ISMARA results: nr2f2

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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for nr2f2

Z-value: 1.98

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Transcription factors associated with nr2f2

Gene Symbol	Gene ID	Gene Info
nr2f2 NCBI UniProt	ENSDARG00000040926	nuclear receptor subfamily 2, group F, member 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
nr2f2	dr11_v1_chr18_-_23875370_23875370	-0.38	1.6e-04	Click!

Activity profile of nr2f2 motif

Sorted Z-values of nr2f2 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr15_-_108414 Show fit	46.04	ENSDART00000170044	apoa1b NCBI UniProt Show fit	apolipoprotein A-Ib
chr19_+_9277327 Show fit	37.77	ENSDART00000104623 ENSDART00000151164	si:rp71-15k1.1 NCBI UniProt Show fit	si:rp71-15k1.1
chr17_-_30702411 Show fit	36.59	ENSDART00000114358	zgc:194392 NCBI UniProt Show fit	zgc:194392
chr9_-_9982696 Show fit	35.84	ENSDART00000192548 ENSDART00000125852	ugt1ab NCBI UniProt Show fit	UDP glucuronosyltransferase 1 family a, b
chr7_+_25036188 Show fit	35.51	ENSDART00000163957 ENSDART00000169749	sb:cb1058 NCBI UniProt Show fit	sb:cb1058
chr18_+_13162728 Show fit	35.23	ENSDART00000101472	tat NCBI UniProt Show fit	tyrosine aminotransferase
chr10_-_322769 Show fit	35.19	ENSDART00000165244	akt2l NCBI UniProt Show fit	v-akt murine thymoma viral oncogene homolog 2, like
chr13_+_37022601 Show fit	33.28	ENSDART00000131800 ENSDART00000041300	esr2b NCBI UniProt Show fit	estrogen receptor 2b
chr6_+_60055168 Show fit	30.24	ENSDART00000008752	pck1 NCBI UniProt Show fit	phosphoenolpyruvate carboxykinase 1 (soluble)
chr19_-_27564458 Show fit	25.13	ENSDART00000123155	si:dkeyp-46h3.6 NCBI UniProt Show fit	si:dkeyp-46h3.6

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2f2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.7	87.8	GO:0017144	drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
10.1	60.8	GO:0034372	triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372) reverse cholesterol transport(GO:0043691)
3.2	54.2	GO:0060046	binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
8.2	40.9	GO:0019482	beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
12.7	38.2	GO:0005991	trehalose metabolic process(GO:0005991)
5.9	35.2	GO:0006572	tyrosine catabolic process(GO:0006572)
3.3	33.3	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
7.6	30.2	GO:0006114	glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.1	28.0	GO:0006869	lipid transport(GO:0006869)
0.3	22.7	GO:0006956	complement activation(GO:0006956)

Showing 1 to 10 of 144 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	133.6	GO:0005576	extracellular region(GO:0005576)
0.0	72.3	GO:0016021	integral component of membrane(GO:0016021)
5.1	66.4	GO:0042627	chylomicron(GO:0042627)
0.1	51.5	GO:0031012	extracellular matrix(GO:0031012)
0.1	46.1	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	43.2	GO:0005739	mitochondrion(GO:0005739)
3.0	14.8	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.1	14.3	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
3.1	12.5	GO:0061689	tricellular tight junction(GO:0061689)
3.9	11.8	GO:0034362	low-density lipoprotein particle(GO:0034362)

Showing 1 to 10 of 49 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.6	101.5	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
4.9	54.2	GO:0035804	structural constituent of egg coat(GO:0035804)
0.8	48.2	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.1	47.1	GO:0008270	zinc ion binding(GO:0008270)
9.2	46.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.5	38.6	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
12.7	38.2	GO:0015927	alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.2	35.7	GO:0004252	serine-type endopeptidase activity(GO:0004252)
1.2	35.2	GO:0008483	transaminase activity(GO:0008483)
4.8	33.3	GO:1903924	estradiol binding(GO:1903924)

Showing 1 to 10 of 131 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.8	78.2	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.4	9.7	PID ARF6 PATHWAY	Arf6 signaling events
0.1	7.1	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	6.7	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	5.3	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.3	5.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2	5.0	PID ALK1 PATHWAY	ALK1 signaling events
0.1	4.3	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	3.8	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.1	1.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway

Showing 1 to 10 of 15 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
7.1	42.8	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.2	38.1	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
10.1	30.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.2	26.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
6.2	24.8	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
2.9	23.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
2.0	20.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.3	15.1	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
1.5	14.8	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.7	12.7	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells

Showing 1 to 10 of 32 entries

Results for nr2f2

Z-value: 1.98

Motif logo

Transcription factors associated with nr2f2

Activity-expression correlation:

Activity profile of nr2f2 motif

Sorted Z-values of nr2f2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2f2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: