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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for msc

Z-value: 0.83

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Transcription factors associated with msc

Gene Symbol Gene ID Gene Info
msc
ENSDARG00000110016 musculin (activated B-cell factor-1)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mscdr11_v1_chr24_+_13735616_13735616-0.381.4e-04Click!

Activity profile of msc motif

Sorted Z-values of msc motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_18057851 6.61 ENSDART00000173075
ENSDART00000173230
ENSDART00000173135
ENSDART00000173431
ENSDART00000173068
ENSDART00000172987
zgc:92287
zgc:92287
chr21_+_27382893 6.43 ENSDART00000005682
actn3a
actinin alpha 3a
chr23_-_18057553 6.43 ENSDART00000173102
ENSDART00000058742
zgc:92287
zgc:92287
chr20_-_27325258 6.35 ENSDART00000152917
asb2a.1
ankyrin repeat and SOCS box containing 2a, tandem duplicate 1
chr13_+_24834199 5.90 ENSDART00000101274
zgc:153981
zgc:153981
chr21_-_43952958 5.36 ENSDART00000039571
camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr5_-_51819027 5.21 ENSDART00000164267
homer1b
homer scaffolding protein 1b
chr6_+_13742899 5.02 ENSDART00000104722
cdk5r2a
cyclin-dependent kinase 5, regulatory subunit 2a (p39)
chr1_-_25911292 4.90 ENSDART00000145012
usp53b
ubiquitin specific peptidase 53b
chr15_-_15357178 4.72 ENSDART00000106120
ywhag2
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2
chr5_-_38451082 4.55 ENSDART00000136428
chrne
cholinergic receptor, nicotinic, epsilon
chr6_+_23887314 4.39 ENSDART00000163188
znf648
zinc finger protein 648
chr1_+_25801648 4.38 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr9_+_40939336 4.34 ENSDART00000100386
mstnb
myostatin b
chr2_-_44255537 4.22 ENSDART00000011188
ENSDART00000093298
atp1a2a
ATPase Na+/K+ transporting subunit alpha 2
chr5_-_31904562 4.07 ENSDART00000140640
coro1cb
coronin, actin binding protein, 1Cb
chr23_-_18057270 3.96 ENSDART00000173385
zgc:92287
zgc:92287
chr7_+_31879649 3.90 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr11_-_5865744 3.83 ENSDART00000104360
gamt
guanidinoacetate N-methyltransferase
chr7_+_26224211 3.81 ENSDART00000173999
vgf
VGF nerve growth factor inducible
chr14_-_32255126 3.74 ENSDART00000017259
fgf13a
fibroblast growth factor 13a
chr7_+_6969909 3.69 ENSDART00000189886
actn3b
actinin alpha 3b
chr7_+_31879986 3.67 ENSDART00000138491
mybpc3
myosin binding protein C, cardiac
chr13_-_41155472 3.60 ENSDART00000160588
si:dkeyp-86d6.2
si:dkeyp-86d6.2
chr11_-_1291012 3.56 ENSDART00000158390
atp2b2
ATPase plasma membrane Ca2+ transporting 2
chr13_-_31452516 3.45 ENSDART00000193268
rtn1a
reticulon 1a
chr2_-_42128714 3.34 ENSDART00000047055
trim55a
tripartite motif containing 55a
chr1_+_33401774 3.29 ENSDART00000149786
ENSDART00000110026
ENSDART00000148946
dhrsx
dehydrogenase/reductase (SDR family) X-linked
chr10_+_15777064 3.26 ENSDART00000114483
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr3_-_28075756 3.20 ENSDART00000122037
rbfox1
RNA binding fox-1 homolog 1
chr10_+_15777258 3.19 ENSDART00000140511
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr7_+_7048245 3.19 ENSDART00000001649
actn3b
actinin alpha 3b
chr20_+_35382482 3.19 ENSDART00000135284
vsnl1a
visinin-like 1a
chr5_+_3501859 3.15 ENSDART00000080486
ywhag1
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr5_+_42097608 3.08 ENSDART00000014404
p2rx5
purinergic receptor P2X, ligand-gated ion channel, 5
chr7_-_23745984 3.08 ENSDART00000048050
ITGB1BP2
zgc:92429
chr15_+_40188076 3.02 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr19_-_9711472 2.93 ENSDART00000016197
ENSDART00000175075
slc2a3a
solute carrier family 2 (facilitated glucose transporter), member 3a
chr21_+_11468642 2.92 ENSDART00000041869
grin1a
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr6_+_39222598 2.90 ENSDART00000154991
b4galnt1b
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr9_-_49531762 2.85 ENSDART00000121875
xirp2b
xin actin binding repeat containing 2b
chr2_-_32551178 2.85 ENSDART00000145603
smarcd3a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr19_-_10425140 2.76 ENSDART00000145319
si:ch211-171h4.3
si:ch211-171h4.3
chr7_+_19552381 2.70 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr1_-_54997746 2.60 ENSDART00000152666
slc25a23a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23a
chr14_+_21783229 2.59 ENSDART00000170784
ankrd13d
ankyrin repeat domain 13 family, member D
chr23_+_35714574 2.55 ENSDART00000164616
tuba1c
tubulin, alpha 1c
chr6_+_40587551 2.54 ENSDART00000155554
frs3
fibroblast growth factor receptor substrate 3
chr13_-_40499296 2.53 ENSDART00000158338
CNNM1
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr15_+_33989181 2.51 ENSDART00000169487
vwde
von Willebrand factor D and EGF domains
chr3_-_36115339 2.47 ENSDART00000187406
ENSDART00000123505
ENSDART00000151775
rab11fip4a
RAB11 family interacting protein 4 (class II) a
chr24_+_26276805 2.45 ENSDART00000089749
adipoqa
adiponectin, C1Q and collagen domain containing, a
chr21_+_11468934 2.45 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
grin1a
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr22_+_16308450 2.44 ENSDART00000105678
lrrc39
leucine rich repeat containing 39
chr21_-_16632808 2.43 ENSDART00000172645
unc5da
unc-5 netrin receptor Da
chr18_-_5781922 2.41 ENSDART00000128722
RGS9BP
si:ch73-167i17.6
chr23_-_8373676 2.38 ENSDART00000105135
ENSDART00000158531
oprl1
opiate receptor-like 1
chr11_-_17713987 2.37 ENSDART00000090401
fam19a4b
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4b
chr14_+_5936996 2.37 ENSDART00000097144
ENSDART00000126777
kctd8
potassium channel tetramerization domain containing 8
chr24_+_38155830 2.35 ENSDART00000152019
si:ch211-234p6.5
si:ch211-234p6.5
chr15_-_9421481 2.33 ENSDART00000189045
ENSDART00000177158
sacs
sacsin molecular chaperone
chr9_-_98982 2.31 ENSDART00000147882
lims2
LIM and senescent cell antigen-like domains 2
chr10_+_34315719 2.30 ENSDART00000135303
stard13a
StAR-related lipid transfer (START) domain containing 13a
chr22_+_16308806 2.30 ENSDART00000162685
lrrc39
leucine rich repeat containing 39
chr23_-_32162810 2.25 ENSDART00000155905
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr10_-_34741738 2.24 ENSDART00000163072
dclk1a
doublecortin-like kinase 1a
chr7_+_27277236 2.23 ENSDART00000185161
sox6
SRY (sex determining region Y)-box 6
chr17_-_14836320 2.22 ENSDART00000157051
nid2a
nidogen 2a (osteonidogen)
chr10_-_25217347 2.18 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr6_-_8865217 2.16 ENSDART00000151443
tmeff2b
transmembrane protein with EGF-like and two follistatin-like domains 2b
chr5_-_19400166 2.15 ENSDART00000008994
foxn4
forkhead box N4
chr17_-_14726824 2.11 ENSDART00000162947
si:ch73-305o9.3
si:ch73-305o9.3
chr14_+_21783400 2.11 ENSDART00000164023
ankrd13d
ankyrin repeat domain 13 family, member D
chr7_+_20471315 2.11 ENSDART00000173714
si:dkey-19b23.13
si:dkey-19b23.13
chr6_-_16667886 2.10 ENSDART00000180854
ENSDART00000190116
unc80
unc-80 homolog (C. elegans)
chr13_+_1575276 2.07 ENSDART00000165987
DST
dystonin
chr19_-_10432134 2.06 ENSDART00000081440
il11b
interleukin 11b
chr24_+_20575259 2.03 ENSDART00000010488
klhl40b
kelch-like family member 40b
chr19_+_1184878 2.03 ENSDART00000163539
scrt1a
scratch family zinc finger 1a
chr22_+_465269 2.01 ENSDART00000145767
celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr23_+_29908348 2.01 ENSDART00000186622
ENSDART00000150174
si:ch73-236e11.2
si:ch73-236e11.2
chr24_+_24461558 2.00 ENSDART00000182424
bhlhe22
basic helix-loop-helix family, member e22
chr11_+_14622379 1.98 ENSDART00000112589
efna2b
ephrin-A2b
chr17_-_4245311 1.96 ENSDART00000055379
gdf3
growth differentiation factor 3
chr15_+_9327252 1.94 ENSDART00000144381
sgcg
sarcoglycan, gamma
chr8_-_44004135 1.92 ENSDART00000136269
rimbp2
RIMS binding protein 2
chr20_-_39391833 1.91 ENSDART00000135149
si:dkey-217m5.8
si:dkey-217m5.8
chr19_+_9174166 1.91 ENSDART00000104637
ENSDART00000150968
si:ch211-81a5.8
si:ch211-81a5.8
chr2_+_45696743 1.90 ENSDART00000114225
ENSDART00000169279
CU467828.1

chr9_+_52492639 1.90 ENSDART00000078939
march4
membrane-associated ring finger (C3HC4) 4
chr25_+_36045072 1.89 ENSDART00000126326
rpgrip1l
RPGRIP1-like
chr3_+_29714775 1.89 ENSDART00000041388
cacng2a
calcium channel, voltage-dependent, gamma subunit 2a
chr5_+_57924611 1.88 ENSDART00000050949
btg4
B-cell translocation gene 4
chr15_-_32383529 1.88 ENSDART00000028349
c4
complement component 4
chr19_-_33087246 1.86 ENSDART00000052078
klhl38a
kelch-like family member 38a
chr20_-_42439896 1.85 ENSDART00000061049
vgll2a
vestigial-like family member 2a
chr6_-_10912424 1.85 ENSDART00000036456
cycsb
cytochrome c, somatic b
chr22_-_10470663 1.84 ENSDART00000143352
omd
osteomodulin
chr8_-_43997538 1.81 ENSDART00000186449
rimbp2
RIMS binding protein 2
chr8_-_11229523 1.77 ENSDART00000002164
unc45b
unc-45 myosin chaperone B
chr6_+_27339962 1.71 ENSDART00000193726
klhl30
kelch-like family member 30
chr12_-_28570989 1.63 ENSDART00000008010
pdk2a
pyruvate dehydrogenase kinase, isozyme 2a
chr1_-_17650223 1.60 ENSDART00000043484
si:dkey-256e7.5
si:dkey-256e7.5
chr23_-_30954738 1.60 ENSDART00000188996
osbpl2a
oxysterol binding protein-like 2a
chr14_-_9355177 1.58 ENSDART00000138535
fam46d
family with sequence similarity 46, member D
chr19_-_32888758 1.57 ENSDART00000052080
laptm4b
lysosomal protein transmembrane 4 beta
chr18_-_7948188 1.54 ENSDART00000091805
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr2_-_15040345 1.52 ENSDART00000109657
si:dkey-10f21.4
si:dkey-10f21.4
chr2_-_23768818 1.52 ENSDART00000148685
ENSDART00000191167
xirp1
xin actin binding repeat containing 1
chr1_-_14258409 1.50 ENSDART00000079359
pde5aa
phosphodiesterase 5A, cGMP-specific, a
chr21_-_17482465 1.50 ENSDART00000004548
barhl1b
BarH-like homeobox 1b
chr7_-_35516251 1.49 ENSDART00000045628
irx6a
iroquois homeobox 6a
chr2_-_36933472 1.48 ENSDART00000170405
BX470229.2

chr20_+_27020201 1.48 ENSDART00000126919
ENSDART00000016014
chga
chromogranin A
chr5_-_60159116 1.48 ENSDART00000147675
si:dkey-280e8.1
si:dkey-280e8.1
chr10_-_25069155 1.46 ENSDART00000078226
ENSDART00000181941
mtnr1bb
melatonin receptor 1Bb
chr4_+_12617108 1.46 ENSDART00000134362
ENSDART00000112860
lmo3
LIM domain only 3
chr4_+_12615836 1.46 ENSDART00000003583
lmo3
LIM domain only 3
chr13_+_24287093 1.42 ENSDART00000058628
ccsapb
centriole, cilia and spindle-associated protein b
chr6_+_4872883 1.41 ENSDART00000186730
ENSDART00000092290
ENSDART00000151674
pcdh9
protocadherin 9
chr17_+_6276559 1.41 ENSDART00000131075
dusp23b
dual specificity phosphatase 23b
chr3_+_20156956 1.40 ENSDART00000125281
ngfra
nerve growth factor receptor a (TNFR superfamily, member 16)
chr4_-_20081621 1.40 ENSDART00000024647
dennd6b
DENN/MADD domain containing 6B
chr20_+_18580176 1.40 ENSDART00000185310
si:dkeyp-72h1.1
si:dkeyp-72h1.1
chr1_+_2101541 1.39 ENSDART00000128187
ENSDART00000167050
ENSDART00000182153
ENSDART00000122626
ENSDART00000164488
mbnl2
muscleblind-like splicing regulator 2
chr1_+_20593653 1.38 ENSDART00000132440
si:ch211-142c4.1
si:ch211-142c4.1
chr23_-_27647769 1.38 ENSDART00000059974
wnt10b
wingless-type MMTV integration site family, member 10b
chr5_-_10768258 1.37 ENSDART00000157043
rtn4r
reticulon 4 receptor
chr6_+_46259950 1.34 ENSDART00000032326
zgc:162324
zgc:162324
chr18_+_39028417 1.34 ENSDART00000148428
myo5aa
myosin VAa
chr19_-_19505167 1.33 ENSDART00000160582
creb5a
cAMP responsive element binding protein 5a
chr7_+_27253063 1.32 ENSDART00000191138
sox6
SRY (sex determining region Y)-box 6
chr12_+_33038757 1.32 ENSDART00000153146
rbfox3a
RNA binding fox-1 homolog 3a
chr1_-_29747702 1.31 ENSDART00000133225
ENSDART00000189670
spp2
secreted phosphoprotein 2
chr20_-_39391492 1.30 ENSDART00000184886
si:dkey-217m5.8
si:dkey-217m5.8
chr4_+_12113105 1.29 ENSDART00000182399
tmem178b
transmembrane protein 178B
chr7_+_66634167 1.29 ENSDART00000027616
eif4g2a
eukaryotic translation initiation factor 4, gamma 2a
chr17_+_12075805 1.28 ENSDART00000155329
cnsta
consortin, connexin sorting protein a
chr20_-_18915376 1.27 ENSDART00000063725
xkr6b
XK, Kell blood group complex subunit-related family, member 6b
chr1_-_17587552 1.27 ENSDART00000039917
acsl1a
acyl-CoA synthetase long chain family member 1a
chr16_+_28728347 1.26 ENSDART00000149240
si:dkey-24i24.3
si:dkey-24i24.3
chr20_+_25645459 1.26 ENSDART00000143555
ENSDART00000036350
aasdh
aminoadipate-semialdehyde dehydrogenase
chr11_-_36963988 1.26 ENSDART00000168288
cacna1da
calcium channel, voltage-dependent, L type, alpha 1D subunit, a
chr2_-_17115256 1.26 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr8_-_24965308 1.26 ENSDART00000087293
ENSDART00000146805
kcnc4
potassium voltage-gated channel, Shaw-related subfamily, member 4
chr17_-_21066075 1.25 ENSDART00000078763
ENSDART00000104327
vsx1
visual system homeobox 1 homolog, chx10-like
chr21_-_27123139 1.23 ENSDART00000077478
slc8a4a
solute carrier family 8 (sodium/calcium exchanger), member 4a
chr18_+_19820008 1.22 ENSDART00000079691
ENSDART00000135049
iqch
IQ motif containing H
chr4_-_75175407 1.21 ENSDART00000180125
CABZ01043953.1

chr5_-_22019061 1.21 ENSDART00000113066
amer1
APC membrane recruitment protein 1
chr3_+_17910569 1.21 ENSDART00000080946
ttc25
tetratricopeptide repeat domain 25
chr2_+_10642047 1.20 ENSDART00000091570
fam69aa
family with sequence similarity 69, member Aa
chr2_+_38881165 1.19 ENSDART00000141850
carmil3
capping protein regulator and myosin 1 linker 3
chr2_-_30659222 1.18 ENSDART00000145405
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr15_+_32727848 1.17 ENSDART00000161361
postnb
periostin, osteoblast specific factor b
chr21_-_38618540 1.17 ENSDART00000036600
slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr6_+_28051978 1.16 ENSDART00000143218
si:ch73-194h10.2
si:ch73-194h10.2
chr12_-_10505986 1.16 ENSDART00000152672
zgc:152977
zgc:152977
chr6_-_12722360 1.15 ENSDART00000090174
dock9b
dedicator of cytokinesis 9b
chr4_-_9586713 1.15 ENSDART00000145613
shank3b
SH3 and multiple ankyrin repeat domains 3b
chr22_-_18179214 1.15 ENSDART00000129576
si:ch211-125m10.6
si:ch211-125m10.6
chr10_+_24468922 1.15 ENSDART00000008248
ENSDART00000183510
slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr22_+_24770744 1.15 ENSDART00000142882
si:rp71-23d18.4
si:rp71-23d18.4
chr10_+_35491216 1.15 ENSDART00000109705
phldb2a
pleckstrin homology-like domain, family B, member 2a
chr3_+_36515376 1.14 ENSDART00000161652
si:dkeyp-72e1.9
si:dkeyp-72e1.9
chr9_+_2020667 1.13 ENSDART00000157818
lnpa
limb and neural patterns a
chr15_-_38009344 1.13 ENSDART00000157094
si:dkey-238d18.6
si:dkey-238d18.6
chr20_-_18731268 1.13 ENSDART00000183893
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr22_+_35472653 1.13 ENSDART00000076424
ENSDART00000187204
tctex1d2
Tctex1 domain containing 2
chr24_-_9300160 1.12 ENSDART00000152378
tgif1
TGFB-induced factor homeobox 1
chr23_-_24263474 1.11 ENSDART00000160312
hspb7
heat shock protein family, member 7 (cardiovascular)
chr21_-_32684570 1.10 ENSDART00000162873
adamts2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr14_+_36628131 1.09 ENSDART00000188625
ENSDART00000125345
TENM3
si:dkey-237h12.3
chr8_+_25247245 1.09 ENSDART00000045798
ampd2b
adenosine monophosphate deaminase 2b
chr14_+_7939398 1.08 ENSDART00000189773
cxxc5b
CXXC finger protein 5b
chr2_+_29257942 1.07 ENSDART00000184362
ENSDART00000025562
cdh18a
cadherin 18, type 2a
chr15_-_32383340 1.06 ENSDART00000185632
c4
complement component 4
chr7_+_27059330 1.06 ENSDART00000173919
plekha7b
pleckstrin homology domain containing, family A member 7b
chr12_+_17504559 1.06 ENSDART00000020628
cyth3a
cytohesin 3a
chr8_+_29742237 1.06 ENSDART00000133955
ENSDART00000020621
mapk4
mitogen-activated protein kinase 4
chr8_+_45334255 1.04 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr20_+_46560258 1.04 ENSDART00000122115
si:ch211-153j24.3
si:ch211-153j24.3
chr23_-_7826849 1.03 ENSDART00000157612
myt1b
myelin transcription factor 1b
chr17_-_50020672 1.03 ENSDART00000188942
filip1a
filamin A interacting protein 1a
chr10_+_10738880 1.01 ENSDART00000004181
slc27a4
solute carrier family 27 (fatty acid transporter), member 4
chr16_+_30933044 0.99 ENSDART00000184453
gstk2
glutathione S-transferase kappa 2
chr11_-_11266882 0.99 ENSDART00000020256
lgsn
lengsin, lens protein with glutamine synthetase domain
chr10_+_26871751 0.99 ENSDART00000089205
ehbp1l1b
EH domain binding protein 1-like 1b
chr5_+_34622320 0.95 ENSDART00000141338
enc1
ectodermal-neural cortex 1
chr25_-_35542739 0.95 ENSDART00000097651
si:ch211-87j1.4
si:ch211-87j1.4
chr19_+_44039849 0.95 ENSDART00000086040
lrrc14b
leucine rich repeat containing 14B
chr16_-_13281380 0.95 ENSDART00000103882
grin2db
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr18_+_25003207 0.94 ENSDART00000099476
ENSDART00000132285
fam174b
family with sequence similarity 174, member B
chr3_-_23596532 0.93 ENSDART00000124921
ube2z
ubiquitin-conjugating enzyme E2Z
chr14_+_7939216 0.93 ENSDART00000171657
cxxc5b
CXXC finger protein 5b
chr15_-_8517376 0.93 ENSDART00000186289
npas1
neuronal PAS domain protein 1
chr15_+_37992275 0.91 ENSDART00000154928
si:dkey-238d18.7
si:dkey-238d18.7
chr20_+_23501535 0.91 ENSDART00000177922
ENSDART00000058532
palld
palladin, cytoskeletal associated protein
chr13_-_31164749 0.90 ENSDART00000049180
mapk8a
mitogen-activated protein kinase 8a
chr25_-_36044583 0.90 ENSDART00000073432
rbl2
retinoblastoma-like 2 (p130)

Network of associatons between targets according to the STRING database.

First level regulatory network of msc

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.6 GO:0003210 cardiac atrium formation(GO:0003210)
1.4 4.2 GO:0065001 specification of axis polarity(GO:0065001)
1.3 3.8 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
1.1 4.4 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
1.1 4.3 GO:1901862 negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.7 5.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.7 2.0 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.5 1.5 GO:0002792 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.4 1.3 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.4 1.3 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.4 7.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.4 2.0 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.4 2.7 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.4 1.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.4 4.9 GO:0010996 response to auditory stimulus(GO:0010996)
0.4 2.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.4 6.4 GO:0051764 actin crosslink formation(GO:0051764)
0.4 3.6 GO:0060612 adipose tissue development(GO:0060612)
0.4 1.4 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.3 2.8 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.3 2.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.3 2.0 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.3 3.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.3 0.8 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.3 1.0 GO:0003322 pancreatic A cell development(GO:0003322)
0.3 3.1 GO:0033198 response to ATP(GO:0033198)
0.3 2.3 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 1.2 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.7 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 1.2 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.2 4.6 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.2 2.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 2.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.2 3.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.2 2.4 GO:0019233 sensory perception of pain(GO:0019233)
0.2 2.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 2.2 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.2 0.9 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.2 1.9 GO:0046548 retinal rod cell development(GO:0046548)
0.2 1.1 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.2 0.8 GO:1903146 regulation of mitophagy(GO:1903146)
0.2 0.8 GO:0021744 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.1 0.6 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 1.0 GO:0044539 very long-chain fatty acid catabolic process(GO:0042760) long-chain fatty acid import(GO:0044539)
0.1 5.0 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 3.9 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.1 1.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.8 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 1.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.7 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 1.3 GO:0046849 bone remodeling(GO:0046849)
0.1 1.3 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 1.3 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 1.2 GO:0042044 fluid transport(GO:0042044)
0.1 0.9 GO:0044211 CTP salvage(GO:0044211)
0.1 0.8 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.4 GO:1900136 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 2.6 GO:0070831 basement membrane assembly(GO:0070831)
0.1 2.0 GO:0030316 osteoclast differentiation(GO:0030316)
0.1 5.4 GO:0003146 heart jogging(GO:0003146)
0.1 0.6 GO:0006211 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857)
0.1 3.6 GO:0021854 hypothalamus development(GO:0021854)
0.1 0.7 GO:0042438 melanin biosynthetic process(GO:0042438)
0.1 0.7 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.9 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 1.1 GO:0032264 IMP salvage(GO:0032264)
0.1 0.4 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 1.2 GO:0016203 muscle attachment(GO:0016203)
0.1 0.4 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 0.3 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.1 2.2 GO:0061386 closure of optic fissure(GO:0061386)
0.1 2.4 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 1.8 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.1 1.4 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.6 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 2.8 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 0.8 GO:0021754 facial nucleus development(GO:0021754)
0.1 0.4 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.1 0.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 1.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 0.4 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.1 0.8 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.1 GO:0051148 negative regulation of muscle cell differentiation(GO:0051148)
0.1 1.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 2.6 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.3 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.8 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.9 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.6 GO:0010458 exit from mitosis(GO:0010458)
0.0 0.2 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 1.9 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 1.6 GO:0010675 regulation of cellular carbohydrate metabolic process(GO:0010675)
0.0 1.2 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 2.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.0 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 3.7 GO:0048738 cardiac muscle tissue development(GO:0048738)
0.0 3.1 GO:0006956 complement activation(GO:0006956)
0.0 0.3 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.9 GO:0007340 acrosome reaction(GO:0007340)
0.0 3.3 GO:0021782 glial cell development(GO:0021782)
0.0 1.5 GO:0007254 JNK cascade(GO:0007254)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 3.9 GO:0003015 heart process(GO:0003015)
0.0 0.2 GO:0001843 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 0.2 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.3 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 1.5 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.5 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.2 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.8 GO:0009612 response to mechanical stimulus(GO:0009612)
0.0 1.2 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 1.9 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.5 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.4 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 4.6 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.0 GO:2000639 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 1.2 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.2 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 1.6 GO:0006413 translational initiation(GO:0006413)
0.0 1.5 GO:0051260 protein homooligomerization(GO:0051260)
0.0 1.7 GO:0014032 neural crest cell development(GO:0014032)
0.0 2.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.9 GO:0007030 Golgi organization(GO:0007030)
0.0 0.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 4.8 GO:0007507 heart development(GO:0007507)
0.0 0.7 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 6.8 GO:0016567 protein ubiquitination(GO:0016567)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.4 6.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.4 4.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.4 1.1 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.4 1.4 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.3 1.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 8.5 GO:0031672 A band(GO:0031672)
0.2 0.9 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 4.2 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2 0.7 GO:0043514 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.2 2.8 GO:0071564 npBAF complex(GO:0071564)
0.1 1.5 GO:0042583 chromaffin granule(GO:0042583)
0.1 5.4 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 1.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 2.6 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 0.4 GO:0097519 DNA recombinase complex(GO:0097519)
0.1 2.1 GO:0045180 basal cortex(GO:0045180)
0.1 3.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 9.1 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 3.7 GO:0030426 growth cone(GO:0030426)
0.1 1.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.6 GO:0005771 multivesicular body(GO:0005771)
0.1 6.4 GO:0014069 postsynaptic density(GO:0014069)
0.1 1.3 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.2 GO:0005902 microvillus(GO:0005902)
0.0 1.0 GO:0043195 terminal bouton(GO:0043195)
0.0 2.7 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 4.2 GO:0034703 cation channel complex(GO:0034703)
0.0 1.4 GO:0055037 recycling endosome(GO:0055037)
0.0 1.2 GO:0042383 sarcolemma(GO:0042383)
0.0 0.1 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.0 2.3 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.1 GO:0016342 catenin complex(GO:0016342)
0.0 1.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.3 GO:0005884 actin filament(GO:0005884)
0.0 6.4 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.8 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 10.8 GO:0043005 neuron projection(GO:0043005)
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 3.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.0 GO:0005912 adherens junction(GO:0005912)
0.0 4.5 GO:0009986 cell surface(GO:0009986)
0.0 1.6 GO:0005759 mitochondrial matrix(GO:0005759)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.7 7.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 2.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.4 4.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.4 5.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.4 2.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 1.3 GO:0071253 connexin binding(GO:0071253)
0.3 6.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.3 6.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 2.4 GO:0004985 opioid receptor activity(GO:0004985)
0.3 3.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 1.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 3.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 4.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 2.4 GO:0005042 netrin receptor activity(GO:0005042)
0.2 1.2 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.2 2.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 1.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 1.4 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.2 1.4 GO:0005035 death receptor activity(GO:0005035)
0.2 4.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 0.7 GO:0019972 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.2 0.7 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.2 2.9 GO:0048495 Roundabout binding(GO:0048495)
0.2 0.6 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 2.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 0.8 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 1.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 1.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.0 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.4 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 3.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 2.2 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 3.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 1.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 1.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.8 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 5.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.9 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 2.5 GO:0031267 small GTPase binding(GO:0031267)
0.1 1.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.1 1.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 1.2 GO:0043495 protein anchor(GO:0043495)
0.1 1.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 2.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 3.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.9 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.3 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.1 1.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.3 GO:0035497 cAMP response element binding(GO:0035497)
0.1 6.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.3 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 2.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.1 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.6 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 2.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 3.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 2.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 2.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.8 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 4.3 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.7 GO:0005501 retinoid binding(GO:0005501) isoprenoid binding(GO:0019840)
0.0 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.9 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 4.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.8 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 1.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 2.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 14.2 GO:0003779 actin binding(GO:0003779)
0.0 3.5 GO:0005125 cytokine activity(GO:0005125)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 3.8 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.6 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 1.8 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0098632 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 2.0 GO:0042802 identical protein binding(GO:0042802)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 2.6 PID CONE PATHWAY Visual signal transduction: Cones
0.1 2.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 0.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 4.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 2.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 2.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.5 4.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 3.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 1.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 2.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 1.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 2.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.4 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.1 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase