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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for mef2aa+mef2ab

Z-value: 2.89

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Transcription factors associated with mef2aa+mef2ab

Gene Symbol Gene ID Gene Info
mef2aa
ENSDARG00000031756 myocyte enhancer factor 2aa
mef2ab
ENSDARG00000057527 myocyte enhancer factor 2ab
mef2ab
ENSDARG00000110771 myocyte enhancer factor 2ab

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mef2aadr11_v1_chr18_+_23249519_232495190.807.2e-22Click!
mef2abdr11_v1_chr7_+_15677196_156771960.232.4e-02Click!

Activity profile of mef2aa+mef2ab motif

Sorted Z-values of mef2aa+mef2ab motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_61205711 78.08 ENSDART00000055062
pvalb1
parvalbumin 1
chr25_+_31264155 68.42 ENSDART00000012256
tnni2a.3
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr3_+_32526263 60.37 ENSDART00000150897
si:ch73-367p23.2
si:ch73-367p23.2
chr12_-_26064105 58.95 ENSDART00000168825
ldb3b
LIM domain binding 3b
chr5_-_72125551 52.59 ENSDART00000149412
smyd1a
SET and MYND domain containing 1a
chr21_+_20383837 51.01 ENSDART00000026430
hspb11
heat shock protein, alpha-crystallin-related, b11
chr6_-_18199062 49.70 ENSDART00000167513
ppp1r27b
protein phosphatase 1, regulatory subunit 27b
chr8_-_11112058 47.93 ENSDART00000042755
ampd1
adenosine monophosphate deaminase 1 (isoform M)
chr12_-_17712393 46.75 ENSDART00000143534
ENSDART00000010144
pvalb2
parvalbumin 2
chr7_+_7048245 46.75 ENSDART00000001649
actn3b
actinin alpha 3b
chr16_+_29663809 44.46 ENSDART00000191336
tmod4
tropomodulin 4 (muscle)
chr19_-_7450796 42.76 ENSDART00000104750
mllt11
MLLT11, transcription factor 7 cofactor
chr12_-_26064480 41.96 ENSDART00000158215
ENSDART00000171206
ENSDART00000171212
ENSDART00000182956
ENSDART00000186779
ldb3b
LIM domain binding 3b
chr1_+_7546259 40.42 ENSDART00000015732
mylz3
myosin, light polypeptide 3, skeletal muscle
chr5_+_51597677 40.31 ENSDART00000048210
ENSDART00000184797
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr7_+_6969909 37.23 ENSDART00000189886
actn3b
actinin alpha 3b
chr14_+_49296052 35.07 ENSDART00000006073
ENSDART00000105346
anxa6
annexin A6
chr16_+_25245857 30.80 ENSDART00000155220
klhl38b
kelch-like family member 38b
chr24_+_34089977 29.69 ENSDART00000157466
asb10
ankyrin repeat and SOCS box containing 10
chr9_-_42873700 29.47 ENSDART00000125953
ttn.1
titin, tandem duplicate 1
chr11_+_11200550 29.17 ENSDART00000181339
ENSDART00000187116
myom2a
myomesin 2a
chr17_-_5583345 28.96 ENSDART00000035944
clic5a
chloride intracellular channel 5a
chr6_+_14301214 28.60 ENSDART00000129491
tmem182b
transmembrane protein 182b
chr20_-_26001288 28.28 ENSDART00000136518
ENSDART00000063177
capn3b
calpain 3b
chr5_+_64368770 27.49 ENSDART00000162246
plpp7
phospholipid phosphatase 7 (inactive)
chr13_-_2215213 27.32 ENSDART00000129773
mlip
muscular LMNA-interacting protein
chr3_-_52614747 26.97 ENSDART00000154365
trim35-13
tripartite motif containing 35-13
chr23_+_20110086 26.57 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr13_+_22480857 26.47 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
ldb3a
LIM domain binding 3a
chr7_-_23745984 26.24 ENSDART00000048050
ITGB1BP2
zgc:92429
chr2_-_15324837 25.82 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr12_+_6002715 25.58 ENSDART00000114961
si:ch211-131k2.3
si:ch211-131k2.3
chr1_+_6171585 24.88 ENSDART00000024358
prkag3a
protein kinase, AMP-activated, gamma 3a non-catalytic subunit
chr7_+_69841017 24.46 ENSDART00000169107
FO818704.1

chr25_+_20077225 24.30 ENSDART00000136543
tnni4b.1
troponin I4b, tandem duplicate 1
chr11_-_18253111 24.24 ENSDART00000125984
mustn1b
musculoskeletal, embryonic nuclear protein 1b
chr5_-_57635664 24.00 ENSDART00000074306
hspb2
heat shock protein, alpha-crystallin-related, b2
chr18_+_26719787 23.87 ENSDART00000141672
alpk3a
alpha-kinase 3a
chr15_+_5923851 23.47 ENSDART00000152520
ENSDART00000145827
ENSDART00000121529
sh3bgr
SH3 domain binding glutamate-rich protein
chr14_+_22113331 22.35 ENSDART00000109759
tmx2a
thioredoxin-related transmembrane protein 2a
chr19_-_33087246 20.95 ENSDART00000052078
klhl38a
kelch-like family member 38a
chr16_-_43356018 20.73 ENSDART00000181683
FO704821.1

chr8_-_11229523 19.87 ENSDART00000002164
unc45b
unc-45 myosin chaperone B
chr23_+_6077503 19.80 ENSDART00000081714
ENSDART00000139834
mybpha
myosin binding protein Ha
chr19_-_31035155 19.25 ENSDART00000161882
bzw2
basic leucine zipper and W2 domains 2
chr25_+_14087045 19.25 ENSDART00000155770
actc1c
actin, alpha, cardiac muscle 1c
chr23_+_24926407 19.10 ENSDART00000137486
klhl21
kelch-like family member 21
chr21_-_131236 19.10 ENSDART00000160005
si:ch1073-398f15.1
si:ch1073-398f15.1
chr25_-_23745765 18.36 ENSDART00000089278
si:ch211-236l14.4
si:ch211-236l14.4
chr16_-_17200120 18.22 ENSDART00000147739
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr19_-_31035325 18.09 ENSDART00000147504
bzw2
basic leucine zipper and W2 domains 2
chr24_+_9298198 16.89 ENSDART00000165780
otud1
OTU deubiquitinase 1
chr9_-_23891102 16.67 ENSDART00000186799
asb18
ankyrin repeat and SOCS box containing 18
chr17_-_14671098 16.63 ENSDART00000037371
ppp1r13ba
protein phosphatase 1, regulatory subunit 13Ba
chr6_-_20875111 16.25 ENSDART00000115118
ENSDART00000159916
tns1a
tensin 1a
chr21_-_27507786 15.75 ENSDART00000077657
ENSDART00000191284
ENSDART00000178229
ENSDART00000186153
CAPN1
si:dkeyp-50d11.2
chr20_+_34455645 15.11 ENSDART00000135789
mettl11b
methyltransferase like 11B
chr24_+_25471196 15.02 ENSDART00000066625
smpx
small muscle protein, X-linked
chr19_+_30990815 14.86 ENSDART00000134645
sync
syncoilin, intermediate filament protein
chr8_-_26388090 14.78 ENSDART00000147912
si:dkey-20d21.12
si:dkey-20d21.12
chr3_-_32170850 14.66 ENSDART00000055307
ENSDART00000157366
tnnt1
troponin T type 1 (skeletal, slow)
chr1_-_11075403 12.64 ENSDART00000102903
ENSDART00000170290
dmd
dystrophin
chr5_-_48260145 12.42 ENSDART00000044083
ENSDART00000163250
ENSDART00000135911
mef2cb
myocyte enhancer factor 2cb
chr18_+_23193567 12.31 ENSDART00000190072
ENSDART00000171594
ENSDART00000181762
mef2aa
myocyte enhancer factor 2aa
chr6_+_12462079 12.20 ENSDART00000192029
ENSDART00000065385
nr4a2b
nuclear receptor subfamily 4, group A, member 2b
chr3_+_28953274 12.14 ENSDART00000133528
ENSDART00000103602
lgals2a
lectin, galactoside-binding, soluble, 2a
chr9_+_54644626 11.95 ENSDART00000190609
egfl6
EGF-like-domain, multiple 6
chr23_+_17417539 11.55 ENSDART00000182605
BX649300.2

chr23_+_33907899 11.53 ENSDART00000159445
cs
citrate synthase
chr20_-_36575475 11.48 ENSDART00000062893
enah
enabled homolog (Drosophila)
chr12_-_4781801 11.40 ENSDART00000167490
ENSDART00000121718
mapta
microtubule-associated protein tau a
chr18_+_23193820 11.28 ENSDART00000148106
mef2aa
myocyte enhancer factor 2aa
chr11_-_40030139 11.15 ENSDART00000021916
uts2b
urotensin 2, beta
chr2_-_23768818 10.79 ENSDART00000148685
ENSDART00000191167
xirp1
xin actin binding repeat containing 1
chr15_-_22139566 10.72 ENSDART00000149017
scn3b
sodium channel, voltage-gated, type III, beta
chr25_+_11389220 10.53 ENSDART00000187787
AGBL1
si:ch73-141f14.1
chr7_-_19614916 10.45 ENSDART00000169029
zgc:194655
zgc:194655
chrM_+_4993 10.35 ENSDART00000093600
mt-nd2
NADH dehydrogenase 2, mitochondrial
chr24_+_38155830 9.75 ENSDART00000152019
si:ch211-234p6.5
si:ch211-234p6.5
chr11_-_33960318 9.53 ENSDART00000087597
col6a2
collagen, type VI, alpha 2
chr3_-_53114299 9.41 ENSDART00000109390
AL954361.1

chr1_-_35653560 9.40 ENSDART00000142154
frem3
Fras1 related extracellular matrix 3
chr7_-_22956889 9.14 ENSDART00000101447
tnfsf10l
TNF superfamily member 10, like
chr13_+_28821841 9.01 ENSDART00000179900
CU639469.1

chr9_-_43073960 8.96 ENSDART00000059460
ttn.2
titin, tandem duplicate 2
chr20_+_6756247 8.62 ENSDART00000167344
igfbp3
insulin-like growth factor binding protein 3
chr14_+_30328567 8.27 ENSDART00000105889
mtus1a
microtubule associated tumor suppressor 1a
chr12_-_19119176 8.26 ENSDART00000149180
aco2
aconitase 2, mitochondrial
chr8_-_32497815 8.06 ENSDART00000122359
si:dkey-164f24.2
si:dkey-164f24.2
chr16_-_31475904 8.04 ENSDART00000145691
si:ch211-251p5.5
si:ch211-251p5.5
chr3_-_50046004 7.86 ENSDART00000109544
si:ch1073-100f3.2
si:ch1073-100f3.2
chr23_+_32039386 7.84 ENSDART00000133801
mylk2
myosin light chain kinase 2
chr14_-_8795081 7.81 ENSDART00000106671
tgfb2l
transforming growth factor, beta 2, like
chr13_+_38817871 7.80 ENSDART00000187708
col19a1
collagen, type XIX, alpha 1
chr21_+_40589770 7.73 ENSDART00000164650
ENSDART00000161584
ENSDART00000161108
pdk3b
pyruvate dehydrogenase kinase, isozyme 3b
chr23_+_36601984 7.57 ENSDART00000128598
igfbp6b
insulin-like growth factor binding protein 6b
chr3_-_27915270 7.32 ENSDART00000115370
mettl22
methyltransferase like 22
chr16_+_34046733 7.26 ENSDART00000058424
fam46ba
family with sequence similarity 46, member Ba
chr5_+_69808763 7.25 ENSDART00000143482
fsd1l
fibronectin type III and SPRY domain containing 1-like
chr13_-_30149973 7.20 ENSDART00000041515
sar1ab
secretion associated, Ras related GTPase 1Ab
chrM_-_15232 7.16 ENSDART00000093623
mt-nd6
NADH dehydrogenase 6, mitochondrial
chr23_-_39849155 6.95 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr16_-_29164379 6.93 ENSDART00000132589
mef2d
myocyte enhancer factor 2d
chr14_-_46451249 6.89 ENSDART00000058466
fgfbp2a
fibroblast growth factor binding protein 2a
chr1_-_13271085 6.46 ENSDART00000193663
pcdh18a
protocadherin 18a
chr6_-_46768040 6.19 ENSDART00000154071
igfn1.2
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 2
chr5_-_8711157 6.15 ENSDART00000062957
paip1
poly(A) binding protein interacting protein 1
chr22_-_7006974 5.99 ENSDART00000133143
gpd1b
glycerol-3-phosphate dehydrogenase 1b
chr8_-_32497581 5.91 ENSDART00000176298
ENSDART00000183340
si:dkey-164f24.2
si:dkey-164f24.2
chr3_+_28939759 5.87 ENSDART00000141904
lgals1l1
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr10_-_17232372 5.86 ENSDART00000135679
rab36
RAB36, member RAS oncogene family
chr20_+_33532296 5.83 ENSDART00000153153
kcnf1a
potassium voltage-gated channel, subfamily F, member 1a
chr19_-_12648122 5.81 ENSDART00000151184
fam210aa
family with sequence similarity 210, member Aa
chr15_+_28940352 5.33 ENSDART00000154085
gipr
gastric inhibitory polypeptide receptor
chr1_-_13271569 5.24 ENSDART00000127838
pcdh18a
protocadherin 18a
chr6_-_10863582 5.21 ENSDART00000135454
ENSDART00000133893
ENSDART00000014521
ENSDART00000164342
lnpk
lunapark, ER junction formation factor
chr5_-_32505109 5.15 ENSDART00000188219
ntmt1
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr9_-_23990416 5.10 ENSDART00000113176
col6a3
collagen, type VI, alpha 3
chr16_-_17541890 5.09 ENSDART00000131328
clcn1b
chloride channel, voltage-sensitive 1b
chr18_-_16791331 4.94 ENSDART00000148222
ampd3b
adenosine monophosphate deaminase 3b
chr7_-_22956716 4.93 ENSDART00000122113
tnfsf10l
TNF superfamily member 10, like
chr8_-_18010735 4.78 ENSDART00000125014
acot11b
acyl-CoA thioesterase 11b
chr18_-_11184584 4.77 ENSDART00000040500
tspan9a
tetraspanin 9a
chr14_+_23518110 4.67 ENSDART00000112930
si:ch211-221f10.2
si:ch211-221f10.2
chr10_-_10607118 4.64 ENSDART00000101089
dbh
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr10_+_36345176 4.61 ENSDART00000099397
or105-1
odorant receptor, family C, subfamily 105, member 1
chr1_-_22652424 4.59 ENSDART00000036797
uchl1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr12_+_27537357 4.57 ENSDART00000136212
etv4
ets variant 4
chr12_+_18718065 4.45 ENSDART00000152935
mkl1b
megakaryoblastic leukemia (translocation) 1b
chr23_+_14097508 4.43 ENSDART00000087280
cacnb3a
calcium channel, voltage-dependent, beta 3a
chr5_-_32505276 4.36 ENSDART00000034705
ENSDART00000187597
ntmt1
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr7_+_39006837 4.29 ENSDART00000173735
dgkza
diacylglycerol kinase, zeta a
chr6_-_52234796 4.28 ENSDART00000001803
tomm34
translocase of outer mitochondrial membrane 34
chr17_+_5976683 4.27 ENSDART00000110276
zgc:194275
zgc:194275
chr22_-_8509215 4.27 ENSDART00000140146
si:ch73-27e22.3
si:ch73-27e22.3
chr14_+_23520986 4.25 ENSDART00000170473
ENSDART00000175970
si:ch211-221f10.2
si:ch211-221f10.2
chr7_-_44957503 4.24 ENSDART00000165077
cdh16
cadherin 16, KSP-cadherin
chr9_+_27876146 4.17 ENSDART00000133997
armc8
armadillo repeat containing 8
chr2_-_28102264 3.94 ENSDART00000013638
cdh6
cadherin 6
chr7_+_40093662 3.82 ENSDART00000053011
si:ch73-174h16.4
si:ch73-174h16.4
chr16_-_32837806 3.79 ENSDART00000003997
MCHR2
si:dkey-165n16.5
chr11_+_41560792 3.77 ENSDART00000127292
kcnab2a
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr1_+_33969015 3.69 ENSDART00000042984
ENSDART00000146530
epha6
eph receptor A6
chr16_-_32975951 3.64 ENSDART00000101969
ENSDART00000175149
me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr8_+_21159122 3.58 ENSDART00000033491
spryd4
SPRY domain containing 4
chr7_+_57677120 3.55 ENSDART00000110623
arsj
arylsulfatase family, member J
chr17_-_5769196 3.52 ENSDART00000113885
si:dkey-100n19.2
si:dkey-100n19.2
chr22_-_13649588 3.50 ENSDART00000131877
si:ch211-279g13.1
si:ch211-279g13.1
chr6_-_49873020 3.45 ENSDART00000148511
gnas
GNAS complex locus
chr18_+_10820430 3.43 ENSDART00000161990
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr15_+_15856178 3.40 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr21_-_39253647 3.38 ENSDART00000133034
tusc5b
tumor suppressor candidate 5b
chr1_-_8917902 3.32 ENSDART00000137900
grin2ab
glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b
chr25_-_6557854 3.21 ENSDART00000181740
cspg4
chondroitin sulfate proteoglycan 4
chr18_-_38087875 3.21 ENSDART00000111301
luzp2
leucine zipper protein 2
chr25_+_19105804 3.13 ENSDART00000104414
rlbp1b
retinaldehyde binding protein 1b
chr10_-_17501528 3.03 ENSDART00000144847
slc2a11l
solute carrier family 2 (facilitated glucose transporter), member 11-like
chr25_-_15245475 3.02 ENSDART00000142943
ccdc73
coiled-coil domain containing 73
chr16_-_16590489 2.92 ENSDART00000190021
si:ch211-257p13.3
si:ch211-257p13.3
chr16_-_36798783 2.88 ENSDART00000145697
calb1
calbindin 1
chr2_-_5356686 2.85 ENSDART00000124290
MFN1
mitofusin 1
chr5_-_64511428 2.83 ENSDART00000016321
rxrab
retinoid x receptor, alpha b
chr12_+_27141140 2.80 ENSDART00000136415
hoxb1b
homeobox B1b
chr24_-_27409599 2.77 ENSDART00000041770
ccl34b.3
chemokine (C-C motif) ligand 34b, duplicate 3
chr20_+_2134816 2.75 ENSDART00000039249
l3mbtl3
l(3)mbt-like 3 (Drosophila)
chr17_+_8184649 2.64 ENSDART00000091818
tulp4b
tubby like protein 4b
chr24_-_5691956 2.64 ENSDART00000189112
dia1b
deleted in autism 1b
chr1_-_45662774 2.61 ENSDART00000042158
serhl
serine hydrolase-like
chr17_-_16069905 2.54 ENSDART00000110383
map7a
microtubule-associated protein 7a
chr18_+_8339596 2.54 ENSDART00000183323
ENSDART00000185397
BX276107.1

chr12_-_6905375 2.51 ENSDART00000152322
pcdh15b
protocadherin-related 15b
chr12_-_20340543 2.50 ENSDART00000055623
hbbe3
hemoglobin beta embryonic-3
chr24_-_6647275 2.44 ENSDART00000161494
arhgap21a
Rho GTPase activating protein 21a
chr20_-_2134620 2.43 ENSDART00000064375
tmem244
transmembrane protein 244
chr10_+_41765616 2.42 ENSDART00000170682
rnf34b
ring finger protein 34b
chr25_+_3677650 2.34 ENSDART00000154348
prnprs3
prion protein, related sequence 3
chr2_-_36925561 2.28 ENSDART00000187690
map1sb
microtubule-associated protein 1Sb
chr20_+_812012 2.24 ENSDART00000179299
ENSDART00000137135
mei4
meiosis-specific, MEI4 homolog (S. cerevisiae)
chr2_-_3678029 2.17 ENSDART00000146861
mmp16b
matrix metallopeptidase 16b (membrane-inserted)
chr4_-_2719128 2.15 ENSDART00000184693
slco1c1
solute carrier organic anion transporter family, member 1C1
chr23_-_19953089 2.14 ENSDART00000153828
atp2b3b
ATPase plasma membrane Ca2+ transporting 3b
chr12_+_29236274 2.13 ENSDART00000006505
mxtx2
mix-type homeobox gene 2
chr1_+_20084389 2.06 ENSDART00000140263
prss12
protease, serine, 12 (neurotrypsin, motopsin)
chr13_-_33114933 2.06 ENSDART00000140543
ENSDART00000075953
zfyve26
zinc finger, FYVE domain containing 26
chr23_-_7797207 2.03 ENSDART00000181611
myt1b
myelin transcription factor 1b
chr17_-_23221504 2.02 ENSDART00000156411
fam98a
family with sequence similarity 98, member A
chr19_+_9091673 1.98 ENSDART00000052898
si:ch211-81a5.5
si:ch211-81a5.5
chr1_-_42778510 1.98 ENSDART00000190172
lrrtm1
leucine rich repeat transmembrane neuronal 1
chr5_+_24305877 1.96 ENSDART00000144226
ctsll
cathepsin L, like
chr2_+_35880600 1.95 ENSDART00000004277
lamc1
laminin, gamma 1
chr9_-_22188117 1.91 ENSDART00000132890
crygm2d17
crystallin, gamma M2d17
chr6_-_18698456 1.86 ENSDART00000166587
rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr20_+_6630540 1.85 ENSDART00000138361
tns3.2
tensin 3, tandem duplicate 2
chr23_-_27633730 1.84 ENSDART00000103639
arf3a
ADP-ribosylation factor 3a
chr17_-_34853229 1.83 ENSDART00000152033
kidins220a
kinase D-interacting substrate 220a
chr21_-_22910520 1.81 ENSDART00000065567
ENSDART00000191792
guca1d
guanylate cyclase activator 1d
chr6_-_894006 1.80 ENSDART00000171091
zeb2b
zinc finger E-box binding homeobox 2b
chr15_-_34668485 1.74 ENSDART00000186605
bag6
BCL2 associated athanogene 6
chr4_+_9279515 1.69 ENSDART00000048707
srgap1b
SLIT-ROBO Rho GTPase activating protein 1b
chr3_-_34100700 1.65 ENSDART00000151628
ighv6-1
immunoglobulin heavy variable 6-1

Network of associatons between targets according to the STRING database.

First level regulatory network of mef2aa+mef2ab

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.4 28.3 GO:0097264 self proteolysis(GO:0097264)
8.8 35.1 GO:0001778 plasma membrane repair(GO:0001778) chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
8.6 42.8 GO:0090200 regulation of mitochondrial membrane potential(GO:0051881) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
8.2 24.6 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
6.5 148.9 GO:0031033 myosin filament organization(GO:0031033)
4.8 24.2 GO:0035988 chondrocyte proliferation(GO:0035988)
4.4 39.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
3.8 11.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
3.7 52.2 GO:0032264 IMP salvage(GO:0032264)
3.1 40.3 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
2.9 14.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
2.8 119.3 GO:0003009 skeletal muscle contraction(GO:0003009)
2.7 10.7 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
2.3 49.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
1.8 7.2 GO:0090113 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
1.8 14.1 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
1.7 5.2 GO:1903373 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
1.7 25.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
1.6 7.9 GO:0015743 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
1.5 4.6 GO:0042421 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
1.5 6.0 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
1.5 16.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
1.4 12.2 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
1.1 19.1 GO:0034629 cellular protein complex localization(GO:0034629)
1.1 12.6 GO:0007525 somatic muscle development(GO:0007525)
0.9 12.1 GO:0090303 positive regulation of wound healing(GO:0090303)
0.8 1.6 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.7 2.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.7 23.7 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.7 2.9 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.7 16.9 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.6 11.5 GO:0014823 response to activity(GO:0014823)
0.6 12.0 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.6 10.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.6 18.2 GO:0050821 protein stabilization(GO:0050821)
0.5 2.0 GO:0003322 pancreatic A cell development(GO:0003322)
0.4 16.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.4 19.9 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.4 2.8 GO:0021570 rhombomere 4 development(GO:0021570) rhombomere 4 morphogenesis(GO:0021661)
0.4 3.8 GO:0098900 regulation of action potential(GO:0098900)
0.4 4.5 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.4 3.6 GO:0006108 malate metabolic process(GO:0006108)
0.4 23.9 GO:0010842 retina layer formation(GO:0010842)
0.3 2.4 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.3 2.1 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.3 11.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.3 4.6 GO:0035108 limb morphogenesis(GO:0035108)
0.3 163.1 GO:0061061 muscle structure development(GO:0061061)
0.3 1.0 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.3 8.3 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.3 2.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.3 1.1 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.2 23.1 GO:0006936 muscle contraction(GO:0006936)
0.2 6.2 GO:0006446 regulation of translational initiation(GO:0006446)
0.2 29.4 GO:0006821 chloride transport(GO:0006821)
0.2 7.7 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.2 4.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2 3.3 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.2 3.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 11.2 GO:0008217 regulation of blood pressure(GO:0008217)
0.1 1.2 GO:1902868 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.1 2.5 GO:0015671 oxygen transport(GO:0015671)
0.1 4.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 4.3 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 1.8 GO:0060030 dorsal convergence(GO:0060030)
0.1 7.7 GO:0071559 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.1 2.3 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 6.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 10.8 GO:0021782 glial cell development(GO:0021782)
0.1 0.4 GO:0006691 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1 7.3 GO:0008213 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.1 1.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 53.4 GO:0016567 protein ubiquitination(GO:0016567)
0.1 1.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 2.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 1.4 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 3.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 3.3 GO:0030336 negative regulation of cell migration(GO:0030336)
0.1 1.4 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 1.5 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 4.1 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 3.4 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 2.1 GO:0048599 oocyte development(GO:0048599)
0.0 4.6 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 2.8 GO:1902284 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0 0.3 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.9 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.6 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.0 4.0 GO:0051260 protein homooligomerization(GO:0051260)
0.0 2.1 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 5.9 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0 3.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 7.1 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.7 GO:0045727 positive regulation of translation(GO:0045727)
0.0 1.9 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.9 GO:0035107 appendage morphogenesis(GO:0035107)
0.0 1.6 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 0.2 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 96.8 GO:0031430 M band(GO:0031430)
3.1 134.0 GO:0005861 troponin complex(GO:0005861)
2.7 127.4 GO:0031941 filamentous actin(GO:0031941)
2.6 39.3 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
2.1 24.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
2.0 19.9 GO:0031672 A band(GO:0031672)
1.7 5.2 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.9 35.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.8 4.2 GO:0034657 GID complex(GO:0034657)
0.7 4.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.7 27.3 GO:0016605 PML body(GO:0016605)
0.6 19.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.5 12.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.4 10.7 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.4 29.0 GO:0034707 chloride channel complex(GO:0034707)
0.3 2.1 GO:0043083 synaptic cleft(GO:0043083)
0.3 3.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 2.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 1.7 GO:0071818 BAT3 complex(GO:0071818)
0.2 3.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 4.9 GO:0043195 terminal bouton(GO:0043195)
0.2 17.5 GO:0070469 respiratory chain(GO:0070469)
0.2 2.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 4.6 GO:0030667 secretory granule membrane(GO:0030667)
0.2 9.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 14.6 GO:0005882 intermediate filament(GO:0005882)
0.1 2.5 GO:0032420 stereocilium(GO:0032420)
0.1 19.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 7.4 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 2.2 GO:0000795 synaptonemal complex(GO:0000795)
0.1 1.6 GO:0005801 cis-Golgi network(GO:0005801)
0.1 9.0 GO:0000786 nucleosome(GO:0000786)
0.1 3.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 60.8 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.1 4.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 5.5 GO:0005581 collagen trimer(GO:0005581)
0.1 22.7 GO:0031966 mitochondrial membrane(GO:0031966)
0.1 1.1 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 1.3 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.0 1.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0071565 nBAF complex(GO:0071565)
0.0 1.3 GO:0016342 catenin complex(GO:0016342)
0.0 2.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 8.5 GO:0045202 synapse(GO:0045202)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.9 GO:0008305 integrin complex(GO:0008305)
0.0 8.7 GO:0005739 mitochondrion(GO:0005739)
0.0 9.7 GO:0030054 cell junction(GO:0030054)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 76.7 GO:0005634 nucleus(GO:0005634)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.2 24.6 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
6.8 27.3 GO:0005521 lamin binding(GO:0005521)
6.4 127.4 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
4.7 52.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
4.6 18.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
3.1 40.3 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
3.0 45.4 GO:0051879 Hsp90 protein binding(GO:0051879)
2.8 8.3 GO:0003994 aconitate hydratase activity(GO:0003994)
2.5 54.0 GO:0005523 tropomyosin binding(GO:0005523)
1.8 18.0 GO:0016936 galactoside binding(GO:0016936)
1.6 7.9 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
1.5 4.6 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
1.5 6.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
1.5 16.2 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
1.4 11.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.3 10.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
1.3 7.8 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.1 11.5 GO:0005522 profilin binding(GO:0005522)
1.1 12.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
1.1 5.3 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
1.0 7.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.9 26.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.9 16.6 GO:0002039 p53 binding(GO:0002039)
0.9 28.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.9 3.6 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.9 24.9 GO:0016208 AMP binding(GO:0016208)
0.9 2.6 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.8 17.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.8 7.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.8 52.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.7 35.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.7 34.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.7 3.5 GO:0050780 mu-type opioid receptor binding(GO:0031852) dopamine receptor binding(GO:0050780) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.7 6.2 GO:0008494 translation activator activity(GO:0008494)
0.7 4.8 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.7 10.4 GO:0031386 protein tag(GO:0031386)
0.6 7.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.5 42.7 GO:0019902 phosphatase binding(GO:0019902)
0.5 1.4 GO:0030882 lipid antigen binding(GO:0030882)
0.4 13.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 9.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 2.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 21.8 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.3 29.4 GO:0005254 chloride channel activity(GO:0005254)
0.3 2.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.3 4.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 229.4 GO:0005509 calcium ion binding(GO:0005509)
0.2 4.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.2 3.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 3.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.2 2.5 GO:0031720 haptoglobin binding(GO:0031720)
0.2 3.8 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.2 3.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 3.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.2 21.5 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.2 4.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 4.0 GO:0030165 PDZ domain binding(GO:0030165)
0.1 6.4 GO:0008276 protein methyltransferase activity(GO:0008276)
0.1 1.7 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.6 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 4.3 GO:0031072 heat shock protein binding(GO:0031072)
0.1 10.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.6 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 23.5 GO:0051015 actin filament binding(GO:0051015)
0.1 7.4 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.1 10.5 GO:0005179 hormone activity(GO:0005179)
0.1 3.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 3.4 GO:0071949 FAD binding(GO:0071949)
0.1 2.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 4.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.3 GO:1990939 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) ATP-dependent microtubule motor activity(GO:1990939)
0.1 18.9 GO:0008017 microtubule binding(GO:0008017)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.7 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 5.8 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 2.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.0 10.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 2.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.3 GO:0019838 growth factor binding(GO:0019838)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 47.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.6 22.4 NABA COLLAGENS Genes encoding collagen proteins
0.3 7.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.3 15.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.3 11.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.3 6.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 16.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 4.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 8.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 3.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 1.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 1.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.0 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 2.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 2.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 47.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
1.1 8.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.0 19.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
1.0 28.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
1.0 11.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.9 18.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.7 10.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.5 22.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.4 4.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.4 6.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.4 8.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.3 3.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.3 2.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.3 3.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 3.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 6.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 3.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)