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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for nkx2.2a

Z-value: 0.64

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Transcription factors associated with nkx2.2a

Gene Symbol Gene ID Gene Info
nkx2.2a
ENSDARG00000053298 NK2 homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx2.2adr11_v1_chr17_-_42213822_422138220.214.5e-02Click!

Activity profile of nkx2.2a motif

Sorted Z-values of nkx2.2a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_3629201 5.11 ENSDART00000136577
ENSDART00000132121
itih3a
inter-alpha-trypsin inhibitor heavy chain 3a
chr25_-_7974494 3.99 ENSDART00000171446
hal
histidine ammonia-lyase
chr19_+_9344171 3.67 ENSDART00000133447
ENSDART00000104622
si:ch211-288g17.4
si:ch211-288g17.4
chr7_+_41295974 3.64 ENSDART00000173568
ENSDART00000173544
si:dkey-86l18.10
si:dkey-86l18.10
chr8_-_39739627 3.15 ENSDART00000135422
ENSDART00000067844
si:ch211-170d8.5
si:ch211-170d8.5
chr8_-_39739056 3.06 ENSDART00000147992
si:ch211-170d8.5
si:ch211-170d8.5
chr24_-_2829049 2.84 ENSDART00000164913
PPP1R3G
si:ch211-152c8.5
chr2_+_1486822 2.81 ENSDART00000132500
c8a
complement component 8, alpha polypeptide
chr2_+_1487118 2.74 ENSDART00000147283
c8a
complement component 8, alpha polypeptide
chr20_+_53577502 2.70 ENSDART00000126983
myh6
myosin, heavy chain 6, cardiac muscle, alpha
chr17_-_14726824 2.70 ENSDART00000162947
si:ch73-305o9.3
si:ch73-305o9.3
chr16_-_25400257 2.67 ENSDART00000040756
zgc:136493
zgc:136493
chr13_-_18637244 2.58 ENSDART00000057869
mat1a
methionine adenosyltransferase I, alpha
chr22_-_24757785 2.52 ENSDART00000078225
vtg5
vitellogenin 5
chr2_-_20052561 2.36 ENSDART00000100133
dpydb
dihydropyrimidine dehydrogenase b
chr7_-_69636502 2.22 ENSDART00000126739
tspan5a
tetraspanin 5a
chr13_+_47710434 2.12 ENSDART00000188724
TMEM87B
transmembrane protein 87B
chr13_-_40726865 2.06 ENSDART00000099847
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr20_-_6812688 2.03 ENSDART00000170934
igfbp1a
insulin-like growth factor binding protein 1a
chr21_+_9628854 1.98 ENSDART00000161753
ENSDART00000160711
mapk10
mitogen-activated protein kinase 10
chr5_+_31965845 1.98 ENSDART00000112968
myo1hb
myosin IHb
chr1_-_23294753 1.94 ENSDART00000013263
ugdh
UDP-glucose 6-dehydrogenase
chr3_+_12829566 1.93 ENSDART00000157672
si:ch211-8c17.2
si:ch211-8c17.2
chr14_-_42997145 1.92 ENSDART00000172801
pcdh10b
protocadherin 10b
chr1_+_45323142 1.89 ENSDART00000132210
emp1
epithelial membrane protein 1
chr25_-_32311048 1.88 ENSDART00000181806
ENSDART00000086334
CU372926.1

chr12_-_19865585 1.85 ENSDART00000066386
shisa9a
shisa family member 9a
chr8_+_31248917 1.81 ENSDART00000112170
unm_hu7912
un-named hu7912
chr14_-_24110251 1.77 ENSDART00000079226
cpeb4a
cytoplasmic polyadenylation element binding protein 4a
chr6_+_10338554 1.77 ENSDART00000186936
cobll1a
cordon-bleu WH2 repeat protein-like 1a
chr14_-_24110062 1.77 ENSDART00000177062
cpeb4a
cytoplasmic polyadenylation element binding protein 4a
chr1_+_15137901 1.73 ENSDART00000111475
pcdh7a
protocadherin 7a
chr10_+_21807497 1.73 ENSDART00000164634
pcdh1g32
protocadherin 1 gamma 32
chr10_+_34394454 1.72 ENSDART00000110121
stard13a
StAR-related lipid transfer (START) domain containing 13a
chr24_-_7699356 1.72 ENSDART00000013117
syt5b
synaptotagmin Vb
chr1_+_37196106 1.72 ENSDART00000008756
ENSDART00000157503
ENSDART00000162971
ENSDART00000191004
ENSDART00000078206
ENSDART00000045111
dclk2a
doublecortin-like kinase 2a
chr9_+_21722733 1.67 ENSDART00000102021
sox1a
SRY (sex determining region Y)-box 1a
chr6_+_20650003 1.67 ENSDART00000049465
slc19a1
solute carrier family 19 (folate transporter), member 1
chr19_+_30867845 1.67 ENSDART00000047461
mfsd2ab
major facilitator superfamily domain containing 2ab
chr15_-_44601331 1.66 ENSDART00000161514
zgc:165508
zgc:165508
chr4_-_72609735 1.62 ENSDART00000174299
ENSDART00000159227
si:cabz01054394.6
si:cabz01054394.6
chr19_+_1184878 1.58 ENSDART00000163539
scrt1a
scratch family zinc finger 1a
chr15_+_28106498 1.58 ENSDART00000041707
unc119a
unc-119 homolog a (C. elegans)
chr21_-_42055872 1.58 ENSDART00000144767
gabra1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr13_+_29352842 1.56 ENSDART00000113009
ogdhl
oxoglutarate dehydrogenase like
chr16_-_41465542 1.55 ENSDART00000169116
ENSDART00000187446
cpne4a
copine IVa
chr23_+_6795531 1.53 ENSDART00000092131
si:ch211-117c9.5
si:ch211-117c9.5
chr21_+_39948300 1.53 ENSDART00000137740
slc47a1
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr24_-_31332087 1.53 ENSDART00000161179
abcd3a
ATP-binding cassette, sub-family D (ALD), member 3a
chr23_-_27701361 1.51 ENSDART00000186688
ENSDART00000183985
dnajc22
DnaJ (Hsp40) homolog, subfamily C, member 22
chr25_+_35375848 1.51 ENSDART00000155721
ano3
anoctamin 3
chr24_-_33308045 1.50 ENSDART00000149711
slc4a2b
solute carrier family 4 (anion exchanger), member 2b
chr5_+_72087619 1.47 ENSDART00000062885
oxt
oxytocin
chr7_+_73447724 1.47 ENSDART00000040786
cbln6
cerebellin 6
chr9_-_9998087 1.45 ENSDART00000124423
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr19_+_37848830 1.44 ENSDART00000042276
ENSDART00000180872
nxph1
neurexophilin 1
chr15_+_24691088 1.44 ENSDART00000110618
LRRC75A
si:dkey-151p21.7
chr11_+_42422371 1.44 ENSDART00000163780
dennd6aa
DENN/MADD domain containing 6Aa
chr12_+_36413886 1.40 ENSDART00000126325
si:ch211-250n8.1
si:ch211-250n8.1
chr1_-_45888608 1.39 ENSDART00000139219
pnpla6
patatin-like phospholipase domain containing 6
chr4_+_37992753 1.38 ENSDART00000193890
CR759843.2

chr6_+_10094061 1.38 ENSDART00000150998
ENSDART00000162236
atp7b
ATPase copper transporting beta
chr19_-_32940040 1.37 ENSDART00000179947
azin1b
antizyme inhibitor 1b
chr18_-_40481028 1.37 ENSDART00000134177
zgc:101040
zgc:101040
chr1_+_17695426 1.32 ENSDART00000103236
ankrd37
ankyrin repeat domain 37
chr8_-_14484599 1.30 ENSDART00000057644
lhx4
LIM homeobox 4
chr23_+_4362463 1.30 ENSDART00000039829
zgc:112175
zgc:112175
chr24_+_22039964 1.29 ENSDART00000081220
ankrd33ba
ankyrin repeat domain 33ba
chr16_-_31284922 1.29 ENSDART00000142638
mroh1
maestro heat-like repeat family member 1
chr24_+_12200260 1.27 ENSDART00000181391
CR855257.2

chr14_-_24110707 1.27 ENSDART00000133522
ENSDART00000123152
cpeb4a
cytoplasmic polyadenylation element binding protein 4a
chr2_-_24270062 1.24 ENSDART00000192445
myh7
myosin heavy chain 7
chr16_-_12097394 1.24 ENSDART00000103944
pex5
peroxisomal biogenesis factor 5
chr8_+_28065803 1.23 ENSDART00000178481
kcnd3
potassium voltage-gated channel, Shal-related subfamily, member 3
chr13_-_29424454 1.23 ENSDART00000026765
slc18a3a
solute carrier family 18 (vesicular acetylcholine transporter), member 3a
chr15_-_20731297 1.23 ENSDART00000114464
tpst1
tyrosylprotein sulfotransferase 1
chr13_-_24379271 1.23 ENSDART00000046360
rhoua
ras homolog family member Ua
chr14_-_25985698 1.23 ENSDART00000172909
ENSDART00000123053
atox1
antioxidant 1 copper chaperone
chr2_-_37280028 1.23 ENSDART00000139459
nadkb
NAD kinase b
chr8_+_8845932 1.21 ENSDART00000112028
si:ch211-180f4.1
si:ch211-180f4.1
chr9_-_51323545 1.20 ENSDART00000139316
slc4a10b
solute carrier family 4, sodium bicarbonate transporter, member 10b
chr5_+_9408901 1.18 ENSDART00000193364
FP236810.1

chr6_+_49255706 1.18 ENSDART00000156866
si:dkey-183k8.2
si:dkey-183k8.2
chr20_+_32756763 1.17 ENSDART00000023006
fam84a
family with sequence similarity 84, member A
chr5_+_32009080 1.15 ENSDART00000186885
scai
suppressor of cancer cell invasion
chr11_-_29623380 1.15 ENSDART00000162587
ENSDART00000193935
ENSDART00000191646
chd5
chromodomain helicase DNA binding protein 5
chr20_-_28349144 1.14 ENSDART00000179690
ENSDART00000188059
ino80
INO80 complex subunit
chr19_+_24039830 1.14 ENSDART00000100422
rit1
Ras-like without CAAX 1
chr5_-_60159116 1.14 ENSDART00000147675
si:dkey-280e8.1
si:dkey-280e8.1
chr19_-_677713 1.13 ENSDART00000025146
slc6a19a.1
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 1
chr6_+_9793791 1.13 ENSDART00000149896
als2b
amyotrophic lateral sclerosis 2b (juvenile)
chr21_-_25573064 1.12 ENSDART00000134310
CR388166.1

chr2_+_38924975 1.12 ENSDART00000109219
rem2
RAS (RAD and GEM)-like GTP binding 2
chr5_+_54685175 1.11 ENSDART00000115016
pmchl
pro-melanin-concentrating hormone, like
chr7_-_26518086 1.11 ENSDART00000058913
eif4a1a
eukaryotic translation initiation factor 4A1A
chr4_+_19535946 1.11 ENSDART00000192342
ENSDART00000183740
ENSDART00000180812
ENSDART00000180017
lrrc4.1
leucine rich repeat containing 4.1
chr23_+_6795709 1.11 ENSDART00000149136
si:ch211-117c9.5
si:ch211-117c9.5
chr4_-_18436899 1.10 ENSDART00000141671
socs2
suppressor of cytokine signaling 2
chr16_+_17763848 1.10 ENSDART00000149408
ENSDART00000148878
them4
thioesterase superfamily member 4
chr6_-_10168822 1.10 ENSDART00000151016
b3galt1a
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1a
chr21_+_11684830 1.09 ENSDART00000147473
pcsk1
proprotein convertase subtilisin/kexin type 1
chr17_+_30205258 1.08 ENSDART00000076596
ENSDART00000153795
spata17
spermatogenesis associated 17
chr3_+_24134418 1.05 ENSDART00000156204
si:ch211-246i5.5
si:ch211-246i5.5
chr13_+_33368140 1.05 ENSDART00000033848
brf1a
BRF1, RNA polymerase III transcription initiation factor a
chr2_-_11662851 1.03 ENSDART00000145108
zgc:110130
zgc:110130
chr1_-_625875 1.03 ENSDART00000167331
appa
amyloid beta (A4) precursor protein a
chr2_+_33052169 1.03 ENSDART00000180008
rnf220a
ring finger protein 220a
chr3_+_49521106 1.02 ENSDART00000162799
crb3a
crumbs homolog 3a
chr20_+_27020201 1.02 ENSDART00000126919
ENSDART00000016014
chga
chromogranin A
chr24_+_5935377 1.01 ENSDART00000191989
ENSDART00000185932
ENSDART00000131768
abi1a
abl-interactor 1a
chr12_+_16281312 0.99 ENSDART00000152500
ppp1r3cb
protein phosphatase 1, regulatory subunit 3Cb
chr23_-_24856025 0.99 ENSDART00000142171
syt6a
synaptotagmin VIa
chr25_-_30047477 0.98 ENSDART00000164859
CR759810.1

chr2_+_22531185 0.98 ENSDART00000171959
hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr13_+_28675686 0.98 ENSDART00000027213
inaa
internexin neuronal intermediate filament protein, alpha a
chrM_+_12897 0.96 ENSDART00000093622
mt-nd5
NADH dehydrogenase 5, mitochondrial
chr15_+_19472129 0.95 ENSDART00000154779
zgc:77784
zgc:77784
chr25_+_36152215 0.95 ENSDART00000036147
irx5b
iroquois homeobox 5b
chr2_+_7557912 0.94 ENSDART00000160053
ripk2
receptor-interacting serine-threonine kinase 2
chr16_-_22225295 0.94 ENSDART00000163519
LO017682.1

chr21_+_11685009 0.93 ENSDART00000014668
pcsk1
proprotein convertase subtilisin/kexin type 1
chr9_-_23156908 0.92 ENSDART00000135461
lypd6b
LY6/PLAUR domain containing 6B
chr13_-_23270576 0.92 ENSDART00000132828
si:dkey-103j14.5
si:dkey-103j14.5
chr18_-_14937211 0.92 ENSDART00000141893
mlc1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr11_-_3954691 0.92 ENSDART00000182041
pbrm1
polybromo 1
chr8_+_14058646 0.90 ENSDART00000080852
ugt5e1
UDP glucuronosyltransferase 5 family, polypeptide E1
chr6_+_4872883 0.90 ENSDART00000186730
ENSDART00000092290
ENSDART00000151674
pcdh9
protocadherin 9
chr17_+_10501647 0.90 ENSDART00000140391
tyro3
TYRO3 protein tyrosine kinase
chr23_-_39784368 0.89 ENSDART00000110282
si:ch211-286f9.2
si:ch211-286f9.2
chr19_-_22328154 0.89 ENSDART00000090464
si:ch73-196l6.5
si:ch73-196l6.5
chr14_+_3449780 0.88 ENSDART00000163849
trpc3
transient receptor potential cation channel, subfamily C, member 3
chr3_+_40856095 0.88 ENSDART00000143207
mmd2a
monocyte to macrophage differentiation-associated 2a
chr23_+_36730713 0.88 ENSDART00000113179
tspan31
tetraspanin 31
chr15_-_13254480 0.87 ENSDART00000190499
zgc:172282
zgc:172282
chr8_+_3431671 0.86 ENSDART00000017850
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr8_-_18262149 0.86 ENSDART00000143000
rnf220b
ring finger protein 220b
chr4_-_41269844 0.86 ENSDART00000186177
CR388165.2

chr4_+_2230701 0.85 ENSDART00000080439
cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr9_+_50600355 0.85 ENSDART00000187567
fign
fidgetin
chr13_-_32995324 0.85 ENSDART00000140542
ENSDART00000037740
kcnf1b
potassium voltage-gated channel, subfamily F, member 1b
chr23_+_40460333 0.85 ENSDART00000184658
soga3b
SOGA family member 3b
chr8_-_1698155 0.84 ENSDART00000186159
CABZ01065417.1

chr4_+_13412030 0.83 ENSDART00000003694
cand1
cullin-associated and neddylation-dissociated 1
chr2_+_31437547 0.82 ENSDART00000141170
stam
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr5_+_20035284 0.81 ENSDART00000191808
sgsm1a
small G protein signaling modulator 1a
chr4_+_18824959 0.81 ENSDART00000146141
ENSDART00000040424
slc26a3.1
solute carrier family 26 (anion exchanger), member 3
chr14_-_49133426 0.81 ENSDART00000042421
ppp2ca
protein phosphatase 2, catalytic subunit, alpha isozyme
chr11_+_583142 0.80 ENSDART00000168157
mkrn2os.2
MKRN2 opposite strand, tandem duplicate 2
chr16_-_11778933 0.80 ENSDART00000184916
pafah1b3
platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit
chr15_+_29292154 0.79 ENSDART00000137817
rap1gap2a
RAP1 GTPase activating protein 2a
chr2_+_20472150 0.78 ENSDART00000168537
agla
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase a
chr16_-_39267185 0.78 ENSDART00000058550
ENSDART00000133642
gpd1l
glycerol-3-phosphate dehydrogenase 1 like
chr15_-_16070731 0.78 ENSDART00000122099
dynll2a
dynein, light chain, LC8-type 2a
chr11_+_18873113 0.76 ENSDART00000103969
ENSDART00000103968
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr9_-_22158784 0.76 ENSDART00000167850
crygm2d14
crystallin, gamma M2d14
chr5_+_32009542 0.76 ENSDART00000182025
ENSDART00000179879
scai
suppressor of cancer cell invasion
chr17_+_50074372 0.76 ENSDART00000113644
vps39
vacuolar protein sorting 39 homolog (S. cerevisiae)
chr6_+_21395051 0.76 ENSDART00000017774
cacng5a
calcium channel, voltage-dependent, gamma subunit 5a
chr10_-_32851847 0.74 ENSDART00000134255
trim37
tripartite motif containing 37
chr9_+_42095220 0.73 ENSDART00000148317
ENSDART00000134431
pcbp3
poly(rC) binding protein 3
chr10_+_36441124 0.73 ENSDART00000185626
uspl1
ubiquitin specific peptidase like 1
chr5_+_41143563 0.73 ENSDART00000011229
sub1b
SUB1 homolog, transcriptional regulator b
chr2_+_243778 0.73 ENSDART00000182262
CABZ01085887.1

chr2_+_2967255 0.72 ENSDART00000167649
ENSDART00000166449
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr17_-_30205302 0.72 ENSDART00000156827
si:dkey-27l15.1
si:dkey-27l15.1
chr4_+_4267451 0.71 ENSDART00000192069
ano2
anoctamin 2
chr10_+_5135842 0.71 ENSDART00000132627
ENSDART00000162434
zgc:113274
zgc:113274
chr20_-_34750045 0.71 ENSDART00000186130
znf395b
zinc finger protein 395b
chr14_+_14043793 0.70 ENSDART00000164376
rraga
Ras-related GTP binding A
chr17_+_27723490 0.70 ENSDART00000123588
ENSDART00000170462
ENSDART00000169708
qkia
QKI, KH domain containing, RNA binding a
chr16_-_21181128 0.70 ENSDART00000133403
pde11al
phosphodiesterase 11a, like
chr8_-_13823091 0.70 ENSDART00000177174
ENSDART00000137021
cabp4
calcium binding protein 4
chr7_-_35083585 0.69 ENSDART00000192732
agrp
agouti related neuropeptide
chr2_+_37424261 0.69 ENSDART00000132427
phc3
polyhomeotic homolog 3 (Drosophila)
chr9_-_31596016 0.68 ENSDART00000142289
nalcn
sodium leak channel, non-selective
chr23_+_20513104 0.68 ENSDART00000079591
dpm1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr19_-_41213718 0.68 ENSDART00000077121
pdk4
pyruvate dehydrogenase kinase, isozyme 4
chr16_+_22654481 0.68 ENSDART00000179762
chrnb2b
cholinergic receptor, nicotinic, beta 2b
chr14_-_38889840 0.68 ENSDART00000035779
zgc:101583
zgc:101583
chr6_-_39218609 0.67 ENSDART00000133305
os9
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr1_-_51261420 0.67 ENSDART00000168685
kif16ba
kinesin family member 16Ba
chr18_+_32615075 0.67 ENSDART00000166937
CABZ01012885.1

chr7_+_13527971 0.66 ENSDART00000020542
plekho2
pleckstrin homology domain containing, family O member 2
chr16_+_813780 0.66 ENSDART00000162474
ENSDART00000161774
irx1a
iroquois homeobox 1a
chr4_-_27129697 0.65 ENSDART00000131240
zbed4
zinc finger, BED-type containing 4
chr8_+_26292560 0.64 ENSDART00000053463
mgll
monoglyceride lipase
chr15_+_5339056 0.64 ENSDART00000174319
CABZ01018874.2

chr11_+_18873619 0.64 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr14_+_46342882 0.63 ENSDART00000193707
ENSDART00000060577
tmem33
transmembrane protein 33
chr24_-_21989406 0.63 ENSDART00000032963
apoob
apolipoprotein O, b
chr12_+_16440708 0.63 ENSDART00000113810
ankrd1b
ankyrin repeat domain 1b (cardiac muscle)
chr11_+_34522554 0.62 ENSDART00000109833
zmat3
zinc finger, matrin-type 3
chr15_-_30714130 0.62 ENSDART00000156914
ENSDART00000154714
msi2b
musashi RNA-binding protein 2b
chr21_-_21790372 0.62 ENSDART00000151094
xrra1
X-ray radiation resistance associated 1
chr7_-_40122139 0.61 ENSDART00000173982
si:ch73-174h16.5
si:ch73-174h16.5
chr6_+_36795225 0.61 ENSDART00000171504
si:ch73-29l19.1
si:ch73-29l19.1
chr5_-_17601759 0.60 ENSDART00000138387
si:ch211-130h14.6
si:ch211-130h14.6
chr10_-_5135788 0.60 ENSDART00000108587
ENSDART00000138537
sec31a
SEC31 homolog A, COPII coat complex component
chr20_+_33904258 0.60 ENSDART00000170930
rxrgb
retinoid X receptor, gamma b
chr12_-_35883814 0.59 ENSDART00000177986
ENSDART00000129888
cep131
centrosomal protein 131

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx2.2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0019557 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.8 2.4 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.7 4.8 GO:0002931 response to ischemia(GO:0002931)
0.6 1.7 GO:0051958 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.5 2.7 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.4 1.2 GO:0071435 potassium ion export(GO:0071435) potassium ion export across plasma membrane(GO:0097623)
0.4 1.2 GO:0042908 xenobiotic transport(GO:0042908)
0.4 2.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.3 1.7 GO:0006972 hyperosmotic response(GO:0006972)
0.3 1.0 GO:0002792 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.3 1.7 GO:0045056 transcytosis(GO:0045056)
0.3 2.6 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.3 1.6 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.3 1.6 GO:0070208 protein heterotrimerization(GO:0070208)
0.3 1.9 GO:0003188 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.3 0.8 GO:0010265 SCF complex assembly(GO:0010265)
0.3 1.5 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.2 0.5 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.2 1.0 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.2 1.7 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 0.7 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.2 0.9 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.2 1.4 GO:1902267 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.2 1.1 GO:0042766 nucleosome mobilization(GO:0042766)
0.2 1.7 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.2 1.9 GO:0021794 thalamus development(GO:0021794)
0.2 1.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 1.6 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.2 0.8 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.2 0.6 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.2 2.0 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 4.8 GO:0019835 cytolysis(GO:0019835)
0.2 1.0 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.2 1.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 3.5 GO:0015701 bicarbonate transport(GO:0015701)
0.2 1.5 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.1 0.9 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.4 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341) intermediate mesoderm development(GO:0048389)
0.1 0.7 GO:1990173 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1 1.5 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 0.9 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1 0.7 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.1 1.2 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 0.7 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 1.1 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.7 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.5 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.1 1.8 GO:0016486 peptide hormone processing(GO:0016486)
0.1 1.3 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.3 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.1 0.7 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.8 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.3 GO:0072196 proximal/distal pattern formation involved in nephron development(GO:0072047) distal tubule morphogenesis(GO:0072156) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.1 1.4 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 0.9 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.8 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.7 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.8 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735) negative regulation of intracellular protein transport(GO:0090317)
0.1 0.3 GO:0032801 receptor catabolic process(GO:0032801)
0.1 0.3 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.6 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.1 1.1 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 1.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.3 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.1 0.5 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.4 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.1 0.7 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 2.5 GO:0032355 response to estradiol(GO:0032355)
0.1 0.6 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.3 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.5 GO:0046070 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.1 0.4 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.9 GO:0006570 tyrosine metabolic process(GO:0006570)
0.1 0.2 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.1 0.8 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.7 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.4 GO:0007141 male meiosis I(GO:0007141)
0.1 2.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.9 GO:0032885 regulation of polysaccharide biosynthetic process(GO:0032885)
0.0 1.0 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.4 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 1.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.6 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.8 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.9 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.6 GO:0042407 cristae formation(GO:0042407)
0.0 0.6 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.4 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.5 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.7 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.6 GO:0010165 response to X-ray(GO:0010165)
0.0 0.4 GO:0006735 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 1.2 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 2.0 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.1 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.0 2.1 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.2 GO:0060465 pharynx development(GO:0060465)
0.0 0.3 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.4 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.2 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.6 GO:0086010 membrane depolarization(GO:0051899) membrane depolarization during action potential(GO:0086010)
0.0 0.9 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.1 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 1.8 GO:0007254 JNK cascade(GO:0007254)
0.0 0.2 GO:0032205 negative regulation of telomere maintenance(GO:0032205)
0.0 0.7 GO:0010675 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.5 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 4.0 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.1 GO:0008584 male gonad development(GO:0008584)
0.0 0.2 GO:0015809 arginine transport(GO:0015809)
0.0 0.2 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 0.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.5 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.3 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.6 GO:0002068 glandular epithelial cell development(GO:0002068) type B pancreatic cell development(GO:0003323)
0.0 0.6 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.7 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.3 GO:0060173 limb development(GO:0060173)
0.0 0.0 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.4 GO:0045841 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 2.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.2 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 2.2 GO:0051604 protein maturation(GO:0051604)
0.0 2.8 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.8 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.4 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0021594 rhombomere formation(GO:0021594)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 1.1 GO:0006821 chloride transport(GO:0006821)
0.0 0.6 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0006611 protein export from nucleus(GO:0006611)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 3.9 GO:0005579 membrane attack complex(GO:0005579)
0.2 1.0 GO:0042583 chromaffin granule(GO:0042583)
0.2 1.0 GO:0005883 neurofilament(GO:0005883)
0.2 1.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 1.3 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.2 0.5 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.2 1.6 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.4 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.1 1.7 GO:0031045 dense core granule(GO:0031045)
0.1 1.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.7 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.9 GO:0016586 RSC complex(GO:0016586)
0.1 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.7 GO:0016234 inclusion body(GO:0016234)
0.1 0.5 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.9 GO:0061617 MICOS complex(GO:0061617)
0.1 3.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 1.7 GO:0032590 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.1 0.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.5 GO:0001650 fibrillar center(GO:0001650) multimeric ribonuclease P complex(GO:0030681)
0.1 0.5 GO:0071914 prominosome(GO:0071914)
0.1 0.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.1 6.4 GO:0016459 myosin complex(GO:0016459)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.7 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.7 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 1.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 3.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.9 GO:0043186 P granule(GO:0043186)
0.0 0.9 GO:0036452 ESCRT complex(GO:0036452)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.6 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.5 GO:0030141 secretory granule(GO:0030141)
0.0 1.7 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.6 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.0 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.5 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 4.8 GO:0030133 transport vesicle(GO:0030133)
0.0 0.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 1.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0036126 sperm flagellum(GO:0036126) sperm part(GO:0097223)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0000795 synaptonemal complex(GO:0000795)
0.0 1.4 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 14.8 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.0 GO:0016841 ammonia-lyase activity(GO:0016841)
0.9 2.7 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.7 2.1 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.6 2.6 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.6 1.7 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.5 1.9 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.5 2.4 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.4 2.5 GO:0045735 nutrient reservoir activity(GO:0045735)
0.3 4.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.3 0.8 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.3 1.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.3 1.1 GO:0031782 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.2 1.2 GO:0016531 copper chaperone activity(GO:0016531)
0.2 2.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 1.4 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.2 1.4 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.2 1.8 GO:0001006 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.2 1.7 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 1.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 0.8 GO:0004135 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.2 0.8 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2 1.6 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 2.0 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.2 0.9 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.2 1.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 0.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.9 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 1.5 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.9 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 2.3 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.1 2.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.7 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 1.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 0.6 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.5 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.1 0.6 GO:0031769 glucagon receptor binding(GO:0031769)
0.1 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.1 1.6 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 1.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.5 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.8 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.5 GO:0016793 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.1 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.4 GO:0050699 WW domain binding(GO:0050699)
0.1 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.9 GO:2001069 glycogen binding(GO:2001069)
0.1 2.2 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.3 GO:0032183 SUMO binding(GO:0032183)
0.1 2.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 1.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.7 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.4 GO:0005113 patched binding(GO:0005113)
0.0 2.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.2 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 0.1 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.0 0.2 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 1.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 2.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.8 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 2.1 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.4 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 5.6 GO:0003774 motor activity(GO:0003774)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 3.5 GO:0015293 symporter activity(GO:0015293)
0.0 0.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.9 GO:0000049 tRNA binding(GO:0000049)
0.0 0.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 2.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.9 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.9 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 1.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 0.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 1.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.8 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 2.0 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.2 2.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 1.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 4.5 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.2 4.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 1.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 2.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.9 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 0.8 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.3 REACTOME DEFENSINS Genes involved in Defensins
0.1 1.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.5 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives