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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for nr2e3

Z-value: 1.10

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Transcription factors associated with nr2e3

Gene Symbol Gene ID Gene Info
nr2e3
ENSDARG00000045904 nuclear receptor subfamily 2, group E, member 3
nr2e3
ENSDARG00000113178 nuclear receptor subfamily 2, group E, member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2e3dr11_v1_chr25_+_22274642_222746420.179.7e-02Click!

Activity profile of nr2e3 motif

Sorted Z-values of nr2e3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_47633438 16.35 ENSDART00000139096
si:ch211-251b21.1
si:ch211-251b21.1
chr13_+_27316934 14.89 ENSDART00000164533
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr3_-_34801041 9.80 ENSDART00000103043
nsfa
N-ethylmaleimide-sensitive factor a
chr12_-_10275320 8.57 ENSDART00000170078
mpp2b
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr11_-_1024483 8.13 ENSDART00000017551
slc6a1b
solute carrier family 6 (neurotransmitter transporter), member 1b
chr3_-_28665291 7.93 ENSDART00000151670
fbxl16
F-box and leucine-rich repeat protein 16
chr24_-_29997145 7.60 ENSDART00000135094
palmdb
palmdelphin b
chr24_+_39158283 7.54 ENSDART00000053139
atp6v0cb
ATPase H+ transporting V0 subunit cb
chr14_-_21618005 7.45 ENSDART00000043162
reep2
receptor accessory protein 2
chr2_+_47582681 7.40 ENSDART00000187579
scg2b
secretogranin II (chromogranin C), b
chr6_+_38427357 7.29 ENSDART00000148678
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr10_-_7974155 6.99 ENSDART00000147368
ENSDART00000075524
osbp2
oxysterol binding protein 2
chr20_+_34913069 6.89 ENSDART00000007584
snap25a
synaptosomal-associated protein, 25a
chr13_+_27316632 6.75 ENSDART00000016121
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr20_-_31905968 6.71 ENSDART00000142806
stxbp5a
syntaxin binding protein 5a (tomosyn)
chr21_+_25643880 6.69 ENSDART00000192392
ENSDART00000145091
tmem151a
transmembrane protein 151A
chr8_+_16025554 6.43 ENSDART00000110171
elavl4
ELAV like neuron-specific RNA binding protein 4
chr3_+_15271943 6.42 ENSDART00000141752
asphd1
aspartate beta-hydroxylase domain containing 1
chr25_-_12203952 6.14 ENSDART00000158204
ENSDART00000091727
ntrk3a
neurotrophic tyrosine kinase, receptor, type 3a
chr23_+_19564392 6.06 ENSDART00000144746
atp6ap1lb
ATPase H+ transporting accessory protein 1 like b
chr6_+_38381957 5.93 ENSDART00000087300
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr8_+_31941650 5.85 ENSDART00000138217
htr1aa
5-hydroxytryptamine (serotonin) receptor 1A a
chr10_+_21776911 5.77 ENSDART00000163077
ENSDART00000186093
pcdh1g22
protocadherin 1 gamma 22
chr14_-_2202652 5.77 ENSDART00000171316
si:dkey-262j3.7
si:dkey-262j3.7
chr24_+_2519761 5.73 ENSDART00000106619
nrn1a
neuritin 1a
chr13_+_38520927 5.71 ENSDART00000137299
ENSDART00000111080
adgrb3
adhesion G protein-coupled receptor B3
chr8_+_3820134 5.67 ENSDART00000122454
citb
citron rho-interacting serine/threonine kinase b
chr24_-_24163201 5.62 ENSDART00000140170
map7d2b
MAP7 domain containing 2b
chr18_-_38087875 5.53 ENSDART00000111301
luzp2
leucine zipper protein 2
chr23_-_29502287 5.41 ENSDART00000141075
ENSDART00000053807
kif1b
kinesin family member 1B
chr22_+_34701848 5.14 ENSDART00000082066
atpv0e2
ATPase H+ transporting V0 subunit e2
chr12_-_10705916 5.03 ENSDART00000164038
FO704786.1

chr21_+_34976600 5.01 ENSDART00000191672
ENSDART00000139635
rbm11
RNA binding motif protein 11
chr14_-_2163454 5.00 ENSDART00000160123
ENSDART00000169653
pcdh2ab9
pcdh2ac
protocadherin 2 alpha b 9
protocadherin 2 alpha c
chr6_+_38427570 4.97 ENSDART00000170612
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr25_+_7670683 4.92 ENSDART00000040275
kcnj11l
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr2_-_32637592 4.85 ENSDART00000136353
si:dkeyp-73d8.8
si:dkeyp-73d8.8
chr20_-_34868814 4.61 ENSDART00000153049
stmn4
stathmin-like 4
chr13_+_16522608 4.56 ENSDART00000182838
ENSDART00000143200
kcnma1a
potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr5_+_36768674 4.44 ENSDART00000146854
mark4a
MAP/microtubule affinity-regulating kinase 4a
chr3_-_43821381 4.43 ENSDART00000166021
snn
stannin
chr8_-_23416362 4.41 ENSDART00000063005
gpr173
G protein-coupled receptor 173
chr5_-_28606916 4.40 ENSDART00000026107
ENSDART00000137717
tnc
tenascin C
chr4_-_5019113 4.39 ENSDART00000189321
ENSDART00000081990
strip2
striatin interacting protein 2
chr2_+_34767171 4.38 ENSDART00000145451
astn1
astrotactin 1
chr9_-_12034444 4.38 ENSDART00000038651
znf804a
zinc finger protein 804A
chr2_+_47582488 4.34 ENSDART00000149967
scg2b
secretogranin II (chromogranin C), b
chr1_+_32521469 4.29 ENSDART00000113818
ENSDART00000152580
nlgn4a
neuroligin 4a
chr10_+_22782522 4.26 ENSDART00000079498
ENSDART00000145558
si:ch211-237l4.6
si:ch211-237l4.6
chr9_-_3671911 4.16 ENSDART00000102900
sp5a
Sp5 transcription factor a
chr3_-_27868183 4.16 ENSDART00000185812
abat
4-aminobutyrate aminotransferase
chr20_+_19238382 4.16 ENSDART00000136757
fndc4a
fibronectin type III domain containing 4a
chr10_+_24504464 4.15 ENSDART00000141387
mtus2a
microtubule associated tumor suppressor candidate 2a
chr22_+_20208185 4.15 ENSDART00000142748
si:dkey-110c1.7
si:dkey-110c1.7
chr9_-_6661657 4.13 ENSDART00000133178
ENSDART00000113914
ENSDART00000061593
pou3f3a
POU class 3 homeobox 3a
chr5_+_58397646 4.10 ENSDART00000180759
HEPACAM
hepatic and glial cell adhesion molecule
chr16_-_9383629 4.09 ENSDART00000084264
ENSDART00000166958
adcy2a
adenylate cyclase 2a
chr9_+_17348745 4.07 ENSDART00000147488
slain1a
SLAIN motif family, member 1a
chr18_-_38088099 4.05 ENSDART00000146120
luzp2
leucine zipper protein 2
chr6_-_29143463 4.01 ENSDART00000087440
fam69ab
family with sequence similarity 69, member Ab
chr2_+_50608099 4.00 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr16_+_5774977 4.00 ENSDART00000134202
ccka
cholecystokinin a
chr10_+_34685135 3.94 ENSDART00000184999
nbeaa
neurobeachin a
chr12_+_25600685 3.93 ENSDART00000077157
six3b
SIX homeobox 3b
chr12_+_26632448 3.88 ENSDART00000185762
arhgap12b
Rho GTPase activating protein 12b
chr25_-_7686201 3.84 ENSDART00000157267
ENSDART00000155094
si:ch211-286c4.6
si:ch211-286c4.6
chr4_+_4816695 3.82 ENSDART00000136962
slc13a4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr20_-_34453623 3.82 ENSDART00000005609
kifap3a
kinesin-associated protein 3a
chr6_+_55277419 3.82 ENSDART00000083670
CABZ01041604.1

chr3_+_7617353 3.79 ENSDART00000165551
zgc:109949
zgc:109949
chr20_-_44576949 3.72 ENSDART00000148639
ubxn2a
UBX domain protein 2A
chr25_-_7925019 3.70 ENSDART00000183309
glcea
glucuronic acid epimerase a
chr8_-_50888806 3.69 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr8_+_29856013 3.69 ENSDART00000061981
ENSDART00000149610
hsd17b3
hydroxysteroid (17-beta) dehydrogenase 3
chr6_-_12314475 3.69 ENSDART00000156898
ENSDART00000157058
si:dkey-276j7.1
si:dkey-276j7.1
chr23_+_2778813 3.65 ENSDART00000142621
top1
DNA topoisomerase I
chr7_+_13418812 3.62 ENSDART00000191905
ENSDART00000091567
dagla
diacylglycerol lipase, alpha
chr6_-_13408680 3.60 ENSDART00000151566
fmnl2b
formin-like 2b
chr14_-_46617228 3.59 ENSDART00000161010
ENSDART00000171054
prom1a
prominin 1a
chr3_-_13147310 3.59 ENSDART00000160840
prkar1b
protein kinase, cAMP-dependent, regulatory, type I, beta
chr5_+_38263240 3.58 ENSDART00000051231
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr21_+_32332616 3.57 ENSDART00000154105
si:ch211-247j9.1
si:ch211-247j9.1
chr24_+_15020402 3.56 ENSDART00000148102
dok6
docking protein 6
chr16_-_12914288 3.55 ENSDART00000184221
cacng8b
calcium channel, voltage-dependent, gamma subunit 8b
chr9_+_42063906 3.53 ENSDART00000048893
pcbp3
poly(rC) binding protein 3
chr21_-_42202792 3.49 ENSDART00000124708
gabra6b
gamma-aminobutyric acid (GABA) A receptor, alpha 6b
chr6_+_39222598 3.49 ENSDART00000154991
b4galnt1b
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr19_+_15571290 3.48 ENSDART00000131134
foxo6b
forkhead box O6 b
chr18_-_7342950 3.48 ENSDART00000081356
caps2
calcyphosine 2
chr3_-_43821191 3.46 ENSDART00000186816
snn
stannin
chr19_+_42231431 3.43 ENSDART00000102698
jtb
jumping translocation breakpoint
chr14_-_43000836 3.43 ENSDART00000162714
pcdh10b
protocadherin 10b
chr10_+_7182168 3.40 ENSDART00000172766
psd3l
pleckstrin and Sec7 domain containing 3, like
chr20_-_50239406 3.40 ENSDART00000128053
tmem121ab
transmembrane protein 121Ab
chr5_+_32009080 3.40 ENSDART00000186885
scai
suppressor of cancer cell invasion
chrM_+_8894 3.36 ENSDART00000093611
mt-atp8
ATP synthase 8, mitochondrial
chr16_-_13004166 3.30 ENSDART00000133735
cacng7b
calcium channel, voltage-dependent, gamma subunit 7b
chr14_+_24215046 3.28 ENSDART00000079215
stc2a
stanniocalcin 2a
chr17_-_3986236 3.18 ENSDART00000188794
ENSDART00000160830
PLCB1
si:ch1073-140o9.2
chr9_-_31596016 3.18 ENSDART00000142289
nalcn
sodium leak channel, non-selective
chr1_-_50167792 3.16 ENSDART00000182993
BX537118.1

chr9_+_6079528 3.14 ENSDART00000142167
st6gal2a
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2a
chr10_+_15255198 3.13 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
vldlr
very low density lipoprotein receptor
chr3_+_50312422 3.11 ENSDART00000157689
gas7a
growth arrest-specific 7a
chr6_+_49021703 3.11 ENSDART00000149394
slc16a1a
solute carrier family 16 (monocarboxylate transporter), member 1a
chr14_-_2036604 3.08 ENSDART00000192446
BX005294.2

chr13_+_22659153 3.07 ENSDART00000143906
ENSDART00000140472
ENSDART00000078877
ENSDART00000182469
sncga
synuclein, gamma a
chr10_+_15255012 3.07 ENSDART00000023766
vldlr
very low density lipoprotein receptor
chr5_-_30588539 3.05 ENSDART00000086686
ENSDART00000159163
ENSDART00000142958
c2cd2l
c2cd2-like
chr9_-_35334642 3.04 ENSDART00000157195
ncam2
neural cell adhesion molecule 2
chr7_-_35710263 3.04 ENSDART00000043857
irx5a
iroquois homeobox 5a
chr23_-_17657348 3.04 ENSDART00000054736
bhlhe23
basic helix-loop-helix family, member e23
chr2_-_8017579 3.00 ENSDART00000040209
ephb3a
eph receptor B3a
chr12_+_42436328 3.00 ENSDART00000167324
ebf3a
early B cell factor 3a
chr18_-_29962234 2.99 ENSDART00000144996
si:ch73-103b9.2
si:ch73-103b9.2
chr14_+_32022272 2.99 ENSDART00000105760
zic6
zic family member 6
chr6_-_35310224 2.95 ENSDART00000148997
nos1apa
nitric oxide synthase 1 (neuronal) adaptor protein a
chr6_-_52400896 2.95 ENSDART00000187624
mmp24
matrix metallopeptidase 24
chr9_-_35557397 2.95 ENSDART00000100681
ncam2
neural cell adhesion molecule 2
chr22_-_3595439 2.94 ENSDART00000083308
ptprsa
protein tyrosine phosphatase, receptor type, s, a
chr18_-_14734678 2.94 ENSDART00000142462
tshz3a
teashirt zinc finger homeobox 3a
chr1_-_9980765 2.93 ENSDART00000142906
si:dkeyp-75b4.7
si:dkeyp-75b4.7
chr6_-_46403475 2.91 ENSDART00000154148
camk1a
calcium/calmodulin-dependent protein kinase Ia
chr9_-_4506819 2.89 ENSDART00000113975
kcnj3a
potassium inwardly-rectifying channel, subfamily J, member 3a
chr1_-_42778510 2.84 ENSDART00000190172
lrrtm1
leucine rich repeat transmembrane neuronal 1
chr8_-_14080534 2.83 ENSDART00000042867
dedd
death effector domain containing
chr8_+_14855471 2.81 ENSDART00000134775
si:dkey-21p1.3
si:dkey-21p1.3
chr2_+_45382433 2.79 ENSDART00000142251
wdr47a
WD repeat domain 47a
chr21_+_10794914 2.76 ENSDART00000084035
znf532
zinc finger protein 532
chr15_-_34213898 2.75 ENSDART00000191945
ENSDART00000186089
etv1
ets variant 1
chr7_-_34339845 2.74 ENSDART00000173816
madd
MAP-kinase activating death domain
chr12_+_15622621 2.74 ENSDART00000079784
plcd3b
phospholipase C, delta 3b
chr12_+_20667301 2.73 ENSDART00000144804
mxra7
matrix-remodelling associated 7
chr9_+_10014817 2.73 ENSDART00000132065
nxph2a
neurexophilin 2a
chr2_-_37043540 2.72 ENSDART00000131834
gng7
guanine nucleotide binding protein (G protein), gamma 7
chr14_-_30724165 2.69 ENSDART00000020936
fibpa
fibroblast growth factor (acidic) intracellular binding protein a
chr8_-_15398760 2.67 ENSDART00000162011
agbl4
ATP/GTP binding protein-like 4
chr15_+_7992906 2.66 ENSDART00000090790
cadm2b
cell adhesion molecule 2b
chr5_-_10946232 2.66 ENSDART00000163139
ENSDART00000031265
rtn4r
reticulon 4 receptor
chr9_-_40935934 2.63 ENSDART00000155604
C2orf88
Small membrane A-kinase anchor protein
chr18_-_8857137 2.60 ENSDART00000126331
prrt4
proline-rich transmembrane protein 4
chr18_+_50276653 2.59 ENSDART00000192120
si:dkey-105e17.1
si:dkey-105e17.1
chr3_+_24511959 2.53 ENSDART00000133898
dnal4a
dynein, axonemal, light chain 4a
chr19_-_27564980 2.49 ENSDART00000171967
si:dkeyp-46h3.8
si:dkeyp-46h3.8
chr19_+_37925616 2.48 ENSDART00000148348
nxph1
neurexophilin 1
chr20_-_16849306 2.47 ENSDART00000131395
ENSDART00000027582
brms1lb
breast cancer metastasis-suppressor 1-like b
chr15_-_28107502 2.47 ENSDART00000152270
ENSDART00000167129
cryba1a
crystallin, beta A1a
chr6_-_53885514 2.46 ENSDART00000173812
ENSDART00000127144
cacna2d2a
calcium channel, voltage-dependent, alpha 2/delta subunit 2a
chr8_+_7097740 2.43 ENSDART00000159670
abtb1
ankyrin repeat and BTB (POZ) domain containing 1
chr24_+_8904741 2.43 ENSDART00000140924
gnal
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr20_-_28698172 2.39 ENSDART00000190635
sipa1l1
signal-induced proliferation-associated 1 like 1
chr10_-_27009413 2.39 ENSDART00000139942
ENSDART00000146983
ENSDART00000132352
uqcc3
ubiquinol-cytochrome c reductase complex assembly factor 3
chr4_+_68476490 2.38 ENSDART00000168543
si:dkey-237g15.2
si:dkey-237g15.2
chr9_+_17982737 2.38 ENSDART00000192569
akap11
A kinase (PRKA) anchor protein 11
chr9_+_17983463 2.37 ENSDART00000182150
akap11
A kinase (PRKA) anchor protein 11
chr17_+_18117029 2.36 ENSDART00000154646
ENSDART00000179739
bcl11ba
B cell CLL/lymphoma 11Ba
chr4_+_5848229 2.34 ENSDART00000161101
ENSDART00000067357
lyrm5a
LYR motif containing 5a
chr4_+_23223881 2.33 ENSDART00000133056
ENSDART00000089126
trhde.1
thyrotropin releasing hormone degrading enzyme, tandem duplicate 1
chr22_+_4707663 2.32 ENSDART00000042194
cers4a
ceramide synthase 4a
chr8_+_13364950 2.32 ENSDART00000159760
slc5a5
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr23_+_26491931 2.31 ENSDART00000190124
ENSDART00000132905
si:ch73-206d17.1
si:ch73-206d17.1
chr1_-_54997746 2.31 ENSDART00000152666
slc25a23a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23a
chr10_+_45128375 2.30 ENSDART00000164805
camk2b2
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr11_+_14622379 2.28 ENSDART00000112589
efna2b
ephrin-A2b
chr7_-_35708450 2.27 ENSDART00000193886
irx5a
iroquois homeobox 5a
chr3_+_59851537 2.27 ENSDART00000180997
CU693479.1

chr5_-_20135679 2.27 ENSDART00000079402
usp30
ubiquitin specific peptidase 30
chr21_+_10076203 2.25 ENSDART00000190383
CABZ01043506.1

chr3_+_25503442 2.25 ENSDART00000190117
mchr1b
melanin-concentrating hormone receptor 1b
chr4_-_5018705 2.23 ENSDART00000154025
strip2
striatin interacting protein 2
chr9_+_22632126 2.23 ENSDART00000139434
etv5a
ets variant 5a
chr11_+_13071645 2.22 ENSDART00000162259
zfyve9b
zinc finger, FYVE domain containing 9b
chr12_+_26471712 2.21 ENSDART00000162115
ndel1a
nudE neurodevelopment protein 1-like 1a
chr6_-_25189739 2.20 ENSDART00000181980
lrrc8db
leucine rich repeat containing 8 VRAC subunit Db
chr18_+_11970987 2.20 ENSDART00000144111
si:dkeyp-2c8.3
si:dkeyp-2c8.3
chr23_+_21459263 2.20 ENSDART00000104209
her4.3
hairy-related 4, tandem duplicate 3
chr17_+_18117358 2.18 ENSDART00000144894
bcl11ba
B cell CLL/lymphoma 11Ba
chr1_+_22851745 2.18 ENSDART00000138235
ENSDART00000016488
gtf2e2
general transcription factor IIE, polypeptide 2, beta
chr3_+_51563695 2.17 ENSDART00000008607
ttyh2l
tweety homolog 2, like
chr22_+_31930650 2.17 ENSDART00000092090
dock3
dedicator of cytokinesis 3
chr5_-_50992690 2.16 ENSDART00000149553
ENSDART00000097460
ENSDART00000192021
hmgcra
3-hydroxy-3-methylglutaryl-CoA reductase a
chr17_-_2721336 2.16 ENSDART00000109582
ENSDART00000192691
ENSDART00000189381
spata7
spermatogenesis associated 7
chr16_-_9869056 2.15 ENSDART00000149312
ncalda
neurocalcin delta a
chr7_-_5487593 2.14 ENSDART00000136594
arhgef11
Rho guanine nucleotide exchange factor (GEF) 11
chr14_-_46213571 2.13 ENSDART00000056734
setd7
SET domain containing (lysine methyltransferase) 7
chr1_-_22851481 2.10 ENSDART00000054386
qdprb1
quinoid dihydropteridine reductase b1
chr23_+_21479958 2.10 ENSDART00000188302
ENSDART00000144320
si:dkey-1c11.1
si:dkey-1c11.1
chr4_-_8902406 2.10 ENSDART00000192962
mpped1
metallophosphoesterase domain containing 1
chr12_+_2631711 2.10 ENSDART00000114209
gdf10b
growth differentiation factor 10b
chr20_-_15132151 2.09 ENSDART00000063884
si:dkey-239i20.4
si:dkey-239i20.4
chr16_+_25068576 2.08 ENSDART00000125838
im:7147486
im:7147486
chr23_+_19202636 2.05 ENSDART00000162797
si:dkey-109j17.5
si:dkey-109j17.5
chr19_-_5812319 2.04 ENSDART00000114472
si:ch211-264f5.8
si:ch211-264f5.8
chr9_+_10014514 2.03 ENSDART00000185590
nxph2a
neurexophilin 2a
chr10_+_33902264 2.03 ENSDART00000193793
fryb
furry homolog b (Drosophila)
chr23_-_35066816 2.02 ENSDART00000168731
ENSDART00000163731
BX294434.1

chr20_+_29690901 2.02 ENSDART00000142669
mboat2b
membrane bound O-acyltransferase domain containing 2b
chr1_-_47114310 2.00 ENSDART00000144899
ENSDART00000053157
setd4
SET domain containing 4
chr7_-_46781614 1.99 ENSDART00000173891
tshz3b
teashirt zinc finger homeobox 3b
chr7_+_63325819 1.99 ENSDART00000085612
ENSDART00000161436
pcdh7b
protocadherin 7b

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2e3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.8 GO:0048211 Golgi vesicle docking(GO:0048211) anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
1.8 5.4 GO:0048917 posterior lateral line ganglion development(GO:0048917)
1.5 4.4 GO:0014814 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
1.1 5.7 GO:0016322 neuron remodeling(GO:0016322)
0.9 3.6 GO:0098921 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.8 4.2 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.7 3.7 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.7 2.8 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.7 4.1 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.6 7.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.6 3.6 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.5 5.4 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.5 5.3 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.5 4.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.5 3.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.5 1.9 GO:0006522 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.4 1.7 GO:0051876 pigment granule dispersal(GO:0051876)
0.4 2.5 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.4 2.8 GO:0006211 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857)
0.4 7.7 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.4 1.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.4 6.8 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.4 1.6 GO:0006844 acyl carnitine transport(GO:0006844)
0.4 1.2 GO:0003403 optic vesicle formation(GO:0003403)
0.4 2.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.4 1.9 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.4 3.4 GO:0021794 thalamus development(GO:0021794)
0.4 1.1 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.4 2.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.4 1.1 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.4 6.9 GO:0016082 synaptic vesicle priming(GO:0016082)
0.4 4.6 GO:0010996 response to auditory stimulus(GO:0010996)
0.3 1.0 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.3 3.7 GO:0046661 male sex differentiation(GO:0046661)
0.3 3.9 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.3 0.9 GO:0097264 self proteolysis(GO:0097264)
0.3 4.6 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.3 1.2 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.3 22.7 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.3 0.9 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.3 1.5 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.3 0.6 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.3 23.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.3 0.8 GO:0002188 translation reinitiation(GO:0002188)
0.3 3.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.3 5.8 GO:0050795 regulation of behavior(GO:0050795)
0.3 2.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.3 3.5 GO:0042407 cristae formation(GO:0042407)
0.3 0.8 GO:0021985 parturition(GO:0007567) neurohypophysis development(GO:0021985) maternal process involved in parturition(GO:0060137)
0.2 3.7 GO:0097499 protein localization to nonmotile primary cilium(GO:0097499)
0.2 4.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.2 3.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 1.6 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.2 1.4 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.2 19.1 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.2 3.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 0.9 GO:0010259 multicellular organism aging(GO:0010259) G-quadruplex DNA unwinding(GO:0044806)
0.2 0.9 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.2 4.9 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.2 3.7 GO:0006265 DNA topological change(GO:0006265)
0.2 0.9 GO:0033153 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.2 1.8 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.2 2.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.2 1.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.2 0.6 GO:0051037 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.2 0.6 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344) pronuclear migration(GO:0035046)
0.2 2.9 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.2 11.5 GO:0006414 translational elongation(GO:0006414)
0.2 0.9 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.2 2.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 12.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.2 2.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 1.9 GO:0046548 retinal rod cell development(GO:0046548)
0.2 6.7 GO:0050708 regulation of protein secretion(GO:0050708)
0.2 1.3 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.2 0.9 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.2 0.6 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.2 0.8 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.2 1.1 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.1 0.6 GO:0016038 absorption of visible light(GO:0016038)
0.1 1.0 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 3.0 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 1.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 4.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 6.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.7 GO:0046850 regulation of bone remodeling(GO:0046850)
0.1 1.2 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 3.2 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.9 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 1.3 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 3.4 GO:0098661 inorganic anion transmembrane transport(GO:0098661)
0.1 1.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 3.4 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.1 1.9 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.5 GO:0061549 sympathetic ganglion development(GO:0061549)
0.1 2.2 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.1 3.4 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 0.9 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 4.4 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.1 2.3 GO:0030316 osteoclast differentiation(GO:0030316)
0.1 4.7 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.7 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 1.9 GO:0050890 cognition(GO:0050890)
0.1 0.7 GO:2000105 positive regulation of DNA-dependent DNA replication(GO:2000105)
0.1 1.7 GO:0000266 mitochondrial fission(GO:0000266)
0.1 1.3 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 5.7 GO:0007416 synapse assembly(GO:0007416)
0.1 0.3 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 1.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.5 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 4.6 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 4.2 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.8 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 0.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 1.1 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 0.3 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 1.5 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 1.9 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 1.7 GO:0060324 face development(GO:0060324)
0.1 5.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 0.9 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 17.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 4.3 GO:0048332 mesoderm morphogenesis(GO:0048332)
0.1 7.2 GO:0008360 regulation of cell shape(GO:0008360)
0.1 0.5 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 2.4 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.1 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.8 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.1 13.0 GO:0006814 sodium ion transport(GO:0006814)
0.1 0.7 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 2.2 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 0.4 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 2.4 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 2.1 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.9 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.7 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 2.6 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase II promoter(GO:0042795) snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 1.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 0.2 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 1.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 3.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 1.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 1.2 GO:0035775 pronephric glomerulus morphogenesis(GO:0035775) glomerulus morphogenesis(GO:0072102)
0.1 1.0 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.1 0.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 1.4 GO:0009648 photoperiodism(GO:0009648)
0.1 0.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.3 GO:0042766 nucleosome mobilization(GO:0042766)
0.1 1.0 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 0.4 GO:0060114 reflex(GO:0060004) vestibular reflex(GO:0060005) vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.1 1.1 GO:0046058 cAMP metabolic process(GO:0046058)
0.1 0.8 GO:1900151 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 2.0 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 2.2 GO:0007586 digestion(GO:0007586)
0.0 0.1 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
0.0 0.8 GO:0007340 acrosome reaction(GO:0007340)
0.0 1.2 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 1.7 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.0 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 2.3 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.6 GO:0007634 optokinetic behavior(GO:0007634)
0.0 4.3 GO:0001666 response to hypoxia(GO:0001666)
0.0 2.3 GO:0006821 chloride transport(GO:0006821)
0.0 3.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 10.6 GO:0006869 lipid transport(GO:0006869)
0.0 1.8 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.9 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 3.0 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.3 GO:0006505 GPI anchor metabolic process(GO:0006505)
0.0 3.0 GO:0021510 spinal cord development(GO:0021510)
0.0 1.3 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.9 GO:0043486 histone exchange(GO:0043486)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 4.4 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 1.0 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.7 GO:0046834 lipid phosphorylation(GO:0046834) phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 3.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.8 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.7 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.2 GO:0043113 receptor clustering(GO:0043113)
0.0 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 1.2 GO:0007605 sensory perception of sound(GO:0007605)
0.0 2.8 GO:0044782 cilium organization(GO:0044782)
0.0 0.1 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.7 GO:0071711 basement membrane organization(GO:0071711)
0.0 1.7 GO:0021782 glial cell development(GO:0021782)
0.0 0.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 5.2 GO:0008380 RNA splicing(GO:0008380)
0.0 0.1 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.5 GO:0006826 iron ion transport(GO:0006826)
0.0 1.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.7 GO:0003341 cilium movement(GO:0003341)
0.0 4.2 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.0 GO:2000623 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 1.2 GO:0002521 leukocyte differentiation(GO:0002521)
0.0 4.1 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 5.0 GO:0007420 brain development(GO:0007420)
0.0 0.5 GO:0003333 amino acid transmembrane transport(GO:0003333) organic acid transmembrane transport(GO:1903825) carboxylic acid transmembrane transport(GO:1905039)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 16.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
1.1 6.9 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
1.0 6.1 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
1.0 5.7 GO:0043083 synaptic cleft(GO:0043083)
0.9 12.7 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.6 21.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.6 7.4 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.6 2.8 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.5 7.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.4 3.6 GO:0071914 prominosome(GO:0071914)
0.4 6.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.4 3.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 3.5 GO:0061617 MICOS complex(GO:0061617)
0.3 3.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.3 1.4 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.2 4.6 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.2 0.9 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.2 0.8 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.2 2.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 0.6 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.2 1.4 GO:0035253 ciliary rootlet(GO:0035253)
0.2 7.2 GO:0043679 axon terminus(GO:0043679)
0.2 0.8 GO:0070743 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.2 0.6 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.2 2.6 GO:0030056 hemidesmosome(GO:0030056)
0.2 2.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 6.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 13.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 6.4 GO:0043204 perikaryon(GO:0043204)
0.1 7.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.3 GO:0032021 NELF complex(GO:0032021)
0.1 9.1 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.4 GO:0005688 U6 snRNP(GO:0005688)
0.1 11.4 GO:0005871 kinesin complex(GO:0005871)
0.1 3.9 GO:0034707 chloride channel complex(GO:0034707)
0.1 11.7 GO:0030141 secretory granule(GO:0030141)
0.1 1.8 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.9 GO:0031931 TORC1 complex(GO:0031931)
0.1 5.3 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.4 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.9 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.9 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.3 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.1 2.3 GO:0030286 dynein complex(GO:0030286)
0.1 1.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 5.8 GO:0031201 SNARE complex(GO:0031201)
0.1 4.3 GO:0030496 midbody(GO:0030496)
0.1 0.5 GO:0000938 GARP complex(GO:0000938)
0.1 3.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 19.2 GO:0030424 axon(GO:0030424)
0.1 1.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.4 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 1.4 GO:0046930 pore complex(GO:0046930)
0.1 5.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 11.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 7.2 GO:0005795 Golgi stack(GO:0005795)
0.1 7.6 GO:0005741 mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.1 13.1 GO:0030425 dendrite(GO:0030425)
0.1 1.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.8 GO:0030427 site of polarized growth(GO:0030427)
0.1 1.4 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.5 GO:0034464 BBSome(GO:0034464)
0.1 1.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 2.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0031256 leading edge membrane(GO:0031256)
0.0 0.8 GO:0038201 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.0 0.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 2.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.6 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 2.9 GO:0005930 axoneme(GO:0005930)
0.0 8.7 GO:0043005 neuron projection(GO:0043005)
0.0 1.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.5 GO:1990246 uniplex complex(GO:1990246)
0.0 1.0 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.2 GO:0001726 ruffle(GO:0001726)
0.0 1.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.9 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.3 GO:0097346 INO80-type complex(GO:0097346)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.7 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 21.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 2.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 3.4 GO:0019866 organelle inner membrane(GO:0019866)
0.0 0.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.8 GO:0055037 recycling endosome(GO:0055037)
0.0 0.9 GO:0005925 focal adhesion(GO:0005925)
0.0 0.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 4.0 GO:0005730 nucleolus(GO:0005730)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.5 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0097546 ciliary base(GO:0097546)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 16.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.5 6.2 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
1.0 3.1 GO:1903136 cuprous ion binding(GO:1903136)
1.0 6.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.9 3.7 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.8 2.4 GO:1901612 cardiolipin binding(GO:1901612)
0.8 4.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.8 2.3 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)
0.6 21.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.6 8.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.5 1.6 GO:0008517 folic acid transporter activity(GO:0008517)
0.5 3.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.5 21.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.5 1.9 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.5 1.4 GO:0048030 disaccharide binding(GO:0048030)
0.5 1.4 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.4 2.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.4 1.6 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.4 6.7 GO:0045159 myosin II binding(GO:0045159)
0.4 3.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.4 1.9 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.3 3.7 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.3 3.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.3 2.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 1.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.3 0.9 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.3 7.7 GO:0015248 sterol transporter activity(GO:0015248)
0.3 3.7 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.3 11.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 7.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.3 4.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.3 1.0 GO:0070699 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.3 2.9 GO:0035804 structural constituent of egg coat(GO:0035804)
0.3 3.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 1.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 0.8 GO:0004990 oxytocin receptor activity(GO:0004990)
0.2 1.2 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.2 2.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 3.6 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.2 1.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.2 5.4 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 1.4 GO:0035173 histone kinase activity(GO:0035173)
0.2 1.4 GO:0070888 E-box binding(GO:0070888)
0.2 1.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 0.6 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 1.8 GO:0016933 inhibitory extracellular ligand-gated ion channel activity(GO:0005237) extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 0.8 GO:0019972 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.2 0.6 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.2 2.6 GO:0030506 ankyrin binding(GO:0030506)
0.2 1.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 0.9 GO:0034046 poly(G) binding(GO:0034046)
0.2 3.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 3.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 1.2 GO:0030274 LIM domain binding(GO:0030274)
0.2 2.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 5.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 1.0 GO:0004960 thromboxane receptor activity(GO:0004960)
0.2 5.3 GO:0051018 protein kinase A binding(GO:0051018)
0.2 0.6 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.2 1.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 1.9 GO:0042285 xylosyltransferase activity(GO:0042285)
0.2 2.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 0.8 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2 4.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 3.2 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.1 5.1 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 11.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 2.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 2.0 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.8 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 6.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.4 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 1.5 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 3.7 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.5 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 0.9 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.1 2.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.5 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 1.6 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.4 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 2.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.3 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.9 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 9.7 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 4.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 3.4 GO:0015370 solute:sodium symporter activity(GO:0015370)
0.1 0.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 2.5 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.1 1.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.9 GO:0005042 netrin receptor activity(GO:0005042)
0.1 3.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 1.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.2 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 2.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 1.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.4 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 1.1 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 1.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 4.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.9 GO:2001069 glycogen binding(GO:2001069)
0.1 0.4 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.5 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 2.0 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.0 GO:0070122 isopeptidase activity(GO:0070122)
0.1 1.6 GO:0008483 transaminase activity(GO:0008483)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 2.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 2.0 GO:0005518 collagen binding(GO:0005518)
0.1 0.3 GO:0030060 malate dehydrogenase activity(GO:0016615) L-malate dehydrogenase activity(GO:0030060)
0.1 3.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 2.3 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 2.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.1 GO:0009931 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.6 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0031628 opioid receptor binding(GO:0031628)
0.0 2.2 GO:0050661 NADP binding(GO:0050661)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 5.3 GO:0051213 dioxygenase activity(GO:0051213)
0.0 2.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.3 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.6 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 11.5 GO:0008017 microtubule binding(GO:0008017)
0.0 2.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 2.6 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 2.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0009055 electron carrier activity(GO:0009055)
0.0 1.0 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.8 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 5.5 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 2.7 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.2 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.3 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.5 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.9 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 4.6 GO:0003682 chromatin binding(GO:0003682)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.1 GO:0015297 antiporter activity(GO:0015297)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 32.1 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.4 7.6 PID REELIN PATHWAY Reelin signaling pathway
0.3 4.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 3.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.2 4.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 2.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 4.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 3.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 2.9 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 6.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.8 ST GA12 PATHWAY G alpha 12 Pathway
0.1 1.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.8 ST GA13 PATHWAY G alpha 13 Pathway
0.0 2.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 18.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.9 3.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.6 9.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.5 4.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.4 3.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 4.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 5.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.3 1.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 2.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 1.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 1.0 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 1.8 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.2 1.7 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.2 4.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.9 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.8 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 1.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 0.5 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 1.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 1.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.9 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 1.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.1 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.8 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis