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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for patz1

Z-value: 1.93

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Transcription factors associated with patz1

Gene Symbol Gene ID Gene Info
patz1
ENSDARG00000076584 POZ/BTB and AT hook containing zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
patz1dr11_v1_chr6_+_40951227_409512270.232.7e-02Click!

Activity profile of patz1 motif

Sorted Z-values of patz1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_5254699 46.46 ENSDART00000081951
stx1b
syntaxin 1B
chr19_+_48111285 41.36 ENSDART00000169420
nme2b.2
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2
chr2_-_44282796 29.19 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
mpz
myelin protein zero
chr25_-_13363286 29.10 ENSDART00000163735
ENSDART00000169119
ndrg4
NDRG family member 4
chr21_+_26697536 28.03 ENSDART00000004109
gng3
guanine nucleotide binding protein (G protein), gamma 3
chr1_-_14233815 26.89 ENSDART00000044896
camk2d2
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr21_+_13861589 25.18 ENSDART00000015629
ENSDART00000171306
stxbp1a
syntaxin binding protein 1a
chr14_+_33458294 24.72 ENSDART00000075278
atp1b4
ATPase Na+/K+ transporting subunit beta 4
chr14_-_33454595 24.60 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
tmem255a
transmembrane protein 255A
chr1_-_12278522 24.08 ENSDART00000142122
ENSDART00000003825
cplx2l
complexin 2, like
chr9_-_44295071 22.04 ENSDART00000011837
neurod1
neuronal differentiation 1
chr2_+_26179096 20.95 ENSDART00000024662
plppr3a
phospholipid phosphatase related 3a
chr7_+_73630751 20.29 ENSDART00000159745
PCP4L1
si:dkey-46i9.1
chr2_+_59015878 20.21 ENSDART00000148816
ENSDART00000122795
si:ch1073-391i24.1
si:ch1073-391i24.1
chr1_-_38709551 19.07 ENSDART00000128794
gpm6ab
glycoprotein M6Ab
chr19_+_5072918 18.76 ENSDART00000037126
eno2
enolase 2
chr13_+_23214100 18.02 ENSDART00000163393
sorbs1
sorbin and SH3 domain containing 1
chr25_+_21324588 18.01 ENSDART00000151842
lrrn3a
leucine rich repeat neuronal 3a
chr8_-_14052349 17.35 ENSDART00000135811
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr20_+_20672163 17.33 ENSDART00000027758
rtn1b
reticulon 1b
chr2_+_58221163 17.15 ENSDART00000157939
FO704813.1

chr5_-_31901468 17.08 ENSDART00000147814
ENSDART00000141446
coro1cb
coronin, actin binding protein, 1Cb
chr3_-_62380146 17.06 ENSDART00000155853
gprc5ba
G protein-coupled receptor, class C, group 5, member Ba
chr23_+_6232895 16.84 ENSDART00000139795
syt2a
synaptotagmin IIa
chr5_+_36614196 16.74 ENSDART00000150574
nova1
neuro-oncological ventral antigen 1
chr16_-_42390441 16.35 ENSDART00000148475
cspg5a
chondroitin sulfate proteoglycan 5a
chr22_-_20309283 15.44 ENSDART00000182125
ENSDART00000048775
si:dkey-110c1.10
si:dkey-110c1.10
chr11_+_25112269 15.16 ENSDART00000147546
ndrg3a
ndrg family member 3a
chr1_-_10647307 14.30 ENSDART00000103548
si:dkey-31e10.1
si:dkey-31e10.1
chr6_+_38381957 14.28 ENSDART00000087300
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr17_-_36936856 14.14 ENSDART00000010274
ENSDART00000188887
dpysl5a
dihydropyrimidinase-like 5a
chr9_+_29585943 14.06 ENSDART00000185989
ENSDART00000115290
mcf2lb
mcf.2 cell line derived transforming sequence-like b
chr5_-_36837846 14.05 ENSDART00000032481
ckma
creatine kinase, muscle a
chr7_-_58098814 13.97 ENSDART00000147287
ENSDART00000043984
ank2b
ankyrin 2b, neuronal
chr21_+_7823146 13.75 ENSDART00000030579
crhbp
corticotropin releasing hormone binding protein
chr22_+_12366516 13.72 ENSDART00000157802
r3hdm1
R3H domain containing 1
chr9_-_24413008 13.69 ENSDART00000135897
tmeff2a
transmembrane protein with EGF-like and two follistatin-like domains 2a
chr9_-_54840124 13.66 ENSDART00000137214
ENSDART00000085693
gpm6bb
glycoprotein M6Bb
chr2_-_30693742 13.66 ENSDART00000090292
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr20_-_40319890 13.64 ENSDART00000075112
clvs2
clavesin 2
chr6_+_55032439 13.60 ENSDART00000164232
ENSDART00000158845
ENSDART00000157584
ENSDART00000026359
ENSDART00000122794
ENSDART00000183742
mybphb
myosin binding protein Hb
chr1_-_10647484 13.30 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
si:dkey-31e10.1
chr7_+_568819 13.26 ENSDART00000173716
nrxn2b
neurexin 2b
chr13_+_12045758 13.17 ENSDART00000079398
ENSDART00000165467
ENSDART00000165880
gng2
guanine nucleotide binding protein (G protein), gamma 2
chr16_-_42390640 13.01 ENSDART00000193214
ENSDART00000102305
cspg5a
chondroitin sulfate proteoglycan 5a
chr10_-_26179805 12.92 ENSDART00000174797
trim3b
tripartite motif containing 3b
chr7_+_529522 12.90 ENSDART00000190811
nrxn2b
neurexin 2b
chr6_-_42418225 12.49 ENSDART00000002501
ip6k2a
inositol hexakisphosphate kinase 2a
chr25_+_19954576 12.28 ENSDART00000149335
kcna1a
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr17_-_20711735 12.19 ENSDART00000150056
ank3b
ankyrin 3b
chr15_+_1397811 11.48 ENSDART00000102125
schip1
schwannomin interacting protein 1
chr7_-_18168493 11.21 ENSDART00000127428
peli3
pellino E3 ubiquitin protein ligase family member 3
chr5_-_40510397 11.20 ENSDART00000146237
ENSDART00000051065
fsta
follistatin a
chr1_-_26782573 11.19 ENSDART00000090611
sh3gl2a
SH3 domain containing GRB2 like 2a, endophilin A1
chr3_+_54168007 11.19 ENSDART00000109894
olfm2a
olfactomedin 2a
chr24_-_20599781 10.99 ENSDART00000179664
ENSDART00000141823
zbtb47b
zinc finger and BTB domain containing 47b
chr22_-_600016 10.89 ENSDART00000086434
tmcc2
transmembrane and coiled-coil domain family 2
chr17_-_46457622 10.85 ENSDART00000130215
TMEM179 (1 of many)
transmembrane protein 179
chr13_+_22480496 10.62 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
ldb3a
LIM domain binding 3a
chr11_-_97817 10.59 ENSDART00000092903
elmo2
engulfment and cell motility 2
chr25_-_19090479 10.55 ENSDART00000027465
ENSDART00000177670
cacna2d4b
calcium channel, voltage-dependent, alpha 2/delta subunit 4b
chr25_+_37126921 10.48 ENSDART00000124331
si:ch1073-174d20.1
si:ch1073-174d20.1
chr13_+_36633355 10.38 ENSDART00000135612
si:ch211-67f24.7
si:ch211-67f24.7
chr12_-_35505610 10.34 ENSDART00000105518
camk2g1
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr4_+_19534833 10.31 ENSDART00000140028
lrrc4.1
leucine rich repeat containing 4.1
chr12_-_4651988 10.30 ENSDART00000182836
si:ch211-255p10.4
si:ch211-255p10.4
chr2_+_26303627 10.18 ENSDART00000040278
efna2a
ephrin-A2a
chr7_+_48460239 10.13 ENSDART00000052113
lingo1b
leucine rich repeat and Ig domain containing 1b
chr10_+_32561317 10.00 ENSDART00000109029
map6a
microtubule-associated protein 6a
chr3_-_19133003 9.94 ENSDART00000145215
grin2ca
glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca
chr23_-_637347 9.81 ENSDART00000132175
l1camb
L1 cell adhesion molecule, paralog b
chr15_-_12500938 9.68 ENSDART00000159627
scn4ba
sodium channel, voltage-gated, type IV, beta a
chr11_-_103136 9.64 ENSDART00000173308
ENSDART00000162982
elmo2
engulfment and cell motility 2
chr3_+_62126981 9.59 ENSDART00000060527
drc3
dynein regulatory complex subunit 3
chr14_-_18671334 9.58 ENSDART00000182381
slitrk4
SLIT and NTRK-like family, member 4
chr1_+_54908895 9.50 ENSDART00000145652
golga7ba
golgin A7 family, member Ba
chr23_-_45407631 9.48 ENSDART00000148484
ENSDART00000150186
zgc:101853
zgc:101853
chr13_+_23677949 9.42 ENSDART00000144215
pcnxl2
pecanex-like 2 (Drosophila)
chr13_+_4405282 9.34 ENSDART00000148280
prr18
proline rich 18
chr1_-_22834824 9.32 ENSDART00000043556
ldb2b
LIM domain binding 2b
chr25_+_5035343 9.32 ENSDART00000011751
parvb
parvin, beta
chr5_-_38506981 9.31 ENSDART00000097822
atp1b2b
ATPase Na+/K+ transporting subunit beta 2b
chr16_+_31853919 9.14 ENSDART00000133886
atn1
atrophin 1
chr16_+_36768674 9.07 ENSDART00000169208
ENSDART00000180470
si:ch73-215d9.1
si:ch73-215d9.1
chr8_-_19051906 8.96 ENSDART00000089024
sema6bb
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb
chr4_-_789645 8.87 ENSDART00000164441
mapre3b
microtubule-associated protein, RP/EB family, member 3b
chr13_+_22480857 8.81 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
ldb3a
LIM domain binding 3a
chr13_+_38430466 8.69 ENSDART00000132691
adgrb3
adhesion G protein-coupled receptor B3
chr11_+_37137196 8.68 ENSDART00000172950
wnk2
WNK lysine deficient protein kinase 2
chr8_+_11687254 8.44 ENSDART00000042040
atp2a2a
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr16_-_24135508 8.41 ENSDART00000171819
ENSDART00000103176
bcam
basal cell adhesion molecule (Lutheran blood group)
chr6_-_58828398 8.37 ENSDART00000090634
kif5ab
kinesin family member 5A, b
chr3_-_5964557 8.36 ENSDART00000184738
BX284638.1

chr13_+_32740509 8.26 ENSDART00000076423
ENSDART00000160138
sobpa
sine oculis binding protein homolog (Drosophila) a
chr13_+_1100197 8.26 ENSDART00000139560
ppp3r1a
protein phosphatase 3, regulatory subunit B, alpha a
chr25_+_35375848 8.13 ENSDART00000155721
ano3
anoctamin 3
chr10_-_27197044 7.96 ENSDART00000137928
auts2a
autism susceptibility candidate 2a
chr11_-_29833698 7.94 ENSDART00000079149
xk
X-linked Kx blood group (McLeod syndrome)
chr10_+_7182168 7.92 ENSDART00000172766
psd3l
pleckstrin and Sec7 domain containing 3, like
chr21_-_27185915 7.88 ENSDART00000135052
slc8a4a
solute carrier family 8 (sodium/calcium exchanger), member 4a
chr9_+_13714379 7.86 ENSDART00000017593
ENSDART00000145503
tmem237a
transmembrane protein 237a
chr6_+_54142311 7.81 ENSDART00000154115
hmga1b
high mobility group AT-hook 1b
chr6_-_58828113 7.80 ENSDART00000180934
kif5ab
kinesin family member 5A, b
chr6_+_54888493 7.49 ENSDART00000113331
nav1b
neuron navigator 1b
chr5_-_31928913 7.46 ENSDART00000142919
ssh1b
slingshot protein phosphatase 1b
chr7_-_38477235 7.44 ENSDART00000084355
zgc:165481
zgc:165481
chr9_-_27442339 7.38 ENSDART00000138602
stxbp5l
syntaxin binding protein 5-like
chr22_+_465269 7.36 ENSDART00000145767
celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr6_-_35738836 7.23 ENSDART00000111642
brinp3a.1
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr12_+_34732262 7.20 ENSDART00000169634
si:dkey-21c1.8
si:dkey-21c1.8
chr15_-_47956388 7.20 ENSDART00000116506
si:ch1073-111c8.3
si:ch1073-111c8.3
chr9_-_33749556 7.19 ENSDART00000149383
ndp
Norrie disease (pseudoglioma)
chr23_-_35064785 7.08 ENSDART00000172240
BX294434.1

chr5_-_28606916 7.08 ENSDART00000026107
ENSDART00000137717
tnc
tenascin C
chr20_+_18741089 7.08 ENSDART00000183218
fam167ab
family with sequence similarity 167, member Ab
chr14_-_29799993 7.04 ENSDART00000133775
ENSDART00000005568
pdlim3b
PDZ and LIM domain 3b
chr11_+_23933016 7.02 ENSDART00000000486
cntn2
contactin 2
chr1_-_40994259 7.02 ENSDART00000101562
adra2c
adrenoceptor alpha 2C
chr20_+_11800063 6.99 ENSDART00000152230
si:ch211-155o21.4
si:ch211-155o21.4
chr19_+_9533008 6.85 ENSDART00000104607
fam131ba
family with sequence similarity 131, member Ba
chr17_+_1323699 6.84 ENSDART00000172540
adssl1
adenylosuccinate synthase like 1
chr13_+_12045475 6.74 ENSDART00000163053
ENSDART00000160812
ENSDART00000158244
gng2
guanine nucleotide binding protein (G protein), gamma 2
chr18_-_6477662 6.70 ENSDART00000161263
iqsec3b
IQ motif and Sec7 domain 3b
chr21_+_15824182 6.54 ENSDART00000065779
gnrh2
gonadotropin-releasing hormone 2
chr15_-_9421481 6.54 ENSDART00000189045
ENSDART00000177158
sacs
sacsin molecular chaperone
chr16_-_10404383 6.45 ENSDART00000173412
si:ch73-54f23.4
si:ch73-54f23.4
chr10_-_21054059 6.44 ENSDART00000139733
pcdh1a
protocadherin 1a
chr10_+_7182423 6.39 ENSDART00000186788
psd3l
pleckstrin and Sec7 domain containing 3, like
chr19_+_233143 6.36 ENSDART00000175273
syngap1a
synaptic Ras GTPase activating protein 1a
chr17_-_15657029 6.29 ENSDART00000153925
fut9a
fucosyltransferase 9a
chr4_+_19535946 6.25 ENSDART00000192342
ENSDART00000183740
ENSDART00000180812
ENSDART00000180017
lrrc4.1
leucine rich repeat containing 4.1
chr17_+_5623514 6.24 ENSDART00000171220
ENSDART00000176083
CU571310.1

chr8_-_410199 6.22 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
trim36
tripartite motif containing 36
chr25_-_29316193 6.20 ENSDART00000088249
hcn4l
hyperpolarization activated cyclic nucleotide-gated potassium channel 4l
chr12_+_9761685 6.18 ENSDART00000189522
ppp1r9bb
protein phosphatase 1, regulatory subunit 9Bb
chr3_-_37476475 6.04 ENSDART00000148107
si:ch211-278a6.1
si:ch211-278a6.1
chr21_-_37889727 6.02 ENSDART00000163612
ENSDART00000180958
gabrb4
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr23_+_22335407 5.92 ENSDART00000147696
rap1gap
RAP1 GTPase activating protein
chr6_+_58492201 5.91 ENSDART00000156375
kcnq2b
potassium voltage-gated channel, KQT-like subfamily, member 2b
chr23_+_36601984 5.89 ENSDART00000128598
igfbp6b
insulin-like growth factor binding protein 6b
chr8_+_25767610 5.86 ENSDART00000062406
cacna1sb
calcium channel, voltage-dependent, L type, alpha 1S subunit, b
chr1_-_41817742 5.84 ENSDART00000144098
ENSDART00000053681
rnf24
ring finger protein 24
chr15_-_5742531 5.82 ENSDART00000045985
phkg1a
phosphorylase kinase, gamma 1a (muscle)
chr2_-_36818132 5.79 ENSDART00000110447
slitrk3b
SLIT and NTRK-like family, member 3b
chr3_-_52614747 5.78 ENSDART00000154365
trim35-13
tripartite motif containing 35-13
chr9_-_16877456 5.72 ENSDART00000161105
ENSDART00000160869
fbxl3a
F-box and leucine-rich repeat protein 3a
chr8_+_25173317 5.71 ENSDART00000142006
gpr61
G protein-coupled receptor 61
chr2_+_24786765 5.71 ENSDART00000141030
pde4ca
phosphodiesterase 4C, cAMP-specific a
chr3_+_16265924 5.59 ENSDART00000122519
st8sia6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr7_-_6592142 5.59 ENSDART00000160137
kcnj10a
potassium inwardly-rectifying channel, subfamily J, member 10a
chr20_+_19793620 5.57 ENSDART00000136317
chrna2b
cholinergic receptor, nicotinic, alpha 2b (neuronal)
chr20_-_24963038 5.52 ENSDART00000102788
ENSDART00000159122
epha7
eph receptor A7
chr1_+_54677173 5.49 ENSDART00000114705
gprc5bb
G protein-coupled receptor, class C, group 5, member Bb
chr6_+_54358529 5.48 ENSDART00000153704
anks1ab
ankyrin repeat and sterile alpha motif domain containing 1Ab
chr2_+_3595333 5.28 ENSDART00000041052
c1ql3b
complement component 1, q subcomponent-like 3b
chr5_-_31875645 5.25 ENSDART00000098160
tmem119b
transmembrane protein 119b
chr10_+_43188678 5.19 ENSDART00000012522
vcanb
versican b
chr21_+_1143141 5.17 ENSDART00000178294
CABZ01086139.1

chr8_+_8291492 5.14 ENSDART00000151314
srpk3
SRSF protein kinase 3
chr17_+_52822422 5.12 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr7_+_10701770 5.11 ENSDART00000167323
arnt2
aryl-hydrocarbon receptor nuclear translocator 2
chr4_+_13452907 5.05 ENSDART00000186116
dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr9_+_2452672 4.98 ENSDART00000193993
chn1
chimerin 1
chr10_+_1849874 4.91 ENSDART00000158897
ENSDART00000149956
apc
adenomatous polyposis coli
chr8_+_25267903 4.91 ENSDART00000093090
ampd2b
adenosine monophosphate deaminase 2b
chr7_-_5148388 4.81 ENSDART00000143549
si:ch211-272h9.5
si:ch211-272h9.5
chr7_-_32833153 4.80 ENSDART00000099871
ENSDART00000099872
slc17a6b
solute carrier family 17 (vesicular glutamate transporter), member 6b
chr16_+_29043813 4.72 ENSDART00000122681
nes
nestin
chr6_+_13606410 4.65 ENSDART00000104716
asic4b
acid-sensing (proton-gated) ion channel family member 4b
chr4_+_13452437 4.65 ENSDART00000145069
dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr19_-_6873107 4.61 ENSDART00000124440
CABZ01029822.1

chr10_-_1718395 4.57 ENSDART00000137620
si:ch73-46j18.5
si:ch73-46j18.5
chr10_-_43540196 4.54 ENSDART00000170891
si:ch73-215f7.1
si:ch73-215f7.1
chr9_+_3429662 4.54 ENSDART00000160977
ENSDART00000114168
ENSDART00000082153
CU469503.1
itga6a

integrin, alpha 6a
chr16_+_10918252 4.51 ENSDART00000172949
pou2f2a
POU class 2 homeobox 2a
chr18_+_3243292 4.49 ENSDART00000166580
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr13_+_3819475 4.49 ENSDART00000139958
qkib
QKI, KH domain containing, RNA binding b
chr14_+_24283915 4.47 ENSDART00000172868
klhl3
kelch-like family member 3
chr10_+_8629275 4.41 ENSDART00000129643
aplnrb
apelin receptor b
chr10_-_5844915 4.40 ENSDART00000185929
ankrd55
ankyrin repeat domain 55
chr20_+_22681066 4.40 ENSDART00000143286
lnx1
ligand of numb-protein X 1
chr7_-_24236364 4.38 ENSDART00000010124
slc7a8a
solute carrier family 7 (amino acid transporter light chain, L system), member 8a
chr2_-_44183613 4.36 ENSDART00000079596
cadm3
cell adhesion molecule 3
chr2_-_1569250 4.31 ENSDART00000167202
dab1b
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr8_+_1082100 4.29 ENSDART00000149276
lzts3b
leucine zipper, putative tumor suppressor family member 3b
chr11_-_3334248 4.20 ENSDART00000154314
ENSDART00000121861
prph
peripherin
chr14_+_11946395 4.19 ENSDART00000193290
frmpd3
FERM and PDZ domain containing 3
chr23_-_28294763 4.18 ENSDART00000139537
znf385a
zinc finger protein 385A
chr18_-_42333428 4.14 ENSDART00000034225
cntn5
contactin 5
chr4_+_74554605 4.13 ENSDART00000009653
kcna1b
potassium voltage-gated channel, shaker-related subfamily, member 1b
chr6_-_35779348 4.11 ENSDART00000191159
brinp3a.1
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr7_-_18881358 4.09 ENSDART00000021502
mllt3
MLLT3, super elongation complex subunit
chr20_+_25370 4.08 ENSDART00000152518
lrfn2b
leucine rich repeat and fibronectin type III domain containing 2b
chr19_+_22216778 4.03 ENSDART00000052521
nfatc1
nuclear factor of activated T cells 1
chr21_+_28445052 4.03 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr2_+_33052169 4.01 ENSDART00000180008
rnf220a
ring finger protein 220a
chr10_+_33895315 3.89 ENSDART00000142881
fryb
furry homolog b (Drosophila)
chr22_-_26558166 3.80 ENSDART00000111125
glis2a
GLIS family zinc finger 2a
chr1_+_604127 3.78 ENSDART00000133165
jam2a
junctional adhesion molecule 2a
chr14_-_2209742 3.69 ENSDART00000054889
pcdh2ab5
protocadherin 2 alpha b 5

Network of associatons between targets according to the STRING database.

First level regulatory network of patz1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 46.5 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
4.6 13.7 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
4.6 13.7 GO:1903792 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
2.9 29.4 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
2.8 14.0 GO:0036371 protein localization to T-tubule(GO:0036371)
2.4 7.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
2.3 18.8 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
2.3 7.0 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
2.3 16.3 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
2.2 11.2 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
2.1 29.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
1.9 11.5 GO:0035332 positive regulation of hippo signaling(GO:0035332)
1.9 30.4 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
1.8 5.3 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
1.7 8.7 GO:0016322 neuron remodeling(GO:0016322)
1.5 6.0 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.5 4.5 GO:0072156 distal tubule morphogenesis(GO:0072156)
1.4 7.0 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
1.3 4.0 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
1.2 5.0 GO:0021557 oculomotor nerve development(GO:0021557)
1.2 20.7 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
1.2 4.7 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
1.1 11.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
1.1 4.4 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
1.1 14.0 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
1.0 7.2 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
1.0 11.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
1.0 8.9 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.9 12.5 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.9 3.5 GO:0042481 regulation of odontogenesis(GO:0042481)
0.8 12.5 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.8 19.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.8 9.9 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.8 2.5 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.8 0.8 GO:0002791 regulation of peptide secretion(GO:0002791) positive regulation of peptide secretion(GO:0002793) regulation of peptide transport(GO:0090087) regulation of peptide hormone secretion(GO:0090276) positive regulation of peptide hormone secretion(GO:0090277)
0.8 8.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.8 5.6 GO:0036268 swimming(GO:0036268)
0.8 11.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.8 2.3 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.8 16.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.7 4.5 GO:0003232 bulbus arteriosus development(GO:0003232)
0.7 11.8 GO:1903288 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.7 2.8 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.7 5.6 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.7 8.3 GO:0021754 facial nucleus development(GO:0021754)
0.7 10.6 GO:0046549 retinal cone cell development(GO:0046549)
0.7 7.9 GO:0042044 fluid transport(GO:0042044)
0.7 9.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.6 1.9 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.6 10.9 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.6 3.2 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.6 25.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.6 4.8 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.6 10.2 GO:0030316 osteoclast differentiation(GO:0030316)
0.6 7.5 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.6 24.1 GO:0046928 regulation of neurotransmitter secretion(GO:0046928) regulation of neurotransmitter transport(GO:0051588)
0.6 2.3 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.5 3.3 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.5 4.3 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.5 5.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.5 2.7 GO:0070650 actin filament bundle distribution(GO:0070650)
0.5 3.1 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.5 1.5 GO:0060959 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.5 1.5 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.5 13.7 GO:0070831 basement membrane assembly(GO:0070831)
0.5 21.0 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.5 5.6 GO:0035094 response to nicotine(GO:0035094)
0.5 1.8 GO:0090299 regulation of neural crest formation(GO:0090299)
0.4 2.6 GO:0055014 ventricular cardiac myofibril assembly(GO:0055005) atrial cardiac muscle cell development(GO:0055014)
0.4 17.4 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.4 2.4 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961)
0.4 6.3 GO:0036065 fucosylation(GO:0036065)
0.4 6.1 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.4 2.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.4 2.6 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.4 1.1 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.4 9.0 GO:0021884 forebrain neuron development(GO:0021884)
0.4 2.9 GO:0033292 T-tubule organization(GO:0033292)
0.3 1.7 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
0.3 3.1 GO:0003160 endocardium morphogenesis(GO:0003160)
0.3 7.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.3 1.9 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.3 2.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.3 3.2 GO:0097499 protein localization to nonmotile primary cilium(GO:0097499)
0.3 3.4 GO:0035675 neuromast hair cell development(GO:0035675)
0.3 2.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.3 2.7 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.3 10.3 GO:0072114 pronephros morphogenesis(GO:0072114)
0.3 12.6 GO:0001764 neuron migration(GO:0001764)
0.3 9.6 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.3 23.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.3 4.0 GO:0048016 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.3 18.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 3.5 GO:0032264 IMP salvage(GO:0032264)
0.2 2.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 2.8 GO:0071711 basement membrane organization(GO:0071711)
0.2 2.6 GO:0036368 cone photoresponse recovery(GO:0036368)
0.2 47.8 GO:0006813 potassium ion transport(GO:0006813)
0.2 1.9 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2 7.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2 6.7 GO:0050708 regulation of protein secretion(GO:0050708)
0.2 2.9 GO:0042407 cristae formation(GO:0042407)
0.2 1.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.2 2.6 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 4.4 GO:0003323 type B pancreatic cell development(GO:0003323)
0.2 6.8 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 3.8 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.2 1.6 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.2 24.5 GO:0050684 regulation of mRNA processing(GO:0050684)
0.2 0.9 GO:0090527 actin filament reorganization(GO:0090527)
0.2 4.0 GO:0070593 dendrite self-avoidance(GO:0070593)
0.2 3.8 GO:0007520 myoblast fusion(GO:0007520)
0.2 0.8 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.2 24.1 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.2 4.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.2 3.0 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 0.8 GO:0045974 miRNA metabolic process(GO:0010586) miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.6 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.1 2.1 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.1 33.9 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 2.5 GO:0019228 neuronal action potential(GO:0019228)
0.1 2.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 18.7 GO:0006909 phagocytosis(GO:0006909)
0.1 5.8 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 11.0 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.1 4.0 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.1 2.5 GO:0015671 oxygen transport(GO:0015671)
0.1 2.8 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 1.2 GO:0055062 phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.1 2.0 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.1 2.8 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 3.6 GO:0009306 protein secretion(GO:0009306)
0.1 0.5 GO:0017003 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.1 6.6 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 6.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 1.2 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 2.0 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.1 4.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 6.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 7.9 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.1 3.5 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 0.5 GO:0032366 intracellular sterol transport(GO:0032366)
0.1 0.9 GO:0050679 positive regulation of epithelial cell proliferation(GO:0050679)
0.1 2.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.7 GO:0043171 peptide catabolic process(GO:0043171)
0.1 7.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 3.0 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 8.8 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 1.5 GO:0060037 pharyngeal system development(GO:0060037)
0.0 2.6 GO:0016575 histone deacetylation(GO:0016575)
0.0 3.5 GO:0042552 myelination(GO:0042552)
0.0 1.1 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 5.8 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 0.3 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.0 3.3 GO:0050770 regulation of axonogenesis(GO:0050770)
0.0 0.8 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.4 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0097037 heme export(GO:0097037)
0.0 0.6 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 3.1 GO:0016579 protein deubiquitination(GO:0016579)
0.0 2.6 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 6.6 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 21.9 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 7.7 GO:0007015 actin filament organization(GO:0007015)
0.0 1.9 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 5.7 GO:0007409 axonogenesis(GO:0007409)
0.0 3.8 GO:0006399 tRNA metabolic process(GO:0006399)
0.0 1.0 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 1.6 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 1.7 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.2 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 3.8 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 22.5 GO:0070062 extracellular exosome(GO:0070062)
3.4 34.0 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
3.4 16.8 GO:0042584 chromaffin granule membrane(GO:0042584)
2.8 47.9 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
2.4 28.9 GO:0044295 axonal growth cone(GO:0044295)
2.4 16.7 GO:0043194 axon initial segment(GO:0043194)
2.3 18.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
1.9 46.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
1.8 16.4 GO:0033270 paranode region of axon(GO:0033270)
1.5 26.2 GO:0043209 myelin sheath(GO:0043209)
1.4 8.7 GO:0043083 synaptic cleft(GO:0043083)
1.1 24.9 GO:0043195 terminal bouton(GO:0043195)
0.9 14.0 GO:0030315 T-tubule(GO:0030315)
0.9 6.0 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.7 2.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.7 9.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.6 9.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.6 29.8 GO:0031941 filamentous actin(GO:0031941)
0.6 13.7 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.6 10.0 GO:0005801 cis-Golgi network(GO:0005801)
0.5 18.2 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.5 7.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.5 5.8 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.5 11.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.4 3.1 GO:0032019 mitochondrial cloud(GO:0032019)
0.3 8.9 GO:0035371 microtubule plus-end(GO:0035371)
0.3 4.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 2.9 GO:0016011 dystroglycan complex(GO:0016011)
0.3 14.3 GO:0032587 ruffle membrane(GO:0032587)
0.3 17.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 2.9 GO:0061617 MICOS complex(GO:0061617)
0.3 3.1 GO:0016580 Sin3 complex(GO:0016580)
0.2 20.6 GO:0030141 secretory granule(GO:0030141)
0.2 14.3 GO:0031225 anchored component of membrane(GO:0031225)
0.2 33.2 GO:0014069 postsynaptic density(GO:0014069)
0.2 7.9 GO:0035869 ciliary transition zone(GO:0035869)
0.2 0.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 16.3 GO:0005871 kinesin complex(GO:0005871)
0.2 10.0 GO:0042383 sarcolemma(GO:0042383)
0.2 8.3 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.2 2.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 17.2 GO:0043025 neuronal cell body(GO:0043025)
0.2 1.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 9.3 GO:0030018 Z disc(GO:0030018)
0.1 6.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.7 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 6.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 8.9 GO:0005882 intermediate filament(GO:0005882)
0.1 5.6 GO:0031201 SNARE complex(GO:0031201)
0.1 11.6 GO:0005802 trans-Golgi network(GO:0005802)
0.1 2.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 3.9 GO:0030427 site of polarized growth(GO:0030427)
0.1 1.5 GO:0015030 Cajal body(GO:0015030)
0.1 1.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 1.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 29.2 GO:0045202 synapse(GO:0045202)
0.1 27.4 GO:0031012 extracellular matrix(GO:0031012)
0.1 2.6 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 5.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 4.8 GO:0036064 ciliary basal body(GO:0036064)
0.1 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.1 30.9 GO:0043005 neuron projection(GO:0043005)
0.1 1.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 11.4 GO:0043235 receptor complex(GO:0043235)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 3.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 2.1 GO:0016592 mediator complex(GO:0016592)
0.0 2.6 GO:0000922 spindle pole(GO:0000922)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 18.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
2.3 47.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
2.2 6.5 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
1.6 11.2 GO:0030274 LIM domain binding(GO:0030274)
1.3 26.5 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
1.3 3.8 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
1.2 49.3 GO:0017075 syntaxin-1 binding(GO:0017075)
1.2 14.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
1.2 7.0 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
1.2 5.8 GO:0004689 phosphorylase kinase activity(GO:0004689)
1.1 14.0 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
1.0 30.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
1.0 28.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.9 4.4 GO:0060182 apelin receptor activity(GO:0060182)
0.9 37.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.8 21.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.8 4.0 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.8 4.7 GO:0019215 intermediate filament binding(GO:0019215)
0.8 12.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.8 44.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.8 2.3 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.7 15.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.7 8.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.7 11.8 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.7 14.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.7 5.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.7 2.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.6 7.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.6 1.7 GO:0005131 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.6 2.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.5 5.9 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.5 18.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.5 6.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.5 9.9 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.5 16.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.5 9.5 GO:0048185 activin binding(GO:0048185)
0.5 9.3 GO:0001671 ATPase activator activity(GO:0001671)
0.5 24.2 GO:0019905 syntaxin binding(GO:0019905)
0.4 9.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.4 6.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.4 24.1 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.4 10.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.4 4.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.4 13.7 GO:0017046 peptide hormone binding(GO:0017046)
0.4 1.9 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.4 16.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.4 2.5 GO:0098809 nitrite reductase activity(GO:0098809)
0.3 6.2 GO:0030552 cAMP binding(GO:0030552)
0.3 3.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 18.9 GO:0017124 SH3 domain binding(GO:0017124)
0.3 7.9 GO:0030371 translation repressor activity(GO:0030371)
0.3 2.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 3.5 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 2.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 4.8 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.3 9.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 1.8 GO:0070034 telomerase RNA binding(GO:0070034)
0.3 8.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 3.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 5.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 6.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 3.1 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 3.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 1.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 8.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 10.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 1.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 2.6 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 6.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 6.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 0.7 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.2 2.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 2.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 2.4 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.2 1.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 3.0 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 5.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 6.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 3.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 2.9 GO:0043236 laminin binding(GO:0043236)
0.1 1.7 GO:0016408 C-acyltransferase activity(GO:0016408)
0.1 14.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.5 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.1 19.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 12.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.6 GO:0070411 I-SMAD binding(GO:0070411)
0.1 3.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 2.4 GO:0098632 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.1 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 21.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 2.4 GO:0008013 beta-catenin binding(GO:0008013)
0.1 5.1 GO:0005516 calmodulin binding(GO:0005516)
0.1 1.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 3.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 18.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 23.1 GO:0046983 protein dimerization activity(GO:0046983)
0.0 8.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 14.1 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 8.8 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.8 GO:0042562 hormone binding(GO:0042562)
0.0 3.1 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 5.1 GO:0005125 cytokine activity(GO:0005125)
0.0 1.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 5.2 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 19.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.9 4.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.8 32.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.6 2.9 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.4 7.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.4 4.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.3 14.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.3 4.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 5.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 2.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 4.4 PID NOTCH PATHWAY Notch signaling pathway
0.1 2.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 2.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.1 PID MYC PATHWAY C-MYC pathway
0.0 5.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.2 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 47.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
2.7 46.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
1.2 8.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
1.2 22.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
1.0 14.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.9 18.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.9 11.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.8 18.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.7 6.5 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.7 9.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.7 5.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.5 6.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3 2.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 1.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 5.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 1.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 7.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 1.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 2.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 7.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 4.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 1.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 2.8 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 1.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 9.8 REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION Genes involved in Class I MHC mediated antigen processing & presentation
0.0 1.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors