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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for pgr

Z-value: 0.71

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Transcription factors associated with pgr

Gene Symbol Gene ID Gene Info
pgr
ENSDARG00000035966 progesterone receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pgrdr11_v1_chr18_+_41820039_418200390.197.0e-02Click!

Activity profile of pgr motif

Sorted Z-values of pgr motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_7538909 5.04 ENSDART00000148276
mylz3
myosin, light polypeptide 3, skeletal muscle
chr22_-_278328 4.00 ENSDART00000098072
myhz1.1
myosin, heavy polypeptide 1.1, skeletal muscle
chr9_-_22831836 3.95 ENSDART00000142585
neb
nebulin
chr11_+_21076872 3.88 ENSDART00000155521
prelp
proline/arginine-rich end leucine-rich repeat protein
chr6_-_39764995 3.49 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr8_-_18535822 3.34 ENSDART00000100558
nexn
nexilin (F actin binding protein)
chr4_-_16406737 3.12 ENSDART00000013085
dcn
decorin
chr18_+_9171778 3.02 ENSDART00000101192
sema3d
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr16_+_47308856 3.01 ENSDART00000170103
col28a1b
collagen, type XXVIII, alpha 1b
chr20_-_29483514 2.91 ENSDART00000062370
actc1a
actin, alpha, cardiac muscle 1a
chr6_-_39765546 2.86 ENSDART00000185767
pfkmb
phosphofructokinase, muscle b
chr7_+_39389273 2.79 ENSDART00000191298
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr6_-_20707846 2.78 ENSDART00000169836
col18a1b
collagen type XVIII alpha 1 chain b
chr8_+_11687254 2.65 ENSDART00000042040
atp2a2a
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr19_-_47555956 2.65 ENSDART00000114549
actc1a
actin, alpha, cardiac muscle 1a
chr15_+_32710300 2.57 ENSDART00000167857
postnb
periostin, osteoblast specific factor b
chr18_-_6634424 2.55 ENSDART00000062423
ENSDART00000179955
tnni1c
troponin I, skeletal, slow c
chr20_+_572037 2.51 ENSDART00000028062
ENSDART00000152736
ENSDART00000031759
ENSDART00000162198
smyd2b
SET and MYND domain containing 2b
chr14_-_25949713 2.48 ENSDART00000181455
sparc
secreted protein, acidic, cysteine-rich (osteonectin)
chr21_-_22737228 2.47 ENSDART00000151366
fbxo40.2
F-box protein 40, tandem duplicate 2
chr21_+_10866421 2.41 ENSDART00000137858
alpk2
alpha-kinase 2
chr24_+_3307857 2.39 ENSDART00000106527
gyg1b
glycogenin 1b
chr15_+_38046435 2.38 ENSDART00000156481
si:ch73-380l3.4
si:ch73-380l3.4
chr9_+_24095677 2.30 ENSDART00000150443
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr9_-_33107237 2.29 ENSDART00000013918
casq2
calsequestrin 2
chr5_-_32308526 2.23 ENSDART00000193758
myhz1.1
myosin, heavy polypeptide 1.1, skeletal muscle
chr16_-_6821927 2.21 ENSDART00000149070
ENSDART00000149570
mbpb
myelin basic protein b
chr8_+_11687586 2.12 ENSDART00000146241
atp2a2a
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr25_+_31277415 2.12 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr20_-_26846028 2.06 ENSDART00000136687
mylk4b
myosin light chain kinase family, member 4b
chr3_+_49397115 2.06 ENSDART00000176042
tecra
trans-2,3-enoyl-CoA reductase a
chr22_-_15602760 2.03 ENSDART00000009054
tpm4a
tropomyosin 4a
chr18_+_5547185 2.02 ENSDART00000193977
nnt2
nicotinamide nucleotide transhydrogenase 2
chr9_-_42696408 1.98 ENSDART00000144744
col5a2a
collagen, type V, alpha 2a
chr18_+_16744307 1.96 ENSDART00000179872
ENSDART00000133490
lyve1b
lymphatic vessel endothelial hyaluronic receptor 1b
chr2_-_29485408 1.94 ENSDART00000013411
cahz
carbonic anhydrase
chr9_+_44832032 1.92 ENSDART00000002633
frzb
frizzled related protein
chr22_+_18477934 1.92 ENSDART00000132684
cilp2
cartilage intermediate layer protein 2
chr8_-_11229523 1.89 ENSDART00000002164
unc45b
unc-45 myosin chaperone B
chr15_+_32710094 1.81 ENSDART00000159592
postnb
periostin, osteoblast specific factor b
chr20_-_26420939 1.76 ENSDART00000110883
akap12b
A kinase (PRKA) anchor protein 12b
chr14_-_2602445 1.75 ENSDART00000166910
etf1a
eukaryotic translation termination factor 1a
chr6_+_27339962 1.74 ENSDART00000193726
klhl30
kelch-like family member 30
chr16_-_11766265 1.73 ENSDART00000141547
zgc:158701
zgc:158701
chr6_+_23887314 1.73 ENSDART00000163188
znf648
zinc finger protein 648
chr18_+_29145681 1.73 ENSDART00000089031
ENSDART00000193336
ppfibp2a
PTPRF interacting protein, binding protein 2a (liprin beta 2)
chr20_-_26421112 1.63 ENSDART00000183767
ENSDART00000182330
akap12b
A kinase (PRKA) anchor protein 12b
chr21_-_25601648 1.63 ENSDART00000042578
efemp2b
EGF containing fibulin extracellular matrix protein 2b
chr10_+_8968203 1.62 ENSDART00000110443
ENSDART00000080772
fstb
follistatin b
chr3_+_16449490 1.59 ENSDART00000141467
kcnj12b
potassium inwardly-rectifying channel, subfamily J, member 12b
chr16_+_30438041 1.59 ENSDART00000137977
pear1
platelet endothelial aggregation receptor 1
chr5_-_41307550 1.59 ENSDART00000143446
npr3
natriuretic peptide receptor 3
chr2_+_45159855 1.57 ENSDART00000056333
CU929150.1

chr8_+_44549290 1.57 ENSDART00000160801
si:dkey-220o5.5
si:dkey-220o5.5
chr24_-_27473771 1.51 ENSDART00000139874
cxl34b.11
CX chemokine ligand 34b, duplicate 11
chr15_+_36105581 1.50 ENSDART00000184099
col4a3
collagen, type IV, alpha 3
chr6_+_41096058 1.49 ENSDART00000028373
fkbp5
FK506 binding protein 5
chr1_-_10914523 1.49 ENSDART00000007013
dmd
dystrophin
chr21_-_26089964 1.45 ENSDART00000027848
tlcd1
TLC domain containing 1
chr18_-_39200557 1.45 ENSDART00000132367
ENSDART00000183672
si:ch211-235f12.2
mapk6
si:ch211-235f12.2
mitogen-activated protein kinase 6
chr2_+_54827391 1.43 ENSDART00000167269
twsg1a
twisted gastrulation BMP signaling modulator 1a
chr22_-_15602593 1.42 ENSDART00000036075
tpm4a
tropomyosin 4a
chr1_+_31054915 1.41 ENSDART00000148968
itga6b
integrin, alpha 6b
chr9_+_31752628 1.36 ENSDART00000060054
itgbl1
integrin, beta-like 1
chr9_-_34944604 1.35 ENSDART00000140563
ENSDART00000136812
dcun1d2a
DCN1, defective in cullin neddylation 1, domain containing 2a
chr6_-_54815886 1.35 ENSDART00000180793
ENSDART00000007498
tnni1b
troponin I type 1b (skeletal, slow)
chr13_-_31622195 1.33 ENSDART00000057432
six1a
SIX homeobox 1a
chr6_-_40429411 1.33 ENSDART00000156005
ENSDART00000156357
si:dkey-28n18.9
si:dkey-28n18.9
chr13_-_37619159 1.30 ENSDART00000186348
zgc:152791
zgc:152791
chr7_-_2163361 1.29 ENSDART00000173654
si:cabz01007812.1
si:cabz01007812.1
chr4_+_77810982 1.29 ENSDART00000184697
si:dkey-238k10.3
si:dkey-238k10.3
chr12_-_44122412 1.28 ENSDART00000169094
si:ch73-329n5.3
si:ch73-329n5.3
chr21_+_11244068 1.26 ENSDART00000163432
arid6
AT-rich interaction domain 6
chr9_-_46842179 1.25 ENSDART00000054137
igfbp5b
insulin-like growth factor binding protein 5b
chr2_-_37893910 1.23 ENSDART00000143027
hbl2
hexose-binding lectin 2
chr24_-_38816725 1.17 ENSDART00000063231
nog2
noggin 2
chr20_-_49657134 1.17 ENSDART00000151248
col12a1b
collagen, type XII, alpha 1b
chr12_+_23875318 1.17 ENSDART00000152869
svila
supervillin a
chr3_-_28048475 1.16 ENSDART00000150888
rbfox1
RNA binding fox-1 homolog 1
chr5_+_39667272 1.13 ENSDART00000085388
bmp3
bone morphogenetic protein 3
chr2_-_31018062 1.10 ENSDART00000140841
ENSDART00000087026
emilin2a
elastin microfibril interfacer 2a
chr18_-_41650648 1.10 ENSDART00000024087
fzd9b
frizzled class receptor 9b
chr6_+_41099787 1.07 ENSDART00000186884
fkbp5
FK506 binding protein 5
chr2_-_37858723 1.02 ENSDART00000145711
si:ch211-284o19.8
si:ch211-284o19.8
chr19_-_32641725 1.01 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr21_+_21621042 1.01 ENSDART00000134907
tgfb1b
transforming growth factor, beta 1b
chr16_-_9425451 0.98 ENSDART00000149163
ccr8.1
chemokine (C-C motif) receptor 8.1
chr1_+_45121393 0.98 ENSDART00000142702
muc13a
mucin 13a, cell surface associated
chr1_-_59095035 0.96 ENSDART00000130791
MFAP4 (1 of many)
wu:fj11g02
chr17_-_20849879 0.96 ENSDART00000088100
ENSDART00000149630
ank3b
ankyrin 3b
chr1_+_58393630 0.95 ENSDART00000168762
si:ch73-236c18.2
si:ch73-236c18.2
chr16_-_35975254 0.95 ENSDART00000167537
eva1ba
eva-1 homolog Ba (C. elegans)
chr1_+_58456494 0.93 ENSDART00000164130
si:ch73-236c18.5
si:ch73-236c18.5
chr15_-_35406564 0.93 ENSDART00000086051
mecom
MDS1 and EVI1 complex locus
chr23_-_45501177 0.93 ENSDART00000150103
col24a1
collagen type XXIV alpha 1
chr7_-_3748702 0.93 ENSDART00000134839
si:ch211-282j17.10
si:ch211-282j17.10
chr2_-_37896965 0.92 ENSDART00000129852
hbl1
hexose-binding lectin 1
chr24_-_32025637 0.92 ENSDART00000180448
ENSDART00000159034
rsu1
Ras suppressor protein 1
chr6_+_60112200 0.92 ENSDART00000008243
prelid3b
PRELI domain containing 3
chr14_+_22132896 0.92 ENSDART00000138274
ccng1
cyclin G1
chr8_-_36475328 0.91 ENSDART00000048448
si:busm1-266f07.2
si:busm1-266f07.2
chr15_-_23699737 0.91 ENSDART00000078311
zgc:154093
zgc:154093
chr6_-_48082525 0.91 ENSDART00000192049
slc2a1b
solute carrier family 2 (facilitated glucose transporter), member 1b
chr24_-_33756003 0.90 ENSDART00000079283
tmeff1b
transmembrane protein with EGF-like and two follistatin-like domains 1b
chr19_-_27542433 0.90 ENSDART00000136414
si:ch211-152p11.4
si:ch211-152p11.4
chr20_-_35706379 0.90 ENSDART00000152847
si:dkey-30j22.1
si:dkey-30j22.1
chr22_-_4778018 0.89 ENSDART00000143968
si:ch73-256j6.5
si:ch73-256j6.5
chr15_+_37950556 0.89 ENSDART00000153947
si:dkey-238d18.12
si:dkey-238d18.12
chr10_+_31938796 0.89 ENSDART00000182579
lhfpl6
LHFPL tetraspan subfamily member 6
chr9_-_8454060 0.88 ENSDART00000110158
irs2b
insulin receptor substrate 2b
chr4_+_10616626 0.87 ENSDART00000067251
ENSDART00000143690
cped1
cadherin-like and PC-esterase domain containing 1
chr5_+_51102010 0.87 ENSDART00000110377
zgc:194398
zgc:194398
chr15_-_41720173 0.86 ENSDART00000155585
ENSDART00000075909
ftr76
finTRIM family, member 76
chr8_-_19975087 0.86 ENSDART00000182220
lpxn
leupaxin
chr6_+_12462079 0.86 ENSDART00000192029
ENSDART00000065385
nr4a2b
nuclear receptor subfamily 4, group A, member 2b
chr1_-_5746030 0.85 ENSDART00000150863
nrp2a
neuropilin 2a
chr22_-_968484 0.85 ENSDART00000105895
cacna1sa
calcium channel, voltage-dependent, L type, alpha 1S subunit, a
chr21_+_25187210 0.85 ENSDART00000101147
ENSDART00000167528
si:dkey-183i3.5
si:dkey-183i3.5
chr12_-_44180132 0.85 ENSDART00000165998
si:ch73-329n5.1
si:ch73-329n5.1
chr3_-_4253214 0.84 ENSDART00000155807
si:dkey-175d9.2
si:dkey-175d9.2
chr3_-_26109322 0.84 ENSDART00000113780
zgc:162612
zgc:162612
chr12_-_44148073 0.84 ENSDART00000166273
si:ch73-329n5.1
si:ch73-329n5.1
chr7_+_35245607 0.84 ENSDART00000193422
ENSDART00000173888
amfrb
autocrine motility factor receptor b
chr3_-_8130926 0.83 ENSDART00000189495
si:ch211-51i16.1
si:ch211-51i16.1
chr23_+_21663631 0.82 ENSDART00000066125
dhrs3a
dehydrogenase/reductase (SDR family) member 3a
chr10_+_26669177 0.82 ENSDART00000143402
si:ch73-52f15.5
si:ch73-52f15.5
chr13_-_50309969 0.81 ENSDART00000191597
CU928131.1

chr3_-_58650057 0.81 ENSDART00000057640
dhrs7ca
dehydrogenase/reductase (SDR family) member 7Ca
chr4_+_8532580 0.80 ENSDART00000162065
wnt5b
wingless-type MMTV integration site family, member 5b
chr6_+_9155271 0.80 ENSDART00000168727
zgc:64065
zgc:64065
chr1_-_58868306 0.80 ENSDART00000166615
dnm2b
dynamin 2b
chr3_+_8224622 0.77 ENSDART00000138670
si:ch73-379f5.5
si:ch73-379f5.5
chr21_-_9466201 0.76 ENSDART00000167211
ptpn13
protein tyrosine phosphatase, non-receptor type 13
chr13_-_36391496 0.75 ENSDART00000100217
ENSDART00000140243
actn1
actinin, alpha 1
chr13_+_18523661 0.74 ENSDART00000034852
tlr4bb
toll-like receptor 4b, duplicate b
chr2_-_55337585 0.74 ENSDART00000177924
tpm4b
tropomyosin 4b
chr25_+_15933411 0.74 ENSDART00000191581
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr12_-_1951233 0.74 ENSDART00000005676
ENSDART00000127937
sox9a
SRY (sex determining region Y)-box 9a
chr7_+_4971938 0.73 ENSDART00000172889
ENSDART00000145389
si:dkey-81n2.2
si:dkey-81n2.2
chr22_+_1899142 0.73 ENSDART00000167369
znf1158
zinc finger protein 1158
chr1_+_58194268 0.72 ENSDART00000146252
si:dkey-222h21.11
si:dkey-222h21.11
chr15_-_43270889 0.72 ENSDART00000166805
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr24_+_23742690 0.72 ENSDART00000130162
TCF24
transcription factor 24
chr12_-_46176115 0.70 ENSDART00000152848
si:ch211-226h7.8
si:ch211-226h7.8
chr5_-_37116265 0.70 ENSDART00000057613
il13ra2
interleukin 13 receptor, alpha 2
chr14_+_21934331 0.70 ENSDART00000123225
zgc:113229
zgc:113229
chr7_-_27033080 0.69 ENSDART00000173516
nucb2a
nucleobindin 2a
chr15_-_163586 0.69 ENSDART00000163597
SEPT4
septin-4
chr15_-_37799496 0.69 ENSDART00000156874
si:dkey-42l23.2
si:dkey-42l23.2
chr9_+_19489514 0.68 ENSDART00000152032
ENSDART00000114256
ENSDART00000190572
ENSDART00000147571
ENSDART00000151918
ENSDART00000152034
si:ch211-140m22.7
si:ch211-140m22.7
chr17_+_27162367 0.68 ENSDART00000193345
rps6ka1
ribosomal protein S6 kinase a, polypeptide 1
chr8_+_39570615 0.67 ENSDART00000142557
lzts1
leucine zipper, putative tumor suppressor 1
chr10_+_6121558 0.67 ENSDART00000166799
ENSDART00000157947
tln1
talin 1
chr2_-_32352946 0.66 ENSDART00000144870
ENSDART00000077151
asap1a
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a
chr2_-_50053006 0.66 ENSDART00000083654
si:ch211-106n13.3
si:ch211-106n13.3
chr17_+_20504196 0.65 ENSDART00000190539
neurl1ab
neuralized E3 ubiquitin protein ligase 1Ab
chr21_-_22317920 0.65 ENSDART00000191083
ENSDART00000108701
gdpd4b
glycerophosphodiester phosphodiesterase domain containing 4b
chr9_-_43001898 0.64 ENSDART00000138515
ttn.2
titin, tandem duplicate 2
chr8_-_43834442 0.63 ENSDART00000191927
adgrd1
adhesion G protein-coupled receptor D1
chr1_+_57757456 0.63 ENSDART00000152650
si:dkey-1c7.1
si:dkey-1c7.1
chr14_+_6159162 0.62 ENSDART00000128638
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr4_+_42419522 0.62 ENSDART00000135737
si:dkey-16p6.1
si:dkey-16p6.1
chr15_+_43093044 0.62 ENSDART00000141125
kcne4
potassium voltage-gated channel, Isk-related family, member 4
chr5_-_66768121 0.61 ENSDART00000141095
FERMT3 (1 of many)
im:7154036
chr18_-_20608300 0.59 ENSDART00000140632
bcl2l13
BCL2 like 13
chr4_+_33012407 0.59 ENSDART00000151873
si:dkey-26h11.2
si:dkey-26h11.2
chr18_+_9382847 0.59 ENSDART00000061886
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr3_-_11040575 0.59 ENSDART00000159802
CR382337.2

chr15_-_21678634 0.59 ENSDART00000061139
bco2b
beta-carotene oxygenase 2b
chr12_-_5188413 0.59 ENSDART00000161988
fra10ac1
FRA10A associated CGG repeat 1
chr7_+_4642009 0.58 ENSDART00000134368
ENSDART00000143622
si:dkey-83f18.5
si:dkey-83f18.5
chr7_+_4671241 0.58 ENSDART00000147528
si:ch211-225k7.6
si:ch211-225k7.6
chr17_-_7501916 0.58 ENSDART00000141987
si:ch211-278p9.3
si:ch211-278p9.3
chr15_-_41714329 0.58 ENSDART00000154113
CR853294.1

chr19_+_19762183 0.58 ENSDART00000163611
ENSDART00000187604
hoxa3a
homeobox A3a
chr3_+_20156956 0.58 ENSDART00000125281
ngfra
nerve growth factor receptor a (TNFR superfamily, member 16)
chr11_+_25388747 0.57 ENSDART00000103649
ENSDART00000154935
si:dkeyp-97e7.9
si:dkeyp-97e7.9
chr12_-_4408828 0.57 ENSDART00000152447
si:ch211-173d10.1
si:ch211-173d10.1
chr3_+_23731109 0.57 ENSDART00000131410
hoxb3a
homeobox B3a
chr22_+_1837448 0.57 ENSDART00000160015
znf1183
zinc finger protein 1183
chr5_-_52216170 0.56 ENSDART00000158542
ENSDART00000192981
lnpep
leucyl/cystinyl aminopeptidase
chr23_+_36095260 0.55 ENSDART00000127384
hoxc9a
homeobox C9a
chr15_-_41762530 0.55 ENSDART00000187125
ENSDART00000154971
ftr91
finTRIM family, member 91
chr7_+_4671483 0.55 ENSDART00000111390
si:ch211-225k7.6
si:ch211-225k7.6
chr12_-_16380242 0.55 ENSDART00000168105
hectd2
HECT domain containing 2
chr7_+_4987530 0.54 ENSDART00000132983
ENSDART00000137067
si:dkey-81n2.1
si:dkey-81n2.1
chr1_+_58282449 0.54 ENSDART00000131475
si:dkey-222h21.7
si:dkey-222h21.7
chr9_+_30211038 0.54 ENSDART00000190847
senp7a
SUMO1/sentrin specific peptidase 7a
chr6_-_54290227 0.53 ENSDART00000050483
SPDEF
SAM pointed domain containing ETS transcription factor
chr7_-_33868903 0.53 ENSDART00000173500
ENSDART00000178746
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr9_+_23770666 0.53 ENSDART00000182493
si:ch211-219a4.3
si:ch211-219a4.3
chr15_+_37986069 0.52 ENSDART00000156984
si:dkey-238d18.8
si:dkey-238d18.8
chr1_+_54871725 0.52 ENSDART00000193654
si:ch211-196h16.5
si:ch211-196h16.5
chr6_-_29612269 0.51 ENSDART00000104293
pex5la
peroxisomal biogenesis factor 5-like a
chr7_+_52761841 0.51 ENSDART00000111444
ppip5k1a
diphosphoinositol pentakisphosphate kinase 1a
chr4_-_16333944 0.51 ENSDART00000079523
epyc
epiphycan
chr17_-_7484354 0.51 ENSDART00000144941
si:ch211-278p9.2
si:ch211-278p9.2
chr5_+_22970617 0.51 ENSDART00000192859
hmgn7
high mobility group nucleosomal binding domain 7
chr18_+_27101096 0.51 ENSDART00000171128
ENSDART00000086094
plekha7a
pleckstrin homology domain containing, family A member 7a
chr21_+_14511685 0.51 ENSDART00000102099
CR392036.1

Network of associatons between targets according to the STRING database.

First level regulatory network of pgr

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.9 5.6 GO:0003272 endocardial cushion formation(GO:0003272)
0.7 3.9 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.6 3.0 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508)
0.6 6.4 GO:0061620 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.6 2.3 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.5 2.0 GO:0006740 NADPH regeneration(GO:0006740)
0.5 1.9 GO:0015670 carbon dioxide transport(GO:0015670)
0.5 3.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.4 1.9 GO:0035988 chondrocyte proliferation(GO:0035988)
0.4 1.1 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.4 1.5 GO:0055091 phospholipid homeostasis(GO:0055091)
0.4 6.4 GO:0016203 muscle attachment(GO:0016203)
0.3 1.7 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.3 1.3 GO:0014856 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.3 2.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 1.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.2 0.9 GO:0001782 B cell homeostasis(GO:0001782) positive regulation of B cell proliferation(GO:0030890)
0.2 6.0 GO:0007379 somite specification(GO:0001757) segment specification(GO:0007379)
0.2 0.6 GO:0071435 potassium ion export(GO:0071435) potassium ion export across plasma membrane(GO:0097623)
0.2 12.3 GO:0060048 cardiac muscle contraction(GO:0060048)
0.2 1.0 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.2 0.5 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 0.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 1.8 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.2 0.8 GO:1904105 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.1 1.6 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.6 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.4 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.1 0.4 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.4 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.5 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 1.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 3.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.6 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.1 0.9 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.9 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 1.4 GO:0045116 protein neddylation(GO:0045116)
0.1 0.4 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.1 3.4 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.6 GO:0060017 parathyroid gland development(GO:0060017)
0.1 1.6 GO:0014855 striated muscle cell proliferation(GO:0014855)
0.1 1.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.0 GO:0048769 sarcomerogenesis(GO:0048769)
0.1 2.4 GO:0055013 cardiac muscle cell development(GO:0055013)
0.1 0.7 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 0.5 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 2.3 GO:0001649 osteoblast differentiation(GO:0001649)
0.1 0.6 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.3 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 2.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 2.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 4.2 GO:0008016 regulation of heart contraction(GO:0008016)
0.1 0.8 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.3 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.2 GO:0021576 hindbrain formation(GO:0021576)
0.1 0.2 GO:0061033 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 1.8 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 0.4 GO:0032963 collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.1 1.2 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.1 0.2 GO:0061195 tongue development(GO:0043586) tongue morphogenesis(GO:0043587) taste bud development(GO:0061193) taste bud morphogenesis(GO:0061194) taste bud formation(GO:0061195) sympathetic ganglion development(GO:0061549)
0.1 0.4 GO:0030728 ovulation(GO:0030728)
0.1 0.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.5 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.7 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.8 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.8 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.0 0.4 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.0 0.1 GO:0060945 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.0 0.9 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 0.4 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.4 GO:0032925 regulation of activin receptor signaling pathway(GO:0032925) regulation of nodal signaling pathway(GO:1900107)
0.0 0.1 GO:0060958 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.0 9.9 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.4 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.6 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.3 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0 2.5 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.2 GO:0021982 pineal gland development(GO:0021982)
0.0 0.5 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.2 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.3 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.1 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.4 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 1.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.9 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.2 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.2 GO:0042554 superoxide anion generation(GO:0042554)
0.0 1.0 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.5 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.4 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 1.4 GO:0060047 heart contraction(GO:0060047)
0.0 1.1 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 1.9 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.7 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.7 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.4 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 1.7 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.9 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.2 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 1.3 GO:0030510 regulation of BMP signaling pathway(GO:0030510)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.9 GO:0043542 endothelial cell migration(GO:0043542)
0.0 0.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 1.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.0 GO:0044321 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:0002224 toll-like receptor signaling pathway(GO:0002224)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.5 2.0 GO:0005588 collagen type V trimer(GO:0005588)
0.5 1.4 GO:0005592 collagen type XI trimer(GO:0005592)
0.3 1.7 GO:0018444 translation release factor complex(GO:0018444)
0.3 5.6 GO:0005869 dynactin complex(GO:0005869)
0.3 2.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 8.8 GO:0005861 troponin complex(GO:0005861)
0.2 4.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 0.5 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 2.2 GO:0043209 myelin sheath(GO:0043209)
0.1 10.5 GO:0005581 collagen trimer(GO:0005581)
0.1 10.4 GO:0030018 Z disc(GO:0030018)
0.1 0.5 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 2.8 GO:0008305 integrin complex(GO:0008305)
0.1 1.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.3 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 6.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.4 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.8 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 4.2 GO:0005884 actin filament(GO:0005884)
0.0 2.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.5 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 2.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.4 GO:0000786 nucleosome(GO:0000786)
0.0 3.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.5 GO:0045178 basal part of cell(GO:0045178) basal cortex(GO:0045180)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.0 GO:0005925 focal adhesion(GO:0005925)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.7 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 18.8 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.9 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.2 GO:0099572 postsynaptic specialization(GO:0099572)
0.0 0.7 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.6 1.7 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.6 6.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.5 2.0 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.3 4.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.3 1.6 GO:0042169 SH2 domain binding(GO:0042169)
0.2 3.6 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.2 1.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 1.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 2.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 5.6 GO:0005518 collagen binding(GO:0005518)
0.1 2.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 2.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.9 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.5 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 15.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.2 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 1.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.3 GO:0046978 TAP1 binding(GO:0046978)
0.1 3.4 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 3.3 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.4 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1 1.6 GO:0030546 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.1 0.3 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.1 3.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.7 GO:0043121 neurotrophin binding(GO:0043121)
0.1 1.6 GO:0048185 activin binding(GO:0048185)
0.1 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 2.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.6 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 2.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 16.4 GO:0051015 actin filament binding(GO:0051015)
0.0 1.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.4 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 1.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 4.6 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 1.0 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.9 GO:0019957 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.4 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.7 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.7 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.7 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 1.1 GO:0005125 cytokine activity(GO:0005125)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 2.0 GO:0046982 protein heterodimerization activity(GO:0046982)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.7 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 2.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 3.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 2.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 4.7 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 5.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 3.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 5.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 0.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 2.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 2.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR