ISMARA results: nr5a1a+nr5a2+nr5a5

Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation

Downloads

Results for nr5a1a+nr5a2+nr5a5

Z-value: 1.47

Motif logo

Transcription factors associated with nr5a1a+nr5a2+nr5a5

Gene Symbol	Gene ID	Gene Info
nr5a5 NCBI UniProt	ENSDARG00000039116	nuclear receptor subfamily 5, group A, member 5
nr5a2 NCBI UniProt	ENSDARG00000100940	nuclear receptor subfamily 5, group A, member 2
nr5a1a NCBI UniProt	ENSDARG00000103176	nuclear receptor subfamily 5, group A, member 1a

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
nr5a5	dr11_v1_chr3_-_53465223_53465249	0.29	5.3e-03	Click!
nr5a2	dr11_v1_chr22_-_22719440_22719440	0.16	1.2e-01	Click!
nr5a1a	dr11_v1_chr8_-_52871056_52871056	-0.15	1.4e-01	Click!

Activity profile of nr5a1a+nr5a2+nr5a5 motif

Sorted Z-values of nr5a1a+nr5a2+nr5a5 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_-_24289641 Show fit	15.25	ENSDART00000128784 ENSDART00000123565 ENSDART00000141922 ENSDART00000184550 ENSDART00000191469	myh7l NCBI UniProt Show fit	myosin heavy chain 7-like
chr16_+_52512025 Show fit	12.08	ENSDART00000056095	fabp10a NCBI UniProt Show fit	fatty acid binding protein 10a, liver basic
chr22_-_2886937 Show fit	10.90	ENSDART00000063533	aqp12 NCBI UniProt Show fit	aquaporin 12
chr8_-_39739056 Show fit	10.89	ENSDART00000147992	si:ch211-170d8.5 NCBI UniProt Show fit	si:ch211-170d8.5
chr21_-_30658509 Show fit	10.84	ENSDART00000139764	si:dkey-22f5.9 NCBI UniProt Show fit	si:dkey-22f5.9
chr22_+_6293563 Show fit	10.42	ENSDART00000063416	rnasel2 NCBI UniProt Show fit	ribonuclease like 2
chr2_-_22152797 Show fit	9.86	ENSDART00000145188	cyp7a1 NCBI UniProt Show fit	cytochrome P450, family 7, subfamily A, polypeptide 1
chr23_+_25856541 Show fit	9.23	ENSDART00000145426 ENSDART00000028236	hnf4a NCBI UniProt Show fit	hepatocyte nuclear factor 4, alpha
chr22_+_38194151 Show fit	9.19	ENSDART00000121965	cp NCBI UniProt Show fit	ceruloplasmin
chr22_+_7439476 Show fit	8.96	ENSDART00000021594 ENSDART00000063389	zgc:92041 NCBI UniProt Show fit	zgc:92041

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of nr5a1a+nr5a2+nr5a5

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	37.4	GO:0010951	negative regulation of endopeptidase activity(GO:0010951)
1.7	25.2	GO:0001678	cellular glucose homeostasis(GO:0001678)
0.4	20.1	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.7	15.1	GO:0006825	copper ion transport(GO:0006825)
0.2	14.9	GO:0051592	response to calcium ion(GO:0051592)
0.0	13.4	GO:0046777	protein autophosphorylation(GO:0046777)
0.1	13.0	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.2	10.7	GO:0018198	peptidyl-cysteine modification(GO:0018198)
0.1	10.6	GO:0051480	regulation of cytosolic calcium ion concentration(GO:0051480)
0.5	10.4	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)

Showing 1 to 10 of 181 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	93.0	GO:0016021	integral component of membrane(GO:0016021)
0.0	58.9	GO:0005615	extracellular space(GO:0005615)
0.0	18.5	GO:0005739	mitochondrion(GO:0005739)
0.2	13.1	GO:0070469	respiratory chain(GO:0070469)
0.1	12.1	GO:0016459	myosin complex(GO:0016459)
0.0	11.5	GO:0043005	neuron projection(GO:0043005)
0.1	11.3	GO:0005759	mitochondrial matrix(GO:0005759)
0.9	11.1	GO:0042627	chylomicron(GO:0042627)
0.2	10.0	GO:0034707	chloride channel complex(GO:0034707)
0.3	8.4	GO:0098978	glutamatergic synapse(GO:0098978)

Showing 1 to 10 of 69 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	52.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
2.6	15.8	GO:0005536	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.5	15.8	GO:0030165	PDZ domain binding(GO:0030165)
0.1	15.6	GO:0005179	hormone activity(GO:0005179)
0.1	14.4	GO:0004252	serine-type endopeptidase activity(GO:0004252)
1.8	12.6	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
2.0	12.1	GO:0032052	bile acid binding(GO:0032052)
0.1	11.0	GO:0042277	peptide binding(GO:0042277)
0.1	10.7	GO:0003774	motor activity(GO:0003774)
0.1	10.0	GO:0005254	chloride channel activity(GO:0005254)

Showing 1 to 10 of 142 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	34.7	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.1	19.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2	7.3	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.3	7.2	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1	6.6	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.3	5.6	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	5.2	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	4.7	SIG CHEMOTAXIS	Genes related to chemotaxis
0.1	3.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	3.6	PID REELIN PATHWAY	Reelin signaling pathway

Showing 1 to 10 of 24 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	25.0	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.2	12.9	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.6	12.5	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.2	10.5	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
1.4	9.9	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
1.2	8.5	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	8.4	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	7.9	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.8	6.7	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.4	5.6	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway

Showing 1 to 10 of 44 entries

Results for nr5a1a+nr5a2+nr5a5

Z-value: 1.47

Motif logo

Transcription factors associated with nr5a1a+nr5a2+nr5a5

Activity-expression correlation:

Activity profile of nr5a1a+nr5a2+nr5a5 motif

Sorted Z-values of nr5a1a+nr5a2+nr5a5 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of nr5a1a+nr5a2+nr5a5

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: