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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for mafk

Z-value: 1.19

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Transcription factors associated with mafk

Gene Symbol Gene ID Gene Info
mafk
ENSDARG00000100947 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mafkdr11_v1_chr3_-_42981739_42981739-0.179.6e-02Click!

Activity profile of mafk motif

Sorted Z-values of mafk motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_32818607 18.58 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr22_-_13857729 14.90 ENSDART00000177971
s100b
S100 calcium binding protein, beta (neural)
chr12_-_4683325 13.47 ENSDART00000152771
si:ch211-255p10.3
si:ch211-255p10.3
chr23_-_29376859 13.03 ENSDART00000146411
sst6
somatostatin 6
chr16_-_16182319 12.46 ENSDART00000103815
stmn2a
stathmin 2a
chr15_+_37559570 12.09 ENSDART00000085522
hspb6
heat shock protein, alpha-crystallin-related, b6
chr23_-_15878879 12.08 ENSDART00000010119
eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr22_-_26595027 11.98 ENSDART00000184162
CABZ01072309.1

chr7_+_39386982 11.40 ENSDART00000146702
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr2_-_2020044 10.65 ENSDART00000024135
tubb2
tubulin, beta 2A class IIa
chr19_+_31771270 9.94 ENSDART00000147474
stmn2b
stathmin 2b
chr2_+_9821757 9.87 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
anxa13l
annexin A13, like
chr16_-_43026273 9.65 ENSDART00000156820
ENSDART00000189080
si:dkey-7j14.5
si:dkey-7j14.5
chr20_-_39271844 9.09 ENSDART00000192708
clu
clusterin
chr1_-_46989650 8.87 ENSDART00000129072
ENSDART00000150507
si:dkey-22n8.3
si:dkey-22n8.3
chr2_+_25278107 8.50 ENSDART00000131977
ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr20_-_47347962 8.41 ENSDART00000080863
dtnba
dystrobrevin, beta a
chr20_-_47348116 8.33 ENSDART00000162087
ENSDART00000160769
ENSDART00000164484
dtnba
dystrobrevin, beta a
chr23_-_27571667 8.05 ENSDART00000008174
pfkma
phosphofructokinase, muscle a
chr2_+_9822319 8.01 ENSDART00000144078
ENSDART00000144371
anxa13l
annexin A13, like
chr1_-_1894722 7.85 ENSDART00000165669
si:ch211-132g1.3
si:ch211-132g1.3
chr2_+_9552456 7.64 ENSDART00000056896
dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr17_-_12389259 7.43 ENSDART00000185724
snap25b
synaptosomal-associated protein, 25b
chr21_+_20383837 7.42 ENSDART00000026430
hspb11
heat shock protein, alpha-crystallin-related, b11
chr20_-_31905968 7.32 ENSDART00000142806
stxbp5a
syntaxin binding protein 5a (tomosyn)
chr23_-_35756115 7.30 ENSDART00000043429
jph2
junctophilin 2
chr14_-_17588345 7.19 ENSDART00000143486
selenot2
selenoprotein T, 2
chr6_-_47246948 7.14 ENSDART00000162435
grm4
glutamate receptor, metabotropic 4
chr24_-_29868151 7.13 ENSDART00000184802
aglb
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b
chr11_-_18253111 7.03 ENSDART00000125984
mustn1b
musculoskeletal, embryonic nuclear protein 1b
chr8_+_24861264 6.91 ENSDART00000099607
slc6a17
solute carrier family 6 (neutral amino acid transporter), member 17
chr13_+_35746440 6.79 ENSDART00000187859
gpr75
G protein-coupled receptor 75
chr19_+_30990129 6.45 ENSDART00000052169
ENSDART00000193376
sync
syncoilin, intermediate filament protein
chr24_-_40731305 6.42 ENSDART00000172073
CU633479.6

chr7_+_69841017 6.33 ENSDART00000169107
FO818704.1

chr13_-_226393 6.29 ENSDART00000172677
rtn4b
reticulon 4b
chr12_+_48216662 6.09 ENSDART00000187369
lrrc20
leucine rich repeat containing 20
chr13_-_226109 6.06 ENSDART00000161705
ENSDART00000172744
ENSDART00000163902
ENSDART00000158208
rtn4b
reticulon 4b
chr16_-_27640995 6.06 ENSDART00000019658
nacad
NAC alpha domain containing
chr6_+_40723554 6.01 ENSDART00000103833
slc26a6l
solute carrier family 26, member 6, like
chr4_+_6572364 5.96 ENSDART00000122574
ppp1r3aa
protein phosphatase 1, regulatory subunit 3Aa
chr23_+_13814978 5.95 ENSDART00000090864
lmod3
leiomodin 3 (fetal)
chr21_-_23110841 5.94 ENSDART00000147896
ENSDART00000003076
ENSDART00000184925
ENSDART00000190386
usp28
ubiquitin specific peptidase 28
chr7_-_52842605 5.83 ENSDART00000083002
map1aa
microtubule-associated protein 1Aa
chr24_+_41940299 5.74 ENSDART00000022349
epb41l3a
erythrocyte membrane protein band 4.1-like 3a
chr16_-_43025885 5.70 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
si:dkey-7j14.5
chr3_-_21280373 5.68 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr1_-_25966068 5.67 ENSDART00000137869
ENSDART00000134192
synpo2b
synaptopodin 2b
chr9_-_12034444 5.40 ENSDART00000038651
znf804a
zinc finger protein 804A
chr10_+_4235998 5.29 ENSDART00000169328
plppr1
phospholipid phosphatase related 1
chr1_-_25966411 5.27 ENSDART00000193375
synpo2b
synaptopodin 2b
chr21_-_11820379 5.24 ENSDART00000126640
RHOBTB3
si:dkey-6b12.5
chr19_-_6385594 5.19 ENSDART00000104950
atp1a3a
ATPase Na+/K+ transporting subunit alpha 3a
chr5_+_66355153 5.08 ENSDART00000082745
si:ch211-261c8.5
si:ch211-261c8.5
chr22_-_31059670 4.98 ENSDART00000022445
cand2
cullin-associated and neddylation-dissociated 2 (putative)
chr22_-_4760187 4.90 ENSDART00000081969
rad23ab
RAD23 homolog A, nucleotide excision repair protein b
chr5_-_71460556 4.88 ENSDART00000108804
brinp1
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr14_+_34780886 4.86 ENSDART00000130469
ENSDART00000188806
ENSDART00000172924
ENSDART00000173266
ENSDART00000166377
ENSDART00000173371
sh3tc2
SH3 domain and tetratricopeptide repeats 2
chr16_+_14033121 4.84 ENSDART00000135844
rusc1
RUN and SH3 domain containing 1
chr19_-_32641725 4.83 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr20_+_18661624 4.78 ENSDART00000152136
ENSDART00000126959
tnfaip2a
tumor necrosis factor, alpha-induced protein 2a
chr4_-_9728730 4.77 ENSDART00000150265
mical3b
microtubule associated monooxygenase, calponin and LIM domain containing 3b
chr21_-_31143903 4.68 ENSDART00000111571
rap1gap2b
RAP1 GTPase activating protein 2b
chr7_-_52842007 4.58 ENSDART00000182710
map1aa
microtubule-associated protein 1Aa
chr6_+_41463786 4.52 ENSDART00000065006
twf2a
twinfilin actin-binding protein 2a
chr14_-_30490763 4.47 ENSDART00000193166
ENSDART00000183471
ENSDART00000087859
micu3b
mitochondrial calcium uptake family, member 3b
chr7_+_17992455 4.46 ENSDART00000089211
ENSDART00000190881
ehbp1l1a
EH domain binding protein 1-like 1a
chr19_+_30990815 4.42 ENSDART00000134645
sync
syncoilin, intermediate filament protein
chr18_+_1703984 4.41 ENSDART00000114010
slitrk3a
SLIT and NTRK-like family, member 3a
chr13_-_11644806 4.37 ENSDART00000169953
dctn1b
dynactin 1b
chr23_-_19500559 4.36 ENSDART00000177414
ENSDART00000145898
asb14b
ankyrin repeat and SOCS box containing 14b
chr25_+_16945348 4.36 ENSDART00000016591
fgf6a
fibroblast growth factor 6a
chr14_-_30960470 4.20 ENSDART00000129989
si:ch211-191o15.6
si:ch211-191o15.6
chr23_-_18286822 4.17 ENSDART00000136672
fam19a1a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1a
chr24_+_24923166 4.17 ENSDART00000065288
pcyt1ba
phosphate cytidylyltransferase 1, choline, beta a
chr8_-_34052019 4.16 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pbx3b
pre-B-cell leukemia homeobox 3b
chr11_-_10770053 4.03 ENSDART00000179213
slc4a10a
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr4_-_5291256 3.98 ENSDART00000150864
SNAP91 (1 of many)
si:ch211-214j24.9
chr13_-_23007813 3.97 ENSDART00000057638
hk1
hexokinase 1
chr22_-_16416882 3.93 ENSDART00000062749
cts12
cathepsin 12
chr14_-_30490465 3.90 ENSDART00000173107
micu3b
mitochondrial calcium uptake family, member 3b
chr2_-_9544161 3.90 ENSDART00000124425
slc25a24l
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24, like
chr1_+_51039558 3.89 ENSDART00000024743
dpy30
dpy-30 histone methyltransferase complex regulatory subunit
chr25_-_16782394 3.87 ENSDART00000019413
ndufa9a
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9a
chr7_+_20475788 3.76 ENSDART00000171155
si:dkey-19b23.13
si:dkey-19b23.13
chr16_+_13855039 3.75 ENSDART00000113764
ENSDART00000143983
zgc:174888
zgc:174888
chr7_+_63325819 3.74 ENSDART00000085612
ENSDART00000161436
pcdh7b
protocadherin 7b
chr25_-_16818978 3.73 ENSDART00000104140
dyrk4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr10_+_466926 3.65 ENSDART00000145220
arvcfa
ARVCF, delta catenin family member a
chr20_-_19422496 3.64 ENSDART00000143658
si:ch211-278j3.3
si:ch211-278j3.3
chr2_-_16562505 3.64 ENSDART00000156406
atp1b3a
ATPase Na+/K+ transporting subunit beta 3a
chr6_+_12853655 3.52 ENSDART00000156341
fam117ba
family with sequence similarity 117, member Ba
chr13_-_40499296 3.52 ENSDART00000158338
CNNM1
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr16_+_14029283 3.46 ENSDART00000146165
ENSDART00000132075
rusc1
RUN and SH3 domain containing 1
chr1_-_53750522 3.46 ENSDART00000190755
akt3b
v-akt murine thymoma viral oncogene homolog 3b
chr6_-_14292307 3.42 ENSDART00000177852
ENSDART00000061745
inpp4ab
inositol polyphosphate-4-phosphatase type I Ab
chr24_+_26039464 3.39 ENSDART00000131017
tnk2a
tyrosine kinase, non-receptor, 2a
chr5_-_37935607 3.38 ENSDART00000141233
ENSDART00000084868
ENSDART00000125857
scn4bb
sodium channel, voltage-gated, type IV, beta b
chr5_+_42912966 3.35 ENSDART00000039973
rufy3
RUN and FYVE domain containing 3
chr7_+_17992640 3.29 ENSDART00000173679
ehbp1l1a
EH domain binding protein 1-like 1a
chr4_+_33012407 3.27 ENSDART00000151873
si:dkey-26h11.2
si:dkey-26h11.2
chr10_-_7974155 3.27 ENSDART00000147368
ENSDART00000075524
osbp2
oxysterol binding protein 2
chr19_-_10243148 3.26 ENSDART00000148073
shisa7b
shisa family member 7
chr1_+_49266886 3.26 ENSDART00000137179
caly
calcyon neuron-specific vesicular protein
chr9_+_34380299 3.18 ENSDART00000131705
lamp1
lysosomal-associated membrane protein 1
chr6_-_35446110 3.14 ENSDART00000058773
rgs16
regulator of G protein signaling 16
chr12_+_1455147 3.12 ENSDART00000018752
cops3
COP9 signalosome subunit 3
chr23_+_36118738 3.11 ENSDART00000139319
hoxc5a
homeobox C5a
chr21_-_929293 3.10 ENSDART00000006419
txnl1
thioredoxin-like 1
chr19_-_41404870 3.10 ENSDART00000167772
sem1
SEM1, 26S proteasome complex subunit
chr13_-_37642890 3.01 ENSDART00000146483
ENSDART00000136071
ENSDART00000111786
si:dkey-188i13.9
si:dkey-188i13.9
chr18_-_14937211 2.97 ENSDART00000141893
mlc1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr25_+_10485103 2.95 ENSDART00000104576
psmd13
proteasome 26S subunit, non-ATPase 13
chr12_-_19862912 2.92 ENSDART00000145788
shisa9a
shisa family member 9a
chr19_-_6873107 2.92 ENSDART00000124440
CABZ01029822.1

chr8_-_30779101 2.92 ENSDART00000062229
p2rx7
purinergic receptor P2X, ligand-gated ion channel, 7
chr7_-_50917255 2.90 ENSDART00000022918
ankrd46b
ankyrin repeat domain 46b
chr19_+_31404686 2.89 ENSDART00000078459
pip4p2
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
chr7_-_62003831 2.87 ENSDART00000113585
ENSDART00000062704
plaa
phospholipase A2-activating protein
chr22_-_13350240 2.86 ENSDART00000154095
ENSDART00000155118
si:ch211-227m13.1
si:ch211-227m13.1
chr14_+_24840669 2.83 ENSDART00000106039
arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr5_-_19052184 2.82 ENSDART00000133330
fam214b
family with sequence similarity 214, member B
chr3_-_21061931 2.81 ENSDART00000036741
fam57ba
family with sequence similarity 57, member Ba
chr18_-_5692292 2.78 ENSDART00000121503
cplx3b
complexin 3b
chr3_+_31177972 2.77 ENSDART00000185954
clec19a
C-type lectin domain containing 19A
chr5_+_28398449 2.75 ENSDART00000165292
nsmfb
NMDA receptor synaptonuclear signaling and neuronal migration factor b
chr5_+_36614196 2.74 ENSDART00000150574
nova1
neuro-oncological ventral antigen 1
chr11_+_2198831 2.72 ENSDART00000160515
hoxc6b
homeobox C6b
chr13_+_23162447 2.70 ENSDART00000180209
sorbs1
sorbin and SH3 domain containing 1
chr6_+_21395051 2.70 ENSDART00000017774
cacng5a
calcium channel, voltage-dependent, gamma subunit 5a
chr23_+_23182037 2.69 ENSDART00000137353
klhl17
kelch-like family member 17
chr5_-_21030934 2.69 ENSDART00000133461
ENSDART00000098667
camk2b1
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr19_+_8144556 2.66 ENSDART00000027274
ENSDART00000147218
efna3a
ephrin-A3a
chr10_-_4316015 2.61 ENSDART00000109916
ENSDART00000180867
grin3a
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
chr10_+_2684958 2.60 ENSDART00000112019
setd9
SET domain containing 9
chr10_+_15608326 2.60 ENSDART00000188770
zfand5b
zinc finger, AN1-type domain 5b
chr24_+_12983434 2.57 ENSDART00000145214
ENSDART00000146911
ENSDART00000066700
eloca
elongin C paralog a
chr25_-_35045250 2.55 ENSDART00000156508
ENSDART00000126590
zgc:114046
zgc:114046
chr16_+_9779680 2.51 ENSDART00000154253
zgc:92912
zgc:92912
chr23_+_23183449 2.50 ENSDART00000132296
klhl17
kelch-like family member 17
chr14_-_30932373 2.47 ENSDART00000172988
si:zfos-80g12.1
si:zfos-80g12.1
chr14_-_34771371 2.42 ENSDART00000160598
ENSDART00000150413
ENSDART00000168910
ablim3
actin binding LIM protein family, member 3
chr5_-_16996482 2.42 ENSDART00000144501
galnt9
polypeptide N-acetylgalactosaminyltransferase 9
chr17_-_45247151 2.39 ENSDART00000186230
ttbk2a
tau tubulin kinase 2a
chr1_+_51312752 2.38 ENSDART00000063938
mast1a
microtubule associated serine/threonine kinase 1a
chr7_-_40630698 2.37 ENSDART00000134547
ube3c
ubiquitin protein ligase E3C
chr8_-_34051548 2.37 ENSDART00000105204
pbx3b
pre-B-cell leukemia homeobox 3b
chr5_-_31928913 2.36 ENSDART00000142919
ssh1b
slingshot protein phosphatase 1b
chr2_-_31800521 2.35 ENSDART00000112763
retreg1
reticulophagy regulator 1
chr17_-_8169774 2.33 ENSDART00000091828
syne1b
spectrin repeat containing, nuclear envelope 1b
chr11_+_45300669 2.33 ENSDART00000172238
mafgb
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
chr1_-_40227166 2.30 ENSDART00000146680
si:ch211-113e8.3
si:ch211-113e8.3
chr9_-_23118350 2.27 ENSDART00000020884
lypd6
LY6/PLAUR domain containing 6
chr16_-_9869056 2.27 ENSDART00000149312
ncalda
neurocalcin delta a
chr8_-_13999293 2.25 ENSDART00000142098
si:dkeyp-110g5.4
si:dkeyp-110g5.4
chr18_+_34478959 2.25 ENSDART00000059394
kcnab1a
potassium voltage-gated channel, shaker-related subfamily, beta member 1 a
chr11_+_13630107 2.24 ENSDART00000172220
si:ch211-1a19.3
si:ch211-1a19.3
chr21_-_929448 2.24 ENSDART00000133976
txnl1
thioredoxin-like 1
chr13_+_2617555 2.21 ENSDART00000162208
plpp4
phospholipid phosphatase 4
chr14_+_30279391 2.15 ENSDART00000172794
fgl1
fibrinogen-like 1
chr17_-_12966907 2.15 ENSDART00000022874
psma6a
proteasome subunit alpha 6a
chr10_-_74408 2.15 ENSDART00000100073
ENSDART00000141723
dyrk1aa
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a
chr2_+_19236677 2.13 ENSDART00000166292
cc2d1b
coiled-coil and C2 domain containing 1B
chr15_-_16679517 2.13 ENSDART00000177384
caln1
calneuron 1
chr22_-_11724563 2.13 ENSDART00000190796
ENSDART00000184744
krt222
keratin 222
chr22_+_28446557 2.09 ENSDART00000089546
abi3bpb
ABI family, member 3 (NESH) binding protein b
chr17_-_22067451 2.08 ENSDART00000156872
ttbk1b
tau tubulin kinase 1b
chr5_-_62940851 2.08 ENSDART00000137052
specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr21_+_9576176 2.08 ENSDART00000161289
ENSDART00000159899
ENSDART00000162834
mapk10
mitogen-activated protein kinase 10
chr10_+_29963518 2.05 ENSDART00000011317
ENSDART00000099964
ENSDART00000182990
ENSDART00000113912
ntm
neurotrimin
chr20_-_39103119 2.05 ENSDART00000143379
rcan2
regulator of calcineurin 2
chr18_+_31410652 2.05 ENSDART00000098504
def8
differentially expressed in FDCP 8 homolog (mouse)
chr11_-_3334248 2.05 ENSDART00000154314
ENSDART00000121861
prph
peripherin
chr11_+_13629528 2.04 ENSDART00000186509
si:ch211-1a19.3
si:ch211-1a19.3
chr4_+_76926059 2.03 ENSDART00000136192
si:dkey-240n22.6
si:dkey-240n22.6
chr13_+_1430094 2.03 ENSDART00000169888
si:ch211-165e15.1
si:ch211-165e15.1
chr17_+_22311413 2.02 ENSDART00000151929
slc8a1b
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr8_-_17516448 2.00 ENSDART00000100667
skia
v-ski avian sarcoma viral oncogene homolog a
chr3_+_7617353 1.97 ENSDART00000165551
zgc:109949
zgc:109949
chr11_+_45255774 1.97 ENSDART00000172838
aspscr1
alveolar soft part sarcoma chromosome region, candidate 1
chr1_+_41690402 1.96 ENSDART00000177298
fbxo41
F-box protein 41
chr2_-_24962002 1.95 ENSDART00000132050
hltf
helicase-like transcription factor
chr1_+_7189856 1.95 ENSDART00000092114
si:ch73-383l1.1
si:ch73-383l1.1
chr9_-_33749556 1.95 ENSDART00000149383
ndp
Norrie disease (pseudoglioma)
chr5_-_50640171 1.89 ENSDART00000183353
mctp1a
multiple C2 domains, transmembrane 1a
chr16_-_17162485 1.88 ENSDART00000123011
iffo1b
intermediate filament family orphan 1b
chr7_-_15413019 1.87 ENSDART00000172147
si:ch211-106j24.1
si:ch211-106j24.1
chr3_-_24205339 1.87 ENSDART00000157135
si:dkey-110g7.8
si:dkey-110g7.8
chr23_-_36823932 1.86 ENSDART00000142305
hipk1a
homeodomain interacting protein kinase 1a
chr19_-_10881486 1.85 ENSDART00000168852
ENSDART00000160438
PSMD4 (1 of many)
psmd4a
proteasome 26S subunit, non-ATPase 4
proteasome 26S subunit, non-ATPase 4a
chr11_-_9948487 1.85 ENSDART00000189677
ENSDART00000113171
nlgn1
neuroligin 1
chr22_+_28446365 1.85 ENSDART00000189359
abi3bpb
ABI family, member 3 (NESH) binding protein b
chr23_+_29966466 1.85 ENSDART00000143583
dvl1a
dishevelled segment polarity protein 1a
chr19_-_10881141 1.81 ENSDART00000162793
psmd4a
proteasome 26S subunit, non-ATPase 4a
chr8_-_13177536 1.81 ENSDART00000100992
zgc:194990
zgc:194990
chr23_+_28128453 1.81 ENSDART00000182618
c1galt1a
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a
chr7_+_24114694 1.80 ENSDART00000127177
mrpl52
mitochondrial ribosomal protein L52
chr5_+_19314574 1.76 ENSDART00000133247
rusc2
RUN and SH3 domain containing 2
chr18_-_46763170 1.75 ENSDART00000171880
dner
delta/notch-like EGF repeat containing
chr1_-_214911 1.75 ENSDART00000060971
dcun1d2b
DCN1, defective in cullin neddylation 1, domain containing 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of mafk

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.3 GO:0021557 oculomotor nerve development(GO:0021557)
2.3 6.9 GO:0015824 proline transport(GO:0015824)
1.7 5.0 GO:0010265 SCF complex assembly(GO:0010265)
1.4 7.0 GO:0035988 chondrocyte proliferation(GO:0035988)
1.3 3.9 GO:1901004 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
1.0 6.0 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.7 8.1 GO:0061718 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.7 6.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.7 32.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.7 10.1 GO:0043248 proteasome assembly(GO:0043248)
0.7 6.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.6 5.7 GO:1904861 excitatory synapse assembly(GO:1904861)
0.6 1.8 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.6 1.8 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.6 2.3 GO:1902260 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.6 10.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.5 7.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.5 7.1 GO:0044247 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.5 4.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.5 4.8 GO:0051601 exocyst localization(GO:0051601)
0.5 13.2 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.5 8.8 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.5 1.8 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.4 1.3 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341) intermediate mesoderm development(GO:0048389)
0.4 3.9 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.4 2.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.4 2.3 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.4 8.9 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4 2.5 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.3 1.0 GO:0042706 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.3 2.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.3 7.4 GO:0031033 myosin filament organization(GO:0031033)
0.3 6.0 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.3 1.7 GO:0033034 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.3 1.9 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.3 2.7 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.3 1.4 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.3 3.0 GO:0034394 protein localization to cell surface(GO:0034394)
0.3 4.0 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.3 1.8 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.3 2.9 GO:0036368 cone photoresponse recovery(GO:0036368)
0.3 5.9 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.3 6.7 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.2 2.9 GO:0033198 response to ATP(GO:0033198)
0.2 11.4 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 1.2 GO:0032877 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.2 4.9 GO:0006825 copper ion transport(GO:0006825)
0.2 7.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.2 2.9 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.2 1.7 GO:0043090 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.2 7.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2 1.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 0.9 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.2 12.1 GO:0006414 translational elongation(GO:0006414)
0.2 10.7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.2 0.2 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.2 1.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 1.7 GO:0061709 reticulophagy(GO:0061709)
0.2 9.8 GO:0045214 sarcomere organization(GO:0045214)
0.2 2.7 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.2 1.9 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.2 2.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.2 2.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 9.0 GO:1901214 regulation of neuron death(GO:1901214)
0.2 2.0 GO:0061337 cardiac conduction(GO:0061337)
0.1 0.7 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.4 GO:0070197 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.7 GO:0036503 ERAD pathway(GO:0036503)
0.1 0.6 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.1 2.1 GO:0060325 face morphogenesis(GO:0060325)
0.1 4.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.7 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.1 1.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 4.1 GO:0050708 regulation of protein secretion(GO:0050708)
0.1 1.8 GO:0045116 protein neddylation(GO:0045116) positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 1.3 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 8.9 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 4.9 GO:0006289 nucleotide-excision repair(GO:0006289)
0.1 0.3 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 1.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.7 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 1.9 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 5.5 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1 1.0 GO:0034333 adherens junction assembly(GO:0034333)
0.1 2.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.5 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 1.4 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 2.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.8 GO:0001765 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 4.7 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 1.0 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 3.3 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 1.5 GO:0014823 response to activity(GO:0014823)
0.1 2.8 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 2.4 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.1 4.8 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 0.7 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 2.0 GO:0006829 zinc II ion transport(GO:0006829)
0.1 0.3 GO:0071962 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.1 1.9 GO:0043171 peptide catabolic process(GO:0043171)
0.1 11.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.1 0.9 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 0.2 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.1 1.8 GO:0032543 mitochondrial translation(GO:0032543)
0.1 1.4 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.1 17.2 GO:0030334 regulation of cell migration(GO:0030334)
0.1 1.2 GO:0035329 hippo signaling(GO:0035329)
0.1 1.2 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.1 0.2 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 1.3 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 2.9 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 1.2 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 1.1 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 1.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 15.6 GO:0099536 synaptic signaling(GO:0099536)
0.0 2.1 GO:0007254 JNK cascade(GO:0007254)
0.0 2.8 GO:0006612 protein targeting to membrane(GO:0006612)
0.0 0.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 2.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.0 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 2.1 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.4 GO:1902656 calcium ion transmembrane import into cytosol(GO:0097553) inorganic cation import into cell(GO:0098659) calcium ion import across plasma membrane(GO:0098703) inorganic ion import into cell(GO:0099587) calcium ion import into cytosol(GO:1902656) calcium ion import into cell(GO:1990035)
0.0 2.0 GO:0050770 regulation of axonogenesis(GO:0050770)
0.0 0.1 GO:0021794 thalamus development(GO:0021794)
0.0 2.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.6 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 2.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 5.9 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828)
0.0 3.7 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 8.2 GO:0060322 head development(GO:0060322)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 8.0 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 1.2 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.4 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.0 2.0 GO:0033674 positive regulation of kinase activity(GO:0033674)
0.0 1.1 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 1.7 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 5.8 GO:0051603 proteolysis involved in cellular protein catabolic process(GO:0051603)
0.0 3.2 GO:0032259 methylation(GO:0032259)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.3 GO:0030314 junctional membrane complex(GO:0030314)
1.2 7.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.9 9.1 GO:0042583 chromaffin granule(GO:0042583)
0.8 2.5 GO:0034515 proteasome storage granule(GO:0034515)
0.7 8.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.7 8.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.6 8.4 GO:1990246 uniplex complex(GO:1990246)
0.6 6.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.6 8.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.5 2.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.4 6.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 22.4 GO:0030426 growth cone(GO:0030426)
0.4 3.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.4 6.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 13.5 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.3 1.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.3 18.7 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.3 3.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.3 2.5 GO:0061700 GATOR2 complex(GO:0061700)
0.3 3.1 GO:0008180 COP9 signalosome(GO:0008180)
0.3 8.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 2.6 GO:0070449 elongin complex(GO:0070449)
0.3 11.9 GO:0031941 filamentous actin(GO:0031941)
0.2 5.7 GO:0031594 neuromuscular junction(GO:0031594)
0.2 3.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 3.9 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 2.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 1.5 GO:0042788 polysomal ribosome(GO:0042788)
0.2 4.8 GO:0000145 exocyst(GO:0000145)
0.2 19.2 GO:0005882 intermediate filament(GO:0005882)
0.2 4.1 GO:0034399 nuclear periphery(GO:0034399)
0.2 2.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 4.4 GO:0035371 microtubule plus-end(GO:0035371)
0.1 2.8 GO:0043195 terminal bouton(GO:0043195)
0.1 15.3 GO:0043025 neuronal cell body(GO:0043025)
0.1 10.9 GO:0030018 Z disc(GO:0030018)
0.1 1.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.8 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 2.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 9.8 GO:0031201 SNARE complex(GO:0031201)
0.1 2.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 1.0 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 1.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 2.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.5 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.9 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 2.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.2 GO:0030667 secretory granule membrane(GO:0030667)
0.1 2.4 GO:0035869 ciliary transition zone(GO:0035869)
0.1 8.4 GO:0008021 synaptic vesicle(GO:0008021)
0.1 0.9 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 2.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.7 GO:0036452 ESCRT complex(GO:0036452)
0.0 2.9 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.2 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 18.8 GO:0045202 synapse(GO:0045202)
0.0 3.8 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.1 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 2.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 1.7 GO:0005741 mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.0 5.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 0.8 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 4.0 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 14.9 GO:0044548 S100 protein binding(GO:0044548)
2.7 13.5 GO:0016531 copper chaperone activity(GO:0016531)
1.8 7.1 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.8 4.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.8 7.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.8 6.3 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.7 8.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.7 3.3 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.7 4.0 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.5 3.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.5 5.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.5 7.2 GO:0070628 proteasome binding(GO:0070628)
0.5 1.5 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.5 1.8 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.4 6.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.4 7.3 GO:0045159 myosin II binding(GO:0045159)
0.4 6.0 GO:2001069 glycogen binding(GO:2001069)
0.4 2.3 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.4 2.5 GO:0070728 leucine binding(GO:0070728)
0.3 1.7 GO:0015288 porin activity(GO:0015288)
0.3 2.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 1.4 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.3 7.1 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.3 8.3 GO:0051787 misfolded protein binding(GO:0051787)
0.3 6.0 GO:0003785 actin monomer binding(GO:0003785)
0.3 1.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.3 12.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 11.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3 1.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.3 1.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 9.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 2.9 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.7 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.2 3.6 GO:0001671 ATPase activator activity(GO:0001671)
0.2 1.2 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.2 2.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 0.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 7.6 GO:0051087 chaperone binding(GO:0051087)
0.2 6.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 11.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 7.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 1.6 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 6.8 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.2 2.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 4.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 0.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 2.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 12.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 4.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 3.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 3.0 GO:0005112 Notch binding(GO:0005112)
0.1 1.3 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 2.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 1.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 11.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 1.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 3.9 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.1 2.8 GO:0019905 syntaxin binding(GO:0019905)
0.1 3.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 7.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 1.5 GO:0005344 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.1 10.4 GO:0005179 hormone activity(GO:0005179)
0.1 7.3 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 25.4 GO:0015631 tubulin binding(GO:0015631)
0.1 4.8 GO:0000149 SNARE binding(GO:0000149)
0.1 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 1.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 6.9 GO:0015293 symporter activity(GO:0015293)
0.0 1.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 23.1 GO:0003779 actin binding(GO:0003779)
0.0 2.5 GO:0051082 unfolded protein binding(GO:0051082)
0.0 2.0 GO:0046332 SMAD binding(GO:0046332)
0.0 0.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.3 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 2.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.7 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 20.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 4.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.7 GO:0008092 cytoskeletal protein binding(GO:0008092)
0.0 0.5 GO:0017069 snRNA binding(GO:0017069)
0.0 7.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.2 GO:0060090 binding, bridging(GO:0060090)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.2 10.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 2.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 2.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 12.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 3.6 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID ARF 3PATHWAY Arf1 pathway
0.0 1.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 2.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.3 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.2 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 14.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.9 7.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.6 2.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 2.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.3 2.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 1.8 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 9.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.2 0.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 9.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 4.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 0.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 0.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 0.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases