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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for myod1

Z-value: 2.16

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Transcription factors associated with myod1

Gene Symbol Gene ID Gene Info
myod1
ENSDARG00000030110 myogenic differentiation 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
myod1dr11_v1_chr25_-_31423493_314234930.784.2e-20Click!

Activity profile of myod1 motif

Sorted Z-values of myod1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_32817274 47.40 ENSDART00000142582
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr8_-_1051438 35.50 ENSDART00000067093
ENSDART00000170737
smyd1b
SET and MYND domain containing 1b
chr6_-_42003780 31.49 ENSDART00000032527
cav3
caveolin 3
chr3_+_32526263 29.90 ENSDART00000150897
si:ch73-367p23.2
si:ch73-367p23.2
chr2_+_55982940 28.12 ENSDART00000097753
ENSDART00000097751
nmrk2
nicotinamide riboside kinase 2
chr3_+_32526799 26.92 ENSDART00000185755
si:ch73-367p23.2
si:ch73-367p23.2
chr22_-_14128716 26.37 ENSDART00000140323
si:ch211-246m6.4
si:ch211-246m6.4
chr21_+_27382893 25.57 ENSDART00000005682
actn3a
actinin alpha 3a
chr2_+_55982300 24.42 ENSDART00000183903
nmrk2
nicotinamide riboside kinase 2
chr7_+_31891110 23.10 ENSDART00000173883
mybpc3
myosin binding protein C, cardiac
chr9_-_22831836 22.77 ENSDART00000142585
neb
nebulin
chr6_-_39764995 22.39 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr9_-_7539297 21.77 ENSDART00000081550
ENSDART00000081553
desma
desmin a
chr6_+_3680651 21.15 ENSDART00000013588
klhl41b
kelch-like family member 41b
chr12_-_4070058 20.04 ENSDART00000042200
aldoab
aldolase a, fructose-bisphosphate, b
chr8_-_11229523 19.98 ENSDART00000002164
unc45b
unc-45 myosin chaperone B
chr13_+_22264914 19.91 ENSDART00000060576
myoz1a
myozenin 1a
chr18_+_402048 19.80 ENSDART00000166345
gpib
glucose-6-phosphate isomerase b
chr9_-_98982 19.66 ENSDART00000147882
lims2
LIM and senescent cell antigen-like domains 2
chr2_-_44255537 19.48 ENSDART00000011188
ENSDART00000093298
atp1a2a
ATPase Na+/K+ transporting subunit alpha 2
chr18_-_6634424 19.27 ENSDART00000062423
ENSDART00000179955
tnni1c
troponin I, skeletal, slow c
chr7_-_69857692 18.64 ENSDART00000124764
myoz2a
myozenin 2a
chr16_-_31469065 18.35 ENSDART00000182397
si:ch211-251p5.5
si:ch211-251p5.5
chr22_-_651719 17.99 ENSDART00000148692
apobec2a
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a
chr9_-_48281941 17.89 ENSDART00000099787
klhl41a
kelch-like family member 41a
chr13_-_7031033 17.70 ENSDART00000193211
CABZ01061524.1

chr25_+_14087045 17.65 ENSDART00000155770
actc1c
actin, alpha, cardiac muscle 1c
chr2_-_21335131 17.56 ENSDART00000057022
klhl40a
kelch-like family member 40a
chr12_-_26415499 17.55 ENSDART00000185779
synpo2lb
synaptopodin 2-like b
chr17_+_27434626 17.25 ENSDART00000052446
vgll2b
vestigial-like family member 2b
chr24_-_33703504 17.20 ENSDART00000079292
cavin4b
caveolae associated protein 4b
chr6_-_39765546 17.20 ENSDART00000185767
pfkmb
phosphofructokinase, muscle b
chr7_+_39402864 16.81 ENSDART00000025852
tnni2b.1
troponin I type 2b (skeletal, fast), tandem duplicate 1
chr20_-_27325258 16.50 ENSDART00000152917
asb2a.1
ankyrin repeat and SOCS box containing 2a, tandem duplicate 1
chr20_+_26966725 16.17 ENSDART00000029781
ahsa1a
AHA1, activator of heat shock protein ATPase homolog 1a
chr14_+_31651533 15.97 ENSDART00000172835
fhl1a
four and a half LIM domains 1a
chr16_-_12723738 15.96 ENSDART00000080414
sbk3
SH3 domain binding kinase family, member 3
chr23_-_5683147 15.28 ENSDART00000102766
ENSDART00000067351
tnnt2a
troponin T type 2a (cardiac)
chr20_-_38758797 14.70 ENSDART00000061394
trim54
tripartite motif containing 54
chr7_+_31879649 13.96 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr4_+_7841627 13.84 ENSDART00000037997
ucmaa
upper zone of growth plate and cartilage matrix associated a
chr23_-_32194397 13.61 ENSDART00000184206
ENSDART00000166682
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr22_-_26595027 13.26 ENSDART00000184162
CABZ01072309.1

chr24_+_20575259 13.22 ENSDART00000010488
klhl40b
kelch-like family member 40b
chr16_-_14074594 13.10 ENSDART00000090234
trim109
tripartite motif containing 109
chr23_+_44614056 13.09 ENSDART00000188379
eno3
enolase 3, (beta, muscle)
chr22_+_16308450 12.97 ENSDART00000105678
lrrc39
leucine rich repeat containing 39
chr20_+_26967154 12.90 ENSDART00000153294
ENSDART00000132434
ENSDART00000143047
ahsa1a
AHA1, activator of heat shock protein ATPase homolog 1a
chr4_-_16354292 12.76 ENSDART00000139919
lum
lumican
chr20_-_21672970 12.75 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr14_+_31657412 12.41 ENSDART00000105767
fhl1a
four and a half LIM domains 1a
chr22_+_16308806 12.39 ENSDART00000162685
lrrc39
leucine rich repeat containing 39
chr18_+_29145681 12.30 ENSDART00000089031
ENSDART00000193336
ppfibp2a
PTPRF interacting protein, binding protein 2a (liprin beta 2)
chr3_+_49397115 12.29 ENSDART00000176042
tecra
trans-2,3-enoyl-CoA reductase a
chr7_+_31838320 12.19 ENSDART00000144679
ENSDART00000174217
ENSDART00000122506
mybpc3
myosin binding protein C, cardiac
chr7_+_31879986 12.17 ENSDART00000138491
mybpc3
myosin binding protein C, cardiac
chr2_-_42128714 12.03 ENSDART00000047055
trim55a
tripartite motif containing 55a
chr1_-_38816685 11.94 ENSDART00000075230
asb5b
ankyrin repeat and SOCS box containing 5b
chr11_-_45171139 11.85 ENSDART00000167036
ENSDART00000161712
ENSDART00000158156
syngr2b
synaptogyrin 2b
chr14_+_22113331 11.63 ENSDART00000109759
tmx2a
thioredoxin-related transmembrane protein 2a
chr12_+_18524953 11.39 ENSDART00000090332
neurl2
neuralized E3 ubiquitin protein ligase 2
chr2_-_23768818 11.11 ENSDART00000148685
ENSDART00000191167
xirp1
xin actin binding repeat containing 1
chr16_-_12723324 11.07 ENSDART00000131915
sbk3
SH3 domain binding kinase family, member 3
chr23_-_31512496 10.84 ENSDART00000158755
ENSDART00000143425
eya4
EYA transcriptional coactivator and phosphatase 4
chr6_-_21189295 10.73 ENSDART00000137136
obsl1a
obscurin-like 1a
chr4_-_16412084 10.67 ENSDART00000188460
dcn
decorin
chr23_+_6077503 10.54 ENSDART00000081714
ENSDART00000139834
mybpha
myosin binding protein Ha
chr5_-_64355227 10.18 ENSDART00000170787
fam78aa
family with sequence similarity 78, member Aa
chr14_-_25956804 9.94 ENSDART00000135627
ENSDART00000146022
ENSDART00000039660
sparc
secreted protein, acidic, cysteine-rich (osteonectin)
chr23_-_29003864 9.88 ENSDART00000148257
casz1
castor zinc finger 1
chr3_+_22242269 9.83 ENSDART00000168970
scn4ab
sodium channel, voltage-gated, type IV, alpha, b
chr19_-_5369486 9.72 ENSDART00000105004
krt17
keratin 17
chr22_-_10110959 9.68 ENSDART00000031005
ENSDART00000147580
gls2b
glutaminase 2b (liver, mitochondrial)
chr16_+_25245857 9.60 ENSDART00000155220
klhl38b
kelch-like family member 38b
chr20_-_26866111 9.14 ENSDART00000077767
mylk4b
myosin light chain kinase family, member 4b
chr13_+_23157053 9.10 ENSDART00000162359
sorbs1
sorbin and SH3 domain containing 1
chr25_-_8602437 9.07 ENSDART00000171200
rhcgb
Rh family, C glycoprotein b
chr17_+_38573471 8.99 ENSDART00000040627
sptb
spectrin, beta, erythrocytic
chr17_+_53311618 8.91 ENSDART00000166517
asb2b
ankyrin repeat and SOCS box containing 2b
chr4_-_15603511 8.90 ENSDART00000122520
ENSDART00000162356
chchd3a
coiled-coil-helix-coiled-coil-helix domain containing 3a
chr16_-_29146624 8.84 ENSDART00000159814
ENSDART00000009826
mef2d
myocyte enhancer factor 2d
chr1_-_10841348 8.82 ENSDART00000148305
dmd
dystrophin
chr25_+_16214854 8.75 ENSDART00000109672
ENSDART00000190093
mical2b
microtubule associated monooxygenase, calponin and LIM domain containing 2b
chr24_+_26276805 8.73 ENSDART00000089749
adipoqa
adiponectin, C1Q and collagen domain containing, a
chr19_+_46113828 8.72 ENSDART00000159331
ENSDART00000161826
rbm24a
RNA binding motif protein 24a
chr21_-_35419486 8.70 ENSDART00000138529
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr21_+_28749720 8.69 ENSDART00000145178
zgc:100829
zgc:100829
chr9_-_23944470 8.42 ENSDART00000138754
col6a3
collagen, type VI, alpha 3
chr14_-_17563773 8.32 ENSDART00000082667
fgfrl1a
fibroblast growth factor receptor like 1a
chr14_+_6159356 8.31 ENSDART00000157730
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr7_+_20467549 8.27 ENSDART00000173724
si:dkey-33c9.8
si:dkey-33c9.8
chr5_-_31904562 8.23 ENSDART00000140640
coro1cb
coronin, actin binding protein, 1Cb
chr6_-_7052408 8.23 ENSDART00000150033
ENSDART00000149232
bin1b
bridging integrator 1b
chr9_-_49531762 8.20 ENSDART00000121875
xirp2b
xin actin binding repeat containing 2b
chr1_+_50293938 8.19 ENSDART00000084184
aimp1
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
chr7_-_40578733 8.09 ENSDART00000173926
ENSDART00000010035
dnajb6b
DnaJ (Hsp40) homolog, subfamily B, member 6b
chr6_+_40629066 7.99 ENSDART00000103757
slc6a11a
solute carrier family 6 (neurotransmitter transporter), member 11a
chr3_-_32169754 7.93 ENSDART00000179010
tnnt1
troponin T type 1 (skeletal, slow)
chr6_-_35401282 7.90 ENSDART00000127612
rgs5a
regulator of G protein signaling 5a
chr7_+_65586624 7.79 ENSDART00000184344
mical2a
microtubule associated monooxygenase, calponin and LIM domain containing 2a
chr7_-_41858513 7.69 ENSDART00000109918
mylk3
myosin light chain kinase 3
chr8_+_45294767 7.68 ENSDART00000191527
ubap2b
ubiquitin associated protein 2b
chr8_+_4337312 7.55 ENSDART00000182228
myl2b
myosin, light chain 2b, regulatory, cardiac, slow
chr14_-_9281232 7.52 ENSDART00000054693
asb12b
ankyrin repeat and SOCS box-containing 12b
chr17_+_23462972 7.49 ENSDART00000112959
ENSDART00000192168
ankrd1a
ankyrin repeat domain 1a (cardiac muscle)
chr25_-_6557854 7.34 ENSDART00000181740
cspg4
chondroitin sulfate proteoglycan 4
chr16_-_42894628 7.32 ENSDART00000045600
hfe2
hemochromatosis type 2
chr13_-_1349922 7.25 ENSDART00000140970
si:ch73-52p7.1
si:ch73-52p7.1
chr8_+_44926946 7.19 ENSDART00000098567
zgc:154046
zgc:154046
chr18_+_23218980 7.18 ENSDART00000185014
mef2aa
myocyte enhancer factor 2aa
chr6_+_49028874 7.14 ENSDART00000175254
slc16a1a
solute carrier family 16 (monocarboxylate transporter), member 1a
chr2_-_24289641 7.11 ENSDART00000128784
ENSDART00000123565
ENSDART00000141922
ENSDART00000184550
ENSDART00000191469
myh7l
myosin heavy chain 7-like
chr5_+_15203421 7.06 ENSDART00000040826
tbx1
T-box 1
chr11_+_31285127 7.01 ENSDART00000160154
si:dkey-238i5.2
si:dkey-238i5.2
chr4_-_20181964 6.99 ENSDART00000022539
fgl2a
fibrinogen-like 2a
chr12_-_25380028 6.94 ENSDART00000142674
zfp36l2
zinc finger protein 36, C3H type-like 2
chr6_-_39051319 6.94 ENSDART00000155093
tns2b
tensin 2b
chr16_-_24642814 6.90 ENSDART00000153987
ENSDART00000154319
fxyd6l
FXYD domain containing ion transport regulator 6 like
chr21_+_10866421 6.80 ENSDART00000137858
alpk2
alpha-kinase 2
chr18_+_23249519 6.79 ENSDART00000005740
ENSDART00000147446
ENSDART00000124818
mef2aa
myocyte enhancer factor 2aa
chr24_-_41679356 6.79 ENSDART00000046821
lrrc30a
leucine rich repeat containing 30a
chr20_-_49681850 6.73 ENSDART00000025926
col12a1b
collagen, type XII, alpha 1b
chr22_+_11756040 6.70 ENSDART00000105808
krt97
keratin 97
chr2_+_50999477 6.66 ENSDART00000190111
eef1da
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr4_-_78026285 6.64 ENSDART00000168273
CCT2
chaperonin containing TCP1 subunit 2
chr4_-_4834347 6.63 ENSDART00000141803
coa6
cytochrome c oxidase assembly factor 6
chr10_+_24468922 6.58 ENSDART00000008248
ENSDART00000183510
slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr11_-_18705303 6.57 ENSDART00000059732
id1
inhibitor of DNA binding 1
chr3_-_26122353 6.56 ENSDART00000111042
ENSDART00000161427
hsp70.2
heat shock cognate 70-kd protein, tandem duplicate 2
chr23_-_9925568 6.51 ENSDART00000081268
si:ch211-220i18.4
si:ch211-220i18.4
chr14_-_29905962 6.44 ENSDART00000142605
sorbs2b
sorbin and SH3 domain containing 2b
chr5_-_34997630 6.35 ENSDART00000170684
btf3
basic transcription factor 3
chr19_+_24488403 6.17 ENSDART00000052421
txnipa
thioredoxin interacting protein a
chr20_-_54208344 6.11 ENSDART00000169386
faua
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed a
chr3_-_31783737 6.08 ENSDART00000090809
kcnh6a
potassium voltage-gated channel, subfamily H (eag-related), member 6a
chr7_+_55112922 6.04 ENSDART00000073549
snai3
snail family zinc finger 3
chr6_-_10912424 6.02 ENSDART00000036456
cycsb
cytochrome c, somatic b
chr10_-_13178853 5.97 ENSDART00000163740
ENSDART00000166327
ENSDART00000160265
ENSDART00000164299
musk
muscle, skeletal, receptor tyrosine kinase
chr3_+_13559199 5.93 ENSDART00000166547
si:ch73-106n3.1
si:ch73-106n3.1
chr24_+_19518570 5.82 ENSDART00000056081
sulf1
sulfatase 1
chr11_+_21050326 5.73 ENSDART00000065984
zgc:113307
zgc:113307
chr1_-_51734524 5.70 ENSDART00000109640
ENSDART00000122628
junba
JunB proto-oncogene, AP-1 transcription factor subunit a
chr13_-_37615029 5.59 ENSDART00000111199
si:dkey-188i13.6
si:dkey-188i13.6
chr4_+_8670662 5.55 ENSDART00000168768
adipor2
adiponectin receptor 2
chr14_-_17659420 5.55 ENSDART00000165566
si:ch211-159i8.4
si:ch211-159i8.4
chr3_+_2669813 5.52 ENSDART00000014205
CR388047.1

chr19_-_15281996 5.52 ENSDART00000103784
edn2
endothelin 2
chr17_+_132555 5.48 ENSDART00000158159
zgc:77287
zgc:77287
chr3_-_22242868 5.47 ENSDART00000184511
ENSDART00000191558
ENSDART00000179846
myl4
myosin, light chain 4, alkali; atrial, embryonic
chr17_-_45370200 5.46 ENSDART00000186208
znf106a
zinc finger protein 106a
chr16_+_35905031 5.45 ENSDART00000162411
sh3d21
SH3 domain containing 21
chr19_-_7450796 5.45 ENSDART00000104750
mllt11
MLLT11, transcription factor 7 cofactor
chr1_+_27690 5.41 ENSDART00000162928
eed
embryonic ectoderm development
chr8_+_4798158 5.39 ENSDART00000031650
hsp70l
heat shock cognate 70-kd protein, like
chr6_-_48082525 5.39 ENSDART00000192049
slc2a1b
solute carrier family 2 (facilitated glucose transporter), member 1b
chr7_+_22718251 5.39 ENSDART00000027718
ENSDART00000143341
fxr2
fragile X mental retardation, autosomal homolog 2
chr23_+_19790962 5.39 ENSDART00000142228
flna
filamin A, alpha (actin binding protein 280)
chr1_+_55002583 5.37 ENSDART00000037250
si:ch211-196h16.12
si:ch211-196h16.12
chr21_-_217589 5.36 ENSDART00000185017
CZQB01146713.1

chr11_+_27364338 5.34 ENSDART00000186759
fbln2
fibulin 2
chr2_-_23778180 5.34 ENSDART00000136782
si:dkey-24c2.7
si:dkey-24c2.7
chr12_+_28749189 5.30 ENSDART00000013980
tbx21
T-box 21
chr10_-_8294965 5.28 ENSDART00000167380
plpp1a
phospholipid phosphatase 1a
chr24_+_19518303 5.26 ENSDART00000027022
ENSDART00000056080
sulf1
sulfatase 1
chr2_+_50999675 5.26 ENSDART00000158064
ENSDART00000165746
ENSDART00000163917
ENSDART00000172038
ENSDART00000169048
ENSDART00000164775
eef1da
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr5_+_6670945 5.21 ENSDART00000185686
pxna
paxillin a
chr10_-_8295294 5.12 ENSDART00000075412
ENSDART00000163803
plpp1a
phospholipid phosphatase 1a
chr7_+_49715750 5.11 ENSDART00000019446
ascl1b
achaete-scute family bHLH transcription factor 1b
chr22_+_18477934 5.10 ENSDART00000132684
cilp2
cartilage intermediate layer protein 2
chr3_-_31784082 5.07 ENSDART00000134201
kcnh6a
potassium voltage-gated channel, subfamily H (eag-related), member 6a
chr17_+_53311243 5.04 ENSDART00000160241
ENSDART00000160009
ENSDART00000162239
asb2b
ankyrin repeat and SOCS box containing 2b
chr25_-_3549321 5.04 ENSDART00000181214
ENSDART00000160600
hdhd5
haloacid dehalogenase like hydrolase domain containing 5
chr15_-_4528326 4.98 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
tfdp2
transcription factor Dp-2
chr5_+_64900223 4.91 ENSDART00000191677
ptgs1
prostaglandin-endoperoxide synthase 1
chr23_+_43950674 4.91 ENSDART00000167813
corin
corin, serine peptidase
chr4_-_18211 4.87 ENSDART00000171737
ptpn12
protein tyrosine phosphatase, non-receptor type 12
chr9_-_105135 4.86 ENSDART00000180126
FQ377903.3

chr21_-_7265219 4.85 ENSDART00000158852
egfl7
EGF-like-domain, multiple 7
chr3_-_19368435 4.81 ENSDART00000132987
s1pr5a
sphingosine-1-phosphate receptor 5a
chr17_-_14876758 4.80 ENSDART00000155857
nid2a
nidogen 2a (osteonidogen)
chr16_-_25233515 4.80 ENSDART00000058943
zgc:110182
zgc:110182
chr5_+_23630384 4.79 ENSDART00000013745
cx39.9
connexin 39.9
chr14_-_32884138 4.72 ENSDART00000105726
slc25a5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr5_+_37785152 4.69 ENSDART00000053511
ENSDART00000189812
myo1ca
myosin Ic, paralog a
chr7_+_13756374 4.69 ENSDART00000180808
rasl12
RAS-like, family 12
chr5_-_52569014 4.68 ENSDART00000165616
mamdc2a
MAM domain containing 2a
chr1_-_11075403 4.68 ENSDART00000102903
ENSDART00000170290
dmd
dystrophin
chr5_-_48307804 4.65 ENSDART00000182831
ENSDART00000186920
ENSDART00000183585
mef2cb
myocyte enhancer factor 2cb
chr3_-_34561624 4.64 ENSDART00000129313
sept9a
septin 9a
chr17_+_15041647 4.60 ENSDART00000108999
samd4a
sterile alpha motif domain containing 4A
chr23_-_18057553 4.53 ENSDART00000173102
ENSDART00000058742
zgc:92287
zgc:92287
chr9_+_22764235 4.52 ENSDART00000090875
tnfaip6
tumor necrosis factor, alpha-induced protein 6
chr7_+_73690366 4.47 ENSDART00000191494
ENSDART00000123429
ENSDART00000173403
si:dkey-46i9.6
si:dkey-46i9.6
chr6_+_43234213 4.47 ENSDART00000112474
arl6ip5a
ADP-ribosylation factor-like 6 interacting protein 5a
chr10_+_26871751 4.42 ENSDART00000089205
ehbp1l1b
EH domain binding protein 1-like 1b
chr14_+_6159162 4.42 ENSDART00000128638
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr19_+_31044487 4.41 ENSDART00000143494
ankmy2b
ankyrin repeat and MYND domain containing 2b
chr12_+_18768021 4.35 ENSDART00000153111
mkl1b
megakaryoblastic leukemia (translocation) 1b
chr22_+_11775269 4.30 ENSDART00000140272
krt96
keratin 96
chr11_+_21053488 4.30 ENSDART00000189860
zgc:113307
zgc:113307

Network of associatons between targets according to the STRING database.

First level regulatory network of myod1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
13.2 39.5 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
12.3 61.4 GO:0003210 cardiac atrium formation(GO:0003210)
6.5 19.5 GO:0065001 specification of axis polarity(GO:0065001)
6.0 18.0 GO:0043388 positive regulation of DNA binding(GO:0043388)
5.5 43.7 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
5.4 21.8 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
3.8 22.8 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
3.6 39.6 GO:0006735 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
3.5 31.5 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
3.4 44.8 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
2.8 11.1 GO:0060306 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
2.8 16.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
2.6 29.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
2.6 36.9 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
2.5 17.2 GO:0033292 T-tubule organization(GO:0033292)
2.5 19.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
2.4 7.1 GO:0043282 regulation of organ formation(GO:0003156) pharyngeal muscle development(GO:0043282)
1.9 14.9 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
1.8 16.6 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
1.8 12.7 GO:0034389 lipid particle organization(GO:0034389)
1.8 9.1 GO:0097272 ammonia homeostasis(GO:0097272)
1.6 13.1 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
1.6 8.0 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
1.5 13.6 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
1.5 13.5 GO:0007525 somatic muscle development(GO:0007525)
1.5 19.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.4 7.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
1.4 4.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
1.4 5.5 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
1.3 3.9 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
1.3 7.7 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
1.2 22.4 GO:0051764 actin crosslink formation(GO:0051764)
1.2 4.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.2 9.7 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
1.2 2.4 GO:1903779 regulation of cardiac conduction(GO:1903779)
1.2 4.7 GO:0015859 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
1.2 13.8 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
1.1 7.9 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
1.1 26.0 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
1.1 5.4 GO:0090199 regulation of mitochondrial membrane potential(GO:0051881) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
1.0 13.9 GO:0055003 cardiac myofibril assembly(GO:0055003)
1.0 1.0 GO:0001659 temperature homeostasis(GO:0001659)
0.9 36.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.9 3.5 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.8 2.5 GO:0048496 maintenance of organ identity(GO:0048496)
0.8 4.0 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.8 19.8 GO:0006094 gluconeogenesis(GO:0006094)
0.8 3.8 GO:0051103 DNA ligation(GO:0006266) immunoglobulin V(D)J recombination(GO:0033152) DNA ligation involved in DNA repair(GO:0051103)
0.7 5.2 GO:0061055 myotome development(GO:0061055)
0.7 10.9 GO:0042026 protein refolding(GO:0042026)
0.7 8.6 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.7 8.3 GO:0021592 fourth ventricle development(GO:0021592)
0.7 2.7 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.7 4.1 GO:0003334 keratinocyte development(GO:0003334)
0.7 3.4 GO:1903146 regulation of mitophagy(GO:1903146)
0.7 1.3 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.6 2.5 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.6 3.0 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.6 4.2 GO:0040016 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) embryonic cleavage(GO:0040016)
0.6 2.9 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.6 1.7 GO:0000212 meiotic spindle organization(GO:0000212)
0.6 3.9 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.5 5.6 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.5 12.8 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.5 1.4 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.5 8.5 GO:0033077 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.5 1.9 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.5 9.9 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.5 49.2 GO:0048738 cardiac muscle tissue development(GO:0048738)
0.5 4.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.4 2.2 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.4 11.3 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.4 22.2 GO:0000187 activation of MAPK activity(GO:0000187)
0.4 16.8 GO:0030199 collagen fibril organization(GO:0030199)
0.4 10.7 GO:0010508 positive regulation of autophagy(GO:0010508)
0.4 1.3 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.4 24.8 GO:0051693 actin filament capping(GO:0051693)
0.4 1.2 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.4 6.7 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.4 1.9 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.4 2.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.3 1.7 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.3 2.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 2.7 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.3 7.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 3.3 GO:0050975 sensory perception of touch(GO:0050975)
0.3 7.9 GO:0060048 cardiac muscle contraction(GO:0060048)
0.3 8.9 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.3 8.1 GO:0061386 closure of optic fissure(GO:0061386)
0.3 1.4 GO:0016037 light absorption(GO:0016037)
0.3 0.9 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.3 5.7 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.3 1.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 2.0 GO:0060017 parathyroid gland development(GO:0060017)
0.3 6.4 GO:0015701 bicarbonate transport(GO:0015701)
0.3 4.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.3 2.2 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.3 6.9 GO:0007286 spermatid development(GO:0007286)
0.3 0.8 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 0.5 GO:0048660 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.3 2.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.3 3.0 GO:0001840 neural plate development(GO:0001840)
0.2 1.0 GO:0010259 multicellular organism aging(GO:0010259)
0.2 2.0 GO:0061709 reticulophagy(GO:0061709)
0.2 0.7 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.2 0.7 GO:0001113 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.2 3.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.2 2.4 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 3.5 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.2 7.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 3.9 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 4.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 4.0 GO:0002574 thrombocyte differentiation(GO:0002574)
0.2 15.4 GO:0030239 myofibril assembly(GO:0030239)
0.2 0.6 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.2 0.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.2 1.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 2.0 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.2 1.4 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.2 1.2 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.2 3.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 11.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.2 3.7 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.2 0.5 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 1.8 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.2 3.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 1.8 GO:0060612 adipose tissue development(GO:0060612)
0.2 1.1 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.2 2.1 GO:0033198 response to ATP(GO:0033198)
0.2 3.3 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 0.9 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.2 5.5 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.2 1.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2 2.0 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.2 3.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 1.6 GO:0061157 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.2 6.8 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2 5.5 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.2 1.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.0 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.1 16.2 GO:0060047 heart contraction(GO:0060047)
0.1 1.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 1.2 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) ventral spinal cord interneuron fate commitment(GO:0060579)
0.1 3.4 GO:0046514 ceramide catabolic process(GO:0046514)
0.1 2.3 GO:0051899 membrane depolarization(GO:0051899)
0.1 3.3 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.1 8.7 GO:0006414 translational elongation(GO:0006414)
0.1 2.0 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.1 1.0 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.1 3.4 GO:0010634 positive regulation of epithelial cell migration(GO:0010634)
0.1 10.4 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 0.8 GO:0032447 protein urmylation(GO:0032447)
0.1 0.6 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 4.3 GO:0051051 negative regulation of transport(GO:0051051)
0.1 9.7 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 8.7 GO:0007416 synapse assembly(GO:0007416)
0.1 5.4 GO:0001570 vasculogenesis(GO:0001570)
0.1 10.2 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.1 2.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 4.4 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.1 1.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.4 GO:0051122 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 4.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 7.8 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 3.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 0.8 GO:1900186 optomotor response(GO:0071632) caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 4.6 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.1 7.7 GO:0031101 fin regeneration(GO:0031101)
0.1 0.7 GO:0006501 C-terminal protein lipidation(GO:0006501) lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) single-organism membrane invagination(GO:1902534)
0.1 0.7 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 3.0 GO:0016525 negative regulation of angiogenesis(GO:0016525) negative regulation of vasculature development(GO:1901343) negative regulation of blood vessel morphogenesis(GO:2000181)
0.1 0.6 GO:0032728 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.1 0.8 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 1.5 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 2.4 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 1.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 5.9 GO:0072676 lymphocyte migration(GO:0072676)
0.1 0.7 GO:0030104 water homeostasis(GO:0030104)
0.1 1.2 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058) regulation of ERBB signaling pathway(GO:1901184)
0.1 0.6 GO:0008406 gonad development(GO:0008406)
0.1 1.2 GO:0045471 response to ethanol(GO:0045471)
0.1 5.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 1.0 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.5 GO:0034661 ncRNA catabolic process(GO:0034661)
0.1 0.9 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.0 GO:0042698 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.1 7.3 GO:0032835 glomerulus development(GO:0032835)
0.1 0.3 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 3.2 GO:0006090 pyruvate metabolic process(GO:0006090)
0.1 3.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 2.5 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1 1.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 4.8 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.1 3.5 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 0.5 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 1.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.1 1.7 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 2.4 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 1.0 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.7 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.9 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.3 GO:0042311 vasodilation(GO:0042311)
0.1 2.1 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 2.4 GO:0007266 Rho protein signal transduction(GO:0007266)
0.1 2.0 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.6 GO:0019935 cyclic-nucleotide-mediated signaling(GO:0019935)
0.1 1.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.4 GO:0008272 sulfate transport(GO:0008272)
0.1 0.6 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 1.2 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.9 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 5.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 4.4 GO:0006342 chromatin silencing(GO:0006342)
0.1 2.8 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of chemotaxis(GO:0050922) negative regulation of axon guidance(GO:1902668)
0.1 2.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 33.7 GO:0016567 protein ubiquitination(GO:0016567)
0.1 1.3 GO:0006298 mismatch repair(GO:0006298)
0.1 0.9 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.1 4.9 GO:0046474 glycerophospholipid biosynthetic process(GO:0046474)
0.0 0.7 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 1.7 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0002363 CD4-positive, alpha-beta T cell differentiation involved in immune response(GO:0002294) T-helper cell lineage commitment(GO:0002295) T cell lineage commitment(GO:0002360) alpha-beta T cell lineage commitment(GO:0002363) T-helper cell differentiation(GO:0042093) CD4-positive, alpha-beta T cell differentiation(GO:0043367) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540)
0.0 1.7 GO:0007050 cell cycle arrest(GO:0007050)
0.0 8.9 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 3.5 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 1.8 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.6 GO:0030534 adult behavior(GO:0030534)
0.0 1.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.2 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.5 GO:0006265 DNA topological change(GO:0006265)
0.0 1.5 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 2.7 GO:0008544 epidermis development(GO:0008544)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.8 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.5 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.3 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.9 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 2.2 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 1.8 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.5 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 2.9 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 1.0 GO:0051607 defense response to virus(GO:0051607)
0.0 0.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 1.0 GO:0007283 spermatogenesis(GO:0007283)
0.0 1.7 GO:0050684 regulation of mRNA processing(GO:0050684)
0.0 0.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 111.6 GO:0031672 A band(GO:0031672)
3.6 39.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
2.3 11.4 GO:0008091 spectrin(GO:0008091)
1.9 39.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
1.7 11.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.6 13.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
1.6 144.2 GO:0030018 Z disc(GO:0030018)
1.4 59.8 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
1.4 59.0 GO:0005861 troponin complex(GO:0005861)
1.3 5.4 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
1.3 3.8 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
1.2 4.7 GO:0060171 stereocilium membrane(GO:0060171)
1.1 12.0 GO:0008180 COP9 signalosome(GO:0008180)
1.1 6.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.8 8.9 GO:0061617 MICOS complex(GO:0061617)
0.7 12.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.7 2.0 GO:1990879 CST complex(GO:1990879)
0.6 13.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.5 2.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.5 3.0 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.5 2.0 GO:0097519 DNA recombinase complex(GO:0097519)
0.5 4.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 3.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.4 5.1 GO:0002102 podosome(GO:0002102)
0.4 2.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.3 1.7 GO:1990071 TRAPPII protein complex(GO:1990071)
0.3 3.7 GO:0045095 keratin filament(GO:0045095)
0.3 40.7 GO:0030055 cell-substrate junction(GO:0030055)
0.3 0.9 GO:0033391 chromatoid body(GO:0033391)
0.3 7.5 GO:0005839 proteasome core complex(GO:0005839)
0.2 0.7 GO:0033268 node of Ranvier(GO:0033268)
0.2 7.0 GO:0031941 filamentous actin(GO:0031941)
0.2 1.2 GO:0070062 extracellular exosome(GO:0070062)
0.2 9.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 15.3 GO:0005882 intermediate filament(GO:0005882)
0.2 2.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 17.5 GO:0005581 collagen trimer(GO:0005581)
0.2 0.9 GO:0070390 transcription export complex 2(GO:0070390)
0.2 4.3 GO:0031594 neuromuscular junction(GO:0031594)
0.2 1.0 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.1 3.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.7 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 1.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 3.4 GO:0000795 synaptonemal complex(GO:0000795)
0.1 2.0 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 1.3 GO:0032300 mismatch repair complex(GO:0032300)
0.1 1.0 GO:0097225 sperm midpiece(GO:0097225)
0.1 11.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.6 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 4.2 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 2.1 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 1.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 5.6 GO:0005657 replication fork(GO:0005657)
0.1 34.7 GO:0005667 transcription factor complex(GO:0005667)
0.1 3.9 GO:0031012 extracellular matrix(GO:0031012)
0.1 5.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 2.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 1.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.1 3.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 25.5 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 7.7 GO:0005795 Golgi stack(GO:0005795)
0.1 0.3 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 8.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 2.4 GO:0005876 spindle microtubule(GO:0005876)
0.1 5.0 GO:0005604 basement membrane(GO:0005604)
0.1 0.9 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 3.9 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 0.7 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 1.8 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 6.0 GO:0000786 nucleosome(GO:0000786)
0.0 5.5 GO:0005840 ribosome(GO:0005840)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 14.4 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 3.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 4.1 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.8 GO:0071565 nBAF complex(GO:0071565)
0.0 1.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.7 GO:0045180 basal part of cell(GO:0045178) basal cortex(GO:0045180)
0.0 3.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.4 GO:0043195 terminal bouton(GO:0043195)
0.0 1.8 GO:0005814 centriole(GO:0005814)
0.0 1.9 GO:0005871 kinesin complex(GO:0005871)
0.0 3.9 GO:0005635 nuclear envelope(GO:0005635)
0.0 41.1 GO:0005576 extracellular region(GO:0005576)
0.0 3.6 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0030286 dynein complex(GO:0030286)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.9 31.5 GO:0071253 connexin binding(GO:0071253)
7.5 52.5 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
5.6 61.4 GO:0032036 myosin heavy chain binding(GO:0032036)
3.9 38.5 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
3.6 39.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
3.5 10.4 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
3.3 49.1 GO:0051879 Hsp90 protein binding(GO:0051879)
2.9 8.7 GO:1990715 mRNA CDS binding(GO:1990715) sequence-specific mRNA binding(GO:1990825)
2.8 16.5 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
2.7 10.8 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
2.4 19.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.8 7.2 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
1.7 12.1 GO:0004126 cytidine deaminase activity(GO:0004126)
1.6 13.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
1.4 19.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.4 5.5 GO:0031708 endothelin B receptor binding(GO:0031708)
1.4 8.2 GO:0048156 tau protein binding(GO:0048156)
1.4 15.0 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
1.3 16.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.2 13.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
1.2 4.9 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
1.2 12.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.2 4.7 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
1.2 15.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
1.1 26.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
1.1 23.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
1.1 5.6 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
1.1 9.7 GO:0004359 glutaminase activity(GO:0004359)
0.9 4.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.9 3.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.9 10.0 GO:0005523 tropomyosin binding(GO:0005523)
0.9 14.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.9 3.5 GO:1990931 RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.8 2.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.8 3.2 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.8 5.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.8 29.2 GO:0005518 collagen binding(GO:0005518)
0.7 10.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.7 2.7 GO:0008169 C-methyltransferase activity(GO:0008169)
0.6 4.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.6 7.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.6 4.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.6 2.9 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.5 2.1 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.5 2.5 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.5 2.0 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.5 1.4 GO:0009041 uridylate kinase activity(GO:0009041)
0.5 1.4 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.4 21.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.4 7.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.4 8.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.4 2.3 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.4 4.9 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.4 3.7 GO:0070700 BMP receptor binding(GO:0070700)
0.4 9.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.3 2.0 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.3 18.5 GO:0044325 ion channel binding(GO:0044325)
0.3 2.6 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.3 1.9 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.3 1.9 GO:0017040 ceramidase activity(GO:0017040)
0.3 7.8 GO:0005112 Notch binding(GO:0005112)
0.3 4.3 GO:0030506 ankyrin binding(GO:0030506)
0.3 3.9 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.3 4.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.3 3.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 0.9 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.3 11.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 1.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.3 11.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 1.8 GO:0004974 leukotriene receptor activity(GO:0004974)
0.3 4.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.2 89.1 GO:0051015 actin filament binding(GO:0051015)
0.2 4.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 4.3 GO:0005080 protein kinase C binding(GO:0005080)
0.2 1.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 5.0 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 3.9 GO:0032190 acrosin binding(GO:0032190)
0.2 1.5 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.2 1.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 3.9 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.2 0.8 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.2 4.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 6.2 GO:0019003 GDP binding(GO:0019003)
0.2 16.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 2.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 49.5 GO:0003779 actin binding(GO:0003779)
0.2 3.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 1.0 GO:0070330 aromatase activity(GO:0070330)
0.2 1.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 3.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 0.6 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 1.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 1.5 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 10.2 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1 0.7 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 1.5 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 1.7 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 1.8 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 4.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 3.1 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 1.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 6.2 GO:0031491 nucleosome binding(GO:0031491)
0.1 5.5 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.4 GO:0048185 activin binding(GO:0048185)
0.1 1.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 48.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 3.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.6 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.6 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 7.9 GO:0003823 antigen binding(GO:0003823)
0.1 0.8 GO:0031386 protein tag(GO:0031386)
0.1 2.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 18.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 2.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.7 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 1.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 5.8 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 5.9 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 0.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 41.8 GO:0046983 protein dimerization activity(GO:0046983)
0.1 2.0 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 1.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.9 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 2.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 3.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 12.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.6 GO:0009055 electron carrier activity(GO:0009055)
0.1 2.4 GO:0005109 frizzled binding(GO:0005109)
0.1 1.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.7 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 2.1 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.1 1.2 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 1.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.6 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 1.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 17.4 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.0 1.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.8 GO:0051540 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 5.1 GO:0005125 cytokine activity(GO:0005125)
0.0 2.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.7 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 1.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 1.2 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 1.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 2.7 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 3.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 12.1 GO:0005525 GTP binding(GO:0005525)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0 0.7 GO:0046332 SMAD binding(GO:0046332)
0.0 13.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 1.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 29.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.7 23.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.6 13.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.5 7.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.5 18.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.4 10.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.4 3.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.4 2.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 6.6 PID IL3 PATHWAY IL3-mediated signaling events
0.3 13.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.3 17.8 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.3 5.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 8.7 PID ENDOTHELIN PATHWAY Endothelins
0.2 4.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 1.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 3.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 2.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.2 3.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.2 4.8 PID BMP PATHWAY BMP receptor signaling
0.2 6.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 2.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 3.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 0.9 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 9.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.8 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 49.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
1.6 12.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
1.4 18.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.9 2.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.8 12.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.6 3.8 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.5 13.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.5 9.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.5 14.8 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.4 1.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.3 11.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.3 6.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.3 3.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 1.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 2.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 2.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 2.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 5.9 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 2.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 8.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 4.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 1.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 2.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 4.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 4.7 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 2.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 6.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 3.7 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.1 1.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.6 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 2.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 6.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 0.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 5.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 3.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.7 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.1 1.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 4.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 2.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 2.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.9 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.0 0.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.8 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.6 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor