Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for lhx1a+lhx1b

Z-value: 0.40

Motif logo

logo of

Transcription factors associated with lhx1a+lhx1b

Gene Symbol Gene ID Gene Info
lhx1b
ENSDARG00000007944 LIM homeobox 1b
lhx1a
ENSDARG00000014018 LIM homeobox 1a
lhx1b
ENSDARG00000111635 LIM homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lhx1bdr11_v1_chr5_+_56268436_562684360.214.5e-02Click!
lhx1adr11_v1_chr15_-_27710513_277105750.161.2e-01Click!

Activity profile of lhx1a+lhx1b motif

Sorted Z-values of lhx1a+lhx1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_32818607 5.47 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr9_+_34641237 3.39 ENSDART00000133996
shox
short stature homeobox
chr24_-_26328721 3.38 ENSDART00000125468
apodb
apolipoprotein Db
chr4_+_9669717 2.44 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr25_+_4751879 2.42 ENSDART00000169465
si:zfos-2372e4.1
si:zfos-2372e4.1
chr24_+_2495197 2.24 ENSDART00000146887
f13a1a.1
coagulation factor XIII, A1 polypeptide a, tandem duplicate 1
chr6_-_30839763 2.21 ENSDART00000154228
sgip1a
SH3-domain GRB2-like (endophilin) interacting protein 1a
chr5_+_4054704 2.17 ENSDART00000140537
dhrs11a
dehydrogenase/reductase (SDR family) member 11a
chr3_-_19368435 1.94 ENSDART00000132987
s1pr5a
sphingosine-1-phosphate receptor 5a
chr7_-_38658411 1.84 ENSDART00000109463
ENSDART00000017155
npsn
nephrosin
chr19_+_2631565 1.70 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr18_-_17485419 1.66 ENSDART00000018764
foxl1
forkhead box L1
chr23_+_4689626 1.55 ENSDART00000131532
gp9
glycoprotein IX (platelet)
chr6_-_40029423 1.55 ENSDART00000103230
pfkfb4b
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b
chr15_-_43284021 1.50 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr10_-_11261565 1.41 ENSDART00000146727
ptbp3
polypyrimidine tract binding protein 3
chr5_+_60590796 1.38 ENSDART00000159859
tmem132e
transmembrane protein 132E
chr12_-_17712393 1.37 ENSDART00000143534
ENSDART00000010144
pvalb2
parvalbumin 2
chr21_-_35419486 1.31 ENSDART00000138529
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr1_+_6172786 1.27 ENSDART00000126468
prkag3a
protein kinase, AMP-activated, gamma 3a non-catalytic subunit
chr9_-_9415000 1.26 ENSDART00000146210
si:ch211-214p13.9
si:ch211-214p13.9
chr17_-_16422654 1.23 ENSDART00000150149
tdp1
tyrosyl-DNA phosphodiesterase 1
chr17_-_45040813 1.18 ENSDART00000075514
entpd5a
ectonucleoside triphosphate diphosphohydrolase 5a
chr20_-_45812144 1.18 ENSDART00000147897
ENSDART00000147637
fermt1
fermitin family member 1
chr2_+_20605925 1.11 ENSDART00000191510
olfml2bb
olfactomedin-like 2Bb
chr16_-_28856112 1.07 ENSDART00000078543
syt11b
synaptotagmin XIb
chr5_+_61301525 1.03 ENSDART00000128773
doc2b
double C2-like domains, beta
chr3_+_39853788 1.03 ENSDART00000154869
cacna1ha
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr21_-_20939488 1.02 ENSDART00000039043
rgs7bpb
regulator of G protein signaling 7 binding protein b
chr19_+_46158078 0.98 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr9_+_24159280 0.98 ENSDART00000184624
ENSDART00000178422
hecw2a
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a
chr3_-_15999501 0.97 ENSDART00000160668
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr6_-_50730749 0.96 ENSDART00000157153
ENSDART00000110441
pigu
phosphatidylinositol glycan anchor biosynthesis, class U
chr6_-_11768198 0.93 ENSDART00000183463
march7
membrane-associated ring finger (C3HC4) 7
chr1_+_10318089 0.90 ENSDART00000029774
pip4p1b
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr11_-_40204621 0.88 ENSDART00000086287
znf362a
zinc finger protein 362a
chr24_-_35767501 0.88 ENSDART00000105680
ENSDART00000042290
ENSDART00000166264
dtna
dystrobrevin, alpha
chr19_+_43297546 0.86 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr19_-_5769728 0.83 ENSDART00000133106
si:ch211-264f5.6
si:ch211-264f5.6
chr6_+_7444899 0.82 ENSDART00000053775
arf3b
ADP-ribosylation factor 3b
chr4_+_16885854 0.78 ENSDART00000017726
etnk1
ethanolamine kinase 1
chr2_-_16217344 0.76 ENSDART00000152031
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr12_+_7497882 0.76 ENSDART00000134608
phyhiplb
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr16_+_2820340 0.75 ENSDART00000092299
ENSDART00000192931
ENSDART00000148512
si:dkey-288i20.2
si:dkey-288i20.2
chr9_-_14504834 0.71 ENSDART00000056103
nrp2b
neuropilin 2b
chr9_-_47472998 0.70 ENSDART00000134480
tns1b
tensin 1b
chr19_-_5769553 0.69 ENSDART00000175003
si:ch211-264f5.6
si:ch211-264f5.6
chr16_+_54209504 0.69 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr22_-_28226948 0.68 ENSDART00000147686
si:dkey-222p3.1
si:dkey-222p3.1
chr15_-_20939579 0.66 ENSDART00000152371
usp2a
ubiquitin specific peptidase 2a
chr6_+_35052721 0.66 ENSDART00000191090
ENSDART00000082940
uhmk1
U2AF homology motif (UHM) kinase 1
chr13_-_29420885 0.65 ENSDART00000024225
chata
choline O-acetyltransferase a
chr12_+_45200744 0.64 ENSDART00000098932
wbp2
WW domain binding protein 2
chr6_-_44402358 0.62 ENSDART00000193007
ENSDART00000193603
pdzrn3b
PDZ domain containing RING finger 3b
chr3_-_26806032 0.62 ENSDART00000143710
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr1_-_51038885 0.61 ENSDART00000035150
spast
spastin
chr13_+_11440389 0.60 ENSDART00000186463
zbtb18
zinc finger and BTB domain containing 18
chr10_-_11261386 0.58 ENSDART00000189946
ptbp3
polypyrimidine tract binding protein 3
chr11_-_25733910 0.57 ENSDART00000171935
brpf3a
bromodomain and PHD finger containing, 3a
chr6_+_11989537 0.55 ENSDART00000190817
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr4_+_12966640 0.54 ENSDART00000113357
vhll
von Hippel-Lindau tumor suppressor like
chr17_+_45405821 0.54 ENSDART00000189482
ENSDART00000177422
tagapa
T cell activation RhoGTPase activating protein a
chr24_+_28953089 0.54 ENSDART00000153761
rnpc3
RNA-binding region (RNP1, RRM) containing 3
chr13_-_29421331 0.53 ENSDART00000150228
chata
choline O-acetyltransferase a
chr15_-_17618800 0.53 ENSDART00000157185
adamts15b
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr1_+_51039558 0.52 ENSDART00000024743
dpy30
dpy-30 histone methyltransferase complex regulatory subunit
chr1_-_669717 0.50 ENSDART00000160564
cyyr1
cysteine/tyrosine-rich 1
chr16_-_12173554 0.49 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr10_+_17235370 0.49 ENSDART00000038780
sppl3
signal peptide peptidase 3
chr3_-_56541723 0.49 ENSDART00000156398
ENSDART00000050576
ENSDART00000184874
si:ch211-189a21.1
cyth1a
si:ch211-189a21.1
cytohesin 1a
chr22_-_12160283 0.48 ENSDART00000146785
ENSDART00000128176
tmem163b
transmembrane protein 163b
chr22_-_8725768 0.48 ENSDART00000189873
ENSDART00000181819
si:ch73-27e22.1
si:ch73-27e22.8
si:ch73-27e22.1
si:ch73-27e22.8
chr25_-_25058508 0.48 ENSDART00000087570
ENSDART00000178891
FQ311928.1

chr7_-_17297156 0.48 ENSDART00000161336
nitr11a
novel immune-type receptor 11a
chr11_+_30663300 0.47 ENSDART00000161662
ttbk1a
tau tubulin kinase 1a
chr4_+_52212057 0.44 ENSDART00000165627
znf1034
zinc finger protein 1034
chr3_+_26342768 0.43 ENSDART00000163832
si:ch211-156b7.4
si:ch211-156b7.4
chr23_-_31969786 0.43 ENSDART00000134550
ormdl2
ORMDL sphingolipid biosynthesis regulator 2
chr10_+_45089820 0.43 ENSDART00000175481
camk2b2
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr21_-_2415808 0.42 ENSDART00000171179
si:ch211-241b2.5
si:ch211-241b2.5
chr22_-_10156581 0.39 ENSDART00000168304
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr25_+_18711804 0.39 ENSDART00000011149
fam185a
family with sequence similarity 185, member A
chr3_-_11624694 0.36 ENSDART00000127157
hlfa
hepatic leukemia factor a
chr15_-_22074315 0.35 ENSDART00000149830
drd2a
dopamine receptor D2a
chr12_+_48480632 0.35 ENSDART00000158157
arhgap44
Rho GTPase activating protein 44
chr4_+_72723304 0.35 ENSDART00000186791
ENSDART00000158902
ENSDART00000191925
rab3ip
RAB3A interacting protein (rabin3)
chr14_-_413273 0.34 ENSDART00000163976
ENSDART00000179907
FAT4
FAT atypical cadherin 4
chr3_-_26787430 0.34 ENSDART00000087047
rab40c
RAB40c, member RAS oncogene family
chr9_+_24159725 0.32 ENSDART00000137756
hecw2a
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a
chr5_-_31901468 0.32 ENSDART00000147814
ENSDART00000141446
coro1cb
coronin, actin binding protein, 1Cb
chr3_+_36424055 0.32 ENSDART00000170318
si:ch1073-443f11.2
si:ch1073-443f11.2
chr7_+_20471315 0.31 ENSDART00000173714
si:dkey-19b23.13
si:dkey-19b23.13
chr21_+_25802190 0.30 ENSDART00000128987
nf2b
neurofibromin 2b (merlin)
chr4_+_77943184 0.30 ENSDART00000159094
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr15_-_17619306 0.29 ENSDART00000184011
adamts15b
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr8_-_16712111 0.28 ENSDART00000184147
ENSDART00000180419
ENSDART00000076600
rpe65c
retinal pigment epithelium-specific protein 65c
chr6_-_34838397 0.27 ENSDART00000060169
ENSDART00000169605
mier1a
mesoderm induction early response 1a, transcriptional regulator
chr22_-_19552796 0.27 ENSDART00000148088
ENSDART00000105485
si:dkey-78l4.14
si:dkey-78l4.14
chr23_-_16485190 0.25 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr6_-_35052145 0.25 ENSDART00000073970
ENSDART00000185790
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr16_-_12173399 0.24 ENSDART00000142574
clstn3
calsyntenin 3
chr1_-_15797663 0.24 ENSDART00000177122
SGCZ
sarcoglycan zeta
chr1_+_54124209 0.23 ENSDART00000187730
LO017722.1

chr21_-_17482465 0.22 ENSDART00000004548
barhl1b
BarH-like homeobox 1b
chr4_+_57881965 0.22 ENSDART00000162234
si:dkeyp-44b5.4
si:dkeyp-44b5.4
chr4_-_2219705 0.21 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr6_-_21582444 0.20 ENSDART00000151339
si:dkey-43k4.3
si:dkey-43k4.3
chr8_+_50953776 0.20 ENSDART00000013870
zgc:56596
zgc:56596
chr8_-_53926228 0.20 ENSDART00000015554
ubiad1
UbiA prenyltransferase domain containing 1
chr23_-_4409668 0.19 ENSDART00000081823
si:ch73-142c19.1
si:ch73-142c19.1
chr6_-_35052388 0.19 ENSDART00000181000
ENSDART00000170116
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr5_-_23843636 0.19 ENSDART00000193280
GBGT1 (1 of many)
si:ch211-135f11.5
chr22_-_22242884 0.19 ENSDART00000020937
hdgfl2
HDGF like 2
chr15_-_14552101 0.19 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr5_+_41477954 0.18 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr12_-_48006835 0.17 ENSDART00000108989
adamts14
ADAM metallopeptidase with thrombospondin type 1 motif, 14
chr24_-_40860603 0.17 ENSDART00000188032
CU633479.7

chr25_-_13490744 0.16 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr9_+_37152564 0.16 ENSDART00000189497
gli2a
GLI family zinc finger 2a
chr5_-_38094130 0.16 ENSDART00000131831
si:ch211-284e13.4
si:ch211-284e13.4
chr23_-_17509656 0.15 ENSDART00000148423
dnajc5ab
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr10_+_42423318 0.14 ENSDART00000134282
npy8ar
neuropeptide Y receptor Y8a
chr25_+_4855549 0.12 ENSDART00000163839
ap4e1
adaptor-related protein complex 4, epsilon 1 subunit
chr10_-_2524917 0.12 ENSDART00000188642
CU856539.1

chr17_+_31914877 0.11 ENSDART00000177801
FAM196A (1 of many)
family with sequence similarity 196 member A
chr10_-_2524297 0.11 ENSDART00000192475
CU856539.1

chr18_+_46382484 0.11 ENSDART00000024202
ENSDART00000142790
daw1
dynein assembly factor with WDR repeat domains 1
chr20_+_11731039 0.10 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
si:ch211-155o21.3
chr17_+_22577472 0.10 ENSDART00000045099
yipf4
Yip1 domain family, member 4
chr4_+_5255041 0.10 ENSDART00000137966
ccdc167
coiled-coil domain containing 167
chr22_-_13466246 0.10 ENSDART00000134035
cntnap5b
contactin associated protein-like 5b
chr5_+_41477526 0.08 ENSDART00000153567
pias2
protein inhibitor of activated STAT, 2
chr3_+_45687266 0.08 ENSDART00000131652
gpr146
G protein-coupled receptor 146
chr17_-_40956035 0.08 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr21_-_22635245 0.07 ENSDART00000115224
ENSDART00000101782
nectin1a
nectin cell adhesion molecule 1a
chr3_-_48716422 0.07 ENSDART00000164979
si:ch211-114m9.1
si:ch211-114m9.1
chr5_-_30620625 0.07 ENSDART00000098273
tcnl
transcobalamin like
chr24_+_26329018 0.07 ENSDART00000145752
mynn
myoneurin
chr20_-_28642061 0.06 ENSDART00000135513
rgs6
regulator of G protein signaling 6
chr17_+_49281597 0.06 ENSDART00000155599
zgc:113176
zgc:113176
chr23_-_1660708 0.06 ENSDART00000175138
CU693481.1

chr24_+_26328787 0.05 ENSDART00000003884
mynn
myoneurin
chr17_+_28533102 0.04 ENSDART00000156218
mdga2a
MAM domain containing glycosylphosphatidylinositol anchor 2a
chr16_+_13965923 0.02 ENSDART00000103857
zgc:162509
zgc:162509
chr23_+_17509794 0.01 ENSDART00000148457
gid8b
GID complex subunit 8 homolog b (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of lhx1a+lhx1b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.4 1.9 GO:0000012 single strand break repair(GO:0000012)
0.2 0.6 GO:0034214 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.2 1.3 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 2.2 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 1.4 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 1.2 GO:0072506 phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.1 0.7 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.4 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 3.4 GO:0007568 aging(GO:0007568)
0.1 1.0 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 1.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.7 GO:0046822 regulation of nucleocytoplasmic transport(GO:0046822)
0.1 0.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.4 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.3 GO:0016122 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.1 2.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.2 GO:0071498 vitamin K metabolic process(GO:0042373) cellular response to fluid shear stress(GO:0071498)
0.1 0.7 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.1 1.0 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 1.0 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 5.5 GO:0033339 pectoral fin development(GO:0033339)
0.1 1.3 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.2 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.0 0.6 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 1.2 GO:0030814 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.0 0.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.4 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 1.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.4 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 1.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.3 GO:0001765 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0044406 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.0 0.2 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 1.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.6 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.0 0.1 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 0.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.5 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.5 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.7 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 1.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.3 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 1.2 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.0 GO:0021611 facial nerve formation(GO:0021611)
0.0 1.8 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.9 GO:0043484 regulation of RNA splicing(GO:0043484)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0019815 B cell receptor complex(GO:0019815)
0.2 0.7 GO:0032838 cell projection cytoplasm(GO:0032838)
0.1 0.5 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.7 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.4 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.5 GO:0030891 VCB complex(GO:0030891)
0.1 0.3 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.0 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.0 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 2.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.6 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.8 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.6 GO:0030496 midbody(GO:0030496)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.3 1.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 1.9 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 0.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 1.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.5 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.9 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 2.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 1.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.4 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 0.3 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.1 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 1.2 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 1.3 GO:0016208 AMP binding(GO:0016208)
0.0 0.6 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 1.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 1.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.7 GO:0003684 damaged DNA binding(GO:0003684)
0.0 2.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 1.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.2 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 1.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE