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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for osr1

Z-value: 0.84

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Transcription factors associated with osr1

Gene Symbol Gene ID Gene Info
osr1
ENSDARG00000014091 odd-skipped related transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
osr1dr11_v1_chr13_+_32148338_321483380.602.3e-10Click!

Activity profile of osr1 motif

Sorted Z-values of osr1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_55981288 16.28 ENSDART00000146616
si:dkey-189h5.6
si:dkey-189h5.6
chr3_-_61181018 9.01 ENSDART00000187970
pvalb4
parvalbumin 4
chr14_+_51098036 8.22 ENSDART00000184118
CABZ01078594.1

chr7_+_29955368 7.86 ENSDART00000173686
tpma
alpha-tropomyosin
chr9_-_45601103 7.52 ENSDART00000180465
agr1
anterior gradient 1
chr7_+_29954709 7.43 ENSDART00000173904
tpma
alpha-tropomyosin
chr13_+_30696286 6.38 ENSDART00000192411
cxcl18a.1
chemokine (C-X-C motif) ligand 18a, duplicate 1
chr19_-_25519310 6.16 ENSDART00000089882
C1GALT1 (1 of many)
si:dkey-202e17.1
chr2_+_20539402 6.14 ENSDART00000129585
si:ch73-14h1.2
si:ch73-14h1.2
chr7_+_22767678 6.04 ENSDART00000137203
ponzr6
plac8 onzin related protein 6
chr1_-_59130695 6.00 ENSDART00000152560
FP015850.1

chr11_-_33960318 5.96 ENSDART00000087597
col6a2
collagen, type VI, alpha 2
chr7_-_71758613 5.67 ENSDART00000166724
myom1b
myomesin 1b
chr16_-_31469065 5.39 ENSDART00000182397
si:ch211-251p5.5
si:ch211-251p5.5
chr18_+_7204378 5.13 ENSDART00000142905
vwf
von Willebrand factor
chr7_+_31871830 5.09 ENSDART00000139899
mybpc3
myosin binding protein C, cardiac
chr19_-_25519612 5.01 ENSDART00000133150
C1GALT1 (1 of many)
si:dkey-202e17.1
chr21_+_4702773 5.01 ENSDART00000147404
si:dkey-102g19.3
si:dkey-102g19.3
chr3_-_16784280 4.98 ENSDART00000137108
ENSDART00000137276
si:dkey-30j10.5
si:dkey-30j10.5
chr21_+_33454147 4.97 ENSDART00000053208
rps14
ribosomal protein S14
chr21_+_45627775 4.83 ENSDART00000185466
irf1b
interferon regulatory factor 1b
chr14_+_29769336 4.76 ENSDART00000105898
si:dkey-34l15.1
si:dkey-34l15.1
chr5_+_13373593 4.75 ENSDART00000051668
ENSDART00000183883
ccl19a.2
chemokine (C-C motif) ligand 19a, tandem duplicate 2
chr3_-_32958505 4.74 ENSDART00000147374
ENSDART00000136919
casp6l1
caspase 6, apoptosis-related cysteine peptidase, like 1
chr15_-_12011202 4.56 ENSDART00000160427
ENSDART00000168715
si:dkey-202l22.6
si:dkey-202l22.6
chr25_+_37435720 4.56 ENSDART00000164390
chmp1a
charged multivesicular body protein 1A
chr19_+_31576849 4.44 ENSDART00000134107
ENSDART00000088401
acot13
acyl-CoA thioesterase 13
chr5_+_29831235 4.35 ENSDART00000109660
f11r.1
F11 receptor, tandem duplicate 1
chr3_+_23063718 4.31 ENSDART00000140225
ENSDART00000184431
b4galnt2.1
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 1
chr18_-_49116382 4.31 ENSDART00000174157
BX663503.3

chr11_+_31285127 4.29 ENSDART00000160154
si:dkey-238i5.2
si:dkey-238i5.2
chr3_-_29899172 4.11 ENSDART00000140518
ENSDART00000020311
rpl27
ribosomal protein L27
chr6_+_54576520 4.01 ENSDART00000093199
ENSDART00000127519
ENSDART00000157142
tead3b
TEA domain family member 3 b
chr17_-_45378473 3.99 ENSDART00000132969
znf106a
zinc finger protein 106a
chr10_+_38512270 3.98 ENSDART00000109752
serpinh1a
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a
chr18_+_30847237 3.95 ENSDART00000012374
foxf1
forkhead box F1
chr14_+_4151379 3.94 ENSDART00000160431
dhrs13l1
dehydrogenase/reductase (SDR family) member 13 like 1
chr8_-_2506327 3.88 ENSDART00000101125
ENSDART00000125124
rpl6
ribosomal protein L6
chr16_-_46660680 3.86 ENSDART00000159209
ENSDART00000191929
tmem176l.4
transmembrane protein 176l.4
chr24_+_19518303 3.80 ENSDART00000027022
ENSDART00000056080
sulf1
sulfatase 1
chr5_-_30978381 3.79 ENSDART00000127787
spns3
spinster homolog 3 (Drosophila)
chr19_-_35361556 3.77 ENSDART00000012167
ndufs5
NADH dehydrogenase (ubiquinone) Fe-S protein 5
chr8_+_4798158 3.75 ENSDART00000031650
hsp70l
heat shock cognate 70-kd protein, like
chr20_+_16881883 3.65 ENSDART00000130107
nfkbiaa
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr7_-_8315179 3.62 ENSDART00000184049
f13a1b
coagulation factor XIII, A1 polypeptide b
chr1_+_54650048 3.60 ENSDART00000141207
si:ch211-202h22.7
si:ch211-202h22.7
chr5_+_25317061 3.57 ENSDART00000170097
trpm6
transient receptor potential cation channel, subfamily M, member 6
chr19_-_5769553 3.54 ENSDART00000175003
si:ch211-264f5.6
si:ch211-264f5.6
chr23_-_42752387 3.51 ENSDART00000149781
si:ch73-217n20.1
si:ch73-217n20.1
chr21_-_25295087 3.46 ENSDART00000087910
ENSDART00000147860
st14b
suppression of tumorigenicity 14 (colon carcinoma) b
chr23_-_42752550 3.33 ENSDART00000187059
si:ch73-217n20.1
si:ch73-217n20.1
chr21_-_7940043 3.30 ENSDART00000099733
ENSDART00000136671
f2rl1.1
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1
chr6_+_52947186 3.30 ENSDART00000155831
uba7
ubiquitin-like modifier activating enzyme 7
chr15_-_35960250 3.27 ENSDART00000186765
col4a4
collagen, type IV, alpha 4
chr13_+_25397098 3.21 ENSDART00000132953
gsto2
glutathione S-transferase omega 2
chr15_+_404891 3.20 ENSDART00000155682
nipsnap2
nipsnap homolog 2
chr13_+_25396896 3.20 ENSDART00000041257
gsto2
glutathione S-transferase omega 2
chr13_+_12456412 3.08 ENSDART00000057762
dapp1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr22_+_29991834 2.98 ENSDART00000147728
si:dkey-286j15.3
si:dkey-286j15.3
chr9_-_33063083 2.88 ENSDART00000048550
si:ch211-125e6.5
si:ch211-125e6.5
chr5_-_56513825 2.79 ENSDART00000024207
tbx2a
T-box 2a
chr11_+_21053488 2.79 ENSDART00000189860
zgc:113307
zgc:113307
chr7_-_17600415 2.76 ENSDART00000080717
nitr6b
novel immune-type receptor 6b
chr16_-_28876479 2.74 ENSDART00000047862
si:dkey-239n17.4
si:dkey-239n17.4
chr3_-_4303262 2.67 ENSDART00000112819
si:dkey-73p2.2
si:dkey-73p2.2
chr2_+_36114194 2.65 ENSDART00000113547
traj39
T-cell receptor alpha joining 39
chr23_-_9925568 2.64 ENSDART00000081268
si:ch211-220i18.4
si:ch211-220i18.4
chr9_-_5263947 2.63 ENSDART00000088342
cytip
cytohesin 1 interacting protein
chr8_+_21297217 2.51 ENSDART00000142836
itpr3
inositol 1,4,5-trisphosphate receptor, type 3
chr3_+_32571929 2.49 ENSDART00000151025
si:ch73-248e21.1
si:ch73-248e21.1
chr3_-_10751491 2.48 ENSDART00000016351
zgc:112965
zgc:112965
chr2_-_37896646 2.47 ENSDART00000075931
hbl1
hexose-binding lectin 1
chr23_+_43809484 2.44 ENSDART00000149534
si:ch211-149b19.3
si:ch211-149b19.3
chr21_-_11657043 2.43 ENSDART00000141297
cast
calpastatin
chr22_+_661711 2.41 ENSDART00000113795
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr20_+_53522059 2.41 ENSDART00000147570
pak6b
p21 protein (Cdc42/Rac)-activated kinase 6b
chr21_-_32036597 2.40 ENSDART00000114964
zgc:165573
zgc:165573
chr2_-_15318786 2.40 ENSDART00000135851
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr15_-_39848822 2.40 ENSDART00000155230
si:dkey-263j23.1
si:dkey-263j23.1
chr20_-_26866111 2.38 ENSDART00000077767
mylk4b
myosin light chain kinase family, member 4b
chr6_+_52947699 2.33 ENSDART00000180913
uba7
ubiquitin-like modifier activating enzyme 7
chr6_-_8407406 2.31 ENSDART00000151355
ptger1a
prostaglandin E receptor 1a (subtype EP1)
chr7_-_17635717 2.29 ENSDART00000080704
nitr6b
novel immune-type receptor 6b
chr18_-_46258612 2.22 ENSDART00000153930
si:dkey-244a7.1
si:dkey-244a7.1
chr14_-_26536504 2.21 ENSDART00000105933
tgfbi
transforming growth factor, beta-induced
chr3_+_32129632 2.14 ENSDART00000174522
zgc:109934
zgc:109934
chr12_-_38548299 2.12 ENSDART00000153374
si:dkey-1f1.3
si:dkey-1f1.3
chr14_+_21905492 2.11 ENSDART00000054437
tbc1d10c
TBC1 domain family, member 10C
chr11_+_2198831 2.10 ENSDART00000160515
hoxc6b
homeobox C6b
chr4_+_10616626 2.10 ENSDART00000067251
ENSDART00000143690
cped1
cadherin-like and PC-esterase domain containing 1
chr23_-_26652273 2.10 ENSDART00000112124
ENSDART00000111029
hspg2
heparan sulfate proteoglycan 2
chr18_-_977075 2.08 ENSDART00000032392
dhdhl
dihydrodiol dehydrogenase (dimeric), like
chr3_+_6291635 2.08 ENSDART00000185055
ENSDART00000157707
si:ch211-12p12.2
si:ch211-12p12.2
chr18_-_45736 2.06 ENSDART00000148373
ENSDART00000148950
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr8_-_36469117 2.05 ENSDART00000111240
mhc2dab
major histocompatibility complex class II DAB gene
chr3_-_15144067 2.03 ENSDART00000127738
ENSDART00000060426
ENSDART00000180799
fam173a
family with sequence similarity 173, member A
chr4_+_8569199 2.00 ENSDART00000165181
wnt5b
wingless-type MMTV integration site family, member 5b
chr1_+_55643198 2.00 ENSDART00000060693
adgre7
adhesion G protein-coupled receptor E7
chr10_+_29840725 2.00 ENSDART00000127268
BX120005.1

chr2_-_37896965 1.95 ENSDART00000129852
hbl1
hexose-binding lectin 1
chr20_-_29418620 1.93 ENSDART00000172634
ryr3
ryanodine receptor 3
chr20_-_29787192 1.89 ENSDART00000125348
ENSDART00000048759
id2b
inhibitor of DNA binding 2b
chr1_-_58064738 1.89 ENSDART00000073778
caspb
caspase b
chr6_+_19950107 1.86 ENSDART00000181632
pik3r5
phosphoinositide-3-kinase, regulatory subunit 5
chr23_-_30041065 1.86 ENSDART00000131209
ENSDART00000127192
ccdc187
coiled-coil domain containing 187
chr3_-_48980319 1.84 ENSDART00000165319
ftr42
finTRIM family, member 42
chr3_-_2072630 1.82 ENSDART00000189404
BX005442.3

chr6_-_48087152 1.79 ENSDART00000180614
slc2a1b
solute carrier family 2 (facilitated glucose transporter), member 1b
chr25_+_26798673 1.76 ENSDART00000157235
ca12
carbonic anhydrase XII
chr20_+_53521648 1.76 ENSDART00000139794
pak6b
p21 protein (Cdc42/Rac)-activated kinase 6b
chr4_-_3805992 1.76 ENSDART00000190125
si:dkey-61f9.1
si:dkey-61f9.1
chr13_-_45523026 1.75 ENSDART00000020663
rhd
Rh blood group, D antigen
chr2_-_4868002 1.75 ENSDART00000189835
tfr1a
transferrin receptor 1a
chr21_-_40834413 1.72 ENSDART00000148513
limk1b
LIM domain kinase 1b
chr11_-_40457325 1.71 ENSDART00000128442
tnfrsf1b
tumor necrosis factor receptor superfamily, member 1B
chr9_+_33423170 1.70 ENSDART00000141542
si:dkey-216e24.9
si:dkey-216e24.9
chr17_-_50018133 1.69 ENSDART00000112267
filip1a
filamin A interacting protein 1a
chr16_+_35344031 1.66 ENSDART00000167140
si:dkey-34d22.1
si:dkey-34d22.1
chr17_-_6198823 1.63 ENSDART00000028407
ENSDART00000193636
ptk2ba
protein tyrosine kinase 2 beta, a
chr16_-_21810668 1.63 ENSDART00000156575
dicp3.3
diverse immunoglobulin domain-containing protein 3.3
chr21_-_26490186 1.62 ENSDART00000009889
zgc:110540
zgc:110540
chr20_+_43113465 1.60 ENSDART00000004842
dusp23a
dual specificity phosphatase 23a
chr10_-_45058886 1.59 ENSDART00000159347
mrps24
mitochondrial ribosomal protein S24
chr1_+_40199074 1.59 ENSDART00000179679
ENSDART00000136849
si:ch211-113e8.5
si:ch211-113e8.5
chr14_-_1538600 1.58 ENSDART00000180925
CABZ01109480.1

chr6_-_11812224 1.58 ENSDART00000150989
march7
membrane-associated ring finger (C3HC4) 7
chr23_+_4709607 1.57 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
raf1a
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr7_+_17374560 1.56 ENSDART00000172272
ENSDART00000073467
nitr7a
novel immune-type receptor 7a
chr4_-_1824836 1.56 ENSDART00000111858
mrpl42
mitochondrial ribosomal protein L42
chr1_+_230363 1.55 ENSDART00000153285
tfdp1b
transcription factor Dp-1, b
chr25_+_35212919 1.52 ENSDART00000180127
ano5a
anoctamin 5a
chr5_-_16472719 1.52 ENSDART00000162071
piwil2
piwi-like RNA-mediated gene silencing 2
chr22_-_5006801 1.52 ENSDART00000106166
rx1
retinal homeobox gene 1
chr7_+_20656942 1.51 ENSDART00000100898
tnfsf12
TNF superfamily member 12
chr22_+_19473804 1.51 ENSDART00000135085
ENSDART00000147673
ENSDART00000156818
si:dkey-78l4.7
si:dkey-78l4.7
chr21_-_25250594 1.47 ENSDART00000163862
nfrkb
nuclear factor related to kappaB binding protein
chr3_-_26115558 1.46 ENSDART00000078671
ENSDART00000124762
hsp70.1
heat shock cognate 70-kd protein, tandem duplicate 1
chr14_+_5383060 1.46 ENSDART00000187825
lbx2
ladybird homeobox 2
chr25_-_31433512 1.46 ENSDART00000067028
zgc:172145
zgc:172145
chr1_-_34750169 1.46 ENSDART00000149380
si:dkey-151m22.8
si:dkey-151m22.8
chr8_-_20245892 1.42 ENSDART00000136911
acer1
alkaline ceramidase 1
chr6_+_49082796 1.42 ENSDART00000182446
tshba
thyroid stimulating hormone, beta subunit, a
chr5_-_5831037 1.42 ENSDART00000112856
zmp:0000000846
zmp:0000000846
chr13_+_40686133 1.41 ENSDART00000146112
hps1
Hermansky-Pudlak syndrome 1
chr20_-_36575475 1.39 ENSDART00000062893
enah
enabled homolog (Drosophila)
chr4_+_64034834 1.39 ENSDART00000160654
si:dkey-179k24.5
si:dkey-179k24.5
chr24_+_10413484 1.39 ENSDART00000111014
myca
MYC proto-oncogene, bHLH transcription factor a
chr12_-_7824291 1.35 ENSDART00000148673
ENSDART00000149453
ank3b
ankyrin 3b
chr4_+_69262318 1.35 ENSDART00000188841
si:ch211-209j12.6
si:ch211-209j12.6
chr1_-_8140763 1.35 ENSDART00000091508
FAM83G
si:dkeyp-9d4.4
chr7_-_27033080 1.32 ENSDART00000173516
nucb2a
nucleobindin 2a
chr7_-_18508815 1.29 ENSDART00000173539
rgs12a
regulator of G protein signaling 12a
chr8_-_25728628 1.29 ENSDART00000127237
foxp3a
forkhead box P3a
chr3_-_26183699 1.28 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
si:ch211-11k18.4
chr9_-_33121535 1.27 ENSDART00000166371
ENSDART00000138052
zgc:172014
zgc:172014
chr15_-_31357634 1.26 ENSDART00000127485
or111-2
odorant receptor, family D, subfamily 111, member 2
chr5_-_16274058 1.25 ENSDART00000090684
kremen1
kringle containing transmembrane protein 1
chr16_-_26537103 1.25 ENSDART00000134908
ENSDART00000008152
sgk2b
serum/glucocorticoid regulated kinase 2b
chr4_-_67969695 1.25 ENSDART00000190016
si:ch211-223k15.1
si:ch211-223k15.1
chr15_-_952891 1.24 ENSDART00000153780
alox5b.1
arachidonate 5-lipoxygenase b, tandem duplicate 1
chr17_-_23631400 1.22 ENSDART00000079563
fas
Fas cell surface death receptor
chr23_+_4324625 1.21 ENSDART00000146302
ENSDART00000136792
ENSDART00000135027
ENSDART00000179819
sgk2a
serum/glucocorticoid regulated kinase 2a
chr16_+_20871021 1.21 ENSDART00000006429
hibadhb
3-hydroxyisobutyrate dehydrogenase b
chr9_-_34269066 1.19 ENSDART00000059955
ildr1b
immunoglobulin-like domain containing receptor 1b
chr3_-_32973511 1.19 ENSDART00000131808
ENSDART00000103182
casp6l2
caspase 6, apoptosis-related cysteine peptidase, like 2
chr18_+_20869923 1.18 ENSDART00000138471
pgpep1l
pyroglutamyl-peptidase I-like
chr3_-_57765169 1.15 ENSDART00000013376
cant1a
calcium activated nucleotidase 1a
chr6_-_52566574 1.14 ENSDART00000098421
uqcc1
ubiquinol-cytochrome c reductase complex assembly factor 1
chr17_+_32622933 1.11 ENSDART00000077418
ctsba
cathepsin Ba
chr2_-_36918709 1.10 ENSDART00000084876
zgc:153654
zgc:153654
chr23_+_25232711 1.10 ENSDART00000128510
erbb3b
erb-b2 receptor tyrosine kinase 3b
chr15_-_5016039 1.08 ENSDART00000156458
defbl3
defensin, beta-like 3
chr12_-_29305533 1.07 ENSDART00000189410
sh2d4bb
SH2 domain containing 4Bb
chr20_-_5291012 1.07 ENSDART00000122892
cyp46a1.3
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr16_+_46684855 1.06 ENSDART00000058325
lamtor2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr8_+_3496204 1.04 ENSDART00000085993
pxnb
paxillin b
chr24_-_4768955 1.04 ENSDART00000066834
agtr1b
angiotensin II receptor, type 1b
chr17_-_45104750 1.03 ENSDART00000075520
aldh6a1
aldehyde dehydrogenase 6 family, member A1
chr5_-_48307804 1.00 ENSDART00000182831
ENSDART00000186920
ENSDART00000183585
mef2cb
myocyte enhancer factor 2cb
chr3_+_41558682 0.99 ENSDART00000157023
card11
caspase recruitment domain family, member 11
chr8_-_1219815 0.98 ENSDART00000016800
ENSDART00000149969
znf367
zinc finger protein 367
chr4_-_30269748 0.95 ENSDART00000163550
si:dkey-233e3.3
si:dkey-233e3.3
chr2_+_38892631 0.93 ENSDART00000134040
si:ch211-119o8.4
si:ch211-119o8.4
chr8_+_48858132 0.93 ENSDART00000124737
ENSDART00000079644
tp73
tumor protein p73
chr2_+_39021282 0.91 ENSDART00000056577
RBP1 (1 of many)
si:ch211-119o8.7
chr13_+_28417297 0.91 ENSDART00000043658
slc2a15a
solute carrier family 2 (facilitated glucose transporter), member 15a
chr1_-_21723329 0.91 ENSDART00000137138
si:ch211-134c9.2
si:ch211-134c9.2
chr7_+_24729558 0.88 ENSDART00000111542
ENSDART00000170100
shroom4
shroom family member 4
chr1_+_26605065 0.87 ENSDART00000011645
coro2a
coronin, actin binding protein, 2A
chr22_+_22417751 0.84 ENSDART00000105600
ddx59
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr13_-_32635859 0.84 ENSDART00000146249
ENSDART00000145395
ENSDART00000148040
ENSDART00000100650
matn3b
matrilin 3b
chr15_+_22390076 0.84 ENSDART00000183764
oafa
OAF homolog a (Drosophila)
chr4_-_6567355 0.84 ENSDART00000134820
ENSDART00000142087
foxp2
forkhead box P2
chr10_-_34089779 0.83 ENSDART00000140070
pimr144
Pim proto-oncogene, serine/threonine kinase, related 144
chr20_-_9674877 0.82 ENSDART00000134097
nid2b
nidogen 2b (osteonidogen)
chr7_+_4648398 0.81 ENSDART00000148099
si:dkey-83f18.3
si:dkey-83f18.3
chr21_+_13785975 0.81 ENSDART00000134682
slc31a2
solute carrier family 31 (copper transporter), member 2
chr5_+_6617401 0.81 ENSDART00000060532
zgc:110796
zgc:110796
chr16_+_54674556 0.80 ENSDART00000167040
pop1
POP1 homolog, ribonuclease P/MRP subunit
chr11_-_13618412 0.80 ENSDART00000137289
sid1
secreted immunoglobulin domain 1

Network of associatons between targets according to the STRING database.

First level regulatory network of osr1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
1.1 4.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
1.0 5.1 GO:0003210 cardiac atrium formation(GO:0003210)
0.9 2.8 GO:0072068 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.7 3.5 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.5 3.8 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.5 3.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.5 1.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.4 1.7 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.4 4.8 GO:0050688 regulation of defense response to virus(GO:0050688)
0.4 1.5 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.4 2.2 GO:0006574 valine catabolic process(GO:0006574)
0.4 4.4 GO:0050892 intestinal absorption(GO:0050892)
0.4 1.4 GO:1903232 melanosome assembly(GO:1903232)
0.4 4.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.3 2.4 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.3 1.2 GO:0070227 lymphocyte apoptotic process(GO:0070227)
0.3 1.1 GO:0048940 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.3 5.2 GO:0046686 response to cadmium ion(GO:0046686)
0.3 0.8 GO:0007414 axonal defasciculation(GO:0007414)
0.3 1.3 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.2 3.6 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 1.7 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 5.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 1.5 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 3.9 GO:0042574 retinal metabolic process(GO:0042574)
0.2 1.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.2 0.7 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.2 7.2 GO:0030199 collagen fibril organization(GO:0030199)
0.2 0.7 GO:0014909 smooth muscle cell migration(GO:0014909)
0.2 3.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 0.8 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.2 3.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 1.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 1.6 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.1 0.5 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.1 0.5 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 1.3 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 1.4 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 13.0 GO:0061515 myeloid cell development(GO:0061515)
0.1 2.4 GO:0070672 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.1 0.8 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.1 4.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.8 GO:0098773 skin epidermis development(GO:0098773)
0.1 1.7 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1 1.9 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.1 1.2 GO:0043651 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 4.0 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 0.7 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 4.8 GO:0051262 protein tetramerization(GO:0051262)
0.1 1.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 3.0 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 1.7 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 0.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.7 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 1.2 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 2.4 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 7.1 GO:0031101 fin regeneration(GO:0031101)
0.1 2.5 GO:2001236 regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.1 7.1 GO:0048747 muscle fiber development(GO:0048747)
0.1 0.2 GO:0016038 absorption of visible light(GO:0016038)
0.1 0.8 GO:0045471 response to ethanol(GO:0045471)
0.1 2.1 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 1.6 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.1 0.7 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.6 GO:0032543 mitochondrial translation(GO:0032543)
0.0 2.5 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 1.7 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 3.1 GO:0043542 endothelial cell migration(GO:0043542)
0.0 0.4 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.4 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 1.9 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 3.8 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 0.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.7 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 5.7 GO:0006954 inflammatory response(GO:0006954)
0.0 3.5 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 1.0 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.1 GO:0042543 protein N-linked glycosylation via arginine(GO:0042543)
0.0 0.6 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 4.8 GO:0006936 muscle contraction(GO:0006936)
0.0 5.9 GO:0031589 cell-substrate adhesion(GO:0031589)
0.0 0.7 GO:0015671 oxygen transport(GO:0015671)
0.0 8.0 GO:0009617 response to bacterium(GO:0009617)
0.0 0.8 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 1.9 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 1.0 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 1.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.4 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 1.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.4 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.6 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 1.4 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:0006415 translational termination(GO:0006415)
0.0 0.7 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.3 GO:0003323 type B pancreatic cell development(GO:0003323)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.5 1.9 GO:0061702 inflammasome complex(GO:0061702)
0.4 1.4 GO:0031085 BLOC-3 complex(GO:0031085)
0.3 3.8 GO:0008180 COP9 signalosome(GO:0008180)
0.3 4.6 GO:0000815 ESCRT III complex(GO:0000815)
0.3 1.5 GO:1990923 PET complex(GO:1990923)
0.3 1.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.3 5.7 GO:0031430 M band(GO:0031430)
0.3 2.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.8 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.2 1.1 GO:0071986 Ragulator complex(GO:0071986)
0.1 1.9 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 14.7 GO:0005884 actin filament(GO:0005884)
0.1 2.5 GO:0030667 secretory granule membrane(GO:0030667)
0.1 5.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.8 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.1 0.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.6 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 6.2 GO:0005604 basement membrane(GO:0005604)
0.1 3.9 GO:0022626 cytosolic large ribosomal subunit(GO:0022625) cytosolic ribosome(GO:0022626)
0.1 4.7 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 0.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 5.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 4.2 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 3.8 GO:0005795 Golgi stack(GO:0005795)
0.0 1.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.7 GO:0005921 gap junction(GO:0005921)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 3.7 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 1.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 7.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.8 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.7 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 0.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 6.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 11.3 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
0.8 5.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.7 5.0 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.5 5.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 1.7 GO:0004998 transferrin receptor activity(GO:0004998)
0.4 3.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.4 1.2 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.4 1.9 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.4 2.3 GO:0004960 thromboxane receptor activity(GO:0004960)
0.3 2.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.3 1.2 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.3 0.8 GO:0030251 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.3 1.0 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.3 2.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 1.8 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.3 3.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 1.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.2 1.4 GO:0017040 ceramidase activity(GO:0017040)
0.2 1.6 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.2 3.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.1 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.2 2.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 1.5 GO:0034584 piRNA binding(GO:0034584)
0.2 4.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.2 2.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 3.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 1.1 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.2 1.2 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.2 11.1 GO:0008009 chemokine activity(GO:0008009)
0.2 6.2 GO:0005518 collagen binding(GO:0005518)
0.2 0.8 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.2 1.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 1.4 GO:0005522 profilin binding(GO:0005522)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.5 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.3 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.1 0.8 GO:0070728 leucine binding(GO:0070728)
0.1 1.9 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 15.3 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 2.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 1.5 GO:0002020 protease binding(GO:0002020)
0.1 1.0 GO:0050700 CARD domain binding(GO:0050700)
0.1 4.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 1.5 GO:0048018 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.1 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 4.0 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.6 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 1.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.7 GO:0051117 ATPase binding(GO:0051117)
0.1 1.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.7 GO:0031720 haptoglobin binding(GO:0031720)
0.0 9.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 2.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.7 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.5 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 1.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 4.9 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.1 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.7 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 3.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 4.5 GO:0019900 kinase binding(GO:0019900)
0.0 2.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.0 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 1.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 1.5 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 11.2 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.7 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.2 NABA COLLAGENS Genes encoding collagen proteins
0.2 1.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 7.5 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.2 2.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 1.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 4.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 5.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 3.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.3 PID P73PATHWAY p73 transcription factor network
0.0 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.5 6.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 2.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 9.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 2.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 5.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 1.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 13.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 2.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 4.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 0.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 1.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)