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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for lhx6

Z-value: 0.76

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Transcription factors associated with lhx6

Gene Symbol Gene ID Gene Info
lhx6
ENSDARG00000006896 LIM homeobox 6
lhx6
ENSDARG00000112520 LIM homeobox 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lhx6dr11_v1_chr10_+_9372702_9372702-0.103.2e-01Click!

Activity profile of lhx6 motif

Sorted Z-values of lhx6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_15433671 11.40 ENSDART00000149568
fabp7a
fatty acid binding protein 7, brain, a
chr17_+_15433518 11.34 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr20_-_9436521 11.01 ENSDART00000133000
zgc:101840
zgc:101840
chr5_+_64732036 8.22 ENSDART00000073950
olfm1a
olfactomedin 1a
chr4_+_21129752 8.18 ENSDART00000169764
syt1a
synaptotagmin Ia
chr5_+_64732270 7.82 ENSDART00000134241
olfm1a
olfactomedin 1a
chr7_+_30787903 6.93 ENSDART00000174000
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr1_-_50859053 6.46 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr8_+_16025554 6.04 ENSDART00000110171
elavl4
ELAV like neuron-specific RNA binding protein 4
chr5_-_50992690 5.56 ENSDART00000149553
ENSDART00000097460
ENSDART00000192021
hmgcra
3-hydroxy-3-methylglutaryl-CoA reductase a
chr16_+_46111849 5.15 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr14_+_14662116 5.10 ENSDART00000161693
cetn2
centrin, EF-hand protein, 2
chr25_-_13842618 5.05 ENSDART00000160258
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr7_-_49594995 4.99 ENSDART00000174161
ENSDART00000109147
brsk2b
BR serine/threonine kinase 2b
chr24_-_21923930 4.98 ENSDART00000131944
tagln3b
transgelin 3b
chr5_+_61301525 4.68 ENSDART00000128773
doc2b
double C2-like domains, beta
chr2_+_50608099 4.59 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr14_-_33872092 4.57 ENSDART00000111903
si:ch73-335m24.2
si:ch73-335m24.2
chr4_+_4849789 4.42 ENSDART00000130818
ENSDART00000127751
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr1_+_25801648 4.26 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr13_+_15838151 4.21 ENSDART00000008987
klc1a
kinesin light chain 1a
chr10_-_27049170 4.21 ENSDART00000143451
cnih2
cornichon family AMPA receptor auxiliary protein 2
chr21_+_15824182 4.14 ENSDART00000065779
gnrh2
gonadotropin-releasing hormone 2
chr17_-_36896560 4.09 ENSDART00000045287
mapre3a
microtubule-associated protein, RP/EB family, member 3a
chr19_-_9882821 4.08 ENSDART00000147128
cacng7a
calcium channel, voltage-dependent, gamma subunit 7a
chr19_-_5103313 4.00 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr14_-_33872616 3.91 ENSDART00000162840
si:ch73-335m24.2
si:ch73-335m24.2
chr2_+_26237322 3.86 ENSDART00000030520
palm1b
paralemmin 1b
chr21_-_39177564 3.76 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr4_+_11384891 3.69 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
pcloa
piccolo presynaptic cytomatrix protein a
chr19_-_5103141 3.66 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr3_+_45365098 3.63 ENSDART00000052746
ENSDART00000156555
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr11_-_44801968 3.60 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr3_+_45364849 3.54 ENSDART00000153974
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr8_+_49778486 3.53 ENSDART00000131732
ntrk2a
neurotrophic tyrosine kinase, receptor, type 2a
chr16_+_47207691 3.49 ENSDART00000062507
ica1
islet cell autoantigen 1
chr13_-_31435137 3.48 ENSDART00000057441
rtn1a
reticulon 1a
chr5_+_22098591 3.44 ENSDART00000143676
zc3h12b
zinc finger CCCH-type containing 12B
chr4_-_17629444 3.43 ENSDART00000108814
nrip2
nuclear receptor interacting protein 2
chr13_-_29420885 3.41 ENSDART00000024225
chata
choline O-acetyltransferase a
chr2_+_20332044 3.35 ENSDART00000112131
plppr4a
phospholipid phosphatase related 4a
chr7_+_56577522 3.34 ENSDART00000149130
ENSDART00000149624
hp
haptoglobin
chr21_+_28958471 3.25 ENSDART00000144331
ENSDART00000005929
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr13_+_38521152 3.15 ENSDART00000145292
adgrb3
adhesion G protein-coupled receptor B3
chr9_+_38372216 3.14 ENSDART00000141895
plcd4b
phospholipase C, delta 4b
chr9_+_17983463 3.14 ENSDART00000182150
akap11
A kinase (PRKA) anchor protein 11
chr17_+_24722646 3.14 ENSDART00000138356
mtfr1l
mitochondrial fission regulator 1-like
chr9_+_30108641 2.99 ENSDART00000060174
jagn1a
jagunal homolog 1a
chr20_-_29864390 2.98 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr4_-_1801519 2.97 ENSDART00000188604
ENSDART00000135749
nudt4b
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr19_-_30524952 2.96 ENSDART00000103506
hpcal4
hippocalcin like 4
chr4_-_28158335 2.95 ENSDART00000134605
gramd4a
GRAM domain containing 4a
chr14_+_8940326 2.93 ENSDART00000159920
rps6kal
ribosomal protein S6 kinase a, like
chr7_+_56577906 2.92 ENSDART00000184023
hp
haptoglobin
chr22_+_27090136 2.90 ENSDART00000136770
si:dkey-246e1.3
si:dkey-246e1.3
chr24_+_16547035 2.90 ENSDART00000164319
sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr1_-_18811517 2.90 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr3_+_34919810 2.89 ENSDART00000055264
ca10b
carbonic anhydrase Xb
chr19_+_233143 2.88 ENSDART00000175273
syngap1a
synaptic Ras GTPase activating protein 1a
chr16_+_34531486 2.78 ENSDART00000043291
paqr7b
progestin and adipoQ receptor family member VII, b
chr20_-_23226453 2.75 ENSDART00000142721
dcun1d4
DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)
chr10_+_21726853 2.74 ENSDART00000162869
pcdh1g14
protocadherin 1 gamma 14
chr11_+_11267829 2.72 ENSDART00000026814
ENSDART00000173346
ENSDART00000151926
ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr13_-_24311628 2.67 ENSDART00000004420
rab4a
RAB4a, member RAS oncogene family
chr15_-_9272328 2.67 ENSDART00000172114
calm2a
calmodulin 2a (phosphorylase kinase, delta)
chr20_-_46362606 2.62 ENSDART00000153087
bmf2
BCL2 modifying factor 2
chr21_+_26748141 2.61 ENSDART00000169025
pcxa
pyruvate carboxylase a
chr18_+_8320165 2.61 ENSDART00000092053
chkb
choline kinase beta
chr7_-_28148310 2.57 ENSDART00000044208
lmo1
LIM domain only 1
chr23_+_40460333 2.56 ENSDART00000184658
soga3b
SOGA family member 3b
chr11_+_18873619 2.54 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr5_+_36768674 2.51 ENSDART00000146854
mark4a
MAP/microtubule affinity-regulating kinase 4a
chr9_-_20372977 2.49 ENSDART00000113418
igsf3
immunoglobulin superfamily, member 3
chr22_+_5176255 2.48 ENSDART00000092647
cers1
ceramide synthase 1
chr20_-_14114078 2.47 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
si:ch211-223m11.2
chr6_-_6487876 2.47 ENSDART00000137642
cep170ab
centrosomal protein 170Ab
chr2_+_6253246 2.46 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr23_+_28582865 2.43 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr2_+_40294313 2.42 ENSDART00000037292
epha4b
eph receptor A4b
chr15_-_33925851 2.42 ENSDART00000187807
ENSDART00000187780
mag
myelin associated glycoprotein
chr11_+_38280454 2.41 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr13_+_19322686 2.37 ENSDART00000058036
emx2
empty spiracles homeobox 2
chr5_+_60590796 2.27 ENSDART00000159859
tmem132e
transmembrane protein 132E
chr23_-_10786400 2.27 ENSDART00000055038
rybpa
RING1 and YY1 binding protein a
chr18_+_7639401 2.26 ENSDART00000092416
rabl2
RAB, member of RAS oncogene family-like 2
chr22_-_20166660 2.25 ENSDART00000085913
ENSDART00000188241
btbd2a
BTB (POZ) domain containing 2a
chr10_-_5581487 2.25 ENSDART00000141943
syk
spleen tyrosine kinase
chr12_-_4781801 2.24 ENSDART00000167490
ENSDART00000121718
mapta
microtubule-associated protein tau a
chr11_+_18873113 2.23 ENSDART00000103969
ENSDART00000103968
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr23_-_18130264 2.22 ENSDART00000016976
nucks1b
nuclear casein kinase and cyclin-dependent kinase substrate 1b
chr18_-_2433011 2.21 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr20_-_48485354 2.15 ENSDART00000124040
ENSDART00000148437
insm1a
insulinoma-associated 1a
chr17_-_49438873 2.13 ENSDART00000004424
znf292a
zinc finger protein 292a
chr6_-_55585423 2.12 ENSDART00000157129
slc12a5a
solute carrier family 12 (potassium/chloride transporter), member 5a
chr5_+_29851433 2.10 ENSDART00000143434
ubash3ba
ubiquitin associated and SH3 domain containing Ba
chr5_+_37903790 2.09 ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr21_+_42226113 2.07 ENSDART00000170362
GABRB2 (1 of many)
gamma-aminobutyric acid type A receptor beta2 subunit
chr15_+_23799461 2.04 ENSDART00000154885
si:ch211-167j9.4
si:ch211-167j9.4
chr22_-_24818066 2.01 ENSDART00000143443
vtg6
vitellogenin 6
chr6_+_21001264 1.95 ENSDART00000044519
ENSDART00000151278
cx44.2
connexin 44.2
chr7_-_30174882 1.92 ENSDART00000110409
frmd5
FERM domain containing 5
chr2_-_32558795 1.87 ENSDART00000140026
smarcd3a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr6_+_39232245 1.83 ENSDART00000187351
b4galnt1b
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr1_+_33668236 1.79 ENSDART00000122316
ENSDART00000102184
arl13b
ADP-ribosylation factor-like 13b
chr11_-_42554290 1.77 ENSDART00000130573
atp6ap1la
ATPase H+ transporting accessory protein 1 like a
chr5_-_16996482 1.77 ENSDART00000144501
galnt9
polypeptide N-acetylgalactosaminyltransferase 9
chr1_+_18811679 1.77 ENSDART00000078610
slc25a51a
solute carrier family 25, member 51a
chr25_-_19224298 1.77 ENSDART00000149917
acanb
aggrecan b
chr4_+_2655358 1.76 ENSDART00000007638
bcap29
B cell receptor associated protein 29
chr18_+_17827149 1.76 ENSDART00000190237
ENSDART00000189345
ZNF423
si:ch211-216l23.1
chr17_+_49281597 1.76 ENSDART00000155599
zgc:113176
zgc:113176
chr8_+_49778756 1.74 ENSDART00000083790
ntrk2a
neurotrophic tyrosine kinase, receptor, type 2a
chr1_-_12109216 1.73 ENSDART00000079930
mttp
microsomal triglyceride transfer protein
chr1_-_44701313 1.72 ENSDART00000193926
si:dkey-28b4.8
si:dkey-28b4.8
chr24_-_25004553 1.64 ENSDART00000080997
ENSDART00000136860
zdhhc20b
zinc finger, DHHC-type containing 20b
chr20_+_41021054 1.63 ENSDART00000146052
man1a1
mannosidase, alpha, class 1A, member 1
chr11_+_28476298 1.62 ENSDART00000122319
lrrc38b
leucine rich repeat containing 38b
chr19_-_42588510 1.61 ENSDART00000102583
sytl1
synaptotagmin-like 1
chr3_-_46817499 1.61 ENSDART00000013717
elavl3
ELAV like neuron-specific RNA binding protein 3
chr20_+_29209615 1.58 ENSDART00000062350
katnbl1
katanin p80 subunit B-like 1
chr3_+_62353650 1.56 ENSDART00000112428
iqck
IQ motif containing K
chr5_-_41307550 1.56 ENSDART00000143446
npr3
natriuretic peptide receptor 3
chr4_-_73756673 1.56 ENSDART00000174274
ENSDART00000192913
ENSDART00000113546
BX855614.4
si:dkey-262g12.14
zgc:171551

si:dkey-262g12.14
zgc:171551
chr12_+_41697664 1.55 ENSDART00000162302
bnip3
BCL2 interacting protein 3
chr20_+_29209767 1.54 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr5_-_64831207 1.52 ENSDART00000144816
lix1
limb and CNS expressed 1
chr17_-_40956035 1.51 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr6_+_28208973 1.51 ENSDART00000171216
ENSDART00000171377
ENSDART00000167389
ENSDART00000166988
LSM2 (1 of many)
si:ch73-14h10.2
chr7_-_59159253 1.50 ENSDART00000159285
haus6
HAUS augmin-like complex, subunit 6
chr15_+_17345609 1.50 ENSDART00000111753
vmp1
vacuole membrane protein 1
chr7_-_35708450 1.48 ENSDART00000193886
irx5a
iroquois homeobox 5a
chr14_-_16082806 1.46 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr8_-_49766205 1.46 ENSDART00000137941
ENSDART00000097919
ENSDART00000147309
hnrnpk
heterogeneous nuclear ribonucleoprotein K
chr21_-_14175838 1.44 ENSDART00000111659
whrna
whirlin a
chr3_-_43356082 1.42 ENSDART00000171213
uncx
UNC homeobox
chr5_-_19006290 1.41 ENSDART00000137022
golga3
golgin A3
chr17_-_200316 1.40 ENSDART00000190561
CABZ01083778.1

chr15_-_18115540 1.40 ENSDART00000131639
ENSDART00000047902
arcn1b
archain 1b
chr6_+_45918981 1.40 ENSDART00000149642
h6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr15_+_6114109 1.40 ENSDART00000184937
PCP4 (1 of many)
Purkinje cell protein 4
chr11_-_40728380 1.39 ENSDART00000023745
ccdc114
coiled-coil domain containing 114
chr11_+_41540862 1.38 ENSDART00000173210
kcnab2a
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr2_+_57848844 1.37 ENSDART00000037279
plekhj1
pleckstrin homology domain containing, family J member 1
chr24_-_39518599 1.37 ENSDART00000145606
ENSDART00000031486
lyrm1
LYR motif containing 1
chr16_-_26296477 1.36 ENSDART00000157553
erfl1
Ets2 repressor factor like 1
chr22_-_21897203 1.36 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
gna11a
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr7_+_38811800 1.36 ENSDART00000052322
zgc:110699
zgc:110699
chr10_-_34002185 1.34 ENSDART00000046599
zar1l
zygote arrest 1-like
chr2_+_35728033 1.33 ENSDART00000002094
ankrd45
ankyrin repeat domain 45
chr7_+_51795667 1.31 ENSDART00000174201
ENSDART00000073839
slc38a7
solute carrier family 38, member 7
chr16_+_23975930 1.31 ENSDART00000147858
ENSDART00000144347
ENSDART00000115270
apoc4
apolipoprotein C-IV
chr18_+_28106139 1.31 ENSDART00000089615
kiaa1549lb
KIAA1549-like b
chr14_+_23717165 1.29 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr23_-_36446307 1.27 ENSDART00000136623
zgc:174906
zgc:174906
chr15_+_21262917 1.26 ENSDART00000101000
gkup
glucuronokinase with putative uridyl pyrophosphorylase
chr14_+_25817628 1.26 ENSDART00000047680
glra1
glycine receptor, alpha 1
chr5_-_51619742 1.24 ENSDART00000188537
otpb
orthopedia homeobox b
chr20_+_29209926 1.23 ENSDART00000152949
ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr3_-_56541723 1.22 ENSDART00000156398
ENSDART00000050576
ENSDART00000184874
si:ch211-189a21.1
cyth1a
si:ch211-189a21.1
cytohesin 1a
chr7_-_26532089 1.21 ENSDART00000121698
senp3b
SUMO1/sentrin/SMT3 specific peptidase 3b
chr3_-_46811611 1.21 ENSDART00000134092
elavl3
ELAV like neuron-specific RNA binding protein 3
chr21_+_32820175 1.19 ENSDART00000076903
adra2db
adrenergic, alpha-2D-, receptor b
chr25_-_29087925 1.17 ENSDART00000171758
rpp25a
ribonuclease P and MRP subunit p25, a
chr19_+_22062202 1.17 ENSDART00000100181
sall3b
spalt-like transcription factor 3b
chr12_-_35393211 1.15 ENSDART00000137139
camk2g1
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr9_+_25776971 1.15 ENSDART00000146011
zeb2a
zinc finger E-box binding homeobox 2a
chr10_-_34916208 1.14 ENSDART00000187371
ccna1
cyclin A1
chr9_+_19529951 1.13 ENSDART00000125416
pknox1.1
pbx/knotted 1 homeobox 1.1
chr6_-_12275836 1.13 ENSDART00000189980
pkp4
plakophilin 4
chr24_+_19591893 1.13 ENSDART00000152026
slco5a1a
solute carrier organic anion transporter family member 5A1a
chr11_-_39044595 1.11 ENSDART00000065461
cldn19
claudin 19
chr7_-_26467404 1.08 ENSDART00000170859
mblac1
metallo-beta-lactamase domain containing 1
chr22_+_5176693 1.08 ENSDART00000160927
cers1
ceramide synthase 1
chr6_-_40713183 1.08 ENSDART00000157113
ENSDART00000154810
ENSDART00000153702
si:ch211-157b11.12
si:ch211-157b11.12
chr5_-_58112032 1.06 ENSDART00000016418
drd2b
dopamine receptor D2b
chr23_-_2901167 1.05 ENSDART00000165955
ENSDART00000190616
zhx3
zinc fingers and homeoboxes 3
chr11_+_5588122 1.04 ENSDART00000113281
zgc:172302
zgc:172302
chr10_+_33393829 1.04 ENSDART00000163458
ENSDART00000115379
zgc:153345
zgc:153345
chr4_-_9891874 1.01 ENSDART00000067193
adm2a
adrenomedullin 2a
chr6_-_40922971 0.99 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr10_+_36026576 0.99 ENSDART00000193786
hmgb1a
high mobility group box 1a
chr17_+_10593398 0.98 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mapkbp1
mitogen-activated protein kinase binding protein 1
chr17_+_3379673 0.97 ENSDART00000176354
sntg2
syntrophin, gamma 2
chr14_-_7207961 0.96 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b
chr14_-_33105434 0.96 ENSDART00000163795
dlg3
discs, large homolog 3 (Drosophila)
chr17_+_30545895 0.95 ENSDART00000076739
nhsl1a
NHS-like 1a
chr15_-_22074315 0.95 ENSDART00000149830
drd2a
dopamine receptor D2a
chr17_-_8570257 0.94 ENSDART00000154713
ENSDART00000121488
fzd3b
frizzled class receptor 3b
chr7_+_36898850 0.93 ENSDART00000113342
tox3
TOX high mobility group box family member 3
chr22_-_8725768 0.92 ENSDART00000189873
ENSDART00000181819
si:ch73-27e22.1
si:ch73-27e22.8
si:ch73-27e22.1
si:ch73-27e22.8
chr24_-_26399623 0.92 ENSDART00000112317
zgc:194621
zgc:194621
chr7_-_31759602 0.91 ENSDART00000113467
igdcc4
immunoglobulin superfamily, DCC subclass, member 4
chr6_-_51386656 0.90 ENSDART00000154732
ENSDART00000177990
ENSDART00000184928
ENSDART00000180197
ptprt
protein tyrosine phosphatase, receptor type, t
chr5_-_69004007 0.89 ENSDART00000137443
ank1a
ankyrin 1, erythrocytic a
chr16_+_23976227 0.88 ENSDART00000193013
apoc4
apolipoprotein C-IV
chr1_+_10318089 0.88 ENSDART00000029774
pip4p1b
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr12_-_14143344 0.88 ENSDART00000152742
buc2l
bucky ball 2-like
chr9_-_43538328 0.87 ENSDART00000140526
znf385b
zinc finger protein 385B
chr12_-_29233738 0.87 ENSDART00000153175
si:ch211-214e3.5
si:ch211-214e3.5
chr17_+_11675362 0.86 ENSDART00000157911
kif26ba
kinesin family member 26Ba

Network of associatons between targets according to the STRING database.

First level regulatory network of lhx6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.7 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.8 7.2 GO:0036306 embryonic heart tube elongation(GO:0036306)
1.8 16.0 GO:1902868 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
1.8 5.3 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.1 3.4 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
1.1 4.3 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
1.0 3.0 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.9 2.8 GO:2000434 regulation of protein neddylation(GO:2000434)
0.7 2.9 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.6 3.2 GO:0016322 neuron remodeling(GO:0016322)
0.6 1.8 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.6 3.0 GO:1901906 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.6 2.9 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.6 12.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.6 2.2 GO:0010543 regulation of platelet activation(GO:0010543) positive regulation of cell adhesion mediated by integrin(GO:0033630) regulation of platelet aggregation(GO:0090330)
0.5 3.8 GO:0072584 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.5 4.1 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.4 1.3 GO:1900182 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.4 1.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.4 4.4 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.4 3.7 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.4 1.8 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.3 1.4 GO:0051645 Golgi localization(GO:0051645)
0.3 2.4 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.3 2.6 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.3 5.6 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.2 4.1 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.2 0.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 1.2 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.2 1.1 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.2 0.7 GO:0034969 histone arginine methylation(GO:0034969)
0.2 3.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 1.7 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.2 4.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 1.9 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.2 1.2 GO:0021767 mammillary body development(GO:0021767)
0.2 3.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 1.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 1.1 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.2 3.5 GO:0050796 regulation of insulin secretion(GO:0050796)
0.2 0.5 GO:0097264 self proteolysis(GO:0097264)
0.2 1.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.2 5.7 GO:0007340 acrosome reaction(GO:0007340)
0.2 1.5 GO:0060114 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.2 1.1 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.2 3.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 1.7 GO:0019682 glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.1 0.6 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 1.5 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 5.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.7 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 1.4 GO:0098900 regulation of action potential(GO:0098900)
0.1 2.8 GO:0001556 oocyte maturation(GO:0001556)
0.1 2.6 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 1.4 GO:0001881 receptor recycling(GO:0001881)
0.1 5.1 GO:0006289 nucleotide-excision repair(GO:0006289)
0.1 2.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 2.6 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 1.0 GO:0033700 phospholipid efflux(GO:0033700)
0.1 4.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.3 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 2.2 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 5.1 GO:0046328 regulation of JNK cascade(GO:0046328)
0.1 2.7 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 2.1 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 1.6 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.1 1.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 1.2 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.5 GO:0060465 pharynx development(GO:0060465)
0.1 1.6 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.6 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 1.5 GO:0097352 autophagosome maturation(GO:0097352)
0.1 3.6 GO:0009060 aerobic respiration(GO:0009060)
0.1 0.5 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 2.9 GO:0036269 swimming behavior(GO:0036269)
0.1 1.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 3.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 1.0 GO:0009409 response to cold(GO:0009409)
0.1 1.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 3.0 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1 2.0 GO:0032355 response to estradiol(GO:0032355)
0.1 0.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 1.5 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.1 0.3 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 4.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 0.5 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.1 0.2 GO:0019532 oxalate transport(GO:0019532)
0.1 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.3 GO:0031116 positive regulation of microtubule polymerization or depolymerization(GO:0031112) positive regulation of microtubule polymerization(GO:0031116)
0.0 0.5 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.0 1.3 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 1.0 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 1.2 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 2.7 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.7 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 3.3 GO:0008360 regulation of cell shape(GO:0008360)
0.0 2.6 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 1.8 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 1.1 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.1 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 2.8 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 1.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.5 GO:0051225 spindle assembly(GO:0051225)
0.0 0.5 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.6 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.4 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.4 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.6 GO:0046847 filopodium assembly(GO:0046847)
0.0 9.2 GO:0006397 mRNA processing(GO:0006397)
0.0 0.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.7 GO:0030282 bone mineralization(GO:0030282)
0.0 5.5 GO:0099536 synaptic signaling(GO:0099536)
0.0 0.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.4 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 4.5 GO:0000003 reproduction(GO:0000003)
0.0 3.1 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.3 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.4 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.8 GO:0007030 Golgi organization(GO:0007030)
0.0 0.8 GO:0002181 cytoplasmic translation(GO:0002181)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 8.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.5 3.2 GO:0005955 calcineurin complex(GO:0005955)
0.5 3.2 GO:0043083 synaptic cleft(GO:0043083)
0.4 1.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.4 3.8 GO:0045171 intercellular bridge(GO:0045171)
0.4 1.5 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.4 3.7 GO:0098982 GABA-ergic synapse(GO:0098982)
0.3 1.8 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.3 2.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 2.4 GO:0044295 axonal growth cone(GO:0044295)
0.2 3.5 GO:0030667 secretory granule membrane(GO:0030667)
0.2 7.3 GO:0043204 perikaryon(GO:0043204)
0.2 4.4 GO:0035371 microtubule plus-end(GO:0035371)
0.2 1.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 1.4 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.1 6.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.0 GO:0035517 PR-DUB complex(GO:0035517)
0.1 1.0 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1 2.1 GO:0071564 npBAF complex(GO:0071564)
0.1 1.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 1.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 3.6 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.7 GO:0001650 fibrillar center(GO:0001650)
0.1 4.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 2.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.4 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.1 6.2 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 7.7 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 0.3 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 1.8 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.4 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 2.0 GO:0098978 glutamatergic synapse(GO:0098978)
0.1 5.1 GO:0005871 kinesin complex(GO:0005871)
0.1 0.5 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 1.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 3.4 GO:0005814 centriole(GO:0005814)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 2.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 7.5 GO:0043005 neuron projection(GO:0043005)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 6.7 GO:0030425 dendrite(GO:0030425)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 5.3 GO:0030424 axon(GO:0030424)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 12.9 GO:0045202 synapse(GO:0045202)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 3.4 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.6 GO:0016459 myosin complex(GO:0016459)
0.0 2.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.9 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 4.0 GO:0005730 nucleolus(GO:0005730)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 3.9 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.8 GO:0070469 respiratory chain(GO:0070469)
0.0 2.4 GO:0005813 centrosome(GO:0005813)
0.0 0.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 4.4 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 6.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.7 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
1.8 7.2 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
1.8 5.3 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
1.5 22.7 GO:0005504 fatty acid binding(GO:0005504)
1.4 4.1 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.9 2.6 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.6 3.0 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.5 3.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.5 2.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.5 1.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.4 1.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.4 1.7 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.3 7.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 6.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 2.0 GO:0045735 nutrient reservoir activity(GO:0045735)
0.3 3.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.3 1.3 GO:0050699 WW domain binding(GO:0050699)
0.2 2.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 0.7 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 3.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 4.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 0.7 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 2.5 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 1.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 1.0 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 3.7 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.2 1.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.2 1.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 0.7 GO:0030626 U12 snRNA binding(GO:0030626)
0.2 3.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 8.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 1.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.2 1.4 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 5.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 2.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 2.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.3 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.5 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.1 3.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 4.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.9 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 5.9 GO:0050661 NADP binding(GO:0050661)
0.1 2.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 3.1 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.7 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 3.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 2.1 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 1.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 4.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 5.5 GO:0016247 channel regulator activity(GO:0016247)
0.1 3.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 2.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.7 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.0 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.4 GO:0070888 E-box binding(GO:0070888)
0.1 0.6 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 1.3 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.5 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 3.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 3.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 10.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.6 GO:0044325 ion channel binding(GO:0044325)
0.0 2.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 2.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 2.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 9.0 GO:0008017 microtubule binding(GO:0008017)
0.0 0.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 2.9 GO:0019904 protein domain specific binding(GO:0019904)
0.0 6.6 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 1.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 2.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.6 GO:0060090 binding, bridging(GO:0060090)
0.0 1.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.0 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 2.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 1.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.7 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 2.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 2.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 3.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 1.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 2.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 5.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 2.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing