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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for lmx1ba+lmx1bb_lmx1al

Z-value: 0.57

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Transcription factors associated with lmx1ba+lmx1bb_lmx1al

Gene Symbol Gene ID Gene Info
lmx1bb
ENSDARG00000068365 LIM homeobox transcription factor 1, beta b
lmx1ba
ENSDARG00000104815 LIM homeobox transcription factor 1, beta a
lmx1al
ENSDARG00000077915 LIM homeobox transcription factor 1, alpha-like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lmx1aldr11_v1_chr3_+_52806347_52806441-0.279.2e-03Click!
lmx1bbdr11_v1_chr8_-_33381913_33381913-0.205.7e-02Click!
lmx1badr11_v1_chr5_-_5035683_50356830.113.0e-01Click!

Activity profile of lmx1ba+lmx1bb_lmx1al motif

Sorted Z-values of lmx1ba+lmx1bb_lmx1al motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_23431189 7.39 ENSDART00000004679
icn
ictacalcin
chr16_+_23961276 6.92 ENSDART00000192754
apoeb
apolipoprotein Eb
chr12_-_35830625 6.85 ENSDART00000180028
CU459056.1

chr20_-_40755614 6.22 ENSDART00000061247
cx32.3
connexin 32.3
chr22_+_19552987 6.11 ENSDART00000105315
hsd11b1la
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr16_+_29509133 5.41 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr25_-_3867990 5.19 ENSDART00000075663
cracr2b
calcium release activated channel regulator 2B
chr17_+_28103675 5.02 ENSDART00000188078
zgc:91908
zgc:91908
chr16_+_26777473 4.65 ENSDART00000188870
cdh17
cadherin 17, LI cadherin (liver-intestine)
chr7_+_25033924 4.31 ENSDART00000170873
sb:cb1058
sb:cb1058
chr10_+_21867307 3.89 ENSDART00000126629
cbln17
cerebellin 17
chr6_-_43283122 3.69 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr24_-_38110779 3.68 ENSDART00000147783
crp
c-reactive protein, pentraxin-related
chr2_+_33326522 3.59 ENSDART00000056655
klf17
Kruppel-like factor 17
chr3_-_15081874 3.57 ENSDART00000192532
nme4
NME/NM23 nucleoside diphosphate kinase 4
chr14_-_33481428 3.53 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr18_+_15644559 3.48 ENSDART00000061794
nr1h4
nuclear receptor subfamily 1, group H, member 4
chr2_+_20793982 3.47 ENSDART00000014785
prg4a
proteoglycan 4a
chr8_+_11425048 3.41 ENSDART00000018739
tjp2b
tight junction protein 2b (zona occludens 2)
chr7_+_20503344 3.39 ENSDART00000157699
si:dkey-19b23.12
si:dkey-19b23.12
chr13_-_31017960 3.36 ENSDART00000145287
wdfy4
WDFY family member 4
chr20_-_22476255 3.26 ENSDART00000103510
pdgfra
platelet-derived growth factor receptor, alpha polypeptide
chr8_+_6576940 3.14 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr24_-_35561672 3.11 ENSDART00000058564
mcm4
minichromosome maintenance complex component 4
chr11_-_45138857 2.92 ENSDART00000166501
cant1b
calcium activated nucleotidase 1b
chr15_+_36457888 2.90 ENSDART00000155100
si:dkey-262k9.2
si:dkey-262k9.2
chr6_+_41191482 2.90 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr19_-_13808630 2.85 ENSDART00000166895
ENSDART00000187670
ctgfb
connective tissue growth factor b
chr24_-_2450597 2.81 ENSDART00000188080
ENSDART00000093331
rreb1a
ras responsive element binding protein 1a
chr1_-_10071422 2.70 ENSDART00000135522
ENSDART00000033118
fga
fibrinogen alpha chain
chr16_+_33902006 2.68 ENSDART00000161807
ENSDART00000159474
gnl2
guanine nucleotide binding protein-like 2 (nucleolar)
chr1_+_44173245 2.67 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
ctnnd1
catenin (cadherin-associated protein), delta 1
chr17_-_24575893 2.65 ENSDART00000141914
aftphb
aftiphilin b
chr13_+_27232848 2.63 ENSDART00000138043
rin2
Ras and Rab interactor 2
chr15_-_21877726 2.63 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr19_+_43297546 2.54 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr13_+_25720969 2.48 ENSDART00000046050
pcbd1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr1_+_45056371 2.39 ENSDART00000073689
ENSDART00000167309
btr01
bloodthirsty-related gene family, member 1
chr6_+_40922572 2.33 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr3_+_27798094 2.32 ENSDART00000075100
ENSDART00000151437
carhsp1
calcium regulated heat stable protein 1
chr24_+_19415124 2.28 ENSDART00000186931
sulf1
sulfatase 1
chr22_-_15578402 2.26 ENSDART00000062986
hsh2d
hematopoietic SH2 domain containing
chr15_-_43284021 2.26 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr19_-_5699703 2.25 ENSDART00000082050
zgc:174904
zgc:174904
chr22_-_10121880 2.18 ENSDART00000002348
rdh5
retinol dehydrogenase 5 (11-cis/9-cis)
chr18_-_19456269 2.18 ENSDART00000060363
rpl4
ribosomal protein L4
chr23_-_31913069 2.15 ENSDART00000135526
mtfr2
mitochondrial fission regulator 2
chr1_-_10821584 2.14 ENSDART00000167452
ENSDART00000162137
crfb15
cytokine receptor family member B15
chr6_-_18228358 2.12 ENSDART00000167937
p4hb
prolyl 4-hydroxylase, beta polypeptide
chr22_+_1170294 2.11 ENSDART00000159761
ENSDART00000169809
irf6
interferon regulatory factor 6
chr18_+_3037998 2.10 ENSDART00000185844
ENSDART00000162657
rps3
ribosomal protein S3
chr21_+_25777425 2.06 ENSDART00000021620
cldnd
claudin d
chr13_+_28747934 2.05 ENSDART00000160176
ENSDART00000101633
ENSDART00000136318
prom2
prominin 2
chr23_+_39695827 2.03 ENSDART00000113893
ENSDART00000186679
tmco4
transmembrane and coiled-coil domains 4
chr17_+_16090436 2.03 ENSDART00000136059
ENSDART00000138734
znf395a
zinc finger protein 395a
chr14_+_33329420 2.01 ENSDART00000171090
ENSDART00000164062
sowahd
sosondowah ankyrin repeat domain family d
chr22_-_17653143 2.00 ENSDART00000089171
hmha1b
histocompatibility (minor) HA-1 b
chr17_-_41798856 1.98 ENSDART00000156031
ENSDART00000192801
ENSDART00000180172
ENSDART00000084745
ENSDART00000175577
ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr8_-_20230559 1.98 ENSDART00000193677
mllt1a
MLLT1, super elongation complex subunit a
chr20_-_23426339 1.97 ENSDART00000004625
zar1
zygote arrest 1
chr7_-_26306546 1.97 ENSDART00000140817
zgc:77439
zgc:77439
chr16_+_23913943 1.96 ENSDART00000175404
ENSDART00000129525
apoa4b.1
apolipoprotein A-IV b, tandem duplicate 1
chr18_+_7073130 1.89 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
si:dkey-88e18.2
chr17_-_21884323 1.88 ENSDART00000155574
cuzd1.1
CUB and zona pellucida-like domains 1, tandem duplicate 1
chr3_-_16719244 1.85 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr25_+_18475032 1.83 ENSDART00000073564
tes
testis derived transcript (3 LIM domains)
chr4_-_9891874 1.80 ENSDART00000067193
adm2a
adrenomedullin 2a
chr8_-_12867128 1.80 ENSDART00000142201
slc2a6
solute carrier family 2 (facilitated glucose transporter), member 6
chr16_-_29387215 1.79 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr10_-_21362071 1.70 ENSDART00000125167
avd
avidin
chr8_+_16758304 1.70 ENSDART00000133514
elovl7a
ELOVL fatty acid elongase 7a
chr11_+_37250839 1.69 ENSDART00000170209
il17rc
interleukin 17 receptor C
chr23_-_31913231 1.69 ENSDART00000146852
ENSDART00000085054
mtfr2
mitochondrial fission regulator 2
chr3_-_61162750 1.66 ENSDART00000055064
pvalb8
parvalbumin 8
chr1_+_9966384 1.64 ENSDART00000132607
si:dkeyp-75b4.8
si:dkeyp-75b4.8
chr5_+_36850650 1.63 ENSDART00000051186
nccrp1
non-specific cytotoxic cell receptor protein 1
chr13_-_31008275 1.59 ENSDART00000139394
wdfy4
WDFY family member 4
chr10_+_11261576 1.59 ENSDART00000155333
hsdl2
hydroxysteroid dehydrogenase like 2
chr6_+_3343834 1.56 ENSDART00000160290
st3gal3a
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr9_+_8396755 1.52 ENSDART00000043067
zgc:171776
zgc:171776
chr10_+_29850330 1.49 ENSDART00000168898
hspa8
heat shock protein 8
chr24_+_13316737 1.48 ENSDART00000191658
SBSPON
somatomedin B and thrombospondin type 1 domain containing
chr14_+_23717165 1.48 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr25_-_21031007 1.47 ENSDART00000138985
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr16_-_17347727 1.47 ENSDART00000144392
zyx
zyxin
chr2_-_26596794 1.45 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr10_-_15340362 1.45 ENSDART00000148119
ENSDART00000127277
ENSDART00000154037
ENSDART00000189109
pum3
pumilio RNA-binding family member 3
chr19_+_43119014 1.44 ENSDART00000023156
eef1a1l1
eukaryotic translation elongation factor 1 alpha 1, like 1
chr9_-_9415000 1.42 ENSDART00000146210
si:ch211-214p13.9
si:ch211-214p13.9
chr10_-_21362320 1.42 ENSDART00000189789
avd
avidin
chr20_+_46492175 1.42 ENSDART00000060695
zc3h14
zinc finger CCCH-type containing 14
chr1_-_16665044 1.41 ENSDART00000040434
asah1b
N-acylsphingosine amidohydrolase (acid ceramidase) 1b
chr18_-_6982499 1.41 ENSDART00000101525
si:dkey-266m15.6
si:dkey-266m15.6
chr13_+_24750078 1.40 ENSDART00000021053
col17a1b
collagen, type XVII, alpha 1b
chr11_-_38533505 1.39 ENSDART00000113894
slc45a3
solute carrier family 45, member 3
chr18_+_20560616 1.39 ENSDART00000136710
ENSDART00000151974
ENSDART00000121699
ENSDART00000040074
wee2
WEE1 homolog 2 (S. pombe)
chr14_+_35428152 1.39 ENSDART00000172597
sytl4
synaptotagmin-like 4
chr16_-_42056137 1.39 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr22_-_17652914 1.37 ENSDART00000138483
si:ch73-243b8.4
si:ch73-243b8.4
chr1_+_52392511 1.37 ENSDART00000144025
si:ch211-217k17.8
si:ch211-217k17.8
chr8_-_23612462 1.35 ENSDART00000025024
slc38a5b
solute carrier family 38, member 5b
chr8_-_12867434 1.35 ENSDART00000081657
slc2a6
solute carrier family 2 (facilitated glucose transporter), member 6
chr10_-_43771447 1.34 ENSDART00000052307
arrdc3b
arrestin domain containing 3b
chr10_+_8885769 1.31 ENSDART00000139466
itga2.2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2
chr20_-_52902693 1.30 ENSDART00000166115
ENSDART00000161050
ctsbb
cathepsin Bb
chr24_-_6078222 1.25 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr2_+_41526904 1.23 ENSDART00000127520
acvr1l
activin A receptor, type 1 like
chr7_+_56577522 1.22 ENSDART00000149130
ENSDART00000149624
hp
haptoglobin
chr21_-_35419486 1.19 ENSDART00000138529
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr5_+_6954162 1.19 ENSDART00000086666
stpg2
sperm-tail PG-rich repeat containing 2
chr17_+_25481466 1.18 ENSDART00000139451
aim1a
crystallin beta-gamma domain containing 1a
chr3_-_32337653 1.18 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
si:dkey-16p21.8
chr6_+_39098397 1.17 ENSDART00000003716
ENSDART00000188655
prss60.2
protease, serine, 60.2
chr19_+_30884960 1.16 ENSDART00000140603
ENSDART00000183224
ENSDART00000135484
ENSDART00000139599
yars
tyrosyl-tRNA synthetase
chr3_+_17537352 1.15 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr7_+_56577906 1.12 ENSDART00000184023
hp
haptoglobin
chr18_-_48550426 1.12 ENSDART00000145189
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr22_+_19220459 1.12 ENSDART00000163070
si:dkey-21e2.7
si:dkey-21e2.7
chr14_-_22113600 1.12 ENSDART00000113752
si:dkey-6i22.5
si:dkey-6i22.5
chr15_-_23376541 1.10 ENSDART00000078570
c1qtnf5
C1q and TNF related 5
chr24_-_40860603 1.09 ENSDART00000188032
CU633479.7

chr7_-_71389375 1.09 ENSDART00000128928
CABZ01074298.1

chr8_-_44378391 1.06 ENSDART00000158784
ENSDART00000098138
si:busm1-228j01.6
si:busm1-228j01.6
chr6_+_45918981 1.06 ENSDART00000149642
h6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr8_+_23152244 1.06 ENSDART00000036801
ENSDART00000184298
slc17a9a
solute carrier family 17 (vesicular nucleotide transporter), member 9a
chr24_-_30862168 1.05 ENSDART00000168540
ptbp2a
polypyrimidine tract binding protein 2a
chr5_+_33519943 1.04 ENSDART00000131316
ms4a17c.1
membrane-spanning 4-domains, subfamily A, member 17C.1
chr18_+_19456648 1.04 ENSDART00000079695
zwilch
zwilch kinetochore protein
chr18_+_2228737 1.01 ENSDART00000165301
rab27a
RAB27A, member RAS oncogene family
chr19_+_41464870 1.01 ENSDART00000102778
dlx6a
distal-less homeobox 6a
chr16_+_23087326 0.99 ENSDART00000167518
ENSDART00000161087
efna3b
ephrin-A3b
chr16_+_23303859 0.98 ENSDART00000006093
slc50a1
solute carrier family 50 (sugar efflux transporter), member 1
chr17_-_26867725 0.98 ENSDART00000153590
si:dkey-221l4.10
si:dkey-221l4.10
chr16_-_16761164 0.97 ENSDART00000135872
si:dkey-27n14.1
si:dkey-27n14.1
chr24_-_19719240 0.97 ENSDART00000135405
csrnp1b
cysteine-serine-rich nuclear protein 1b
chr11_+_35171406 0.96 ENSDART00000110839
mon1a
MON1 secretory trafficking family member A
chr20_-_37813863 0.96 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr8_-_20230802 0.94 ENSDART00000063400
mllt1a
MLLT1, super elongation complex subunit a
chr8_+_45334255 0.93 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr16_-_38609146 0.93 ENSDART00000144651
eif3ea
eukaryotic translation initiation factor 3, subunit E, a
chr1_-_43905252 0.93 ENSDART00000135477
ENSDART00000132089
si:dkey-22i16.3
si:dkey-22i16.3
chr2_+_36112273 0.92 ENSDART00000191315
traj35
T-cell receptor alpha joining 35
chr19_+_30884706 0.91 ENSDART00000052126
yars
tyrosyl-tRNA synthetase
chr23_+_31913292 0.91 ENSDART00000136910
armc1l
armadillo repeat containing 1, like
chr24_-_27452488 0.90 ENSDART00000136433
ccl34b.8
chemokine (C-C motif) ligand 34b, duplicate 8
chr3_+_46635527 0.89 ENSDART00000153971
si:dkey-248g21.1
si:dkey-248g21.1
chr3_+_1015867 0.89 ENSDART00000109912
si:ch1073-464p5.5
si:ch1073-464p5.5
chr1_+_52929185 0.88 ENSDART00000147683
inpp4b
inositol polyphosphate-4-phosphatase type II B
chr3_+_17933132 0.86 ENSDART00000104299
ENSDART00000162144
ENSDART00000162242
ENSDART00000166289
ENSDART00000171101
ENSDART00000164853
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr9_+_24008879 0.85 ENSDART00000190419
ENSDART00000191843
ENSDART00000148226
mlphb
melanophilin b
chr11_-_41853874 0.85 ENSDART00000002556
mrto4
MRT4 homolog, ribosome maturation factor
chr21_+_5580948 0.85 ENSDART00000160373
ly6m7
lymphocyte antigen 6 family member M7
chr5_+_66433287 0.83 ENSDART00000170757
kntc1
kinetochore associated 1
chr2_+_19522082 0.82 ENSDART00000146098
pimr49
Pim proto-oncogene, serine/threonine kinase, related 49
chr8_-_37249813 0.82 ENSDART00000098634
ENSDART00000140233
ENSDART00000061328
rbm39b
RNA binding motif protein 39b
chr10_+_25726694 0.82 ENSDART00000140308
ugt5d1
UDP glucuronosyltransferase 5 family, polypeptide D1
chr2_-_55298075 0.82 ENSDART00000186404
ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr3_-_21094437 0.81 ENSDART00000153739
ENSDART00000109790
nlk1
nemo-like kinase, type 1
chr15_-_20400423 0.81 ENSDART00000081290
ENSDART00000156813
ENSDART00000192427
rnaset2l
ribonuclease T2, like
chr8_-_25034411 0.80 ENSDART00000135973
nfyal
nuclear transcription factor Y, alpha, like
chr6_-_16717878 0.80 ENSDART00000153552
nomo
nodal modulator
chr2_+_29842878 0.79 ENSDART00000131376
si:ch211-207d6.2
si:ch211-207d6.2
chr24_-_4450238 0.79 ENSDART00000066835
fzd8a
frizzled class receptor 8a
chr24_+_16985181 0.79 ENSDART00000135580
eif2s3
eukaryotic translation initiation factor 2, subunit 3 gamma
chr13_+_35339182 0.77 ENSDART00000019323
jag1b
jagged 1b
chr2_+_36721357 0.77 ENSDART00000019063
pdcd10b
programmed cell death 10b
chr20_-_43663494 0.76 ENSDART00000144564
BX470188.1

chr6_-_20952187 0.76 ENSDART00000074327
igfbp2a
insulin-like growth factor binding protein 2a
chr1_-_18811517 0.76 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr23_-_24394719 0.75 ENSDART00000044918
epha2b
eph receptor A2 b
chr25_-_18435481 0.75 ENSDART00000004771
poc1b
POC1 centriolar protein B
chr10_-_26512993 0.75 ENSDART00000188549
ENSDART00000193316
si:dkey-5g14.1
si:dkey-5g14.1
chr3_-_13921173 0.74 ENSDART00000159177
ENSDART00000165174
si:dkey-61n16.5
si:dkey-61n16.5
chr12_+_47698356 0.74 ENSDART00000112010
lzts2b
leucine zipper, putative tumor suppressor 2b
chr21_+_42717424 0.74 ENSDART00000166936
ENSDART00000172135
sh3pxd2b
SH3 and PX domains 2B
chr5_-_69620722 0.73 ENSDART00000097248
aldh2.2
aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 2
chr16_-_29528198 0.73 ENSDART00000150028
onecutl
one cut domain, family member, like
chr16_-_51299061 0.72 ENSDART00000148677
serpinb1l4
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4
chr10_+_6884627 0.71 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr6_+_3280939 0.71 ENSDART00000151359
kdm4aa
lysine (K)-specific demethylase 4A, genome duplicate a
chr9_+_50001746 0.71 ENSDART00000058892
slc38a11
solute carrier family 38, member 11
chr5_+_35786141 0.71 ENSDART00000022043
ENSDART00000127383
stard8
StAR-related lipid transfer (START) domain containing 8
chr2_-_37140423 0.70 ENSDART00000144220
tspan37
tetraspanin 37
chr1_-_5455498 0.70 ENSDART00000040368
ENSDART00000114035
mnx2b
motor neuron and pancreas homeobox 2b
chr8_-_14126646 0.66 ENSDART00000027225
bgna
biglycan a
chr9_+_34641237 0.66 ENSDART00000133996
shox
short stature homeobox
chr8_+_25034544 0.66 ENSDART00000123300
ngrn
neugrin, neurite outgrowth associated
chr13_-_45155792 0.65 ENSDART00000163556
runx3
runt-related transcription factor 3
chr2_-_38363017 0.65 ENSDART00000088026
prmt5
protein arginine methyltransferase 5
chr20_-_6532462 0.65 ENSDART00000054653
mcm3l
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like
chr10_-_25217347 0.64 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr9_+_37329036 0.64 ENSDART00000131756
slc15a2
solute carrier family 15 (oligopeptide transporter), member 2
chr10_+_7593185 0.64 ENSDART00000162617
ENSDART00000162590
ENSDART00000171744
ppp2cb
protein phosphatase 2, catalytic subunit, beta isozyme
chr3_+_17933553 0.64 ENSDART00000167731
ENSDART00000165644
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr1_-_26444075 0.64 ENSDART00000125690
ints12
integrator complex subunit 12
chr11_+_18873619 0.63 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr5_-_7199998 0.62 ENSDART00000167316
CABZ01087502.1

chr24_-_40744672 0.62 ENSDART00000160672
CU633479.1

chr12_+_16168342 0.61 ENSDART00000079326
ENSDART00000170024
lrp2b
low density lipoprotein receptor-related protein 2b
chr5_+_25733774 0.58 ENSDART00000137088
ENSDART00000098467
abhd17b
abhydrolase domain containing 17B

Network of associatons between targets according to the STRING database.

First level regulatory network of lmx1ba+lmx1bb_lmx1al

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
1.2 3.6 GO:0048785 hatching gland development(GO:0048785)
0.7 3.3 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.6 2.4 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.5 3.8 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.5 2.6 GO:0034380 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873) high-density lipoprotein particle assembly(GO:0034380)
0.5 1.4 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.5 1.4 GO:0097264 self proteolysis(GO:0097264)
0.5 1.9 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.4 1.3 GO:0060631 regulation of meiosis I(GO:0060631)
0.4 2.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4 2.4 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.3 1.4 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.3 3.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.3 1.2 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.3 1.2 GO:0042755 eating behavior(GO:0042755)
0.3 2.3 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.3 0.8 GO:0060898 spinal cord radial glial cell differentiation(GO:0021531) eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.3 0.8 GO:1903358 regulation of Golgi organization(GO:1903358)
0.2 2.5 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 1.5 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.2 3.6 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.2 3.5 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.2 0.8 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.2 0.8 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.2 0.6 GO:0034969 histone arginine methylation(GO:0034969)
0.2 0.8 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 3.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.4 GO:0072111 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.1 2.7 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 2.0 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.4 GO:0097065 anterior head development(GO:0097065)
0.1 0.7 GO:0071800 podosome assembly(GO:0071800)
0.1 1.0 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.1 2.1 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.1 0.7 GO:0051013 microtubule severing(GO:0051013)
0.1 0.5 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.6 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
0.1 0.4 GO:0015871 choline transport(GO:0015871)
0.1 1.1 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.3 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.1 1.4 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 1.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 2.2 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 0.8 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.1 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 1.4 GO:0008354 germ cell migration(GO:0008354)
0.1 1.6 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.6 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.3 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 1.0 GO:0031641 regulation of myelination(GO:0031641)
0.1 0.4 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 1.4 GO:0030183 B cell differentiation(GO:0030183)
0.1 1.0 GO:0035141 medial fin morphogenesis(GO:0035141)
0.1 0.7 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.3 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.1 2.3 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 0.9 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.1 0.4 GO:0070265 necrotic cell death(GO:0070265) programmed necrotic cell death(GO:0097300)
0.1 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 2.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.6 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.8 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.5 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.6 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.7 GO:0042493 response to drug(GO:0042493)
0.0 4.3 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 2.0 GO:0009060 aerobic respiration(GO:0009060)
0.0 1.0 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 3.4 GO:0003341 cilium movement(GO:0003341)
0.0 3.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.9 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.3 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.2 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 2.8 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.4 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 1.0 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.2 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 2.4 GO:0036293 response to hypoxia(GO:0001666) response to decreased oxygen levels(GO:0036293)
0.0 0.7 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.5 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 2.4 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 2.6 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
0.0 0.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 4.3 GO:0048793 pronephros development(GO:0048793)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 1.0 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.5 GO:0019319 hexose biosynthetic process(GO:0019319)
0.0 0.1 GO:0097435 fibril organization(GO:0097435)
0.0 1.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 1.5 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 0.4 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 1.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 7.2 GO:0051603 proteolysis involved in cellular protein catabolic process(GO:0051603)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 2.6 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.5 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.0 0.1 GO:0060021 palate development(GO:0060021)
0.0 0.7 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.4 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 1.5 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.0 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839) negative regulation of nuclear division(GO:0051784)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:0060968 regulation of gene silencing(GO:0060968)
0.0 0.0 GO:0009080 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.9 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.2 3.5 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.9 2.7 GO:0005577 fibrinogen complex(GO:0005577)
0.4 2.6 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.4 1.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 1.4 GO:0019815 B cell receptor complex(GO:0019815)
0.3 1.0 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.3 1.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.3 0.8 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.3 2.1 GO:0071914 prominosome(GO:0071914)
0.3 0.8 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.2 1.2 GO:0070724 BMP receptor complex(GO:0070724)
0.2 2.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 3.8 GO:0042555 MCM complex(GO:0042555)
0.2 0.9 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.2 0.5 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.2 0.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.4 GO:0097189 apoptotic body(GO:0097189)
0.1 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 9.9 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 3.8 GO:0016342 catenin complex(GO:0016342)
0.1 0.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 2.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.7 GO:0002102 podosome(GO:0002102)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 12.8 GO:0000323 lytic vacuole(GO:0000323)
0.0 2.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.4 GO:0043186 P granule(GO:0043186)
0.0 0.4 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 2.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.1 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 1.3 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 3.3 GO:0005925 focal adhesion(GO:0005925)
0.0 1.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.1 GO:0030496 midbody(GO:0030496)
0.0 0.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 5.6 GO:0005730 nucleolus(GO:0005730)
0.0 2.0 GO:0016607 nuclear speck(GO:0016607)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.6 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 1.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.0 GO:0005795 Golgi stack(GO:0005795)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.8 3.3 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.6 3.1 GO:0009374 biotin binding(GO:0009374)
0.6 3.5 GO:0032052 bile acid binding(GO:0032052)
0.5 2.6 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.5 1.5 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.4 3.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.4 1.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.4 1.4 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.3 9.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.3 1.5 GO:0050699 WW domain binding(GO:0050699)
0.3 0.8 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.2 1.6 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.2 2.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.6 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 6.1 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.2 1.4 GO:0015157 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 1.9 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2 2.1 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 3.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 2.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 3.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 3.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 3.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 5.7 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 2.3 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 1.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.6 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.1 0.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 1.0 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
0.1 0.7 GO:0016176 superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.4 GO:0032190 acrosin binding(GO:0032190)
0.1 1.7 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.8 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 1.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.2 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.3 GO:0043295 glutathione binding(GO:0043295)
0.1 0.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 5.4 GO:0045296 cadherin binding(GO:0045296)
0.1 1.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.9 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1 0.7 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 4.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024) transforming growth factor beta binding(GO:0050431)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 5.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.3 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.4 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.0 0.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 3.4 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 2.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 3.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 2.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 3.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.4 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.6 GO:0017022 myosin binding(GO:0017022)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 1.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.6 GO:0051020 GTPase binding(GO:0051020)
0.0 0.2 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 6.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 2.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 2.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 2.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.3 GO:0042802 identical protein binding(GO:0042802)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0042562 hormone binding(GO:0042562)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.0 GO:0003884 D-amino-acid oxidase activity(GO:0003884)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 3.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 2.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 3.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 2.3 PID CONE PATHWAY Visual signal transduction: Cones
0.1 3.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 1.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 0.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 3.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 3.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 2.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID P73PATHWAY p73 transcription factor network
0.0 1.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.3 3.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 3.9 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 3.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 2.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 3.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 1.9 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 2.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 0.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 0.9 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 3.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 2.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 3.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+