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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for nr4a1

Z-value: 1.26

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Transcription factors associated with nr4a1

Gene Symbol Gene ID Gene Info
nr4a1
ENSDARG00000000796 nuclear receptor subfamily 4, group A, member 1
nr4a1
ENSDARG00000109473 nuclear receptor subfamily 4, group A, member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr4a1dr11_v1_chr23_-_32162810_32162810-0.223.0e-02Click!

Activity profile of nr4a1 motif

Sorted Z-values of nr4a1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_17745345 21.52 ENSDART00000132690
ENSDART00000135376
si:dkey-200l5.4
si:dkey-200l5.4
chr6_-_31348999 21.36 ENSDART00000153734
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr5_+_1278092 16.37 ENSDART00000147972
ENSDART00000159783
dnm1a
dynamin 1a
chr8_-_14052349 12.11 ENSDART00000135811
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr14_+_14225048 11.04 ENSDART00000168749
nlgn3a
neuroligin 3a
chr20_-_10120442 10.55 ENSDART00000144970
meis2b
Meis homeobox 2b
chr4_+_12615836 9.56 ENSDART00000003583
lmo3
LIM domain only 3
chr3_-_22212764 8.85 ENSDART00000155490
maptb
microtubule-associated protein tau b
chr2_-_11912347 8.57 ENSDART00000023851
abhd3
abhydrolase domain containing 3
chr12_+_9817440 8.36 ENSDART00000137081
ENSDART00000123712
rundc3ab
RUN domain containing 3Ab
chr14_+_36246726 8.07 ENSDART00000105602
elovl6
ELOVL fatty acid elongase 6
chr17_-_7371564 8.05 ENSDART00000060336
rab32b
RAB32b, member RAS oncogene family
chr2_+_34767171 7.95 ENSDART00000145451
astn1
astrotactin 1
chr4_-_7212875 7.86 ENSDART00000161297
lrrn3b
leucine rich repeat neuronal 3b
chr11_-_17713987 7.76 ENSDART00000090401
fam19a4b
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4b
chr14_-_32258759 7.49 ENSDART00000052949
fgf13a
fibroblast growth factor 13a
chr9_-_43142636 7.24 ENSDART00000134349
ENSDART00000181835
ccdc141
coiled-coil domain containing 141
chr13_-_21739142 7.12 ENSDART00000078460
si:dkey-191g9.5
si:dkey-191g9.5
chr24_+_4977862 7.07 ENSDART00000114537
zic4
zic family member 4
chr14_+_14224730 6.89 ENSDART00000180112
ENSDART00000184891
ENSDART00000174760
nlgn3a
neuroligin 3a
chr6_-_10320676 6.85 ENSDART00000151247
scn1lab
sodium channel, voltage-gated, type I like, alpha b
chr20_-_36917670 6.66 ENSDART00000046716
cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr12_-_33568174 6.43 ENSDART00000142329
tdrkh
tudor and KH domain containing
chr24_+_4978055 6.37 ENSDART00000045813
zic4
zic family member 4
chr13_-_41155472 6.31 ENSDART00000160588
si:dkeyp-86d6.2
si:dkeyp-86d6.2
chr1_-_50838160 6.24 ENSDART00000163939
ENSDART00000165111
zgc:154142
zgc:154142
chr5_+_24282570 6.10 ENSDART00000041905
zdhhc23a
zinc finger, DHHC-type containing 23a
chr12_+_21525496 5.87 ENSDART00000152974
ca10a
carbonic anhydrase Xa
chr14_+_36628131 5.75 ENSDART00000188625
ENSDART00000125345
TENM3
si:dkey-237h12.3
chr22_+_30184039 5.66 ENSDART00000049075
add3a
adducin 3 (gamma) a
chr11_+_1409622 5.57 ENSDART00000157042
ppp1r3db
protein phosphatase 1, regulatory subunit 3Db
chr6_-_35738836 5.53 ENSDART00000111642
brinp3a.1
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr9_-_30346279 5.36 ENSDART00000089488
sytl5
synaptotagmin-like 5
chr20_-_14206698 5.32 ENSDART00000082441
dlgap2b
discs, large (Drosophila) homolog-associated protein 2b
chr5_-_50600512 5.17 ENSDART00000190318
mctp1a
multiple C2 domains, transmembrane 1a
chr8_+_39634114 5.15 ENSDART00000144293
msi1
musashi RNA-binding protein 1
chr12_+_24562667 5.09 ENSDART00000056256
nrxn1a
neurexin 1a
chr21_+_10076203 5.09 ENSDART00000190383
CABZ01043506.1

chr22_-_16997475 5.07 ENSDART00000090237
nfia
nuclear factor I/A
chr21_-_30648106 4.89 ENSDART00000160800
ENSDART00000177022
phka1b
phosphorylase kinase, alpha 1b (muscle)
chr19_+_2275019 4.75 ENSDART00000136138
itgb8
integrin, beta 8
chr5_+_65493699 4.75 ENSDART00000161567
si:dkey-21e5.1
si:dkey-21e5.1
chr1_+_54115839 4.73 ENSDART00000180214
LO017722.2

chr21_+_7900107 4.65 ENSDART00000056560
ch25hl2
cholesterol 25-hydroxylase like 2
chr2_-_42827336 4.51 ENSDART00000140913
adcy8
adenylate cyclase 8 (brain)
chr18_+_27926839 4.33 ENSDART00000191835
hipk3b
homeodomain interacting protein kinase 3b
chr11_-_6974022 4.31 ENSDART00000172851
COMP
si:ch211-43f4.1
chr7_+_44484853 4.28 ENSDART00000189079
ENSDART00000121826
bean1
brain expressed, associated with NEDD4, 1
chr6_-_53204808 3.85 ENSDART00000160955
slc38a3b
solute carrier family 38, member 3b
chr9_-_43082945 3.72 ENSDART00000142257
ccdc141
coiled-coil domain containing 141
chr18_-_42333428 3.66 ENSDART00000034225
cntn5
contactin 5
chr19_+_19652439 3.63 ENSDART00000165934
hibadha
3-hydroxyisobutyrate dehydrogenase a
chr24_-_24848612 3.55 ENSDART00000190941
crhb
corticotropin releasing hormone b
chr3_-_37351225 3.51 ENSDART00000174685
si:ch211-278a6.1
si:ch211-278a6.1
chr1_+_44826367 3.35 ENSDART00000146962
STX3
zgc:165520
chr1_+_31638274 3.31 ENSDART00000057885
fgf8b
fibroblast growth factor 8 b
chr24_+_22022109 3.25 ENSDART00000133686
ropn1l
rhophilin associated tail protein 1-like
chr5_+_24156170 3.25 ENSDART00000136570
slc25a15b
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15b
chr8_-_45834825 3.05 ENSDART00000132965
ogdha
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr24_-_8214253 3.04 ENSDART00000160432
CABZ01077956.1

chr8_+_10404310 3.01 ENSDART00000185573
tbc1d22b
TBC1 domain family, member 22B
chr17_+_450956 2.99 ENSDART00000183022
ENSDART00000171386
zgc:194887
zgc:194887
chr22_-_17595310 2.98 ENSDART00000099056
gpx4a
glutathione peroxidase 4a
chr7_+_15871408 2.96 ENSDART00000014572
pax6b
paired box 6b
chr6_-_40044111 2.93 ENSDART00000154347
si:dkey-197j19.5
si:dkey-197j19.5
chr7_+_20524064 2.88 ENSDART00000052917
slc3a2a
solute carrier family 3 (amino acid transporter heavy chain), member 2a
chr24_+_2961098 2.87 ENSDART00000163760
ENSDART00000170835
eci2
enoyl-CoA delta isomerase 2
chr12_-_48127985 2.87 ENSDART00000193805
npffr1
neuropeptide FF receptor 1
chr15_-_11341635 2.84 ENSDART00000055220
rab30
RAB30, member RAS oncogene family
chr15_+_1705167 2.78 ENSDART00000081940
otol1b
otolin 1b
chr8_-_45835056 2.74 ENSDART00000022242
ogdha
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr8_-_15991473 2.70 ENSDART00000151746
agbl4
ATP/GTP binding protein-like 4
chr8_-_15991801 2.69 ENSDART00000132005
agbl4
ATP/GTP binding protein-like 4
chr19_+_32158010 2.68 ENSDART00000005255
mrpl53
mitochondrial ribosomal protein L53
chr4_-_17391091 2.68 ENSDART00000056002
th2
tyrosine hydroxylase 2
chr8_+_21406769 2.64 ENSDART00000135766
si:dkey-163f12.6
si:dkey-163f12.6
chr2_-_41562868 2.63 ENSDART00000084597
d2hgdh
D-2-hydroxyglutarate dehydrogenase
chr20_+_40150612 2.59 ENSDART00000143680
ENSDART00000109681
ENSDART00000101041
ENSDART00000121818
trdn
triadin
chr8_+_51084993 2.55 ENSDART00000127709
ENSDART00000053768
DISP3
si:dkey-32e23.6
chr22_+_24673168 2.51 ENSDART00000135257
si:rp71-23d18.8
si:rp71-23d18.8
chr7_-_42206720 2.50 ENSDART00000110907
itfg1
integrin alpha FG-GAP repeat containing 1
chr18_+_31410652 2.49 ENSDART00000098504
def8
differentially expressed in FDCP 8 homolog (mouse)
chr16_-_50203058 2.47 ENSDART00000154570
vsig10l
V-set and immunoglobulin domain containing 10 like
chr6_+_41957280 2.44 ENSDART00000050114
oxtr
oxytocin receptor
chr10_+_41668483 2.38 ENSDART00000127073
lrrc75bb
leucine rich repeat containing 75Bb
chr20_-_27711970 2.37 ENSDART00000139637
zbtb25
zinc finger and BTB domain containing 25
chr22_-_16997246 2.36 ENSDART00000090242
nfia
nuclear factor I/A
chr12_+_46708920 2.35 ENSDART00000153089
exoc7
exocyst complex component 7
chr4_-_77377596 2.34 ENSDART00000186068
slco1e1
solute carrier organic anion transporter family, member 1E1
chr5_-_26330313 2.33 ENSDART00000148656
arvcfb
ARVCF, delta catenin family member b
chr5_+_59449762 2.31 ENSDART00000150230
clip2
CAP-GLY domain containing linker protein 2
chr18_-_4957022 2.27 ENSDART00000101686
zbbx
zinc finger, B-box domain containing
chr18_+_27515640 2.26 ENSDART00000181593
tp53i11b
tumor protein p53 inducible protein 11b
chr11_+_12175162 2.24 ENSDART00000125446
si:ch211-156l18.7
si:ch211-156l18.7
chr22_-_20126230 2.22 ENSDART00000138688
creb3l3a
cAMP responsive element binding protein 3-like 3a
chr10_+_11265387 2.22 ENSDART00000038888
hsdl2
hydroxysteroid dehydrogenase like 2
chr20_+_46897504 2.21 ENSDART00000158124
si:ch73-21k16.1
si:ch73-21k16.1
chr7_+_42206847 2.20 ENSDART00000149250
phkb
phosphorylase kinase, beta
chr10_-_29892486 2.20 ENSDART00000099983
bsx
brain-specific homeobox
chr13_+_22479988 2.18 ENSDART00000188182
ENSDART00000192972
ENSDART00000178372
ldb3a
LIM domain binding 3a
chr12_-_29305220 2.17 ENSDART00000153458
sh2d4bb
SH2 domain containing 4Bb
chr18_+_9382847 2.13 ENSDART00000061886
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr6_+_29288223 2.12 ENSDART00000112099
zgc:172121
zgc:172121
chr8_+_26083808 2.08 ENSDART00000099283
dalrd3
DALR anticodon binding domain containing 3
chr15_-_16884912 2.05 ENSDART00000062135
zgc:103681
zgc:103681
chr22_-_11833317 2.05 ENSDART00000125423
ENSDART00000000192
ptpn4b
protein tyrosine phosphatase, non-receptor type 4b
chr23_-_9859989 2.03 ENSDART00000005015
prkcbp1l
protein kinase C binding protein 1, like
chr5_-_36549024 2.00 ENSDART00000097671
zgc:158432
zgc:158432
chr5_+_19448078 1.95 ENSDART00000088968
ube3b
ubiquitin protein ligase E3B
chr19_+_3056450 1.94 ENSDART00000141324
ENSDART00000082353
hsf1
heat shock transcription factor 1
chr6_-_39765546 1.93 ENSDART00000185767
pfkmb
phosphofructokinase, muscle b
chr17_+_30545895 1.92 ENSDART00000076739
nhsl1a
NHS-like 1a
chr12_-_31457301 1.90 ENSDART00000043887
ENSDART00000148603
acsl5
acyl-CoA synthetase long chain family member 5
chr4_-_2975461 1.87 ENSDART00000150794
plekha5
pleckstrin homology domain containing, family A member 5
chr1_-_23110740 1.79 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr6_-_10912424 1.78 ENSDART00000036456
cycsb
cytochrome c, somatic b
chr14_+_48045193 1.74 ENSDART00000124773
ppid
peptidylprolyl isomerase D
chr5_+_10046643 1.74 ENSDART00000137543
ENSDART00000186917
gstt2
glutathione S-transferase theta 2
chr17_+_41463942 1.72 ENSDART00000075331
insm1b
insulinoma-associated 1b
chr6_+_515181 1.71 ENSDART00000171374
CACNA1I (1 of many)
si:ch73-379f7.5
chr24_-_6628359 1.71 ENSDART00000169731
arhgap21a
Rho GTPase activating protein 21a
chr12_+_21697540 1.66 ENSDART00000153412
pkd1b
polycystic kidney disease 1b
chr18_-_2433011 1.63 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr7_-_51775688 1.61 ENSDART00000149793
bmp15
bone morphogenetic protein 15
chr18_-_15771551 1.56 ENSDART00000130931
ENSDART00000154079
si:ch211-219a15.3
si:ch211-219a15.3
chr23_+_30730121 1.51 ENSDART00000134141
asxl1
additional sex combs like transcriptional regulator 1
chr7_-_44909540 1.47 ENSDART00000193378
ENSDART00000109534
cdh16
cadherin 16, KSP-cadherin
chr23_+_9206350 1.45 ENSDART00000136236
si:dkey-66g10.2
si:dkey-66g10.2
chr10_+_7563755 1.45 ENSDART00000165877
purg
purine-rich element binding protein G
chr20_+_13883131 1.43 ENSDART00000003248
ENSDART00000152611
nek2
NIMA-related kinase 2
chr23_-_24488696 1.41 ENSDART00000155593
tmem82
transmembrane protein 82
chr7_+_17229282 1.40 ENSDART00000097982
slc6a5
solute carrier family 6 (neurotransmitter transporter), member 5
chr1_-_53988017 1.39 ENSDART00000003097
RHOU (1 of many)
si:ch211-133l11.10
chr15_-_6946286 1.34 ENSDART00000019330
ech1
enoyl CoA hydratase 1, peroxisomal
chr6_-_41135215 1.32 ENSDART00000001861
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr5_+_19413838 1.32 ENSDART00000089014
ENSDART00000146215
myo1ha
myosin IHa
chr5_-_3839285 1.32 ENSDART00000122292
mlxipl
MLX interacting protein like
chr20_+_37825804 1.29 ENSDART00000152865
tatdn3
TatD DNase domain containing 3
chr7_-_31794878 1.29 ENSDART00000099748
nap1l4b
nucleosome assembly protein 1-like 4b
chr17_-_17764801 1.25 ENSDART00000155261
slirp
SRA stem-loop interacting RNA binding protein
chr11_+_11201096 1.23 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myom2a
myomesin 2a
chr4_-_19921410 1.22 ENSDART00000184359
ENSDART00000179965
BX323820.1

chr8_+_26125218 1.21 ENSDART00000145095
celsr3
cadherin, EGF LAG seven-pass G-type receptor 3
chr3_-_30388525 1.20 ENSDART00000183790
lrrc4ba
leucine rich repeat containing 4Ba
chr2_-_8688759 1.19 ENSDART00000010257
miga1
mitoguardin 1
chr9_-_38036984 1.17 ENSDART00000134574
hacd2
3-hydroxyacyl-CoA dehydratase 2
chr4_-_16451375 1.16 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
wu:fc23c09
chr1_-_58868306 1.14 ENSDART00000166615
dnm2b
dynamin 2b
chr5_-_23200880 1.10 ENSDART00000051531
iqcd
IQ motif containing D
chr23_+_24272421 1.08 ENSDART00000029974
clcnk
chloride channel K
chr3_-_27915270 1.08 ENSDART00000115370
mettl22
methyltransferase like 22
chr6_+_13206516 1.06 ENSDART00000036927
ndufs1
NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr14_-_7409364 1.03 ENSDART00000036463
dnd1
DND microRNA-mediated repression inhibitor 1
chr19_-_40985308 1.02 ENSDART00000132986
ENSDART00000142360
si:ch211-120e1.7
si:ch211-120e1.7
chr6_+_40952031 0.96 ENSDART00000189219
patz1
POZ (BTB) and AT hook containing zinc finger 1
chr17_+_32374876 0.96 ENSDART00000183851
ywhaqb
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
chr7_-_24005268 0.95 ENSDART00000173608
si:dkey-183c6.9
si:dkey-183c6.9
chr5_+_45677781 0.94 ENSDART00000163120
ENSDART00000126537
gc
group-specific component (vitamin D binding protein)
chr21_+_23953181 0.92 ENSDART00000145541
ENSDART00000065599
ENSDART00000112869
cadm1a
cell adhesion molecule 1a
chr7_+_32021669 0.90 ENSDART00000173976
mettl15
methyltransferase like 15
chr13_+_22480496 0.89 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
ldb3a
LIM domain binding 3a
chr3_+_39566999 0.89 ENSDART00000146867
aldoaa
aldolase a, fructose-bisphosphate, a
chr21_+_4320769 0.89 ENSDART00000168553
HTRA2 (1 of many)
si:dkey-84o3.4
chr20_-_26060154 0.89 ENSDART00000151950
serac1
serine active site containing 1
chr6_-_8498676 0.85 ENSDART00000148627
pglyrp2
peptidoglycan recognition protein 2
chr21_-_43527198 0.84 ENSDART00000126092
irs4a
insulin receptor substrate 4a
chr5_+_38462121 0.84 ENSDART00000144425
gltpd2
glycolipid transfer protein domain containing 2
chr7_+_30202104 0.83 ENSDART00000173525
wdr76
WD repeat domain 76
chr7_+_31132588 0.81 ENSDART00000173702
tjp1a
tight junction protein 1a
chr7_+_56253914 0.79 ENSDART00000073594
ankrd11
ankyrin repeat domain 11
chr23_+_3538463 0.77 ENSDART00000172758
si:dkey-9l20.3
si:dkey-9l20.3
chr3_+_24050043 0.76 ENSDART00000151788
cbx1a
chromobox homolog 1a (HP1 beta homolog Drosophila)
chr7_+_38667066 0.76 ENSDART00000013394
mtch2
mitochondrial carrier homolog 2
chr3_+_23677351 0.75 ENSDART00000023674
hoxb9a
homeobox B9a
chr8_-_8698607 0.73 ENSDART00000046712
zgc:86609
zgc:86609
chr3_-_41292275 0.71 ENSDART00000144088
sdk1a
sidekick cell adhesion molecule 1a
chr12_-_29305533 0.71 ENSDART00000189410
sh2d4bb
SH2 domain containing 4Bb
chr20_+_13883353 0.67 ENSDART00000188006
nek2
NIMA-related kinase 2
chr7_-_19146925 0.65 ENSDART00000142924
ENSDART00000009695
kirrel1a
kirre like nephrin family adhesion molecule 1a
chr5_-_26323137 0.64 ENSDART00000133823
arvcfb
ARVCF, delta catenin family member b
chr17_-_47305034 0.62 ENSDART00000150116
alk
ALK receptor tyrosine kinase
chr13_+_24853578 0.62 ENSDART00000145865
si:dkey-24f15.2
si:dkey-24f15.2
chr2_-_44971551 0.61 ENSDART00000018818
mul1a
mitochondrial E3 ubiquitin protein ligase 1a
chr16_-_16619854 0.61 ENSDART00000150512
ENSDART00000191306
ENSDART00000181773
ENSDART00000183231
cyp21a2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr13_+_31603988 0.59 ENSDART00000030646
six6a
SIX homeobox 6a
chr10_+_7564106 0.57 ENSDART00000159042
purg
purine-rich element binding protein G
chr7_+_38588866 0.57 ENSDART00000015682
ndufs3
NADH dehydrogenase (ubiquinone) Fe-S protein 3, (NADH-coenzyme Q reductase)
chr7_+_38267136 0.56 ENSDART00000173613
gpatch1
G patch domain containing 1
chr6_+_29288006 0.52 ENSDART00000043496
zgc:172121
zgc:172121
chr11_+_33312601 0.49 ENSDART00000188024
cntnap5l
contactin associated protein-like 5 like
chr7_-_31794476 0.49 ENSDART00000142385
nap1l4b
nucleosome assembly protein 1-like 4b
chr15_+_40281693 0.46 ENSDART00000186565
gal3st2
galactose-3-O-sulfotransferase 2
chr6_-_8498908 0.41 ENSDART00000149222
pglyrp2
peptidoglycan recognition protein 2
chr2_+_10127762 0.40 ENSDART00000100726
insl5b
insulin-like 5b
chr2_+_13710439 0.39 ENSDART00000155712
ebna1bp2
EBNA1 binding protein 2
chr12_-_6880694 0.36 ENSDART00000171846
pcdh15b
protocadherin-related 15b
chr15_+_24676905 0.34 ENSDART00000078014
ENSDART00000143137
poldip2
polymerase (DNA-directed), delta interacting protein 2
chr15_-_12270857 0.34 ENSDART00000170093
si:dkey-36i7.3
si:dkey-36i7.3
chr3_-_51109286 0.34 ENSDART00000172010
si:ch211-148f13.1
si:ch211-148f13.1
chr19_+_5146460 0.30 ENSDART00000150740
si:dkey-89b17.4
si:dkey-89b17.4

Network of associatons between targets according to the STRING database.

First level regulatory network of nr4a1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 21.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
2.3 6.8 GO:1904059 regulation of locomotor rhythm(GO:1904059)
1.9 13.4 GO:0021534 cell proliferation in hindbrain(GO:0021534)
1.7 8.6 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
1.6 17.9 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
1.2 3.5 GO:0035902 response to immobilization stress(GO:0035902)
1.1 8.0 GO:0007158 neuron cell-cell adhesion(GO:0007158)
1.1 3.2 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
1.0 3.9 GO:0006867 asparagine transport(GO:0006867)
0.9 17.5 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.9 2.7 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.8 3.3 GO:0048240 sperm capacitation(GO:0048240)
0.8 2.4 GO:0021985 parturition(GO:0007567) neurohypophysis development(GO:0021985) maternal process involved in parturition(GO:0060137)
0.8 10.6 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.6 1.9 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.6 3.6 GO:0006574 valine catabolic process(GO:0006574)
0.6 5.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.5 7.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.4 3.0 GO:0003311 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.4 1.3 GO:0016045 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.4 1.7 GO:0010712 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.4 1.6 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.4 8.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.4 2.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.3 6.6 GO:0032438 melanosome organization(GO:0032438)
0.3 4.5 GO:0016199 axon midline choice point recognition(GO:0016199)
0.3 2.2 GO:0021982 pineal gland development(GO:0021982)
0.3 5.3 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.3 1.2 GO:0030497 fatty acid elongation(GO:0030497)
0.3 2.8 GO:0045444 fat cell differentiation(GO:0045444)
0.3 1.7 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.3 2.9 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.3 1.3 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.3 5.6 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.2 11.0 GO:0019226 transmission of nerve impulse(GO:0019226)
0.2 3.5 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.2 2.1 GO:0046548 retinal rod cell development(GO:0046548)
0.2 1.7 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.2 2.0 GO:0061621 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 2.6 GO:0009086 methionine biosynthetic process(GO:0009086)
0.2 1.4 GO:0043090 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.2 1.0 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.2 0.8 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 6.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 5.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 4.8 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 7.1 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.1 5.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 5.9 GO:0036269 swimming behavior(GO:0036269)
0.1 2.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 4.7 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 5.2 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.9 GO:0070475 rRNA base methylation(GO:0070475)
0.1 2.8 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 2.1 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 3.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.9 GO:0009408 response to heat(GO:0009408)
0.1 0.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 1.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.8 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 4.3 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 2.2 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 1.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 3.3 GO:0051781 positive regulation of cell division(GO:0051781)
0.1 12.1 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 2.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 4.8 GO:0007626 locomotory behavior(GO:0007626)
0.0 1.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.6 GO:0000266 mitochondrial fission(GO:0000266)
0.0 2.3 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 1.1 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.9 GO:0051180 vitamin transport(GO:0051180)
0.0 5.1 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 6.1 GO:0006260 DNA replication(GO:0006260)
0.0 6.8 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.8 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 2.3 GO:0003341 cilium movement(GO:0003341)
0.0 1.1 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 8.8 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 1.0 GO:0010842 retina layer formation(GO:0010842)
0.0 1.8 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0038007 anterior/posterior axon guidance(GO:0033564) netrin-activated signaling pathway(GO:0038007)
0.0 1.6 GO:0021782 glial cell development(GO:0021782)
0.0 1.9 GO:0000209 protein polyubiquitination(GO:0000209)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 17.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.6 7.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.5 5.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.3 5.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 6.8 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.3 1.7 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.3 1.0 GO:0043073 germ cell nucleus(GO:0043073)
0.2 35.9 GO:0099572 postsynaptic specialization(GO:0099572)
0.2 1.5 GO:0035517 PR-DUB complex(GO:0035517)
0.2 2.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 6.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 7.5 GO:0030426 growth cone(GO:0030426)
0.1 4.3 GO:0016605 PML body(GO:0016605)
0.1 4.8 GO:0008305 integrin complex(GO:0008305)
0.1 2.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 2.3 GO:0000145 exocyst(GO:0000145)
0.1 2.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 6.6 GO:0031514 motile cilium(GO:0031514)
0.1 2.7 GO:0043204 perikaryon(GO:0043204)
0.1 5.5 GO:0043025 neuronal cell body(GO:0043025)
0.1 10.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 5.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.2 GO:0031430 M band(GO:0031430)
0.1 3.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 2.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 54.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 10.6 GO:0043005 neuron projection(GO:0043005)
0.0 1.4 GO:0016342 catenin complex(GO:0016342)
0.0 2.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 7.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.4 GO:0034399 nuclear periphery(GO:0034399)
0.0 1.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 16.3 GO:0005615 extracellular space(GO:0005615)
0.0 6.8 GO:0005768 endosome(GO:0005768)
0.0 0.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.9 3.6 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.8 2.4 GO:0004990 oxytocin receptor activity(GO:0004990)
0.7 5.8 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.7 18.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.7 4.7 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.6 3.9 GO:0015182 L-histidine transmembrane transporter activity(GO:0005290) L-asparagine transmembrane transporter activity(GO:0015182)
0.6 3.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.6 2.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.5 2.7 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.4 1.3 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.4 12.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.4 3.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.4 8.1 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.4 5.6 GO:2001069 glycogen binding(GO:2001069)
0.4 3.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.3 0.9 GO:0005499 vitamin D binding(GO:0005499)
0.3 7.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 1.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.3 0.9 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.3 1.2 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.3 2.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 6.8 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.3 2.6 GO:0008172 S-methyltransferase activity(GO:0008172)
0.2 1.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 1.6 GO:0070698 type I activin receptor binding(GO:0070698)
0.2 5.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 1.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 2.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 20.1 GO:0030276 clathrin binding(GO:0030276)
0.2 1.9 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 4.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.2 3.1 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 2.1 GO:0038191 neuropilin binding(GO:0038191)
0.1 6.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 2.7 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.1 2.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 1.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 2.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 4.8 GO:0005178 integrin binding(GO:0005178)
0.1 2.1 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 28.7 GO:0008017 microtubule binding(GO:0008017)
0.1 1.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.1 2.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 5.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.5 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 1.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 2.9 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 6.7 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 4.3 GO:0045296 cadherin binding(GO:0045296)
0.0 7.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 6.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 3.9 GO:0005179 hormone activity(GO:0005179)
0.0 1.3 GO:0071949 FAD binding(GO:0071949)
0.0 4.6 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 8.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.5 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 7.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.2 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 1.6 GO:0004497 monooxygenase activity(GO:0004497)
0.0 1.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3 4.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.3 6.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 4.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 2.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.9 PID P73PATHWAY p73 transcription factor network
0.0 3.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 10.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.7 21.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.4 4.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 2.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 2.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.1 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1 0.6 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 5.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.6 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.1 4.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.9 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis