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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for nfia

Z-value: 2.40

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Transcription factors associated with nfia

Gene Symbol Gene ID Gene Info
nfia
ENSDARG00000062420 nuclear factor I/A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfiadr11_v1_chr22_-_16997887_16997887-0.232.3e-02Click!

Activity profile of nfia motif

Sorted Z-values of nfia motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_13256415 41.09 ENSDART00000144542
atp2a1l
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr5_+_32228538 38.78 ENSDART00000077471
myhc4
myosin heavy chain 4
chr12_-_17712393 37.47 ENSDART00000143534
ENSDART00000010144
pvalb2
parvalbumin 2
chr5_+_32222303 37.33 ENSDART00000051362
myhc4
myosin heavy chain 4
chr5_-_32292965 33.14 ENSDART00000183522
ENSDART00000131983
myhz1.2
myosin, heavy polypeptide 1.2, skeletal muscle
chr5_+_32247310 31.76 ENSDART00000182649
myha
myosin, heavy chain a
chr7_+_29951997 29.15 ENSDART00000173453
tpma
alpha-tropomyosin
chr5_-_71705191 26.24 ENSDART00000187767
ak1
adenylate kinase 1
chr15_-_23645810 26.12 ENSDART00000168845
ckmb
creatine kinase, muscle b
chr16_+_29650698 22.24 ENSDART00000137153
tmod4
tropomodulin 4 (muscle)
chr25_+_20081553 22.24 ENSDART00000174684
tnni4b.1
troponin I4b, tandem duplicate 1
chr23_-_21515182 21.93 ENSDART00000142000
rnf207b
ring finger protein 207b
chr9_-_6927587 21.35 ENSDART00000059092
tmem182a
transmembrane protein 182a
chr14_-_7128980 21.32 ENSDART00000171311
si:ch73-43g23.1
si:ch73-43g23.1
chr5_-_32309129 20.68 ENSDART00000123003
myhz1.1
myosin, heavy polypeptide 1.1, skeletal muscle
chr3_+_31039923 19.16 ENSDART00000147706
cox6a2
cytochrome c oxidase subunit VIa polypeptide 2
chr3_+_23221047 18.95 ENSDART00000009393
col1a1a
collagen, type I, alpha 1a
chr25_+_20089986 18.30 ENSDART00000143441
ENSDART00000184073
tnni4b.2
troponin I4b, tandem duplicate 2
chr2_+_2470687 18.00 ENSDART00000184024
ENSDART00000061955
myl13
myosin, light chain 13
chr13_+_50375800 17.61 ENSDART00000099537
cox5b2
cytochrome c oxidase subunit Vb 2
chr17_-_6382392 17.59 ENSDART00000188051
ENSDART00000192560
ENSDART00000137389
ENSDART00000115389
txlnbb
taxilin beta b
chr23_+_20110086 17.33 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr23_-_32162810 17.20 ENSDART00000155905
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr2_+_394166 16.09 ENSDART00000155733
mylk4a
myosin light chain kinase family, member 4a
chr21_-_11632403 15.40 ENSDART00000171708
ENSDART00000138619
ENSDART00000136308
ENSDART00000144770
cast
calpastatin
chr22_-_263117 14.42 ENSDART00000158134
zgc:66156
zgc:66156
chr21_+_21374277 14.25 ENSDART00000079431
rtn2b
reticulon 2b
chr23_+_31107685 13.74 ENSDART00000103448
tbx18
T-box 18
chr22_-_294700 13.72 ENSDART00000189179
CABZ01079179.1

chr9_-_42696408 13.21 ENSDART00000144744
col5a2a
collagen, type V, alpha 2a
chr21_-_22730832 13.09 ENSDART00000101797
fbxo40.1
F-box protein 40, tandem duplicate 1
chr4_+_26357221 13.03 ENSDART00000187684
ENSDART00000101545
ENSDART00000148296
ENSDART00000171433
tnni1d
troponin I, skeletal, slow d
chr21_+_10866421 12.46 ENSDART00000137858
alpk2
alpha-kinase 2
chr7_-_41851605 12.39 ENSDART00000142981
mylk3
myosin light chain kinase 3
chr22_+_28446365 12.21 ENSDART00000189359
abi3bpb
ABI family, member 3 (NESH) binding protein b
chr19_-_9648542 12.09 ENSDART00000172628
clcn1a
chloride channel, voltage-sensitive 1a
chr20_-_27311675 12.03 ENSDART00000026088
ENSDART00000148361
asb2a.1
ankyrin repeat and SOCS box containing 2a, tandem duplicate 1
chr22_+_16308450 11.97 ENSDART00000105678
lrrc39
leucine rich repeat containing 39
chr8_+_46217861 11.95 ENSDART00000038790
angptl7
angiopoietin-like 7
chr24_-_29822913 11.79 ENSDART00000160929
aglb
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b
chr18_-_26101800 11.79 ENSDART00000004692
idh2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr13_+_24834199 11.77 ENSDART00000101274
zgc:153981
zgc:153981
chr22_+_16308806 11.45 ENSDART00000162685
lrrc39
leucine rich repeat containing 39
chr6_-_46782176 11.34 ENSDART00000185559
igfn1.4
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 4
chr8_-_14121634 11.23 ENSDART00000184946
bgna
biglycan a
chr22_-_26945493 11.07 ENSDART00000077411
cxcl12b
chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)
chr13_-_17723417 11.01 ENSDART00000183834
vdac2
voltage-dependent anion channel 2
chr10_+_15608326 11.00 ENSDART00000188770
zfand5b
zinc finger, AN1-type domain 5b
chr24_-_24038800 10.02 ENSDART00000080549
lyz
lysozyme
chr12_+_6195191 9.73 ENSDART00000043236
ENSDART00000186420
prkg1b
protein kinase, cGMP-dependent, type Ib
chr20_+_3934516 9.68 ENSDART00000165732
clec11a
C-type lectin domain containing 11A
chr12_-_26415499 9.50 ENSDART00000185779
synpo2lb
synaptopodin 2-like b
chr16_-_13595027 9.23 ENSDART00000060004
ntd5
ntl-dependent gene 5
chr4_-_16412084 9.22 ENSDART00000188460
dcn
decorin
chr1_-_41192059 9.03 ENSDART00000084665
ENSDART00000135369
dok7
docking protein 7
chr9_-_35633827 9.03 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr23_+_5524247 8.99 ENSDART00000189679
ENSDART00000083622
tead3a
TEA domain family member 3 a
chr9_-_33107237 8.79 ENSDART00000013918
casq2
calsequestrin 2
chr14_-_30808174 8.71 ENSDART00000173262
prss23
protease, serine, 23
chr3_-_50046004 8.47 ENSDART00000109544
si:ch1073-100f3.2
si:ch1073-100f3.2
chr15_+_21882419 8.30 ENSDART00000157216
si:dkey-103g5.4
si:dkey-103g5.4
chr5_-_48268049 8.09 ENSDART00000187454
mef2cb
myocyte enhancer factor 2cb
chr15_-_29387446 8.02 ENSDART00000145976
ENSDART00000035096
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr4_-_17785120 7.98 ENSDART00000024775
mybpc1
myosin binding protein C, slow type
chr13_+_35635672 7.95 ENSDART00000148481
thbs2a
thrombospondin 2a
chr9_-_6372535 7.94 ENSDART00000149189
ecrg4a
esophageal cancer related gene 4a
chr4_+_22480169 7.75 ENSDART00000146272
ENSDART00000066904
ndufb2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr6_-_15641686 7.72 ENSDART00000135583
mlpha
melanophilin a
chr17_-_45040813 7.72 ENSDART00000075514
entpd5a
ectonucleoside triphosphate diphosphohydrolase 5a
chr5_+_53482597 7.62 ENSDART00000180333
BX323994.1

chr24_-_38197040 7.61 ENSDART00000137949
ENSDART00000105639
igic1s1
immunoglobulin light iota constant 1, s1
chr18_+_23218980 7.56 ENSDART00000185014
mef2aa
myocyte enhancer factor 2aa
chr3_-_50865079 7.47 ENSDART00000164295
pmp22a
peripheral myelin protein 22a
chr7_-_23745984 7.34 ENSDART00000048050
ITGB1BP2
zgc:92429
chr6_-_52566574 7.27 ENSDART00000098421
uqcc1
ubiquinol-cytochrome c reductase complex assembly factor 1
chr13_+_35689749 7.24 ENSDART00000158726
psme4a
proteasome activator subunit 4a
chr25_-_10503043 7.24 ENSDART00000155404
cox8b
cytochrome c oxidase subunit 8b
chr24_+_9298198 7.21 ENSDART00000165780
otud1
OTU deubiquitinase 1
chr13_+_36633355 7.14 ENSDART00000135612
si:ch211-67f24.7
si:ch211-67f24.7
chr10_-_21542702 7.08 ENSDART00000146761
ENSDART00000134502
zgc:165539
zgc:165539
chr20_-_39273987 7.05 ENSDART00000127173
clu
clusterin
chr14_-_21064199 7.01 ENSDART00000172099
si:dkey-74k8.3
si:dkey-74k8.3
chr7_-_34294613 7.00 ENSDART00000191632
CR388195.1

chr7_-_16558665 6.97 ENSDART00000169399
csrp3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr19_+_19412692 6.95 ENSDART00000113580
wu:fc38h03
wu:fc38h03
chr5_+_24287927 6.92 ENSDART00000143563
zdhhc23a
zinc finger, DHHC-type containing 23a
chr8_+_48613040 6.62 ENSDART00000121432
nppa
natriuretic peptide A
chr2_-_5404466 6.54 ENSDART00000152907
si:ch1073-184j22.2
si:ch1073-184j22.2
chr4_-_77114795 6.53 ENSDART00000144849
CU467646.2

chr16_-_43356018 6.41 ENSDART00000181683
FO704821.1

chr13_+_23162447 6.34 ENSDART00000180209
sorbs1
sorbin and SH3 domain containing 1
chr5_-_51830997 6.30 ENSDART00000163616
homer1b
homer scaffolding protein 1b
chr9_-_30160897 6.25 ENSDART00000143986
abi3bpa
ABI family, member 3 (NESH) binding protein a
chr13_+_35690023 6.23 ENSDART00000128865
ENSDART00000130050
psme4a
proteasome activator subunit 4a
chr7_+_12835048 6.20 ENSDART00000016465
cx36.7
connexin 36.7
chr2_+_31600661 6.08 ENSDART00000139039
si:ch211-106h4.4
si:ch211-106h4.4
chr24_+_21174523 5.96 ENSDART00000183849
naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr7_+_35238234 5.96 ENSDART00000178732
tppp3
tubulin polymerization-promoting protein family member 3
chr7_-_13750108 5.85 ENSDART00000173014
kbtbd13
kelch repeat and BTB (POZ) domain containing 13
chr4_-_77624155 5.85 ENSDART00000099761
si:ch211-250m6.7
si:ch211-250m6.7
chr3_+_55100045 5.81 ENSDART00000113098
hbaa1
hemoglobin, alpha adult 1
chr5_+_51909740 5.79 ENSDART00000162541
thbs4a
thrombospondin 4a
chr1_-_58900851 5.76 ENSDART00000183085
ENSDART00000188855
ENSDART00000182567
CABZ01084501.3
Danio rerio microfibril-associated glycoprotein 4-like (LOC100334800), transcript variant 2, mRNA.
chr5_-_57655092 5.73 ENSDART00000074290
mia
melanoma inhibitory activity
chr8_-_17997845 5.57 ENSDART00000121660
acot11b
acyl-CoA thioesterase 11b
chr16_-_17525322 5.53 ENSDART00000189720
clcn1b
chloride channel, voltage-sensitive 1b
chr25_-_20523927 5.53 ENSDART00000114448
si:ch211-269c21.2
si:ch211-269c21.2
chr24_+_21174851 5.50 ENSDART00000154940
ENSDART00000155977
ENSDART00000122762
naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr14_-_21063977 5.49 ENSDART00000164373
si:dkey-74k8.3
si:dkey-74k8.3
chr21_-_20832482 5.46 ENSDART00000191928
c6
complement component 6
chr22_+_38767780 5.31 ENSDART00000149499
alpi.1
alkaline phosphatase, intestinal, tandem duplicate 1
chr16_+_20915319 5.28 ENSDART00000079383
hoxa9b
homeobox A9b
chr15_-_4152582 5.24 ENSDART00000171942
si:dkey-83h2.5
si:dkey-83h2.5
chr3_+_55105066 5.22 ENSDART00000110848
si:ch211-5k11.8
si:ch211-5k11.8
chr15_+_5277761 5.21 ENSDART00000153954
si:ch1073-166e24.4
si:ch1073-166e24.4
chr21_+_40484088 5.19 ENSDART00000161919
coro6
coronin 6
chr10_+_43189325 5.17 ENSDART00000185584
vcanb
versican b
chr13_+_30804367 5.16 ENSDART00000053946
cxcl12a
chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)
chr1_+_47178529 5.10 ENSDART00000158432
ENSDART00000074450
ENSDART00000137448
morc3b
MORC family CW-type zinc finger 3b
chr3_-_58644920 5.08 ENSDART00000155953
dhrs7ca
dehydrogenase/reductase (SDR family) member 7Ca
chr12_+_23850661 5.07 ENSDART00000152921
svila
supervillin a
chr7_-_17028015 5.03 ENSDART00000022441
dbx1a
developing brain homeobox 1a
chr12_+_30563550 5.03 ENSDART00000126064
si:ch211-28p3.4
si:ch211-28p3.4
chr24_+_34069675 5.00 ENSDART00000143995
si:ch211-190p8.2
si:ch211-190p8.2
chr1_-_1627487 4.99 ENSDART00000166094
clic6
chloride intracellular channel 6
chr20_-_39273505 4.96 ENSDART00000153114
clu
clusterin
chr21_-_2958422 4.95 ENSDART00000174091
zgc:194215
zgc:194215
chr18_+_44649804 4.94 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr14_+_30328567 4.93 ENSDART00000105889
mtus1a
microtubule associated tumor suppressor 1a
chr15_-_29388012 4.92 ENSDART00000115032
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr4_-_77561679 4.84 ENSDART00000180809
AL935186.9

chr19_-_46957968 4.81 ENSDART00000043713
angpt1
angiopoietin 1
chr12_+_30723778 4.77 ENSDART00000153291
slc35f3a
solute carrier family 35, member F3a
chr19_-_35361556 4.77 ENSDART00000012167
ndufs5
NADH dehydrogenase (ubiquinone) Fe-S protein 5
chr10_-_44008241 4.77 ENSDART00000137686
acads
acyl-CoA dehydrogenase short chain
chr14_-_41467497 4.70 ENSDART00000181220
mid1ip1l
MID1 interacting protein 1, like
chr21_-_20840714 4.69 ENSDART00000144861
ENSDART00000139430
c6
complement component 6
chr11_+_13630107 4.69 ENSDART00000172220
si:ch211-1a19.3
si:ch211-1a19.3
chr14_-_29906209 4.64 ENSDART00000192952
sorbs2b
sorbin and SH3 domain containing 2b
chr7_+_24628546 4.57 ENSDART00000173745
MSMP
si:ch211-69e13.6
chr19_-_24163845 4.49 ENSDART00000133277
prf1.2
perforin 1.2
chr5_-_9073433 4.44 ENSDART00000099891
atp5meb
ATP synthase membrane subunit eb
chr15_-_34567370 4.39 ENSDART00000099793
sostdc1a
sclerostin domain containing 1a
chr10_+_26901222 4.34 ENSDART00000188766
ehbp1l1b
EH domain binding protein 1-like 1b
chr1_+_40801696 4.29 ENSDART00000147497
cpz
carboxypeptidase Z
chr9_-_2572790 4.28 ENSDART00000135076
ENSDART00000016710
scrn3
secernin 3
chr8_-_23884301 4.28 ENSDART00000185509
ENSDART00000147202
lhfpl5b
LHFPL tetraspan subfamily member 5b
chr14_-_3268155 4.27 ENSDART00000177244
pdgfrb
platelet-derived growth factor receptor, beta polypeptide
chr24_+_15602 4.26 ENSDART00000161519
CABZ01109081.1

chr20_-_49681850 4.24 ENSDART00000025926
col12a1b
collagen, type XII, alpha 1b
chr1_-_22851481 4.24 ENSDART00000054386
qdprb1
quinoid dihydropteridine reductase b1
chr25_+_34014523 4.22 ENSDART00000182856
anxa2a
annexin A2a
chr16_+_12521872 4.19 ENSDART00000114411
rasip1
Ras interacting protein 1
chr16_-_5721386 4.19 ENSDART00000136655
ndufa3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
chr4_-_55728559 4.16 ENSDART00000186201
CT583728.14

chr6_-_7082108 4.16 ENSDART00000081760
ihhb
Indian hedgehog homolog b
chr4_+_36489448 4.16 ENSDART00000143181
znf1149
zinc finger protein 1149
chr12_-_684200 4.12 ENSDART00000152122
si:ch211-176g6.2
si:ch211-176g6.2
chr5_-_28679135 4.10 ENSDART00000193585
tnc
tenascin C
chr21_+_16980141 4.02 ENSDART00000101241
aqp3b
aquaporin 3b
chr20_-_31743817 4.02 ENSDART00000137679
sash1a
SAM and SH3 domain containing 1a
chr11_+_18037729 4.02 ENSDART00000111624
zgc:175135
zgc:175135
chr5_+_28160503 4.00 ENSDART00000051516
tacr1a
tachykinin receptor 1a
chr17_+_38573471 3.99 ENSDART00000040627
sptb
spectrin, beta, erythrocytic
chr7_-_21905851 3.99 ENSDART00000111066
ENSDART00000020288
epoa
erythropoietin a
chr2_+_38161318 3.94 ENSDART00000044264
mmp14b
matrix metallopeptidase 14b (membrane-inserted)
chr20_-_44496245 3.92 ENSDART00000012229
fkbp1b
FK506 binding protein 1b
chr11_+_18157260 3.90 ENSDART00000144659
zgc:173545
zgc:173545
chr7_+_49877148 3.89 ENSDART00000174182
slc1a2a
solute carrier family 1 (glial high affinity glutamate transporter), member 2a
chr14_-_41468892 3.86 ENSDART00000173099
ENSDART00000003170
mid1ip1l
MID1 interacting protein 1, like
chr21_+_25777425 3.84 ENSDART00000021620
cldnd
claudin d
chr18_-_20816103 3.84 ENSDART00000143233
cttnbp2
cortactin binding protein 2
chr23_-_16734009 3.83 ENSDART00000125449
si:ch211-224l10.4
si:ch211-224l10.4
chr5_-_24642026 3.83 ENSDART00000139522
si:ch211-106a19.1
si:ch211-106a19.1
chr11_+_18130300 3.80 ENSDART00000169146
zgc:175135
zgc:175135
chr15_+_37986069 3.76 ENSDART00000156984
si:dkey-238d18.8
si:dkey-238d18.8
chr5_+_28161079 3.75 ENSDART00000141109
tacr1a
tachykinin receptor 1a
chr21_-_43656125 3.75 ENSDART00000136392
ENSDART00000192805
ENSDART00000181960
si:ch211-263m18.4
si:dkey-229d11.5
si:ch211-263m18.4
si:dkey-229d11.5
chr5_+_37517800 3.73 ENSDART00000048107
FP102018.1
Danio rerio latent transforming growth factor beta binding protein 3 (ltbp3), mRNA.
chr22_+_17248145 3.71 ENSDART00000136908
axdnd1
axonemal dynein light chain domain containing 1
chr23_+_20689255 3.69 ENSDART00000182420
usp21
ubiquitin specific peptidase 21
chr24_-_38205133 3.69 ENSDART00000108739
ENSDART00000193369
igl3v5
immunoglobulin light 3 variable 5
chr12_+_35654749 3.68 ENSDART00000169889
ENSDART00000167873
baiap2b
BAI1-associated protein 2b
chr6_+_26948093 3.66 ENSDART00000153595
farp2
FERM, RhoGEF and pleckstrin domain protein 2
chr23_+_16469530 3.66 ENSDART00000132898
ntsr1
neurotensin receptor 1 (high affinity)
chr7_+_73308566 3.60 ENSDART00000187039
ENSDART00000174244
CABZ01081777.1

chr14_+_18785727 3.57 ENSDART00000184452
si:ch211-111e20.1
si:ch211-111e20.1
chr9_-_53422084 3.57 ENSDART00000162661
gpc6b
glypican 6b
chr24_-_5910811 3.57 ENSDART00000163012
pcolce2b
procollagen C-endopeptidase enhancer 2b
chr21_-_43649959 3.57 ENSDART00000142733
si:dkey-229d11.5
si:dkey-229d11.5
chr18_+_23193820 3.53 ENSDART00000148106
mef2aa
myocyte enhancer factor 2aa
chr17_+_24613255 3.48 ENSDART00000064738
atp5if1b
ATP synthase inhibitory factor subunit 1b
chr9_+_15890558 3.47 ENSDART00000144032
si:dkey-14o1.20
si:dkey-14o1.20
chr5_+_51079504 3.46 ENSDART00000097466
fam169aa
family with sequence similarity 169, member Aa
chr17_+_33453689 3.46 ENSDART00000156894
rin3
Ras and Rab interactor 3
chr7_-_33829824 3.45 ENSDART00000074729
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr1_+_2712956 3.44 ENSDART00000126093
gpc6a
glypican 6a
chr13_+_50778187 3.41 ENSDART00000159597
dntt
deoxynucleotidyltransferase, terminal
chr10_+_19569052 3.40 ENSDART00000058425
CABZ01059627.1

chr13_-_8815530 3.39 ENSDART00000122498
si:ch73-105b23.6
si:ch73-105b23.6

Network of associatons between targets according to the STRING database.

First level regulatory network of nfia

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 21.9 GO:1903779 regulation of cardiac conduction(GO:1903779)
4.7 18.9 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
4.1 16.2 GO:0021730 trigeminal sensory nucleus development(GO:0021730)
3.9 11.8 GO:0006097 glyoxylate cycle(GO:0006097)
3.1 40.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
3.0 21.3 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
2.9 11.5 GO:0034087 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
2.6 7.9 GO:0070314 G1 to G0 transition(GO:0070314)
2.6 7.7 GO:0042220 response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
2.5 12.5 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
2.5 22.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
2.2 13.5 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
2.2 6.6 GO:1905072 cardiac jelly development(GO:1905072)
2.2 15.4 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
2.2 8.8 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
2.1 12.4 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
2.0 26.1 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
1.9 7.7 GO:0051876 pigment granule dispersal(GO:0051876)
1.9 17.2 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
1.7 7.0 GO:0035994 response to muscle stretch(GO:0035994)
1.7 5.1 GO:0061178 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
1.7 8.5 GO:0015743 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
1.6 4.7 GO:0015874 norepinephrine transport(GO:0015874)
1.5 5.9 GO:0048014 Tie signaling pathway(GO:0048014)
1.4 70.9 GO:0003009 skeletal muscle contraction(GO:0003009)
1.4 4.1 GO:0014814 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
1.2 7.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
1.2 4.8 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.2 3.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
1.2 3.5 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
1.1 3.2 GO:0097623 potassium ion export(GO:0071435) potassium ion export across plasma membrane(GO:0097623)
1.1 4.3 GO:0014909 smooth muscle cell migration(GO:0014909)
1.0 4.2 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
1.0 3.0 GO:0021985 neurohypophysis development(GO:0021985)
0.9 4.7 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.9 2.7 GO:0045218 zonula adherens maintenance(GO:0045218)
0.9 6.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.9 4.3 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.8 11.8 GO:0009251 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.8 9.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.8 3.3 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.8 2.5 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.8 2.4 GO:0000711 meiotic DNA repair synthesis(GO:0000711) chiasma assembly(GO:0051026)
0.8 24.8 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.8 7.7 GO:0072506 phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.8 3.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.7 2.9 GO:2000583 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.7 9.7 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.7 4.2 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.7 2.0 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.6 17.7 GO:0001757 somite specification(GO:0001757)
0.6 18.2 GO:0019835 cytolysis(GO:0019835)
0.6 13.1 GO:0015671 oxygen transport(GO:0015671)
0.6 1.8 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.6 11.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.6 5.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.6 2.9 GO:0060401 cytosolic calcium ion transport(GO:0060401) calcium ion transport into cytosol(GO:0060402)
0.6 4.0 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.5 5.2 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.5 2.6 GO:2000319 regulation of T-helper 17 type immune response(GO:2000316) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320) regulation of T-helper 17 cell lineage commitment(GO:2000328) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.5 1.5 GO:0042908 xenobiotic transport(GO:0042908)
0.5 2.0 GO:0061010 gall bladder development(GO:0061010)
0.5 2.0 GO:0018343 protein farnesylation(GO:0018343)
0.5 3.3 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.5 1.8 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.5 2.3 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.5 2.3 GO:0048909 dorsal spinal cord development(GO:0021516) anterior lateral line nerve development(GO:0048909)
0.5 3.2 GO:0021570 rhombomere 4 development(GO:0021570) rhombomere 4 morphogenesis(GO:0021661)
0.4 3.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.4 2.1 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.4 1.3 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.4 1.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.4 1.6 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.4 2.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.4 18.5 GO:0055013 cardiac muscle cell development(GO:0055013)
0.4 1.1 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.4 1.1 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.3 2.1 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.3 2.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.3 2.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.3 5.0 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.3 18.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.3 9.2 GO:0010508 positive regulation of autophagy(GO:0010508)
0.3 1.9 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.3 2.9 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3 1.3 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.3 2.8 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.3 1.8 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.3 1.2 GO:0019532 oxalate transport(GO:0019532)
0.3 1.5 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.3 1.8 GO:0021535 cell migration in hindbrain(GO:0021535)
0.3 2.4 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.3 8.7 GO:0035329 hippo signaling(GO:0035329)
0.3 3.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 1.1 GO:0051610 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.3 5.6 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.3 1.6 GO:0006465 signal peptide processing(GO:0006465)
0.3 8.2 GO:0051014 actin filament severing(GO:0051014)
0.3 30.8 GO:0006936 muscle contraction(GO:0006936)
0.3 2.6 GO:0070309 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.3 1.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 3.1 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.3 2.3 GO:0003160 endocardium morphogenesis(GO:0003160)
0.3 1.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.3 6.5 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.2 7.2 GO:0030199 collagen fibril organization(GO:0030199)
0.2 3.6 GO:0007602 phototransduction(GO:0007602)
0.2 1.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 15.4 GO:1901214 regulation of neuron death(GO:1901214)
0.2 0.7 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.2 1.1 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.2 1.1 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.2 2.5 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.2 1.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 1.7 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 24.0 GO:0001756 somitogenesis(GO:0001756)
0.2 52.8 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.2 8.5 GO:2000181 negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)
0.2 2.2 GO:0048769 sarcomerogenesis(GO:0048769)
0.2 24.5 GO:0006821 chloride transport(GO:0006821)
0.2 8.1 GO:0032456 endocytic recycling(GO:0032456)
0.2 2.3 GO:0008272 sulfate transport(GO:0008272)
0.2 4.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.3 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.2 0.9 GO:0090200 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.2 4.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 1.2 GO:0060017 parathyroid gland development(GO:0060017)
0.2 0.7 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.2 1.7 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.2 0.5 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.2 4.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.2 0.3 GO:0090109 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109) regulation of adherens junction organization(GO:1903391)
0.2 0.7 GO:0030224 monocyte differentiation(GO:0030224)
0.2 0.7 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.2 35.6 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.2 0.5 GO:0071634 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
0.2 3.7 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.2 0.5 GO:0036159 inner dynein arm assembly(GO:0036159)
0.2 3.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.2 2.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 4.2 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 1.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 7.2 GO:0006119 oxidative phosphorylation(GO:0006119)
0.1 1.1 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.1 2.0 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1 2.3 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 5.5 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.4 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 6.8 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.1 2.0 GO:0036065 fucosylation(GO:0036065)
0.1 3.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 8.9 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.1 3.4 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 1.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 0.5 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.4 GO:0044878 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.1 3.5 GO:0051693 actin filament capping(GO:0051693)
0.1 1.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 2.3 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 10.0 GO:0048469 cell maturation(GO:0048469)
0.1 1.2 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 0.7 GO:0050909 sensory perception of taste(GO:0050909)
0.1 3.0 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.1 2.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.1 GO:0070189 kynurenine metabolic process(GO:0070189)
0.1 1.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 4.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 2.0 GO:0048747 muscle fiber development(GO:0048747)
0.1 3.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 8.3 GO:0006334 nucleosome assembly(GO:0006334)
0.1 1.0 GO:0007608 sensory perception of smell(GO:0007608)
0.1 15.8 GO:0007601 visual perception(GO:0007601)
0.1 0.9 GO:0006032 chitin catabolic process(GO:0006032) glucosamine-containing compound catabolic process(GO:1901072)
0.1 6.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 3.3 GO:0009880 embryonic pattern specification(GO:0009880)
0.1 1.2 GO:0030259 lipid glycosylation(GO:0030259)
0.1 1.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 2.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 2.6 GO:0001570 vasculogenesis(GO:0001570)
0.1 1.9 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 4.7 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.1 1.3 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.1 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.6 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.2 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.9 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 1.9 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.4 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.4 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.2 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 2.7 GO:0031101 fin regeneration(GO:0031101)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.9 GO:0051262 protein tetramerization(GO:0051262)
0.0 0.5 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 2.9 GO:0048545 response to steroid hormone(GO:0048545)
0.0 0.8 GO:0009081 branched-chain amino acid metabolic process(GO:0009081)
0.0 3.3 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 6.7 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 1.8 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 1.3 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.4 GO:0001503 ossification(GO:0001503)
0.0 1.4 GO:0007098 centrosome cycle(GO:0007098) centrosome organization(GO:0051297)
0.0 1.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.2 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 6.0 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.2 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.4 GO:0001935 endothelial cell proliferation(GO:0001935)
0.0 0.2 GO:0014020 primary neural tube formation(GO:0014020)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 13.5 GO:1990111 spermatoproteasome complex(GO:1990111)
3.3 13.2 GO:0005588 collagen type V trimer(GO:0005588)
2.3 11.5 GO:0031415 NatA complex(GO:0031415)
1.9 5.7 GO:0044316 cone cell pedicle(GO:0044316)
1.6 70.9 GO:0005861 troponin complex(GO:0005861)
1.6 22.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
1.4 7.2 GO:0045277 respiratory chain complex IV(GO:0045277)
1.4 14.4 GO:0042583 chromaffin granule(GO:0042583)
1.4 35.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
1.4 22.2 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
1.3 168.6 GO:0016459 myosin complex(GO:0016459)
1.3 8.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.2 29.2 GO:0046930 pore complex(GO:0046930)
1.2 23.4 GO:0031430 M band(GO:0031430)
1.1 13.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.1 8.4 GO:0097225 sperm midpiece(GO:0097225)
0.8 4.0 GO:0008091 spectrin(GO:0008091)
0.8 3.8 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.7 1.4 GO:0035253 ciliary rootlet(GO:0035253)
0.6 2.4 GO:0043073 germ cell nucleus(GO:0043073)
0.5 2.0 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.5 3.7 GO:0030428 cell septum(GO:0030428)
0.5 2.7 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.5 1.4 GO:0010369 chromocenter(GO:0010369)
0.4 1.8 GO:0005614 interstitial matrix(GO:0005614)
0.4 18.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 18.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 1.9 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.3 30.7 GO:0031674 I band(GO:0031674)
0.3 1.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.3 1.3 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.3 1.3 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.3 1.1 GO:0033186 CAF-1 complex(GO:0033186)
0.3 4.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 26.5 GO:0005884 actin filament(GO:0005884)
0.3 4.7 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.3 3.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.3 23.4 GO:0005581 collagen trimer(GO:0005581)
0.3 3.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 3.1 GO:0005922 connexon complex(GO:0005922)
0.2 5.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 1.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 6.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.2 1.9 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 0.6 GO:0043034 costamere(GO:0043034)
0.2 0.9 GO:0032433 filopodium tip(GO:0032433)
0.2 0.9 GO:0005883 neurofilament(GO:0005883)
0.2 1.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 0.8 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.2 0.8 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 1.7 GO:0030017 sarcomere(GO:0030017)
0.1 1.9 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 1.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 116.2 GO:0005615 extracellular space(GO:0005615)
0.1 2.5 GO:0045180 basal cortex(GO:0045180)
0.1 33.1 GO:0031012 extracellular matrix(GO:0031012)
0.1 0.7 GO:1990130 Iml1 complex(GO:1990130)
0.1 2.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 4.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 2.0 GO:0031594 neuromuscular junction(GO:0031594)
0.1 3.0 GO:0016605 PML body(GO:0016605)
0.1 7.2 GO:0000786 nucleosome(GO:0000786)
0.1 4.9 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.2 GO:0000795 synaptonemal complex(GO:0000795)
0.1 1.7 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 1.4 GO:0032420 stereocilium(GO:0032420)
0.1 4.9 GO:0030139 endocytic vesicle(GO:0030139)
0.1 19.3 GO:0005667 transcription factor complex(GO:0005667)
0.1 4.7 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.1 13.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 1.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.2 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 3.5 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.0 3.7 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 10.9 GO:0005874 microtubule(GO:0005874)
0.0 2.1 GO:0014069 postsynaptic density(GO:0014069)
0.0 2.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.0 GO:0005814 centriole(GO:0005814)
0.0 32.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.0 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.8 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
2.9 11.8 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
2.6 7.7 GO:0016496 substance P receptor activity(GO:0016496)
2.5 10.0 GO:0003796 lysozyme activity(GO:0003796)
2.2 11.0 GO:0015288 porin activity(GO:0015288)
2.2 15.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
2.2 28.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
2.1 35.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
2.0 26.1 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
1.7 8.5 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
1.7 47.3 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.6 21.3 GO:0004017 adenylate kinase activity(GO:0004017)
1.6 9.7 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
1.6 4.7 GO:0005333 dopamine transmembrane transporter activity(GO:0005329) dopamine:sodium symporter activity(GO:0005330) norepinephrine transmembrane transporter activity(GO:0005333) norepinephrine:sodium symporter activity(GO:0005334)
1.6 17.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
1.5 21.9 GO:0030544 Hsp70 protein binding(GO:0030544)
1.4 4.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.3 13.5 GO:0016504 peptidase activator activity(GO:0016504)
1.3 4.0 GO:0005128 erythropoietin receptor binding(GO:0005128)
1.3 6.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
1.1 11.5 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
1.1 3.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
1.1 13.1 GO:0031720 haptoglobin binding(GO:0031720)
1.1 19.5 GO:0008308 voltage-gated chloride channel activity(GO:0005247) voltage-gated anion channel activity(GO:0008308)
1.1 4.3 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
1.0 22.2 GO:0005523 tropomyosin binding(GO:0005523)
1.0 4.0 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.9 2.7 GO:0070097 delta-catenin binding(GO:0070097)
0.9 4.3 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.8 4.7 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.8 16.2 GO:0042056 chemoattractant activity(GO:0042056)
0.7 3.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.7 172.4 GO:0003774 motor activity(GO:0003774)
0.7 5.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.6 1.9 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.6 1.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.6 23.1 GO:0005518 collagen binding(GO:0005518)
0.6 16.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.6 2.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.5 4.4 GO:0036122 BMP binding(GO:0036122)
0.5 14.4 GO:0051787 misfolded protein binding(GO:0051787)
0.5 2.0 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.5 2.0 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.5 3.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.5 3.7 GO:0004100 chitin synthase activity(GO:0004100)
0.5 3.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.5 4.2 GO:0005113 patched binding(GO:0005113)
0.5 2.3 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.5 7.7 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.5 1.8 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.4 7.3 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.4 2.1 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.4 51.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.4 2.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.4 1.9 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.4 1.1 GO:0005335 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.4 1.1 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.4 2.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 1.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.3 18.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 6.5 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.3 2.3 GO:0070888 E-box binding(GO:0070888)
0.3 4.2 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.3 8.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 4.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.3 1.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.3 2.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.3 10.6 GO:0051020 GTPase binding(GO:0051020)
0.3 1.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.3 1.8 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.3 8.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.3 14.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.3 3.7 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.3 1.9 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.3 1.8 GO:0016972 thiol oxidase activity(GO:0016972)
0.3 7.0 GO:0042805 actinin binding(GO:0042805)
0.2 1.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 3.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 1.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 2.1 GO:0008494 translation activator activity(GO:0008494)
0.2 3.0 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 7.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.8 GO:0043394 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.2 1.5 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.2 19.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 0.9 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2 1.9 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 3.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 0.8 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.2 24.0 GO:0042803 protein homodimerization activity(GO:0042803)
0.2 3.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.2 14.9 GO:0008201 heparin binding(GO:0008201)
0.2 3.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 2.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 1.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 4.7 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.2 1.1 GO:0016805 dipeptidase activity(GO:0016805)
0.2 17.6 GO:0019905 syntaxin binding(GO:0019905)
0.2 0.7 GO:0004995 tachykinin receptor activity(GO:0004995)
0.2 3.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.7 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172) L-aspartate transmembrane transporter activity(GO:0015183)
0.1 5.7 GO:0017022 myosin binding(GO:0017022)
0.1 1.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 3.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 5.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 10.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.3 GO:0032190 acrosin binding(GO:0032190)
0.1 10.1 GO:0005254 chloride channel activity(GO:0005254)
0.1 1.1 GO:0005243 gap junction channel activity(GO:0005243)
0.1 3.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 2.0 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 4.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 2.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 15.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 1.0 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 3.8 GO:0005109 frizzled binding(GO:0005109)
0.1 5.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 4.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.8 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 2.2 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.1 0.9 GO:0004568 chitinase activity(GO:0004568)
0.1 0.8 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 1.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.8 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 3.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 6.0 GO:0042802 identical protein binding(GO:0042802)
0.1 1.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 5.5 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 1.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 7.3 GO:0008083 growth factor activity(GO:0008083)
0.1 4.4 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 3.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 2.2 GO:0019956 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.1 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.1 11.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 5.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 6.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 2.1 GO:0044325 ion channel binding(GO:0044325)
0.0 5.3 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.6 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 25.2 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.3 GO:0048018 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 1.0 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 7.6 GO:0015631 tubulin binding(GO:0015631)
0.0 4.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.4 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 1.7 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 20.7 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 17.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.4 24.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.4 9.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 10.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.3 4.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 5.7 PID AP1 PATHWAY AP-1 transcription factor network
0.1 6.3 PID INSULIN PATHWAY Insulin Pathway
0.1 2.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 10.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 1.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 16.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 3.6 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 4.2 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 2.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.9 PID E2F PATHWAY E2F transcription factor network
0.0 2.0 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 20.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.7 9.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.6 11.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.6 18.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.6 14.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.4 3.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.4 10.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.4 3.0 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.4 20.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 4.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3 2.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 4.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.3 2.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 6.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 2.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 6.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 2.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 3.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 5.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 1.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 3.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 6.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 1.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 4.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 6.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.7 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 1.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 2.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 2.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production