173205
si:ch73-267c23.10
si:ch73-267c23.10
chr20_-_33704753 4.07 ENSDART00000157427
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr5_-_41531629 3.99 ENSDART00000051082
akr1a1a
aldo-keto reductase family 1, member A1a (aldehyde reductase)
chr1_-_58913813 3.86 ENSDART00000056494
zgc:171687
zgc:171687
chr23_-_4975452 3.82 ENSDART00000105241
ENSDART00000169978
ngfa
nerve growth factor a (beta polypeptide)
chr15_-_31357634 3.80 ENSDART00000127485
or111-2
odorant receptor, family D, subfamily 111, member 2
chr4_+_42175261 3.70 ENSDART00000162193
si:ch211-142b24.2
si:ch211-142b24.2
chr6_-_43449013 3.65 ENSDART00000122423
eevs
2-epi-5-epi-valiolone synthase
chr3_+_16976095 3.55 ENSDART00000112450
cavin1a
caveolae associated protein 1a
chr14_+_30774894 3.54 ENSDART00000023054
atl3
atlastin 3
chr9_+_38644976 3.46 ENSDART00000133849
ENSDART00000135774
slc12a8
solute carrier family 12, member 8
chr4_-_13518381 3.45 ENSDART00000067153
ifng1-1
interferon, gamma 1-1
chr13_+_24280380 3.43 ENSDART00000184115
acta1b
actin, alpha 1b, skeletal muscle
chr20_+_572037 3.37 ENSDART00000028062
ENSDART00000152736
ENSDART00000031759
ENSDART00000162198
smyd2b
SET and MYND domain containing 2b
chr23_+_30967686 3.34 ENSDART00000144485
si:ch211-197l9.2
si:ch211-197l9.2
chr25_+_29474982 3.28 ENSDART00000130410
il17rel
interleukin 17 receptor E-like
chr3_-_16289826 3.24 ENSDART00000131972
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr22_-_26595027 3.22 ENSDART00000184162
CABZ01072309.1

chr22_+_19405517 3.21 ENSDART00000138245
ENSDART00000155144
si:dkey-78l4.2
si:dkey-78l4.2
chr1_+_59088205 3.16 ENSDART00000150649
ENSDART00000100197
zgc:173915
zgc:173915
chr16_+_18974064 3.12 ENSDART00000079248
slc6a19b
solute carrier family 6 (neutral amino acid transporter), member 19b
chr6_-_31224563 3.08 ENSDART00000104616
lepr
leptin receptor
chr20_-_2134620 3.07 ENSDART00000064375
tmem244
transmembrane protein 244
chr22_+_19218733 3.03 ENSDART00000183212
ENSDART00000133595
si:dkey-21e2.7
si:dkey-21e2.7
chr24_+_13277573 2.97 ENSDART00000137886
si:ch211-171b20.3
si:ch211-171b20.3
chr24_+_35827766 2.96 ENSDART00000144700
si:dkeyp-7a3.1
si:dkeyp-7a3.1
chr7_-_13906409 2.95 ENSDART00000062257
slc39a1
solute carrier family 39 (zinc transporter), member 1
chr16_-_25608453 2.94 ENSDART00000140140
zgc:110410
zgc:110410
chr6_+_598669 2.87 ENSDART00000151009
si:ch73-379f7.4
si:ch73-379f7.4
chr22_+_16497670 2.84 ENSDART00000014330
ier5
immediate early response 5
chr9_+_38645136 2.83 ENSDART00000135505
slc12a8
solute carrier family 12, member 8
chr8_+_50531709 2.81 ENSDART00000193352
PEBP4
phosphatidylethanolamine binding protein 4
chr19_+_37118547 2.80 ENSDART00000103163
cx30.9
connexin 30.9
chr13_+_35637875 2.77 ENSDART00000180657
thbs2a
thrombospondin 2a
chr9_+_14010823 2.76 ENSDART00000143837
si:ch211-67e16.3
si:ch211-67e16.3
chr22_+_19247255 2.74 ENSDART00000144053
si:dkey-21e2.10
si:dkey-21e2.10
chr1_+_57724157 2.64 ENSDART00000181754
si:dkey-1c7.1
si:dkey-1c7.1
chr19_+_42142381 2.63 ENSDART00000129915
kcnq4
potassium voltage-gated channel, KQT-like subfamily, member 4
chr22_+_28337204 2.44 ENSDART00000163352
impg2b
interphotoreceptor matrix proteoglycan 2b
chr16_+_16824678 2.43 ENSDART00000172862
kcnj14
potassium inwardly-rectifying channel, subfamily J, member 14
chr22_+_19365220 2.42 ENSDART00000132781
ENSDART00000135672
ENSDART00000153630
si:dkey-21e2.12
si:dkey-21e2.12
chr10_-_40514643 2.27 ENSDART00000140705
taar19k
trace amine associated receptor 19k
chr21_+_25765734 2.22 ENSDART00000021664
cldnb
claudin b
chr18_-_46010 2.13 ENSDART00000052641
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr15_+_15771418 2.13 ENSDART00000153831
si:ch211-33e4.3
si:ch211-33e4.3
chr22_-_817479 2.11 ENSDART00000123487
zgc:153675
zgc:153675
chr7_+_29509255 2.09 ENSDART00000076172
si:dkey-182o15.5
si:dkey-182o15.5
chr5_+_26799165 2.05 ENSDART00000145736
tcn2
transcobalamin II
chr8_+_8973425 2.04 ENSDART00000066107
bcap31
B cell receptor associated protein 31
chr20_+_2134816 2.01 ENSDART00000039249
l3mbtl3
l(3)mbt-like 3 (Drosophila)
chr22_+_36914636 2.00 ENSDART00000150948
pimr205
Pim proto-oncogene, serine/threonine kinase, related 205
chr20_+_25340814 2.00 ENSDART00000063028
ctgfa
connective tissue growth factor a
chr5_+_50953240 1.96 ENSDART00000148501
ENSDART00000149892
ENSDART00000190312
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr23_+_19655301 1.95 ENSDART00000104441
ENSDART00000135269
abhd6b
abhydrolase domain containing 6b
chr10_-_40479911 1.92 ENSDART00000136741
taar20d1
trace amine associated receptor 20d1
chr16_-_5105295 1.90 ENSDART00000082071
ENSDART00000148955
ENSDART00000184700
ENSDART00000188127
bckdhb
branched chain keto acid dehydrogenase E1, beta polypeptide
chr14_+_3507326 1.90 ENSDART00000159326
gstp1
glutathione S-transferase pi 1
chr16_+_46410520 1.86 ENSDART00000131072
rpz2
rapunzel 2
chr6_+_49095646 1.85 ENSDART00000103385
slc25a55a
solute carrier family 25, member 55a
chr16_+_19029297 1.82 ENSDART00000115263
ENSDART00000114954
rapgef5b
Rap guanine nucleotide exchange factor (GEF) 5b
chr3_-_4760384 1.81 ENSDART00000108810
CABZ01046997.1

chr7_+_55149001 1.81 ENSDART00000148642
cdh31
cadherin 31
chr19_+_10527228 1.80 ENSDART00000091918
si:ch73-160i9.3
si:ch73-160i9.3
chr25_-_19666107 1.78 ENSDART00000149889
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr18_-_15771551 1.77 ENSDART00000130931
ENSDART00000154079
si:ch211-219a15.3
si:ch211-219a15.3
chr21_-_2415808 1.76 ENSDART00000171179
si:ch211-241b2.5
si:ch211-241b2.5
chr3_+_31621774 1.71 ENSDART00000076636
fzd2
frizzled class receptor 2
chr22_+_19266995 1.71 ENSDART00000133995
ENSDART00000144963
si:dkey-21e2.12
si:dkey-21e2.12
chr1_-_43897831 1.70 ENSDART00000048225
si:dkey-22i16.2
si:dkey-22i16.2
chr13_-_9335891 1.70 ENSDART00000080637
BX901922.1

chr8_-_52745141 1.67 ENSDART00000168359
ENSDART00000168252
fgf17
fibroblast growth factor 17
chr5_+_23994038 1.65 ENSDART00000186175
AL928875.1

chr12_+_48390715 1.62 ENSDART00000149351
scd
stearoyl-CoA desaturase (delta-9-desaturase)
chr14_-_32884138 1.61 ENSDART00000105726
slc25a5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr2_-_24069331 1.59 ENSDART00000156972
ENSDART00000181691
ENSDART00000157041
slc12a7a
solute carrier family 12 (potassium/chloride transporter), member 7a
chr13_-_42749916 1.59 ENSDART00000140019
capn2a
calpain 2, (m/II) large subunit a
chr12_+_16132612 1.59 ENSDART00000152550
lrp2b
low density lipoprotein receptor-related protein 2b
chr12_+_46634736 1.58 ENSDART00000008009
trim16
tripartite motif containing 16
chr3_-_34070451 1.54 ENSDART00000151458
ighv8-3
immunoglobulin heavy variable 8-3
chr6_-_43028896 1.53 ENSDART00000149977
glyctk
glycerate kinase
chr25_+_29474583 1.50 ENSDART00000191189
il17rel
interleukin 17 receptor E-like
chr19_-_27395531 1.49 ENSDART00000103940
mgat1b
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase b
chr12_+_46740584 1.47 ENSDART00000171563
plaub
plasminogen activator, urokinase b
chr9_-_1978090 1.47 ENSDART00000082344
hoxd11a
homeobox D11a
chr20_+_37393134 1.47 ENSDART00000128321
adgrg6
adhesion G protein-coupled receptor G6
chr12_-_25294096 1.46 ENSDART00000183398
hcar1-4
hydroxycarboxylic acid receptor 1-4
chr21_+_33459524 1.46 ENSDART00000053205
cd74b
CD74 molecule, major histocompatibility complex, class II invariant chain b
chr8_-_7603700 1.43 ENSDART00000137975
irak1
interleukin-1 receptor-associated kinase 1
chr12_+_41348969 1.39 ENSDART00000171352
si:ch211-27e6.1
si:ch211-27e6.1
chr13_-_12602920 1.39 ENSDART00000102311
lrit3b
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr11_+_45219558 1.39 ENSDART00000167828
tmc6b
transmembrane channel-like 6b
chr25_-_29072162 1.38 ENSDART00000169269
arid3b
AT rich interactive domain 3B (BRIGHT-like)
chr14_+_10461264 1.38 ENSDART00000081095
cysltr1
cysteinyl leukotriene receptor 1
chr1_+_57761632 1.36 ENSDART00000112472
si:dkey-1c7.1
si:dkey-1c7.1
chr2_-_6232517 1.35 ENSDART00000139842
rec8a
REC8 meiotic recombination protein a
chr2_+_25378457 1.33 ENSDART00000089108
fndc3ba
fibronectin type III domain containing 3Ba
chr6_+_56141852 1.32 ENSDART00000149665
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr11_-_39202915 1.31 ENSDART00000105133
wnt4a
wingless-type MMTV integration site family, member 4a
chr17_-_52091999 1.29 ENSDART00000019766
tgfb3
transforming growth factor, beta 3
chr15_+_17722054 1.28 ENSDART00000191390
ENSDART00000169550
si:ch211-213d14.1
si:ch211-213d14.1
chr5_+_42141917 1.28 ENSDART00000172201
ENSDART00000140743
trpv1
transient receptor potential cation channel, subfamily V, member 1
chr13_+_8987957 1.26 ENSDART00000148144
hcar1-3
hydroxycarboxylic acid receptor 1-3
chr4_-_60780423 1.23 ENSDART00000162632
si:dkey-254e13.6
si:dkey-254e13.6
chr4_+_47436126 1.20 ENSDART00000157555
si:dkey-124l13.1
si:dkey-124l13.1
chr1_-_11606903 1.20 ENSDART00000136093
si:dkey-26i13.6
si:dkey-26i13.6
chr10_+_7718156 1.19 ENSDART00000189101
ggcx
gamma-glutamyl carboxylase
chr17_-_6536466 1.18 ENSDART00000188735
cenpo
centromere protein O
chr3_-_21402279 1.17 ENSDART00000164513
CT573446.1

chr7_-_60351876 1.14 ENSDART00000098563
plcb3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr7_+_34786591 1.13 ENSDART00000173700
si:dkey-148a17.5
si:dkey-148a17.5
chr23_-_44848961 1.13 ENSDART00000136839
wu:fb72h05
wu:fb72h05
chr24_+_31361407 1.12 ENSDART00000162668
cremb
cAMP responsive element modulator b
chr1_-_47122058 1.09 ENSDART00000159925
ENSDART00000101143
ENSDART00000176803
mhc1zea
major histocompatibility complex class I ZEA
chr18_+_9362455 1.09 ENSDART00000187025
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr8_+_13389115 1.07 ENSDART00000184428
ENSDART00000154266
ENSDART00000049469
jak3
Janus kinase 3 (a protein tyrosine kinase, leukocyte)
chr4_-_50930346 1.06 ENSDART00000184245
si:ch211-208f21.3
si:ch211-208f21.3
chr25_-_15504559 1.06 ENSDART00000139294
BX323543.5

chr15_-_29586747 1.06 ENSDART00000076749
samsn1a
SAM domain, SH3 domain and nuclear localisation signals 1a
chr25_-_15512819 1.05 ENSDART00000142684
si:dkeyp-67e1.2
si:dkeyp-67e1.2
chr10_+_40700311 1.05 ENSDART00000157650
ENSDART00000138342
taar19n
trace amine associated receptor 19n
chr4_-_76270779 1.04 ENSDART00000183709
ENSDART00000192689
si:ch211-106j21.4
si:ch211-106j21.4
chr4_-_36476889 1.03 ENSDART00000163956
si:ch211-263l8.1
si:ch211-263l8.1
chr17_-_23727978 1.03 ENSDART00000079600
minpp1a
multiple inositol-polyphosphate phosphatase 1a
chr1_+_57757456 1.02 ENSDART00000152650
si:dkey-1c7.1
si:dkey-1c7.1
chr8_-_36554675 1.02 ENSDART00000132804
ENSDART00000078746
ccdc157
coiled-coil domain containing 157
chr4_-_72476526 1.01 ENSDART00000174153
CR788316.1

chr23_-_1017428 1.01 ENSDART00000110588
ENSDART00000183158
cdh26.1
cadherin 26, tandem duplicate 1
chr20_-_34127415 1.00 ENSDART00000010028
ptgs2b
prostaglandin-endoperoxide synthase 2b
chr7_-_35408618 0.99 ENSDART00000074963
lpcat2
lysophosphatidylcholine acyltransferase 2
chr9_-_7640692 0.99 ENSDART00000135616
dnajb2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr25_-_35169303 0.98 ENSDART00000193240
ano9a
anoctamin 9a
chr8_+_25034544 0.97 ENSDART00000123300
ngrn
neugrin, neurite outgrowth associated
chr3_-_39488482 0.96 ENSDART00000135192
zgc:100868
zgc:100868
chr1_+_57741577 0.94 ENSDART00000192673
LO018597.1

chr2_-_6519017 0.93 ENSDART00000181716
rgs1
regulator of G protein signaling 1
chr14_-_34074510 0.93 ENSDART00000172753
itk
IL2 inducible T cell kinase
chr2_+_30379650 0.93 ENSDART00000129542
crispld1b
cysteine-rich secretory protein LCCL domain containing 1b
chr7_+_6317866 0.92 ENSDART00000173397
si:ch211-220f21.3
si:ch211-220f21.3
chr7_-_6357952 0.92 ENSDART00000173197
zgc:165555
zgc:165555
chr12_+_292452 0.91 ENSDART00000189944
CABZ01058222.1

chr3_+_58092212 0.91 ENSDART00000156059
si:ch211-256e16.7
si:ch211-256e16.7
chr21_+_5888641 0.90 ENSDART00000091331
prodha
proline dehydrogenase (oxidase) 1a
chr4_+_34121902 0.90 ENSDART00000170225
si:ch211-223g7.6
si:ch211-223g7.6
chr5_-_54772982 0.90 ENSDART00000122829
pik3r1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_+_54645654 0.90 ENSDART00000192864
si:ch211-227e10.1
si:ch211-227e10.1
chr3_-_39488639 0.90 ENSDART00000161644
zgc:100868
zgc:100868
chr24_+_26658132 0.90 ENSDART00000183081
FQ378040.1

chr5_+_54585431 0.90 ENSDART00000171225
npr2
natriuretic peptide receptor 2
chr5_-_30984010 0.87 ENSDART00000182367
spns3
spinster homolog 3 (Drosophila)
chr13_+_35339182 0.86 ENSDART00000019323
jag1b
jagged 1b
chr4_-_39265279 0.86 ENSDART00000164912
si:ch73-236c18.2
si:ch73-236c18.2
chr11_+_21050326 0.85 ENSDART00000065984
zgc:113307
zgc:113307
chr8_-_44463985 0.85 ENSDART00000016845
mhc1lba
major histocompatibility complex class I LBA
chr23_-_1017605 0.85 ENSDART00000138290
cdh26.1
cadherin 26, tandem duplicate 1
chr19_+_40856807 0.85 ENSDART00000139083
gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr21_+_10790680 0.84 ENSDART00000144460
znf532
zinc finger protein 532
chr9_-_19699728 0.84 ENSDART00000166780
si:ch211-141e20.2
si:ch211-141e20.2
chr4_-_17793152 0.84 ENSDART00000134080
mybpc1
myosin binding protein C, slow type
chr14_+_22132896 0.83 ENSDART00000138274
ccng1
cyclin G1
chr19_+_26072624 0.83 ENSDART00000147627
jarid2b
jumonji, AT rich interactive domain 2b
chr18_-_7677208 0.83 ENSDART00000092456
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr8_-_3413139 0.82 ENSDART00000182673
ENSDART00000166741
ENSDART00000169430
ENSDART00000170478
FUT9 (1 of many)
FUT9 (1 of many)
fut9b
zgc:103510
zgc:165519
fucosyltransferase 9b
chr14_-_22100118 0.82 ENSDART00000157547
ssrp1a
structure specific recognition protein 1a
chr24_+_7800486 0.81 ENSDART00000145504
ptprh
protein tyrosine phosphatase, receptor type, h
chr2_-_49997055 0.79 ENSDART00000140294
si:ch211-106n13.3
si:ch211-106n13.3
chr10_+_31248036 0.79 ENSDART00000193574
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr17_-_6536305 0.78 ENSDART00000154855
cenpo
centromere protein O
chr16_+_12660477 0.77 ENSDART00000016834
aicda
activation-induced cytidine deaminase
chr4_-_75899294 0.77 ENSDART00000157887
si:dkey-261j11.3
si:dkey-261j11.3
chr23_-_36753195 0.76 ENSDART00000181104
CU571398.1

chr24_-_38192003 0.75 ENSDART00000109975
crp7
C-reactive protein 7
chr5_+_63767376 0.74 ENSDART00000138898
rgs3b
regulator of G protein signaling 3b
chr13_-_5257303 0.74 ENSDART00000110610
si:dkey-78p8.1
si:dkey-78p8.1
chr10_+_31953502 0.73 ENSDART00000185634
lhfpl6
LHFPL tetraspan subfamily member 6
chr1_+_57752724 0.73 ENSDART00000169976
si:dkey-1c7.1
si:dkey-1c7.1
chr25_-_11026907 0.72 ENSDART00000156846
mespbb
mesoderm posterior bb
chr5_+_24089334 0.71 ENSDART00000183748
tp53
tumor protein p53
chr4_+_51564997 0.71 ENSDART00000186119
si:dkey-165e24.1
si:dkey-165e24.1
chr5_+_61556172 0.70 ENSDART00000131937
orai2
ORAI calcium release-activated calcium modulator 2

Network of associatons between targets according to the STRING database.

First level regulatory network of jund_batf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.6 GO:0043576 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
2.1 6.2 GO:0002631 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
1.3 6.4 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
1.2 4.8 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.7 2.1 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.7 2.0 GO:0015889 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.6 1.7 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.5 1.5 GO:0060879 peripheral nervous system myelin formation(GO:0032290) semicircular canal fusion(GO:0060879)
0.5 1.5 GO:0060907 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.5 0.5 GO:0061045 negative regulation of wound healing(GO:0061045)
0.4 4.9 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.4 3.6 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.4 7.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.4 3.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.4 2.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.4 1.6 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.4 1.6 GO:0015859 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.4 1.1 GO:0001779 natural killer cell differentiation(GO:0001779)
0.3 3.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 0.8 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 22.8 GO:0006956 complement activation(GO:0006956)
0.3 13.8 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.3 0.8 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.3 1.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 6.7 GO:0006884 cell volume homeostasis(GO:0006884)
0.2 5.0 GO:0006825 copper ion transport(GO:0006825)
0.2 0.7 GO:0010526 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.2 4.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.2 1.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 4.1 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.2 0.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 1.9 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.2 1.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.2 0.9 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 1.8 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.2 1.9 GO:0007584 response to nutrient(GO:0007584)
0.2 1.4 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.2 0.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 3.1 GO:0009749 response to glucose(GO:0009749)
0.2 1.7 GO:0042664 negative regulation of endodermal cell fate specification(GO:0042664)
0.1 0.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.6 GO:0016038 absorption of visible light(GO:0016038)
0.1 3.0 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 1.7 GO:0045144 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
0.1 1.5 GO:0031639 plasminogen activation(GO:0031639)
0.1 10.5 GO:0007596 blood coagulation(GO:0007596)
0.1 1.0 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.1 0.7 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.8 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.3 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.1 1.3 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 0.2 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.1 1.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.4 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.6 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.6 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.1 0.9 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 1.1 GO:0090279 regulation of calcium ion import(GO:0090279)
0.1 0.6 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 2.8 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 5.5 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.1 0.4 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 1.3 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.3 GO:0039703 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.1 0.9 GO:0060325 face morphogenesis(GO:0060325)
0.1 5.0 GO:0050673 epithelial cell proliferation(GO:0050673)
0.1 0.5 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.7 GO:0048899 anterior lateral line development(GO:0048899)
0.1 4.3 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.9 GO:0060038 striated muscle cell proliferation(GO:0014855) cardiac muscle cell proliferation(GO:0060038)
0.0 2.2 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 1.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.6 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 2.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.7 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.4 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.6 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 2.2 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.5 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 1.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0044706 parturition(GO:0007567) neurohypophysis development(GO:0021985) multi-multicellular organism process(GO:0044706) maternal process involved in parturition(GO:0060137)
0.0 0.6 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 3.3 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 8.3 GO:0061061 muscle structure development(GO:0061061)
0.0 0.8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.9 GO:0051693 actin filament capping(GO:0051693)
0.0 0.3 GO:0019835 cytolysis(GO:0019835)
0.0 1.5 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.2 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.6 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 1.6 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.8 GO:1902275 regulation of chromatin organization(GO:1902275)
0.0 1.6 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 2.4 GO:0007601 visual perception(GO:0007601)
0.0 1.4 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 2.6 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.0 0.7 GO:0005977 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 3.7 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0006446 regulation of translational initiation(GO:0006446)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0005960 glycine cleavage complex(GO:0005960)
0.6 1.9 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.5 2.0 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.5 6.4 GO:0042627 chylomicron(GO:0042627)
0.5 2.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.2 4.9 GO:0009925 basal plasma membrane(GO:0009925)
0.2 3.4 GO:0005869 dynactin complex(GO:0005869)
0.2 1.4 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.2 8.9 GO:0031941 filamentous actin(GO:0031941)
0.2 1.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.7 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 4.1 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 1.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.8 GO:0035101 FACT complex(GO:0035101)
0.1 0.4 GO:0000811 GINS complex(GO:0000811)
0.1 3.7 GO:0016342 catenin complex(GO:0016342)
0.1 0.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 5.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.8 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 62.7 GO:0005615 extracellular space(GO:0005615)
0.0 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.0 2.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 5.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.2 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.7 GO:0043596 nuclear replication fork(GO:0043596)
0.0 1.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 2.2 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 5.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.8 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 16.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
1.5 6.2 GO:0005153 interleukin-8 receptor binding(GO:0005153)
1.3 6.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.9 3.6 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.8 4.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.5 4.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.4 4.8 GO:0016594 glycine binding(GO:0016594)
0.4 8.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.4 1.6 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.4 3.6 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.4 1.6 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.4 4.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.4 1.5 GO:0008887 glycerate kinase activity(GO:0008887)
0.4 1.5 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.3 5.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 1.6 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.3 1.2 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.3 3.8 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.3 6.7 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.3 1.0 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.3 2.0 GO:0031419 cobalamin binding(GO:0031419)
0.3 1.0 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 0.9 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.2 1.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 3.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 1.7 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 1.4 GO:0004974 leukotriene receptor activity(GO:0004974)
0.2 0.6 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 3.2 GO:0033691 sialic acid binding(GO:0033691)
0.2 0.5 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.2 4.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 1.9 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.1 8.6 GO:0003823 antigen binding(GO:0003823)
0.1 21.2 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 0.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.9 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.9 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.8 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.5 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 1.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 24.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 3.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 1.8 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.8 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 1.1 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.5 GO:0043236 laminin binding(GO:0043236)
0.1 2.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.1 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 2.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 1.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 1.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.0 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 4.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.6 GO:0042562 hormone binding(GO:0042562)
0.1 2.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.6 GO:0051117 ATPase binding(GO:0051117)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 3.7 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0004990 oxytocin receptor activity(GO:0004990)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.4 GO:0030507 spectrin binding(GO:0030507)
0.0 0.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 3.3 GO:0019955 cytokine binding(GO:0019955)
0.0 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 12.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.8 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 3.1 GO:0015293 symporter activity(GO:0015293)
0.0 2.2 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.1 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 2.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.3 GO:0005262 calcium channel activity(GO:0005262)
0.0 2.4 GO:0042393 histone binding(GO:0042393)
0.0 11.4 GO:0004888 transmembrane signaling receptor activity(GO:0004888)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 1.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.2 4.9 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 4.0 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 1.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.7 PID FGF PATHWAY FGF signaling pathway
0.1 1.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.9 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 11.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4 8.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.3 1.7 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.2 4.9 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.2 5.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 0.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 2.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 1.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 1.4 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 1.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.6 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.1 1.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.6 REACTOME OPSINS Genes involved in Opsins
0.1 2.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 0.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 2.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.6 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis