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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for myb+mybl1

Z-value: 1.65

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Transcription factors associated with myb+mybl1

Gene Symbol Gene ID Gene Info
mybl1
ENSDARG00000030999 v-myb avian myeloblastosis viral oncogene homolog-like 1
myb
ENSDARG00000053666 v-myb avian myeloblastosis viral oncogene homolog
myb
ENSDARG00000114024 v-myb avian myeloblastosis viral oncogene homolog

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mybl1dr11_v1_chr24_+_23791758_237918390.559.0e-09Click!
mybdr11_v1_chr23_+_31815423_318154920.046.9e-01Click!

Activity profile of myb+mybl1 motif

Sorted Z-values of myb+mybl1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_7974155 17.82 ENSDART00000147368
ENSDART00000075524
osbp2
oxysterol binding protein 2
chr7_+_29148714 17.17 ENSDART00000170342
mtbl
metallothionein-B-like
chr12_+_9880493 14.95 ENSDART00000055019
ndufa4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4
chr10_+_21576909 14.16 ENSDART00000168604
ENSDART00000166533
pcdh1a3
protocadherin 1 alpha 3
chr11_-_6188413 14.15 ENSDART00000109972
ccl44
chemokine (C-C motif) ligand 44
chr19_-_3240605 13.86 ENSDART00000105168
si:ch211-133n4.4
si:ch211-133n4.4
chr24_-_4973765 13.81 ENSDART00000127597
zic1
zic family member 1 (odd-paired homolog, Drosophila)
chr13_-_27660955 13.69 ENSDART00000188651
ENSDART00000134494
rims1a
regulating synaptic membrane exocytosis 1a
chr1_+_36436936 13.40 ENSDART00000124112
pou4f2
POU class 4 homeobox 2
chr25_-_20381271 13.16 ENSDART00000142665
kctd15a
potassium channel tetramerization domain containing 15a
chr3_+_19609638 12.88 ENSDART00000079319
rprml
reprimo-like
chr20_-_53981626 12.18 ENSDART00000023550
hsp90aa1.2
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2
chr24_-_7699356 12.15 ENSDART00000013117
syt5b
synaptotagmin Vb
chr11_+_36989696 12.13 ENSDART00000045888
tkta
transketolase a
chr5_-_24000211 11.99 ENSDART00000188865
map7d2a
MAP7 domain containing 2a
chr11_-_101758 11.40 ENSDART00000173015
elmo2
engulfment and cell motility 2
chr5_-_45773776 11.34 ENSDART00000124336
slc4a4a
solute carrier family 4 (sodium bicarbonate cotransporter), member 4a
chr17_-_45552602 11.07 ENSDART00000154844
ENSDART00000034432
susd4
sushi domain containing 4
chr16_+_22618620 10.84 ENSDART00000185728
ENSDART00000041625
chrnb2b
cholinergic receptor, nicotinic, beta 2b
chr7_+_71547981 10.80 ENSDART00000012070
adcyap1a
adenylate cyclase activating polypeptide 1a
chr12_+_42436920 10.80 ENSDART00000177303
ebf3a
early B cell factor 3a
chr16_-_29458806 10.80 ENSDART00000047931
lingo4b
leucine rich repeat and Ig domain containing 4b
chr10_+_20128267 10.70 ENSDART00000064615
dmtn
dematin actin binding protein
chr7_-_49646251 10.51 ENSDART00000193674
hrasb
-Ha-ras Harvey rat sarcoma viral oncogene homolog b
chr3_+_46459540 10.45 ENSDART00000188150
si:ch211-66e2.5
si:ch211-66e2.5
chr5_-_32424402 10.42 ENSDART00000077549
ncs1a
neuronal calcium sensor 1a
chr17_-_20711735 10.42 ENSDART00000150056
ank3b
ankyrin 3b
chr11_+_14622379 9.85 ENSDART00000112589
efna2b
ephrin-A2b
chr11_-_13341483 9.70 ENSDART00000164978
mast3b
microtubule associated serine/threonine kinase 3b
chr1_-_40608392 9.65 ENSDART00000101671
clgn
calmegin
chr19_+_8144556 9.51 ENSDART00000027274
ENSDART00000147218
efna3a
ephrin-A3a
chr10_+_11038192 9.50 ENSDART00000047954
ugcg
UDP-glucose ceramide glucosyltransferase
chr6_+_18569453 9.27 ENSDART00000171338
rhot1b
ras homolog family member T1
chr24_+_32472155 8.97 ENSDART00000098859
neurod6a
neuronal differentiation 6a
chr25_-_16666886 8.93 ENSDART00000155764
slc25a18
solute carrier family 25 (glutamate carrier), member 18
chr21_-_12036134 8.90 ENSDART00000031658
tpgs2
tubulin polyglutamylase complex subunit 2
chr18_-_50766660 8.89 ENSDART00000170663
ENSDART00000168601
zgc:158464
zgc:158464
chr5_-_46980651 8.85 ENSDART00000181022
ENSDART00000168038
edil3a
EGF-like repeats and discoidin I-like domains 3a
chr16_+_45456066 8.77 ENSDART00000093365
syngap1b
synaptic Ras GTPase activating protein 1b
chr1_+_27808916 8.72 ENSDART00000102335
pspc1
paraspeckle component 1
chr25_+_13791627 8.63 ENSDART00000159278
zgc:92873
zgc:92873
chr17_-_2386569 8.54 ENSDART00000121614
PLCB2
phospholipase C beta 2
chr13_+_46718518 8.42 ENSDART00000160401
ENSDART00000182884
tmem63ba
transmembrane protein 63Ba
chr5_-_23999777 8.35 ENSDART00000085969
map7d2a
MAP7 domain containing 2a
chr7_+_71547747 8.27 ENSDART00000180869
adcyap1a
adenylate cyclase activating polypeptide 1a
chr11_-_36957127 8.26 ENSDART00000168528
cacna1da
calcium channel, voltage-dependent, L type, alpha 1D subunit, a
chr17_-_33716688 8.22 ENSDART00000043651
dnal1
dynein, axonemal, light chain 1
chr19_+_21266008 8.09 ENSDART00000024639
tshz1
teashirt zinc finger homeobox 1
chr20_-_20930926 8.08 ENSDART00000123909
btbd6b
BTB (POZ) domain containing 6b
chr9_-_41277347 8.06 ENSDART00000181213
glsb
glutaminase b
chr23_-_36724575 7.92 ENSDART00000159560
agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr24_-_25574967 7.88 ENSDART00000189828
cnksr2a
connector enhancer of kinase suppressor of Ras 2a
chr3_+_51563695 7.74 ENSDART00000008607
ttyh2l
tweety homolog 2, like
chr1_+_14073891 7.74 ENSDART00000021693
ank2a
ankyrin 2a, neuronal
chr21_-_38717854 7.73 ENSDART00000065169
ENSDART00000113813
siah2l
seven in absentia homolog 2 (Drosophila)-like
chr3_-_36115339 7.59 ENSDART00000187406
ENSDART00000123505
ENSDART00000151775
rab11fip4a
RAB11 family interacting protein 4 (class II) a
chr17_-_37156520 7.57 ENSDART00000145669
dtnbb
dystrobrevin, beta b
chr6_-_40744720 7.22 ENSDART00000154916
ENSDART00000186922
p4htm
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr6_-_18128721 7.20 ENSDART00000160036
SEC14L1
si:dkey-237i9.1
chr24_-_35707552 7.12 ENSDART00000165199
mapre2
microtubule-associated protein, RP/EB family, member 2
chr20_-_45423498 7.07 ENSDART00000098424
trib2
tribbles pseudokinase 2
chr19_-_28789404 6.89 ENSDART00000191453
ENSDART00000026992
sox4a
SRY (sex determining region Y)-box 4a
chr24_-_37472727 6.89 ENSDART00000134152
cluap1
clusterin associated protein 1
chr25_-_518656 6.79 ENSDART00000156421
myo9ab
myosin IXAb
chr10_+_10636237 6.71 ENSDART00000136853
fam163b
family with sequence similarity 163, member B
chr22_+_28803739 6.69 ENSDART00000129476
ENSDART00000189726
tp53bp2b
tumor protein p53 binding protein, 2b
chr2_-_11662851 6.66 ENSDART00000145108
zgc:110130
zgc:110130
chr9_-_30808073 6.57 ENSDART00000146300
klf5b
Kruppel-like factor 5b
chr15_-_26887028 6.55 ENSDART00000156292
si:dkey-243i1.1
si:dkey-243i1.1
chr12_+_9761685 6.55 ENSDART00000189522
ppp1r9bb
protein phosphatase 1, regulatory subunit 9Bb
chr8_+_14381272 6.50 ENSDART00000057642
acbd6
acyl-CoA binding domain containing 6
chr1_-_44704261 6.48 ENSDART00000133210
si:dkey-28b4.8
si:dkey-28b4.8
chr8_+_29749017 6.37 ENSDART00000185144
mapk4
mitogen-activated protein kinase 4
chr20_+_34596954 6.36 ENSDART00000076946
si:ch211-242b18.1
si:ch211-242b18.1
chr5_-_66749535 6.34 ENSDART00000132183
kat5b
K(lysine) acetyltransferase 5b
chr10_+_2234283 6.32 ENSDART00000136363
cntnap3
contactin associated protein like 3
chr3_-_59981476 6.23 ENSDART00000035878
ENSDART00000124038
cdr2l
cerebellar degeneration-related protein 2-like
chr17_+_23938283 6.22 ENSDART00000184391
si:ch211-189k9.2
si:ch211-189k9.2
chr19_-_32944050 6.22 ENSDART00000137611
azin1b
antizyme inhibitor 1b
chr2_-_16224083 6.17 ENSDART00000165953
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr10_+_34685135 6.17 ENSDART00000184999
nbeaa
neurobeachin a
chr6_-_30658755 6.17 ENSDART00000065215
ENSDART00000181302
lurap1
leucine rich adaptor protein 1
chr9_-_24209083 6.15 ENSDART00000134599
zgc:153521
zgc:153521
chr24_-_28437833 6.03 ENSDART00000125412
fbxo45
F-box protein 45
chr10_-_25860102 6.02 ENSDART00000080789
trpc4a
transient receptor potential cation channel, subfamily C, member 4a
chr15_+_36977208 5.97 ENSDART00000183625
kirrel3l
kirre like nephrin family adhesion molecule 3, like
chr18_+_7639401 5.95 ENSDART00000092416
rabl2
RAB, member of RAS oncogene family-like 2
chr7_+_56253914 5.90 ENSDART00000073594
ankrd11
ankyrin repeat domain 11
chr9_+_44397151 5.90 ENSDART00000185947
ssfa2
sperm specific antigen 2
chr23_+_22335407 5.90 ENSDART00000147696
rap1gap
RAP1 GTPase activating protein
chr21_-_17482465 5.90 ENSDART00000004548
barhl1b
BarH-like homeobox 1b
chr8_-_14080534 5.82 ENSDART00000042867
dedd
death effector domain containing
chr13_-_33009734 5.74 ENSDART00000134140
rbm25a
RNA binding motif protein 25a
chr22_-_20342260 5.72 ENSDART00000161610
ENSDART00000165667
tcf3b
transcription factor 3b
chr15_+_29393519 5.69 ENSDART00000193488
ENSDART00000112375
gdpd5b
glycerophosphodiester phosphodiesterase domain containing 5b
chr11_+_38280454 5.68 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr15_-_23942861 5.62 ENSDART00000002824
appbp2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr14_-_33083539 5.62 ENSDART00000160173
dlg3
discs, large homolog 3 (Drosophila)
chr25_-_20666328 5.58 ENSDART00000098076
csk
C-terminal Src kinase
chr24_-_33780387 5.57 ENSDART00000079210
cdk5
cyclin-dependent kinase 5
chr13_-_23756700 5.55 ENSDART00000057612
rgs17
regulator of G protein signaling 17
chr22_+_24157807 5.51 ENSDART00000159165
b3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr11_+_16152316 5.47 ENSDART00000081054
tada3l
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr4_-_8611841 5.46 ENSDART00000067322
fbxl14b
F-box and leucine-rich repeat protein 14b
chr7_+_63324888 5.45 ENSDART00000147785
pcdh7b
protocadherin 7b
chr3_+_39853788 5.45 ENSDART00000154869
cacna1ha
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr17_+_5846202 5.43 ENSDART00000189713
fndc4b
fibronectin type III domain containing 4b
chr23_+_28092083 5.42 ENSDART00000053958
c1galt1a
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a
chr7_+_20109968 5.41 ENSDART00000146335
zgc:114045
zgc:114045
chr17_+_10593398 5.40 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mapkbp1
mitogen-activated protein kinase binding protein 1
chr23_-_7125494 5.36 ENSDART00000111929
slco4a1
solute carrier organic anion transporter family, member 4A1
chr17_+_21818093 5.36 ENSDART00000125335
ikzf5
IKAROS family zinc finger 5
chr5_+_21931124 5.35 ENSDART00000137627
si:ch73-92i20.1
si:ch73-92i20.1
chr1_+_18863060 5.32 ENSDART00000139241
rnf38
ring finger protein 38
chr6_-_22369125 5.27 ENSDART00000083038
nprl2
NPR2 like, GATOR1 complex subunit
chr16_-_29164379 5.26 ENSDART00000132589
mef2d
myocyte enhancer factor 2d
chr18_-_29972709 5.26 ENSDART00000131207
si:ch211-220f16.2
si:ch211-220f16.2
chr19_-_10810006 5.20 ENSDART00000151157
si:dkey-3n22.9
si:dkey-3n22.9
chr18_-_16937008 5.16 ENSDART00000100117
ENSDART00000022640
ENSDART00000136541
znf143b
zinc finger protein 143b
chr7_-_20756013 5.15 ENSDART00000185259
chd3
chromodomain helicase DNA binding protein 3
chr4_-_7811925 5.12 ENSDART00000103070
cdk17
cyclin-dependent kinase 17
chr20_-_3390406 5.12 ENSDART00000136987
rev3l
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr19_+_2602903 4.99 ENSDART00000033132
fam126a
family with sequence similarity 126, member A
chr17_+_18117358 4.98 ENSDART00000144894
bcl11ba
B cell CLL/lymphoma 11Ba
chr1_+_12763920 4.95 ENSDART00000189465
pcdh10a
protocadherin 10a
chr23_+_36616717 4.92 ENSDART00000042701
ENSDART00000192980
pip4k2ca
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a
chr5_+_25304499 4.90 ENSDART00000163425
carnmt1
carnosine N-methyltransferase 1
chr11_-_13341051 4.80 ENSDART00000121872
mast3b
microtubule associated serine/threonine kinase 3b
chr21_-_26691959 4.78 ENSDART00000149702
ENSDART00000149840
bscl2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr20_-_18731268 4.74 ENSDART00000183893
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr2_+_46032678 4.73 ENSDART00000184382
ENSDART00000125971
gpc1b
glypican 1b
chr7_+_53754653 4.70 ENSDART00000163261
ENSDART00000158160
neo1a
neogenin 1a
chr18_+_15132112 4.66 ENSDART00000099764
zgc:153031
zgc:153031
chr12_+_40810418 4.65 ENSDART00000183393
CDH18
cadherin 18
chr4_-_39111612 4.64 ENSDART00000150394
si:dkey-122c11.8
si:dkey-122c11.8
chr11_-_36263886 4.64 ENSDART00000140397
nfya
nuclear transcription factor Y, alpha
chr8_+_22289320 4.61 ENSDART00000075126
b3gnt7l
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7, like
chr1_-_46718353 4.54 ENSDART00000074514
spryd7a
SPRY domain containing 7a
chr1_-_45920632 4.54 ENSDART00000140890
pnpla6
patatin-like phospholipase domain containing 6
chr24_+_4978055 4.53 ENSDART00000045813
zic4
zic family member 4
chr21_+_33249478 4.51 ENSDART00000169972
si:ch211-151g22.1
si:ch211-151g22.1
chr9_+_7456076 4.49 ENSDART00000125824
ENSDART00000122526
tmem198a
transmembrane protein 198a
chr22_-_22259175 4.45 ENSDART00000113824
hdgfl2
HDGF like 2
chr19_+_10831362 4.41 ENSDART00000053325
tomm40l
translocase of outer mitochondrial membrane 40 homolog, like
chr3_-_12890670 4.37 ENSDART00000159934
ENSDART00000188607
btbd17b
BTB (POZ) domain containing 17b
chr16_-_23379464 4.37 ENSDART00000045891
trim46a
tripartite motif containing 46a
chr1_-_44701313 4.35 ENSDART00000193926
si:dkey-28b4.8
si:dkey-28b4.8
chr24_-_25673405 4.32 ENSDART00000186081
ENSDART00000110241
ENSDART00000142351
cnksr2a
connector enhancer of kinase suppressor of Ras 2a
chr17_+_41302660 4.31 ENSDART00000059480
fosl2
fos-like antigen 2
chr12_+_11650146 4.27 ENSDART00000150191
waplb
WAPL cohesin release factor b
chr9_-_31915423 4.21 ENSDART00000060051
fgf14
fibroblast growth factor 14
chr20_-_4738101 4.18 ENSDART00000050201
ENSDART00000152559
ENSDART00000053858
ENSDART00000125620
papola
poly(A) polymerase alpha
chr12_+_17436904 4.16 ENSDART00000079130
atad1b
ATPase family, AAA domain containing 1b
chr22_+_34430310 4.16 ENSDART00000109860
amigo3
adhesion molecule with Ig-like domain 3
chr11_+_41560792 4.13 ENSDART00000127292
kcnab2a
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr22_-_16658996 4.11 ENSDART00000138429
si:dkey-38n4.2
si:dkey-38n4.2
chr15_+_16525126 4.11 ENSDART00000193455
galnt17
polypeptide N-acetylgalactosaminyltransferase 17
chr16_-_21047483 4.10 ENSDART00000136235
cbx3b
chromobox homolog 3b
chr24_-_12749116 4.10 ENSDART00000093583
cox19
COX19 cytochrome c oxidase assembly factor
chr15_+_3219134 4.09 ENSDART00000113532
LO017656.1

chr4_+_30363474 4.08 ENSDART00000168421
si:dkey-199m13.7
si:dkey-199m13.7
chr17_+_23968214 4.08 ENSDART00000183053
xpo1b
exportin 1 (CRM1 homolog, yeast) b
chr15_+_4988189 4.05 ENSDART00000142995
ENSDART00000062852
spcs2
signal peptidase complex subunit 2
chr5_-_35953472 4.03 ENSDART00000143448
rxfp2l
relaxin/insulin-like family peptide receptor 2, like
chr22_-_25033105 4.01 ENSDART00000124220
nptxrb
neuronal pentraxin receptor b
chr18_-_47533692 4.00 ENSDART00000191097
CABZ01112461.1

chr15_+_15786160 3.96 ENSDART00000130670
ENSDART00000090939
tada2a
transcriptional adaptor 2A
chr11_-_472547 3.96 ENSDART00000005923
zgc:77375
zgc:77375
chr3_-_56889052 3.94 ENSDART00000188412
ush1ga
Usher syndrome 1Ga (autosomal recessive)
chr17_+_21817859 3.92 ENSDART00000143832
ENSDART00000141462
ikzf5
IKAROS family zinc finger 5
chr10_+_21737745 3.89 ENSDART00000170498
ENSDART00000167997
pcdh1g18
protocadherin 1 gamma 18
chr5_+_20147830 3.82 ENSDART00000098727
svopa
SV2 related protein a
chr14_-_33177935 3.81 ENSDART00000180583
ENSDART00000078856
dlg3
discs, large homolog 3 (Drosophila)
chr7_+_7151832 3.80 ENSDART00000109485
gal3st3
galactose-3-O-sulfotransferase 3
chr23_+_23187442 3.78 ENSDART00000184920
klhl17
kelch-like family member 17
chr14_-_33081784 3.73 ENSDART00000165726
dlg3
discs, large homolog 3 (Drosophila)
chr25_+_27744293 3.69 ENSDART00000103519
ENSDART00000149456
wasla
Wiskott-Aldrich syndrome-like a
chr7_+_50766094 3.67 ENSDART00000165037
si:ch73-380l10.2
si:ch73-380l10.2
chr6_-_24392909 3.66 ENSDART00000171042
ENSDART00000168355
brdt
bromodomain, testis-specific
chr5_-_67267678 3.65 ENSDART00000156795
ENSDART00000125781
ENSDART00000125874
zcchc8
zinc finger, CCHC domain containing 8
chr16_+_10422836 3.59 ENSDART00000161568
ino80e
INO80 complex subunit E
chr16_+_32238020 3.58 ENSDART00000017562
klhl32
kelch-like family member 32
chr19_+_41701660 3.54 ENSDART00000033362
gatad2b
GATA zinc finger domain containing 2B
chr22_-_8174244 3.53 ENSDART00000156571
si:ch73-44m9.3
si:ch73-44m9.3
chr5_+_31983098 3.53 ENSDART00000007458
ppp6c
protein phosphatase 6, catalytic subunit
chr6_-_44711942 3.52 ENSDART00000055035
cntn3b
contactin 3b
chr10_+_5135842 3.50 ENSDART00000132627
ENSDART00000162434
zgc:113274
zgc:113274
chr1_+_41596099 3.48 ENSDART00000111367
si:dkey-56e3.3
si:dkey-56e3.3
chr3_+_17456428 3.48 ENSDART00000090676
ENSDART00000182082
si:ch211-210g13.5
si:ch211-210g13.5
chr16_+_5612547 3.46 ENSDART00000140226
ENSDART00000189352
CYTH2
si:dkey-283b15.4
chr2_+_35240485 3.46 ENSDART00000179804
tnr
tenascin R (restrictin, janusin)
chr19_-_38872650 3.45 ENSDART00000146641
adgrb2
adhesion G protein-coupled receptor B2
chr11_+_21910752 3.42 ENSDART00000114288
foxp4
forkhead box P4
chr11_-_36156935 3.40 ENSDART00000124935
ENSDART00000138609
brk1
gpx1a
BRICK1, SCAR/WAVE actin-nucleating complex subunit
glutathione peroxidase 1a
chr10_-_28368913 3.39 ENSDART00000063849
cltca
clathrin, heavy chain a (Hc)
chr9_-_10532591 3.39 ENSDART00000175269
thsd7ba
thrombospondin, type I, domain containing 7Ba
chr1_+_19434198 3.38 ENSDART00000012552
clockb
clock circadian regulator b
chr17_+_30749251 3.35 ENSDART00000115296
ldah
lipid droplet associated hydrolase
chr11_+_24816238 3.33 ENSDART00000115356
rabif
RAB interacting factor
chr15_-_13254480 3.32 ENSDART00000190499
zgc:172282
zgc:172282

Network of associatons between targets according to the STRING database.

First level regulatory network of myb+mybl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
3.2 9.5 GO:0006678 glucosylceramide metabolic process(GO:0006678)
2.6 18.3 GO:0021534 cell proliferation in hindbrain(GO:0021534)
2.4 12.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
2.0 6.1 GO:0051037 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
1.9 9.5 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
1.5 9.3 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
1.4 4.3 GO:0060623 regulation of chromosome condensation(GO:0060623)
1.4 5.4 GO:0016267 O-glycan processing, core 1(GO:0016267)
1.2 7.4 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
1.2 10.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
1.2 25.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
1.2 4.7 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
1.1 5.6 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
1.1 12.2 GO:0034605 cellular response to heat(GO:0034605)
1.0 3.1 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
1.0 8.1 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.9 8.9 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.9 4.3 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.8 7.1 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.7 2.2 GO:0032637 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.7 6.7 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.7 10.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.7 12.2 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.7 2.8 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.7 20.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.7 4.8 GO:0034389 lipid particle organization(GO:0034389)
0.7 6.0 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.7 2.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.6 8.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.6 19.1 GO:0030073 insulin secretion(GO:0030073)
0.6 4.0 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.6 5.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.6 3.4 GO:0010269 response to selenium ion(GO:0010269)
0.6 6.2 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.5 9.3 GO:0051654 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) establishment of mitochondrion localization(GO:0051654)
0.5 4.3 GO:1905207 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.5 12.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.5 2.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.5 4.0 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.5 11.3 GO:0015701 bicarbonate transport(GO:0015701)
0.5 5.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.5 8.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.4 4.0 GO:0006465 signal peptide processing(GO:0006465)
0.4 3.1 GO:0000492 box C/D snoRNP assembly(GO:0000492) regulation of heart growth(GO:0060420)
0.4 12.0 GO:0032836 glomerular basement membrane development(GO:0032836)
0.4 10.4 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.4 18.0 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.4 14.2 GO:0060037 pharyngeal system development(GO:0060037)
0.4 4.7 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.4 10.4 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.4 3.3 GO:0060872 semicircular canal development(GO:0060872)
0.4 5.4 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.4 2.9 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.4 5.3 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.3 14.1 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.3 13.2 GO:0097120 receptor localization to synapse(GO:0097120)
0.3 4.0 GO:0030819 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.3 4.5 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.3 4.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.3 1.5 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.3 4.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.3 4.9 GO:0097324 melanocyte migration(GO:0097324)
0.3 3.4 GO:0009648 photoperiodism(GO:0009648)
0.3 1.4 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.3 1.6 GO:0002279 mast cell activation involved in immune response(GO:0002279) mast cell mediated immunity(GO:0002448) regulation of mast cell activation(GO:0033003) regulation of mast cell activation involved in immune response(GO:0033006) leukocyte degranulation(GO:0043299) regulation of leukocyte degranulation(GO:0043300) mast cell degranulation(GO:0043303) regulation of mast cell degranulation(GO:0043304)
0.3 2.3 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.2 5.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.2 1.7 GO:0048569 post-embryonic organ development(GO:0048569)
0.2 3.7 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 1.7 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 1.7 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 10.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.2 4.7 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.2 4.1 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2 6.0 GO:0006828 manganese ion transport(GO:0006828)
0.2 4.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 1.7 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.2 6.5 GO:0007099 centriole replication(GO:0007099)
0.2 6.9 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.2 5.7 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.2 1.2 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 8.6 GO:0048854 brain morphogenesis(GO:0048854)
0.2 4.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.2 7.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 5.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.2 1.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 10.1 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.2 1.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.2 2.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.2 3.5 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.2 2.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 2.3 GO:0016199 axon midline choice point recognition(GO:0016199)
0.2 2.6 GO:0046549 retinal cone cell development(GO:0046549)
0.2 0.6 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.2 2.9 GO:0018345 protein palmitoylation(GO:0018345)
0.1 7.1 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1 6.2 GO:0007416 synapse assembly(GO:0007416)
0.1 2.0 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.1 1.3 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.1 2.9 GO:0034453 microtubule anchoring(GO:0034453)
0.1 3.2 GO:0097194 execution phase of apoptosis(GO:0097194)
0.1 3.8 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.1 1.3 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.6 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 4.9 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 2.9 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 2.8 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 2.0 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 3.4 GO:0019915 lipid storage(GO:0019915)
0.1 3.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 2.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.4 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.1 1.0 GO:0021794 thalamus development(GO:0021794)
0.1 2.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 3.5 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 24.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.4 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.1 5.2 GO:0016575 histone deacetylation(GO:0016575)
0.1 5.0 GO:0046834 lipid phosphorylation(GO:0046834)
0.1 5.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 1.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 1.7 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 7.4 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1 2.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 3.5 GO:0048017 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.1 9.0 GO:0050769 positive regulation of neurogenesis(GO:0050769)
0.1 3.7 GO:0003401 axis elongation(GO:0003401)
0.1 6.2 GO:0046474 glycerophospholipid biosynthetic process(GO:0046474)
0.1 1.1 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 2.8 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.1 1.6 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 1.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 4.5 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.1 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.3 GO:0055016 hypochord development(GO:0055016)
0.1 3.3 GO:0016573 histone acetylation(GO:0016573)
0.1 1.8 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 1.6 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.1 5.8 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 3.2 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 1.0 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.5 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.9 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 11.4 GO:0010876 lipid localization(GO:0010876)
0.0 0.5 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 1.4 GO:0032456 endocytic recycling(GO:0032456)
0.0 3.5 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 4.1 GO:0006338 chromatin remodeling(GO:0006338)
0.0 10.5 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 1.9 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 1.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.7 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 1.2 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 16.1 GO:0001944 vasculature development(GO:0001944)
0.0 1.4 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 13.6 GO:0007420 brain development(GO:0007420)
0.0 3.6 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.2 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 7.1 GO:0098609 cell-cell adhesion(GO:0098609)
0.0 9.5 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 4.8 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.1 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 2.1 GO:0006413 translational initiation(GO:0006413)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 1.0 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 2.5 GO:0050767 regulation of neurogenesis(GO:0050767)
0.0 0.5 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 0.1 GO:0010939 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544) negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.0 0.8 GO:0070509 calcium ion import(GO:0070509)
0.0 0.3 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 1.4 GO:0016197 endosomal transport(GO:0016197)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.8 GO:0071439 clathrin complex(GO:0071439)
1.0 12.2 GO:0031045 dense core granule(GO:0031045)
1.0 4.0 GO:0005787 signal peptidase complex(GO:0005787)
0.8 3.1 GO:0097255 R2TP complex(GO:0097255)
0.8 5.3 GO:1990130 Iml1 complex(GO:1990130)
0.7 9.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.7 12.2 GO:0043209 myelin sheath(GO:0043209)
0.7 3.4 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.6 5.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.5 8.7 GO:0016363 nuclear matrix(GO:0016363)
0.5 13.7 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.5 19.1 GO:0043204 perikaryon(GO:0043204)
0.4 6.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.4 4.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.4 4.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.4 5.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.4 6.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.4 24.1 GO:0031225 anchored component of membrane(GO:0031225)
0.4 6.3 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.4 1.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.3 9.1 GO:0035371 microtubule plus-end(GO:0035371)
0.3 4.8 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.3 4.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 6.7 GO:0009925 basal plasma membrane(GO:0009925)
0.3 2.7 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.3 2.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 4.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 2.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 5.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.2 4.0 GO:0070461 SAGA-type complex(GO:0070461)
0.2 19.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 3.4 GO:0031209 SCAR complex(GO:0031209)
0.2 3.6 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 7.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 2.0 GO:0005688 U6 snRNP(GO:0005688)
0.2 2.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 3.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 2.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 9.5 GO:0030426 growth cone(GO:0030426)
0.2 5.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.2 2.5 GO:0005682 U5 snRNP(GO:0005682)
0.2 3.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 2.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 12.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 2.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 1.7 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 7.7 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.9 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.1 5.9 GO:0030286 dynein complex(GO:0030286)
0.1 2.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 3.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 5.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 3.5 GO:0031902 late endosome membrane(GO:0031902)
0.1 8.4 GO:0034703 cation channel complex(GO:0034703)
0.1 2.6 GO:0005811 lipid particle(GO:0005811)
0.1 6.5 GO:0014069 postsynaptic density(GO:0014069)
0.0 4.7 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.9 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 1.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.6 GO:0030667 secretory granule membrane(GO:0030667)
0.0 3.7 GO:0005884 actin filament(GO:0005884)
0.0 2.8 GO:0031201 SNARE complex(GO:0031201)
0.0 1.1 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 14.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.0 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 7.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 5.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.2 GO:0005911 cell-cell junction(GO:0005911)
0.0 1.8 GO:0005912 adherens junction(GO:0005912) anchoring junction(GO:0070161)
0.0 0.9 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 19.1 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
2.4 7.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
2.0 12.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
1.4 5.4 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
1.2 7.4 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
1.2 4.9 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
1.0 4.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
1.0 2.9 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.9 19.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.9 8.1 GO:0004359 glutaminase activity(GO:0004359)
0.9 7.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.8 11.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.8 5.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.7 8.9 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.7 10.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.7 8.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.7 9.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.7 17.8 GO:0015248 sterol transporter activity(GO:0015248)
0.6 3.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.6 4.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.6 7.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.5 2.0 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.5 3.4 GO:0070888 E-box binding(GO:0070888)
0.5 3.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.5 4.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 7.1 GO:0002039 p53 binding(GO:0002039)
0.4 5.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.4 1.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.4 3.8 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.4 9.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.4 2.2 GO:0042169 SH2 domain binding(GO:0042169)
0.4 1.5 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.3 7.6 GO:0031267 small GTPase binding(GO:0031267)
0.3 14.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 17.8 GO:0044325 ion channel binding(GO:0044325)
0.3 4.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.3 4.4 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.3 10.5 GO:0019003 GDP binding(GO:0019003)
0.3 8.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 6.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.3 3.1 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.3 8.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 12.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 3.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 2.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 22.1 GO:0051082 unfolded protein binding(GO:0051082)
0.2 8.7 GO:0004707 MAP kinase activity(GO:0004707)
0.2 3.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 3.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 5.6 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.2 10.1 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 11.4 GO:0017124 SH3 domain binding(GO:0017124)
0.2 4.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 4.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 7.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 1.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 6.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 2.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 4.7 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.2 6.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.2 3.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 8.8 GO:0005178 integrin binding(GO:0005178)
0.1 0.4 GO:0071253 connexin binding(GO:0071253)
0.1 2.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.2 GO:0004096 catalase activity(GO:0004096)
0.1 0.6 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.1 GO:0035198 miRNA binding(GO:0035198)
0.1 2.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 3.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 2.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.4 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 3.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 3.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 15.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 1.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 6.5 GO:0003678 DNA helicase activity(GO:0003678)
0.1 2.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 28.6 GO:0005096 GTPase activator activity(GO:0005096)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 12.1 GO:0000287 magnesium ion binding(GO:0000287)
0.1 5.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 3.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 5.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 4.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 7.3 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.1 1.6 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.1 0.6 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 17.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 1.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.1 1.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 5.4 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 40.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 5.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.4 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 2.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 8.8 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 0.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 2.8 GO:0000975 regulatory region DNA binding(GO:0000975) transcription regulatory region sequence-specific DNA binding(GO:0000976) regulatory region nucleic acid binding(GO:0001067) transcription regulatory region DNA binding(GO:0044212)
0.0 3.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 46.7 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 12.9 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 2.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.2 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 8.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.4 14.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.3 8.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.3 3.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.3 7.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.3 5.0 PID ARF 3PATHWAY Arf1 pathway
0.2 8.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.2 5.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 13.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.2 2.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 6.2 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.2 4.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 6.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 1.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.2 11.9 PID P73PATHWAY p73 transcription factor network
0.2 2.1 PID RHOA PATHWAY RhoA signaling pathway
0.2 2.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 8.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 6.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 2.7 PID BARD1 PATHWAY BARD1 signaling events
0.1 1.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 1.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 2.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 1.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.5 PID CMYB PATHWAY C-MYB transcription factor network
0.1 2.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 3.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.6 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.9 8.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.9 13.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.7 5.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.7 5.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.7 7.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.5 4.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4 2.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 4.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.3 2.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.3 3.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.3 5.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.3 15.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 3.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 8.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 6.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 4.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 3.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 2.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 9.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 3.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 5.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.2 2.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 1.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 3.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 2.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.1 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 3.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 0.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.1 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.1 1.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 6.0 REACTOME DNA REPAIR Genes involved in DNA Repair
0.1 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 2.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)