Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for nr3c2

Z-value: 0.57

Motif logo

logo of

Transcription factors associated with nr3c2

Gene Symbol Gene ID Gene Info
nr3c2
ENSDARG00000102082 nuclear receptor subfamily 3, group C, member 2
nr3c2
ENSDARG00000115513 nuclear receptor subfamily 3, group C, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr3c2dr11_v1_chr1_-_37087966_370879660.066.0e-01Click!

Activity profile of nr3c2 motif

Sorted Z-values of nr3c2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_41096058 13.27 ENSDART00000028373
fkbp5
FK506 binding protein 5
chr6_+_41099787 8.75 ENSDART00000186884
fkbp5
FK506 binding protein 5
chr24_-_38097305 6.03 ENSDART00000124321
crp2
C-reactive protein 2
chr16_+_50089417 5.71 ENSDART00000153675
nr1d2a
nuclear receptor subfamily 1, group D, member 2a
chr14_-_46113321 5.53 ENSDART00000169040
ENSDART00000161475
ENSDART00000124925
si:ch211-235e9.8
si:ch211-235e9.8
chr7_+_48288762 3.72 ENSDART00000083569
oaz2b
ornithine decarboxylase antizyme 2b
chr4_-_15420452 3.47 ENSDART00000016230
plxna4
plexin A4
chr14_-_28001986 3.07 ENSDART00000054115
tsc22d3
TSC22 domain family, member 3
chr7_+_58699718 2.93 ENSDART00000049264
sdr16c5b
short chain dehydrogenase/reductase family 16C, member 5b
chr23_+_44732863 2.83 ENSDART00000160044
ENSDART00000172268
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr2_-_32512648 2.27 ENSDART00000170674
abcf2a
ATP-binding cassette, sub-family F (GCN20), member 2a
chr8_+_7359294 1.89 ENSDART00000121708
pcsk1nl
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr16_+_46430627 1.76 ENSDART00000127681
rpz6
rapunzel 6
chr5_-_43935460 1.75 ENSDART00000166152
ENSDART00000188969
si:ch211-204c21.1
si:ch211-204c21.1
chr5_+_9417409 1.72 ENSDART00000125421
ENSDART00000130265
ugt2b5
UDP glucuronosyltransferase 2 family, polypeptide B5
chr5_-_54792239 1.48 ENSDART00000056213
pik3r1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr3_-_25275364 1.35 ENSDART00000163782
ENSDART00000145420
ENSDART00000133718
ENSDART00000055492
ddx5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr18_-_19491162 1.35 ENSDART00000090413
snapc5
small nuclear RNA activating complex, polypeptide 5
chr1_-_28473350 1.33 ENSDART00000190608
ENSDART00000148175
si:ch1073-440b2.1
si:ch1073-440b2.1
chr3_-_40051425 1.24 ENSDART00000146700
llgl1
lethal giant larvae homolog 1 (Drosophila)
chr5_+_9382301 1.20 ENSDART00000124017
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr25_+_28772632 1.05 ENSDART00000160619
slc41a2a
solute carrier family 41 (magnesium transporter), member 2a
chr11_-_34147205 0.98 ENSDART00000173216
atp13a3
ATPase 13A3
chr10_+_20364009 0.94 ENSDART00000186139
ENSDART00000080395
golga7
golgin A7
chr5_-_43935119 0.88 ENSDART00000142271
si:ch211-204c21.1
si:ch211-204c21.1
chr24_-_23784701 0.86 ENSDART00000090368
sgk3
serum/glucocorticoid regulated kinase family, member 3
chr11_+_5880562 0.74 ENSDART00000129663
ENSDART00000130768
ENSDART00000160909
dazap1
DAZ associated protein 1
chr11_-_43473824 0.71 ENSDART00000179561
tmem63bb
transmembrane protein 63Bb
chr3_-_37476475 0.70 ENSDART00000148107
si:ch211-278a6.1
si:ch211-278a6.1
chr5_-_9540641 0.57 ENSDART00000124384
ENSDART00000160079
gak
cyclin G associated kinase
chr20_+_54336137 0.57 ENSDART00000113792
cipcb
CLOCK-interacting pacemaker b
chr4_+_11723852 0.52 ENSDART00000028820
mkln1
muskelin 1, intracellular mediator containing kelch motifs
chr17_+_29345606 0.46 ENSDART00000086164
kctd3
potassium channel tetramerization domain containing 3
chr11_+_34522554 0.46 ENSDART00000109833
zmat3
zinc finger, matrin-type 3
chr18_-_44611252 0.42 ENSDART00000173095
spred3
sprouty-related, EVH1 domain containing 3
chr6_-_27057702 0.42 ENSDART00000149363
stk25a
serine/threonine kinase 25a
chr15_-_24883956 0.40 ENSDART00000113199
aipl1
aryl hydrocarbon receptor interacting protein-like 1
chr10_+_8554929 0.35 ENSDART00000190849
tbc1d10ab
TBC1 domain family, member 10Ab
chr15_-_18429550 0.32 ENSDART00000136208
ncam1b
neural cell adhesion molecule 1b
chr8_-_45835056 0.29 ENSDART00000022242
ogdha
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr6_+_50451337 0.27 ENSDART00000155051
mych
myelocytomatosis oncogene homolog
chr5_+_9360394 0.25 ENSDART00000124642
FP236810.2

chr22_+_24770744 0.24 ENSDART00000142882
si:rp71-23d18.4
si:rp71-23d18.4
chr1_-_39909985 0.19 ENSDART00000181673
stox2a
storkhead box 2a
chr24_-_20641000 0.16 ENSDART00000166135
zbtb47b
zinc finger and BTB domain containing 47b
chr8_-_45834825 0.10 ENSDART00000132965
ogdha
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr10_+_29849497 0.06 ENSDART00000099994
ENSDART00000132212
hspa8
heat shock protein 8
chr22_-_36519590 0.06 ENSDART00000129318
CABZ01045212.1

chr8_-_50525360 0.05 ENSDART00000175648
CABZ01060030.1

chr4_+_53976731 0.03 ENSDART00000165813
si:ch211-249c2.1
si:ch211-249c2.1
chr16_+_11188810 0.01 ENSDART00000186011
cicb
capicua transcriptional repressor b

Network of associatons between targets according to the STRING database.

First level regulatory network of nr3c2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0007414 axonal defasciculation(GO:0007414)
0.7 22.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.3 5.5 GO:0008089 anterograde axonal transport(GO:0008089)
0.3 1.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 3.7 GO:0006595 polyamine metabolic process(GO:0006595)
0.1 2.7 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.1 2.8 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.6 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 5.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 1.5 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 3.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 1.2 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 0.6 GO:0072318 clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
0.1 0.4 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.9 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.7 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 5.2 GO:0009617 response to bacterium(GO:0009617)
0.0 0.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 3.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.9 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 2.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 1.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 22.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.9 3.7 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.7 GO:0034046 poly(G) binding(GO:0034046)
0.1 2.8 GO:0001671 ATPase activator activity(GO:0001671)
0.1 3.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 6.0 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.2 GO:0045159 myosin II binding(GO:0045159)
0.1 2.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 1.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 5.7 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.7 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.4 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.0 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 22.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 3.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis