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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for lhx2b+lhx9

Z-value: 0.55

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Transcription factors associated with lhx2b+lhx9

Gene Symbol Gene ID Gene Info
lhx2b
ENSDARG00000031222 LIM homeobox 2b
lhx9
ENSDARG00000056979 LIM homeobox 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lhx9dr11_v1_chr22_-_23253481_23253481-0.285.5e-03Click!
lhx2bdr11_v1_chr8_+_3085120_3085219-0.197.1e-02Click!

Activity profile of lhx2b+lhx9 motif

Sorted Z-values of lhx2b+lhx9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_17776981 6.97 ENSDART00000141693
ccl19b
chemokine (C-C motif) ligand 19b
chr25_+_8356707 5.23 ENSDART00000153708
muc5.1
mucin 5.1, oligomeric mucus/gel-forming
chr21_+_25236297 4.83 ENSDART00000112783
tmem45b
transmembrane protein 45B
chr25_-_21031007 4.45 ENSDART00000138985
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr12_-_35830625 4.05 ENSDART00000180028
CU459056.1

chr12_-_4243268 4.04 ENSDART00000131275
zgc:92313
zgc:92313
chr5_-_63302944 4.02 ENSDART00000047110
gsnb
gelsolin b
chr16_-_9675982 3.91 ENSDART00000113724
mal2
mal, T cell differentiation protein 2 (gene/pseudogene)
chr9_-_9415000 3.82 ENSDART00000146210
si:ch211-214p13.9
si:ch211-214p13.9
chr12_+_37401331 3.42 ENSDART00000125040
si:ch211-152f22.4
si:ch211-152f22.4
chr20_+_28364742 3.34 ENSDART00000103355
rhov
ras homolog family member V
chr20_-_35750810 3.14 ENSDART00000153072
adgrf8
adhesion G protein-coupled receptor F8
chr21_-_44081540 3.11 ENSDART00000130833
FO704810.1

chr21_-_26114886 3.04 ENSDART00000139320
nipal4
NIPA-like domain containing 4
chr23_-_33350990 3.02 ENSDART00000144831
si:ch211-226m16.2
si:ch211-226m16.2
chr8_+_52637507 2.78 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr14_-_4145594 2.70 ENSDART00000077348
casp3b
caspase 3, apoptosis-related cysteine peptidase b
chr24_+_38301080 2.63 ENSDART00000105672
mybpc2b
myosin binding protein C, fast type b
chr1_+_9966384 2.61 ENSDART00000132607
si:dkeyp-75b4.8
si:dkeyp-75b4.8
chr5_+_27897504 2.54 ENSDART00000130936
adam28
ADAM metallopeptidase domain 28
chr8_+_34731982 2.44 ENSDART00000066050
hpdb
4-hydroxyphenylpyruvate dioxygenase b
chr20_+_98179 2.38 ENSDART00000022725
si:ch1073-155h21.1
si:ch1073-155h21.1
chr7_+_6652967 2.34 ENSDART00000102681
pnp5a
purine nucleoside phosphorylase 5a
chr5_+_27898226 2.33 ENSDART00000098604
ENSDART00000180251
adam28
ADAM metallopeptidase domain 28
chr3_+_26145013 2.18 ENSDART00000162546
ENSDART00000129561
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr14_-_14659023 2.17 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
nsdhl
NAD(P) dependent steroid dehydrogenase-like
chr5_-_30715225 2.14 ENSDART00000016758
ftr82
finTRIM family, member 82
chr23_+_36460239 2.11 ENSDART00000172441
lima1a
LIM domain and actin binding 1a
chr25_+_29474982 2.05 ENSDART00000130410
il17rel
interleukin 17 receptor E-like
chr21_+_13387965 2.05 ENSDART00000134347
zgc:113162
zgc:113162
chr7_-_66868543 2.04 ENSDART00000149680
ampd3a
adenosine monophosphate deaminase 3a
chr7_+_57088920 2.04 ENSDART00000024076
scamp2l
secretory carrier membrane protein 2, like
chr22_-_10156581 2.02 ENSDART00000168304
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr4_-_9891874 2.01 ENSDART00000067193
adm2a
adrenomedullin 2a
chr23_+_384850 1.95 ENSDART00000114000
zgc:101663
zgc:101663
chr19_+_2631565 1.94 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr6_-_35046735 1.94 ENSDART00000143649
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr14_-_33481428 1.91 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr8_-_31062811 1.89 ENSDART00000142528
slc20a1a
solute carrier family 20, member 1a
chr20_-_49889111 1.88 ENSDART00000058858
kif13bb
kinesin family member 13Bb
chr23_-_29394505 1.85 ENSDART00000017728
pgd
phosphogluconate dehydrogenase
chr10_+_29850330 1.83 ENSDART00000168898
hspa8
heat shock protein 8
chr19_+_14573998 1.82 ENSDART00000022076
fam46bb
family with sequence similarity 46, member Bb
chr13_+_18321140 1.80 ENSDART00000180947
eif4e1c
eukaryotic translation initiation factor 4E family member 1c
chr16_-_22294265 1.78 ENSDART00000124718
aqp10a
aquaporin 10a
chr20_+_48116476 1.75 ENSDART00000043938
tram2
translocation associated membrane protein 2
chr3_-_29941357 1.70 ENSDART00000147732
ENSDART00000137973
ENSDART00000103523
grna
granulin a
chr17_-_27048537 1.70 ENSDART00000050018
ENSDART00000193861
cnksr1
connector enhancer of kinase suppressor of Ras 1
chr18_+_14684115 1.69 ENSDART00000108469
spata2l
spermatogenesis associated 2-like
chr3_-_57666518 1.68 ENSDART00000102062
timp2b
TIMP metallopeptidase inhibitor 2b
chr2_+_36112273 1.68 ENSDART00000191315
traj35
T-cell receptor alpha joining 35
chr19_+_43297546 1.65 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr19_+_1688727 1.60 ENSDART00000115136
ENSDART00000166744
dennd3a
DENN/MADD domain containing 3a
chr3_+_29941777 1.59 ENSDART00000113889
ifi35
interferon-induced protein 35
chr10_+_35358675 1.59 ENSDART00000193263
si:dkey-259j3.5
si:dkey-259j3.5
chr13_-_31008275 1.55 ENSDART00000139394
wdfy4
WDFY family member 4
chr16_+_28994709 1.55 ENSDART00000088023
gon4l
gon-4-like (C. elegans)
chr5_-_57723929 1.54 ENSDART00000144237
gig2p
grass carp reovirus (GCRV)-induced gene 2p
chr12_+_20641471 1.54 ENSDART00000133654
calcoco2
calcium binding and coiled-coil domain 2
chr8_-_20230559 1.54 ENSDART00000193677
mllt1a
MLLT1, super elongation complex subunit a
chr23_-_36446307 1.52 ENSDART00000136623
zgc:174906
zgc:174906
chr23_-_30041065 1.50 ENSDART00000131209
ENSDART00000127192
ccdc187
coiled-coil domain containing 187
chr13_+_7442023 1.48 ENSDART00000080975
tnfaip2b
tumor necrosis factor, alpha-induced protein 2b
chr2_+_9990491 1.48 ENSDART00000011906
slc35a3b
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr8_+_11425048 1.47 ENSDART00000018739
tjp2b
tight junction protein 2b (zona occludens 2)
chr5_+_38752287 1.47 ENSDART00000133571
cxcl11.8
chemokine (C-X-C motif) ligand 11, duplicate 8
chr11_+_705727 1.46 ENSDART00000165366
timp4.2
TIMP metallopeptidase inhibitor 4, tandem duplicate 2
chr24_-_32582880 1.46 ENSDART00000186307
rdh12l
retinol dehydrogenase 12, like
chr7_-_51368681 1.45 ENSDART00000146385
arhgap36
Rho GTPase activating protein 36
chr19_-_5669122 1.45 ENSDART00000112211
si:ch211-264f5.2
si:ch211-264f5.2
chr14_+_901847 1.45 ENSDART00000166991
si:ch73-208h1.2
si:ch73-208h1.2
chr19_+_43359075 1.42 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
yrk
Yes-related kinase
chr7_+_65673885 1.41 ENSDART00000169182
parvab
parvin, alpha b
chr6_-_43677125 1.40 ENSDART00000150128
foxp1b
forkhead box P1b
chr9_+_21277846 1.39 ENSDART00000139620
ENSDART00000110996
ENSDART00000111899
lats2
large tumor suppressor kinase 2
chr16_+_54209504 1.37 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr24_-_26622423 1.36 ENSDART00000182044
tnikb
TRAF2 and NCK interacting kinase b
chr9_-_43644261 1.36 ENSDART00000023684
cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr10_+_2742499 1.36 ENSDART00000122847
grk5
G protein-coupled receptor kinase 5
chr14_+_15257658 1.35 ENSDART00000161625
ENSDART00000193577
si:dkey-77g12.4
si:dkey-203a12.5
si:dkey-77g12.4
si:dkey-203a12.5
chr5_-_66397688 1.35 ENSDART00000161483
hip1rb
huntingtin interacting protein 1 related b
chr10_-_43771447 1.33 ENSDART00000052307
arrdc3b
arrestin domain containing 3b
chr15_-_43284021 1.32 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr7_-_71531846 1.31 ENSDART00000111797
acer2
alkaline ceramidase 2
chr4_+_77943184 1.30 ENSDART00000159094
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr7_-_54320088 1.29 ENSDART00000172396
fadd
Fas (tnfrsf6)-associated via death domain
chr2_+_48073972 1.29 ENSDART00000186442
klf6b
Kruppel-like factor 6b
chr8_-_25771474 1.28 ENSDART00000193883
suv39h1b
suppressor of variegation 3-9 homolog 1b
chr9_+_34641237 1.28 ENSDART00000133996
shox
short stature homeobox
chr19_+_12237945 1.28 ENSDART00000190034
grhl2b
grainyhead-like transcription factor 2b
chr11_+_42474694 1.27 ENSDART00000056048
ENSDART00000184710
si:ch1073-165f9.2
si:ch1073-165f9.2
chr17_+_44697604 1.26 ENSDART00000156625
pgfb
placental growth factor b
chr3_-_32818607 1.26 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr11_+_40812590 1.25 ENSDART00000186690
errfi1a
ERBB receptor feedback inhibitor 1a
chr6_+_40922572 1.21 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr4_-_42408339 1.20 ENSDART00000172612
si:ch211-59d8.3
si:ch211-59d8.3
chr22_+_5687615 1.19 ENSDART00000133241
ENSDART00000019854
ENSDART00000138102
dnase1l4.2
deoxyribonuclease 1 like 4, tandem duplicate 2
chr21_+_45223194 1.19 ENSDART00000150902
si:ch73-269m14.3
si:ch73-269m14.3
chr22_+_508290 1.16 ENSDART00000135403
nuak2
NUAK family, SNF1-like kinase, 2
chr12_+_20641102 1.15 ENSDART00000152964
calcoco2
calcium binding and coiled-coil domain 2
chr20_+_25225112 1.14 ENSDART00000153088
ENSDART00000127291
ENSDART00000130494
moxd1
monooxygenase, DBH-like 1
chr3_+_53352018 1.12 ENSDART00000082715
camsap3
calmodulin regulated spectrin-associated protein family, member 3
chr17_+_8799451 1.11 ENSDART00000189814
ENSDART00000191577
tonsl
tonsoku-like, DNA repair protein
chr5_+_13647288 1.10 ENSDART00000099660
ENSDART00000139199
h2afva
H2A histone family, member Va
chr13_-_38730267 1.10 ENSDART00000157524
lmbrd1
LMBR1 domain containing 1
chr8_-_20230802 1.10 ENSDART00000063400
mllt1a
MLLT1, super elongation complex subunit a
chr20_-_44557037 1.09 ENSDART00000140995
mfsd2b
major facilitator superfamily domain containing 2B
chr12_-_18578432 1.09 ENSDART00000122858
zdhhc4
zinc finger, DHHC-type containing 4
chr17_-_20558961 1.09 ENSDART00000155993
sh3pxd2ab
SH3 and PX domains 2Ab
chr17_-_26935339 1.09 ENSDART00000139946
nipal3
NIPA-like domain containing 3
chr21_+_11885404 1.08 ENSDART00000092015
dcaf12
DDB1 and CUL4 associated factor 12
chr3_-_32079916 1.08 ENSDART00000040900
baxb
BCL2 associated X, apoptosis regulator b
chr2_-_36918709 1.08 ENSDART00000084876
zgc:153654
zgc:153654
chr3_+_13559199 1.08 ENSDART00000166547
si:ch73-106n3.1
si:ch73-106n3.1
chr5_+_2815021 1.07 ENSDART00000020472
hpda
4-hydroxyphenylpyruvate dioxygenase a
chr20_-_40755614 1.07 ENSDART00000061247
cx32.3
connexin 32.3
chr25_+_3217419 1.05 ENSDART00000104859
rccd1
RCC1 domain containing 1
chr25_+_11008419 1.05 ENSDART00000156589
mhc1lia
major histocompatibility complex class I LIA
chr6_+_35362225 1.05 ENSDART00000133783
ENSDART00000102483
rgs4
regulator of G protein signaling 4
chr6_+_12527725 1.02 ENSDART00000149328
stk24b
serine/threonine kinase 24b (STE20 homolog, yeast)
chr4_-_62714083 1.01 ENSDART00000188299
si:dkey-28k24.2
si:dkey-28k24.2
chr23_+_4709607 1.01 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
raf1a
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr13_-_52089003 1.01 ENSDART00000187600
tmem254
transmembrane protein 254
chr11_-_45135643 1.00 ENSDART00000170863
cant1b
calcium activated nucleotidase 1b
chr9_+_21165484 1.00 ENSDART00000177286
si:rp71-68n21.9
si:rp71-68n21.9
chr23_-_31969786 1.00 ENSDART00000134550
ormdl2
ORMDL sphingolipid biosynthesis regulator 2
chr2_+_20605925 0.99 ENSDART00000191510
olfml2bb
olfactomedin-like 2Bb
chr2_+_105748 0.96 ENSDART00000169601
CABZ01098670.1

chr16_+_24733741 0.95 ENSDART00000155217
si:dkey-79d12.4
si:dkey-79d12.4
chr11_+_34921492 0.95 ENSDART00000128070
gnai2a
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a
chr22_-_5252005 0.94 ENSDART00000132942
ENSDART00000081801
ncln
nicalin
chr7_-_8738827 0.93 ENSDART00000172807
ENSDART00000173026
si:ch211-1o7.3
si:ch211-1o7.3
chr15_-_40157165 0.93 ENSDART00000192991
si:ch211-281l24.3
si:ch211-281l24.3
chr9_+_37152564 0.91 ENSDART00000189497
gli2a
GLI family zinc finger 2a
chr6_-_44402358 0.91 ENSDART00000193007
ENSDART00000193603
pdzrn3b
PDZ domain containing RING finger 3b
chr6_-_44402151 0.90 ENSDART00000114330
pdzrn3b
PDZ domain containing RING finger 3b
chr4_-_71904377 0.90 ENSDART00000191852
si:dkeyp-4f2.1
si:dkeyp-4f2.1
chr12_-_18578218 0.89 ENSDART00000125803
zdhhc4
zinc finger, DHHC-type containing 4
chr8_-_2616326 0.88 ENSDART00000027214
slc25a25a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a
chr20_+_25586099 0.88 ENSDART00000063122
ENSDART00000134047
cyp2p10
cytochrome P450, family 2, subfamily P, polypeptide 10
chr2_-_9989919 0.87 ENSDART00000180213
ENSDART00000184369
imp3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr6_+_24420523 0.87 ENSDART00000185461
tgfbr3
transforming growth factor, beta receptor III
chr4_+_966061 0.86 ENSDART00000122535
rpap3
RNA polymerase II associated protein 3
chr7_+_22809905 0.85 ENSDART00000166900
ENSDART00000143455
ENSDART00000126037
sf1
splicing factor 1
chr2_+_44571200 0.85 ENSDART00000098132
klhl24a
kelch-like family member 24a
chr4_+_16885854 0.84 ENSDART00000017726
etnk1
ethanolamine kinase 1
chr22_+_19366866 0.83 ENSDART00000137301
si:dkey-21e2.12
si:dkey-21e2.12
chr18_+_35128685 0.83 ENSDART00000151579
si:ch211-195m9.3
si:ch211-195m9.3
chr5_+_872299 0.82 ENSDART00000130042
fubp3
far upstream element (FUSE) binding protein 3
chr2_+_10878406 0.81 ENSDART00000091497
tceanc2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr19_+_7895086 0.81 ENSDART00000132180
si:dkey-266f7.1
si:dkey-266f7.1
chr9_-_47472998 0.81 ENSDART00000134480
tns1b
tensin 1b
chr23_-_20051369 0.80 ENSDART00000049836
bgnb
biglycan b
chr8_+_28695914 0.79 ENSDART00000033386
ocstamp
osteoclast stimulatory transmembrane protein
chr8_+_25079470 0.78 ENSDART00000000744
sypl2b
synaptophysin-like 2b
chr8_+_36560019 0.78 ENSDART00000136418
ENSDART00000061378
ENSDART00000185237
sf3a1
splicing factor 3a, subunit 1
chr3_-_15999501 0.77 ENSDART00000160668
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr2_-_55797318 0.77 ENSDART00000158147
calr3b
calreticulin 3b
chr21_-_19314618 0.77 ENSDART00000188744
gpat3
glycerol-3-phosphate acyltransferase 3
chr8_-_30204650 0.76 ENSDART00000133209
zgc:162939
zgc:162939
chr12_+_20587179 0.74 ENSDART00000170127
arsg
arylsulfatase G
chr6_-_40029423 0.73 ENSDART00000103230
pfkfb4b
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b
chr11_+_45436703 0.73 ENSDART00000168295
ENSDART00000173293
sos1
son of sevenless homolog 1 (Drosophila)
chr23_-_42232124 0.73 ENSDART00000149944
gpx7
glutathione peroxidase 7
chr5_-_23843636 0.73 ENSDART00000193280
GBGT1 (1 of many)
si:ch211-135f11.5
chr1_+_47499888 0.72 ENSDART00000027624
stn1
STN1, CST complex subunit
chr19_+_43780970 0.72 ENSDART00000063870
rpl11
ribosomal protein L11
chr22_+_5532003 0.72 ENSDART00000106174
si:ch73-256j6.2
si:ch73-256j6.2
chr9_-_30555725 0.72 ENSDART00000079222
chaf1b
chromatin assembly factor 1, subunit B
chr22_+_9522971 0.71 ENSDART00000110048
strip1
striatin interacting protein 1
chr12_-_35054354 0.71 ENSDART00000075351
zgc:112285
zgc:112285
chr13_-_9875538 0.69 ENSDART00000041609
tm9sf3
transmembrane 9 superfamily member 3
chr3_+_3681116 0.69 ENSDART00000109618
art4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr3_-_26806032 0.69 ENSDART00000143710
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr21_-_1644414 0.68 ENSDART00000105736
ENSDART00000124904
zgc:152948
zgc:152948
chr15_-_39969988 0.68 ENSDART00000146054
rps5
ribosomal protein S5
chr16_-_42965192 0.68 ENSDART00000113714
mtx1a
metaxin 1a
chr25_+_21833287 0.67 ENSDART00000187606
ckmt1
creatine kinase, mitochondrial 1
chr8_-_12867128 0.66 ENSDART00000142201
slc2a6
solute carrier family 2 (facilitated glucose transporter), member 6
chr16_+_3068080 0.66 ENSDART00000160092
cyb5r4
cytochrome b5 reductase 4
chr4_-_1908179 0.66 ENSDART00000139586
ano6
anoctamin 6
chr12_+_47698356 0.65 ENSDART00000112010
lzts2b
leucine zipper, putative tumor suppressor 2b
chr19_-_11157659 0.64 ENSDART00000146557
si:dkey-240h12.3
si:dkey-240h12.3
chr13_+_33268657 0.64 ENSDART00000002095
tmem39b
transmembrane protein 39B
chr7_-_34448076 0.63 ENSDART00000170935
nr1h3
nuclear receptor subfamily 1, group H, member 3
chr1_-_51038885 0.62 ENSDART00000035150
spast
spastin
chr24_-_40860603 0.61 ENSDART00000188032
CU633479.7

chr15_-_38129845 0.60 ENSDART00000057095
si:dkey-24p1.1
si:dkey-24p1.1
chr18_+_17725410 0.60 ENSDART00000090608
rspry1
ring finger and SPRY domain containing 1
chr23_-_25779995 0.60 ENSDART00000110670
si:dkey-21c19.3
si:dkey-21c19.3
chr20_-_28352352 0.58 ENSDART00000128806
ino80
INO80 complex subunit
chr7_+_71664624 0.57 ENSDART00000170273
emilin2b
elastin microfibril interfacer 2b
chr10_-_11261565 0.57 ENSDART00000146727
ptbp3
polypyrimidine tract binding protein 3
chr17_+_8799661 0.56 ENSDART00000105326
tonsl
tonsoku-like, DNA repair protein
chr5_-_66823750 0.55 ENSDART00000041441
ENSDART00000112488
stip1
stress-induced phosphoprotein 1
chr22_+_37631234 0.55 ENSDART00000007346
psmd1
proteasome 26S subunit, non-ATPase 1
chr4_-_67980261 0.55 ENSDART00000182305
si:ch211-223k15.1
si:ch211-223k15.1
chr23_-_45504991 0.54 ENSDART00000148761
col24a1
collagen type XXIV alpha 1
chr6_-_15491579 0.54 ENSDART00000156439
st6gal2b
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2b
chr21_-_25801956 0.54 ENSDART00000101219
mettl27
methyltransferase like 27

Network of associatons between targets according to the STRING database.

First level regulatory network of lhx2b+lhx9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.8 3.9 GO:0045056 transcytosis(GO:0045056)
0.6 3.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.5 2.2 GO:0045988 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.5 3.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.4 2.0 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.4 1.1 GO:0042420 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.3 1.3 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.3 1.8 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.3 1.5 GO:0000012 single strand break repair(GO:0000012)
0.3 3.0 GO:0006032 chitin catabolic process(GO:0006032)
0.2 1.0 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.2 4.1 GO:0015693 magnesium ion transport(GO:0015693)
0.2 0.9 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.2 4.0 GO:0030216 keratinocyte differentiation(GO:0030216)
0.2 0.7 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.2 1.7 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.2 0.6 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.2 0.6 GO:0051230 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.2 1.9 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.2 1.8 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.2 1.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 7.0 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.2 0.9 GO:2000381 negative regulation of nodal signaling pathway(GO:1900108) negative regulation of mesoderm development(GO:2000381)
0.2 1.9 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 1.9 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 1.5 GO:0051601 exocyst localization(GO:0051601)
0.1 2.0 GO:0032264 IMP salvage(GO:0032264)
0.1 1.3 GO:0070836 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 4.0 GO:0051014 actin filament severing(GO:0051014)
0.1 0.9 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.6 GO:0042766 nucleosome mobilization(GO:0042766)
0.1 1.3 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.1 1.4 GO:0046620 secondary heart field specification(GO:0003139) regulation of organ growth(GO:0046620)
0.1 2.5 GO:0030183 B cell differentiation(GO:0030183)
0.1 1.3 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.3 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 1.1 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.1 1.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.5 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 1.1 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 0.5 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 0.9 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 1.5 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 0.8 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 1.9 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.7 GO:0051013 microtubule severing(GO:0051013)
0.1 1.7 GO:0031297 replication fork processing(GO:0031297)
0.1 0.1 GO:0033572 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.1 1.2 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 1.9 GO:0006801 superoxide metabolic process(GO:0006801)
0.1 6.7 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 1.0 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.5 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 0.4 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.1 2.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 1.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.7 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.1 1.0 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 2.2 GO:0001878 response to yeast(GO:0001878)
0.1 0.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.7 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.1 GO:0097053 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.0 0.8 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.5 GO:0043931 ossification involved in bone maturation(GO:0043931) bone maturation(GO:0070977)
0.0 0.4 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.4 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.4 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 1.1 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.6 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 1.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.7 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.4 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 2.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.6 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 3.0 GO:0006413 translational initiation(GO:0006413)
0.0 1.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.3 GO:0050779 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.0 1.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.9 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 1.8 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.2 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 1.3 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.8 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 1.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.9 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 4.7 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.1 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.0 1.3 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.4 GO:0032526 response to retinoic acid(GO:0032526)
0.0 1.4 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0006516 glycoprotein catabolic process(GO:0006516)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.8 GO:0019815 B cell receptor complex(GO:0019815)
0.6 1.9 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.5 2.2 GO:0031673 H zone(GO:0031673)
0.4 1.1 GO:0034515 proteasome storage granule(GO:0034515)
0.3 0.9 GO:0034457 Mpp10 complex(GO:0034457)
0.2 1.0 GO:0035339 SPOTS complex(GO:0035339)
0.2 0.7 GO:1990879 CST complex(GO:1990879)
0.2 1.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 1.4 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.2 2.0 GO:0071797 LUBAC complex(GO:0071797)
0.2 0.5 GO:0005592 collagen type XI trimer(GO:0005592)
0.2 0.7 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.1 GO:0036449 microtubule minus-end(GO:0036449)
0.1 2.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.4 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 1.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.7 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 5.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.5 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 5.2 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.1 GO:0030667 secretory granule membrane(GO:0030667)
0.0 5.4 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.6 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.8 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.4 GO:0031010 ISWI-type complex(GO:0031010)
0.0 2.2 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.0 1.3 GO:0030496 midbody(GO:0030496)
0.0 8.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 2.0 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 15.4 GO:0005615 extracellular space(GO:0005615)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.5 GO:0005925 focal adhesion(GO:0005925)
0.0 4.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.7 2.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.4 1.8 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.4 1.9 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.4 1.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.3 4.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.3 4.4 GO:0002020 protease binding(GO:0002020)
0.3 3.0 GO:0004568 chitinase activity(GO:0004568)
0.3 2.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 2.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 4.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 1.5 GO:0031419 cobalamin binding(GO:0031419)
0.2 2.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 2.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 2.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 7.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.2 0.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 1.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 1.5 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 1.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 2.7 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 2.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.5 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.1 1.9 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 1.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 1.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 1.8 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.5 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.8 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 1.1 GO:0030507 spectrin binding(GO:0030507)
0.1 1.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 4.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.7 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.5 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.7 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 0.7 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.2 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.7 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 2.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.9 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.3 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 6.6 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 5.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.4 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.8 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 2.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 1.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.9 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 1.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 2.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.7 PID IL3 PATHWAY IL3-mediated signaling events
0.1 0.7 PID IGF1 PATHWAY IGF1 pathway
0.0 1.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.5 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 1.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.4 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 1.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 0.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.7 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 4.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation