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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for maza+mazb

Z-value: 4.15

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Transcription factors associated with maza+mazb

Gene Symbol Gene ID Gene Info
mazb
ENSDARG00000063555 si_ch211-166g5.4
maza
ENSDARG00000087330 MYC-associated zinc finger protein a (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mazadr11_v1_chr3_-_21106093_211060930.631.2e-11Click!
si:ch211-166g5.4dr11_v1_chr12_-_3778848_37788480.551.0e-08Click!

Activity profile of maza+mazb motif

Sorted Z-values of maza+mazb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_30642819 97.86 ENSDART00000078154
npas4a
neuronal PAS domain protein 4a
chr16_-_17207754 69.80 ENSDART00000063804
wu:fj39g12
wu:fj39g12
chr3_+_32425202 69.34 ENSDART00000156464
prr12b
proline rich 12b
chr24_-_4973765 69.12 ENSDART00000127597
zic1
zic family member 1 (odd-paired homolog, Drosophila)
chr1_-_39943596 69.07 ENSDART00000149730
stox2a
storkhead box 2a
chr21_+_26697536 65.75 ENSDART00000004109
gng3
guanine nucleotide binding protein (G protein), gamma 3
chr19_-_5254699 62.27 ENSDART00000081951
stx1b
syntaxin 1B
chr25_+_37366698 62.02 ENSDART00000165400
ENSDART00000192589
slc1a2b
solute carrier family 1 (glial high affinity glutamate transporter), member 2b
chr2_-_9646857 56.36 ENSDART00000056901
zgc:153615
zgc:153615
chr14_+_22172047 55.83 ENSDART00000114750
ENSDART00000148259
gabrb2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr7_-_58098814 55.27 ENSDART00000147287
ENSDART00000043984
ank2b
ankyrin 2b, neuronal
chr11_-_1291012 54.88 ENSDART00000158390
atp2b2
ATPase plasma membrane Ca2+ transporting 2
chr14_+_34486629 52.10 ENSDART00000131861
tmsb2
thymosin beta 2
chr2_-_44183613 51.64 ENSDART00000079596
cadm3
cell adhesion molecule 3
chr24_+_41931585 51.27 ENSDART00000130310
epb41l3a
erythrocyte membrane protein band 4.1-like 3a
chr21_+_5169154 50.10 ENSDART00000102559
zgc:122979
zgc:122979
chr1_-_31505144 48.77 ENSDART00000087115
rims1b
regulating synaptic membrane exocytosis 1b
chr1_-_45647846 48.55 ENSDART00000186881
BX511120.1

chr16_-_27640995 47.94 ENSDART00000019658
nacad
NAC alpha domain containing
chr17_+_26569601 47.65 ENSDART00000153897
ndnfl
neuron-derived neurotrophic factor , like
chr6_-_20875111 45.68 ENSDART00000115118
ENSDART00000159916
tns1a
tensin 1a
chr5_-_67878064 45.29 ENSDART00000111203
tagln3a
transgelin 3a
chr6_+_38381957 45.22 ENSDART00000087300
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr2_-_38125657 45.15 ENSDART00000143433
cbln12
cerebellin 12
chr3_-_30861177 44.83 ENSDART00000154811
shank1
SH3 and multiple ankyrin repeat domains 1
chr4_+_2619132 44.50 ENSDART00000128807
gpr22a
G protein-coupled receptor 22a
chr11_-_97817 44.47 ENSDART00000092903
elmo2
engulfment and cell motility 2
chr8_+_22931427 44.12 ENSDART00000063096
sypa
synaptophysin a
chr3_+_54168007 43.66 ENSDART00000109894
olfm2a
olfactomedin 2a
chr1_-_38709551 43.66 ENSDART00000128794
gpm6ab
glycoprotein M6Ab
chr2_+_22694382 43.34 ENSDART00000139196
kif1ab
kinesin family member 1Ab
chr21_-_21373242 43.14 ENSDART00000079629
ppm1nb
protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative)
chr10_-_37337579 42.89 ENSDART00000147705
omga
oligodendrocyte myelin glycoprotein a
chr18_-_44610992 42.84 ENSDART00000125968
ENSDART00000185836
spred3
sprouty-related, EVH1 domain containing 3
chr11_+_36989696 42.44 ENSDART00000045888
tkta
transketolase a
chr14_+_44545092 42.44 ENSDART00000175454
lingo2a
leucine rich repeat and Ig domain containing 2a
chr10_-_35542071 41.95 ENSDART00000162139
si:ch211-244c8.4
si:ch211-244c8.4
chr3_-_22212764 41.88 ENSDART00000155490
maptb
microtubule-associated protein tau b
chr6_+_22597362 41.43 ENSDART00000131242
cygb2
cytoglobin 2
chr17_-_46457622 40.46 ENSDART00000130215
TMEM179 (1 of many)
transmembrane protein 179
chr3_-_30625219 40.13 ENSDART00000151698
syt3
synaptotagmin III
chr3_+_37827373 39.52 ENSDART00000039517
asic2
acid-sensing (proton-gated) ion channel 2
chr16_-_36798783 39.39 ENSDART00000145697
calb1
calbindin 1
chr2_-_44183451 38.90 ENSDART00000111246
cadm3
cell adhesion molecule 3
chr25_+_19954576 38.38 ENSDART00000149335
kcna1a
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr12_+_15363463 38.34 ENSDART00000133533
plxdc1
plexin domain containing 1
chr11_-_44030962 37.88 ENSDART00000171910
FP016005.1

chr13_+_11436130 36.98 ENSDART00000169895
zbtb18
zinc finger and BTB domain containing 18
chr11_-_44543082 36.93 ENSDART00000099568
gpr137bb
G protein-coupled receptor 137Bb
chr8_+_32516160 36.88 ENSDART00000061786
ncs1b
neuronal calcium sensor 1b
chr16_-_9383629 36.47 ENSDART00000084264
ENSDART00000166958
adcy2a
adenylate cyclase 2a
chr1_-_29045426 36.40 ENSDART00000019770
gpm6ba
glycoprotein M6Ba
chr3_+_37824268 36.14 ENSDART00000137038
asic2
acid-sensing (proton-gated) ion channel 2
chr12_-_10705916 35.97 ENSDART00000164038
FO704786.1

chr8_-_14052349 34.29 ENSDART00000135811
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr25_-_19395476 33.88 ENSDART00000182622
map1ab
microtubule-associated protein 1Ab
chr14_-_25577094 33.68 ENSDART00000163669
cplx2
complexin 2
chr13_+_38430466 33.67 ENSDART00000132691
adgrb3
adhesion G protein-coupled receptor B3
chr21_-_43015383 33.56 ENSDART00000065097
dpysl3
dihydropyrimidinase-like 3
chr7_+_528593 33.42 ENSDART00000091955
nrxn2b
neurexin 2b
chr12_-_13886952 33.29 ENSDART00000110503
adam11
ADAM metallopeptidase domain 11
chr13_+_11440389 33.15 ENSDART00000186463
zbtb18
zinc finger and BTB domain containing 18
chr19_+_9533008 32.86 ENSDART00000104607
fam131ba
family with sequence similarity 131, member Ba
chr11_-_32723851 32.67 ENSDART00000155592
pcdh17
protocadherin 17
chr16_-_44349845 32.44 ENSDART00000170932
rims2a
regulating synaptic membrane exocytosis 2a
chr8_+_46418996 32.26 ENSDART00000144285
si:ch211-196g2.4
si:ch211-196g2.4
chr17_-_26926577 32.22 ENSDART00000050202
rcan3
regulator of calcineurin 3
chr7_+_27977065 31.98 ENSDART00000089574
tub
tubby bipartite transcription factor
chr20_+_20672163 31.61 ENSDART00000027758
rtn1b
reticulon 1b
chr23_+_6232895 31.56 ENSDART00000139795
syt2a
synaptotagmin IIa
chr1_-_22861348 31.33 ENSDART00000139412
SMIM18
si:dkey-92j12.6
chr13_-_31435137 31.30 ENSDART00000057441
rtn1a
reticulon 1a
chr6_+_54888493 31.11 ENSDART00000113331
nav1b
neuron navigator 1b
chr25_-_11088839 31.02 ENSDART00000154748
sv2bb
synaptic vesicle glycoprotein 2Bb
chr10_-_7974155 30.56 ENSDART00000147368
ENSDART00000075524
osbp2
oxysterol binding protein 2
chr3_-_38692920 30.54 ENSDART00000155042
mpp3a
membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3)
chr13_+_1100197 30.24 ENSDART00000139560
ppp3r1a
protein phosphatase 3, regulatory subunit B, alpha a
chr16_-_16590780 30.08 ENSDART00000059841
si:ch211-257p13.3
si:ch211-257p13.3
chr10_+_1849874 29.93 ENSDART00000158897
ENSDART00000149956
apc
adenomatous polyposis coli
chr3_-_21037840 29.65 ENSDART00000002393
rundc3aa
RUN domain containing 3Aa
chr8_+_28527776 29.63 ENSDART00000053782
scrt2
scratch family zinc finger 2
chr3_-_28075756 29.22 ENSDART00000122037
rbfox1
RNA binding fox-1 homolog 1
chr17_-_44247707 29.01 ENSDART00000126097
otx2b
orthodenticle homeobox 2b
chr19_+_30633453 28.87 ENSDART00000052124
fam49al
family with sequence similarity 49, member A-like
chr3_-_19133003 28.59 ENSDART00000145215
grin2ca
glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca
chr14_+_30730749 28.31 ENSDART00000087884
ccdc85b
coiled-coil domain containing 85B
chr13_-_21739142 27.76 ENSDART00000078460
si:dkey-191g9.5
si:dkey-191g9.5
chr7_+_19882066 27.74 ENSDART00000111144
TMEM151A
transmembrane protein 151A
chr6_-_11780070 27.47 ENSDART00000151195
march7
membrane-associated ring finger (C3HC4) 7
chr4_+_19534833 27.42 ENSDART00000140028
lrrc4.1
leucine rich repeat containing 4.1
chr14_-_39074539 27.28 ENSDART00000030509
glra4a
glycine receptor, alpha 4a
chr11_-_23322182 27.24 ENSDART00000111289
kiss1
KiSS-1 metastasis-suppressor
chr2_-_32555625 27.13 ENSDART00000056641
ENSDART00000137531
smarcd3a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr21_-_15200556 26.63 ENSDART00000141809
sfswap
splicing factor SWAP
chr6_+_6850821 26.52 ENSDART00000166607
ENSDART00000111024
zgc:171558
zgc:171558
chr3_-_36115339 26.34 ENSDART00000187406
ENSDART00000123505
ENSDART00000151775
rab11fip4a
RAB11 family interacting protein 4 (class II) a
chr7_-_69521481 26.33 ENSDART00000148465
slc1a1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr5_+_9348284 25.70 ENSDART00000149417
tal2
T-cell acute lymphocytic leukemia 2
chr16_-_31435020 25.46 ENSDART00000138508
zgc:194210
zgc:194210
chr8_+_48603398 24.86 ENSDART00000074900
zgc:195023
zgc:195023
chr5_+_38263240 24.75 ENSDART00000051231
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr3_-_28250722 24.51 ENSDART00000165936
rbfox1
RNA binding fox-1 homolog 1
chr15_-_12500938 24.51 ENSDART00000159627
scn4ba
sodium channel, voltage-gated, type IV, beta a
chr11_+_37137196 24.47 ENSDART00000172950
wnk2
WNK lysine deficient protein kinase 2
chr15_-_33925851 24.42 ENSDART00000187807
ENSDART00000187780
mag
myelin associated glycoprotein
chr10_-_27197044 24.39 ENSDART00000137928
auts2a
autism susceptibility candidate 2a
chr20_-_14665002 24.31 ENSDART00000152816
scrn2
secernin 2
chr8_+_28900689 24.27 ENSDART00000141634
grid2
glutamate receptor, ionotropic, delta 2
chr9_+_13714379 23.53 ENSDART00000017593
ENSDART00000145503
tmem237a
transmembrane protein 237a
chr3_-_21061931 23.47 ENSDART00000036741
fam57ba
family with sequence similarity 57, member Ba
chr17_+_52822422 23.45 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr16_-_44399335 23.43 ENSDART00000165058
rims2a
regulating synaptic membrane exocytosis 2a
chr8_+_13849999 23.41 ENSDART00000143784
doc2d
double C2-like domains, delta
chr6_+_39836474 23.40 ENSDART00000112637
smarcc2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr19_-_25301711 23.32 ENSDART00000175739
rims3
regulating synaptic membrane exocytosis 3
chr6_+_55365632 22.96 ENSDART00000169240
pltp
phospholipid transfer protein
chr7_+_19552381 22.95 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr6_+_58492201 22.84 ENSDART00000156375
kcnq2b
potassium voltage-gated channel, KQT-like subfamily, member 2b
chr25_-_29134654 22.82 ENSDART00000067066
parp6b
poly (ADP-ribose) polymerase family, member 6b
chr3_-_28120092 22.67 ENSDART00000151143
rbfox1
RNA binding fox-1 homolog 1
chr4_-_1360495 22.41 ENSDART00000164623
ptn
pleiotrophin
chr19_+_16032383 22.28 ENSDART00000046530
rab42a
RAB42, member RAS oncogene family a
chr14_-_2369849 21.98 ENSDART00000180422
ENSDART00000189731
ENSDART00000111748
pcdhb
protocadherin b
chr9_+_14152211 21.93 ENSDART00000148055
si:ch211-67e16.11
si:ch211-67e16.11
chr22_+_16418688 21.90 ENSDART00000009360
ankrd29
ankyrin repeat domain 29
chr21_-_26918901 21.82 ENSDART00000100685
lrfn4a
leucine rich repeat and fibronectin type III domain containing 4a
chr18_-_46464501 21.78 ENSDART00000040669
sphkap
SPHK1 interactor, AKAP domain containing
chr17_-_43287290 21.66 ENSDART00000156885
EML5
si:dkey-1f12.3
chr18_-_46763170 21.65 ENSDART00000171880
dner
delta/notch-like EGF repeat containing
chr17_+_15535501 21.52 ENSDART00000002932
marcksb
myristoylated alanine-rich protein kinase C substrate b
chr6_+_54358529 21.50 ENSDART00000153704
anks1ab
ankyrin repeat and sterile alpha motif domain containing 1Ab
chr15_-_5467477 21.47 ENSDART00000123839
arrb1
arrestin, beta 1
chr12_+_35650321 21.46 ENSDART00000190446
BX255898.1

chr18_+_12058403 21.46 ENSDART00000140854
ENSDART00000193632
ENSDART00000190519
ENSDART00000190685
ENSDART00000112671
bicd1a
bicaudal D homolog 1a
chr16_-_8927425 21.16 ENSDART00000000382
triob
trio Rho guanine nucleotide exchange factor b
chr14_-_1990290 21.13 ENSDART00000183382
pcdh2g5
protocadherin 2 gamma 5
chr23_-_31693309 20.93 ENSDART00000146327
sgk1
serum/glucocorticoid regulated kinase 1
chr18_-_39583601 20.81 ENSDART00000125116
tnfaip8l3
tumor necrosis factor, alpha-induced protein 8-like 3
chr25_+_35706493 20.79 ENSDART00000176741
kif21a
kinesin family member 21A
chr9_-_54840124 20.72 ENSDART00000137214
ENSDART00000085693
gpm6bb
glycoprotein M6Bb
chr10_-_26179805 20.66 ENSDART00000174797
trim3b
tripartite motif containing 3b
chr22_+_32120156 20.64 ENSDART00000149666
dock3
dedicator of cytokinesis 3
chr21_-_31143903 20.54 ENSDART00000111571
rap1gap2b
RAP1 GTPase activating protein 2b
chr6_-_35738836 20.43 ENSDART00000111642
brinp3a.1
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr17_+_2063693 20.39 ENSDART00000182349
zgc:162989
zgc:162989
chr13_-_638485 20.05 ENSDART00000066080
ENSDART00000128969
slit1a
slit homolog 1a (Drosophila)
chr21_-_25604603 20.03 ENSDART00000133134
ENSDART00000139460
efemp2b
EGF containing fibulin extracellular matrix protein 2b
chr21_+_1143141 19.93 ENSDART00000178294
CABZ01086139.1

chr14_+_24283915 19.84 ENSDART00000172868
klhl3
kelch-like family member 3
chr10_-_31220558 19.82 ENSDART00000134866
pknox2
pbx/knotted 1 homeobox 2
chr6_-_35779348 19.78 ENSDART00000191159
brinp3a.1
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr24_-_20599781 19.34 ENSDART00000179664
ENSDART00000141823
zbtb47b
zinc finger and BTB domain containing 47b
chr16_-_13109749 19.34 ENSDART00000142610
prkcg
protein kinase C, gamma
chr18_-_44611252 19.34 ENSDART00000173095
spred3
sprouty-related, EVH1 domain containing 3
chr20_+_37661229 19.33 ENSDART00000138539
aig1
androgen-induced 1 (H. sapiens)
chr16_-_25568512 19.21 ENSDART00000149411
atxn1b
ataxin 1b
chr8_+_26868105 19.13 ENSDART00000005337
rimkla
ribosomal modification protein rimK-like family member A
chr22_+_18951096 19.03 ENSDART00000187010
hcn2b
hyperpolarization activated cyclic nucleotide-gated potassium channel 2b
chr2_+_28889936 18.99 ENSDART00000078232
cdh10a
cadherin 10, type 2a (T2-cadherin)
chr13_-_32995324 18.89 ENSDART00000140542
ENSDART00000037740
kcnf1b
potassium voltage-gated channel, subfamily F, member 1b
chr12_+_32729470 18.85 ENSDART00000175712
rbfox3a
RNA binding fox-1 homolog 3a
chr12_+_16233077 18.75 ENSDART00000152409
mpp3b
membrane protein, palmitoylated 3b (MAGUK p55 subfamily member 3)
chr13_+_28854438 18.70 ENSDART00000193407
ENSDART00000189554
CU639469.1

chr7_+_36041509 18.20 ENSDART00000162850
irx3a
iroquois homeobox 3a
chr10_+_10210455 18.13 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr15_-_12113045 18.08 ENSDART00000159879
dscaml1
Down syndrome cell adhesion molecule like 1
chr24_-_6501211 18.04 ENSDART00000186241
ENSDART00000109040
ENSDART00000136154
gpr158a
G protein-coupled receptor 158a
chr12_+_24561832 17.96 ENSDART00000088159
nrxn1a
neurexin 1a
chr4_+_20255160 17.70 ENSDART00000188658
lrtm2a
leucine-rich repeats and transmembrane domains 2a
chr13_+_27073901 17.64 ENSDART00000146227
slc24a3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr19_-_32804535 17.59 ENSDART00000175613
ENSDART00000052098
nt5c1aa
5'-nucleotidase, cytosolic IAa
chr15_-_2188332 16.98 ENSDART00000138941
ENSDART00000009564
shox2
short stature homeobox 2
chr7_-_41468942 16.93 ENSDART00000174087
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr14_+_34547554 16.90 ENSDART00000074819
gabrp
gamma-aminobutyric acid (GABA) A receptor, pi
chr2_-_36818132 16.75 ENSDART00000110447
slitrk3b
SLIT and NTRK-like family, member 3b
chr16_-_12914288 16.60 ENSDART00000184221
cacng8b
calcium channel, voltage-dependent, gamma subunit 8b
chr11_-_3334248 16.59 ENSDART00000154314
ENSDART00000121861
prph
peripherin
chr11_-_23080970 16.55 ENSDART00000127791
atp2b2
ATPase plasma membrane Ca2+ transporting 2
chr15_-_20024205 16.44 ENSDART00000161379
auts2b
autism susceptibility candidate 2b
chr17_+_25955003 16.40 ENSDART00000156029
grid1a
glutamate receptor, ionotropic, delta 1a
chr9_+_17787864 16.39 ENSDART00000013111
dgkh
diacylglycerol kinase, eta
chr9_-_27442339 16.33 ENSDART00000138602
stxbp5l
syntaxin binding protein 5-like
chr13_+_11439486 16.09 ENSDART00000138312
zbtb18
zinc finger and BTB domain containing 18
chr1_+_37391141 16.00 ENSDART00000083593
ENSDART00000168647
sparcl1
SPARC-like 1
chr21_-_37889727 16.00 ENSDART00000163612
ENSDART00000180958
gabrb4
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr25_+_22730490 15.98 ENSDART00000149455
abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr10_-_26729930 15.77 ENSDART00000145532
fgf13b
fibroblast growth factor 13b
chr13_-_33007781 15.73 ENSDART00000183671
ENSDART00000179859
rbm25a
RNA binding motif protein 25a
chr16_+_13855039 15.72 ENSDART00000113764
ENSDART00000143983
zgc:174888
zgc:174888
chr8_+_25254435 15.66 ENSDART00000143554
ampd2b
adenosine monophosphate deaminase 2b
chr16_+_17389116 15.55 ENSDART00000103750
ENSDART00000173448
fam131bb
family with sequence similarity 131, member Bb
chr4_+_20812900 15.47 ENSDART00000005847
nav3
neuron navigator 3
chr7_-_49651378 15.27 ENSDART00000015040
hrasb
-Ha-ras Harvey rat sarcoma viral oncogene homolog b
chr8_-_7391721 14.99 ENSDART00000149836
lhfpl4b
LHFPL tetraspan subfamily member 4b
chr15_+_7992906 14.97 ENSDART00000090790
cadm2b
cell adhesion molecule 2b
chr8_-_40251126 14.89 ENSDART00000180435
kdm2ba
lysine (K)-specific demethylase 2Ba
chr19_-_1961024 14.89 ENSDART00000108784
mturn
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr14_+_11762991 14.81 ENSDART00000110004
frmpd3
FERM and PDZ domain containing 3
chr2_+_3595333 14.80 ENSDART00000041052
c1ql3b
complement component 1, q subcomponent-like 3b
chr11_-_23025949 14.80 ENSDART00000184859
ENSDART00000167818
ENSDART00000046122
ENSDART00000193120
atp2b2
ATPase plasma membrane Ca2+ transporting 2

Network of associatons between targets according to the STRING database.

First level regulatory network of maza+mazb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
19.6 97.9 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
19.0 57.1 GO:1903792 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
12.5 62.3 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
12.3 36.9 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
11.2 67.0 GO:0035332 positive regulation of hippo signaling(GO:0035332)
11.1 55.3 GO:0036371 protein localization to T-tubule(GO:0036371)
10.7 64.0 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
9.9 69.1 GO:0021534 cell proliferation in hindbrain(GO:0021534)
9.8 39.4 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
8.5 42.4 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
7.9 173.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
7.7 23.0 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
7.5 29.9 GO:1905067 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
7.2 21.6 GO:0014014 negative regulation of gliogenesis(GO:0014014)
6.7 33.7 GO:0016322 neuron remodeling(GO:0016322)
6.6 19.8 GO:0072156 distal tubule morphogenesis(GO:0072156)
6.4 51.3 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
6.3 38.1 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
5.7 51.3 GO:1904861 excitatory synapse assembly(GO:1904861)
5.6 50.5 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
5.4 21.5 GO:0001774 microglial cell activation(GO:0001774) regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
5.2 52.1 GO:0042989 sequestering of actin monomers(GO:0042989)
5.0 15.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
4.8 19.3 GO:0060074 synapse maturation(GO:0060074)
4.5 13.6 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
4.4 26.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
4.0 40.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
3.9 11.8 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
3.7 11.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
3.7 29.6 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516)
3.6 21.5 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
3.5 38.3 GO:0099565 excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
3.5 13.9 GO:0038093 Fc receptor signaling pathway(GO:0038093)
3.5 6.9 GO:0001919 regulation of receptor recycling(GO:0001919)
3.5 13.8 GO:0010226 response to lithium ion(GO:0010226)
3.4 77.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
3.2 22.4 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
3.0 14.9 GO:0030219 megakaryocyte differentiation(GO:0030219)
2.8 69.8 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
2.7 21.5 GO:0050714 positive regulation of protein secretion(GO:0050714)
2.6 13.1 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
2.5 27.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
2.4 61.4 GO:0008345 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
2.2 13.4 GO:0050936 xanthophore differentiation(GO:0050936)
2.2 6.6 GO:1904969 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
2.1 62.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
2.0 28.7 GO:0032264 IMP salvage(GO:0032264)
2.0 8.2 GO:0042481 regulation of odontogenesis(GO:0042481)
2.0 41.4 GO:0015671 oxygen transport(GO:0015671)
1.9 5.8 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
1.9 9.6 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
1.9 44.6 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
1.8 8.9 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
1.8 31.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
1.8 7.1 GO:1903589 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
1.7 5.2 GO:0035992 tendon formation(GO:0035992)
1.7 29.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
1.6 141.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
1.6 44.5 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
1.6 39.4 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
1.5 24.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
1.5 4.5 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
1.5 6.0 GO:0090161 Golgi ribbon formation(GO:0090161)
1.5 6.0 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
1.4 41.4 GO:0070593 dendrite self-avoidance(GO:0070593)
1.4 8.5 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
1.4 14.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
1.4 22.2 GO:1902307 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
1.4 6.8 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
1.4 17.6 GO:0046085 adenosine metabolic process(GO:0046085)
1.3 6.6 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
1.3 9.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
1.3 3.9 GO:0055016 hypochord development(GO:0055016)
1.3 5.1 GO:0070987 error-free translesion synthesis(GO:0070987)
1.3 5.1 GO:0034969 histone arginine methylation(GO:0034969)
1.3 20.0 GO:0045773 positive regulation of axon extension(GO:0045773)
1.2 6.2 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
1.2 15.5 GO:0072576 liver morphogenesis(GO:0072576)
1.2 7.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
1.2 27.2 GO:0033555 neuronal action potential(GO:0019228) multicellular organismal response to stress(GO:0033555)
1.2 7.0 GO:0003232 bulbus arteriosus development(GO:0003232)
1.1 15.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
1.1 8.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
1.1 16.6 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
1.1 5.5 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
1.1 10.8 GO:0097499 protein localization to nonmotile primary cilium(GO:0097499)
1.1 18.1 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
1.1 13.8 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
1.1 40.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
1.0 26.8 GO:0070050 neuron cellular homeostasis(GO:0070050)
1.0 44.1 GO:0006171 cAMP biosynthetic process(GO:0006171)
1.0 7.0 GO:0034389 lipid particle organization(GO:0034389)
1.0 69.8 GO:1902476 chloride transmembrane transport(GO:1902476)
1.0 4.9 GO:0021754 facial nucleus development(GO:0021754)
1.0 20.0 GO:0048251 elastic fiber assembly(GO:0048251)
1.0 33.4 GO:0061512 protein localization to cilium(GO:0061512)
1.0 14.3 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.9 17.5 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.9 32.7 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.9 5.3 GO:0007603 phototransduction, visible light(GO:0007603)
0.9 20.5 GO:0043486 histone exchange(GO:0043486)
0.8 10.9 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.8 9.1 GO:0021654 rhombomere boundary formation(GO:0021654)
0.8 23.2 GO:0050708 regulation of protein secretion(GO:0050708)
0.8 3.2 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.8 7.2 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.8 25.7 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.8 9.1 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.7 6.7 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.7 161.2 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.7 10.3 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.7 31.7 GO:0031102 neuron projection regeneration(GO:0031102)
0.7 27.2 GO:0051588 regulation of neurotransmitter secretion(GO:0046928) regulation of neurotransmitter transport(GO:0051588)
0.7 16.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.7 9.0 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.7 10.4 GO:0042407 cristae formation(GO:0042407)
0.7 4.1 GO:0048713 positive regulation of glial cell differentiation(GO:0045687) regulation of oligodendrocyte differentiation(GO:0048713) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.7 21.8 GO:0032482 Rab protein signal transduction(GO:0032482)
0.7 67.3 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.7 4.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.7 8.5 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.7 6.5 GO:0036368 cone photoresponse recovery(GO:0036368)
0.6 2.5 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.6 7.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.6 22.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.6 14.9 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.6 8.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.6 31.1 GO:0001764 neuron migration(GO:0001764)
0.6 11.0 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.6 6.4 GO:0021703 locus ceruleus development(GO:0021703)
0.6 14.3 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.6 14.0 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.6 22.4 GO:0051781 positive regulation of cell division(GO:0051781)
0.6 2.2 GO:0045685 regulation of glial cell differentiation(GO:0045685)
0.5 35.7 GO:0006836 neurotransmitter transport(GO:0006836)
0.5 3.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.5 3.1 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.5 94.9 GO:0006813 potassium ion transport(GO:0006813)
0.5 43.5 GO:0006612 protein targeting to membrane(GO:0006612)
0.5 26.3 GO:0032465 regulation of cytokinesis(GO:0032465)
0.5 29.1 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.5 29.7 GO:0050919 negative chemotaxis(GO:0050919)
0.5 20.5 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.5 42.9 GO:0019722 calcium-mediated signaling(GO:0019722)
0.5 8.5 GO:0010458 microtubule nucleation(GO:0007020) exit from mitosis(GO:0010458)
0.5 14.6 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.5 2.8 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.5 9.2 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.5 13.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.4 101.4 GO:0007018 microtubule-based movement(GO:0007018)
0.4 7.6 GO:0046058 cAMP metabolic process(GO:0046058)
0.4 11.3 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.4 12.9 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.4 44.0 GO:0090630 activation of GTPase activity(GO:0090630)
0.3 8.8 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.3 11.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.3 14.2 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.3 33.5 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.3 5.6 GO:0002574 thrombocyte differentiation(GO:0002574) macrophage differentiation(GO:0030225)
0.3 9.0 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.3 8.9 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.3 47.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3 1.1 GO:0070293 renal absorption(GO:0070293)
0.3 11.7 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.3 4.2 GO:0016926 protein desumoylation(GO:0016926)
0.2 8.4 GO:0045332 phospholipid translocation(GO:0045332)
0.2 5.2 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.2 3.6 GO:0009798 axis specification(GO:0009798)
0.2 4.9 GO:0009649 entrainment of circadian clock(GO:0009649)
0.2 1.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 7.1 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.2 27.8 GO:0006909 phagocytosis(GO:0006909)
0.2 7.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 15.4 GO:0030042 actin filament depolymerization(GO:0030042)
0.2 3.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.2 3.0 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.2 7.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 0.5 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378) vitamin D biosynthetic process(GO:0042368) cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.2 0.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 8.7 GO:0008360 regulation of cell shape(GO:0008360)
0.2 7.1 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.2 1.7 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1 1.9 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 19.8 GO:0048511 rhythmic process(GO:0048511)
0.1 2.8 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 3.9 GO:0045664 regulation of neuron differentiation(GO:0045664)
0.1 4.8 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 1.3 GO:0006188 IMP biosynthetic process(GO:0006188)
0.1 2.4 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.1 5.5 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 13.9 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.1 24.9 GO:0006869 lipid transport(GO:0006869)
0.1 5.0 GO:0008016 regulation of heart contraction(GO:0008016)
0.1 4.7 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 2.1 GO:0019229 regulation of vasoconstriction(GO:0019229)
0.1 6.7 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.1 4.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 33.9 GO:0031175 neuron projection development(GO:0031175)
0.1 47.3 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.1 14.8 GO:0060271 cilium morphogenesis(GO:0060271)
0.1 0.5 GO:0031060 regulation of histone methylation(GO:0031060)
0.1 4.4 GO:0006338 chromatin remodeling(GO:0006338)
0.1 1.7 GO:0001706 endoderm formation(GO:0001706)
0.1 1.8 GO:0001935 endothelial cell proliferation(GO:0001935)
0.1 3.6 GO:0007605 sensory perception of sound(GO:0007605)
0.1 1.7 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 6.3 GO:0007601 visual perception(GO:0007601)
0.0 2.7 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 2.6 GO:0030030 cell projection organization(GO:0030030)
0.0 3.3 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 10.0 GO:0006886 intracellular protein transport(GO:0006886)
0.0 0.5 GO:0070831 basement membrane assembly(GO:0070831)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
8.0 47.9 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
7.7 53.9 GO:0043194 axon initial segment(GO:0043194)
6.3 31.6 GO:0042584 chromaffin granule membrane(GO:0042584)
5.6 33.7 GO:0043083 synaptic cleft(GO:0043083)
4.9 142.2 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
4.4 70.8 GO:0071564 npBAF complex(GO:0071564)
4.3 29.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
3.9 65.8 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
3.6 43.7 GO:0044295 axonal growth cone(GO:0044295)
3.5 13.8 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
3.5 55.3 GO:0030315 T-tubule(GO:0030315)
3.4 44.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
2.9 66.6 GO:0043195 terminal bouton(GO:0043195)
2.8 150.4 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
2.8 67.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
2.3 35.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
2.3 78.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
2.1 20.5 GO:0000812 Swr1 complex(GO:0000812)
1.9 5.8 GO:0070578 RISC-loading complex(GO:0070578)
1.6 44.1 GO:0048786 presynaptic active zone(GO:0048786)
1.6 6.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.4 9.6 GO:0033010 paranodal junction(GO:0033010)
1.2 57.0 GO:0030426 growth cone(GO:0030426)
1.2 14.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
1.1 9.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.9 10.4 GO:0061617 MICOS complex(GO:0061617)
0.9 7.6 GO:0016586 RSC complex(GO:0016586)
0.8 27.3 GO:0034707 chloride channel complex(GO:0034707)
0.8 7.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.8 9.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.8 83.0 GO:0043025 neuronal cell body(GO:0043025)
0.7 14.0 GO:0044666 MLL3/4 complex(GO:0044666)
0.7 60.2 GO:0005871 kinesin complex(GO:0005871)
0.7 5.7 GO:0005614 interstitial matrix(GO:0005614)
0.7 24.0 GO:0032432 actin filament bundle(GO:0032432)
0.7 26.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.7 23.5 GO:0035869 ciliary transition zone(GO:0035869)
0.7 11.2 GO:0015030 Cajal body(GO:0015030)
0.6 11.8 GO:0055037 recycling endosome(GO:0055037)
0.6 33.9 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.6 6.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.5 14.3 GO:0005844 polysome(GO:0005844)
0.5 17.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.5 23.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.4 17.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.4 22.3 GO:0031201 SNARE complex(GO:0031201)
0.4 8.5 GO:0045180 basal cortex(GO:0045180)
0.3 9.6 GO:0042383 sarcolemma(GO:0042383)
0.3 12.8 GO:0030175 filopodium(GO:0030175)
0.3 39.6 GO:0070382 exocytic vesicle(GO:0070382)
0.3 22.3 GO:0000139 Golgi membrane(GO:0000139)
0.3 49.7 GO:0043005 neuron projection(GO:0043005)
0.3 2.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.3 25.8 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.3 36.0 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.3 3.9 GO:0030056 hemidesmosome(GO:0030056)
0.3 33.4 GO:0005929 cilium(GO:0005929)
0.3 70.2 GO:0005874 microtubule(GO:0005874)
0.3 180.0 GO:0030054 cell junction(GO:0030054)
0.2 31.1 GO:0030424 axon(GO:0030424)
0.2 31.1 GO:0045202 synapse(GO:0045202)
0.2 10.8 GO:0005930 axoneme(GO:0005930)
0.2 9.0 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.2 6.5 GO:0072686 mitotic spindle(GO:0072686)
0.2 213.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 4.5 GO:0005811 lipid particle(GO:0005811)
0.1 10.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.8 GO:0030427 site of polarized growth(GO:0030427)
0.1 158.1 GO:0005829 cytosol(GO:0005829)
0.1 11.2 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.1 4.6 GO:0031901 early endosome membrane(GO:0031901)
0.1 70.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 4.3 GO:0005768 endosome(GO:0005768)
0.1 11.0 GO:1990904 ribonucleoprotein complex(GO:1990904)
0.0 21.3 GO:0005739 mitochondrion(GO:0005739)
0.0 1.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)
0.0 204.6 GO:0016021 integral component of membrane(GO:0016021)
0.0 4.3 GO:0016459 myosin complex(GO:0016459)
0.0 48.2 GO:0016020 membrane(GO:0016020)
0.0 0.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.6 GO:0097708 cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.0 131.9 GO:0005634 nucleus(GO:0005634)
0.0 1.7 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
13.1 39.4 GO:0005499 vitamin D binding(GO:0005499)
7.1 42.4 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
6.4 19.1 GO:0072591 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
6.3 75.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
5.9 41.4 GO:0098809 nitrite reductase activity(GO:0098809)
5.7 23.0 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
5.4 32.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
4.9 24.3 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
4.2 120.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
3.8 34.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
3.5 10.4 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
3.2 16.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
3.1 65.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
3.1 49.7 GO:0048495 Roundabout binding(GO:0048495)
3.1 9.2 GO:0042165 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
3.0 27.3 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
2.9 55.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
2.8 14.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
2.8 33.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
2.7 154.2 GO:0044325 ion channel binding(GO:0044325)
2.7 21.5 GO:0034452 dynactin binding(GO:0034452)
2.7 50.5 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
2.6 28.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
2.6 52.1 GO:0003785 actin monomer binding(GO:0003785)
2.6 20.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
2.3 78.1 GO:0004890 GABA-A receptor activity(GO:0004890)
2.3 20.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
2.2 8.9 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
2.2 6.6 GO:0005131 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
2.1 8.3 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
1.9 77.8 GO:0017075 syntaxin-1 binding(GO:0017075)
1.9 38.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
1.8 83.6 GO:0008013 beta-catenin binding(GO:0008013)
1.8 47.3 GO:0004016 adenylate cyclase activity(GO:0004016)
1.7 41.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
1.7 8.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
1.6 62.1 GO:0051087 chaperone binding(GO:0051087)
1.5 4.5 GO:0071253 connexin binding(GO:0071253)
1.5 71.7 GO:0001786 phosphatidylserine binding(GO:0001786)
1.5 7.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.4 5.8 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
1.4 7.1 GO:0060182 apelin receptor activity(GO:0060182)
1.4 7.0 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
1.4 14.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
1.4 11.2 GO:0017070 U6 snRNA binding(GO:0017070)
1.4 20.9 GO:0015459 potassium channel regulator activity(GO:0015459)
1.4 22.2 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
1.3 60.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
1.3 35.0 GO:0015248 sterol transporter activity(GO:0015248)
1.3 14.0 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
1.3 41.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
1.2 12.5 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.2 26.3 GO:0031267 small GTPase binding(GO:0031267)
1.2 17.9 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
1.2 39.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.2 44.6 GO:0030145 manganese ion binding(GO:0030145)
1.2 67.0 GO:0005484 SNAP receptor activity(GO:0005484)
1.1 8.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
1.1 10.8 GO:0042285 xylosyltransferase activity(GO:0042285)
1.1 16.0 GO:0038191 neuropilin binding(GO:0038191)
1.0 20.6 GO:0046875 ephrin receptor binding(GO:0046875)
1.0 6.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
1.0 3.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
1.0 16.3 GO:0045159 myosin II binding(GO:0045159)
0.9 25.6 GO:0005272 sodium channel activity(GO:0005272)
0.9 71.5 GO:0051427 hormone receptor binding(GO:0051427)
0.9 4.6 GO:0070412 R-SMAD binding(GO:0070412)
0.9 11.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.8 17.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.8 4.2 GO:2001070 starch binding(GO:2001070)
0.8 27.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.8 73.3 GO:0008201 heparin binding(GO:0008201)
0.8 14.4 GO:0033691 sialic acid binding(GO:0033691)
0.8 15.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.7 6.7 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.7 61.9 GO:0003777 microtubule motor activity(GO:0003777)
0.7 4.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.7 2.9 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.7 23.5 GO:0051018 protein kinase A binding(GO:0051018)
0.7 3.5 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.7 9.0 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.7 23.5 GO:0005518 collagen binding(GO:0005518)
0.7 16.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.7 10.9 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.7 56.0 GO:0051082 unfolded protein binding(GO:0051082)
0.6 8.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.6 15.2 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.6 10.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.6 9.4 GO:0002039 p53 binding(GO:0002039)
0.6 5.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.6 33.9 GO:0017124 SH3 domain binding(GO:0017124)
0.5 9.7 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.5 2.1 GO:0001596 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.5 6.9 GO:0030552 cAMP binding(GO:0030552)
0.5 2.8 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.4 22.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.4 3.9 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.4 2.9 GO:0070034 telomerase RNA binding(GO:0070034)
0.4 8.5 GO:0050811 GABA receptor binding(GO:0050811)
0.4 16.6 GO:0016247 channel regulator activity(GO:0016247)
0.4 5.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.4 14.9 GO:0032452 histone demethylase activity(GO:0032452)
0.4 99.1 GO:0008017 microtubule binding(GO:0008017)
0.4 71.5 GO:0015293 symporter activity(GO:0015293)
0.4 4.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 122.0 GO:0005096 GTPase activator activity(GO:0005096)
0.3 1.3 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.3 10.9 GO:0019003 GDP binding(GO:0019003)
0.3 26.7 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.3 5.1 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.3 2.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 9.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.3 3.9 GO:0030506 ankyrin binding(GO:0030506)
0.3 4.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.3 14.6 GO:0071949 FAD binding(GO:0071949)
0.2 5.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 11.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.2 8.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.2 6.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 9.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 11.7 GO:0046332 SMAD binding(GO:0046332)
0.2 38.2 GO:0042277 peptide binding(GO:0042277)
0.2 8.4 GO:0004521 endoribonuclease activity(GO:0004521)
0.2 60.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.2 281.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.2 0.5 GO:0031073 vitamin D3 25-hydroxylase activity(GO:0030343) cholesterol 26-hydroxylase activity(GO:0031073)
0.2 27.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.2 1.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 7.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 2.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 16.4 GO:0005516 calmodulin binding(GO:0005516)
0.1 19.5 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 7.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 4.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 19.9 GO:0019901 protein kinase binding(GO:0019901)
0.1 3.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 25.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 3.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 7.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 3.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 8.4 GO:0000287 magnesium ion binding(GO:0000287)
0.1 1.1 GO:0042562 hormone binding(GO:0042562)
0.1 48.0 GO:0005509 calcium ion binding(GO:0005509)
0.1 3.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 5.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 4.3 GO:0003774 motor activity(GO:0003774)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 2.5 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 9.1 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.8 GO:0051287 NAD binding(GO:0051287)
0.0 1.6 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 37.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
1.9 42.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
1.7 31.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
1.4 7.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
1.0 41.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.9 8.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.9 11.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.7 35.6 PID INSULIN PATHWAY Insulin Pathway
0.5 5.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.5 24.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.5 19.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.4 11.7 PID SHP2 PATHWAY SHP2 signaling
0.4 20.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.3 5.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 9.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 4.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.3 24.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 12.7 PID AP1 PATHWAY AP-1 transcription factor network
0.3 5.8 PID ARF 3PATHWAY Arf1 pathway
0.2 9.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 5.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 2.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 2.9 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 5.0 PID NOTCH PATHWAY Notch signaling pathway
0.1 6.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.8 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 101.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
5.3 90.5 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
4.5 86.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
4.4 62.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
3.8 26.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
3.7 36.5 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
3.6 25.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
3.1 33.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
2.1 29.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
2.0 26.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
2.0 24.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
1.8 40.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
1.8 12.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
1.7 11.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.4 16.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.9 13.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.9 21.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.9 12.8 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.8 16.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.7 19.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.7 14.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.6 28.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.6 9.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.5 5.5 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.5 6.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.5 4.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.4 13.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.4 13.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.4 3.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.3 5.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.3 25.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 8.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 10.9 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.2 10.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 8.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 7.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 14.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 7.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 3.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 4.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 5.1 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 3.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis