Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for nkx3.3-1

Z-value: 1.18

Motif logo

logo of

Transcription factors associated with nkx3.3-1

Gene Symbol Gene ID Gene Info
nkx3.3-1
ENSDARG00000110589 NK3 homeobox 3

Activity profile of nkx3.3-1 motif

Sorted Z-values of nkx3.3-1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_2815021 15.36 ENSDART00000020472
hpda
4-hydroxyphenylpyruvate dioxygenase a
chr7_-_23777445 12.30 ENSDART00000173527
si:ch211-200p22.4
si:ch211-200p22.4
chr2_+_51028269 11.94 ENSDART00000161254
eef1da
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr12_+_31713239 11.68 ENSDART00000122379
habp2
hyaluronan binding protein 2
chr8_-_14554785 10.79 ENSDART00000057645
qsox1
quiescin Q6 sulfhydryl oxidase 1
chr22_+_16022211 10.66 ENSDART00000062618
serpinc1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr5_+_37978501 10.59 ENSDART00000012050
apoa1a
apolipoprotein A-Ia
chr8_-_50147948 10.29 ENSDART00000149010
hp
haptoglobin
chr7_+_39446247 9.85 ENSDART00000033610
ENSDART00000099015
tnnt3b
troponin T type 3b (skeletal, fast)
chr4_-_8030583 8.85 ENSDART00000113628
si:ch211-240l19.8
si:ch211-240l19.8
chr7_+_7048245 8.76 ENSDART00000001649
actn3b
actinin alpha 3b
chr15_+_45563491 8.62 ENSDART00000191169
cldn15lb
claudin 15-like b
chr11_+_42556395 8.17 ENSDART00000039206
rps23
ribosomal protein S23
chr10_+_25726694 7.74 ENSDART00000140308
ugt5d1
UDP glucuronosyltransferase 5 family, polypeptide D1
chr4_-_14642379 7.72 ENSDART00000114977
si:ch211-127b11.1
si:ch211-127b11.1
chr22_-_26236188 7.64 ENSDART00000162640
ENSDART00000167169
ENSDART00000138595
c3b.1
complement component c3b, tandem duplicate 1
chr25_+_10547228 7.36 ENSDART00000067678
zgc:110339
zgc:110339
chr9_-_7390388 7.27 ENSDART00000132392
slc23a3
solute carrier family 23, member 3
chr25_+_28282274 7.25 ENSDART00000164502
aass
aminoadipate-semialdehyde synthase
chr19_+_30990129 7.10 ENSDART00000052169
ENSDART00000193376
sync
syncoilin, intermediate filament protein
chr3_+_29640837 7.09 ENSDART00000132298
eif3d
eukaryotic translation initiation factor 3, subunit D
chr15_-_41245962 6.88 ENSDART00000155359
smco4
single-pass membrane protein with coiled-coil domains 4
chr2_+_30948503 6.78 ENSDART00000149923
myom1a
myomesin 1a (skelemin)
chr19_+_30990815 6.52 ENSDART00000134645
sync
syncoilin, intermediate filament protein
chr5_+_13870340 6.35 ENSDART00000160690
hk2
hexokinase 2
chr14_+_17376940 6.02 ENSDART00000054590
ENSDART00000010148
spon2b
spondin 2b, extracellular matrix protein
chr12_-_3053699 5.95 ENSDART00000139721
dcxr
dicarbonyl/L-xylulose reductase
chr13_-_2215213 5.94 ENSDART00000129773
mlip
muscular LMNA-interacting protein
chr14_+_26719691 5.91 ENSDART00000078522
ENSDART00000172927
eef1g
eukaryotic translation elongation factor 1 gamma
chr4_-_14649158 5.89 ENSDART00000145737
si:dkey-183c2.4
si:dkey-183c2.4
chr24_-_26484298 5.70 ENSDART00000140647
eif5a
eukaryotic translation initiation factor 5A
chr15_-_3277635 5.59 ENSDART00000189094
slc25a15a
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr17_+_6563307 5.55 ENSDART00000156454
adgrf3a
adhesion G protein-coupled receptor F3a
chr20_+_23498255 5.50 ENSDART00000149922
palld
palladin, cytoskeletal associated protein
chr16_+_16977786 5.44 ENSDART00000043173
ENSDART00000132150
rpl18
ribosomal protein L18
chr25_+_11456696 5.44 ENSDART00000171408
AGBL1
si:ch73-141f14.1
chr5_-_12063381 5.44 ENSDART00000026749
nipsnap1
nipsnap homolog 1 (C. elegans)
chr10_+_10387328 5.43 ENSDART00000080904
sardh
sarcosine dehydrogenase
chr25_-_37284370 5.28 ENSDART00000103222
nudt7
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr23_+_25292147 5.24 ENSDART00000131486
pa2g4b
proliferation-associated 2G4, b
chr21_-_28523548 5.23 ENSDART00000077910
epdl2
ependymin-like 2
chr15_+_46606090 5.18 ENSDART00000020921
CABZ01044048.1

chr18_+_24562188 5.03 ENSDART00000099463
lysmd4
LysM, putative peptidoglycan-binding, domain containing 4
chr9_-_43073960 5.02 ENSDART00000059460
ttn.2
titin, tandem duplicate 2
chr21_+_26612777 4.96 ENSDART00000142667
esrra
estrogen-related receptor alpha
chr24_-_33308045 4.88 ENSDART00000149711
slc4a2b
solute carrier family 4 (anion exchanger), member 2b
chr19_+_43604643 4.86 ENSDART00000151168
si:ch211-199g17.9
si:ch211-199g17.9
chr15_+_17756113 4.82 ENSDART00000155197
si:ch211-213d14.2
si:ch211-213d14.2
chr22_+_38194151 4.75 ENSDART00000121965
cp
ceruloplasmin
chr15_+_5973909 4.66 ENSDART00000126886
ENSDART00000189618
igsf5b
immunoglobulin superfamily, member 5b
chr19_+_791538 4.62 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr9_-_49531762 4.61 ENSDART00000121875
xirp2b
xin actin binding repeat containing 2b
chr22_+_32228882 4.60 ENSDART00000092082
manf
mesencephalic astrocyte-derived neurotrophic factor
chr1_-_54706039 4.49 ENSDART00000083633
exosc1
exosome component 1
chr16_-_38609146 4.48 ENSDART00000144651
eif3ea
eukaryotic translation initiation factor 3, subunit E, a
chr16_+_3982590 4.40 ENSDART00000149295
zc3h12a
zinc finger CCCH-type containing 12A
chr19_-_34970312 4.39 ENSDART00000102896
ndrg1a
N-myc downstream regulated 1a
chr18_+_29156827 4.33 ENSDART00000137587
ENSDART00000135633
ppfibp2a
PTPRF interacting protein, binding protein 2a (liprin beta 2)
chr5_+_44846280 4.23 ENSDART00000084370
kank1a
KN motif and ankyrin repeat domains 1a
chr22_+_7480465 4.23 ENSDART00000034545
CELA1 (1 of many)
zgc:92745
chr25_+_10416583 4.12 ENSDART00000073907
ehf
ets homologous factor
chr22_-_36770649 4.10 ENSDART00000169442
acy1
aminoacylase 1
chr9_+_15893093 4.08 ENSDART00000099483
ENSDART00000134657
si:dkey-14o1.20
si:dkey-14o1.20
chr25_+_20091021 4.07 ENSDART00000187545
ENSDART00000053265
tnni4b.2
troponin I4b, tandem duplicate 2
chr4_-_75982054 4.01 ENSDART00000168369
si:ch211-232d10.1
si:ch211-232d10.1
chr25_-_16600811 3.87 ENSDART00000011397
cpa2
carboxypeptidase A2 (pancreatic)
chr16_+_46725087 3.87 ENSDART00000008920
rab11al
RAB11a, member RAS oncogene family, like
chr12_+_19030391 3.82 ENSDART00000153927
si:ch73-139e5.2
si:ch73-139e5.2
chr4_+_16715267 3.78 ENSDART00000143849
pkp2
plakophilin 2
chr10_+_10386435 3.76 ENSDART00000179214
ENSDART00000189799
ENSDART00000193875
sardh
sarcosine dehydrogenase
chr22_-_20376488 3.74 ENSDART00000140187
zbtb7a
zinc finger and BTB domain containing 7a
chr2_+_39618951 3.62 ENSDART00000077108
zgc:136870
zgc:136870
chr9_-_55586151 3.62 ENSDART00000181886
arsh
arylsulfatase H
chr10_+_40660772 3.51 ENSDART00000148007
taar19l
trace amine associated receptor 19l
chr18_+_19842569 3.50 ENSDART00000147470
iqch
IQ motif containing H
chr16_-_13612650 3.48 ENSDART00000080372
dbpb
D site albumin promoter binding protein b
chr21_+_5993188 3.46 ENSDART00000048399
slc4a4b
solute carrier family 4 (sodium bicarbonate cotransporter), member 4b
chr6_-_43028270 3.37 ENSDART00000149092
ENSDART00000149559
glyctk
glycerate kinase
chr21_+_21812311 3.37 ENSDART00000151253
neu3.4
sialidase 3 (membrane sialidase), tandem duplicate 4
chr20_+_826459 3.34 ENSDART00000104740
nt5e
5'-nucleotidase, ecto (CD73)
chr3_-_32912787 3.33 ENSDART00000156149
g6pcb
glucose-6-phosphatase b, catalytic subunit
chr5_-_57204352 3.31 ENSDART00000171252
ENSDART00000180727
man2a1
mannosidase, alpha, class 2A, member 1
chr24_-_25166720 3.30 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr12_+_22580579 3.28 ENSDART00000171725
ENSDART00000192290
capgb
capping protein (actin filament), gelsolin-like b
chr25_-_19666107 3.27 ENSDART00000149889
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr19_-_6840506 3.25 ENSDART00000081568
tcf19l
transcription factor 19 (SC1), like
chr1_-_58887610 3.22 ENSDART00000180647
CABZ01084501.1
microfibril-associated glycoprotein 4-like precursor
chr13_-_280827 3.16 ENSDART00000144819
slc30a6
solute carrier family 30 (zinc transporter), member 6
chr16_-_26132122 3.10 ENSDART00000157787
lipeb
lipase, hormone-sensitive b
chr20_-_7992496 3.06 ENSDART00000145521
plpp3
phospholipid phosphatase 3
chr18_+_33675664 3.05 ENSDART00000140043
si:dkey-47k20.8
si:dkey-47k20.8
chr7_-_59311165 3.01 ENSDART00000171105
m1ap
meiosis 1 associated protein
chr9_-_53666031 3.00 ENSDART00000126314
pcdh8
protocadherin 8
chr17_+_15388479 3.00 ENSDART00000052439
si:ch211-266g18.6
si:ch211-266g18.6
chr24_+_15670013 2.99 ENSDART00000185826
CU929414.1

chr5_-_23855447 2.98 ENSDART00000051541
gbgt1l3
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3
chr4_-_10835620 2.97 ENSDART00000150739
ppfibp1a
PTPRF interacting protein, binding protein 1a (liprin beta 1)
chr16_+_27444098 2.95 ENSDART00000157690
invs
inversin
chr1_+_35862550 2.93 ENSDART00000132118
si:ch211-194g2.4
si:ch211-194g2.4
chr9_-_34882516 2.93 ENSDART00000011163
asmtl
acetylserotonin O-methyltransferase-like
chr16_-_9675982 2.87 ENSDART00000113724
mal2
mal, T cell differentiation protein 2 (gene/pseudogene)
chr16_+_38240027 2.83 ENSDART00000111081
prune
prune exopolyphosphatase
chr4_-_12862087 2.83 ENSDART00000080536
hmga2
high mobility group AT-hook 2
chr9_+_8380728 2.82 ENSDART00000133501
si:ch1073-75o15.4
si:ch1073-75o15.4
chr13_-_40237121 2.82 ENSDART00000145635
loxl4
lysyl oxidase-like 4
chr10_+_40737540 2.75 ENSDART00000125577
taar19a
trace amine associated receptor 19a
chr21_-_41873065 2.74 ENSDART00000014538
endou2
endonuclease, polyU-specific 2
chr5_+_58550291 2.72 ENSDART00000184983
ENSDART00000044803
pou2f3
POU class 2 homeobox 3
chr2_-_55797318 2.72 ENSDART00000158147
calr3b
calreticulin 3b
chr25_+_2361721 2.70 ENSDART00000172905
zmp:0000000932
zmp:0000000932
chr5_-_8907819 2.65 ENSDART00000188523
adamts12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr16_-_22585289 2.65 ENSDART00000134239
ENSDART00000193959
ENSDART00000077998
si:dkey-238m4.3
cgna
si:dkey-238m4.3
cingulin a
chr6_+_3280939 2.64 ENSDART00000151359
kdm4aa
lysine (K)-specific demethylase 4A, genome duplicate a
chr21_+_5589923 2.63 ENSDART00000160885
stbd1
starch binding domain 1
chr10_+_40711286 2.62 ENSDART00000140242
si:ch211-139n6.11
si:ch211-139n6.11
chr4_-_11098539 2.60 ENSDART00000135511
si:dkey-21h14.12
si:dkey-21h14.12
chr10_-_39052264 2.57 ENSDART00000144036
igsf5a
immunoglobulin superfamily, member 5a
chr19_+_7810028 2.56 ENSDART00000081592
ENSDART00000140719
aqp10b
aquaporin 10b
chr8_+_53051701 2.55 ENSDART00000131514
nadka
NAD kinase a
chr14_-_36763302 2.53 ENSDART00000074786
ctso
cathepsin O
chr23_-_46040618 2.52 ENSDART00000161415
CABZ01080918.1

chr4_+_9467049 2.45 ENSDART00000012659
zgc:55888
zgc:55888
chr4_-_71708567 2.38 ENSDART00000182645
si:dkeyp-4f2.1
si:dkeyp-4f2.1
chr7_-_27038488 2.38 ENSDART00000052731
ENSDART00000191382
nucb2a
nucleobindin 2a
chr18_-_33093705 2.38 ENSDART00000059500
olfcd3
olfactory receptor C family, d3
chr2_-_57900430 2.38 ENSDART00000132245
ENSDART00000140060
si:dkeyp-68b7.7
si:dkeyp-68b7.7
chr12_+_17754859 2.38 ENSDART00000112119
bhlha15
basic helix-loop-helix family, member a15
chr24_-_41195068 2.36 ENSDART00000121592
acvr2ba
activin A receptor type 2Ba
chr2_+_53114476 2.35 ENSDART00000080850
ENSDART00000104187
CR384061.1

chr22_+_6323600 2.35 ENSDART00000193061
AL928685.4

chr17_+_23554932 2.31 ENSDART00000135814
pank1a
pantothenate kinase 1a
chr25_-_12635371 2.31 ENSDART00000162463
zcchc14
zinc finger, CCHC domain containing 14
chr5_-_54712159 2.28 ENSDART00000149207
ccnb1
cyclin B1
chr23_-_17003533 2.27 ENSDART00000080545
dnmt3bb.2
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr15_+_15771418 2.24 ENSDART00000153831
si:ch211-33e4.3
si:ch211-33e4.3
chr21_+_30549512 2.23 ENSDART00000132831
rab38c
RAB38c, member of RAS oncogene family
chr1_+_56779495 2.22 ENSDART00000192871
FO680692.1

chr21_+_21702623 2.21 ENSDART00000136840
or125-2
odorant receptor, family E, subfamily 125, member 2
chr17_+_48164536 2.20 ENSDART00000161750
ENSDART00000156923
plekhd1
pleckstrin homology domain containing, family D (with coiled-coil domains) member 1
chr7_+_17393794 2.20 ENSDART00000059673
nitr7b
novel immune-type receptor 7b
chr2_-_51454868 2.16 ENSDART00000172550
si:dkeyp-104b3.2
si:dkeyp-104b3.2
chr11_+_31680513 2.15 ENSDART00000139900
ENSDART00000040305
diaph3
diaphanous-related formin 3
chr1_+_55643198 2.15 ENSDART00000060693
adgre7
adhesion G protein-coupled receptor E7
chr23_+_7518294 2.15 ENSDART00000081536
hck
HCK proto-oncogene, Src family tyrosine kinase
chr23_-_26227805 2.14 ENSDART00000158082
BX927204.1

chr21_-_43094210 2.12 ENSDART00000144747
si:ch73-68b22.2
si:ch73-68b22.2
chr12_-_16990896 2.11 ENSDART00000152402
ifit12
interferon-induced protein with tetratricopeptide repeats 12
chr10_-_33343244 2.10 ENSDART00000164191
c2cd2
C2 calcium-dependent domain containing 2
chr21_+_25344374 2.10 ENSDART00000144724
or132-2
odorant receptor, family H, subfamily 132, member 2
chr3_-_34066548 2.08 ENSDART00000151302
ighv9-2
immunoglobulin heavy variable 9-2
chr18_+_33100606 2.08 ENSDART00000003907
si:ch211-229c8.13
si:ch211-229c8.13
chr18_-_28938912 2.06 ENSDART00000136201
si:ch211-174j14.2
si:ch211-174j14.2
chr1_-_10847753 2.06 ENSDART00000141052
dmd
dystrophin
chr15_+_37972671 2.04 ENSDART00000166764
si:dkey-238d18.9
si:dkey-238d18.9
chr4_+_53146060 2.04 ENSDART00000124912
si:dkey-8o9.2
si:dkey-8o9.2
chr13_+_33462232 2.04 ENSDART00000177841
zgc:136302
zgc:136302
chr5_-_24124118 2.03 ENSDART00000051550
capga
capping protein (actin filament), gelsolin-like a
chr21_-_40040178 2.02 ENSDART00000159741
BX248108.1
Danio rerio multidrug and toxin extrusion protein 1-like (mate4), mRNA.
chr5_+_37890521 2.01 ENSDART00000140207
tmprss4b
transmembrane protease, serine 4b
chr22_+_38159823 2.01 ENSDART00000104527
tm4sf18
transmembrane 4 L six family member 18
chr6_+_58622831 2.01 ENSDART00000128793
sp7
Sp7 transcription factor
chr19_+_42470396 1.95 ENSDART00000191679
si:dkey-166k12.1
si:dkey-166k12.1
chr22_-_31020690 1.93 ENSDART00000130604
ssuh2.4
ssu-2 homolog, tandem duplicate 4
chr3_+_11926030 1.93 ENSDART00000081367
dnaja3a
DnaJ (Hsp40) homolog, subfamily A, member 3A
chr3_-_61592417 1.93 ENSDART00000155082
nptx2a
neuronal pentraxin 2a
chr18_-_31423569 1.93 ENSDART00000185028
CU570893.1

chr4_+_53145525 1.93 ENSDART00000166960
si:dkey-8o9.2
si:dkey-8o9.2
chr25_+_28772632 1.92 ENSDART00000160619
slc41a2a
solute carrier family 41 (magnesium transporter), member 2a
chr8_+_31435452 1.92 ENSDART00000145282
selenop
selenoprotein P
chr22_+_19522982 1.88 ENSDART00000192428
ENSDART00000190812
si:dkey-78l4.13
si:dkey-78l4.13
chr18_+_2593756 1.87 ENSDART00000158022
p2ry2.3
purinergic receptor P2Y2, tandem duplicate 3
chr5_-_23783739 1.86 ENSDART00000139502
GBGT1 (1 of many)
si:ch211-287c22.1
chr3_-_5393909 1.86 ENSDART00000031885
si:ch73-106l15.2
si:ch73-106l15.2
chr4_+_13931578 1.85 ENSDART00000142466
pphln1
periphilin 1
chr7_-_70283372 1.84 ENSDART00000112969
adgra3
adhesion G protein-coupled receptor A3
chr4_+_71382288 1.84 ENSDART00000181926
si:ch211-76m11.8
si:ch211-76m11.8
chr10_+_35358675 1.83 ENSDART00000193263
si:dkey-259j3.5
si:dkey-259j3.5
chr17_-_2811992 1.82 ENSDART00000067543
gpr65
G protein-coupled receptor 65
chr8_+_23788981 1.82 ENSDART00000144229
si:ch211-163l21.8
si:ch211-163l21.8
chr16_-_12097558 1.77 ENSDART00000123142
pex5
peroxisomal biogenesis factor 5
chr5_-_69425224 1.76 ENSDART00000158096
FQ311924.1

chr10_-_40964739 1.71 ENSDART00000076359
npffr1l1
neuropeptide FF receptor 1 like 1
chr22_-_16755885 1.64 ENSDART00000036467
patj
PATJ, crumbs cell polarity complex component
chr7_+_12835048 1.63 ENSDART00000016465
cx36.7
connexin 36.7
chr2_+_24931677 1.62 ENSDART00000021528
agtr1a
angiotensin II receptor, type 1a
chr3_-_2091029 1.60 ENSDART00000141464
si:dkey-88j15.4
si:dkey-88j15.4
chr1_+_524388 1.60 ENSDART00000020327
mrpl16
mitochondrial ribosomal protein L16
chr10_+_40774215 1.58 ENSDART00000131493
taar19b
trace amine associated receptor 19b
chr20_-_33675676 1.58 ENSDART00000147168
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr12_-_44016898 1.58 ENSDART00000175304
si:dkey-201i2.4
si:dkey-201i2.4
chr15_+_33991928 1.57 ENSDART00000170177
vwde
von Willebrand factor D and EGF domains
chr13_-_50463938 1.57 ENSDART00000083857
ccnj
cyclin J
chr12_+_33433882 1.56 ENSDART00000185053
fasn
fatty acid synthase
chr4_-_62503772 1.55 ENSDART00000108891
si:dkey-165b20.1
si:dkey-165b20.1
chr2_+_45593783 1.52 ENSDART00000148037
fndc7rs2
fibronectin type III domain containing 7, related sequence 2
chr25_-_11016675 1.52 ENSDART00000099572
mespab
mesoderm posterior ab
chr1_-_11075403 1.51 ENSDART00000102903
ENSDART00000170290
dmd
dystrophin
chr4_-_49875682 1.51 ENSDART00000185921
si:dkey-156k2.3
si:dkey-156k2.3
chr22_+_19188809 1.50 ENSDART00000134791
ENSDART00000133682
si:dkey-21e2.8
si:dkey-21e2.8
chr7_-_17267950 1.49 ENSDART00000122171
nitr10a
novel immune-type receptor 10a

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx3.3-1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.7 GO:2000257 regulation of protein activation cascade(GO:2000257)
3.1 9.2 GO:1901052 sarcosine metabolic process(GO:1901052)
2.6 15.4 GO:0006572 tyrosine catabolic process(GO:0006572)
2.4 7.2 GO:0033512 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
2.4 7.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
2.1 10.6 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
2.0 5.9 GO:0005997 xylulose metabolic process(GO:0005997)
1.9 5.6 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
1.1 4.4 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.8 5.7 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.7 2.9 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.6 4.4 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.6 3.0 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.6 5.3 GO:0009109 coenzyme catabolic process(GO:0009109)
0.6 2.9 GO:0045056 transcytosis(GO:0045056)
0.6 3.3 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.6 3.3 GO:0006013 mannose metabolic process(GO:0006013)
0.5 3.8 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.5 1.9 GO:0070257 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.5 2.3 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.4 9.7 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.4 1.3 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.4 4.7 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.4 12.3 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.4 2.0 GO:0097094 regulation of osteoblast proliferation(GO:0033688) craniofacial suture morphogenesis(GO:0097094)
0.4 9.9 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.4 1.9 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.4 2.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 8.3 GO:0015701 bicarbonate transport(GO:0015701)
0.3 8.6 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.3 1.9 GO:0001887 selenium compound metabolic process(GO:0001887)
0.3 2.6 GO:0006833 water transport(GO:0006833)
0.3 5.0 GO:0048769 sarcomerogenesis(GO:0048769)
0.3 17.8 GO:0006414 translational elongation(GO:0006414)
0.3 3.4 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.3 4.9 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.3 2.3 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 2.0 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.2 2.9 GO:0007525 somatic muscle development(GO:0007525)
0.2 2.4 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.2 1.8 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.2 3.5 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.2 1.8 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.2 4.5 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.2 4.6 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.2 3.9 GO:0006825 copper ion transport(GO:0006825)
0.2 3.1 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 1.8 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.2 3.0 GO:0030259 lipid glycosylation(GO:0030259)
0.2 5.3 GO:0051014 actin filament severing(GO:0051014)
0.2 1.2 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.2 2.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.6 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 11.7 GO:0007596 blood coagulation(GO:0007596)
0.1 1.1 GO:0021588 cerebellum formation(GO:0021588)
0.1 4.7 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 5.0 GO:0061035 regulation of cartilage development(GO:0061035)
0.1 2.1 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 3.2 GO:0006829 zinc II ion transport(GO:0006829)
0.1 15.4 GO:0006457 protein folding(GO:0006457)
0.1 0.7 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 1.5 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 4.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 3.8 GO:0009395 phospholipid catabolic process(GO:0009395)
0.1 1.6 GO:0019229 regulation of vasoconstriction(GO:0019229)
0.1 0.3 GO:2000623 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 1.2 GO:1901381 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 1.6 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 4.2 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.1 7.5 GO:0006936 muscle contraction(GO:0006936)
0.1 3.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.9 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.1 0.7 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 1.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.8 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 3.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.8 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 3.4 GO:0051607 defense response to virus(GO:0051607)
0.0 1.6 GO:0032543 mitochondrial translation(GO:0032543)
0.0 2.4 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 3.5 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 4.9 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 2.4 GO:0035272 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 1.0 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 1.8 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 1.1 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 1.2 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.9 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 1.6 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.3 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 12.9 GO:0006412 translation(GO:0006412)
0.0 0.6 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.9 GO:0042113 B cell activation(GO:0042113)
0.0 0.4 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 1.4 GO:0010842 retina layer formation(GO:0010842)
0.0 1.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.1 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.5 GO:0032438 melanosome organization(GO:0032438)
0.0 4.1 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 2.6 GO:0006338 chromatin remodeling(GO:0006338)
0.0 4.1 GO:0006520 cellular amino acid metabolic process(GO:0006520)
0.0 1.3 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.1 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 1.0 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 2.3 GO:0009617 response to bacterium(GO:0009617)
0.0 0.5 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 1.1 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 1.1 GO:1903706 regulation of hemopoiesis(GO:1903706)
0.0 9.0 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 2.1 GO:0045087 innate immune response(GO:0045087)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 11.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.1 12.3 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.9 4.5 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.8 10.6 GO:0042627 chylomicron(GO:0042627)
0.8 2.3 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.4 7.1 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.4 4.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.3 13.9 GO:0005861 troponin complex(GO:0005861)
0.3 6.8 GO:0031430 M band(GO:0031430)
0.3 3.8 GO:0014704 intercalated disc(GO:0014704)
0.2 4.9 GO:0000795 synaptonemal complex(GO:0000795)
0.2 3.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 5.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 2.4 GO:0048179 activin receptor complex(GO:0048179)
0.2 8.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 3.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 5.9 GO:0016605 PML body(GO:0016605)
0.1 11.1 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 3.3 GO:0045180 basal cortex(GO:0045180)
0.1 0.7 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.1 11.7 GO:0005882 intermediate filament(GO:0005882)
0.1 1.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 6.8 GO:0005643 nuclear pore(GO:0005643)
0.1 4.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 4.3 GO:0005811 lipid particle(GO:0005811)
0.1 0.5 GO:0030891 VCB complex(GO:0030891)
0.1 8.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 5.7 GO:0001726 ruffle(GO:0001726)
0.1 3.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 11.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 5.0 GO:0005814 centriole(GO:0005814)
0.1 3.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 4.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 5.5 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 3.9 GO:0055037 recycling endosome(GO:0055037)
0.0 2.9 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 2.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 8.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 45.1 GO:0005615 extracellular space(GO:0005615)
0.0 1.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 4.4 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 0.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 2.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 12.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 2.9 GO:0044441 ciliary part(GO:0044441)
0.0 1.1 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 1.6 GO:0009986 cell surface(GO:0009986)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.4 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
3.6 10.8 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
2.4 7.1 GO:0098808 mRNA cap binding(GO:0098808)
2.3 9.2 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
2.1 10.6 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.5 5.9 GO:0005521 lamin binding(GO:0005521)
1.1 6.4 GO:0005536 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.9 12.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.9 9.9 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.8 3.4 GO:0008887 glycerate kinase activity(GO:0008887)
0.6 3.8 GO:0019215 intermediate filament binding(GO:0019215)
0.6 5.6 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.5 2.6 GO:2001070 starch binding(GO:2001070)
0.5 23.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.5 2.9 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.5 5.4 GO:0004046 aminoacylase activity(GO:0004046)
0.5 1.4 GO:0048030 disaccharide binding(GO:0048030)
0.4 1.6 GO:0001596 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.4 2.4 GO:0051185 coenzyme transporter activity(GO:0051185)
0.4 2.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.4 1.9 GO:0008430 selenium binding(GO:0008430)
0.4 8.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.3 2.6 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.3 4.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 3.4 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.3 7.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.2 1.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 1.8 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 3.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 3.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.2 5.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.2 1.0 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.2 1.6 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.2 2.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 2.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 5.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 2.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 3.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 2.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.2 3.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 3.3 GO:0050308 carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.1 10.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 3.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.4 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 1.6 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 0.7 GO:0035197 siRNA binding(GO:0035197)
0.1 7.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 3.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 1.9 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 3.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 5.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 7.1 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 2.0 GO:0033691 sialic acid binding(GO:0033691)
0.1 3.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 3.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.3 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.1 24.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 18.3 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 0.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 3.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.2 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 14.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 6.6 GO:0051082 unfolded protein binding(GO:0051082)
0.1 2.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 3.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 3.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.4 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 4.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.4 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 2.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 6.7 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.3 GO:0071949 FAD binding(GO:0071949)
0.0 1.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 3.8 GO:0004620 phospholipase activity(GO:0004620)
0.0 10.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.0 2.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 8.6 GO:0003779 actin binding(GO:0003779)
0.0 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 3.1 GO:0003774 motor activity(GO:0003774)
0.0 0.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 2.0 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.3 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 1.3 GO:0019955 cytokine binding(GO:0019955)
0.0 3.0 GO:0008083 growth factor activity(GO:0008083)
0.0 2.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.3 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 1.3 GO:0005126 cytokine receptor binding(GO:0005126)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 8.7 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 2.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.5 GO:0005507 copper ion binding(GO:0005507)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 11.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.3 14.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 18.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 PID AURORA A PATHWAY Aurora A signaling
0.0 1.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 10.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.7 3.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.4 4.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.3 9.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.3 15.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 4.8 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.2 2.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 7.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.2 4.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 3.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 3.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 0.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 5.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 11.4 REACTOME TRANSLATION Genes involved in Translation
0.1 2.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 1.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 2.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 6.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers