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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for myog

Z-value: 1.31

Motif logo

Transcription factors associated with myog

Gene Symbol Gene ID Gene Info
ENSDARG00000009438 myogenin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
myogdr11_v1_chr11_-_22599584_225995840.595.3e-10Click!

Activity profile of myog motif

Sorted Z-values of myog motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_61203203 29.67 ENSDART00000171787
parvalbumin 1
chr21_+_27382893 24.80 ENSDART00000005682
actinin alpha 3a
chr7_+_29951997 22.39 ENSDART00000173453
alpha-tropomyosin
chr20_-_27325258 18.30 ENSDART00000152917
ankyrin repeat and SOCS box containing 2a, tandem duplicate 1
chr18_+_5549672 14.10 ENSDART00000184970
nicotinamide nucleotide transhydrogenase 2
chr2_+_42191592 14.06 ENSDART00000144716
caveolae associated protein 4a
chr23_-_45405968 13.89 ENSDART00000149462
zgc:101853
chr7_+_39444843 13.67 ENSDART00000143999
ENSDART00000173554
ENSDART00000173698
ENSDART00000173754
ENSDART00000144075
ENSDART00000138192
ENSDART00000145457
ENSDART00000141750
ENSDART00000103056
ENSDART00000142946
ENSDART00000173748
troponin T type 3b (skeletal, fast)
chr3_+_26145013 11.88 ENSDART00000162546
ENSDART00000129561
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr24_+_20575259 11.39 ENSDART00000010488
kelch-like family member 40b
chr22_+_20720808 11.29 ENSDART00000171321
si:dkey-211f22.5
chr6_-_32703317 11.22 ENSDART00000064833
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa
chr8_-_1051438 10.34 ENSDART00000067093
ENSDART00000170737
SET and MYND domain containing 1b
chr2_-_21335131 10.33 ENSDART00000057022
kelch-like family member 40a
chr11_-_5865744 9.63 ENSDART00000104360
guanidinoacetate N-methyltransferase
chr6_-_21492752 9.36 ENSDART00000006843
ENSDART00000171479
calcium channel, voltage-dependent, gamma subunit 1a
chr16_-_14074594 9.30 ENSDART00000090234
tripartite motif containing 109
chr6_-_42003780 9.29 ENSDART00000032527
caveolin 3
chr9_-_100579 9.13 ENSDART00000006099
LIM and senescent cell antigen-like domains 2
chr19_-_10425140 8.95 ENSDART00000145319
si:ch211-171h4.3
chr11_+_7158723 8.92 ENSDART00000035560
transmembrane protein 38A
chr13_-_31622195 8.65 ENSDART00000057432
SIX homeobox 1a
chr18_+_5454341 8.49 ENSDART00000192649
DTW domain containing 1
chr24_-_33703504 7.99 ENSDART00000079292
caveolae associated protein 4b
chr3_+_57991074 7.90 ENSDART00000076077
myeloid-associated differentiation marker-like 2
chr19_+_14109348 7.39 ENSDART00000159015
zgc:175136
chr3_+_26144765 7.34 ENSDART00000146267
ENSDART00000043932
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr17_+_27434626 7.30 ENSDART00000052446
vestigial-like family member 2b
chr9_-_48281941 6.82 ENSDART00000099787
kelch-like family member 41a
chr16_-_42894628 6.81 ENSDART00000045600
hemochromatosis type 2
chr14_-_9281232 6.70 ENSDART00000054693
ankyrin repeat and SOCS box-containing 12b
chr20_-_36887516 6.64 ENSDART00000076313
taxilin beta a
chr10_-_44560165 6.59 ENSDART00000181217
ENSDART00000076084
nucleophosmin/nucleoplasmin, 2b
chr23_+_44614056 6.56 ENSDART00000188379
enolase 3, (beta, muscle)
chr17_-_722218 6.46 ENSDART00000160385
solute carrier family 25 member 29
chr18_+_23218980 6.42 ENSDART00000185014
myocyte enhancer factor 2aa
chr23_-_18057553 6.28 ENSDART00000173102
ENSDART00000058742
zgc:92287
chr9_-_43071519 6.27 ENSDART00000109099
titin, tandem duplicate 2
chr24_+_39108243 6.20 ENSDART00000156353
MSS51 mitochondrial translational activator
chr17_-_14815557 6.15 ENSDART00000154473
nidogen 2a (osteonidogen)
chr6_-_32093830 5.83 ENSDART00000017695
forkhead box D3
chr23_+_22656477 5.73 ENSDART00000009337
ENSDART00000133322
enolase 1a, (alpha)
chr20_-_54381034 5.58 ENSDART00000136779
ectonucleoside triphosphate diphosphohydrolase 5b
chr21_-_30254185 5.48 ENSDART00000101054
DnaJ (Hsp40) homolog, subfamily C, member 18
chr20_-_36887176 5.46 ENSDART00000143515
ENSDART00000146994
taxilin beta a
chr16_+_54588930 5.45 ENSDART00000159174
DENN/MADD domain containing 4B
chr20_+_26967154 5.34 ENSDART00000153294
ENSDART00000132434
ENSDART00000143047
AHA1, activator of heat shock protein ATPase homolog 1a
chr23_-_18057270 5.30 ENSDART00000173385
zgc:92287
chr8_+_44926946 5.29 ENSDART00000098567
zgc:154046
chr4_-_2350371 5.28 ENSDART00000166274
pleckstrin homology-like domain, family A, member 1
chr9_-_30145080 4.99 ENSDART00000133746
ABI family, member 3 (NESH) binding protein a
chr23_-_18057851 4.92 ENSDART00000173075
ENSDART00000173230
ENSDART00000173135
ENSDART00000173431
ENSDART00000173068
ENSDART00000172987
zgc:92287
chr8_-_11229523 4.85 ENSDART00000002164
unc-45 myosin chaperone B
chr23_-_32162810 4.77 ENSDART00000155905
nuclear receptor subfamily 4, group A, member 1
chr19_+_43119698 4.71 ENSDART00000167847
ENSDART00000186962
ENSDART00000187305
eukaryotic translation elongation factor 1 alpha 1, like 1
chr11_-_45171139 4.68 ENSDART00000167036
ENSDART00000161712
ENSDART00000158156
synaptogyrin 2b
chr2_+_50999477 4.46 ENSDART00000190111
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr6_+_40629066 4.45 ENSDART00000103757
solute carrier family 6 (neurotransmitter transporter), member 11a
chr12_+_6002715 4.39 ENSDART00000114961
si:ch211-131k2.3
chr22_-_10470663 4.38 ENSDART00000143352
osteomodulin
chr7_-_20582842 4.37 ENSDART00000169750
ENSDART00000111719
si:dkey-19b23.11
chr19_+_30990815 4.35 ENSDART00000134645
syncoilin, intermediate filament protein
chr8_-_51404806 4.32 ENSDART00000060625
leucine-rich repeat LGI family, member 3
chr16_-_31469065 4.30 ENSDART00000182397
si:ch211-251p5.5
chr17_-_22001303 4.29 ENSDART00000122190
solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 2
chr2_+_6253246 4.16 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr1_-_58868306 4.07 ENSDART00000166615
dynamin 2b
chr21_-_5056812 4.06 ENSDART00000139713
ENSDART00000140859
zgc:77838
chr1_-_471925 4.00 ENSDART00000152684
zgc:92518
chr20_+_23625387 3.98 ENSDART00000147945
ENSDART00000150497
palladin, cytoskeletal associated protein
chr9_-_68934 3.97 ENSDART00000054594
ENSDART00000009389
interleukin 10 receptor, beta
chr17_+_132555 3.94 ENSDART00000158159
zgc:77287
chr23_+_553396 3.90 ENSDART00000034707
LSM family member 14B
chr17_-_34963575 3.90 ENSDART00000145664
kinase D-interacting substrate 220a
chr23_-_31633201 3.78 ENSDART00000143335
ENSDART00000053531
solute carrier family 2 (facilitated glucose transporter), member 12
chr18_+_23249519 3.77 ENSDART00000005740
ENSDART00000147446
ENSDART00000124818
myocyte enhancer factor 2aa
chr25_+_17689565 3.59 ENSDART00000171965
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18a
chr9_-_7655243 3.57 ENSDART00000102706
DnaJ (Hsp40) homolog, subfamily B, member 2
chr4_+_10066840 3.53 ENSDART00000026492
filamin C, gamma b (actin binding protein 280)
chr7_+_31838320 3.52 ENSDART00000144679
ENSDART00000174217
ENSDART00000122506
myosin binding protein C, cardiac
chr25_-_29611476 3.49 ENSDART00000154458
si:ch211-253p14.2
chr3_-_62380146 3.48 ENSDART00000155853
G protein-coupled receptor, class C, group 5, member Ba
chr2_+_32016516 3.44 ENSDART00000135040
MYC proto-oncogene, bHLH transcription factor b
chr13_+_228045 3.38 ENSDART00000161091
zgc:64201
chr25_+_13406069 3.36 ENSDART00000010495
zinc and ring finger 1
chr14_+_7939398 3.29 ENSDART00000189773
CXXC finger protein 5b
chr17_-_14836320 3.27 ENSDART00000157051
nidogen 2a (osteonidogen)
chr21_-_217589 3.11 ENSDART00000185017

chr6_-_10964083 3.10 ENSDART00000181583
notum pectinacetylesterase 2
chr18_+_15271993 3.09 ENSDART00000099777
si:dkey-103i16.6
chr25_+_16214854 3.08 ENSDART00000109672
ENSDART00000190093
microtubule associated monooxygenase, calponin and LIM domain containing 2b
chr8_+_4333914 3.04 ENSDART00000137528
myosin, light chain 2b, regulatory, cardiac, slow
chr14_-_32258759 3.01 ENSDART00000052949
fibroblast growth factor 13a
chr14_-_29906209 2.93 ENSDART00000192952
sorbin and SH3 domain containing 2b
chr5_-_48307804 2.85 ENSDART00000182831
ENSDART00000186920
ENSDART00000183585
myocyte enhancer factor 2cb
chr14_+_7939216 2.82 ENSDART00000171657
CXXC finger protein 5b
chr3_-_50865079 2.81 ENSDART00000164295
peripheral myelin protein 22a
chr2_-_17115256 2.81 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr1_-_58880613 2.76 ENSDART00000188136

chr17_-_27048537 2.76 ENSDART00000050018
ENSDART00000193861
connector enhancer of kinase suppressor of Ras 1
chr1_+_27690 2.71 ENSDART00000162928
embryonic ectoderm development
chr18_-_14274803 2.68 ENSDART00000166643
malonyl-CoA decarboxylase
chr16_+_14010242 2.67 ENSDART00000059928
farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
chr2_+_50999675 2.66 ENSDART00000158064
ENSDART00000165746
ENSDART00000163917
ENSDART00000172038
ENSDART00000169048
ENSDART00000164775
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr4_-_18211 2.64 ENSDART00000171737
protein tyrosine phosphatase, non-receptor type 12
chr11_-_101758 2.61 ENSDART00000173015
engulfment and cell motility 2
chr25_-_17587785 2.59 ENSDART00000073679
ENSDART00000146851
zgc:66449
chr7_-_73856073 2.56 ENSDART00000181793

chr6_+_153146 2.52 ENSDART00000097468
zinc finger, GATA-like protein 1
chr5_+_4806851 2.51 ENSDART00000067599
angiopoietin-like 2a
chr16_+_54592907 2.50 ENSDART00000172113
DENN/MADD domain containing 4B
chr10_+_24468922 2.49 ENSDART00000008248
ENSDART00000183510
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr11_-_55224 2.48 ENSDART00000159169
collagen, type II, alpha 1b
chr7_+_67381912 2.46 ENSDART00000167564
nuclear factor of activated T cells 5b
chr3_-_1388936 2.46 ENSDART00000171278
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr8_+_54284961 2.45 ENSDART00000122692
plexin D1
chr22_-_968484 2.45 ENSDART00000105895
calcium channel, voltage-dependent, L type, alpha 1S subunit, a
chr9_+_22657221 2.40 ENSDART00000101765
si:dkey-189g17.2
chr1_+_8508753 2.37 ENSDART00000091683
alkB homolog 5, RNA demethylase
chr4_-_77624155 2.34 ENSDART00000099761
si:ch211-250m6.7
chr23_+_43668756 2.31 ENSDART00000112598
OTU deubiquitinase 4
chr5_+_51226846 2.29 ENSDART00000138210
UBA domain containing 1
chr14_-_30050 2.28 ENSDART00000164411
zinc finger and BTB domain containing 49
chr15_-_12500938 2.27 ENSDART00000159627
sodium channel, voltage-gated, type IV, beta a
chr7_+_46003449 2.23 ENSDART00000159700
ENSDART00000173625
si:ch211-260e23.9
chr8_-_46386024 2.22 ENSDART00000136602
ENSDART00000060919
ENSDART00000137472
glutaminyl-tRNA synthetase
chr2_-_17114852 2.20 ENSDART00000006549
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr2_-_2937225 2.20 ENSDART00000168132
si:ch1073-82l19.1
chr7_-_58130703 2.18 ENSDART00000172082
ankyrin 2b, neuronal
chr12_-_4756478 2.14 ENSDART00000152181
microtubule-associated protein tau a
chr10_+_7636811 2.14 ENSDART00000160673
histidine triad nucleotide binding protein 1
chr12_-_11570 2.14 ENSDART00000186179
shisa family member 6
chr22_-_8509215 2.13 ENSDART00000140146
si:ch73-27e22.3
chr13_-_214122 2.13 ENSDART00000169273
protein phosphatase 1, regulatory subunit 21
chr2_+_258698 2.12 ENSDART00000181330
ENSDART00000181645
PH domain and leucine rich repeat protein phosphatase 1
chr2_-_42393590 2.11 ENSDART00000135529
solute carrier organic anion transporter family member 5A1b
chr20_+_34537736 2.10 ENSDART00000152982
si:ch211-242b18.1
chr25_+_35683956 2.09 ENSDART00000149768
kinesin family member 21A
chr7_-_74090168 2.07 ENSDART00000050528
tyrosinase-related protein 1a
chr19_-_2420990 2.04 ENSDART00000181498
transmembrane protein 196
chr3_+_7771420 2.04 ENSDART00000156809
ENSDART00000156309
hook microtubule-tethering protein 2
chr2_+_32016256 2.03 ENSDART00000005143
MYC proto-oncogene, bHLH transcription factor b
chr9_+_22656976 2.03 ENSDART00000136249
ENSDART00000139270
si:dkey-189g17.2
chr23_+_45845159 2.00 ENSDART00000023944
lamin L3
chr5_+_1515938 1.97 ENSDART00000054057
DDRGK domain containing 1
chr8_+_26410539 1.94 ENSDART00000168780
interferon-related developmental regulator 2
chr17_+_53296851 1.94 ENSDART00000158313
DEAD (Asp-Glu-Ala-Asp) box helicase 24
chr2_+_29995590 1.92 ENSDART00000151906
RNA binding motif protein 33b
chr8_-_8446668 1.92 ENSDART00000132700
cyclin-dependent kinase 16
chr15_-_39969988 1.89 ENSDART00000146054
ribosomal protein S5
chr25_-_20258508 1.89 ENSDART00000133860
ENSDART00000006840
ENSDART00000173434
dynamin 1-like
chr19_+_15441022 1.88 ENSDART00000098970
ENSDART00000140276
lin-28 homolog A (C. elegans)
chr22_-_29336268 1.87 ENSDART00000132776
ENSDART00000186351
ENSDART00000121599
platelet-derived growth factor beta polypeptide a
chr12_+_15165736 1.86 ENSDART00000180398
ADP-ribosylarginine hydrolase
chr19_-_46957968 1.86 ENSDART00000043713
angiopoietin 1
chr12_-_26415499 1.85 ENSDART00000185779
synaptopodin 2-like b
chr7_+_16963091 1.85 ENSDART00000173770
neuron navigator 2a
chr13_-_32726178 1.84 ENSDART00000012232
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr7_+_5911670 1.82 ENSDART00000173025
si:dkey-23a13.9
chr2_+_47708853 1.81 ENSDART00000124307
muscleblind-like splicing regulator 1
chr5_-_32336613 1.81 ENSDART00000139732
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr23_-_27505825 1.80 ENSDART00000137229
ENSDART00000013797
ankyrin repeat and SOCS box containing 8
chr25_-_3549321 1.78 ENSDART00000181214
ENSDART00000160600
haloacid dehalogenase like hydrolase domain containing 5
chr9_-_41025062 1.78 ENSDART00000002053
PMS1 homolog 1, mismatch repair system component
chr10_+_45059702 1.77 ENSDART00000166945
NudC domain containing 3
chr4_+_3980247 1.74 ENSDART00000049194
G protein-coupled receptor 37b
chr3_+_57788761 1.74 ENSDART00000149741
si:ch73-362i18.1
chr8_-_43677762 1.71 ENSDART00000167762
E1A binding protein p400
chr5_+_7564644 1.71 ENSDART00000192173

chr12_-_10508952 1.68 ENSDART00000152806
zgc:152977
chr4_-_5597802 1.67 ENSDART00000136229
vascular endothelial growth factor Ab
chr14_+_36497250 1.66 ENSDART00000184727
si:dkey-237h12.3
chr18_-_17724295 1.66 ENSDART00000121553
family with sequence similarity 192, member A
chr4_-_8093753 1.64 ENSDART00000133434
WNK lysine deficient protein kinase 1b
chr8_+_1284784 1.63 ENSDART00000061663
F-box and leucine-rich repeat protein 17
chr8_-_45838481 1.63 ENSDART00000148206
ENSDART00000170485
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr11_+_7214353 1.62 ENSDART00000156764
NACHT and WD repeat domain containing 1
chr6_-_9952103 1.62 ENSDART00000065475
zona pellucida glycoprotein 2, like 2
chr2_-_7666021 1.61 ENSDART00000180007

chr18_-_10995410 1.61 ENSDART00000136751
tetraspanin 33b
chr23_-_1583193 1.61 ENSDART00000143841
fibronectin type III domain containing 7b
chr13_-_24745288 1.60 ENSDART00000031564
SWI5-dependent homologous recombination repair protein 1
chr3_+_17251542 1.60 ENSDART00000024832
signal transducer and activator of transcription 5a
chr5_+_6796291 1.57 ENSDART00000166868
ENSDART00000165308
malic enzyme 2, NAD(+)-dependent, mitochondrial
chr9_+_51891 1.55 ENSDART00000163529
zgc:158316
chr10_-_690072 1.54 ENSDART00000164871
ENSDART00000142833
GLIS family zinc finger 3
chr8_-_45838277 1.54 ENSDART00000046064
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr25_-_36365977 1.52 ENSDART00000152546
zgc:173552
chr12_-_49166761 1.52 ENSDART00000189407
acyl-CoA dehydrogenase short/branched chain
chr8_-_26609259 1.50 ENSDART00000027301
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr14_+_21828993 1.50 ENSDART00000144367
C-terminal binding protein 1
chr7_-_6368406 1.50 ENSDART00000172787
histone cluster 1 H2A family member 11
chr8_+_26410197 1.50 ENSDART00000145836
ENSDART00000053447
interferon-related developmental regulator 2
chr16_-_41059919 1.50 ENSDART00000188803
si:dkey-201i6.8
chr16_+_41873708 1.49 ENSDART00000084631
ENSDART00000084639
ENSDART00000058611
sodium channel, voltage-gated, type I, beta a
chr7_-_41468751 1.48 ENSDART00000150146
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr20_+_46268906 1.48 ENSDART00000113372
trace amine associated receptor 14e
chr9_-_17783574 1.47 ENSDART00000146706
von Willebrand factor A domain containing 8
chr7_-_69636502 1.47 ENSDART00000126739
tetraspanin 5a
chr18_+_40584288 1.47 ENSDART00000087692
si:ch211-132b12.3

Network of associatons between targets according to the STRING database.

First level regulatory network of myog

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 21.7 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
4.8 19.2 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
3.5 14.1 GO:0006740 NADPH regeneration(GO:0006740)
3.2 9.6 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
2.2 8.6 GO:0014856 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
1.9 9.4 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
1.5 12.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
1.4 12.8 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
1.4 24.8 GO:0051764 actin crosslink formation(GO:0051764)
1.2 5.8 GO:0097066 response to thyroid hormone(GO:0097066)
1.1 8.0 GO:0033292 T-tubule organization(GO:0033292)
1.1 9.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
1.1 5.7 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
1.0 16.6 GO:0048769 sarcomerogenesis(GO:0048769)
0.8 3.1 GO:1990697 protein depalmitoleylation(GO:1990697)
0.8 15.9 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.7 1.5 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.7 3.5 GO:0003210 cardiac atrium formation(GO:0003210)
0.6 2.4 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.6 2.3 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.5 2.7 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.5 8.0 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.5 3.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.5 4.4 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.5 5.3 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.5 3.8 GO:0046323 glucose import(GO:0046323)
0.5 1.9 GO:0048014 Tie signaling pathway(GO:0048014)
0.5 7.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.4 2.7 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.4 6.1 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.4 1.3 GO:0019264 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
0.4 5.0 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.4 2.0 GO:1990564 IRE1-mediated unfolded protein response(GO:0036498) negative regulation of response to endoplasmic reticulum stress(GO:1903573) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.4 1.6 GO:0006108 malate metabolic process(GO:0006108)
0.4 1.9 GO:1903146 regulation of mitophagy(GO:1903146)
0.4 1.1 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.4 1.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.3 2.4 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
0.3 1.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 5.6 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.3 1.2 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.3 4.4 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.3 1.4 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.3 0.5 GO:0042026 protein refolding(GO:0042026)
0.3 2.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.3 1.6 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.3 1.3 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3 2.1 GO:0042438 melanin biosynthetic process(GO:0042438)
0.2 0.7 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 4.2 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 0.7 GO:0071918 urea transmembrane transport(GO:0071918)
0.2 1.2 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.2 2.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.2 2.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 1.2 GO:0007624 ultradian rhythm(GO:0007624)
0.2 0.7 GO:0044406 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.2 1.8 GO:2000725 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.2 9.4 GO:0061386 closure of optic fissure(GO:0061386)
0.2 22.4 GO:0061515 myeloid cell development(GO:0061515)
0.2 1.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 0.6 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.2 1.9 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.2 8.5 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.2 1.2 GO:1902946 protein localization to early endosome(GO:1902946)
0.2 1.5 GO:0051673 membrane disruption in other organism(GO:0051673)
0.2 8.9 GO:0000187 activation of MAPK activity(GO:0000187)
0.2 0.7 GO:0006844 acyl carnitine transport(GO:0006844)
0.2 1.5 GO:0021871 forebrain regionalization(GO:0021871)
0.2 2.3 GO:2000651 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.2 2.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 4.4 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.2 0.9 GO:0035989 tendon development(GO:0035989)
0.2 0.8 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.2 1.7 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.2 2.7 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.7 GO:0016037 light absorption(GO:0016037)
0.1 1.3 GO:0070293 renal absorption(GO:0070293)
0.1 9.2 GO:0006414 translational elongation(GO:0006414)
0.1 1.4 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.9 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 1.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.4 GO:1901380 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 0.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 1.2 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 4.1 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 2.8 GO:0055013 cardiac muscle cell development(GO:0055013)
0.1 11.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 6.3 GO:0006342 chromatin silencing(GO:0006342)
0.1 0.5 GO:0060074 synapse maturation(GO:0060074)
0.1 2.4 GO:0035476 angioblast cell migration(GO:0035476)
0.1 4.2 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.1 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.1 0.5 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.6 GO:0035889 otolith tethering(GO:0035889)
0.1 8.5 GO:0006400 tRNA modification(GO:0006400)
0.1 0.7 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.8 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 2.5 GO:0003323 type B pancreatic cell development(GO:0003323)
0.1 1.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.5 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.1 0.8 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 0.6 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.8 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 0.6 GO:0030728 ovulation(GO:0030728)
0.1 1.3 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.5 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.1 1.6 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 9.6 GO:0030239 myofibril assembly(GO:0030239)
0.1 5.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.8 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 1.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.9 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 1.8 GO:0006298 mismatch repair(GO:0006298)
0.1 2.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 1.0 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.1 0.8 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 2.8 GO:0048599 oocyte development(GO:0048599)
0.1 0.3 GO:0072574 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.1 0.5 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 3.0 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 1.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.9 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.5 GO:0045727 positive regulation of translation(GO:0045727)
0.1 0.2 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.0 0.3 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 3.5 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 1.0 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.8 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 1.0 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 1.2 GO:0016574 histone ubiquitination(GO:0016574)
0.0 1.3 GO:0009261 purine ribonucleotide catabolic process(GO:0009154) ribonucleotide catabolic process(GO:0009261)
0.0 1.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.7 GO:0060021 palate development(GO:0060021)
0.0 1.1 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 24.2 GO:0016567 protein ubiquitination(GO:0016567)
0.0 0.8 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.0 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 2.0 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 1.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.5 GO:0009060 aerobic respiration(GO:0009060)
0.0 1.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.6 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 2.3 GO:0003341 cilium movement(GO:0003341)
0.0 0.6 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.7 GO:0019835 cytolysis(GO:0019835)
0.0 2.6 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 1.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 3.4 GO:0051604 protein maturation(GO:0051604)
0.0 0.3 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 3.1 GO:0007018 microtubule-based movement(GO:0007018)
0.0 1.5 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 2.0 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.4 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 1.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 3.2 GO:0043410 positive regulation of MAPK cascade(GO:0043410)
0.0 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.3 GO:0046474 glycerophospholipid biosynthetic process(GO:0046474)
0.0 0.5 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 2.6 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 1.8 GO:0006909 phagocytosis(GO:0006909)
0.0 0.1 GO:0061511 centriole elongation(GO:0061511)
0.0 0.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.1 GO:0006972 hyperosmotic response(GO:0006972)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 19.2 GO:0031673 H zone(GO:0031673)
1.5 12.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
1.4 36.9 GO:0031672 A band(GO:0031672)
1.3 9.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
1.0 7.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.7 15.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.7 31.4 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.6 3.5 GO:0070062 extracellular exosome(GO:0070062)
0.4 2.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.4 4.4 GO:0045171 intercellular bridge(GO:0045171)
0.3 13.7 GO:0005861 troponin complex(GO:0005861)
0.3 3.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 1.2 GO:0033503 HULC complex(GO:0033503)
0.2 2.2 GO:0030315 T-tubule(GO:0030315)
0.2 0.7 GO:0097541 axonemal basal plate(GO:0097541)
0.2 3.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 1.6 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.2 5.8 GO:0031594 neuromuscular junction(GO:0031594)
0.2 22.2 GO:0005884 actin filament(GO:0005884)
0.2 1.8 GO:0032300 mismatch repair complex(GO:0032300)
0.2 2.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 1.2 GO:0043194 axon initial segment(GO:0043194)
0.2 1.3 GO:0070552 BRISC complex(GO:0070552)
0.2 15.8 GO:0000786 nucleosome(GO:0000786)
0.1 2.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 2.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.5 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.1 2.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 2.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 2.4 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 1.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 9.4 GO:0005604 basement membrane(GO:0005604)
0.1 12.1 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.1 4.7 GO:0005657 replication fork(GO:0005657)
0.1 1.0 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 1.3 GO:1990391 DNA repair complex(GO:1990391)
0.1 1.4 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 21.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 1.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.3 GO:0043195 terminal bouton(GO:0043195)
0.1 7.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 3.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 2.7 GO:0030426 growth cone(GO:0030426)
0.0 4.3 GO:0005871 kinesin complex(GO:0005871)
0.0 1.2 GO:0016529 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.0 1.3 GO:0008305 integrin complex(GO:0008305)
0.0 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.0 2.5 GO:0030018 Z disc(GO:0030018)
0.0 2.7 GO:0005581 collagen trimer(GO:0005581)
0.0 1.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.3 GO:0030286 dynein complex(GO:0030286)
0.0 3.4 GO:0005882 intermediate filament(GO:0005882)
0.0 2.1 GO:0005776 autophagosome(GO:0005776)
0.0 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.8 GO:0032590 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 3.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 1.1 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 5.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 6.3 GO:0005730 nucleolus(GO:0005730)
0.0 0.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 5.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.6 GO:0016607 nuclear speck(GO:0016607)
0.0 1.2 GO:0030027 lamellipodium(GO:0030027)
0.0 3.8 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 14.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
2.3 9.3 GO:0071253 connexin binding(GO:0071253)
1.5 12.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
1.4 5.7 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
1.3 4.0 GO:0004904 interferon receptor activity(GO:0004904)
1.2 13.7 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
1.1 19.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.0 5.0 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
1.0 14.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.9 2.7 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.8 3.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.6 2.4 GO:1990931 RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.5 2.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.5 3.1 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.5 6.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.5 5.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.5 5.9 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.4 8.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.4 1.3 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.4 1.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.4 10.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.4 4.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.4 3.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.4 1.6 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.4 4.2 GO:0035804 structural constituent of egg coat(GO:0035804)
0.4 1.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.3 7.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3 3.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 2.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.3 4.9 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.3 2.6 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.3 13.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.3 0.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 1.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 0.7 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 6.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 10.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 1.9 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 3.1 GO:0070403 NAD+ binding(GO:0070403)
0.2 0.8 GO:0070699 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.2 2.3 GO:0043495 protein anchor(GO:0043495)
0.2 0.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 0.7 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.2 0.9 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.2 0.9 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.2 22.9 GO:0042803 protein homodimerization activity(GO:0042803)
0.2 0.5 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.1 1.2 GO:0034452 dynactin binding(GO:0034452)
0.1 2.3 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 0.7 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 10.3 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 3.9 GO:0030165 PDZ domain binding(GO:0030165)
0.1 2.2 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 2.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 1.2 GO:0030332 cyclin binding(GO:0030332)
0.1 12.2 GO:0019905 syntaxin binding(GO:0019905)
0.1 0.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 4.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.4 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 1.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.8 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 3.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.8 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 1.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.3 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.1 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.2 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 1.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 2.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.7 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 12.2 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.1 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 3.3 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 2.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 9.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 4.7 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.5 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 3.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 17.3 GO:0051015 actin filament binding(GO:0051015)
0.1 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 1.7 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 3.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 9.1 GO:0005267 potassium channel activity(GO:0005267)
0.0 4.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.6 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.5 GO:0043022 ribosome binding(GO:0043022)
0.0 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 1.5 GO:0051287 NAD binding(GO:0051287)
0.0 1.2 GO:0046332 SMAD binding(GO:0046332)
0.0 1.0 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 3.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.3 GO:0042562 hormone binding(GO:0042562)
0.0 7.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 3.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.8 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 1.8 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 7.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.4 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 2.7 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 11.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.6 GO:0019843 rRNA binding(GO:0019843)
0.0 0.4 GO:0044325 ion channel binding(GO:0044325)
0.0 1.1 GO:0019955 cytokine binding(GO:0019955)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 10.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 4.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 9.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 7.5 PID BMP PATHWAY BMP receptor signaling
0.2 6.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 4.4 PID IL3 PATHWAY IL3-mediated signaling events
0.1 1.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 5.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.5 PID ATM PATHWAY ATM pathway
0.1 1.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 4.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.2 PID AURORA B PATHWAY Aurora B signaling
0.0 1.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 19.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.6 6.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.5 3.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.3 6.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.3 1.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 1.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 6.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 2.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.2 3.9 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 1.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 2.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.9 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.2 REACTOME KINESINS Genes involved in Kinesins
0.1 1.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 8.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.0 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.9 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.9 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 1.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.1 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 3.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors