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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for pax10+pax6a+pax6b

Z-value: 0.78

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Transcription factors associated with pax10+pax6a+pax6b

Gene Symbol Gene ID Gene Info
pax6b
ENSDARG00000045936 paired box 6b
pax10
ENSDARG00000053364 paired box 10
pax6a
ENSDARG00000103379 paired box 6a
pax10
ENSDARG00000111379 paired box 10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax10dr11_v1_chr3_+_32553714_32553714-0.372.9e-04Click!
pax6bdr11_v1_chr7_+_15872357_15872357-0.331.3e-03Click!
pax6adr11_v1_chr25_-_15049694_15049781-0.321.9e-03Click!

Activity profile of pax10+pax6a+pax6b motif

Sorted Z-values of pax10+pax6a+pax6b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr24_+_38306010 12.15 ENSDART00000143184
mybpc2b
myosin binding protein C, fast type b
chr10_-_8053385 10.41 ENSDART00000142714
si:ch211-251f6.7
si:ch211-251f6.7
chr10_-_8046764 9.81 ENSDART00000099031
zgc:136254
zgc:136254
chr10_-_8053753 7.00 ENSDART00000162289
si:ch211-251f6.7
si:ch211-251f6.7
chr7_+_38750871 6.45 ENSDART00000114238
ENSDART00000052325
ENSDART00000137001
f2
coagulation factor II (thrombin)
chr13_-_22862133 6.08 ENSDART00000138563
pbld2
phenazine biosynthesis-like protein domain containing 2
chr21_+_27382893 5.92 ENSDART00000005682
actn3a
actinin alpha 3a
chr2_+_6255434 5.73 ENSDART00000139429
zp3b
zona pellucida glycoprotein 3b
chr25_+_22320738 5.68 ENSDART00000073566
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr23_+_17926279 5.05 ENSDART00000012540
chia.4
chitinase, acidic.4
chr9_-_32847642 4.49 ENSDART00000121506
hpx
hemopexin
chr5_+_57924611 4.46 ENSDART00000050949
btg4
B-cell translocation gene 4
chr7_-_20582842 4.26 ENSDART00000169750
ENSDART00000111719
si:dkey-19b23.11
si:dkey-19b23.11
chr23_+_44611864 4.21 ENSDART00000145905
ENSDART00000132361
eno3
enolase 3, (beta, muscle)
chr9_+_8365398 4.03 ENSDART00000138713
ENSDART00000136847
si:dkey-90l23.2
si:dkey-90l23.2
chr3_+_43086548 3.73 ENSDART00000163579
si:dkey-43p13.5
si:dkey-43p13.5
chr6_+_23887314 3.58 ENSDART00000163188
znf648
zinc finger protein 648
chr14_-_1454045 3.26 ENSDART00000161460
pmt
phosphoethanolamine methyltransferase
chr13_-_20381485 3.06 ENSDART00000131351
si:ch211-270n8.1
si:ch211-270n8.1
chr8_+_52442622 3.00 ENSDART00000012758
zgc:77112
zgc:77112
chr9_-_1970071 2.92 ENSDART00000080608
hoxd10a
homeobox D10a
chr15_-_12270857 2.92 ENSDART00000170093
si:dkey-36i7.3
si:dkey-36i7.3
chr25_-_31423493 2.90 ENSDART00000027661
myod1
myogenic differentiation 1
chr1_+_5402476 2.75 ENSDART00000040204
tuba8l2
tubulin, alpha 8 like 2
chr10_+_25726694 2.74 ENSDART00000140308
ugt5d1
UDP glucuronosyltransferase 5 family, polypeptide D1
chr13_+_10945337 2.55 ENSDART00000091845
abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr15_+_1534644 2.53 ENSDART00000130413
smc4
structural maintenance of chromosomes 4
chr23_+_44614056 2.52 ENSDART00000188379
eno3
enolase 3, (beta, muscle)
chr9_+_23003208 2.52 ENSDART00000021060
eaf2
ELL associated factor 2
chr21_-_2322102 2.51 ENSDART00000162867
zgc:66483
zgc:66483
chr20_-_25486384 2.48 ENSDART00000141340
si:dkey-183n20.15
si:dkey-183n20.15
chr7_+_3357973 2.39 ENSDART00000172853
si:ch211-285c6.5
si:ch211-285c6.5
chr25_-_27842654 2.34 ENSDART00000154852
ENSDART00000156906
asb15a
ankyrin repeat and SOCS box containing 15a
chr18_+_62932 2.25 ENSDART00000052638
slc27a2a
solute carrier family 27 (fatty acid transporter), member 2a
chr14_-_858985 2.25 ENSDART00000148687
ENSDART00000149375
slc34a1a
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr18_+_14277003 2.25 ENSDART00000006628
zgc:173742
zgc:173742
chr19_+_30990815 2.23 ENSDART00000134645
sync
syncoilin, intermediate filament protein
chr19_-_4793263 2.19 ENSDART00000147510
ENSDART00000141336
ENSDART00000110551
ENSDART00000146684
st3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr21_-_25756119 2.19 ENSDART00000002341
cldnc
claudin c
chr12_+_25845494 2.13 ENSDART00000170582
glud1b
glutamate dehydrogenase 1b
chr10_-_17501528 2.09 ENSDART00000144847
slc2a11l
solute carrier family 2 (facilitated glucose transporter), member 11-like
chr13_-_10945288 2.07 ENSDART00000114315
ENSDART00000164667
ENSDART00000159482
abcg8
ATP-binding cassette, sub-family G (WHITE), member 8
chr14_-_14659023 2.01 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
nsdhl
NAD(P) dependent steroid dehydrogenase-like
chr9_-_42873700 2.00 ENSDART00000125953
ttn.1
titin, tandem duplicate 1
chr15_-_1745408 1.99 ENSDART00000182311
stx1a
syntaxin 1A (brain)
chr19_-_11238620 1.96 ENSDART00000148697
ENSDART00000149169
ssr2
signal sequence receptor, beta
chr16_+_13993285 1.94 ENSDART00000139130
ENSDART00000130353
si:dkey-85k15.7
fdps
si:dkey-85k15.7
farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
chr13_-_25196758 1.91 ENSDART00000184722
adka
adenosine kinase a
chr2_+_21000334 1.90 ENSDART00000062563
ENSDART00000147809
rreb1b
ras responsive element binding protein 1b
chr2_-_21349425 1.89 ENSDART00000171699
hhatla
hedgehog acyltransferase like, a
chr13_+_12671513 1.88 ENSDART00000010517
eif4eb
eukaryotic translation initiation factor 4eb
chr17_+_8799661 1.86 ENSDART00000105326
tonsl
tonsoku-like, DNA repair protein
chr4_-_18850799 1.86 ENSDART00000151844
mcat
malonyl CoA:ACP acyltransferase (mitochondrial)
chr20_+_1996202 1.80 ENSDART00000184143
CABZ01092781.1

chr1_+_51721851 1.77 ENSDART00000040397
prdx2
peroxiredoxin 2
chr1_+_12068800 1.74 ENSDART00000055566
xpa
xeroderma pigmentosum, complementation group A
chr8_+_52415603 1.71 ENSDART00000021604
ENSDART00000191424
gins4
GINS complex subunit 4 (Sld5 homolog)
chr25_-_37284370 1.71 ENSDART00000103222
nudt7
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr8_+_41038141 1.69 ENSDART00000075620
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr25_-_4148719 1.68 ENSDART00000112880
ENSDART00000023278
fads2
fatty acid desaturase 2
chr2_+_21048661 1.65 ENSDART00000156876
rreb1b
ras responsive element binding protein 1b
chr2_+_11031360 1.62 ENSDART00000180020
ENSDART00000145093
acot11a
acyl-CoA thioesterase 11a
chr24_-_36727922 1.62 ENSDART00000135142
si:ch73-334d15.1
si:ch73-334d15.1
chr18_+_45781516 1.62 ENSDART00000168840
rpl35a
ribosomal protein L35a
chr12_-_48671612 1.60 ENSDART00000007202
zgc:92749
zgc:92749
chr11_+_25619892 1.59 ENSDART00000146647
ENSDART00000033702
comtb
catechol-O-methyltransferase b
chr16_+_11779534 1.59 ENSDART00000133497
si:dkey-250k15.4
si:dkey-250k15.4
chr18_+_45781115 1.58 ENSDART00000151699
ENSDART00000179887
rpl35a
ribosomal protein L35a
chr11_-_3897067 1.50 ENSDART00000134858
rpn1
ribophorin I
chr16_-_13992646 1.45 ENSDART00000139623
si:dkey-85k15.6
si:dkey-85k15.6
chr7_+_59649746 1.45 ENSDART00000181067
rpl34
ribosomal protein L34
chr21_-_39566854 1.40 ENSDART00000020174
dynll2b
dynein, light chain, LC8-type 2b
chr15_-_14625373 1.35 ENSDART00000171841
slc5a2
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr10_-_25823258 1.34 ENSDART00000064327
ftr54
finTRIM family, member 54
chr9_+_40546677 1.34 ENSDART00000132911
vwc2l
von Willebrand factor C domain containing protein 2-like
chr25_+_37285737 1.31 ENSDART00000126879
tmed6
transmembrane p24 trafficking protein 6
chr15_-_44663712 1.31 ENSDART00000192124
CABZ01061894.1

chr7_-_45852270 1.30 ENSDART00000170224
shcbp1
SHC SH2-domain binding protein 1
chr13_-_39160018 1.30 ENSDART00000168795
col9a1b
collagen, type IX, alpha 1b
chr10_-_31015535 1.29 ENSDART00000146116
panx3
pannexin 3
chr8_+_41037541 1.29 ENSDART00000129344
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr13_-_39159810 1.25 ENSDART00000131508
col9a1b
collagen, type IX, alpha 1b
chr18_-_24988645 1.22 ENSDART00000136434
ENSDART00000085735
chd2
chromodomain helicase DNA binding protein 2
chr23_+_36052944 1.20 ENSDART00000103149
hoxc13a
homeobox C13a
chr4_-_17741513 1.18 ENSDART00000141680
mybpc1
myosin binding protein C, slow type
chr12_+_47794089 1.15 ENSDART00000160726
polr3a
polymerase (RNA) III (DNA directed) polypeptide A
chr11_-_11336986 1.15 ENSDART00000016677
zgc:77929
zgc:77929
chr22_+_8365905 1.13 ENSDART00000105945
si:dkey-19a16.11
si:dkey-19a16.11
chr24_+_26379441 1.12 ENSDART00000137786
si:ch211-230g15.5
si:ch211-230g15.5
chr9_+_31222026 1.10 ENSDART00000145573
clybl
citrate lyase beta like
chr11_-_45152912 1.09 ENSDART00000167540
ENSDART00000173050
ENSDART00000170795
afmid
arylformamidase
chr16_+_11779761 1.08 ENSDART00000140297
si:dkey-250k15.4
si:dkey-250k15.4
chr24_+_28561038 1.08 ENSDART00000147063
abca4a
ATP-binding cassette, sub-family A (ABC1), member 4a
chr21_+_23108420 1.08 ENSDART00000192394
ENSDART00000088459
htr3b
5-hydroxytryptamine (serotonin) receptor 3B
chr5_-_4204580 1.07 ENSDART00000049197
ENSDART00000132130
si:ch211-283g2.1
si:ch211-283g2.1
chr1_+_9199031 1.07 ENSDART00000092058
ENSDART00000182771
chtf18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr24_-_2381143 1.06 ENSDART00000144307
rreb1a
ras responsive element binding protein 1a
chr9_-_50000144 1.05 ENSDART00000123416
scn1a
sodium channel, voltage-gated, type I, alpha
chr18_-_14901437 1.02 ENSDART00000145842
ENSDART00000008035
trabd
TraB domain containing
chr10_+_26972755 1.02 ENSDART00000042162
tm7sf2
transmembrane 7 superfamily member 2
chr2_+_28453338 1.02 ENSDART00000020456
mmp15b
matrix metallopeptidase 15b
chr20_+_53474963 1.01 ENSDART00000138976
bub1ba
BUB1 mitotic checkpoint serine/threonine kinase Ba
chr8_+_37111643 1.01 ENSDART00000061336
ren
renin
chr17_+_8799451 1.00 ENSDART00000189814
ENSDART00000191577
tonsl
tonsoku-like, DNA repair protein
chr1_+_11107688 0.99 ENSDART00000109858
knstrn
kinetochore-localized astrin/SPAG5 binding protein
chr18_-_17513426 0.99 ENSDART00000146725
b3gnt9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr1_-_54706039 0.98 ENSDART00000083633
exosc1
exosome component 1
chr7_+_59649399 0.98 ENSDART00000123520
ENSDART00000040771
rpl34
ribosomal protein L34
chr3_-_23513155 0.97 ENSDART00000170200
BX682558.1

chr22_-_5006801 0.97 ENSDART00000106166
rx1
retinal homeobox gene 1
chr12_+_4900981 0.94 ENSDART00000171507
cd79b
CD79b molecule, immunoglobulin-associated beta
chr11_+_6115621 0.94 ENSDART00000165031
ENSDART00000027666
ENSDART00000161458
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
chr23_-_9925568 0.93 ENSDART00000081268
si:ch211-220i18.4
si:ch211-220i18.4
chr19_-_25114701 0.91 ENSDART00000149035
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr3_-_54607166 0.90 ENSDART00000021977
dnmt1
DNA (cytosine-5-)-methyltransferase 1
chr8_-_8489886 0.89 ENSDART00000183334
abt1
activator of basal transcription 1
chr23_-_27235403 0.89 ENSDART00000134418
si:dkey-157g16.6
si:dkey-157g16.6
chr4_-_5370468 0.89 ENSDART00000133423
ENSDART00000184963
si:dkey-14d8.1
si:dkey-14d8.1
chr21_+_43402794 0.89 ENSDART00000185572
frmd7
FERM domain containing 7
chr22_-_3182965 0.88 ENSDART00000158009
lonp1
lon peptidase 1, mitochondrial
chr24_+_39186940 0.87 ENSDART00000155817
spsb3b
splA/ryanodine receptor domain and SOCS box containing 3b
chr22_+_9091913 0.86 ENSDART00000186598
BX248395.1

chr14_-_30918662 0.86 ENSDART00000176631
si:ch211-126c2.4
si:ch211-126c2.4
chr11_-_45152702 0.85 ENSDART00000168066
afmid
arylformamidase
chr8_+_52442785 0.85 ENSDART00000189958
zgc:77112
zgc:77112
chr9_+_23900703 0.84 ENSDART00000127859
trim63b
tripartite motif containing 63b
chr22_+_22438783 0.84 ENSDART00000147825
kif14
kinesin family member 14
chr9_-_19583704 0.84 ENSDART00000053218
tmprss3a
transmembrane protease, serine 3a
chr17_-_12196865 0.84 ENSDART00000154694
kif28
kinesin family member 28
chr5_-_25072607 0.83 ENSDART00000145061
pnpla7b
patatin-like phospholipase domain containing 7b
chr21_-_1644414 0.83 ENSDART00000105736
ENSDART00000124904
zgc:152948
zgc:152948
chr7_-_58244220 0.82 ENSDART00000180450
unm_hu7910
un-named hu7910
chr20_+_37393134 0.82 ENSDART00000128321
adgrg6
adhesion G protein-coupled receptor G6
chr22_+_21398508 0.82 ENSDART00000089408
ENSDART00000186091
shdb
Src homology 2 domain containing transforming protein D, b
chr2_+_6991208 0.82 ENSDART00000182239
ddr2b
discoidin domain receptor tyrosine kinase 2b
chr20_-_3238110 0.81 ENSDART00000008077
spint1b
serine peptidase inhibitor, Kunitz type 1 b
chr19_-_20163197 0.79 ENSDART00000148179
ENSDART00000151646
fam221a
family with sequence similarity 221, member A
chr3_-_8542577 0.78 ENSDART00000183527
rbfox3b
RNA binding fox-1 homolog 3b
chr19_-_15192840 0.78 ENSDART00000151337
phactr4a
phosphatase and actin regulator 4a
chr14_-_12390724 0.78 ENSDART00000131343
magt1
magnesium transporter 1
chr2_-_32768951 0.77 ENSDART00000004712
bfsp2
beaded filament structural protein 2, phakinin
chr20_+_19119800 0.77 ENSDART00000151881
rp1l1b
retinitis pigmentosa 1-like 1b
chr3_-_26184018 0.77 ENSDART00000191604
si:ch211-11k18.4
si:ch211-11k18.4
chr6_-_58757131 0.77 ENSDART00000083582
soat2
sterol O-acyltransferase 2
chr11_-_165288 0.77 ENSDART00000108703
ENSDART00000173151
tegt
testis enhanced gene transcript (BAX inhibitor 1)
chr13_-_11378127 0.77 ENSDART00000158632
akt3a
v-akt murine thymoma viral oncogene homolog 3a
chr7_+_26545502 0.77 ENSDART00000140528
tnk1
tyrosine kinase, non-receptor, 1
chr5_-_55914268 0.76 ENSDART00000014049
wdr36
WD repeat domain 36
chr7_+_27250186 0.75 ENSDART00000150068
sox6
SRY (sex determining region Y)-box 6
chr21_-_3700334 0.75 ENSDART00000137844
atp8b1
ATPase phospholipid transporting 8B1
chr9_-_1949915 0.75 ENSDART00000190712
hoxd3a
homeobox D3a
chr23_+_38957738 0.75 ENSDART00000193480
ATP9A
ATPase phospholipid transporting 9A (putative)
chr24_-_26479841 0.75 ENSDART00000079984
rpl22l1
ribosomal protein L22-like 1
chr18_-_20466061 0.75 ENSDART00000060311
paqr5a
progestin and adipoQ receptor family member Va
chr4_+_18804317 0.74 ENSDART00000101043
slc26a3.2
solute carrier family 26 (anion exchanger), member 3, tandem duplicate 2
chr25_+_23280220 0.74 ENSDART00000153940
ptprjb.1
protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 1
chr4_-_13613148 0.74 ENSDART00000067164
ENSDART00000111247
irf5
interferon regulatory factor 5
chr20_-_47348116 0.74 ENSDART00000162087
ENSDART00000160769
ENSDART00000164484
dtnba
dystrobrevin, beta a
chr8_+_38417461 0.73 ENSDART00000132718
nkx6.3
NK6 homeobox 3
chr13_-_50200042 0.73 ENSDART00000074230
pkz
protein kinase containing Z-DNA binding domains
chr10_-_19497914 0.72 ENSDART00000132084
si:ch211-127i16.2
si:ch211-127i16.2
chr25_-_28926631 0.72 ENSDART00000112850
etfbkmt
electron transfer flavoprotein beta subunit lysine methyltransferase
chr9_-_746317 0.72 ENSDART00000129632
ENSDART00000130720
usp37
ubiquitin specific peptidase 37
chr9_-_2936017 0.72 ENSDART00000102823
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr10_-_45002196 0.71 ENSDART00000170767
ved
ventrally expressed dharma/bozozok antagonist
chr24_-_1010467 0.71 ENSDART00000114544
cdk13
cyclin-dependent kinase 13
chr12_-_19250854 0.70 ENSDART00000152844
cdc42ep1a
CDC42 effector protein (Rho GTPase binding) 1a
chr17_-_27266053 0.68 ENSDART00000110903
E2F2
si:ch211-160f23.5
chr1_+_55239160 0.67 ENSDART00000152318
si:ch211-286b5.2
si:ch211-286b5.2
chr6_-_39344259 0.67 ENSDART00000104074
zgc:158846
zgc:158846
chr11_+_12897004 0.67 ENSDART00000152007
si:dkey-11m19.5
si:dkey-11m19.5
chr12_-_16595406 0.66 ENSDART00000166798
si:dkey-239j18.2
si:dkey-239j18.2
chr17_-_36841981 0.66 ENSDART00000131566
myo6b
myosin VIb
chr7_-_1101071 0.66 ENSDART00000176053
dctn1a
dynactin 1a
chr25_-_7759453 0.65 ENSDART00000142439
ENSDART00000021577
phf21ab
PHD finger protein 21Ab
chr8_-_45729248 0.65 ENSDART00000187736
BX088696.1

chr23_+_38957472 0.65 ENSDART00000193836
ATP9A
ATPase phospholipid transporting 9A (putative)
chr25_+_30105628 0.65 ENSDART00000187704
si:ch211-147k10.5
si:ch211-147k10.5
chr25_-_10543682 0.65 ENSDART00000154262
tesmin
testis expressed metallothionein like protein
chr10_+_6625785 0.65 ENSDART00000148433
si:ch211-57m13.3
si:ch211-57m13.3
chr14_+_36454087 0.64 ENSDART00000180247
TENM3
si:dkey-237h12.3
chr5_-_26247973 0.64 ENSDART00000098527
erap1b
endoplasmic reticulum aminopeptidase 1b
chr24_+_37709191 0.64 ENSDART00000066558
decr2
2,4-dienoyl CoA reductase 2, peroxisomal
chr10_-_167782 0.62 ENSDART00000108780
erg
v-ets avian erythroblastosis virus E26 oncogene homolog
chr3_-_25118777 0.62 ENSDART00000188222
chadla
chondroadherin-like a
chr7_-_3850090 0.62 ENSDART00000113403
ENSDART00000137683
ENSDART00000049926
si:dkey-28d5.12
si:dkey-88n24.7
si:dkey-28d5.12
si:dkey-88n24.7
chr17_-_50018133 0.62 ENSDART00000112267
filip1a
filamin A interacting protein 1a
chr11_-_8262105 0.61 ENSDART00000173225
si:cabz01021066.1
si:cabz01021066.1
chr14_+_7902374 0.61 ENSDART00000113299
zgc:110843
zgc:110843
chr23_+_25292147 0.61 ENSDART00000131486
pa2g4b
proliferation-associated 2G4, b
chr1_+_33322174 0.61 ENSDART00000140435
mxra5a
matrix-remodelling associated 5a
chr9_+_7732714 0.61 ENSDART00000145853
si:ch1073-349o24.2
si:ch1073-349o24.2
chr2_+_17569644 0.61 ENSDART00000135823
pimr196
Pim proto-oncogene, serine/threonine kinase, related 196
chr4_+_56477160 0.60 ENSDART00000184152
si:ch211-237a4.2
si:ch211-237a4.2
chr16_-_5105295 0.60 ENSDART00000082071
ENSDART00000148955
ENSDART00000184700
ENSDART00000188127
bckdhb
branched chain keto acid dehydrogenase E1, beta polypeptide
chr8_-_45729758 0.59 ENSDART00000189329
BX088696.1

chr3_-_34717882 0.59 ENSDART00000151127
thraa
thyroid hormone receptor alpha a
chr12_-_35582683 0.59 ENSDART00000167933
sec24c
SEC24 homolog C, COPII coat complex component
chr10_-_22497980 0.58 ENSDART00000185549
CT573337.2

chr2_+_38731696 0.58 ENSDART00000181733
FQ377660.1

Network of associatons between targets according to the STRING database.

First level regulatory network of pax10+pax6a+pax6b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.7 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
1.0 2.9 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.9 6.5 GO:1900048 acute-phase response(GO:0006953) positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.8 6.7 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.6 1.9 GO:1903060 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.6 1.7 GO:0070914 UV-damage excision repair(GO:0070914) nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.5 1.5 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.5 5.1 GO:0006032 chitin catabolic process(GO:0006032)
0.4 3.0 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.4 2.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.3 5.7 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.3 1.9 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.3 1.9 GO:0044209 AMP salvage(GO:0044209)
0.3 2.1 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.3 5.4 GO:0051764 actin crosslink formation(GO:0051764)
0.3 1.7 GO:0009109 coenzyme catabolic process(GO:0009109)
0.3 0.8 GO:0060879 peripheral nervous system myelin formation(GO:0032290) semicircular canal fusion(GO:0060879)
0.2 1.9 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.2 0.7 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.2 1.4 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 1.6 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.2 1.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 2.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 0.8 GO:0034434 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.2 1.3 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.2 0.9 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.2 1.8 GO:0098869 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.2 3.9 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.2 0.8 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 1.0 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 4.6 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 2.9 GO:0031297 replication fork processing(GO:0031297)
0.1 2.2 GO:0006265 DNA topological change(GO:0006265)
0.1 0.5 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.4 GO:0006168 adenine salvage(GO:0006168) guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.1 2.3 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.1 2.0 GO:0048769 sarcomerogenesis(GO:0048769)
0.1 0.6 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.1 2.5 GO:0014812 muscle cell migration(GO:0014812)
0.1 0.8 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.3 GO:0046104 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.2 GO:0010359 regulation of anion channel activity(GO:0010359)
0.1 0.7 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.6 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998) regulation of fatty acid oxidation(GO:0046320)
0.1 0.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.8 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.2 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.1 0.4 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.1 1.0 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.7 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.3 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 1.0 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.4 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.3 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.7 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.1 0.6 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.1 0.6 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.6 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.9 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.6 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 2.0 GO:0001878 response to yeast(GO:0001878)
0.1 0.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.5 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.1 0.7 GO:0008105 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.0 1.0 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.3 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 2.6 GO:0048484 enteric nervous system development(GO:0048484)
0.0 1.0 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.3 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 2.8 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.6 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 3.5 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 4.3 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.8 GO:0060324 face development(GO:0060324)
0.0 11.5 GO:0060537 muscle tissue development(GO:0060537)
0.0 0.7 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 3.7 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.8 GO:0016233 telomere capping(GO:0016233)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.0 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 1.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.2 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.8 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 1.6 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 1.2 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 1.9 GO:0006413 translational initiation(GO:0006413)
0.0 0.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 1.5 GO:0007030 Golgi organization(GO:0007030)
0.0 0.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.4 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.7 GO:0048477 oogenesis(GO:0048477)
0.0 0.7 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.4 GO:0051014 actin filament severing(GO:0051014)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 1.2 GO:0031101 fin regeneration(GO:0031101)
0.0 0.1 GO:0032261 purine nucleotide salvage(GO:0032261)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.8 GO:0042461 photoreceptor cell development(GO:0042461)
0.0 0.1 GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902253) negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.7 27.2 GO:0000421 autophagosome membrane(GO:0000421)
0.4 1.7 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.4 2.9 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 1.7 GO:0000811 GINS complex(GO:0000811)
0.3 2.5 GO:0032783 ELL-EAF complex(GO:0032783)
0.2 0.9 GO:0019815 B cell receptor complex(GO:0019815)
0.2 3.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 0.6 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 0.5 GO:0005960 glycine cleavage complex(GO:0005960)
0.2 2.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 2.2 GO:0005903 brush border(GO:0005903)
0.1 0.6 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 1.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.7 GO:0036156 inner dynein arm(GO:0036156)
0.1 1.0 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.7 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 1.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.7 GO:0045095 keratin filament(GO:0045095)
0.1 1.4 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.1 1.3 GO:0005921 gap junction(GO:0005921)
0.1 0.8 GO:0070187 telosome(GO:0070187)
0.0 1.0 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 2.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 3.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 2.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 6.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.6 GO:0005871 kinesin complex(GO:0005871)
0.0 2.8 GO:0005840 ribosome(GO:0005840)
0.0 1.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 4.2 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 0.8 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.7 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.9 27.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.8 6.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.6 1.9 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.6 1.9 GO:0004061 arylformamidase activity(GO:0004061)
0.5 5.7 GO:0035804 structural constituent of egg coat(GO:0035804)
0.5 5.1 GO:0004568 chitinase activity(GO:0004568)
0.4 2.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.4 2.9 GO:0070888 E-box binding(GO:0070888)
0.4 1.6 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.4 1.9 GO:0004001 adenosine kinase activity(GO:0004001)
0.4 2.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.4 3.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.4 1.1 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.3 3.9 GO:2001069 glycogen binding(GO:2001069)
0.3 1.8 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 2.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 1.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.2 1.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.2 2.0 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 0.8 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 0.8 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.2 2.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 0.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 2.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.4 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.1 0.5 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.1 1.9 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 2.5 GO:0004312 fatty acid synthase activity(GO:0004312)
0.1 0.9 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.1 GO:0043142 DNA clamp loader activity(GO:0003689) single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) protein-DNA loading ATPase activity(GO:0033170) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 0.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 1.7 GO:0016289 CoA hydrolase activity(GO:0016289)
0.1 0.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 4.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.0 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.7 GO:0030332 cyclin binding(GO:0030332)
0.1 0.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 2.1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.1 0.5 GO:0036122 BMP binding(GO:0036122)
0.1 1.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 2.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 1.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.3 GO:0022829 wide pore channel activity(GO:0022829)
0.0 2.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.0 1.7 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.8 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 1.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.8 GO:0043236 laminin binding(GO:0043236)
0.0 7.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 6.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 4.3 GO:0016853 isomerase activity(GO:0016853)
0.0 0.6 GO:0015926 glucosidase activity(GO:0015926)
0.0 4.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 3.4 GO:0042626 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.7 GO:0003774 motor activity(GO:0003774)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 3.7 GO:0042393 histone binding(GO:0042393)
0.0 1.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 5.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 2.4 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.7 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 2.5 PID AURORA B PATHWAY Aurora B signaling
0.1 0.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 0.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.9 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.7 2.0 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.6 5.7 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.4 4.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 6.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 2.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 5.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 1.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 2.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.6 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 1.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 9.1 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism