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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for nr2f1a

Z-value: 1.92

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Transcription factors associated with nr2f1a

Gene Symbol Gene ID Gene Info
nr2f1a
ENSDARG00000052695 nuclear receptor subfamily 2, group F, member 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2f1adr11_v1_chr5_+_49744713_49744713-0.094.0e-01Click!

Activity profile of nr2f1a motif

Sorted Z-values of nr2f1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_23913943 38.28 ENSDART00000175404
ENSDART00000129525
apoa4b.1
apolipoprotein A-IV b, tandem duplicate 1
chr23_+_42454292 37.24 ENSDART00000171459
cyp2aa2
y cytochrome P450, family 2, subfamily AA, polypeptide 2
chr15_-_16884912 33.96 ENSDART00000062135
zgc:103681
zgc:103681
chr7_+_52122224 32.84 ENSDART00000174268
cyp2x12
cytochrome P450, family 2, subfamily X, polypeptide 12
chr17_-_30702411 31.30 ENSDART00000114358
zgc:194392
zgc:194392
chr15_-_21239416 30.85 ENSDART00000155787
A2ML1 (1 of many)
si:dkey-105h12.2
chr16_-_45917322 30.50 ENSDART00000060822
afp4
antifreeze protein type IV
chr15_+_28202170 30.23 ENSDART00000077736
vtna
vitronectin a
chr2_-_42234484 29.13 ENSDART00000132617
ENSDART00000136690
ENSDART00000141358
apom
apolipoprotein M
chr24_-_2843107 28.49 ENSDART00000165290
cyb5a
cytochrome b5 type A (microsomal)
chr11_-_8167799 27.24 ENSDART00000133574
ENSDART00000024046
ENSDART00000146940
uox
urate oxidase
chr3_+_12816362 27.11 ENSDART00000163743
ENSDART00000170788
cyp2k6
cytochrome P450, family 2, subfamily K, polypeptide 6
chr19_+_9277327 26.36 ENSDART00000104623
ENSDART00000151164
si:rp71-15k1.1
si:rp71-15k1.1
chr20_+_31269778 24.69 ENSDART00000133353
apobb.1
apolipoprotein Bb, tandem duplicate 1
chr17_+_30704068 24.02 ENSDART00000062793
apoba
apolipoprotein Ba
chr7_+_52135791 23.99 ENSDART00000098705
cyp2x12
cytochrome P450, family 2, subfamily X, polypeptide 12
chr8_+_30709685 22.55 ENSDART00000133989
upb1
ureidopropionase, beta
chr10_+_26747755 21.92 ENSDART00000100329
f9b
coagulation factor IXb
chr5_-_69934558 21.20 ENSDART00000124954
ugt2a4
UDP glucuronosyltransferase 2 family, polypeptide A4
chr17_-_15149192 20.27 ENSDART00000180511
ENSDART00000103405
gch1
GTP cyclohydrolase 1
chr3_-_45848257 19.47 ENSDART00000147198
igfals
insulin-like growth factor binding protein, acid labile subunit
chr18_+_31016379 19.46 ENSDART00000172461
ENSDART00000163471
uraha
urate (5-hydroxyiso-) hydrolase a
chr22_-_24818066 19.16 ENSDART00000143443
vtg6
vitellogenin 6
chr9_+_38292947 19.15 ENSDART00000146663
tfcp2l1
transcription factor CP2-like 1
chr20_+_43925266 19.13 ENSDART00000037379
clic5b
chloride intracellular channel 5b
chr10_-_32524771 19.03 ENSDART00000066793
dgat2
diacylglycerol O-acyltransferase 2
chr15_+_21202820 19.00 ENSDART00000154036
si:dkey-52d15.2
si:dkey-52d15.2
chr22_-_23668356 18.95 ENSDART00000167106
ENSDART00000159622
ENSDART00000163228
cfh
complement factor H
chr1_-_9249943 18.82 ENSDART00000055011
zgc:136472
zgc:136472
chr11_+_3585934 18.76 ENSDART00000055694
cdab
cytidine deaminase b
chr18_+_40462445 18.75 ENSDART00000087645
ugt5c2
UDP glucuronosyltransferase 5 family, polypeptide C2
chr22_-_20126230 17.84 ENSDART00000138688
creb3l3a
cAMP responsive element binding protein 3-like 3a
chr16_+_26012569 17.56 ENSDART00000148846
prss59.1
protease, serine, 59, tandem duplicate 1
chr22_-_17595310 17.37 ENSDART00000099056
gpx4a
glutathione peroxidase 4a
chr8_-_50482781 17.12 ENSDART00000056361
ido1
indoleamine 2,3-dioxygenase 1
chr12_-_3940768 17.02 ENSDART00000134292
zgc:92040
zgc:92040
chr6_+_60055168 16.54 ENSDART00000008752
pck1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr12_-_6172154 16.40 ENSDART00000185434
a1cf
apobec1 complementation factor
chr19_-_3303995 16.13 ENSDART00000105150
si:ch211-133n4.9
si:ch211-133n4.9
chr2_+_37875789 16.02 ENSDART00000036318
ENSDART00000127679
cbln13
cerebellin 13
chr13_-_22843562 15.70 ENSDART00000142738
pbld
phenazine biosynthesis like protein domain containing
chr21_+_38002879 15.52 ENSDART00000065183
cldn2
claudin 2
chr25_-_26018240 15.41 ENSDART00000150800
acsbg1
acyl-CoA synthetase bubblegum family member 1
chr23_-_27701361 15.36 ENSDART00000186688
ENSDART00000183985
dnajc22
DnaJ (Hsp40) homolog, subfamily C, member 22
chr23_+_25856541 15.32 ENSDART00000145426
ENSDART00000028236
hnf4a
hepatocyte nuclear factor 4, alpha
chr21_+_25221940 15.12 ENSDART00000108972
sycn.1
syncollin, tandem duplicate 1
chr9_-_48736388 14.97 ENSDART00000022074
dhrs9
dehydrogenase/reductase (SDR family) member 9
chr7_+_25036188 13.75 ENSDART00000163957
ENSDART00000169749
sb:cb1058
sb:cb1058
chr16_+_26774182 13.21 ENSDART00000042895
cdh17
cadherin 17, LI cadherin (liver-intestine)
chr25_-_30429607 13.16 ENSDART00000162429
ENSDART00000176535
si:ch211-93f2.1
si:ch211-93f2.1
chr18_+_17611627 13.15 ENSDART00000046891
cetp
cholesteryl ester transfer protein, plasma
chr5_+_57328535 12.92 ENSDART00000149646
slc31a1
solute carrier family 31 (copper transporter), member 1
chr15_-_37875601 12.51 ENSDART00000122439
si:dkey-238d18.4
si:dkey-238d18.4
chr13_-_12581388 12.34 ENSDART00000079655
enpep
glutamyl aminopeptidase
chr21_+_25226558 12.23 ENSDART00000168480
sycn.2
syncollin, tandem duplicate 2
chr23_-_24488696 12.16 ENSDART00000155593
tmem82
transmembrane protein 82
chr16_-_24668620 12.00 ENSDART00000012807
pon3.2
paraoxonase 3, tandem duplicate 2
chr5_-_3839285 11.99 ENSDART00000122292
mlxipl
MLX interacting protein like
chr17_-_49407091 11.73 ENSDART00000021950
mthfd1b
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr25_-_20049449 11.48 ENSDART00000104315
zgc:136858
zgc:136858
chr7_+_35068036 11.48 ENSDART00000022139
zgc:136461
zgc:136461
chr6_-_53204808 11.22 ENSDART00000160955
slc38a3b
solute carrier family 38, member 3b
chr5_-_56412262 10.98 ENSDART00000083079
acaca
acetyl-CoA carboxylase alpha
chr7_+_13988075 10.71 ENSDART00000186812
furina
furin (paired basic amino acid cleaving enzyme) a
chr19_-_27564458 10.50 ENSDART00000123155
si:dkeyp-46h3.6
si:dkeyp-46h3.6
chr17_+_48314724 10.03 ENSDART00000125617
smoc1
SPARC related modular calcium binding 1
chr10_-_322769 10.00 ENSDART00000165244
akt2l
v-akt murine thymoma viral oncogene homolog 2, like
chr24_+_20325312 9.81 ENSDART00000007997
acaa1
acetyl-CoA acyltransferase 1
chr20_+_25575391 9.77 ENSDART00000063108
cyp2p8
cytochrome P450, family 2, subfamily P, polypeptide 8
chr3_+_12710350 9.73 ENSDART00000157959
cyp2k18
cytochrome P450, family 2, subfamily K, polypeptide 18
chr14_+_32926385 9.63 ENSDART00000139159
lnx2b
ligand of numb-protein X 2b
chr3_+_18795570 9.33 ENSDART00000042368
fahd1
fumarylacetoacetate hydrolase domain containing 1
chr12_-_5120339 9.30 ENSDART00000168759
rbp4
retinol binding protein 4, plasma
chr7_+_14005111 9.28 ENSDART00000187365
furina
furin (paired basic amino acid cleaving enzyme) a
chr3_+_7771420 9.23 ENSDART00000156809
ENSDART00000156309
hook2
hook microtubule-tethering protein 2
chr10_-_21542702 8.95 ENSDART00000146761
ENSDART00000134502
zgc:165539
zgc:165539
chr6_-_1768724 8.50 ENSDART00000162488
ENSDART00000163613
zgc:158417
zgc:158417
chr18_-_15771551 8.49 ENSDART00000130931
ENSDART00000154079
si:ch211-219a15.3
si:ch211-219a15.3
chr12_-_5120175 8.49 ENSDART00000160729
rbp4
retinol binding protein 4, plasma
chr8_+_39802506 8.48 ENSDART00000018862
hnf1a
HNF1 homeobox a
chr21_+_6114305 8.46 ENSDART00000141607
fpgs
folylpolyglutamate synthase
chr19_-_27570333 8.41 ENSDART00000146562
ENSDART00000179060
si:dkeyp-46h3.5
si:dkeyp-46h3.8
si:dkeyp-46h3.5
si:dkeyp-46h3.8
chr9_+_21151138 8.34 ENSDART00000133903
hao2
hydroxyacid oxidase 2 (long chain)
chr1_-_28749604 8.31 ENSDART00000148522
GK3P
zgc:172295
chr3_+_12744083 8.31 ENSDART00000158554
ENSDART00000169545
cyp2k21
cytochrome P450, family 2, subfamily k, polypeptide 21
chr17_-_2573021 8.29 ENSDART00000074181
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr3_-_3448095 8.27 ENSDART00000078886
A2ML1 (1 of many)
si:dkey-46g23.5
chr18_+_44769027 8.24 ENSDART00000145190
ilvbl
ilvB (bacterial acetolactate synthase)-like
chr22_-_14262115 8.08 ENSDART00000168264
si:ch211-246m6.5
si:ch211-246m6.5
chr1_-_9644630 7.87 ENSDART00000123725
ENSDART00000161164
ugt5b3
UDP glucuronosyltransferase 5 family, polypeptide B3
chr8_-_38810233 7.69 ENSDART00000085304
pcsk5b
proprotein convertase subtilisin/kexin type 5b
chr14_+_36246726 7.59 ENSDART00000105602
elovl6
ELOVL fatty acid elongase 6
chr18_+_44768829 7.57 ENSDART00000016271
ilvbl
ilvB (bacterial acetolactate synthase)-like
chr3_-_49925313 7.55 ENSDART00000164361
gcgra
glucagon receptor a
chr21_+_5589923 7.42 ENSDART00000160885
stbd1
starch binding domain 1
chr17_-_2590222 7.34 ENSDART00000185711
CR759892.1

chr1_+_24387659 7.33 ENSDART00000130356
qdprb2
quinoid dihydropteridine reductase b2
chr16_-_17200120 7.33 ENSDART00000147739
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr12_-_31457301 7.23 ENSDART00000043887
ENSDART00000148603
acsl5
acyl-CoA synthetase long chain family member 5
chr15_+_17030941 7.14 ENSDART00000062069
plin2
perilipin 2
chr23_+_42434348 7.09 ENSDART00000161027
cyp2aa1
cytochrome P450, family 2, subfamily AA, polypeptide 1
chr3_+_3454610 7.08 ENSDART00000024900
zgc:165453
zgc:165453
chr7_-_28549361 7.05 ENSDART00000173918
ENSDART00000054368
ENSDART00000113313
st5
suppression of tumorigenicity 5
chr10_+_19569052 7.05 ENSDART00000058425
CABZ01059627.1

chr21_+_15713097 6.95 ENSDART00000015841
gstt1b
glutathione S-transferase theta 1b
chr13_-_9335891 6.90 ENSDART00000080637
BX901922.1

chr4_-_5597167 6.89 ENSDART00000132431
vegfab
vascular endothelial growth factor Ab
chr19_-_8798178 6.82 ENSDART00000188232
cers2a
ceramide synthase 2a
chr15_+_17031111 6.72 ENSDART00000175378
plin2
perilipin 2
chr6_+_154556 6.70 ENSDART00000193153
zglp1
zinc finger, GATA-like protein 1
chr15_+_17030473 6.67 ENSDART00000129407
plin2
perilipin 2
chr1_-_56435182 6.59 ENSDART00000037576
slc25a10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr17_-_2578026 6.54 ENSDART00000065821
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr2_+_52065884 6.50 ENSDART00000146418
shda
Src homology 2 domain containing transforming protein D, a
chr17_+_12408405 6.50 ENSDART00000154827
ENSDART00000048440
ENSDART00000156429
khk
ketohexokinase
chr17_-_25737452 6.49 ENSDART00000152021
si:ch211-214p16.3
si:ch211-214p16.3
chr17_+_15213496 6.46 ENSDART00000058351
ENSDART00000131663
gnpnat1
glucosamine-phosphate N-acetyltransferase 1
chr17_-_2595736 6.42 ENSDART00000128797
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr5_+_69868911 6.37 ENSDART00000014649
ENSDART00000188215
ENSDART00000167385
ugt2a5
UDP glucuronosyltransferase 2 family, polypeptide A5
chr5_-_20205075 6.34 ENSDART00000051611
dao.3
D-amino-acid oxidase, tandem duplicate 3
chr8_+_15254564 6.32 ENSDART00000024433
slc5a9
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr15_-_6946286 6.30 ENSDART00000019330
ech1
enoyl CoA hydratase 1, peroxisomal
chr11_+_18037729 6.30 ENSDART00000111624
zgc:175135
zgc:175135
chr19_+_31532043 6.29 ENSDART00000136289
tmem64
transmembrane protein 64
chr19_+_4912817 6.24 ENSDART00000101658
ENSDART00000165082
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr2_-_57076687 6.23 ENSDART00000161523
slc25a42
solute carrier family 25, member 42
chr14_-_14659023 6.23 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
nsdhl
NAD(P) dependent steroid dehydrogenase-like
chr11_+_18053333 6.15 ENSDART00000075750
zgc:175135
zgc:175135
chr8_-_2529878 6.12 ENSDART00000056767
acaa2
acetyl-CoA acyltransferase 2
chr25_-_37284370 6.03 ENSDART00000103222
nudt7
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr5_-_36549024 6.02 ENSDART00000097671
zgc:158432
zgc:158432
chr23_-_33753361 5.95 ENSDART00000025196
bin2a
bridging integrator 2a
chr11_-_40647190 5.84 ENSDART00000173217
ENSDART00000173276
ENSDART00000147264
fam213b
family with sequence similarity 213, member B
chr3_-_18189283 5.84 ENSDART00000049240
tob1a
transducer of ERBB2, 1a
chr25_-_25384045 5.70 ENSDART00000150631
zgc:123278
zgc:123278
chr24_-_26820698 5.67 ENSDART00000147788
fndc3bb
fibronectin type III domain containing 3Bb
chr20_+_2281933 5.67 ENSDART00000137579
si:ch73-18b11.2
si:ch73-18b11.2
chr6_+_27624023 5.66 ENSDART00000147789
slco2a1
solute carrier organic anion transporter family, member 2A1
chr6_-_39344259 5.63 ENSDART00000104074
zgc:158846
zgc:158846
chr7_+_49681040 5.61 ENSDART00000176372
ENSDART00000192172
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr1_-_50838160 5.61 ENSDART00000163939
ENSDART00000165111
zgc:154142
zgc:154142
chr3_-_3496738 5.60 ENSDART00000186849
CABZ01040998.1

chr19_+_19652439 5.56 ENSDART00000165934
hibadha
3-hydroxyisobutyrate dehydrogenase a
chr24_-_26369185 5.53 ENSDART00000080039
lrrc31
leucine rich repeat containing 31
chr2_-_24407933 5.52 ENSDART00000088584
si:dkey-208k22.6
si:dkey-208k22.6
chr8_-_23780334 5.51 ENSDART00000145179
ENSDART00000145894
zgc:195245
zgc:195245
chr11_+_18157260 5.43 ENSDART00000144659
zgc:173545
zgc:173545
chr6_+_54248705 5.43 ENSDART00000162469
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr7_+_34297271 5.39 ENSDART00000180342
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr7_-_38792543 5.39 ENSDART00000157416
si:dkey-23n7.10
si:dkey-23n7.10
chr8_-_8698607 5.36 ENSDART00000046712
zgc:86609
zgc:86609
chr16_-_45327616 5.35 ENSDART00000158733
si:dkey-33i11.1
si:dkey-33i11.1
chr11_+_18130300 5.34 ENSDART00000169146
zgc:175135
zgc:175135
chr5_-_69180587 5.31 ENSDART00000156681
ENSDART00000160753
zgc:171967
zgc:171967
chr11_-_34147205 5.25 ENSDART00000173216
atp13a3
ATPase 13A3
chr20_-_36809059 5.15 ENSDART00000062925
slc25a27
solute carrier family 25, member 27
chr3_+_31662126 5.14 ENSDART00000113441
mylk5
myosin, light chain kinase 5
chr7_+_34296789 5.08 ENSDART00000052471
ENSDART00000173798
ENSDART00000173778
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr7_-_24520866 5.03 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr17_-_6613458 5.00 ENSDART00000175024
si:ch211-189e2.3
si:ch211-189e2.3
chr3_+_46764022 4.99 ENSDART00000023814
prkcsh
protein kinase C substrate 80K-H
chr12_+_27156943 4.99 ENSDART00000153030
ENSDART00000001737
skap1
src kinase associated phosphoprotein 1
chr17_+_6538733 4.98 ENSDART00000193712
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr25_+_18587338 4.98 ENSDART00000180287
met
MET proto-oncogene, receptor tyrosine kinase
chr2_+_52232630 4.91 ENSDART00000006216
plpp2a
phospholipid phosphatase 2a
chr8_-_22542467 4.91 ENSDART00000182588
ENSDART00000134542
csde1
cold shock domain containing E1, RNA-binding
chr11_+_30296332 4.89 ENSDART00000192843
ugt1b7
UDP glucuronosyltransferase 1 family, polypeptide B7
chr14_-_7409364 4.87 ENSDART00000036463
dnd1
DND microRNA-mediated repression inhibitor 1
chr9_-_38036984 4.83 ENSDART00000134574
hacd2
3-hydroxyacyl-CoA dehydratase 2
chr24_-_7587401 4.82 ENSDART00000093163
galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr16_+_32029090 4.79 ENSDART00000041054
tmc4
transmembrane channel-like 4
chr14_+_3287740 4.77 ENSDART00000186290
cdx1a
caudal type homeobox 1a
chr24_-_30275204 4.71 ENSDART00000164187
snx7
sorting nexin 7
chr11_-_45141309 4.71 ENSDART00000181736
cant1b
calcium activated nucleotidase 1b
chr10_-_21362071 4.68 ENSDART00000125167
avd
avidin
chr23_+_9522942 4.68 ENSDART00000137751
osbpl2b
oxysterol binding protein-like 2b
chr15_+_20403903 4.64 ENSDART00000134182
cox7a1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr24_+_26887487 4.64 ENSDART00000189425
CR376848.1

chr25_+_6266009 4.60 ENSDART00000148995
slc25a44a
solute carrier family 25, member 44 a
chr14_-_48103207 4.55 ENSDART00000056712
etfdh
electron-transferring-flavoprotein dehydrogenase
chr4_-_20156085 4.52 ENSDART00000055317
lrrc17
leucine rich repeat containing 17
chr17_+_12408188 4.52 ENSDART00000105218
khk
ketohexokinase
chr5_-_69180227 4.47 ENSDART00000154816
zgc:171967
zgc:171967
chr13_-_31544365 4.43 ENSDART00000005670
dhrs7
dehydrogenase/reductase (SDR family) member 7
chr18_-_43866001 4.43 ENSDART00000150218
treh
trehalase (brush-border membrane glycoprotein)
chr12_-_850457 4.42 ENSDART00000022688
tob1b
transducer of ERBB2, 1b
chr21_-_30111134 4.42 ENSDART00000014223
slc23a1
solute carrier family 23 (ascorbic acid transporter), member 1
chr23_-_44903048 4.39 ENSDART00000149103
fhdc5
FH2 domain containing 5
chr11_+_14284866 4.36 ENSDART00000163729
si:ch211-262i1.3
si:ch211-262i1.3
chr14_+_28442963 4.35 ENSDART00000186495
acsl4a
acyl-CoA synthetase long chain family member 4a
chr7_-_24005268 4.34 ENSDART00000173608
si:dkey-183c6.9
si:dkey-183c6.9
chr25_-_24046870 4.32 ENSDART00000047569
igf2b
insulin-like growth factor 2b
chr22_+_38778649 4.31 ENSDART00000075873
alpi.2
alkaline phosphatase, intestinal, tandem duplicate 2
chr3_+_56876280 4.30 ENSDART00000154197
amn
amnion associated transmembrane protein
chr11_+_21910343 4.28 ENSDART00000161485
foxp4
forkhead box P4
chr6_-_2627488 4.24 ENSDART00000044089
ENSDART00000158333
ENSDART00000155109
hyi
hydroxypyruvate isomerase
chr15_+_32405959 4.23 ENSDART00000177269
si:ch211-162k9.6
si:ch211-162k9.6
chr10_+_9561066 4.22 ENSDART00000136281
si:ch211-243g18.2
si:ch211-243g18.2
chr22_+_38778854 4.22 ENSDART00000182926
ENSDART00000125466
alpi.2
alkaline phosphatase, intestinal, tandem duplicate 2
chr9_+_38420028 4.17 ENSDART00000135748
cyp27a1.2
cytochrome P450, family 27, subfamily A, polypeptide 1, gene 2

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2f1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
15.6 46.7 GO:0046415 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
9.7 48.7 GO:0006642 triglyceride mobilization(GO:0006642)
9.0 27.1 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
6.3 18.8 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
5.1 20.3 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
4.8 19.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
4.5 22.5 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
4.4 13.2 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
4.1 16.5 GO:0019626 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
4.0 15.8 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
3.7 11.0 GO:0009750 response to fructose(GO:0009750)
3.4 17.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
3.4 33.7 GO:0045444 fat cell differentiation(GO:0045444)
3.0 20.7 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
2.9 2.9 GO:0048338 axial mesoderm structural organization(GO:0048331) mesoderm structural organization(GO:0048338)
2.8 8.5 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
2.8 11.2 GO:0006867 asparagine transport(GO:0006867)
2.7 11.0 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
2.6 7.8 GO:0005991 trehalose metabolic process(GO:0005991)
2.6 12.9 GO:0035434 copper ion transmembrane transport(GO:0035434)
2.5 122.3 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
2.4 7.2 GO:2000193 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
2.1 17.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
2.1 20.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
1.9 13.0 GO:0045329 carnitine biosynthetic process(GO:0045329)
1.8 27.7 GO:0016486 peptide hormone processing(GO:0016486)
1.6 6.3 GO:0046144 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
1.5 4.4 GO:0015882 L-ascorbic acid transport(GO:0015882)
1.4 14.0 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
1.4 4.2 GO:0070640 calcitriol biosynthetic process from calciol(GO:0036378) vitamin D biosynthetic process(GO:0042368) cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108) vitamin D3 metabolic process(GO:0070640)
1.3 6.6 GO:0071422 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
1.2 21.2 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
1.2 5.0 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
1.2 3.7 GO:0006545 glycine biosynthetic process(GO:0006545)
1.2 9.8 GO:0042537 benzene-containing compound metabolic process(GO:0042537)
1.2 3.6 GO:0045724 positive regulation of cilium assembly(GO:0045724)
1.2 16.4 GO:0016556 mRNA modification(GO:0016556)
1.2 15.0 GO:0042572 retinol metabolic process(GO:0042572)
1.1 3.2 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
1.0 23.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
1.0 33.1 GO:0060030 dorsal convergence(GO:0060030)
1.0 5.9 GO:0071800 podosome assembly(GO:0071800)
1.0 3.9 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
1.0 2.9 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.9 7.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) pteridine-containing compound biosynthetic process(GO:0042559) tetrahydrobiopterin metabolic process(GO:0046146)
0.9 3.7 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.9 3.5 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.8 11.7 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.8 4.1 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.8 23.6 GO:0003323 type B pancreatic cell development(GO:0003323)
0.8 3.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.8 4.9 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.8 7.7 GO:1901571 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.8 6.0 GO:0009109 coenzyme catabolic process(GO:0009109)
0.7 2.2 GO:0051026 meiotic DNA repair synthesis(GO:0000711) chiasma assembly(GO:0051026)
0.7 3.6 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.7 4.3 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.7 8.6 GO:0018198 peptidyl-cysteine modification(GO:0018198)
0.7 4.2 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.7 2.0 GO:0060845 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
0.7 2.0 GO:0042823 water-soluble vitamin biosynthetic process(GO:0042364) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.6 3.9 GO:0006574 valine catabolic process(GO:0006574)
0.6 6.9 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.6 3.8 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.6 1.8 GO:0072020 proximal straight tubule development(GO:0072020)
0.6 28.5 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.6 1.7 GO:1903173 fatty alcohol metabolic process(GO:1903173)
0.6 2.2 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.5 1.6 GO:1901296 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.5 1.5 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.5 4.9 GO:0060612 adipose tissue development(GO:0060612)
0.5 2.4 GO:0010447 response to acidic pH(GO:0010447)
0.5 1.9 GO:0051660 establishment of centrosome localization(GO:0051660)
0.5 12.8 GO:0032355 response to estradiol(GO:0032355)
0.5 5.0 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.5 1.8 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.4 2.2 GO:0006833 water transport(GO:0006833)
0.4 12.3 GO:0043171 peptide catabolic process(GO:0043171)
0.4 1.7 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.4 2.2 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.4 17.8 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.4 0.8 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.4 6.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.4 4.7 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.4 2.1 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.4 2.1 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.4 1.4 GO:0008356 asymmetric cell division(GO:0008356)
0.4 1.4 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.3 4.7 GO:0050892 intestinal absorption(GO:0050892)
0.3 3.6 GO:0030719 P granule organization(GO:0030719)
0.3 1.3 GO:0042671 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.3 1.6 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.3 2.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.3 14.0 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.3 2.4 GO:0030104 water homeostasis(GO:0030104)
0.3 2.7 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3 1.8 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.3 2.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.3 9.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.3 2.8 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.3 1.9 GO:0006552 leucine catabolic process(GO:0006552)
0.3 1.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.3 2.2 GO:0034063 stress granule assembly(GO:0034063)
0.3 3.5 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.3 21.9 GO:0007596 blood coagulation(GO:0007596)
0.3 2.7 GO:0006108 malate metabolic process(GO:0006108)
0.3 23.4 GO:0007605 sensory perception of sound(GO:0007605)
0.3 6.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.3 4.3 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.2 1.0 GO:0045041 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.2 5.1 GO:0009409 response to cold(GO:0009409)
0.2 4.8 GO:0030497 fatty acid elongation(GO:0030497)
0.2 2.4 GO:0033151 V(D)J recombination(GO:0033151)
0.2 2.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 5.0 GO:0006491 N-glycan processing(GO:0006491)
0.2 0.9 GO:0070199 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.2 1.9 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.2 33.6 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.2 1.4 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.2 1.8 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.2 6.2 GO:0001878 response to yeast(GO:0001878)
0.2 12.4 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.2 6.5 GO:0048599 oocyte development(GO:0048599)
0.2 2.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.2 8.7 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.2 0.9 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 0.5 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.2 1.9 GO:0007197 regulation of smooth muscle contraction(GO:0006940) adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2 1.0 GO:0009268 response to pH(GO:0009268) cellular response to pH(GO:0071467)
0.2 1.0 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 5.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.2 3.7 GO:0051923 sulfation(GO:0051923)
0.2 1.2 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.2 0.7 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.2 2.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 0.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 2.7 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.1 4.1 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 0.4 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 0.3 GO:0006953 acute-phase response(GO:0006953)
0.1 1.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 5.2 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.1 11.1 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
0.1 3.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.4 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1 0.7 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 6.7 GO:0048545 response to steroid hormone(GO:0048545)
0.1 1.0 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.1 1.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.5 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.3 GO:0050817 coagulation(GO:0050817)
0.1 4.6 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.1 0.2 GO:0071569 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.3 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 3.8 GO:1901264 carbohydrate derivative transport(GO:1901264)
0.1 10.1 GO:0006979 response to oxidative stress(GO:0006979)
0.1 2.2 GO:0008643 carbohydrate transport(GO:0008643)
0.1 5.5 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 0.6 GO:0061511 centriole elongation(GO:0061511)
0.1 1.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 2.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 0.7 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 2.6 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 34.9 GO:0043066 negative regulation of apoptotic process(GO:0043066)
0.1 0.5 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 7.6 GO:0009615 response to virus(GO:0009615)
0.1 1.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 2.1 GO:0006828 manganese ion transport(GO:0006828)
0.1 0.3 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.3 GO:0010712 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.1 4.8 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.1 1.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 8.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 2.8 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 1.7 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 9.0 GO:0048793 pronephros development(GO:0048793)
0.1 1.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 1.0 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.2 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.0 1.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 2.5 GO:0007602 phototransduction(GO:0007602)
0.0 0.8 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 2.6 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 2.3 GO:0002218 activation of innate immune response(GO:0002218) pattern recognition receptor signaling pathway(GO:0002221) toll-like receptor signaling pathway(GO:0002224) innate immune response-activating signal transduction(GO:0002758)
0.0 0.4 GO:1901998 toxin transport(GO:1901998)
0.0 0.5 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 2.8 GO:0030203 glycosaminoglycan metabolic process(GO:0030203)
0.0 0.7 GO:0097324 melanocyte migration(GO:0097324)
0.0 3.5 GO:0007030 Golgi organization(GO:0007030)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.6 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 3.1 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.5 GO:0006986 response to unfolded protein(GO:0006986)
0.0 2.0 GO:0048884 neuromast development(GO:0048884)
0.0 0.2 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 4.9 GO:0009953 dorsal/ventral pattern formation(GO:0009953)
0.0 0.6 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 1.0 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 2.7 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.3 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.3 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.6 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 1.4 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.3 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.3 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 12.8 GO:0016567 protein ubiquitination(GO:0016567)
0.0 0.2 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 1.7 GO:0045333 cellular respiration(GO:0045333)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.3 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.4 GO:0006821 chloride transport(GO:0006821)
0.0 0.2 GO:0006991 ER-nucleus signaling pathway(GO:0006984) response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
9.7 48.7 GO:0034359 mature chylomicron(GO:0034359)
5.3 15.8 GO:0005948 acetolactate synthase complex(GO:0005948)
2.1 8.5 GO:0061689 tricellular tight junction(GO:0061689)
1.8 7.1 GO:0043073 germ cell nucleus(GO:0043073)
1.3 29.2 GO:0030667 secretory granule membrane(GO:0030667)
1.2 5.0 GO:0017177 glucosidase II complex(GO:0017177)
1.2 3.6 GO:0033391 chromatoid body(GO:0033391)
1.1 5.4 GO:0005581 collagen trimer(GO:0005581)
1.0 14.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.9 13.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.9 38.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.8 5.9 GO:0001891 phagocytic cup(GO:0001891)
0.7 75.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.7 2.0 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.6 2.4 GO:0097519 DNA recombinase complex(GO:0097519)
0.5 5.6 GO:0045095 keratin filament(GO:0045095)
0.5 24.9 GO:0005811 lipid particle(GO:0005811)
0.5 5.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.3 3.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 1.7 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.3 21.4 GO:0034707 chloride channel complex(GO:0034707)
0.3 2.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 23.0 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.3 2.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.3 5.2 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.3 0.8 GO:0070545 PeBoW complex(GO:0070545)
0.2 1.6 GO:0001650 fibrillar center(GO:0001650)
0.2 4.7 GO:0009925 basal plasma membrane(GO:0009925)
0.2 1.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 3.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2 1.8 GO:0042788 polysomal ribosome(GO:0042788)
0.2 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.2 6.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.2 9.4 GO:0016342 catenin complex(GO:0016342)
0.2 17.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 2.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 6.2 GO:0032587 ruffle membrane(GO:0032587)
0.1 15.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 1.5 GO:0048179 activin receptor complex(GO:0048179)
0.1 7.1 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 3.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 2.8 GO:0043186 P granule(GO:0043186)
0.1 1.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.5 GO:0045180 basal cortex(GO:0045180)
0.1 2.1 GO:0043195 terminal bouton(GO:0043195)
0.1 1.3 GO:0043296 apical junction complex(GO:0043296)
0.1 0.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 2.6 GO:0005902 microvillus(GO:0005902)
0.1 0.9 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 39.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 137.2 GO:0005576 extracellular region(GO:0005576)
0.1 2.1 GO:0000421 autophagosome membrane(GO:0000421)
0.1 70.7 GO:0005739 mitochondrion(GO:0005739)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 2.8 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 3.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0035101 FACT complex(GO:0035101)
0.0 0.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 9.1 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.5 GO:0005776 autophagosome(GO:0005776)
0.0 1.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.6 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 17.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
5.4 48.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
5.3 15.8 GO:0003984 acetolactate synthase activity(GO:0003984)
4.3 17.0 GO:0004657 proline dehydrogenase activity(GO:0004657)
4.0 15.9 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
3.5 10.5 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
3.4 27.2 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
3.0 12.0 GO:0004064 arylesterase activity(GO:0004064)
3.0 20.7 GO:0034632 retinol transporter activity(GO:0034632)
2.7 11.0 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
2.7 19.2 GO:0045735 nutrient reservoir activity(GO:0045735)
2.7 18.8 GO:0004126 cytidine deaminase activity(GO:0004126)
2.7 32.0 GO:0019238 cyclohydrolase activity(GO:0019238)
2.6 7.8 GO:0004555 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
2.6 13.0 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
2.6 12.9 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
2.4 157.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
2.1 2.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
2.1 6.2 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
1.9 21.2 GO:0035804 structural constituent of egg coat(GO:0035804)
1.9 19.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
1.9 15.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
1.9 11.2 GO:0015182 L-histidine transmembrane transporter activity(GO:0005290) L-asparagine transmembrane transporter activity(GO:0015182)
1.9 9.3 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
1.8 7.3 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
1.8 7.3 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.7 6.9 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
1.6 6.3 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
1.5 4.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
1.5 7.5 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
1.5 7.4 GO:2001070 starch binding(GO:2001070)
1.4 4.2 GO:0031073 vitamin D3 25-hydroxylase activity(GO:0030343) cholesterol 26-hydroxylase activity(GO:0031073)
1.3 6.6 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
1.2 5.0 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
1.2 4.8 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
1.2 3.6 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
1.2 15.4 GO:0016405 CoA-ligase activity(GO:0016405)
1.1 6.5 GO:0001784 phosphotyrosine binding(GO:0001784)
1.1 8.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
1.1 23.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
1.1 6.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
1.1 11.6 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
1.0 19.5 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
1.0 17.8 GO:0035497 cAMP response element binding(GO:0035497)
1.0 3.9 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.9 4.7 GO:0009374 biotin binding(GO:0009374)
0.9 6.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.9 2.6 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.8 12.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.8 46.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.8 5.6 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.7 6.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.6 1.9 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.6 2.4 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.5 13.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.5 2.7 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.5 3.7 GO:0070698 type I activin receptor binding(GO:0070698)
0.5 4.7 GO:0015250 water channel activity(GO:0015250)
0.5 6.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.5 3.4 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.5 1.9 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.5 10.3 GO:0010181 FMN binding(GO:0010181)
0.5 29.5 GO:0009055 electron carrier activity(GO:0009055)
0.5 1.4 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.4 13.7 GO:0030145 manganese ion binding(GO:0030145)
0.4 2.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.4 2.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.4 1.6 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.4 3.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.4 2.8 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.4 12.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.4 3.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.4 1.1 GO:0034618 arginine binding(GO:0034618)
0.4 7.6 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.4 31.0 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.4 5.7 GO:0015245 fatty acid transporter activity(GO:0015245)
0.3 1.7 GO:0008525 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine transporter activity(GO:0008525) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 4.1 GO:0043495 protein anchor(GO:0043495)
0.3 2.7 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.3 5.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.3 2.2 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.3 1.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.3 70.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 4.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3 9.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.3 1.5 GO:0046592 polyamine oxidase activity(GO:0046592)
0.3 2.0 GO:0004984 olfactory receptor activity(GO:0004984) odorant binding(GO:0005549)
0.3 7.4 GO:0016289 CoA hydrolase activity(GO:0016289)
0.3 3.5 GO:0051117 ATPase binding(GO:0051117)
0.2 24.6 GO:0005254 chloride channel activity(GO:0005254)
0.2 1.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 1.7 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.2 9.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 4.7 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.2 14.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.2 27.4 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.2 1.0 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.2 4.7 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.2 1.2 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.2 1.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 1.0 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.2 4.8 GO:0005112 Notch binding(GO:0005112)
0.2 4.9 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 1.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 2.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.2 1.9 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 1.0 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.2 1.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 5.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 2.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 0.5 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 25.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 4.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 2.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 3.7 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.2 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.1 1.0 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.5 GO:0004475 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.1 3.0 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 3.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 2.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.7 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 8.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 2.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 7.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 4.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.1 1.5 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 3.8 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
0.1 1.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.3 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 2.1 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 1.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 1.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 1.1 GO:1901677 phosphate transmembrane transporter activity(GO:1901677)
0.1 0.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 0.9 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.2 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 8.9 GO:0016853 isomerase activity(GO:0016853)
0.1 25.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 2.4 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 8.2 GO:0016798 hydrolase activity, acting on glycosyl bonds(GO:0016798)
0.1 2.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 2.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 2.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 6.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 8.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 3.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 1.8 GO:0051427 hormone receptor binding(GO:0051427)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 3.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.6 GO:0003823 antigen binding(GO:0003823)
0.0 0.5 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 15.2 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 1.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 1.5 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.8 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 40.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.5 18.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 3.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 6.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 8.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 8.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 3.4 PID ALK1 PATHWAY ALK1 signaling events
0.1 4.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
4.7 18.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
2.9 20.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
2.8 22.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
2.4 19.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.9 14.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
1.8 12.8 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
1.7 15.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
1.5 17.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
1.4 9.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.3 23.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
1.3 17.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
1.3 7.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.9 43.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.8 18.7 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.7 2.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.7 5.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.6 3.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.6 13.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.6 5.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.6 12.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.5 3.0 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.4 6.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.4 3.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.3 6.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 2.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.2 17.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.2 2.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 3.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 1.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.2 3.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 2.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.8 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 2.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.7 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.1 1.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 3.8 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 3.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 3.5 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 10.6 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.1 1.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 11.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 4.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 10.5 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.1 1.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 0.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 3.1 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 1.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.2 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks