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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for mnx1+mnx2a+mnx2b

Z-value: 0.59

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Transcription factors associated with mnx1+mnx2a+mnx2b

Gene Symbol Gene ID Gene Info
mnx2b
ENSDARG00000030350 motor neuron and pancreas homeobox 2b
mnx1
ENSDARG00000035984 motor neuron and pancreas homeobox 1
mnx2a
ENSDARG00000042106 motor neuron and pancreas homeobox 2a
mnx1
ENSDARG00000109419 motor neuron and pancreas homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mnx1dr11_v1_chr7_+_40638210_40638210-0.122.7e-01Click!
mnx2adr11_v1_chr9_+_7724152_7724152-0.122.7e-01Click!
mnx2bdr11_v1_chr1_-_5455498_5455502-0.112.7e-01Click!

Activity profile of mnx1+mnx2a+mnx2b motif

Sorted Z-values of mnx1+mnx2a+mnx2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_21867307 5.45 ENSDART00000126629
cbln17
cerebellin 17
chr13_-_36034582 4.80 ENSDART00000133565
si:dkey-157l19.2
si:dkey-157l19.2
chr20_-_40755614 4.58 ENSDART00000061247
cx32.3
connexin 32.3
chr17_+_43867889 4.06 ENSDART00000132673
ENSDART00000167214
zgc:66313
zgc:66313
chr18_+_15644559 3.02 ENSDART00000061794
nr1h4
nuclear receptor subfamily 1, group H, member 4
chr6_+_45918981 2.88 ENSDART00000149642
h6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr7_-_26306546 2.81 ENSDART00000140817
zgc:77439
zgc:77439
chr22_-_24818066 2.61 ENSDART00000143443
vtg6
vitellogenin 6
chr22_+_19552987 2.52 ENSDART00000105315
hsd11b1la
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr11_-_19775182 2.44 ENSDART00000037894
namptb
nicotinamide phosphoribosyltransferase b
chr16_-_42965192 2.33 ENSDART00000113714
mtx1a
metaxin 1a
chr9_+_38163876 2.31 ENSDART00000137955
clasp1a
cytoplasmic linker associated protein 1a
chr13_-_8692860 2.24 ENSDART00000058107
mcfd2
multiple coagulation factor deficiency 2
chr22_-_36836085 2.22 ENSDART00000131451
cart1
cocaine- and amphetamine-regulated transcript 1
chr4_-_9891874 2.20 ENSDART00000067193
adm2a
adrenomedullin 2a
chr8_-_30979494 2.16 ENSDART00000138959
si:ch211-251j10.3
si:ch211-251j10.3
chr6_-_43283122 2.15 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr18_-_14677936 2.15 ENSDART00000111995
si:dkey-238o13.4
si:dkey-238o13.4
chr25_+_10410620 2.01 ENSDART00000151886
ehf
ets homologous factor
chr10_-_8060573 1.92 ENSDART00000147104
ENSDART00000099030
si:ch211-251f6.6
si:ch211-251f6.6
chr8_+_21229718 1.86 ENSDART00000100222
cry1ba
cryptochrome circadian clock 1ba
chr10_-_24371312 1.85 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr20_-_34028967 1.81 ENSDART00000153408
ENSDART00000033817
scyl3
SCY1-like, kinase-like 3
chr16_+_26777473 1.78 ENSDART00000188870
cdh17
cadherin 17, LI cadherin (liver-intestine)
chr15_+_6109861 1.73 ENSDART00000185154
PCP4 (1 of many)
Purkinje cell protein 4
chr6_-_7776612 1.72 ENSDART00000190269
myh9a
myosin, heavy chain 9a, non-muscle
chr15_+_21262917 1.71 ENSDART00000101000
gkup
glucuronokinase with putative uridyl pyrophosphorylase
chr2_-_33993533 1.68 ENSDART00000140910
ENSDART00000077304
ptch2
patched 2
chr2_-_28671139 1.65 ENSDART00000165272
ENSDART00000164657
dhcr7
7-dehydrocholesterol reductase
chr17_+_28103675 1.63 ENSDART00000188078
zgc:91908
zgc:91908
chr24_-_30862168 1.62 ENSDART00000168540
ptbp2a
polypyrimidine tract binding protein 2a
chr3_-_27647845 1.61 ENSDART00000151625
si:ch211-157c3.4
si:ch211-157c3.4
chr21_-_25722834 1.55 ENSDART00000101208
abhd11
abhydrolase domain containing 11
chr10_+_7593185 1.48 ENSDART00000162617
ENSDART00000162590
ENSDART00000171744
ppp2cb
protein phosphatase 2, catalytic subunit, beta isozyme
chr24_-_29963858 1.47 ENSDART00000183442
CR352310.1

chr17_-_40956035 1.46 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr17_-_32863250 1.44 ENSDART00000167292
prox1a
prospero homeobox 1a
chr3_+_32365811 1.44 ENSDART00000155967
ap2a1
adaptor-related protein complex 2, alpha 1 subunit
chr7_+_69019851 1.41 ENSDART00000162891
CABZ01057488.1

chr1_+_44173245 1.39 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
ctnnd1
catenin (cadherin-associated protein), delta 1
chr18_+_8320165 1.39 ENSDART00000092053
chkb
choline kinase beta
chr4_+_16885854 1.38 ENSDART00000017726
etnk1
ethanolamine kinase 1
chr2_+_41526904 1.33 ENSDART00000127520
acvr1l
activin A receptor, type 1 like
chr9_+_34641237 1.32 ENSDART00000133996
shox
short stature homeobox
chr16_+_39159752 1.32 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr2_-_38363017 1.32 ENSDART00000088026
prmt5
protein arginine methyltransferase 5
chr9_-_20372977 1.30 ENSDART00000113418
igsf3
immunoglobulin superfamily, member 3
chr8_+_39998467 1.28 ENSDART00000073782
ENSDART00000134452
ggt5a
gamma-glutamyltransferase 5a
chr16_+_42471455 1.27 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr12_+_30367371 1.24 ENSDART00000153364
ccdc186
si:ch211-225b10.4
chr22_-_20166660 1.23 ENSDART00000085913
ENSDART00000188241
btbd2a
BTB (POZ) domain containing 2a
chr13_+_13945218 1.23 ENSDART00000089501
ENSDART00000142997
eif2ak3
eukaryotic translation initiation factor 2-alpha kinase 3
chr12_-_35830625 1.23 ENSDART00000180028
CU459056.1

chr20_-_37813863 1.18 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr11_-_37691449 1.17 ENSDART00000185340
zgc:158258
zgc:158258
chr18_-_2433011 1.16 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr14_+_35405518 1.16 ENSDART00000171565
zbtb3
zinc finger and BTB domain containing 3
chr14_-_22113600 1.13 ENSDART00000113752
si:dkey-6i22.5
si:dkey-6i22.5
chr14_+_16151368 1.13 ENSDART00000160973
polr1a
polymerase (RNA) I polypeptide A
chr20_-_19511700 1.08 ENSDART00000040191
snx17
sorting nexin 17
chr2_-_40135942 1.08 ENSDART00000176951
ENSDART00000098632
ENSDART00000148563
ENSDART00000149895
epha4a
eph receptor A4a
chr5_+_37032038 1.07 ENSDART00000045036
nfkbib
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr10_+_29850330 1.05 ENSDART00000168898
hspa8
heat shock protein 8
chr3_+_32832538 1.05 ENSDART00000139410
cd2bp2
CD2 (cytoplasmic tail) binding protein 2
chr13_-_31017960 1.04 ENSDART00000145287
wdfy4
WDFY family member 4
chr7_-_31321027 1.04 ENSDART00000186878
CR356242.1

chr16_-_17586883 1.03 ENSDART00000017142
m6pr
mannose-6-phosphate receptor (cation dependent)
chr22_-_10440688 1.03 ENSDART00000111962
nol8
nucleolar protein 8
chr1_+_10318089 1.01 ENSDART00000029774
pip4p1b
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr3_-_16719244 1.00 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr17_+_16046314 0.99 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr1_-_50859053 0.98 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr17_-_21162821 0.97 ENSDART00000157283
abhd12
abhydrolase domain containing 12
chr8_-_24252933 0.97 ENSDART00000057624
zgc:110353
zgc:110353
chr21_-_7035599 0.96 ENSDART00000139777
si:ch211-93g21.1
si:ch211-93g21.1
chr14_+_23717165 0.95 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr15_-_16177603 0.94 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr19_+_30884706 0.94 ENSDART00000052126
yars
tyrosyl-tRNA synthetase
chr16_+_33902006 0.93 ENSDART00000161807
ENSDART00000159474
gnl2
guanine nucleotide binding protein-like 2 (nucleolar)
chr23_+_28809002 0.93 ENSDART00000134121
ENSDART00000183661
pex14
peroxisomal biogenesis factor 14
chr20_+_27712714 0.92 ENSDART00000008306
zbtb1
zinc finger and BTB domain containing 1
chr1_+_52392511 0.90 ENSDART00000144025
si:ch211-217k17.8
si:ch211-217k17.8
chr17_+_14965570 0.89 ENSDART00000066604
gpr137c
G protein-coupled receptor 137c
chr3_+_45368973 0.86 ENSDART00000187282
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr22_-_10397600 0.86 ENSDART00000181964
ENSDART00000142886
nisch
nischarin
chr14_+_35428152 0.86 ENSDART00000172597
sytl4
synaptotagmin-like 4
chr3_-_26806032 0.86 ENSDART00000143710
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr5_+_66433287 0.86 ENSDART00000170757
kntc1
kinetochore associated 1
chr17_+_16090436 0.85 ENSDART00000136059
ENSDART00000138734
znf395a
zinc finger protein 395a
chr22_+_10440991 0.82 ENSDART00000064805
cenpp
centromere protein P
chr6_+_3280939 0.82 ENSDART00000151359
kdm4aa
lysine (K)-specific demethylase 4A, genome duplicate a
chr12_+_30367079 0.82 ENSDART00000190112
ccdc186
si:ch211-225b10.4
chr16_+_23087326 0.82 ENSDART00000167518
ENSDART00000161087
efna3b
ephrin-A3b
chr8_-_25034411 0.81 ENSDART00000135973
nfyal
nuclear transcription factor Y, alpha, like
chr15_+_25528290 0.81 ENSDART00000123143
npat
nuclear protein, ataxia-telangiectasia locus
chr14_+_16151636 0.80 ENSDART00000159352
polr1a
polymerase (RNA) I polypeptide A
chr3_-_38783951 0.78 ENSDART00000155518
znf281a
zinc finger protein 281a
chr24_-_35561672 0.78 ENSDART00000058564
mcm4
minichromosome maintenance complex component 4
chr10_-_8046764 0.77 ENSDART00000099031
zgc:136254
zgc:136254
chr13_-_25819825 0.77 ENSDART00000077612
rel
v-rel avian reticuloendotheliosis viral oncogene homolog
chr9_-_24244383 0.76 ENSDART00000182407
cavin2a
caveolae associated protein 2a
chr7_+_17229980 0.75 ENSDART00000184910
slc6a5
solute carrier family 6 (neurotransmitter transporter), member 5
chr10_+_33744098 0.74 ENSDART00000147775
rxfp2a
relaxin/insulin-like family peptide receptor 2a
chr16_-_17162843 0.73 ENSDART00000089386
iffo1b
intermediate filament family orphan 1b
chr7_-_71389375 0.73 ENSDART00000128928
CABZ01074298.1

chr19_+_42432625 0.72 ENSDART00000076938
pogza
pogo transposable element derived with ZNF domain a
chr11_-_44801968 0.71 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr19_-_30524952 0.71 ENSDART00000103506
hpcal4
hippocalcin like 4
chr1_+_45056371 0.71 ENSDART00000073689
ENSDART00000167309
btr01
bloodthirsty-related gene family, member 1
chr5_-_25733745 0.71 ENSDART00000051566
zgc:101016
zgc:101016
chr22_-_7129631 0.70 ENSDART00000171359
asic1b
acid-sensing (proton-gated) ion channel 1b
chr11_-_39118882 0.69 ENSDART00000113185
ENSDART00000156526
ap5b1
adaptor-related protein complex 5, beta 1 subunit
chr1_+_12766351 0.66 ENSDART00000165785
pcdh10a
protocadherin 10a
chr19_-_19379084 0.65 ENSDART00000165206
smarcc1b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b
chr1_-_45616470 0.65 ENSDART00000150165
atf7ip
activating transcription factor 7 interacting protein
chr24_-_40860603 0.64 ENSDART00000188032
CU633479.7

chr5_+_25733774 0.63 ENSDART00000137088
ENSDART00000098467
abhd17b
abhydrolase domain containing 17B
chr10_+_42521943 0.63 ENSDART00000010420
ENSDART00000075303
actr1
ARP1 actin related protein 1, centractin
chr3_+_32553714 0.63 ENSDART00000165638
pax10
paired box 10
chr4_-_15103646 0.63 ENSDART00000138183
ENSDART00000181044
nrf1
nuclear respiratory factor 1
chr2_-_38206034 0.62 ENSDART00000144518
ENSDART00000137395
acin1a
apoptotic chromatin condensation inducer 1a
chr16_+_35916371 0.61 ENSDART00000167208
sh3d21
SH3 domain containing 21
chr25_-_27722614 0.61 ENSDART00000190154
zgc:153935
zgc:153935
chr19_+_40069524 0.60 ENSDART00000151365
ENSDART00000140926
zmym4
zinc finger, MYM-type 4
chr23_-_40766518 0.60 ENSDART00000127420
si:dkeyp-27c8.2
si:dkeyp-27c8.2
chr15_+_857148 0.59 ENSDART00000156949
si:dkey-7i4.13
si:dkey-7i4.13
chr17_+_31221761 0.58 ENSDART00000155580
ccdc32
coiled-coil domain containing 32
chr8_-_39822917 0.57 ENSDART00000067843
zgc:162025
zgc:162025
chr20_-_48485354 0.57 ENSDART00000124040
ENSDART00000148437
insm1a
insulinoma-associated 1a
chr15_-_26931541 0.57 ENSDART00000027563
ccdc9
coiled-coil domain containing 9
chr21_+_5580948 0.56 ENSDART00000160373
ly6m7
lymphocyte antigen 6 family member M7
chr8_+_2487250 0.56 ENSDART00000081325
dynll1
dynein, light chain, LC8-type 1
chr17_+_49500820 0.55 ENSDART00000170306
AREL1
apoptosis resistant E3 ubiquitin protein ligase 1
chr8_+_23355484 0.53 ENSDART00000085361
ENSDART00000125729
dnmt3ba
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr18_+_19456648 0.52 ENSDART00000079695
zwilch
zwilch kinetochore protein
chr10_+_11282883 0.52 ENSDART00000135355
si:ch211-126i22.5
si:ch211-126i22.5
chr7_+_25059845 0.50 ENSDART00000077215
ppp2r5b
protein phosphatase 2, regulatory subunit B', beta
chr3_+_13624815 0.49 ENSDART00000161451
pglyrp6
peptidoglycan recognition protein 6
chr10_-_8053385 0.49 ENSDART00000142714
si:ch211-251f6.7
si:ch211-251f6.7
chr17_-_44249720 0.48 ENSDART00000156648
otx2b
orthodenticle homeobox 2b
chr19_-_5103141 0.48 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr5_+_66353750 0.48 ENSDART00000143410
si:ch211-261c8.5
si:ch211-261c8.5
chr1_-_44701313 0.48 ENSDART00000193926
si:dkey-28b4.8
si:dkey-28b4.8
chr12_+_24342303 0.47 ENSDART00000111239
nrxn1a
neurexin 1a
chr20_-_45812144 0.46 ENSDART00000147897
ENSDART00000147637
fermt1
fermitin family member 1
chr14_+_33329420 0.45 ENSDART00000171090
ENSDART00000164062
sowahd
sosondowah ankyrin repeat domain family d
chr19_-_44065581 0.43 ENSDART00000006338
mterf3
mitochondrial transcription termination factor 3
chr10_-_25217347 0.42 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr10_+_43039947 0.42 ENSDART00000193434
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr12_+_22580579 0.42 ENSDART00000171725
ENSDART00000192290
capgb
capping protein (actin filament), gelsolin-like b
chr7_+_19552381 0.40 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr2_-_32384683 0.40 ENSDART00000182942
ENSDART00000141757
ubtfl
upstream binding transcription factor, like
chr13_-_4018888 0.40 ENSDART00000058238
tjap1
tight junction associated protein 1 (peripheral)
chr5_+_66353589 0.40 ENSDART00000138246
si:ch211-261c8.5
si:ch211-261c8.5
chr20_+_31076488 0.40 ENSDART00000136255
ENSDART00000008840
otofa
otoferlin a
chr14_+_49135264 0.39 ENSDART00000084119
si:ch1073-44g3.1
si:ch1073-44g3.1
chr15_+_5360407 0.39 ENSDART00000110420
or112-1
odorant receptor, family A, subfamily 112, member 1
chr17_+_23298928 0.38 ENSDART00000153652
zgc:165461
zgc:165461
chr13_-_27354003 0.37 ENSDART00000101479
ENSDART00000044652
ddx43
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr16_-_42056137 0.36 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr18_-_33979693 0.36 ENSDART00000021215
si:ch211-203b20.7
si:ch211-203b20.7
chr23_+_30967686 0.36 ENSDART00000144485
si:ch211-197l9.2
si:ch211-197l9.2
chr1_-_10647484 0.35 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
si:dkey-31e10.1
chr8_-_50888806 0.34 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr11_-_6452444 0.34 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
larp6b
La ribonucleoprotein domain family, member 6b
chr25_+_35553542 0.34 ENSDART00000113723
spi1a
Spi-1 proto-oncogene a
chr6_-_39649504 0.32 ENSDART00000179960
ENSDART00000190951
larp4ab
La ribonucleoprotein domain family, member 4Ab
chr8_+_2487883 0.31 ENSDART00000101841
dynll1
dynein, light chain, LC8-type 1
chr1_+_50613868 0.31 ENSDART00000111114
HERC5
si:ch73-190m4.1
chr24_+_5912635 0.31 ENSDART00000153736
pimr63
Pim proto-oncogene, serine/threonine kinase, related 63
chr5_+_66063807 0.31 ENSDART00000122405
jak2b
Janus kinase 2b
chr24_-_6078222 0.31 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr8_+_45334255 0.30 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr11_+_24820542 0.30 ENSDART00000135443
kdm5ba
lysine (K)-specific demethylase 5Ba
chr20_-_7128612 0.30 ENSDART00000146755
ENSDART00000036871
si:ch211-121a2.4
si:ch211-121a2.4
chr3_+_46635527 0.28 ENSDART00000153971
si:dkey-248g21.1
si:dkey-248g21.1
chr5_-_48664522 0.28 ENSDART00000083229
mblac2
metallo-beta-lactamase domain containing 2
chr23_-_36418059 0.27 ENSDART00000135232
znf740b
zinc finger protein 740b
chr20_-_23426339 0.27 ENSDART00000004625
zar1
zygote arrest 1
chr9_+_50001746 0.26 ENSDART00000058892
slc38a11
solute carrier family 38, member 11
chr3_-_32873641 0.25 ENSDART00000075277
zgc:113090
zgc:113090
chr10_-_28028998 0.25 ENSDART00000023545
ENSDART00000143487
ints2
integrator complex subunit 2
chr19_+_22062202 0.25 ENSDART00000100181
sall3b
spalt-like transcription factor 3b
chr1_-_22512063 0.24 ENSDART00000031546
ENSDART00000190987
chrna6
cholinergic receptor, nicotinic, alpha 6
chr4_-_16334362 0.23 ENSDART00000101461
epyc
epiphycan
chr1_+_11977426 0.22 ENSDART00000103399
tspan5b
tetraspanin 5b
chr9_-_14273652 0.21 ENSDART00000135458
abcb6b
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr1_+_33969015 0.20 ENSDART00000042984
ENSDART00000146530
epha6
eph receptor A6
chr8_-_34052019 0.19 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pbx3b
pre-B-cell leukemia homeobox 3b
chr23_+_45200481 0.19 ENSDART00000004357
ENSDART00000111126
ENSDART00000193560
ENSDART00000190476
psip1b
PC4 and SFRS1 interacting protein 1b
chr16_-_29387215 0.19 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr2_+_20332044 0.19 ENSDART00000112131
plppr4a
phospholipid phosphatase related 4a
chr20_-_35040041 0.19 ENSDART00000131919
kif26bb
kinesin family member 26Bb
chr6_-_11780070 0.18 ENSDART00000151195
march7
membrane-associated ring finger (C3HC4) 7
chr3_+_33341640 0.18 ENSDART00000186352
pyya
peptide YYa
chr13_+_38430466 0.17 ENSDART00000132691
adgrb3
adhesion G protein-coupled receptor B3
chr4_+_12612145 0.17 ENSDART00000181201
lmo3
LIM domain only 3
chr1_-_32111882 0.17 ENSDART00000112639
ENSDART00000101958
pnpla4
patatin-like phospholipase domain containing 4
chr5_+_20147830 0.17 ENSDART00000098727
svopa
SV2 related protein a
chr11_+_18157260 0.17 ENSDART00000144659
zgc:173545
zgc:173545

Network of associatons between targets according to the STRING database.

First level regulatory network of mnx1+mnx2a+mnx2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0072103 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.3 1.3 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.3 1.3 GO:0060074 synapse maturation(GO:0060074)
0.3 1.3 GO:0034969 histone arginine methylation(GO:0034969)
0.3 2.2 GO:0008343 adult feeding behavior(GO:0008343)
0.3 1.3 GO:0006691 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.3 1.0 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2 2.9 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.2 0.9 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.2 3.0 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.2 0.9 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.2 0.6 GO:0070417 cellular response to cold(GO:0070417)
0.2 1.0 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.2 1.7 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.2 1.1 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.2 0.5 GO:0016045 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.2 1.1 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.1 1.9 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.9 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.8 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.5 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.8 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 0.4 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.6 GO:0097065 anterior head development(GO:0097065)
0.1 0.7 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.7 GO:0043092 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.1 0.9 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 0.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.6 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 0.9 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 1.6 GO:0042446 hormone biosynthetic process(GO:0042446)
0.1 1.4 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.1 2.6 GO:0032355 response to estradiol(GO:0032355)
0.1 0.5 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.1 0.7 GO:0007190 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.1 2.3 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.6 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 1.1 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.6 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.8 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.7 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.7 GO:0097324 melanocyte migration(GO:0097324)
0.0 1.4 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0033512 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.8 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 3.9 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.4 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.8 GO:0008345 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 1.9 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.8 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 2.8 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 1.3 GO:0030282 bone mineralization(GO:0030282)
0.0 1.0 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 2.1 GO:0099518 vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.2 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 2.0 GO:0050673 epithelial cell proliferation(GO:0050673)
0.0 1.9 GO:0001666 response to hypoxia(GO:0001666)
0.0 0.4 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.5 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.3 GO:0002761 regulation of myeloid leukocyte differentiation(GO:0002761)
0.0 1.0 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 1.8 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.3 0.9 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.3 2.3 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.3 1.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.3 1.3 GO:0070724 BMP receptor complex(GO:0070724)
0.2 1.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 1.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 3.9 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 1.0 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 3.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.7 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 3.2 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.8 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 2.1 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.9 GO:0016342 catenin complex(GO:0016342)
0.0 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 2.2 GO:0005769 early endosome(GO:0005769)
0.0 0.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 1.3 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.5 3.0 GO:0032052 bile acid binding(GO:0032052)
0.4 1.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.4 1.7 GO:0097108 hedgehog family protein binding(GO:0097108)
0.4 2.6 GO:0045735 nutrient reservoir activity(GO:0045735)
0.3 2.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 1.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.3 1.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.3 2.3 GO:0043515 kinetochore binding(GO:0043515)
0.2 0.9 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.2 1.0 GO:0050699 WW domain binding(GO:0050699)
0.2 0.5 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 1.3 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 0.4 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.7 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 1.0 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.9 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.5 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 1.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 3.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.0 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 2.5 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.1 2.1 GO:0031267 small GTPase binding(GO:0031267)
0.1 1.0 GO:0005537 mannose binding(GO:0005537)
0.1 1.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.6 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 1.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.3 GO:0019894 kinesin binding(GO:0019894)
0.1 0.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 2.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.9 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 1.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 1.7 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.1 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.3 GO:0045296 cadherin binding(GO:0045296)
0.0 1.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 1.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.4 PID ARF 3PATHWAY Arf1 pathway
0.1 0.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.1 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 2.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 1.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.0 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.2 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 1.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 2.2 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 1.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.8 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters