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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for nrf1

Z-value: 2.78

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Transcription factors associated with nrf1

Gene Symbol Gene ID Gene Info
nrf1
ENSDARG00000000018 nuclear respiratory factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nrf1dr11_v1_chr4_-_15103646_151036960.747.5e-18Click!

Activity profile of nrf1 motif

Sorted Z-values of nrf1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_34801041 26.76 ENSDART00000103043
nsfa
N-ethylmaleimide-sensitive factor a
chr12_-_25916530 25.84 ENSDART00000186386
sncgb
synuclein, gamma b (breast cancer-specific protein 1)
chr23_+_44732863 21.96 ENSDART00000160044
ENSDART00000172268
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr19_-_5254699 20.79 ENSDART00000081951
stx1b
syntaxin 1B
chr14_+_22172047 20.78 ENSDART00000114750
ENSDART00000148259
gabrb2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr6_+_27667359 19.02 ENSDART00000159624
ENSDART00000049177
rab6ba
RAB6B, member RAS oncogene family a
chr19_-_19339285 18.89 ENSDART00000158413
ENSDART00000170479
cspg5b
chondroitin sulfate proteoglycan 5b
chr8_-_14050758 18.64 ENSDART00000133922
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr1_+_53954230 17.47 ENSDART00000037729
ENSDART00000159900
ccsapa
centriole, cilia and spindle-associated protein a
chr2_+_22795494 17.41 ENSDART00000042255
rab6bb
RAB6B, member RAS oncogene family b
chr25_+_21832938 16.56 ENSDART00000148299
ckmt1
creatine kinase, mitochondrial 1
chr2_-_16565690 16.32 ENSDART00000022549
atp1b3a
ATPase Na+/K+ transporting subunit beta 3a
chr7_+_23495986 16.09 ENSDART00000190739
ENSDART00000115299
ENSDART00000101423
ENSDART00000142401
zgc:109889
zgc:109889
chr17_-_36896560 15.94 ENSDART00000045287
mapre3a
microtubule-associated protein, RP/EB family, member 3a
chr20_-_31905968 15.84 ENSDART00000142806
stxbp5a
syntaxin binding protein 5a (tomosyn)
chr16_-_25285469 15.31 ENSDART00000183943
ENSDART00000191103
ENSDART00000154543
prelid3a
PRELI domain containing 3A
chr16_+_5156420 14.75 ENSDART00000012053
elovl4a
ELOVL fatty acid elongase 4a
chr10_-_31782616 14.70 ENSDART00000128839
fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr18_+_17428258 14.53 ENSDART00000010452
zgc:91860
zgc:91860
chr1_+_36436936 14.32 ENSDART00000124112
pou4f2
POU class 4 homeobox 2
chr4_+_6643421 13.94 ENSDART00000099462
gpr85
G protein-coupled receptor 85
chr1_-_26131088 13.76 ENSDART00000193973
ENSDART00000054209
cdkn2a/b
cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4)
chr10_-_15405564 13.46 ENSDART00000020665
sgtb
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr24_+_39129316 13.39 ENSDART00000155346
tbc1d24
TBC1 domain family, member 24
chr13_+_27314795 13.15 ENSDART00000128726
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr11_+_34824099 13.03 ENSDART00000037017
ENSDART00000146944
slc38a3a
solute carrier family 38, member 3a
chr8_-_52413032 12.90 ENSDART00000183039
CABZ01070469.1

chr25_+_21833287 12.66 ENSDART00000187606
ckmt1
creatine kinase, mitochondrial 1
chr16_+_52748263 12.60 ENSDART00000032275
atp6v1c1a
ATPase H+ transporting V1 subunit C1a
chr6_+_27146671 12.45 ENSDART00000156792
kif1aa
kinesin family member 1Aa
chr1_-_9980765 12.40 ENSDART00000142906
si:dkeyp-75b4.7
si:dkeyp-75b4.7
chr22_-_15704704 12.36 ENSDART00000017838
ENSDART00000130238
safb
scaffold attachment factor B
chr14_-_33454595 12.26 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
tmem255a
transmembrane protein 255A
chr6_-_48311 12.22 ENSDART00000131010
zgc:114175
zgc:114175
chr25_+_13791627 12.20 ENSDART00000159278
zgc:92873
zgc:92873
chr20_+_37661229 12.19 ENSDART00000138539
aig1
androgen-induced 1 (H. sapiens)
chr1_-_40227166 12.14 ENSDART00000146680
si:ch211-113e8.3
si:ch211-113e8.3
chr24_+_5840748 12.04 ENSDART00000139191
trpc1
transient receptor potential cation channel, subfamily C, member 1
chr14_+_23970818 11.92 ENSDART00000123338
ENSDART00000124944
kif3a
kinesin family member 3A
chr1_-_45633955 11.86 ENSDART00000044057
sept3
septin 3
chr6_+_41255485 11.69 ENSDART00000042683
ENSDART00000186013
cadpsb
Ca2+-dependent activator protein for secretion b
chr3_-_26341959 11.64 ENSDART00000169344
ENSDART00000142878
ENSDART00000087196
zgc:153240
zgc:153240
chr5_+_24882633 11.53 ENSDART00000111302
rhbdd3
rhomboid domain containing 3
chr9_-_32177117 11.46 ENSDART00000078568
sf3b1
splicing factor 3b, subunit 1
chr20_+_88168 11.38 ENSDART00000149283
zgc:112001
zgc:112001
chr7_+_73593814 11.30 ENSDART00000110544
znf219
zinc finger protein 219
chr22_+_20208185 11.00 ENSDART00000142748
si:dkey-110c1.7
si:dkey-110c1.7
chr24_+_4977862 10.97 ENSDART00000114537
zic4
zic family member 4
chr24_-_8732519 10.84 ENSDART00000082351
tfap2a
transcription factor AP-2 alpha
chr15_-_4415917 10.83 ENSDART00000062874
atp1b3b
ATPase Na+/K+ transporting subunit beta 3b
chr14_-_25577094 10.81 ENSDART00000163669
cplx2
complexin 2
chr19_-_28367413 10.78 ENSDART00000079092
si:dkey-261i16.5
si:dkey-261i16.5
chr8_+_18624658 10.59 ENSDART00000089141
fsd1
fibronectin type III and SPRY domain containing 1
chr9_+_30108641 10.47 ENSDART00000060174
jagn1a
jagunal homolog 1a
chr18_-_19491162 10.39 ENSDART00000090413
snapc5
small nuclear RNA activating complex, polypeptide 5
chr23_+_2752645 10.33 ENSDART00000146475
top1
DNA topoisomerase I
chr19_-_15397946 10.25 ENSDART00000143480
hivep3a
human immunodeficiency virus type I enhancer binding protein 3a
chr23_-_12345764 10.23 ENSDART00000133956
phactr3a
phosphatase and actin regulator 3a
chr18_-_1228688 10.20 ENSDART00000064403
nptnb
neuroplastin b
chr18_+_17428506 10.19 ENSDART00000100223
zgc:91860
zgc:91860
chr24_+_35911300 10.16 ENSDART00000129679
abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr19_-_10243148 10.09 ENSDART00000148073
shisa7b
shisa family member 7
chr13_-_23756700 10.06 ENSDART00000057612
rgs17
regulator of G protein signaling 17
chr25_-_36282539 10.06 ENSDART00000073398
slc7a10b
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10b
chr21_+_45733871 10.02 ENSDART00000187285
ENSDART00000193018
zgc:77058
zgc:77058
chr18_+_28988373 9.98 ENSDART00000018685
syt9a
synaptotagmin IXa
chr24_-_24849091 9.96 ENSDART00000133649
ENSDART00000038290
crhb
corticotropin releasing hormone b
chr6_-_27057702 9.92 ENSDART00000149363
stk25a
serine/threonine kinase 25a
chr5_+_21144269 9.87 ENSDART00000028087
cds2
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr4_-_1497384 9.77 ENSDART00000093236
zmp:0000000711
zmp:0000000711
chr22_-_22416337 9.64 ENSDART00000142947
ENSDART00000089569
camsap2a
calmodulin regulated spectrin-associated protein family, member 2a
chr23_+_43794687 9.62 ENSDART00000149740
si:ch211-149b19.2
si:ch211-149b19.2
chr24_+_35911020 9.46 ENSDART00000088480
abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr6_-_38418862 9.45 ENSDART00000104135
gabra5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr2_-_24996441 9.30 ENSDART00000144795
slc35g2a
solute carrier family 35, member G2a
chr24_+_5840258 9.22 ENSDART00000087034
trpc1
transient receptor potential cation channel, subfamily C, member 1
chr16_+_46430627 9.15 ENSDART00000127681
rpz6
rapunzel 6
chr11_+_2763168 9.12 ENSDART00000042972
srpk1b
SRSF protein kinase 1b
chr1_-_16507812 9.08 ENSDART00000169081
mtmr7b
myotubularin related protein 7b
chr6_+_12853655 9.05 ENSDART00000156341
fam117ba
family with sequence similarity 117, member Ba
chr14_+_14225048 9.05 ENSDART00000168749
nlgn3a
neuroligin 3a
chr15_+_16886196 9.03 ENSDART00000139296
ENSDART00000049196
gdpd1
glycerophosphodiester phosphodiesterase domain containing 1
chr6_-_38419318 8.99 ENSDART00000138026
gabra5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr7_+_48288762 8.95 ENSDART00000083569
oaz2b
ornithine decarboxylase antizyme 2b
chr24_+_4978055 8.94 ENSDART00000045813
zic4
zic family member 4
chr13_+_36622100 8.90 ENSDART00000133198
si:ch211-67f24.7
si:ch211-67f24.7
chr18_-_5692292 8.90 ENSDART00000121503
cplx3b
complexin 3b
chr18_-_898870 8.86 ENSDART00000151777
ENSDART00000062654
parp6a
poly (ADP-ribose) polymerase family, member 6a
chr25_+_14165447 8.84 ENSDART00000145387
shank2
SH3 and multiple ankyrin repeat domains 2
chr17_-_11329959 8.78 ENSDART00000015418
irf2bpl
interferon regulatory factor 2 binding protein-like
chr2_-_3678029 8.74 ENSDART00000146861
mmp16b
matrix metallopeptidase 16b (membrane-inserted)
chr10_+_18952271 8.58 ENSDART00000146517
dpysl2b
dihydropyrimidinase-like 2b
chr5_-_32445835 8.48 ENSDART00000170919
ncs1a
neuronal calcium sensor 1a
chr21_-_43606502 8.44 ENSDART00000151030
si:ch73-362m14.4
si:ch73-362m14.4
chr10_-_17170086 8.31 ENSDART00000020122
ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr21_+_18313152 8.31 ENSDART00000170510
si:ch73-287m6.1
si:ch73-287m6.1
chr7_-_49594995 8.30 ENSDART00000174161
ENSDART00000109147
brsk2b
BR serine/threonine kinase 2b
chr18_+_9615147 8.26 ENSDART00000160284
pclob
piccolo presynaptic cytomatrix protein b
chr10_+_44584614 8.25 ENSDART00000163523
sez6l
seizure related 6 homolog (mouse)-like
chr4_-_4780667 8.20 ENSDART00000133973
si:ch211-258f14.2
si:ch211-258f14.2
chr24_-_21172122 8.11 ENSDART00000154259
atp6v1ab
ATPase H+ transporting V1 subunit Ab
chr1_-_25438737 8.10 ENSDART00000134470
fhdc1
FH2 domain containing 1
chr18_+_41495841 8.10 ENSDART00000098671
si:ch211-203b8.6
si:ch211-203b8.6
chr14_-_2221877 8.09 ENSDART00000106704
pcdh2ab1
protocadherin 2 alpha b 1
chr4_-_5018705 7.99 ENSDART00000154025
strip2
striatin interacting protein 2
chr15_+_21252532 7.90 ENSDART00000162619
ENSDART00000019636
ENSDART00000144901
ENSDART00000138676
ENSDART00000133821
ENSDART00000146967
ENSDART00000143990
ENSDART00000142070
ENSDART00000132373
usf1
upstream transcription factor 1
chr9_-_24209083 7.88 ENSDART00000134599
zgc:153521
zgc:153521
chr15_+_19915345 7.82 ENSDART00000114267
map6b
microtubule-associated protein 6b
chr20_+_1121458 7.82 ENSDART00000064472
pnrc1
proline-rich nuclear receptor coactivator 1
chr9_+_53276356 7.77 ENSDART00000003310
sox21b
SRY (sex determining region Y)-box 21b
chr5_+_1278092 7.76 ENSDART00000147972
ENSDART00000159783
dnm1a
dynamin 1a
chr22_-_372723 7.74 ENSDART00000112895
FNDC10
si:zfos-1324h11.5
chr13_+_159504 7.72 ENSDART00000057248
ewsr1b
EWS RNA-binding protein 1b
chr7_-_51546386 7.68 ENSDART00000174306
nhsl2
NHS-like 2
chr15_-_45538773 7.65 ENSDART00000113494
MB21D2
Mab-21 domain containing 2
chr5_+_41793001 7.53 ENSDART00000136439
ENSDART00000190477
ENSDART00000192289
bcl7a
BCL tumor suppressor 7A
chr11_+_25044082 7.45 ENSDART00000123263
phf20a
PHD finger protein 20, a
chr21_+_42226113 7.44 ENSDART00000170362
GABRB2 (1 of many)
gamma-aminobutyric acid type A receptor beta2 subunit
chr24_+_37722048 7.43 ENSDART00000191918
rab11fip3
RAB11 family interacting protein 3 (class II)
chr7_-_39203799 7.41 ENSDART00000173727
chrm4a
cholinergic receptor, muscarinic 4a
chr21_+_18275961 7.40 ENSDART00000019750
wdr5
WD repeat domain 5
chr17_-_33716688 7.39 ENSDART00000043651
dnal1
dynein, axonemal, light chain 1
chr14_-_24277805 7.39 ENSDART00000054243
dpf2l
D4, zinc and double PHD fingers family 2, like
chr3_+_51563695 7.38 ENSDART00000008607
ttyh2l
tweety homolog 2, like
chr7_-_38340674 7.37 ENSDART00000075782
slc7a10a
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10a
chr16_+_12632428 7.31 ENSDART00000184600
ENSDART00000180537
nat14
N-acetyltransferase 14 (GCN5-related, putative)
chr9_+_34380299 7.30 ENSDART00000131705
lamp1
lysosomal-associated membrane protein 1
chr12_-_13966184 7.28 ENSDART00000066368
klhl11
kelch-like family member 11
chr24_-_22702017 7.26 ENSDART00000179403
ctnnd2a
catenin (cadherin-associated protein), delta 2a
chr14_+_24277556 7.20 ENSDART00000122660
hnrnpa0a
heterogeneous nuclear ribonucleoprotein A0a
chr1_-_53407448 7.17 ENSDART00000160033
ENSDART00000172322
elmod2
ELMO/CED-12 domain containing 2
chr16_-_52540056 7.16 ENSDART00000188304
CR293507.1

chr1_-_25438934 7.04 ENSDART00000111686
fhdc1
FH2 domain containing 1
chr6_-_8392104 7.02 ENSDART00000081561
ENSDART00000181178
ilf3a
interleukin enhancer binding factor 3a
chr6_-_12900154 7.02 ENSDART00000080408
ENSDART00000150887
ical1
islet cell autoantigen 1-like
chr10_-_40939706 6.90 ENSDART00000059795
ENSDART00000190510
bmp1b
bone morphogenetic protein 1b
chr21_-_14878220 6.87 ENSDART00000131237
ulk1b
unc-51 like autophagy activating kinase 1
chr6_+_4539953 6.76 ENSDART00000025031
pou4f1
POU class 4 homeobox 1
chr8_-_25120231 6.74 ENSDART00000147308
amigo1
adhesion molecule with Ig-like domain 1
chr4_-_9810999 6.73 ENSDART00000146858
si:dkeyp-27e10.3
si:dkeyp-27e10.3
chr2_+_26682913 6.62 ENSDART00000010683
ENSDART00000131411
ENSDART00000137933
impa1
inositol monophosphatase 1
chr11_-_30352333 6.60 ENSDART00000030794
tmem169a
transmembrane protein 169a
chr7_+_61906903 6.49 ENSDART00000108540
tdrd7b
tudor domain containing 7 b
chr16_-_33097398 6.37 ENSDART00000166617
dopey1
dopey family member 1
chr19_+_20787179 6.37 ENSDART00000193204
adnp2b
ADNP homeobox 2b
chr6_-_19340889 6.28 ENSDART00000181407
mif4gda
MIF4G domain containing a
chr17_-_22067451 6.27 ENSDART00000156872
ttbk1b
tau tubulin kinase 1b
chr20_+_37661547 6.19 ENSDART00000007253
aig1
androgen-induced 1 (H. sapiens)
chr2_-_32558795 6.17 ENSDART00000140026
smarcd3a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr11_+_34824262 6.15 ENSDART00000103157
slc38a3a
solute carrier family 38, member 3a
chr16_-_23379464 6.15 ENSDART00000045891
trim46a
tripartite motif containing 46a
chr5_-_41142467 6.11 ENSDART00000129415
zfr
zinc finger RNA binding protein
chr10_-_7988396 6.07 ENSDART00000141445
ENSDART00000024282
ewsr1a
EWS RNA-binding protein 1a
chr13_+_45485185 6.06 ENSDART00000134730
ENSDART00000019774
ENSDART00000142381
tmem50a
transmembrane protein 50A
chr1_-_46401385 6.03 ENSDART00000150029
atp11a
ATPase phospholipid transporting 11A
chr5_-_33460959 6.03 ENSDART00000085636
si:ch211-182d3.1
si:ch211-182d3.1
chr5_-_41142768 5.99 ENSDART00000074789
zfr
zinc finger RNA binding protein
chr12_+_27022517 5.99 ENSDART00000152975
msl1b
male-specific lethal 1 homolog b (Drosophila)
chr25_+_3677650 5.99 ENSDART00000154348
prnprs3
prion protein, related sequence 3
chr9_+_38163876 5.98 ENSDART00000137955
clasp1a
cytoplasmic linker associated protein 1a
chr8_+_7875110 5.95 ENSDART00000167423
ENSDART00000160267
ENSDART00000180490
mbd1a
methyl-CpG binding domain protein 1a
chr13_-_15793585 5.94 ENSDART00000145914
ENSDART00000010286
bag5
BCL2 associated athanogene 5
chr5_-_19932621 5.90 ENSDART00000088881
git2a
G protein-coupled receptor kinase interacting ArfGAP 2a
chr5_+_62319217 5.88 ENSDART00000050879
pho
phoenix
chr11_+_18873113 5.86 ENSDART00000103969
ENSDART00000103968
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr22_+_25049563 5.85 ENSDART00000078173
dzank1
double zinc ribbon and ankyrin repeat domains 1
chr4_+_9394426 5.80 ENSDART00000092013
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr17_+_24632440 5.76 ENSDART00000157092
map4k3b
mitogen-activated protein kinase kinase kinase kinase 3b
chr23_+_29569893 5.75 ENSDART00000078304
lzic
leucine zipper and CTNNBIP1 domain containing
chr21_-_4764120 5.73 ENSDART00000129355
ENSDART00000102643
camsap1a
calmodulin regulated spectrin-associated protein 1a
chr25_-_20666328 5.68 ENSDART00000098076
csk
C-terminal Src kinase
chr2_-_30770736 5.67 ENSDART00000131230
rgs20
regulator of G protein signaling 20
chr8_+_34624025 5.66 ENSDART00000180772
BX247865.2

chr22_+_1560991 5.63 ENSDART00000190639
AL954741.4

chr8_+_34720244 5.54 ENSDART00000181958
ENSDART00000189806
ENSDART00000190167
ENSDART00000183165
zgc:174461
zgc:174461
chr15_+_38221196 5.53 ENSDART00000122134
ENSDART00000190099
stim1a
stromal interaction molecule 1a
chr24_-_20956781 5.51 ENSDART00000142080
kpna1
karyopherin alpha 1 (importin alpha 5)
chr25_+_26895962 5.49 ENSDART00000191254
ENSDART00000098307
znf800a
zinc finger protein 800a
chr12_+_28854410 5.48 ENSDART00000152991
nfe2l1b
nuclear factor, erythroid 2-like 1b
chr17_+_33719415 5.47 ENSDART00000132294
fut8a
fucosyltransferase 8a (alpha (1,6) fucosyltransferase)
chr7_-_65093209 5.47 ENSDART00000060545
ENSDART00000192447
dennd5a
DENN/MADD domain containing 5A
chr14_+_597532 5.47 ENSDART00000159805
LO018568.2

chr14_+_10656975 5.46 ENSDART00000127594
ENSDART00000125865
atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr3_+_32681274 5.40 ENSDART00000140290
ENSDART00000164428
kat8
K(lysine) acetyltransferase 8
chr5_+_36611128 5.33 ENSDART00000097684
nova1
neuro-oncological ventral antigen 1
chr13_+_18366299 5.32 ENSDART00000133057
ccar1
cell division cycle and apoptosis regulator 1
chr13_+_12299997 5.32 ENSDART00000108535
gabrb1
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr3_-_50118140 5.29 ENSDART00000131913
hgs
hepatocyte growth factor-regulated tyrosine kinase substrate
chr14_-_1949277 5.27 ENSDART00000159435
pcdh2g5
protocadherin 2 gamma 5
chr9_-_16853462 5.25 ENSDART00000160273
CT573248.2

chr24_-_24118451 5.24 ENSDART00000111096
zgc:112982
zgc:112982
chr14_+_14224730 5.23 ENSDART00000180112
ENSDART00000184891
ENSDART00000174760
nlgn3a
neuroligin 3a
chr8_-_34427364 5.21 ENSDART00000112854
ENSDART00000161282
ENSDART00000113230
gapvd1
GTPase activating protein and VPS9 domains 1
chr18_+_18982077 5.20 ENSDART00000006300
hacd3
3-hydroxyacyl-CoA dehydratase 3
chr25_+_388258 5.12 ENSDART00000166834
rfx7b
regulatory factor X7b
chr16_+_32051572 5.11 ENSDART00000039109
leng1
leukocyte receptor cluster (LRC) member 1
chr21_+_11521163 5.10 ENSDART00000139267
zgc:114104
zgc:114104
chr18_+_36601556 5.08 ENSDART00000127825
clasrp
CLK4-associating serine/arginine rich protein
chr5_-_31035198 5.00 ENSDART00000086534
cyb5d2
cytochrome b5 domain containing 2
chr11_-_44037692 4.99 ENSDART00000186333
FP016005.2

Network of associatons between targets according to the STRING database.

First level regulatory network of nrf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.9 31.5 GO:0048211 Golgi vesicle docking(GO:0048211)
5.8 17.4 GO:0042942 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
4.8 19.2 GO:0006867 asparagine transport(GO:0006867)
4.5 13.5 GO:1903332 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
3.5 10.5 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
3.4 16.8 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
3.3 16.6 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
3.3 10.0 GO:0035902 response to immobilization stress(GO:0035902)
3.3 19.6 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
2.8 19.9 GO:0021534 cell proliferation in hindbrain(GO:0021534)
2.6 49.1 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
2.5 17.5 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
2.3 9.0 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
2.1 10.6 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
1.9 18.9 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
1.8 11.0 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
1.8 23.2 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
1.8 16.0 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
1.7 8.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
1.7 5.1 GO:0001207 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
1.7 11.7 GO:1990504 dense core granule exocytosis(GO:1990504)
1.7 5.0 GO:0098838 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
1.6 24.5 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.5 6.1 GO:0061181 regulation of chondrocyte development(GO:0061181)
1.5 10.4 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
1.5 17.6 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
1.5 13.2 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
1.4 4.1 GO:2000402 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
1.3 14.3 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
1.3 3.8 GO:0046048 ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
1.3 3.8 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
1.2 6.0 GO:0021731 trigeminal motor nucleus development(GO:0021731)
1.1 10.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.1 35.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
1.1 4.4 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
1.1 9.9 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
1.0 25.8 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.9 3.7 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.9 4.4 GO:0010939 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.9 7.8 GO:1901985 positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.9 9.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.8 21.2 GO:0030497 fatty acid elongation(GO:0030497)
0.8 19.3 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.8 8.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.8 4.9 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.8 14.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.8 4.8 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.8 2.4 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.8 11.9 GO:0008089 anterograde axonal transport(GO:0008089)
0.7 2.2 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.7 2.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.7 12.9 GO:0098926 postsynaptic signal transduction(GO:0098926)
0.7 19.0 GO:0006828 manganese ion transport(GO:0006828)
0.7 9.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.7 4.8 GO:0007589 body fluid secretion(GO:0007589)
0.7 2.7 GO:0006272 leading strand elongation(GO:0006272)
0.6 1.9 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
0.6 6.4 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.6 4.9 GO:0051013 microtubule severing(GO:0051013)
0.6 3.1 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.6 7.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.6 10.8 GO:0072160 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.6 2.4 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.6 6.0 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.6 4.2 GO:0043931 ossification involved in bone maturation(GO:0043931) bone maturation(GO:0070977)
0.5 1.6 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.5 4.4 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.5 4.3 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.5 8.0 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.5 3.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.5 6.6 GO:0006020 inositol metabolic process(GO:0006020)
0.5 3.9 GO:0021592 fourth ventricle development(GO:0021592)
0.5 8.6 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.4 4.5 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.4 8.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.4 2.6 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.4 10.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.4 2.1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.4 20.0 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.4 2.4 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.4 10.8 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.4 9.1 GO:0007413 axonal fasciculation(GO:0007413)
0.4 15.8 GO:0050708 regulation of protein secretion(GO:0050708)
0.4 11.0 GO:0006446 regulation of translational initiation(GO:0006446)
0.4 7.3 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.4 4.6 GO:0090398 cellular senescence(GO:0090398)
0.4 3.4 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.4 8.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.4 10.2 GO:0070593 dendrite self-avoidance(GO:0070593)
0.4 8.9 GO:0006595 polyamine metabolic process(GO:0006595)
0.4 5.6 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.4 8.5 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.4 12.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.3 3.1 GO:0006465 signal peptide processing(GO:0006465)
0.3 5.9 GO:1990399 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.3 5.5 GO:0036065 fucosylation(GO:0036065)
0.3 2.7 GO:0090660 cerebrospinal fluid circulation(GO:0090660)
0.3 21.3 GO:0015914 phospholipid transport(GO:0015914)
0.3 1.3 GO:0090113 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.3 0.9 GO:0060760 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.3 1.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.3 2.0 GO:0031646 positive regulation of myelination(GO:0031643) positive regulation of neurological system process(GO:0031646)
0.3 1.4 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.3 6.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.3 4.2 GO:0090481 nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.3 1.4 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.3 2.2 GO:0008343 adult feeding behavior(GO:0008343)
0.3 6.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.3 11.9 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.3 8.7 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.3 3.6 GO:0070286 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285) axonemal dynein complex assembly(GO:0070286)
0.3 13.8 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.2 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 7.0 GO:0016925 protein sumoylation(GO:0016925)
0.2 2.8 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 3.0 GO:0046599 regulation of centriole replication(GO:0046599)
0.2 18.6 GO:0016573 histone acetylation(GO:0016573)
0.2 3.4 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.2 2.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 0.6 GO:0070417 cellular response to cold(GO:0070417)
0.2 3.6 GO:0070828 heterochromatin organization(GO:0070828)
0.2 1.2 GO:0006013 mannose metabolic process(GO:0006013)
0.2 13.8 GO:0021954 central nervous system neuron development(GO:0021954)
0.2 0.4 GO:0098773 skin epidermis development(GO:0098773)
0.2 4.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.2 1.9 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.2 1.9 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.2 4.2 GO:0009408 response to heat(GO:0009408)
0.2 29.1 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.2 1.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2 2.8 GO:0099590 positive regulation of synaptic transmission, glutamatergic(GO:0051968) neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943) neurotransmitter receptor internalization(GO:0099590)
0.2 0.5 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 6.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.2 1.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 3.2 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.2 5.4 GO:0016180 snRNA processing(GO:0016180)
0.2 4.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 3.6 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.2 0.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.2 3.7 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.2 1.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.2 0.9 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 8.0 GO:0003401 axis elongation(GO:0003401)
0.2 2.7 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 4.0 GO:0060030 dorsal convergence(GO:0060030)
0.1 2.1 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.1 3.0 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 1.3 GO:0034982 mitochondrial protein processing(GO:0034982)
0.1 5.8 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 4.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 3.8 GO:0008643 carbohydrate transport(GO:0008643)
0.1 1.0 GO:0018026 peptidyl-lysine monomethylation(GO:0018026) peptidyl-lysine dimethylation(GO:0018027)
0.1 1.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 4.9 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.6 GO:0051103 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.1 5.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 1.3 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 14.2 GO:0050684 regulation of mRNA processing(GO:0050684)
0.1 3.3 GO:0043171 peptide catabolic process(GO:0043171)
0.1 18.6 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 2.6 GO:0003323 type B pancreatic cell development(GO:0003323)
0.1 3.9 GO:0048634 regulation of muscle organ development(GO:0048634)
0.1 1.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 3.6 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.1 3.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 3.6 GO:0048813 dendrite morphogenesis(GO:0048813)
0.1 12.3 GO:0006821 chloride transport(GO:0006821)
0.1 1.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.6 GO:2000047 cell-cell adhesion mediated by cadherin(GO:0044331) regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.1 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.9 GO:0006611 protein export from nucleus(GO:0006611)
0.1 6.0 GO:0006414 translational elongation(GO:0006414)
0.1 5.9 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.1 7.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 4.6 GO:0030336 negative regulation of cell migration(GO:0030336)
0.1 6.3 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.1 6.4 GO:0030903 notochord development(GO:0030903)
0.1 2.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 1.5 GO:0043153 entrainment of circadian clock(GO:0009649) entrainment of circadian clock by photoperiod(GO:0043153)
0.1 6.2 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.1 3.4 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 23.4 GO:0043087 regulation of GTPase activity(GO:0043087)
0.1 1.2 GO:0006265 DNA topological change(GO:0006265)
0.1 3.9 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 14.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 3.4 GO:0017157 regulation of exocytosis(GO:0017157)
0.1 2.0 GO:0061512 protein localization to cilium(GO:0061512)
0.1 1.2 GO:0071230 response to amino acid(GO:0043200) cellular response to amino acid stimulus(GO:0071230)
0.1 1.7 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 2.1 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.1 4.2 GO:0042552 myelination(GO:0042552)
0.1 2.2 GO:0050770 regulation of axonogenesis(GO:0050770)
0.1 6.9 GO:0048675 axon extension(GO:0048675)
0.1 7.3 GO:0007219 Notch signaling pathway(GO:0007219)
0.1 3.2 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.1 1.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 2.3 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.1 1.5 GO:0021545 cranial nerve development(GO:0021545)
0.0 0.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 1.1 GO:0090307 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 2.7 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 3.3 GO:0007030 Golgi organization(GO:0007030)
0.0 1.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 5.4 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.7 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.4 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 2.4 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 2.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.9 GO:0031398 positive regulation of protein ubiquitination(GO:0031398) positive regulation of protein modification by small protein conjugation or removal(GO:1903322)
0.0 0.8 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.6 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 4.8 GO:0000377 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.1 GO:0036503 ERAD pathway(GO:0036503)
0.0 3.7 GO:0006874 cellular calcium ion homeostasis(GO:0006874)
0.0 1.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.4 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.4 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 1.0 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.3 GO:0048844 artery morphogenesis(GO:0048844)
0.0 2.3 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.6 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.3 GO:0036297 interstrand cross-link repair(GO:0036297)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 49.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
4.5 13.5 GO:0072380 TRC complex(GO:0072380)
2.0 6.0 GO:0005828 kinetochore microtubule(GO:0005828)
1.8 12.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
1.8 17.6 GO:0036449 microtubule minus-end(GO:0036449)
1.6 4.9 GO:0008352 katanin complex(GO:0008352)
1.5 24.5 GO:0031209 SCAR complex(GO:0031209)
1.4 11.4 GO:0072487 MSL complex(GO:0072487)
1.4 8.5 GO:0008385 IkappaB kinase complex(GO:0008385)
1.4 56.5 GO:0043679 axon terminus(GO:0043679)
1.1 4.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
1.1 16.9 GO:0071564 npBAF complex(GO:0071564)
0.9 7.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.8 10.0 GO:0031045 dense core granule(GO:0031045)
0.8 8.3 GO:0098982 GABA-ergic synapse(GO:0098982)
0.8 2.5 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.8 12.2 GO:0044545 NSL complex(GO:0044545)
0.8 3.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.7 6.3 GO:0089701 U2AF(GO:0089701)
0.7 23.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.7 6.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.6 3.8 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.6 10.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.6 6.2 GO:0071565 nBAF complex(GO:0071565)
0.6 16.0 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.6 4.8 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.6 21.5 GO:0035869 ciliary transition zone(GO:0035869)
0.6 4.7 GO:0071914 prominosome(GO:0071914)
0.6 10.5 GO:0005801 cis-Golgi network(GO:0005801)
0.6 11.9 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.6 4.5 GO:0034464 BBSome(GO:0034464)
0.5 11.2 GO:0070822 Sin3-type complex(GO:0070822)
0.5 2.0 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.5 11.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.5 3.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.5 2.9 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.5 20.3 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.5 5.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.5 4.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.5 3.7 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.4 8.3 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.4 7.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.4 2.1 GO:0055087 Ski complex(GO:0055087)
0.4 1.2 GO:0097361 CIA complex(GO:0097361)
0.4 5.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.4 36.9 GO:0005795 Golgi stack(GO:0005795)
0.4 4.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.4 11.7 GO:0098978 glutamatergic synapse(GO:0098978)
0.4 3.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.3 1.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.3 2.4 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.3 26.6 GO:0005871 kinesin complex(GO:0005871)
0.3 4.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.3 12.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3 2.8 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.3 7.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.3 1.9 GO:0071818 BAT3 complex(GO:0071818)
0.3 0.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 11.0 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.3 1.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.3 5.4 GO:0032039 integrator complex(GO:0032039)
0.2 3.1 GO:0070461 SAGA-type complex(GO:0070461)
0.2 10.2 GO:0030286 dynein complex(GO:0030286)
0.2 3.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 7.4 GO:0034707 chloride channel complex(GO:0034707)
0.2 2.0 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 1.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 1.2 GO:0071986 Ragulator complex(GO:0071986)
0.2 1.6 GO:0032797 SMN complex(GO:0032797)
0.2 2.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 1.4 GO:0070847 core mediator complex(GO:0070847)
0.2 0.5 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.2 6.3 GO:0042734 presynaptic membrane(GO:0042734)
0.2 1.5 GO:0016272 prefoldin complex(GO:0016272)
0.2 6.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.2 2.3 GO:0048179 activin receptor complex(GO:0048179)
0.2 2.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 21.5 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.1 0.9 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.1 21.5 GO:0034703 cation channel complex(GO:0034703)
0.1 2.0 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 2.1 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.1 1.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 25.0 GO:0030424 axon(GO:0030424)
0.1 10.8 GO:0014069 postsynaptic density(GO:0014069)
0.1 5.2 GO:0016592 mediator complex(GO:0016592)
0.1 1.1 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.1 14.4 GO:0005769 early endosome(GO:0005769)
0.1 3.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 4.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 10.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 0.5 GO:0030904 retromer complex(GO:0030904)
0.1 6.3 GO:0000786 nucleosome(GO:0000786)
0.1 5.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 3.9 GO:0005814 centriole(GO:0005814)
0.1 1.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 44.4 GO:0005794 Golgi apparatus(GO:0005794)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.6 GO:0035770 ribonucleoprotein granule(GO:0035770)
0.0 44.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 3.3 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.3 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 3.0 GO:0043235 receptor complex(GO:0043235)
0.0 5.3 GO:0005929 cilium(GO:0005929)
0.0 5.7 GO:0005764 lysosome(GO:0005764)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 4.7 GO:0097708 cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 25.8 GO:1903136 cuprous ion binding(GO:1903136)
3.2 19.2 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290) L-asparagine transmembrane transporter activity(GO:0015182)
2.7 24.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
2.5 9.9 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
2.5 49.1 GO:0001671 ATPase activator activity(GO:0001671)
2.2 8.9 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
2.2 6.6 GO:0052833 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
2.2 15.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
2.1 8.5 GO:0008384 IkappaB kinase activity(GO:0008384)
1.8 23.2 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
1.7 5.0 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
1.6 4.8 GO:1901612 phosphatidic acid binding(GO:0070300) phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
1.4 4.1 GO:0048487 beta-tubulin binding(GO:0048487)
1.4 17.6 GO:0030507 spectrin binding(GO:0030507)
1.3 18.4 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
1.3 5.2 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
1.2 11.0 GO:0008494 translation activator activity(GO:0008494)
1.1 4.6 GO:0019948 SUMO activating enzyme activity(GO:0019948)
1.1 12.7 GO:0043014 alpha-tubulin binding(GO:0043014)
1.1 6.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
1.0 3.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.9 15.8 GO:0045159 myosin II binding(GO:0045159)
0.9 3.7 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.8 3.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.8 19.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.8 7.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.8 2.4 GO:1990715 mRNA CDS binding(GO:1990715)
0.8 16.0 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.7 10.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.7 8.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.7 17.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.7 7.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.7 6.0 GO:0043515 kinetochore binding(GO:0043515)
0.7 10.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.6 18.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.6 4.4 GO:0016972 thiol oxidase activity(GO:0016972)
0.6 6.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.6 2.4 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.6 5.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.6 2.4 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.6 7.7 GO:0045503 dynein light chain binding(GO:0045503)
0.6 5.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.6 5.6 GO:0035198 miRNA binding(GO:0035198)
0.6 22.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.5 5.4 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.5 2.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.5 16.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.5 8.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.5 2.3 GO:0050699 WW domain binding(GO:0050699)
0.5 9.0 GO:0004622 lysophospholipase activity(GO:0004622)
0.4 25.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.4 3.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.4 14.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.4 10.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.4 5.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.4 3.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.4 8.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.4 3.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.4 8.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.4 2.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.4 1.4 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.4 11.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.4 1.1 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.3 2.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.3 2.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 6.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3 9.1 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.3 5.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.3 8.3 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.3 4.3 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.3 1.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.3 4.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.3 9.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 2.5 GO:0030332 cyclin binding(GO:0030332)
0.2 10.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 4.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 1.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 4.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.2 1.9 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.2 0.9 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.2 10.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 7.7 GO:0035064 methylated histone binding(GO:0035064)
0.2 1.8 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 3.8 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.2 3.8 GO:0015149 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.2 3.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 4.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2 90.6 GO:0003924 GTPase activity(GO:0003924)
0.2 4.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 5.9 GO:0051087 chaperone binding(GO:0051087)
0.2 0.6 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 0.6 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.2 3.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 1.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 4.5 GO:0031267 small GTPase binding(GO:0031267)
0.2 1.5 GO:0048019 receptor antagonist activity(GO:0048019)
0.2 2.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 1.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 2.4 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.2 2.9 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.2 1.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 20.5 GO:0060090 binding, bridging(GO:0060090)
0.2 4.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.2 5.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 4.5 GO:0016208 AMP binding(GO:0016208)
0.2 12.3 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.2 1.6 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 12.4 GO:0003777 microtubule motor activity(GO:0003777)
0.1 3.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 2.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 2.7 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.9 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 2.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 5.8 GO:0008013 beta-catenin binding(GO:0008013)
0.1 25.9 GO:0008017 microtubule binding(GO:0008017)
0.1 21.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 6.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 9.6 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 9.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 3.0 GO:0031072 heat shock protein binding(GO:0031072)
0.1 16.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 2.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 3.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 4.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 1.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 20.4 GO:0008237 metallopeptidase activity(GO:0008237)
0.1 1.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 9.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 7.5 GO:0045296 cadherin binding(GO:0045296)
0.1 2.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 12.2 GO:0005179 hormone activity(GO:0005179)
0.1 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 3.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 2.2 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 2.5 GO:0004707 MAP kinase activity(GO:0004707)
0.1 1.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 2.8 GO:0016247 channel regulator activity(GO:0016247)
0.1 21.7 GO:0005096 GTPase activator activity(GO:0005096)
0.1 0.4 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 3.1 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.2 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 5.4 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.0 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 1.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 6.4 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.7 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 33.5 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 8.2 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 2.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 1.9 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.4 GO:2001069 glycogen binding(GO:2001069)
0.0 15.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.3 GO:0019894 kinesin binding(GO:0019894)
0.0 5.1 GO:0004672 protein kinase activity(GO:0004672)
0.0 0.3 GO:0008320 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 3.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.2 GO:0019904 protein domain specific binding(GO:0019904)
0.0 10.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 2.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 7.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.7 22.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.6 37.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.5 16.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.4 3.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.4 16.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.3 3.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.3 1.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.3 4.7 PID ARF 3PATHWAY Arf1 pathway
0.3 3.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.2 16.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.2 6.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.2 9.2 PID P53 REGULATION PATHWAY p53 pathway
0.2 5.7 ST G ALPHA I PATHWAY G alpha i Pathway
0.2 4.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 2.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 1.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 3.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 1.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 44.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
2.1 10.6 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
1.3 3.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
1.2 20.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.9 8.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.6 9.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.4 14.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.4 10.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.4 15.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.3 4.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 3.7 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 5.2 REACTOME KINESINS Genes involved in Kinesins
0.2 10.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 8.5 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.2 3.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 3.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 5.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.2 0.9 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 1.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 2.9 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 10.6 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 6.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.0 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 2.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 0.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 1.0 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 3.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 3.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 4.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 1.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 2.4 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.7 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 2.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 3.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation