ISMARA results: nfia

Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation

Downloads

Results for nfia

Z-value: 2.40

Motif logo

Transcription factors associated with nfia

Gene Symbol	Gene ID	Gene Info
nfia NCBI UniProt	ENSDARG00000062420	nuclear factor I/A

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
nfia	dr11_v1_chr22_-_16997887_16997887	-0.23	2.3e-02	Click!

Activity profile of nfia motif

Sorted Z-values of nfia motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr12_+_13256415 Show fit	41.09	ENSDART00000144542	atp2a1l NCBI UniProt Show fit	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr5_+_32228538 Show fit	38.78	ENSDART00000077471	myhc4 NCBI UniProt Show fit	myosin heavy chain 4
chr12_-_17712393 Show fit	37.47	ENSDART00000143534 ENSDART00000010144	pvalb2 NCBI UniProt Show fit	parvalbumin 2
chr5_+_32222303 Show fit	37.33	ENSDART00000051362	myhc4 NCBI UniProt Show fit	myosin heavy chain 4
chr5_-_32292965 Show fit	33.14	ENSDART00000183522 ENSDART00000131983	myhz1.2 NCBI UniProt Show fit	myosin, heavy polypeptide 1.2, skeletal muscle
chr5_+_32247310 Show fit	31.76	ENSDART00000182649	myha NCBI UniProt Show fit	myosin, heavy chain a
chr7_+_29951997 Show fit	29.15	ENSDART00000173453	tpma NCBI UniProt Show fit	alpha-tropomyosin
chr5_-_71705191 Show fit	26.24	ENSDART00000187767	ak1 NCBI UniProt Show fit	adenylate kinase 1
chr15_-_23645810 Show fit	26.12	ENSDART00000168845	ckmb NCBI UniProt Show fit	creatine kinase, muscle b
chr16_+_29650698 Show fit	22.24	ENSDART00000137153	tmod4 NCBI UniProt Show fit	tropomodulin 4 (muscle)

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of nfia

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	70.9	GO:0003009	skeletal muscle contraction(GO:0003009)
0.2	52.8	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
3.1	40.1	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2	35.6	GO:0070588	calcium ion transmembrane transport(GO:0070588)
0.3	30.8	GO:0006936	muscle contraction(GO:0006936)
2.0	26.1	GO:0006603	phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.8	24.8	GO:0055008	cardiac muscle tissue morphogenesis(GO:0055008)
0.2	24.5	GO:0006821	chloride transport(GO:0006821)
0.2	24.0	GO:0001756	somitogenesis(GO:0001756)
2.5	22.2	GO:0051694	pointed-end actin filament capping(GO:0051694)

Showing 1 to 10 of 213 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	168.6	GO:0016459	myosin complex(GO:0016459)
0.1	116.2	GO:0005615	extracellular space(GO:0005615)
1.6	70.9	GO:0005861	troponin complex(GO:0005861)
1.4	35.3	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.1	33.1	GO:0031012	extracellular matrix(GO:0031012)
0.0	32.3	GO:0005887	integral component of plasma membrane(GO:0005887)
0.3	30.7	GO:0031674	I band(GO:0031674)
1.2	29.2	GO:0046930	pore complex(GO:0046930)
0.3	26.5	GO:0005884	actin filament(GO:0005884)
1.2	23.4	GO:0031430	M band(GO:0031430)

Showing 1 to 10 of 85 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	172.4	GO:0003774	motor activity(GO:0003774)
0.4	51.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)
1.7	47.3	GO:0016675	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
2.1	35.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
2.2	28.5	GO:0004687	myosin light chain kinase activity(GO:0004687)
2.0	26.1	GO:0016775	creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0	25.2	GO:0005509	calcium ion binding(GO:0005509)
0.2	24.0	GO:0042803	protein homodimerization activity(GO:0042803)
0.6	23.1	GO:0005518	collagen binding(GO:0005518)
1.0	22.2	GO:0005523	tropomyosin binding(GO:0005523)

Showing 1 to 10 of 170 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	24.2	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.8	17.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	16.8	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	10.4	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3	10.3	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.4	9.2	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	6.3	PID INSULIN PATHWAY	Insulin Pathway
0.1	5.7	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	4.2	PID CMYB PATHWAY	C-MYB transcription factor network
0.3	4.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events

Showing 1 to 10 of 23 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	20.8	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4	20.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.6	18.3	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.6	14.6	REACTOME AMYLOIDS	Genes involved in Amyloids
0.6	11.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.4	10.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.7	9.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.3	6.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.3	6.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	6.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation

Showing 1 to 10 of 45 entries

Results for nfia

Z-value: 2.40

Motif logo

Transcription factors associated with nfia

Activity-expression correlation:

Activity profile of nfia motif

Sorted Z-values of nfia motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of nfia

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: