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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for mecom

Z-value: 0.71

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Transcription factors associated with mecom

Gene Symbol Gene ID Gene Info
mecom
ENSDARG00000060808 MDS1 and EVI1 complex locus

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mecomdr11_v1_chr15_-_35410860_35410860-0.422.9e-05Click!

Activity profile of mecom motif

Sorted Z-values of mecom motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_61203203 10.18 ENSDART00000171787
pvalb1
parvalbumin 1
chr15_+_22311803 5.50 ENSDART00000150182
hepacama
hepatic and glial cell adhesion molecule a
chr17_-_125091 5.32 ENSDART00000158825
actc1b
actin, alpha, cardiac muscle 1b
chr3_-_32817274 5.20 ENSDART00000142582
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr1_+_31110817 4.82 ENSDART00000137863
eef1a1b
eukaryotic translation elongation factor 1 alpha 1b
chr14_+_35691889 4.75 ENSDART00000074685
glrbb
glycine receptor, beta b
chr1_-_45553602 4.33 ENSDART00000143664
grin2bb
glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b
chr3_+_32443395 4.08 ENSDART00000188447
prr12b
proline rich 12b
chr6_-_40697585 3.94 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr24_-_15648636 3.91 ENSDART00000136200
cbln2b
cerebellin 2b precursor
chr10_-_31782616 3.77 ENSDART00000128839
fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr2_-_44283554 3.61 ENSDART00000184684
mpz
myelin protein zero
chr22_-_29242347 3.51 ENSDART00000040761
pvalb7
parvalbumin 7
chr15_-_23647078 3.23 ENSDART00000059366
ckmb
creatine kinase, muscle b
chr1_+_9071324 3.21 ENSDART00000184194
BX004779.2

chr18_-_21271373 3.05 ENSDART00000060001
pnp6
purine nucleoside phosphorylase 6
chr23_+_44745317 3.01 ENSDART00000165654
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr11_-_37509001 2.90 ENSDART00000109753
bsnb
bassoon (presynaptic cytomatrix protein) b
chr10_+_22012389 2.87 ENSDART00000035188
kcnip1b
Kv channel interacting protein 1 b
chr2_+_2563192 2.80 ENSDART00000055713
CABZ01033000.1

chr22_+_11535131 2.73 ENSDART00000113930
npb
neuropeptide B
chr19_+_16222618 2.72 ENSDART00000137189
ENSDART00000169246
ENSDART00000190583
ENSDART00000189521
ptprua
protein tyrosine phosphatase, receptor type, U, a
chr20_-_34801181 2.68 ENSDART00000048375
ENSDART00000132426
stmn4
stathmin-like 4
chr16_-_52879741 2.63 ENSDART00000166470
TPPP
tubulin polymerization promoting protein
chr7_-_38612230 2.55 ENSDART00000173678
c1qtnf4
C1q and TNF related 4
chr11_+_39672874 2.53 ENSDART00000046663
ENSDART00000157659
camta1b
calmodulin binding transcription activator 1b
chr6_-_50203682 2.52 ENSDART00000083999
ENSDART00000143050
raly
RALY heterogeneous nuclear ribonucleoprotein
chr4_+_26628822 2.51 ENSDART00000191030
ENSDART00000186113
ENSDART00000186764
ENSDART00000165158
iqsec3a
IQ motif and Sec7 domain 3a
chr9_+_29585943 2.47 ENSDART00000185989
ENSDART00000115290
mcf2lb
mcf.2 cell line derived transforming sequence-like b
chr9_+_13714379 2.36 ENSDART00000017593
ENSDART00000145503
tmem237a
transmembrane protein 237a
chr21_+_21326038 2.32 ENSDART00000089898
qpctlb
glutaminyl-peptide cyclotransferase-like b
chr12_-_6551681 2.20 ENSDART00000145413
si:ch211-253p2.2
si:ch211-253p2.2
chr21_+_5209716 2.19 ENSDART00000102539
ENSDART00000053148
ENSDART00000102536
st8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr11_+_35364445 2.17 ENSDART00000125766
camkvb
CaM kinase-like vesicle-associated b
chr15_+_33991928 2.16 ENSDART00000170177
vwde
von Willebrand factor D and EGF domains
chr2_+_29976419 2.10 ENSDART00000056748
en2b
engrailed homeobox 2b
chr9_-_9348058 2.09 ENSDART00000132257
zgc:113337
zgc:113337
chr3_+_37824268 2.06 ENSDART00000137038
asic2
acid-sensing (proton-gated) ion channel 2
chr17_+_33495194 2.04 ENSDART00000033691
pth2
parathyroid hormone 2
chr9_+_31534601 2.04 ENSDART00000133094
si:ch211-168k14.2
si:ch211-168k14.2
chr14_-_2187202 2.03 ENSDART00000160205
pcdh2ab12
protocadherin 2 alpha b 12
chr13_-_11644806 2.01 ENSDART00000169953
dctn1b
dynactin 1b
chr16_+_12836143 1.94 ENSDART00000067741
cacng6b
calcium channel, voltage-dependent, gamma subunit 6b
chr22_+_33362552 1.91 ENSDART00000101580
nicn1
nicolin 1
chr16_+_30959423 1.89 ENSDART00000136824
gstk2
glutathione S-transferase kappa 2
chr11_-_23322182 1.86 ENSDART00000111289
kiss1
KiSS-1 metastasis-suppressor
chr22_-_15385442 1.86 ENSDART00000090975
tmem264
transmembrane protein 264
chr16_+_7662609 1.85 ENSDART00000184895
ENSDART00000149404
ENSDART00000081418
ENSDART00000081422
bves
blood vessel epicardial substance
chr13_+_10232695 1.83 ENSDART00000080805
six2a
SIX homeobox 2a
chr9_+_1138323 1.83 ENSDART00000190352
ENSDART00000190387
slc15a1a
solute carrier family 15 (oligopeptide transporter), member 1a
chr22_+_8800432 1.82 ENSDART00000139940
si:dkey-182g1.6
si:dkey-182g1.6
chr7_+_10351038 1.81 ENSDART00000173256
si:cabz01029535.1
si:cabz01029535.1
chr19_+_17259912 1.80 ENSDART00000078951
MANEAL
si:ch211-30b16.2
chr6_-_6423885 1.79 ENSDART00000092257
si:ch211-194e18.2
si:ch211-194e18.2
chr1_+_37752171 1.78 ENSDART00000183247
ENSDART00000189756
ENSDART00000139448
GALNTL6
si:ch211-15e22.3
chr25_+_25438165 1.74 ENSDART00000161369
LRRC56
si:ch211-103e16.5
chr9_+_38983895 1.69 ENSDART00000144893
map2
microtubule-associated protein 2
chr16_+_14029283 1.68 ENSDART00000146165
ENSDART00000132075
rusc1
RUN and SH3 domain containing 1
chr9_+_10014817 1.67 ENSDART00000132065
nxph2a
neurexophilin 2a
chr14_+_22591624 1.65 ENSDART00000108987
gfra4b
GDNF family receptor alpha 4b
chr17_-_42213822 1.65 ENSDART00000187904
ENSDART00000180029
nkx2.2a
NK2 homeobox 2a
chr15_-_8517555 1.63 ENSDART00000140213
npas1
neuronal PAS domain protein 1
chr21_-_12119711 1.61 ENSDART00000131538
celf4
CUGBP, Elav-like family member 4
chr1_+_33383971 1.61 ENSDART00000150043
dhrsx
dehydrogenase/reductase (SDR family) X-linked
chr5_-_10946232 1.60 ENSDART00000163139
ENSDART00000031265
rtn4r
reticulon 4 receptor
chr7_-_38340674 1.59 ENSDART00000075782
slc7a10a
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10a
chr15_+_16908085 1.58 ENSDART00000186870
ypel2b
yippee-like 2b
chr6_-_39765546 1.56 ENSDART00000185767
pfkmb
phosphofructokinase, muscle b
chr21_+_15704556 1.56 ENSDART00000024858
ENSDART00000146909
chchd10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr6_-_46861676 1.56 ENSDART00000188712
ENSDART00000190148
igfn1.3
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr24_-_30096666 1.54 ENSDART00000183285
plppr4b
phospholipid phosphatase related 4b
chr17_+_26981132 1.52 ENSDART00000156672
si:dkey-221l4.11
si:dkey-221l4.11
chr3_-_33437796 1.52 ENSDART00000075499
si:dkey-283b1.7
si:dkey-283b1.7
chr18_-_6633984 1.50 ENSDART00000185241
tnni1c
troponin I, skeletal, slow c
chr16_+_36126310 1.50 ENSDART00000166040
ENSDART00000189802
sh3bp5b
SH3-domain binding protein 5b (BTK-associated)
chr9_+_48455909 1.50 ENSDART00000167243
lrp2a
low density lipoprotein receptor-related protein 2a
chr22_+_10752787 1.50 ENSDART00000186542
lsm7
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr4_-_27398385 1.50 ENSDART00000142117
ENSDART00000150553
ENSDART00000182746
fam19a5a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr24_+_26276805 1.49 ENSDART00000089749
adipoqa
adiponectin, C1Q and collagen domain containing, a
chr2_-_1188707 1.47 ENSDART00000066378
CABZ01084564.1

chr13_-_39830999 1.47 ENSDART00000115089
zgc:171482
zgc:171482
chr23_-_30781875 1.43 ENSDART00000114628
ENSDART00000180949
ENSDART00000191313
myt1a
myelin transcription factor 1a
chr24_+_41915878 1.41 ENSDART00000171523
TMEM200C
transmembrane protein 200C
chr11_-_3343463 1.39 ENSDART00000066177
tuba2
tubulin, alpha 2
chr10_-_15672862 1.39 ENSDART00000109231
mamdc2b
MAM domain containing 2b
chr8_+_48801402 1.38 ENSDART00000098363
tprg1l
tumor protein p63 regulated 1-like
chr5_-_31926906 1.37 ENSDART00000187340
ssh1b
slingshot protein phosphatase 1b
chr9_+_10014514 1.35 ENSDART00000185590
nxph2a
neurexophilin 2a
chr2_+_38554260 1.33 ENSDART00000171527
cdh24b
cadherin 24, type 2b
chr22_+_10752511 1.33 ENSDART00000081188
lsm7
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr17_+_29348013 1.31 ENSDART00000188885
ENSDART00000192005
ENSDART00000190484
ENSDART00000188565
kctd3
potassium channel tetramerization domain containing 3
chr22_+_8799855 1.30 ENSDART00000078235
si:dkey-182g1.6
si:dkey-182g1.6
chr5_+_44190974 1.29 ENSDART00000182634
ENSDART00000190626
TMEM8B
si:dkey-84j12.1
chr13_+_12174937 1.29 ENSDART00000171683
gabrg1
gamma-aminobutyric acid type A receptor gamma1 subunit
chr5_-_5147041 1.29 ENSDART00000180236
lmx1ba
LIM homeobox transcription factor 1, beta a
chr22_-_37565348 1.28 ENSDART00000149482
ENSDART00000104478
fxr1
fragile X mental retardation, autosomal homolog 1
chr23_+_35969228 1.26 ENSDART00000179992
ENSDART00000184107
hoxc10a
homeobox C10a
chr10_-_30785501 1.25 ENSDART00000020054
opcml
opioid binding protein/cell adhesion molecule-like
chr10_-_5581487 1.25 ENSDART00000141943
syk
spleen tyrosine kinase
chr24_+_25471196 1.25 ENSDART00000066625
smpx
small muscle protein, X-linked
chr12_-_29301022 1.23 ENSDART00000187826
sh2d4bb
SH2 domain containing 4Bb
chr19_+_42693855 1.23 ENSDART00000136873
clasp2
cytoplasmic linker associated protein 2
chr17_+_13763425 1.23 ENSDART00000105175
lrfn5a
leucine rich repeat and fibronectin type III domain containing 5a
chr2_-_1548330 1.22 ENSDART00000082155
ENSDART00000108481
ENSDART00000111272
dab1b
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr25_-_16782394 1.22 ENSDART00000019413
ndufa9a
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9a
chr7_-_17028015 1.21 ENSDART00000022441
dbx1a
developing brain homeobox 1a
chr9_-_1986014 1.21 ENSDART00000142842
hoxd12a
homeobox D12a
chr2_-_10188598 1.21 ENSDART00000189122
dmbx1a
diencephalon/mesencephalon homeobox 1a
chr1_+_38758261 1.20 ENSDART00000182756
wdr17
WD repeat domain 17
chr21_+_41743493 1.20 ENSDART00000192669
ppp2r2bb
protein phosphatase 2, regulatory subunit B, beta b
chr13_+_29771463 1.19 ENSDART00000134424
ENSDART00000138332
ENSDART00000134330
ENSDART00000160944
ENSDART00000076992
ENSDART00000160921
pax2a
paired box 2a
chr9_+_2002701 1.19 ENSDART00000082329
evx2
even-skipped homeobox 2
chr2_-_3678029 1.17 ENSDART00000146861
mmp16b
matrix metallopeptidase 16b (membrane-inserted)
chr7_+_21887307 1.16 ENSDART00000052871
pop7
POP7 homolog, ribonuclease P/MRP subunit
chr1_+_38758445 1.16 ENSDART00000136300
wdr17
WD repeat domain 17
chr11_+_42633376 1.15 ENSDART00000076711
appl1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr4_-_12104421 1.11 ENSDART00000139561
mrps33
mitochondrial ribosomal protein S33
chr21_-_43398457 1.10 ENSDART00000166530
ccni2
cyclin I family, member 2
chr1_+_34181581 1.10 ENSDART00000146042
epha6
eph receptor A6
chr12_+_38774860 1.09 ENSDART00000130371
kif19
kinesin family member 19
chr14_+_33722950 1.07 ENSDART00000075312
apln
apelin
chr6_-_29195642 1.06 ENSDART00000078625
dpt
dermatopontin
chr24_-_31843173 1.06 ENSDART00000185782
steap2
STEAP family member 2, metalloreductase
chr9_+_1137430 1.04 ENSDART00000187062
slc15a1a
solute carrier family 15 (oligopeptide transporter), member 1a
chr25_+_25438322 1.03 ENSDART00000150364
LRRC56
si:ch211-103e16.5
chr11_-_37359416 1.01 ENSDART00000159184
erc2
ELKS/RAB6-interacting/CAST family member 2
chr20_+_38322444 1.01 ENSDART00000161741
ENSDART00000132241
ENSDART00000148936
ENSDART00000149623
stum
stum, mechanosensory transduction mediator homolog
chr19_+_19511394 0.99 ENSDART00000172410
jazf1a
JAZF zinc finger 1a
chr18_+_16330025 0.99 ENSDART00000142353
nts
neurotensin
chr25_-_12935065 0.98 ENSDART00000167362
ccl39.7
chemokine (C-C motif) ligand 39, duplicate 7
chr16_+_19014886 0.98 ENSDART00000079298
si:ch211-254p10.2
si:ch211-254p10.2
chr2_+_15776649 0.98 ENSDART00000156535
vav3b
vav 3 guanine nucleotide exchange factor b
chr3_-_18274691 0.96 ENSDART00000161140
BX649434.3

chr14_-_32089117 0.96 ENSDART00000158014
si:ch211-69b22.5
si:ch211-69b22.5
chr3_+_1637358 0.94 ENSDART00000180266
CR394546.5

chr25_+_33002963 0.93 ENSDART00000187366
CABZ01046980.1

chr2_-_51290607 0.90 ENSDART00000171693
si:ch211-215e19.3
si:ch211-215e19.3
chr4_-_8902406 0.88 ENSDART00000192962
mpped1
metallophosphoesterase domain containing 1
chr6_-_25181012 0.88 ENSDART00000161585
lrrc8db
leucine rich repeat containing 8 VRAC subunit Db
chr15_+_19646902 0.88 ENSDART00000179822
lim2.3
lens intrinsic membrane protein 2.3
chr13_+_30172645 0.87 ENSDART00000137114
pald1b
phosphatase domain containing, paladin 1b
chr3_+_32789605 0.86 ENSDART00000171895
tbc1d10b
TBC1 domain family, member 10b
chr14_-_30141162 0.85 ENSDART00000053916
mtnr1ab
melatonin receptor 1A b
chr25_-_12935424 0.84 ENSDART00000160217
ccl39.7
chemokine (C-C motif) ligand 39, duplicate 7
chr15_+_5028608 0.84 ENSDART00000092809
abcg1
ATP-binding cassette, sub-family G (WHITE), member 1
chr9_-_18742704 0.82 ENSDART00000145401
tsc22d1
TSC22 domain family, member 1
chr24_-_26304386 0.81 ENSDART00000175416
otos
otospiralin
chr16_+_10972733 0.79 ENSDART00000049323
pou2f2a
POU class 2 homeobox 2a
chr4_+_54618332 0.79 ENSDART00000171824
si:ch211-227e10.2
si:ch211-227e10.2
chr20_+_1996202 0.78 ENSDART00000184143
CABZ01092781.1

chr10_+_34394454 0.78 ENSDART00000110121
stard13a
StAR-related lipid transfer (START) domain containing 13a
chr15_+_28119704 0.78 ENSDART00000184290
unc119a
unc-119 homolog a (C. elegans)
chr18_-_28938912 0.76 ENSDART00000136201
si:ch211-174j14.2
si:ch211-174j14.2
chr10_+_21899753 0.76 ENSDART00000080155
hrh2b
histamine receptor H2b
chr6_-_31806345 0.74 ENSDART00000149369
si:dkey-209n16.2
si:dkey-209n16.2
chr6_+_8176486 0.74 ENSDART00000193308
nfil3-5
nuclear factor, interleukin 3 regulated, member 5
chr23_+_20110086 0.74 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr12_+_23912074 0.73 ENSDART00000152864
svila
supervillin a
chr12_+_2428247 0.73 ENSDART00000152529
lrrc18b
leucine rich repeat containing 18b
chr23_+_30835589 0.72 ENSDART00000154145
npbwr2a
neuropeptides B/W receptor 2a
chr1_-_36771712 0.72 ENSDART00000148386
prmt9
protein arginine methyltransferase 9
chr7_+_38395197 0.71 ENSDART00000138669
cep89
centrosomal protein 89
chr1_-_33351780 0.71 ENSDART00000178996
gyg2
glycogenin 2
chr6_-_29051773 0.70 ENSDART00000190508
ENSDART00000180191
ENSDART00000111682
evi5b
ecotropic viral integration site 5b
chr15_-_8517376 0.69 ENSDART00000186289
npas1
neuronal PAS domain protein 1
chr18_+_16246806 0.68 ENSDART00000142584
alx1
ALX homeobox 1
chr5_+_19165949 0.68 ENSDART00000140710
unc13ba
unc-13 homolog Ba (C. elegans)
chr13_-_39830816 0.67 ENSDART00000138981
zgc:171482
zgc:171482
chr3_+_24511959 0.66 ENSDART00000133898
dnal4a
dynein, axonemal, light chain 4a
chr21_+_30043054 0.65 ENSDART00000065448
fabp6
fatty acid binding protein 6, ileal (gastrotropin)
chr4_-_39110934 0.65 ENSDART00000185041
si:dkey-122c11.8
si:dkey-122c11.8
chr19_-_36401282 0.65 ENSDART00000193856
csmd2
CUB and Sushi multiple domains 2
chr24_-_5889878 0.65 ENSDART00000077951
pcolce2b
procollagen C-endopeptidase enhancer 2b
chr24_-_26460853 0.64 ENSDART00000078628
slc7a14b
solute carrier family 7, member 14b
chr6_-_10964083 0.64 ENSDART00000181583
notum2
notum pectinacetylesterase 2
chr11_-_41130239 0.64 ENSDART00000173268
dnajc11b
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr20_+_48803248 0.64 ENSDART00000164006
nkx2.4b
NK2 homeobox 4b
chr19_+_27342479 0.63 ENSDART00000184687
ddx39b
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr6_+_43390387 0.63 ENSDART00000122793
mitfa
microphthalmia-associated transcription factor a
chr12_-_32426685 0.63 ENSDART00000105574
enpp7.2
ectonucleotide pyrophosphatase/phosphodiesterase 7, tandem duplicate 2
chr3_-_147368 0.60 ENSDART00000159073
CR391944.1

chr7_-_8374950 0.59 ENSDART00000057101
aep1
aerolysin-like protein
chr6_+_46259950 0.59 ENSDART00000032326
zgc:162324
zgc:162324
chr5_-_18046053 0.59 ENSDART00000144898
rnf215
ring finger protein 215
chr6_-_25180438 0.58 ENSDART00000159696
lrrc8db
leucine rich repeat containing 8 VRAC subunit Db
chr2_+_17540720 0.58 ENSDART00000114638
pimr198
Pim proto-oncogene, serine/threonine kinase, related 198
chr15_+_6774994 0.58 ENSDART00000170011
si:ch1073-228b5.2
si:ch1073-228b5.2
chr10_-_22854758 0.57 ENSDART00000079449
and3
actinodin3
chr7_+_5541747 0.56 ENSDART00000144876
si:dkeyp-67a8.4
si:dkeyp-67a8.4
chr23_+_19213472 0.56 ENSDART00000185985
apobec2b
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2b
chr24_+_31348595 0.55 ENSDART00000160140
ENSDART00000158661
cremb
cAMP responsive element modulator b
chr18_-_6634424 0.54 ENSDART00000062423
ENSDART00000179955
tnni1c
troponin I, skeletal, slow c
chr22_-_17256573 0.53 ENSDART00000136119
ENSDART00000062891
nphs2
nephrosis 2, idiopathic, steroid-resistant (podocin)
chr13_+_18514788 0.53 ENSDART00000124036
tlr4ba
toll-like receptor 4b, duplicate a
chr5_-_5147220 0.53 ENSDART00000187026
ENSDART00000162334
lmx1ba
LIM homeobox transcription factor 1, beta a
chr25_-_1235457 0.52 ENSDART00000093093
coro2bb
coronin, actin binding protein, 2Bb
chr25_-_4235037 0.52 ENSDART00000093003
syt7a
synaptotagmin VIIa
chr23_-_20154422 0.52 ENSDART00000132025
usp19
ubiquitin specific peptidase 19
chr1_+_22002649 0.52 ENSDART00000141317
dnah6
dynein, axonemal, heavy chain 6
chr14_-_47963115 0.51 ENSDART00000003826
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2

Network of associatons between targets according to the STRING database.

First level regulatory network of mecom

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.5 1.6 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.5 1.6 GO:0042942 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.4 1.2 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.4 1.2 GO:1901006 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.4 2.0 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.4 1.9 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.3 2.9 GO:0006857 oligopeptide transport(GO:0006857)
0.3 4.7 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.3 2.9 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.3 1.1 GO:0015677 copper ion import(GO:0015677)
0.2 3.2 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.2 4.3 GO:0099565 excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
0.2 0.8 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.2 0.8 GO:1990697 protein depalmitoleylation(GO:1990697)
0.2 1.5 GO:0070293 renal absorption(GO:0070293)
0.2 0.6 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.2 1.1 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.2 0.5 GO:0071312 response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
0.2 3.0 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.2 3.1 GO:0014823 response to activity(GO:0014823)
0.2 1.2 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.2 1.8 GO:0021592 fourth ventricle development(GO:0021592)
0.1 1.2 GO:0021588 cerebellum formation(GO:0021588)
0.1 1.6 GO:0061620 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.7 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 1.0 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 1.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.5 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.1 0.7 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.1 1.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.4 GO:0070255 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.1 2.7 GO:0007631 feeding behavior(GO:0007631)
0.1 0.8 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 2.2 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.3 GO:0060078 regulation of postsynaptic membrane potential(GO:0060078)
0.1 1.0 GO:1990709 presynaptic active zone organization(GO:1990709)
0.1 1.9 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.1 2.0 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 4.8 GO:0006414 translational elongation(GO:0006414)
0.1 0.4 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.5 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011)
0.1 1.6 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 3.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.2 GO:0061074 regulation of neural retina development(GO:0061074)
0.1 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.2 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 2.7 GO:1902749 regulation of cell cycle G2/M phase transition(GO:1902749)
0.1 0.2 GO:0046436 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.1 2.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.9 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 1.9 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 1.2 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.3 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 0.2 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.6 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.9 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.6 GO:0042407 cristae formation(GO:0042407)
0.0 0.7 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 1.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.8 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.5 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.7 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 2.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.4 GO:0030901 midbrain development(GO:0030901)
0.0 0.5 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 0.8 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.0 1.1 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.5 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 1.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.3 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.5 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.6 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.6 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.7 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 2.2 GO:0021782 glial cell development(GO:0021782)
0.0 0.5 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.6 GO:0034332 adherens junction organization(GO:0034332)
0.0 0.6 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.6 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.5 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 2.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.8 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.3 5.3 GO:0005869 dynactin complex(GO:0005869)
0.3 1.3 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.3 3.0 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.3 2.9 GO:0098982 GABA-ergic synapse(GO:0098982)
0.3 4.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 1.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 1.2 GO:0043034 costamere(GO:0043034)
0.2 3.6 GO:0043209 myelin sheath(GO:0043209)
0.1 1.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.0 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.0 GO:0035371 microtubule plus-end(GO:0035371)
0.1 3.2 GO:0005861 troponin complex(GO:0005861)
0.1 2.5 GO:0035869 ciliary transition zone(GO:0035869)
0.1 1.7 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.1 0.5 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 0.6 GO:0061617 MICOS complex(GO:0061617)
0.1 1.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 1.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.3 GO:0016342 catenin complex(GO:0016342)
0.0 1.6 GO:0030286 dynein complex(GO:0030286)
0.0 0.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 4.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.6 GO:0046930 pore complex(GO:0046930)
0.0 1.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.5 GO:0070822 Sin3-type complex(GO:0070822)
0.0 2.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 5.0 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.7 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 2.3 GO:0005874 microtubule(GO:0005874)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.5 4.7 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.4 2.9 GO:0042936 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.4 1.1 GO:0031704 apelin receptor binding(GO:0031704)
0.3 3.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 2.0 GO:0004630 phospholipase D activity(GO:0004630)
0.3 2.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 1.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 3.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.2 3.9 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.2 4.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.2 0.8 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.2 0.6 GO:0048030 disaccharide binding(GO:0048030)
0.2 1.9 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.2 2.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 0.5 GO:0016496 substance P receptor activity(GO:0016496)
0.2 2.0 GO:0048018 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.2 0.5 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.2 3.0 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.8 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.4 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.1 0.5 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.5 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.7 GO:0032052 bile acid binding(GO:0032052)
0.1 1.0 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 1.8 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1 4.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.8 GO:0030552 cAMP binding(GO:0030552)
0.1 1.6 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 3.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 0.7 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.7 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.8 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.1 1.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.2 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.1 0.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 1.5 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 0.5 GO:0052743 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659) inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0 1.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.3 GO:0015250 water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 1.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 2.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.5 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 1.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.7 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 1.3 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 1.5 GO:0042562 hormone binding(GO:0042562)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 1.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 4.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.5 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 4.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 1.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.5 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 3.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.9 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 0.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 2.1 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer