Project
PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish
Navigation
Downloads
Results for myod1
Z-value: 2.16
Motif logo
Transcription factors associated with myod1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| myod1 | dr11_v1_chr25_-_31423493_31423493 | 0.78 | 4.2e-20 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_-_32817274 Show fit | 47.40 |
ENSDART00000142582
|
myosin light chain, phosphorylatable, fast skeletal muscle a |
|
| chr8_-_1051438 Show fit | 35.50 |
ENSDART00000067093
ENSDART00000170737 |
SET and MYND domain containing 1b |
|
| chr6_-_42003780 Show fit | 31.49 |
ENSDART00000032527
|
caveolin 3 |
|
| chr3_+_32526263 Show fit | 29.90 |
ENSDART00000150897
|
si:ch73-367p23.2 |
|
| chr2_+_55982940 Show fit | 28.12 |
ENSDART00000097753
ENSDART00000097751 |
nicotinamide riboside kinase 2 |
|
| chr3_+_32526799 Show fit | 26.92 |
ENSDART00000185755
|
si:ch73-367p23.2 |
|
| chr22_-_14128716 Show fit | 26.37 |
ENSDART00000140323
|
si:ch211-246m6.4 |
|
| chr21_+_27382893 Show fit | 25.57 |
ENSDART00000005682
|
actinin alpha 3a |
|
| chr2_+_55982300 Show fit | 24.42 |
ENSDART00000183903
|
nicotinamide riboside kinase 2 |
|
| chr7_+_31891110 Show fit | 23.10 |
ENSDART00000173883
|
myosin binding protein C, cardiac |
Network of associatons between targets according to the STRING database.
First level regulatory network of myod1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 12.3 | 61.4 | GO:0003210 | cardiac atrium formation(GO:0003210) |
| 0.5 | 49.2 | GO:0048738 | cardiac muscle tissue development(GO:0048738) |
| 3.4 | 44.8 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
| 5.5 | 43.7 | GO:0003209 | cardiac atrium morphogenesis(GO:0003209) |
| 3.6 | 39.6 | GO:0006735 | glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 13.2 | 39.5 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
| 2.6 | 36.9 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.9 | 36.1 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
| 0.1 | 33.7 | GO:0016567 | protein ubiquitination(GO:0016567) |
| 3.5 | 31.5 | GO:0046716 | muscle cell cellular homeostasis(GO:0046716) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 144.2 | GO:0030018 | Z disc(GO:0030018) |
| 3.6 | 111.6 | GO:0031672 | A band(GO:0031672) |
| 1.4 | 59.8 | GO:0044853 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
| 1.4 | 59.0 | GO:0005861 | troponin complex(GO:0005861) |
| 0.0 | 41.1 | GO:0005576 | extracellular region(GO:0005576) |
| 0.3 | 40.7 | GO:0030055 | cell-substrate junction(GO:0030055) |
| 3.6 | 39.6 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 1.9 | 39.0 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 34.7 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.1 | 25.5 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 89.1 | GO:0051015 | actin filament binding(GO:0051015) |
| 5.6 | 61.4 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 7.5 | 52.5 | GO:0050262 | ribosylnicotinamide kinase activity(GO:0050262) |
| 0.2 | 49.5 | GO:0003779 | actin binding(GO:0003779) |
| 3.3 | 49.1 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.1 | 48.4 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.1 | 41.8 | GO:0046983 | protein dimerization activity(GO:0046983) |
| 3.6 | 39.6 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 3.9 | 38.5 | GO:0051373 | telethonin binding(GO:0031433) FATZ binding(GO:0051373) |
| 7.9 | 31.5 | GO:0071253 | connexin binding(GO:0071253) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 29.1 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.7 | 23.4 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.5 | 18.5 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.3 | 17.8 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.6 | 13.6 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.3 | 13.4 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.4 | 10.5 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 9.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.2 | 8.7 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.5 | 7.1 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 49.7 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 1.4 | 18.0 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.5 | 14.8 | REACTOME PIP3 ACTIVATES AKT SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.5 | 13.1 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 1.6 | 12.8 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.8 | 12.1 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.3 | 11.8 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.5 | 9.1 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.2 | 8.4 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.3 | 6.6 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |