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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for pbx1a+pbx1b+pbx2+pbx3a+pbx3b

Z-value: 2.65

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Transcription factors associated with pbx1a+pbx1b+pbx2+pbx3a+pbx3b

Gene Symbol Gene ID Gene Info
pbx3b
ENSDARG00000013615 pre-B-cell leukemia homeobox 3b
pbx2
ENSDARG00000019717 pre-B-cell leukemia homeobox 2
pbx3a
ENSDARG00000089262 pre-B-cell leukemia homeobox 3a
pbx1a
ENSDARG00000100494 pre-B-cell leukemia homeobox 1a
pbx1b
ENSDARG00000101131 pre-B-cell leukemia homeobox 1b
pbx3b
ENSDARG00000110194 pre-B-cell leukemia homeobox 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pbx3bdr11_v1_chr8_-_34065573_340655730.667.9e-13Click!
pbx1bdr11_v1_chr6_+_2271559_22715590.617.8e-11Click!
pbx1adr11_v1_chr2_-_18830722_188307830.602.4e-10Click!
pbx3adr11_v1_chr5_-_5394335_53944680.422.8e-05Click!
pbx2dr11_v1_chr16_+_48631412_48631412-0.278.5e-03Click!

Activity profile of pbx1a+pbx1b+pbx2+pbx3a+pbx3b motif

Sorted Z-values of pbx1a+pbx1b+pbx2+pbx3a+pbx3b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_62380146 41.50 ENSDART00000155853
gprc5ba
G protein-coupled receptor, class C, group 5, member Ba
chr22_-_13851297 36.37 ENSDART00000080306
s100b
S100 calcium binding protein, beta (neural)
chr2_-_44283554 26.20 ENSDART00000184684
mpz
myelin protein zero
chr18_+_13792490 23.72 ENSDART00000136754
cdh13
cadherin 13, H-cadherin (heart)
chr9_-_44295071 21.83 ENSDART00000011837
neurod1
neuronal differentiation 1
chr2_-_44946094 21.38 ENSDART00000036997
camk2n1a
calcium/calmodulin-dependent protein kinase II inhibitor 1a
chr20_-_29420713 21.23 ENSDART00000147464
ryr3
ryanodine receptor 3
chr25_+_21324588 21.17 ENSDART00000151842
lrrn3a
leucine rich repeat neuronal 3a
chr1_-_6494384 20.61 ENSDART00000109356
klf7a
Kruppel-like factor 7a
chr9_+_27411502 20.34 ENSDART00000143994
si:dkey-193n17.9
si:dkey-193n17.9
chr6_+_14949950 19.94 ENSDART00000149202
ENSDART00000149949
pou3f3b
POU class 3 homeobox 3b
chr14_+_33458294 19.80 ENSDART00000075278
atp1b4
ATPase Na+/K+ transporting subunit beta 4
chr2_-_19109304 19.68 ENSDART00000168028
si:dkey-225f23.5
si:dkey-225f23.5
chr6_+_48618512 18.68 ENSDART00000111190
FAM19A3
si:dkey-238f9.1
chr19_-_30562648 18.30 ENSDART00000171006
hpcal4
hippocalcin like 4
chr11_+_14622379 18.11 ENSDART00000112589
efna2b
ephrin-A2b
chr10_+_34426256 17.42 ENSDART00000102566
nbeaa
neurobeachin a
chr17_-_15528597 17.30 ENSDART00000150232
fyna
FYN proto-oncogene, Src family tyrosine kinase a
chr15_-_12545683 16.80 ENSDART00000162807
scn2b
sodium channel, voltage-gated, type II, beta
chr21_+_11468934 16.80 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
grin1a
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr24_+_29382109 16.76 ENSDART00000184620
ENSDART00000188414
ENSDART00000186132
ENSDART00000191489
ntng1a
netrin g1a
chr19_-_9829965 16.70 ENSDART00000136842
ENSDART00000142766
cacng8a
calcium channel, voltage-dependent, gamma subunit 8a
chr21_+_30563115 16.55 ENSDART00000028566
si:ch211-200p22.4
si:ch211-200p22.4
chr15_-_34214440 16.41 ENSDART00000167052
etv1
ets variant 1
chr4_+_9669717 16.28 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr12_-_14922955 16.25 ENSDART00000002078
neurod2
neurogenic differentiation 2
chr20_-_34868814 16.17 ENSDART00000153049
stmn4
stathmin-like 4
chr24_+_41931585 15.86 ENSDART00000130310
epb41l3a
erythrocyte membrane protein band 4.1-like 3a
chr10_-_27046639 15.73 ENSDART00000041841
cnih2
cornichon family AMPA receptor auxiliary protein 2
chr19_+_46158078 15.69 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr2_-_24996441 15.64 ENSDART00000144795
slc35g2a
solute carrier family 35, member G2a
chr19_+_37857936 15.54 ENSDART00000189289
nxph1
neurexophilin 1
chr23_-_30431333 15.44 ENSDART00000146633
camta1a
calmodulin binding transcription activator 1a
chr4_-_27301356 15.38 ENSDART00000100444
fam19a5a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr7_-_38633867 15.20 ENSDART00000137424
c1qtnf4
C1q and TNF related 4
chr10_+_37500234 14.92 ENSDART00000132096
ENSDART00000099473
msi2a
musashi RNA-binding protein 2a
chr16_+_7626535 14.92 ENSDART00000182670
ENSDART00000065514
ENSDART00000150212
stx12l
syntaxin 12, like
chr23_+_45579497 14.83 ENSDART00000110381
egr4
early growth response 4
chr4_-_5291256 14.72 ENSDART00000150864
SNAP91 (1 of many)
si:ch211-214j24.9
chr7_-_30174882 14.55 ENSDART00000110409
frmd5
FERM domain containing 5
chr24_+_29381946 14.38 ENSDART00000189551
ntng1a
netrin g1a
chr3_+_35005062 14.29 ENSDART00000181163
prkcbb
protein kinase C, beta b
chr1_+_32528097 14.14 ENSDART00000128317
nlgn4a
neuroligin 4a
chr2_-_10192459 13.73 ENSDART00000128535
ENSDART00000017173
dmbx1a
diencephalon/mesencephalon homeobox 1a
chr5_+_33301005 13.53 ENSDART00000006021
usp20
ubiquitin specific peptidase 20
chr23_+_28582865 13.45 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr14_+_22591624 13.20 ENSDART00000108987
gfra4b
GDNF family receptor alpha 4b
chr24_+_32472155 13.17 ENSDART00000098859
neurod6a
neuronal differentiation 6a
chr5_-_13766651 12.98 ENSDART00000134064
mxd1
MAX dimerization protein 1
chr21_-_38619305 12.83 ENSDART00000139178
slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr14_-_47314011 12.81 ENSDART00000178523
fstl5
follistatin-like 5
chr16_+_41873708 12.68 ENSDART00000084631
ENSDART00000084639
ENSDART00000058611
scn1ba
sodium channel, voltage-gated, type I, beta a
chr1_+_12763461 12.50 ENSDART00000159226
ENSDART00000180121
pcdh10a
protocadherin 10a
chr13_+_11436130 12.44 ENSDART00000169895
zbtb18
zinc finger and BTB domain containing 18
chr22_-_38607504 12.27 ENSDART00000164609
si:ch211-126j24.1
si:ch211-126j24.1
chr25_-_16826219 12.16 ENSDART00000191299
ENSDART00000188504
dyrk4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr23_+_23182037 12.13 ENSDART00000137353
klhl17
kelch-like family member 17
chr15_+_47161917 11.99 ENSDART00000167860
gap43
growth associated protein 43
chr23_+_41799748 11.95 ENSDART00000144257
pdyn
prodynorphin
chr9_+_6009077 11.92 ENSDART00000057484
st6gal2a
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2a
chr20_-_47731768 11.77 ENSDART00000031167
tfap2d
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr20_+_29743904 11.72 ENSDART00000146366
ENSDART00000153154
kidins220b
kinase D-interacting substrate 220b
chr17_+_52822831 11.70 ENSDART00000193368
meis2a
Meis homeobox 2a
chr5_+_59278193 11.51 ENSDART00000160025
rasa4
RAS p21 protein activator 4
chr18_-_26675699 11.47 ENSDART00000113280
FRMD5
si:ch211-69m14.1
chr8_+_7144066 11.40 ENSDART00000146306
slc6a6a
solute carrier family 6 (neurotransmitter transporter), member 6a
chr3_+_32526263 11.37 ENSDART00000150897
si:ch73-367p23.2
si:ch73-367p23.2
chr19_+_8144556 11.36 ENSDART00000027274
ENSDART00000147218
efna3a
ephrin-A3a
chr17_+_52822422 11.34 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr11_-_101758 11.32 ENSDART00000173015
elmo2
engulfment and cell motility 2
chr23_+_19590006 11.30 ENSDART00000021231
slmapb
sarcolemma associated protein b
chr2_-_3678029 11.05 ENSDART00000146861
mmp16b
matrix metallopeptidase 16b (membrane-inserted)
chr11_+_25129013 11.03 ENSDART00000132879
ndrg3a
ndrg family member 3a
chr14_+_45883687 10.99 ENSDART00000114790
flrt1b
fibronectin leucine rich transmembrane protein 1b
chr3_+_32526799 10.87 ENSDART00000185755
si:ch73-367p23.2
si:ch73-367p23.2
chr21_-_34658266 10.85 ENSDART00000023038
dacha
dachshund a
chr22_-_23253481 10.85 ENSDART00000054807
lhx9
LIM homeobox 9
chr11_+_28218141 10.85 ENSDART00000043756
ephb2b
eph receptor B2b
chr1_+_40034061 10.81 ENSDART00000011727
ccdc149b
coiled-coil domain containing 149b
chr14_+_29609245 10.75 ENSDART00000043058
TENM2
si:dkey-34l15.2
chr16_-_13730152 10.69 ENSDART00000138772
ttyh1
tweety family member 1
chr24_+_37370064 10.54 ENSDART00000185870
si:ch211-183d21.3
si:ch211-183d21.3
chr15_-_30505607 10.48 ENSDART00000155212
msi2b
musashi RNA-binding protein 2b
chr6_-_6423885 10.46 ENSDART00000092257
si:ch211-194e18.2
si:ch211-194e18.2
chr3_-_1190132 10.44 ENSDART00000149709
smdt1a
single-pass membrane protein with aspartate-rich tail 1a
chr9_-_5046315 10.38 ENSDART00000179087
ENSDART00000109954
nr4a2a
nuclear receptor subfamily 4, group A, member 2a
chr5_+_19320554 10.36 ENSDART00000165119
rusc2
RUN and SH3 domain containing 2
chr7_-_69636502 10.33 ENSDART00000126739
tspan5a
tetraspanin 5a
chr15_-_19250543 10.31 ENSDART00000092705
ENSDART00000138895
igsf9ba
immunoglobulin superfamily, member 9Ba
chr5_+_65536095 10.28 ENSDART00000189898
si:dkey-21e5.1
si:dkey-21e5.1
chr16_-_563235 10.26 ENSDART00000016303
irx2a
iroquois homeobox 2a
chr2_+_59015878 10.21 ENSDART00000148816
ENSDART00000122795
si:ch1073-391i24.1
si:ch1073-391i24.1
chr16_+_50434668 10.16 ENSDART00000193500
IGLON5
zgc:110372
chr15_+_36115955 10.07 ENSDART00000032702
sst1.2
somatostatin 1, tandem duplicate 2
chr12_+_25600685 9.98 ENSDART00000077157
six3b
SIX homeobox 3b
chr10_+_20108557 9.98 ENSDART00000142708
dmtn
dematin actin binding protein
chr2_-_50298337 9.97 ENSDART00000155125
cntnap2b
contactin associated protein like 2b
chr13_+_28702104 9.91 ENSDART00000135481
si:ch211-67n3.9
si:ch211-67n3.9
chr14_+_32022272 9.87 ENSDART00000105760
zic6
zic family member 6
chr9_-_48937240 9.84 ENSDART00000075627
cers6
ceramide synthase 6
chr2_-_30770736 9.81 ENSDART00000131230
rgs20
regulator of G protein signaling 20
chr13_-_10261383 9.80 ENSDART00000080808
six3a
SIX homeobox 3a
chr11_-_17713987 9.71 ENSDART00000090401
fam19a4b
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4b
chr20_-_53996193 9.66 ENSDART00000004756
hsp90aa1.1
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1
chr2_-_44038698 9.58 ENSDART00000079582
ENSDART00000146804
kirrel1b
kirre like nephrin family adhesion molecule 1b
chr1_+_51312752 9.56 ENSDART00000063938
mast1a
microtubule associated serine/threonine kinase 1a
chr6_+_2271559 9.55 ENSDART00000165223
pbx1b
pre-B-cell leukemia homeobox 1b
chr20_-_20821783 9.49 ENSDART00000152577
ENSDART00000027603
ENSDART00000145601
ckbb
creatine kinase, brain b
chr17_+_24318753 9.49 ENSDART00000064083
otx1
orthodenticle homeobox 1
chr5_+_70155935 9.47 ENSDART00000165570
rgs3a
regulator of G protein signaling 3a
chr16_+_23598908 9.42 ENSDART00000131627
kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr8_-_33114202 9.36 ENSDART00000098840
ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr1_+_9557212 9.30 ENSDART00000111131
elfn1b
extracellular leucine-rich repeat and fibronectin type III domain containing 1b
chr2_-_31735142 9.30 ENSDART00000130903
ralyl
RALY RNA binding protein like
chr1_+_14073891 9.23 ENSDART00000021693
ank2a
ankyrin 2a, neuronal
chr12_+_16233077 9.22 ENSDART00000152409
mpp3b
membrane protein, palmitoylated 3b (MAGUK p55 subfamily member 3)
chr17_-_43287290 9.15 ENSDART00000156885
EML5
si:dkey-1f12.3
chr15_+_5901970 9.14 ENSDART00000114134
wrb
tryptophan rich basic protein
chr1_+_45217425 9.13 ENSDART00000179983
ENSDART00000074683
EVI5L
si:ch211-239f4.1
chr6_+_4872883 9.13 ENSDART00000186730
ENSDART00000092290
ENSDART00000151674
pcdh9
protocadherin 9
chr4_-_27398385 9.10 ENSDART00000142117
ENSDART00000150553
ENSDART00000182746
fam19a5a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr20_+_28434196 9.03 ENSDART00000034245
dpf3
D4, zinc and double PHD fingers, family 3
chr14_-_52521460 8.85 ENSDART00000172110
GPR151
G protein-coupled receptor 151
chr8_+_13849999 8.83 ENSDART00000143784
doc2d
double C2-like domains, delta
chr14_-_2318590 8.72 ENSDART00000192735
pcdh2ab8
protocadherin 2 alpha b 8
chr6_+_43903209 8.65 ENSDART00000006435
gpr27
G protein-coupled receptor 27
chr21_-_12119711 8.62 ENSDART00000131538
celf4
CUGBP, Elav-like family member 4
chr10_+_43797130 8.56 ENSDART00000027242
nr2f1b
nuclear receptor subfamily 2, group F, member 1b
chr11_+_25010491 8.55 ENSDART00000167285
zgc:92107
zgc:92107
chr12_+_15008582 8.39 ENSDART00000003847
mylpfb
myosin light chain, phosphorylatable, fast skeletal muscle b
chr19_-_28130658 8.38 ENSDART00000079114
irx1b
iroquois homeobox 1b
chr21_-_35832548 8.35 ENSDART00000180840
sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr10_-_31220558 8.34 ENSDART00000134866
pknox2
pbx/knotted 1 homeobox 2
chr10_+_20128267 8.33 ENSDART00000064615
dmtn
dematin actin binding protein
chr5_-_69482891 8.31 ENSDART00000109487
CABZ01032476.1

chr15_-_34213898 8.27 ENSDART00000191945
ENSDART00000186089
etv1
ets variant 1
chr22_+_34430310 8.21 ENSDART00000109860
amigo3
adhesion molecule with Ig-like domain 3
chr7_+_22718251 8.21 ENSDART00000027718
ENSDART00000143341
fxr2
fragile X mental retardation, autosomal homolog 2
chr24_-_28381404 8.13 ENSDART00000148406
prkag2a
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr23_+_41800052 8.13 ENSDART00000141484
pdyn
prodynorphin
chr12_+_3078221 8.08 ENSDART00000148835
ENSDART00000149427
sgca
sarcoglycan, alpha
chr7_+_61906903 8.08 ENSDART00000108540
tdrd7b
tudor domain containing 7 b
chr10_-_21046917 8.03 ENSDART00000091004
pcdh1a
protocadherin 1a
chr7_-_27696958 7.98 ENSDART00000173470
calca
calcitonin/calcitonin-related polypeptide, alpha
chr22_-_15385442 7.91 ENSDART00000090975
tmem264
transmembrane protein 264
chr2_-_53896300 7.88 ENSDART00000161221
capsla
calcyphosine-like a
chr15_+_16521785 7.81 ENSDART00000062191
galnt17
polypeptide N-acetylgalactosaminyltransferase 17
chr16_-_31933740 7.79 ENSDART00000125411
si:ch1073-90m23.1
si:ch1073-90m23.1
chr25_+_13791627 7.77 ENSDART00000159278
zgc:92873
zgc:92873
chr13_-_21739142 7.69 ENSDART00000078460
si:dkey-191g9.5
si:dkey-191g9.5
chr1_-_44704261 7.63 ENSDART00000133210
si:dkey-28b4.8
si:dkey-28b4.8
chr18_+_50907675 7.61 ENSDART00000159950
si:ch1073-450f2.1
si:ch1073-450f2.1
chr2_-_48171441 7.61 ENSDART00000123040
pfkpb
phosphofructokinase, platelet b
chr13_+_22249636 7.60 ENSDART00000108472
ENSDART00000173123
synpo2la
synaptopodin 2-like a
chr5_+_68112194 7.54 ENSDART00000162468
CABZ01083937.1

chr7_+_36041509 7.54 ENSDART00000162850
irx3a
iroquois homeobox 3a
chr17_-_20430177 7.52 ENSDART00000114236
sorcs3b
sortilin related VPS10 domain containing receptor 3b
chr7_+_23457803 7.49 ENSDART00000024191
htr2cl1
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1
chr10_-_42039128 7.34 ENSDART00000184046
ENSDART00000144919
car15
carbonic anhydrase 15
chr20_+_26095530 7.30 ENSDART00000139350
syne1a
spectrin repeat containing, nuclear envelope 1a
chr4_-_16124417 7.23 ENSDART00000128079
ENSDART00000077664
atp2b1a
ATPase plasma membrane Ca2+ transporting 1a
chr18_+_16963881 7.19 ENSDART00000147583
si:ch211-242e8.1
si:ch211-242e8.1
chr16_+_14710436 7.19 ENSDART00000027982
col14a1a
collagen, type XIV, alpha 1a
chr15_-_19677511 7.18 ENSDART00000043743
si:dkey-4p15.3
si:dkey-4p15.3
chr6_+_52804267 7.16 ENSDART00000065681
matn4
matrilin 4
chr15_+_40665310 7.10 ENSDART00000154187
ENSDART00000042082
fat3a
FAT atypical cadherin 3a
chr20_-_53981626 7.10 ENSDART00000023550
hsp90aa1.2
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2
chr10_+_34426571 7.10 ENSDART00000144529
nbeaa
neurobeachin a
chr8_+_25247245 6.98 ENSDART00000045798
ampd2b
adenosine monophosphate deaminase 2b
chr19_+_26718074 6.93 ENSDART00000134455
zgc:100906
zgc:100906
chr3_+_40407352 6.92 ENSDART00000155112
tnrc18
trinucleotide repeat containing 18
chr16_+_11151699 6.85 ENSDART00000140674
cicb
capicua transcriptional repressor b
chr10_+_26515946 6.84 ENSDART00000134276
synj1
synaptojanin 1
chr15_+_18863875 6.84 ENSDART00000062603
cadm1b
cell adhesion molecule 1b
chr11_+_3005536 6.80 ENSDART00000174539
cpne5b
copine Vb
chr3_+_62353650 6.80 ENSDART00000112428
iqck
IQ motif containing K
chr2_-_7431590 6.79 ENSDART00000185699
asip2b
agouti signaling protein, nonagouti homolog (mouse) 2b
chr17_-_38442362 6.78 ENSDART00000085438
rps6ka5
ribosomal protein S6 kinase, polypeptide 5
chr14_+_11762991 6.77 ENSDART00000110004
frmpd3
FERM and PDZ domain containing 3
chr3_+_16724614 6.76 ENSDART00000182135
gys1
glycogen synthase 1 (muscle)
chr5_-_36837846 6.72 ENSDART00000032481
ckma
creatine kinase, muscle a
chr17_+_28340138 6.69 ENSDART00000033943
mdga2a
MAM domain containing glycosylphosphatidylinositol anchor 2a
chr8_+_1433647 6.68 ENSDART00000160797
efna5b
ephrin-A5b
chr20_-_44575103 6.67 ENSDART00000192573
ubxn2a
UBX domain protein 2A
chr5_+_59278593 6.65 ENSDART00000097374
rasa4
RAS p21 protein activator 4
chr11_+_3006124 6.65 ENSDART00000126071
cpne5b
copine Vb
chr8_-_1051438 6.59 ENSDART00000067093
ENSDART00000170737
smyd1b
SET and MYND domain containing 1b
chr11_-_42554290 6.54 ENSDART00000130573
atp6ap1la
ATPase H+ transporting accessory protein 1 like a
chr1_-_50611031 6.52 ENSDART00000148285
ppm1k
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr4_-_19883985 6.50 ENSDART00000014440
cacna2d1a
calcium channel, voltage-dependent, alpha 2/delta subunit 1a
chr2_-_54039293 6.47 ENSDART00000166013
abhd8a
abhydrolase domain containing 8a
chr14_-_689841 6.46 ENSDART00000125969
ube2ka
ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast)
chr4_-_9764767 6.40 ENSDART00000164328
ENSDART00000147699
mical3b
microtubule associated monooxygenase, calponin and LIM domain containing 3b
chr1_-_57280585 6.34 ENSDART00000152220
si:dkey-27j5.5
si:dkey-27j5.5
chr21_-_39670375 6.28 ENSDART00000151567
sgk494b
uncharacterized serine/threonine-protein kinase SgK494b
chr8_-_9570511 6.24 ENSDART00000044000
plxna3
plexin A3
chr19_+_712127 6.24 ENSDART00000093281
ENSDART00000180002
ENSDART00000146050
fhod3a
formin homology 2 domain containing 3a
chr2_+_5446087 6.18 ENSDART00000155165
dusp28
dual specificity phosphatase 28
chr21_-_23746916 6.10 ENSDART00000017229
ncam1a
neural cell adhesion molecule 1a
chr1_+_45217619 6.10 ENSDART00000125037
EVI5L
si:ch211-239f4.1

Network of associatons between targets according to the STRING database.

First level regulatory network of pbx1a+pbx1b+pbx2+pbx3a+pbx3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 16.2 GO:0060074 synapse maturation(GO:0060074)
3.6 10.8 GO:0097378 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
3.3 16.5 GO:0015709 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
3.0 23.7 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
2.4 9.7 GO:1903428 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
2.3 6.8 GO:0032369 negative regulation of lipid transport(GO:0032369)
2.2 6.7 GO:0021611 facial nerve formation(GO:0021611)
2.2 6.7 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
2.2 17.3 GO:0034334 adherens junction maintenance(GO:0034334)
2.1 20.8 GO:0021631 optic nerve morphogenesis(GO:0021631)
2.0 6.1 GO:0021961 posterior commissure morphogenesis(GO:0021961)
2.0 10.0 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
2.0 13.8 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
1.9 9.5 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
1.7 15.1 GO:1904861 excitatory synapse assembly(GO:1904861)
1.7 5.0 GO:0044406 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
1.5 16.3 GO:0061621 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
1.5 5.9 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
1.4 7.2 GO:0034505 tooth mineralization(GO:0034505)
1.4 5.7 GO:0010226 response to lithium ion(GO:0010226)
1.2 16.2 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
1.2 34.9 GO:0070831 basement membrane assembly(GO:0070831)
1.2 34.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
1.2 4.7 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
1.2 20.2 GO:0039014 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
1.2 10.4 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
1.1 32.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
1.1 5.6 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
1.1 5.5 GO:0032289 central nervous system myelin formation(GO:0032289)
1.1 19.7 GO:0097324 melanocyte migration(GO:0097324)
1.0 5.2 GO:0046677 response to antibiotic(GO:0046677)
1.0 5.2 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
1.0 6.2 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
1.0 5.2 GO:1901910 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
1.0 5.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
1.0 3.0 GO:0015074 DNA integration(GO:0015074)
1.0 31.9 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
1.0 16.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
1.0 56.8 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.9 7.6 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.9 16.1 GO:0035476 angioblast cell migration(GO:0035476)
0.9 9.9 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.9 12.3 GO:0048769 sarcomerogenesis(GO:0048769)
0.8 5.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.8 13.3 GO:0016198 axon choice point recognition(GO:0016198)
0.8 19.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.8 7.6 GO:0060612 adipose tissue development(GO:0060612)
0.7 5.2 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.7 2.9 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.7 3.7 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.7 5.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.7 7.0 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.7 8.4 GO:0007525 somatic muscle development(GO:0007525)
0.7 3.5 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.7 10.3 GO:0061074 regulation of neural retina development(GO:0061074)
0.7 4.1 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.7 5.3 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.7 4.0 GO:0035881 amacrine cell differentiation(GO:0035881)
0.7 10.5 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.7 10.5 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.7 3.9 GO:0036268 swimming(GO:0036268)
0.6 4.5 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.6 4.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.6 10.8 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.6 4.5 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.6 9.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.6 1.9 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.6 19.8 GO:0030817 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.6 13.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.6 1.7 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.6 13.1 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.6 31.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.6 16.5 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.6 11.0 GO:0039022 pronephric duct development(GO:0039022) nephric duct development(GO:0072176)
0.5 6.5 GO:0035264 multicellular organism growth(GO:0035264)
0.5 2.1 GO:0090113 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.5 4.7 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.5 9.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.5 3.1 GO:0021654 rhombomere boundary formation(GO:0021654)
0.5 1.0 GO:0065001 specification of axis polarity(GO:0065001)
0.5 2.5 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.5 7.0 GO:0032264 IMP salvage(GO:0032264)
0.5 2.9 GO:0007603 phototransduction, visible light(GO:0007603)
0.5 8.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.5 15.7 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.5 4.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.5 1.4 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.5 1.9 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.5 5.5 GO:0009584 detection of visible light(GO:0009584)
0.5 3.2 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.4 3.1 GO:0045981 positive regulation of nucleotide metabolic process(GO:0045981) positive regulation of purine nucleotide metabolic process(GO:1900544)
0.4 18.1 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.4 8.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.4 3.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.4 6.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.4 4.6 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.4 4.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.4 1.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.4 11.2 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.4 9.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.4 2.7 GO:0021982 pineal gland development(GO:0021982)
0.4 5.8 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.4 2.3 GO:0003272 endocardial cushion formation(GO:0003272)
0.4 6.9 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.4 0.8 GO:0021794 thalamus development(GO:0021794)
0.4 15.2 GO:1902749 regulation of cell cycle G2/M phase transition(GO:1902749)
0.4 1.5 GO:0070987 error-free translesion synthesis(GO:0070987)
0.4 3.8 GO:0050819 negative regulation of coagulation(GO:0050819)
0.4 7.0 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.4 11.4 GO:0072348 sulfur compound transport(GO:0072348)
0.4 8.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.3 25.2 GO:0007416 synapse assembly(GO:0007416)
0.3 1.4 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.3 5.7 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.3 5.5 GO:0006265 DNA topological change(GO:0006265)
0.3 2.5 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.3 0.9 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.3 2.1 GO:0044211 CTP salvage(GO:0044211)
0.3 8.0 GO:0055064 chloride ion homeostasis(GO:0055064)
0.3 1.0 GO:1904590 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.3 13.2 GO:0000187 activation of MAPK activity(GO:0000187)
0.3 7.7 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.3 1.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.3 7.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.2 6.2 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.2 2.4 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.2 22.5 GO:0009880 embryonic pattern specification(GO:0009880)
0.2 6.8 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.2 9.3 GO:0032400 melanosome localization(GO:0032400)
0.2 3.1 GO:0090316 positive regulation of intracellular protein transport(GO:0090316)
0.2 8.7 GO:0042593 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.2 5.4 GO:0043486 histone exchange(GO:0043486)
0.2 4.5 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 4.1 GO:0043049 otic placode formation(GO:0043049)
0.2 3.6 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.2 13.4 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.2 20.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.2 8.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 41.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 8.7 GO:0030641 regulation of cellular pH(GO:0030641)
0.2 1.4 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.2 12.5 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.2 14.9 GO:0048278 vesicle docking(GO:0048278)
0.2 5.2 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.2 1.2 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.2 4.7 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.2 1.8 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.2 1.3 GO:0006857 oligopeptide transport(GO:0006857)
0.2 2.3 GO:0000272 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.2 1.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 11.4 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.1 33.2 GO:0006813 potassium ion transport(GO:0006813)
0.1 4.9 GO:0045332 phospholipid translocation(GO:0045332)
0.1 24.5 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 0.8 GO:0006574 valine catabolic process(GO:0006574)
0.1 3.4 GO:0010458 exit from mitosis(GO:0010458)
0.1 2.0 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 1.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.9 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 6.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 1.3 GO:0098887 neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.1 0.8 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.1 0.3 GO:0019408 polyprenol biosynthetic process(GO:0016094) dolichol biosynthetic process(GO:0019408)
0.1 1.8 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 2.0 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 3.0 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 1.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 1.4 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 13.6 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 3.8 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 1.8 GO:0046660 female sex differentiation(GO:0046660)
0.1 3.2 GO:0098534 centriole assembly(GO:0098534)
0.1 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 2.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 4.1 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 10.8 GO:0006936 muscle contraction(GO:0006936)
0.1 3.9 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.1 8.4 GO:0030902 hindbrain development(GO:0030902)
0.1 5.6 GO:1902275 regulation of chromatin organization(GO:1902275)
0.1 5.4 GO:0001756 somitogenesis(GO:0001756)
0.1 0.6 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.1 1.6 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 1.5 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 1.4 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 2.2 GO:0008016 regulation of heart contraction(GO:0008016)
0.1 5.3 GO:1990778 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.1 3.4 GO:0007492 endoderm development(GO:0007492)
0.1 0.5 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.1 2.6 GO:0034968 histone lysine methylation(GO:0034968)
0.1 22.1 GO:0007420 brain development(GO:0007420)
0.1 2.1 GO:0009648 photoperiodism(GO:0009648)
0.1 0.2 GO:0016572 histone phosphorylation(GO:0016572)
0.1 1.4 GO:0010883 regulation of lipid storage(GO:0010883)
0.1 1.6 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.1 0.5 GO:0007584 response to nutrient(GO:0007584)
0.1 1.4 GO:0001649 osteoblast differentiation(GO:0001649)
0.1 0.6 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 2.0 GO:0005977 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.1 1.9 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.1 2.3 GO:0072666 protein targeting to vacuole(GO:0006623) establishment of protein localization to vacuole(GO:0072666)
0.0 3.0 GO:0048881 mechanosensory lateral line system development(GO:0048881)
0.0 9.1 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 6.9 GO:0007601 visual perception(GO:0007601)
0.0 0.4 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.9 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 3.2 GO:0045765 regulation of angiogenesis(GO:0045765)
0.0 0.7 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 1.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.8 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 2.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 2.7 GO:0006821 chloride transport(GO:0006821)
0.0 1.6 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 2.6 GO:0021782 glial cell development(GO:0021782)
0.0 3.6 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.7 GO:0061512 protein localization to cilium(GO:0061512)
0.0 1.0 GO:0021510 spinal cord development(GO:0021510)
0.0 3.8 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 1.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 4.9 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 1.8 GO:0048793 pronephros development(GO:0048793)
0.0 1.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 1.2 GO:0050769 positive regulation of neurogenesis(GO:0050769)
0.0 0.3 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0006032 chitin catabolic process(GO:0006032)
0.0 0.5 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 40.1 GO:0070062 extracellular exosome(GO:0070062)
4.6 31.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
3.0 12.0 GO:0032584 growth cone membrane(GO:0032584)
2.5 14.9 GO:0098837 postsynaptic recycling endosome(GO:0098837)
2.4 43.0 GO:0043209 myelin sheath(GO:0043209)
2.3 16.4 GO:0016012 sarcoglycan complex(GO:0016012)
2.2 6.7 GO:0031362 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
2.1 8.2 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
2.0 19.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
1.5 16.5 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
1.5 16.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
1.4 5.7 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
1.4 10.0 GO:0033010 paranodal junction(GO:0033010)
1.4 31.1 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
1.4 9.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
1.3 30.6 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
1.3 5.1 GO:0097524 sperm plasma membrane(GO:0097524)
1.1 13.5 GO:0044295 axonal growth cone(GO:0044295)
1.1 16.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
1.1 5.5 GO:0030314 junctional membrane complex(GO:0030314)
1.1 6.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.9 25.4 GO:0005844 polysome(GO:0005844)
0.8 3.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.7 2.9 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.7 9.2 GO:1990246 uniplex complex(GO:1990246)
0.7 9.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.7 8.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.6 4.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.6 36.2 GO:0031225 anchored component of membrane(GO:0031225)
0.5 5.4 GO:0000812 Swr1 complex(GO:0000812)
0.5 5.6 GO:0035101 FACT complex(GO:0035101)
0.5 9.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.5 9.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.4 25.6 GO:0016342 catenin complex(GO:0016342)
0.4 3.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 16.7 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.4 3.0 GO:0005614 interstitial matrix(GO:0005614)
0.4 9.0 GO:0071565 nBAF complex(GO:0071565)
0.3 5.5 GO:0005869 dynactin complex(GO:0005869)
0.3 6.6 GO:0031430 M band(GO:0031430)
0.3 1.9 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 6.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 35.1 GO:0043025 neuronal cell body(GO:0043025)
0.3 3.5 GO:0016580 Sin3 complex(GO:0016580)
0.3 3.2 GO:0034451 centriolar satellite(GO:0034451)
0.3 1.0 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.3 3.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 2.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 2.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 2.9 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 52.8 GO:0005911 cell-cell junction(GO:0005911)
0.2 4.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 18.2 GO:0030018 Z disc(GO:0030018)
0.2 11.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 1.8 GO:0089701 U2AF(GO:0089701)
0.2 1.4 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.2 1.5 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 11.7 GO:0031902 late endosome membrane(GO:0031902)
0.2 0.5 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 19.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 7.7 GO:0034704 calcium channel complex(GO:0034704)
0.1 2.3 GO:0031209 SCAR complex(GO:0031209)
0.1 3.9 GO:0000145 exocyst(GO:0000145)
0.1 2.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 3.1 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.9 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 1.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 5.7 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 3.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 6.2 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 5.1 GO:0030427 site of polarized growth(GO:0030427)
0.1 2.4 GO:0045180 basal cortex(GO:0045180)
0.1 2.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 27.9 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 2.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 17.1 GO:0036477 somatodendritic compartment(GO:0036477)
0.1 0.9 GO:0044545 NSL complex(GO:0044545)
0.1 4.6 GO:0005871 kinesin complex(GO:0005871)
0.1 7.6 GO:0035770 ribonucleoprotein granule(GO:0035770)
0.1 3.8 GO:0099572 postsynaptic specialization(GO:0099572)
0.0 19.8 GO:0043005 neuron projection(GO:0043005)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.8 GO:0005795 Golgi stack(GO:0005795)
0.0 2.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 11.0 GO:0005815 microtubule organizing center(GO:0005815)
0.0 2.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.5 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
9.1 36.4 GO:0044548 S100 protein binding(GO:0044548)
5.2 15.7 GO:0008179 adenylate cyclase binding(GO:0008179)
4.2 21.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
3.6 21.4 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
3.3 16.5 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
2.7 13.5 GO:0008046 axon guidance receptor activity(GO:0008046)
2.7 21.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
2.7 8.0 GO:0031716 calcitonin receptor binding(GO:0031716)
2.0 13.8 GO:0035173 histone kinase activity(GO:0035173)
1.9 40.9 GO:0046875 ephrin receptor binding(GO:0046875)
1.7 6.8 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
1.6 4.7 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
1.5 20.1 GO:0031628 opioid receptor binding(GO:0031628)
1.5 11.9 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.5 16.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
1.4 6.8 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
1.3 16.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
1.2 16.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
1.2 10.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
1.2 5.8 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
1.1 6.8 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
1.0 9.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.0 5.2 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.9 10.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.9 31.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.9 3.7 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.9 16.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.8 5.1 GO:0008126 acetylesterase activity(GO:0008126)
0.8 16.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.8 12.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.8 7.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.8 12.0 GO:0005504 fatty acid binding(GO:0005504)
0.8 3.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.7 2.9 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.7 41.5 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.7 12.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.7 11.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.7 17.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.7 3.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.6 7.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.6 18.9 GO:0030165 PDZ domain binding(GO:0030165)
0.6 3.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.6 2.3 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.5 7.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.5 3.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.5 17.2 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.5 6.8 GO:0034596 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.5 1.9 GO:0071253 connexin binding(GO:0071253)
0.5 4.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.5 1.4 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.5 1.9 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.4 10.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.4 5.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.4 35.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.4 4.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.4 3.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.4 9.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.4 2.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.4 3.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 4.3 GO:0005158 insulin receptor binding(GO:0005158)
0.3 5.7 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.3 2.9 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.3 6.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.3 0.9 GO:0000035 acyl binding(GO:0000035)
0.3 5.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 5.4 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.3 3.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 2.1 GO:0004849 uridine kinase activity(GO:0004849)
0.3 3.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 2.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 25.6 GO:0045296 cadherin binding(GO:0045296)
0.2 5.2 GO:0050811 GABA receptor binding(GO:0050811)
0.2 8.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 9.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 2.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 36.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.2 14.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 0.8 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.2 5.2 GO:0022829 wide pore channel activity(GO:0022829)
0.2 1.8 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.2 0.6 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.2 25.9 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.2 5.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 2.6 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.2 3.5 GO:0008301 DNA binding, bending(GO:0008301)
0.2 2.7 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.2 1.8 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.2 1.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 3.3 GO:0001671 ATPase activator activity(GO:0001671)
0.2 5.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.2 2.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 7.5 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 21.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 6.7 GO:0044325 ion channel binding(GO:0044325)
0.1 1.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 5.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 3.0 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.4 GO:0004046 aminoacylase activity(GO:0004046)
0.1 9.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.8 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 5.6 GO:0031491 nucleosome binding(GO:0031491)
0.1 14.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 1.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 5.0 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.1 1.7 GO:0016208 AMP binding(GO:0016208)
0.1 1.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 3.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 1.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 4.2 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.8 GO:0032977 membrane insertase activity(GO:0032977)
0.1 0.3 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 185.6 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 0.3 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 3.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 6.7 GO:0043130 ubiquitin binding(GO:0043130)
0.1 1.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.9 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 58.9 GO:0005509 calcium ion binding(GO:0005509)
0.1 2.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 23.9 GO:0051015 actin filament binding(GO:0051015)
0.1 1.3 GO:0031267 small GTPase binding(GO:0031267)
0.1 6.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 2.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.7 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 5.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.5 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 5.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.6 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.0 GO:0030552 cAMP binding(GO:0030552)
0.1 19.3 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.1 2.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 4.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.6 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 12.2 GO:0005543 phospholipid binding(GO:0005543)
0.0 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 4.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.7 GO:0002039 p53 binding(GO:0002039)
0.0 1.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 1.0 GO:0043022 ribosome binding(GO:0043022)
0.0 5.5 GO:0019901 protein kinase binding(GO:0019901)
0.0 2.9 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 2.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 2.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 1.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.0 GO:0005267 potassium channel activity(GO:0005267)
0.0 4.5 GO:0015631 tubulin binding(GO:0015631)
0.0 0.6 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 28.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.6 14.9 PID RAS PATHWAY Regulation of Ras family activation
0.6 14.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.5 6.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.5 12.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 6.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.4 5.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.4 12.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.4 7.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.4 7.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3 5.7 PID RHOA PATHWAY RhoA signaling pathway
0.2 1.6 PID IGF1 PATHWAY IGF1 pathway
0.2 2.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 5.4 PID MYC PATHWAY C-MYC pathway
0.2 3.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 2.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 3.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 22.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 5.7 PID AP1 PATHWAY AP-1 transcription factor network
0.1 2.9 ST ADRENERGIC Adrenergic Pathway
0.1 2.5 PID ATM PATHWAY ATM pathway
0.1 3.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 3.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 3.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 36.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
1.1 26.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
1.1 16.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.8 18.8 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.7 6.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.5 5.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.5 5.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.4 9.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.4 5.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.4 6.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.3 3.0 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.3 8.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.3 12.8 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.3 3.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 7.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 3.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 1.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 8.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 6.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 5.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.2 4.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 10.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.2 3.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 5.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 3.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 4.7 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 1.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 12.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.8 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 1.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 5.2 REACTOME NEURONAL SYSTEM Genes involved in Neuronal System
0.1 3.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors