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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for pou1f1

Z-value: 0.63

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Transcription factors associated with pou1f1

Gene Symbol Gene ID Gene Info
pou1f1
ENSDARG00000058924 POU class 1 homeobox 1
pou1f1
ENSDARG00000110816 POU class 1 homeobox 1
pou1f1
ENSDARG00000115109 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou1f1dr11_v1_chr9_-_19161982_19161982-0.103.2e-01Click!

Activity profile of pou1f1 motif

Sorted Z-values of pou1f1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_17712393 17.90 ENSDART00000143534
ENSDART00000010144
pvalb2
parvalbumin 2
chr13_+_24279021 7.61 ENSDART00000058629
acta1b
actin, alpha 1b, skeletal muscle
chr3_+_26145013 6.17 ENSDART00000162546
ENSDART00000129561
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr19_+_46158078 5.96 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr7_+_59020972 5.57 ENSDART00000157873
hacd1
3-hydroxyacyl-CoA dehydratase 1
chr5_-_44829719 5.20 ENSDART00000019104
fbp2
fructose-1,6-bisphosphatase 2
chr25_+_14087045 4.77 ENSDART00000155770
actc1c
actin, alpha, cardiac muscle 1c
chr13_+_9432501 4.69 ENSDART00000058064
zgc:123321
zgc:123321
chr23_+_26026383 4.31 ENSDART00000141553
pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr22_-_31060579 3.55 ENSDART00000182376
cand2
cullin-associated and neddylation-dissociated 2 (putative)
chr15_-_20939579 3.38 ENSDART00000152371
usp2a
ubiquitin specific peptidase 2a
chr1_+_5402476 3.03 ENSDART00000040204
tuba8l2
tubulin, alpha 8 like 2
chr6_+_40714811 3.03 ENSDART00000153868
ccdc36
coiled-coil domain containing 36
chr3_-_59297532 2.89 ENSDART00000187991
CABZ01053748.1

chr5_-_71705191 2.84 ENSDART00000187767
ak1
adenylate kinase 1
chr5_+_71802014 2.79 ENSDART00000124939
ENSDART00000097164
LHX3
LIM homeobox 3
chr22_-_24818066 2.69 ENSDART00000143443
vtg6
vitellogenin 6
chr20_-_40755614 2.63 ENSDART00000061247
cx32.3
connexin 32.3
chr16_+_12836143 2.58 ENSDART00000067741
cacng6b
calcium channel, voltage-dependent, gamma subunit 6b
chr5_+_33498253 2.42 ENSDART00000140993
ms4a17c.2
membrane-spanning 4-domains, subfamily A, member 17c.2
chr9_-_22099536 2.39 ENSDART00000101923
CR391987.1

chr4_-_948776 2.32 ENSDART00000023483
sim1b
single-minded family bHLH transcription factor 1b
chr5_-_1203455 2.31 ENSDART00000172177
surf4
surfeit gene 4
chr13_-_31622195 2.30 ENSDART00000057432
six1a
SIX homeobox 1a
chr8_-_53044300 2.22 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr16_+_51326237 2.09 ENSDART00000168525
CU469384.1

chr4_+_22480169 2.07 ENSDART00000146272
ENSDART00000066904
ndufb2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr13_-_12602920 2.06 ENSDART00000102311
lrit3b
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr22_-_24738188 2.00 ENSDART00000050238
vtg1
vitellogenin 1
chr2_+_20496223 1.99 ENSDART00000157931
agla
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase a
chr5_-_41494831 1.90 ENSDART00000051081
eef2l2
eukaryotic translation elongation factor 2, like 2
chr18_+_39487486 1.83 ENSDART00000126978
acadl
acyl-CoA dehydrogenase long chain
chr19_+_31873308 1.66 ENSDART00000146560
ENSDART00000133045
si:dkeyp-34f6.4
si:dkeyp-34f6.4
chr9_+_54290896 1.64 ENSDART00000149175
pou4f3
POU class 4 homeobox 3
chr23_-_18707418 1.61 ENSDART00000144668
ENSDART00000141205
ENSDART00000016765
zgc:103759
zgc:103759
chr9_+_48761455 1.60 ENSDART00000139631
abcb11a
ATP-binding cassette, sub-family B (MDR/TAP), member 11a
chr17_-_30702411 1.59 ENSDART00000114358
zgc:194392
zgc:194392
chr2_+_36004381 1.58 ENSDART00000098706
lamc2
laminin, gamma 2
chr16_-_38118003 1.52 ENSDART00000058667
si:dkey-23o4.6
si:dkey-23o4.6
chr19_+_43780970 1.50 ENSDART00000063870
rpl11
ribosomal protein L11
chr7_+_21272833 1.48 ENSDART00000052942
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr2_+_20605925 1.48 ENSDART00000191510
olfml2bb
olfactomedin-like 2Bb
chr2_+_49799470 1.45 ENSDART00000146325
si:ch211-190k17.19
si:ch211-190k17.19
chr10_+_21867307 1.44 ENSDART00000126629
cbln17
cerebellin 17
chr17_+_30591287 1.43 ENSDART00000154243
si:dkey-190l8.2
si:dkey-190l8.2
chr8_+_17987215 1.42 ENSDART00000113605
lrriq3
leucine-rich repeats and IQ motif containing 3
chr7_+_51774502 1.42 ENSDART00000007767
got2b
glutamic-oxaloacetic transaminase 2b, mitochondrial
chr7_-_7692723 1.41 ENSDART00000183352
aadat
aminoadipate aminotransferase
chr22_+_1556948 1.41 ENSDART00000159050
si:ch211-255f4.8
si:ch211-255f4.8
chr23_+_32101202 1.39 ENSDART00000000992
zgc:56699
zgc:56699
chr18_+_27821856 1.39 ENSDART00000131712
si:ch211-222m18.4
si:ch211-222m18.4
chr23_+_4709607 1.36 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
raf1a
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr14_+_36521005 1.35 ENSDART00000192286
TENM3
si:dkey-237h12.3
chr5_+_2815021 1.34 ENSDART00000020472
hpda
4-hydroxyphenylpyruvate dioxygenase a
chr9_+_28598577 1.34 ENSDART00000142623
ENSDART00000135947
si:ch73-7i4.1
si:ch73-7i4.1
chr7_+_4694762 1.34 ENSDART00000132862
si:ch211-225k7.3
si:ch211-225k7.3
chr25_+_22320738 1.31 ENSDART00000073566
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr23_-_41965557 1.31 ENSDART00000144183
slc1a7b
solute carrier family 1 (glutamate transporter), member 7b
chr17_+_15559046 1.30 ENSDART00000187126
bach2a
BTB and CNC homology 1, basic leucine zipper transcription factor 2a
chr13_-_39736938 1.29 ENSDART00000141645
zgc:171482
zgc:171482
chr16_-_25608453 1.29 ENSDART00000140140
zgc:110410
zgc:110410
chr25_+_5972690 1.28 ENSDART00000067517
si:ch211-11i22.4
si:ch211-11i22.4
chr13_-_9886579 1.27 ENSDART00000101926
si:ch211-117n7.7
si:ch211-117n7.7
chr15_+_9327252 1.26 ENSDART00000144381
sgcg
sarcoglycan, gamma
chr8_+_17987778 1.26 ENSDART00000133429
lrriq3
leucine-rich repeats and IQ motif containing 3
chr23_-_19140781 1.25 ENSDART00000143580
si:ch73-381f5.2
si:ch73-381f5.2
chr7_+_49800478 1.25 ENSDART00000174254
PAMR1 (1 of many)
si:ch211-102l7.3
chr25_-_4525081 1.22 ENSDART00000184347
pidd1
p53-induced death domain protein 1
chr22_+_18469004 1.21 ENSDART00000061430
cilp2
cartilage intermediate layer protein 2
chr12_-_28363111 1.21 ENSDART00000016283
ENSDART00000164156
psmd11b
proteasome 26S subunit, non-ATPase 11b
chr7_-_7692992 1.20 ENSDART00000192619
aadat
aminoadipate aminotransferase
chr17_+_2162916 1.20 ENSDART00000103775
pak6a
p21 protein (Cdc42/Rac)-activated kinase 6a
chr17_+_52524452 1.19 ENSDART00000016614
dlst
dihydrolipoamide S-succinyltransferase
chr24_+_9475809 1.19 ENSDART00000132688
si:ch211-285f17.1
si:ch211-285f17.1
chr8_+_24745041 1.19 ENSDART00000148872
slc16a4
solute carrier family 16, member 4
chr2_+_14992879 1.19 ENSDART00000137546
pimr55
Pim proto-oncogene, serine/threonine kinase, related 55
chr4_+_19700308 1.18 ENSDART00000027919
pax4
paired box 4
chr22_-_9183944 1.17 ENSDART00000188599
si:ch211-213a13.5
si:ch211-213a13.5
chr2_-_16216568 1.17 ENSDART00000173758
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr5_-_54672763 1.17 ENSDART00000159009
spag8
sperm associated antigen 8
chr12_+_20587179 1.16 ENSDART00000170127
arsg
arylsulfatase G
chr20_+_4060839 1.15 ENSDART00000178565
TRIM67
tripartite motif containing 67
chr6_+_6797520 1.14 ENSDART00000150967
si:ch211-85n16.3
si:ch211-85n16.3
chr4_+_25654686 1.14 ENSDART00000100714
acot16
acyl-CoA thioesterase 16
chr20_-_7583486 1.14 ENSDART00000144729
usp24
ubiquitin specific peptidase 24
chr7_+_4694924 1.14 ENSDART00000144873
si:ch211-225k7.3
si:ch211-225k7.3
chr14_+_32430982 1.14 ENSDART00000017179
ENSDART00000123382
ENSDART00000075593
f9a
coagulation factor IXa
chr22_+_14836291 1.14 ENSDART00000122740
gtpbp1l
GTP binding protein 1, like
chr7_+_24573721 1.12 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
si:dkeyp-75h12.7
chr25_-_37186894 1.11 ENSDART00000191647
ENSDART00000182095
tdrd12
tudor domain containing 12
chr6_+_3809346 1.11 ENSDART00000185105
FO704755.1

chr17_-_10122204 1.11 ENSDART00000160751
BX088587.1

chr9_-_394088 1.11 ENSDART00000169014
si:dkey-11f4.7
si:dkey-11f4.7
chr7_-_66868543 1.10 ENSDART00000149680
ampd3a
adenosine monophosphate deaminase 3a
chr8_-_53044089 1.10 ENSDART00000135982
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr2_-_7845110 1.09 ENSDART00000091987
si:ch211-38m6.7
si:ch211-38m6.7
chr9_+_11281969 1.09 ENSDART00000110691
wnt6b
wingless-type MMTV integration site family, member 6b
chr17_-_27048537 1.08 ENSDART00000050018
ENSDART00000193861
cnksr1
connector enhancer of kinase suppressor of Ras 1
chr2_+_36007449 1.07 ENSDART00000161837
lamc2
laminin, gamma 2
chr17_+_45602640 1.07 ENSDART00000153822
si:ch211-202f3.4
si:ch211-202f3.4
chr14_+_46313396 1.07 ENSDART00000047525
cryba1l1
crystallin, beta A1, like 1
chr15_-_46821568 1.06 ENSDART00000148525
chrd
chordin
chr1_+_27690 1.06 ENSDART00000162928
eed
embryonic ectoderm development
chr13_+_35528607 1.05 ENSDART00000075414
ENSDART00000112947
wdr27
WD repeat domain 27
chr22_-_14247276 1.05 ENSDART00000033332
si:ch211-246m6.5
si:ch211-246m6.5
chr24_+_21621654 1.03 ENSDART00000002595
rpl21
ribosomal protein L21
chr23_-_42232124 1.02 ENSDART00000149944
gpx7
glutathione peroxidase 7
chr8_-_13046089 1.02 ENSDART00000137784
si:dkey-208b23.5
si:dkey-208b23.5
chr3_+_52545014 1.01 ENSDART00000018908
slc27a1a
solute carrier family 27 (fatty acid transporter), member 1a
chr2_-_10877765 1.00 ENSDART00000100607
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr24_-_21847945 0.99 ENSDART00000189097
CR352265.4

chr7_+_49800849 0.99 ENSDART00000164838
ENSDART00000187888
PAMR1 (1 of many)
si:ch211-102l7.3
chr2_+_20406399 0.98 ENSDART00000006817
ENSDART00000137848
palmda
palmdelphin a
chr12_-_6880694 0.98 ENSDART00000171846
pcdh15b
protocadherin-related 15b
chr10_+_36197968 0.98 ENSDART00000114102
COA4
si:ch211-215a9.5
chr15_-_39955785 0.98 ENSDART00000154556
msh5
mutS homolog 5
chr13_+_31211050 0.97 ENSDART00000111705
ptpn20
protein tyrosine phosphatase, non-receptor type 20
chr7_-_17412559 0.97 ENSDART00000163020
nitr3a
novel immune-type receptor 3a
chr14_+_14806692 0.96 ENSDART00000193050
fhdc2
FH2 domain containing 2
chr9_+_29548195 0.96 ENSDART00000176057
rnf17
ring finger protein 17
chr10_+_5645887 0.95 ENSDART00000171426
pdzph1
PDZ and pleckstrin homology domains 1
chr6_-_28980756 0.94 ENSDART00000014661
glmnb
glomulin, FKBP associated protein b
chr15_-_40157331 0.94 ENSDART00000187958
si:ch211-281l24.3
si:ch211-281l24.3
chr6_-_58764672 0.94 ENSDART00000154322
soat2
sterol O-acyltransferase 2
chr15_-_40157513 0.93 ENSDART00000184014
si:ch211-281l24.3
si:ch211-281l24.3
chr20_+_10723292 0.93 ENSDART00000152805
si:ch211-182e10.4
si:ch211-182e10.4
chr8_-_2434282 0.93 ENSDART00000137262
ENSDART00000134044
vdac3
voltage-dependent anion channel 3
chr3_+_23029934 0.92 ENSDART00000110343
nags
N-acetylglutamate synthase
chr17_+_12285285 0.92 ENSDART00000154336
pimr174
Pim proto-oncogene, serine/threonine kinase, related 174
chr3_-_39180048 0.92 ENSDART00000049720
cdk21
cyclin-dependent kinase 21
chr6_-_52788213 0.92 ENSDART00000179880
rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like
chr5_+_12888260 0.92 ENSDART00000175916
gal3st1a
galactose-3-O-sulfotransferase 1a
chr8_-_45729248 0.92 ENSDART00000187736
BX088696.1

chr6_-_16948040 0.91 ENSDART00000156433
pimr30
Pim proto-oncogene, serine/threonine kinase, related 30
chr3_+_23029484 0.90 ENSDART00000187900
nags
N-acetylglutamate synthase
chr19_-_20403845 0.90 ENSDART00000151265
ENSDART00000147911
ENSDART00000151356
dazl
deleted in azoospermia-like
chr8_-_45729758 0.90 ENSDART00000189329
BX088696.1

chr12_-_48006835 0.90 ENSDART00000108989
adamts14
ADAM metallopeptidase with thrombospondin type 1 motif, 14
chr1_-_42289704 0.89 ENSDART00000150124
si:ch211-71k14.1
si:ch211-71k14.1
chr17_+_20589553 0.89 ENSDART00000154447
si:ch73-288o11.4
si:ch73-288o11.4
chr7_-_17425535 0.89 ENSDART00000098053
ENSDART00000161873
nitr3c
novel immune-type receptor 3c
chr16_+_21016820 0.89 ENSDART00000191861
BX571678.1

chr20_-_43663494 0.89 ENSDART00000144564
BX470188.1

chr23_-_16484383 0.89 ENSDART00000187839
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr17_-_48944465 0.89 ENSDART00000154110
si:ch1073-80i24.3
si:ch1073-80i24.3
chr3_-_12026741 0.88 ENSDART00000132238
cfap70
cilia and flagella associated protein 70
chr9_+_7724152 0.88 ENSDART00000061716
mnx2a
motor neuron and pancreas homeobox 2a
chr1_+_49668423 0.87 ENSDART00000150880
tsga10
testis specific, 10
chr11_-_40742424 0.87 ENSDART00000173399
ENSDART00000021369
tas1r3
taste receptor, type 1, member 3
chr6_-_17179637 0.86 ENSDART00000153710
pimr19
Pim proto-oncogene, serine/threonine kinase, related 19
chr6_-_16804001 0.86 ENSDART00000155398
pimr40
Pim proto-oncogene, serine/threonine kinase, related 40
chr22_+_14836040 0.86 ENSDART00000180951
gtpbp1l
GTP binding protein 1, like
chr6_-_17266221 0.85 ENSDART00000155448
pimr18
Pim proto-oncogene, serine/threonine kinase, related 18
chr3_-_10749691 0.85 ENSDART00000183088
CU210890.1

chr6_-_16735402 0.84 ENSDART00000154216
pimr44
Pim proto-oncogene, serine/threonine kinase, related 44
chr18_+_7073130 0.84 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
si:dkey-88e18.2
chr6_-_17112151 0.84 ENSDART00000153546
pimr17
Pim proto-oncogene, serine/threonine kinase, related 17
chr6_+_612594 0.84 ENSDART00000150903
kynu
kynureninase
chr16_-_27566552 0.83 ENSDART00000142102
zgc:153215
zgc:153215
chr10_+_26747755 0.83 ENSDART00000100329
f9b
coagulation factor IXb
chr6_-_59271270 0.83 ENSDART00000126870
ndufa4l2b
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2b
chr7_-_71531846 0.83 ENSDART00000111797
acer2
alkaline ceramidase 2
chr6_-_17052116 0.83 ENSDART00000156825
pimr45
Pim proto-oncogene, serine/threonine kinase, related 45
chr22_+_5532003 0.83 ENSDART00000106174
si:ch73-256j6.2
si:ch73-256j6.2
chr11_-_1935883 0.82 ENSDART00000172885
faim2b
Fas apoptotic inhibitory molecule 2b
chr6_-_16868834 0.81 ENSDART00000156503
pimr41
Pim proto-oncogene, serine/threonine kinase, related 41
chr18_+_35407921 0.81 ENSDART00000057733
zgc:153119
zgc:153119
chr17_-_29224908 0.81 ENSDART00000156288
si:dkey-28g23.6
si:dkey-28g23.6
chr22_+_23359369 0.80 ENSDART00000170886
dennd1b
DENN/MADD domain containing 1B
chr19_-_44955710 0.80 ENSDART00000165246
CSMD3 (1 of many)
si:ch211-233f16.1
chr11_-_10456387 0.80 ENSDART00000011087
ENSDART00000081827
ect2
epithelial cell transforming 2
chr2_+_19522082 0.80 ENSDART00000146098
pimr49
Pim proto-oncogene, serine/threonine kinase, related 49
chr8_-_25422186 0.80 ENSDART00000113492
ENSDART00000131736
kcnq2a
potassium voltage-gated channel, KQT-like subfamily, member 2a
chr7_+_4702269 0.80 ENSDART00000139880
si:ch211-225k7.4
si:ch211-225k7.4
chr13_-_38039871 0.80 ENSDART00000140645
CR456624.1

chr10_-_45029041 0.79 ENSDART00000167878
polm
polymerase (DNA directed), mu
chr9_+_1039215 0.79 ENSDART00000192186
DOCK9 (1 of many)
dedicator of cytokinesis 9
chr2_+_19578446 0.79 ENSDART00000164758
pimr50
Pim proto-oncogene, serine/threonine kinase, related 50
chr17_-_46817295 0.78 ENSDART00000155904
pimr24
Pim proto-oncogene, serine/threonine kinase, related 24
chr25_+_36345867 0.78 ENSDART00000186527
zgc:165555
zgc:165555
chr21_-_25522510 0.77 ENSDART00000162711
cnksr2b
connector enhancer of kinase suppressor of Ras 2b
chr17_+_2727807 0.77 ENSDART00000178759
kcnk10b
potassium channel, subfamily K, member 10b
chr12_-_3773869 0.77 ENSDART00000092983
si:ch211-166g5.4
si:ch211-166g5.4
chr9_-_7652792 0.77 ENSDART00000137957
dnajb2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr3_+_40164129 0.77 ENSDART00000102526
gfer
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr10_+_11261576 0.76 ENSDART00000155333
hsdl2
hydroxysteroid dehydrogenase like 2
chr5_+_6672870 0.76 ENSDART00000126598
pxna
paxillin a
chr12_+_47698356 0.76 ENSDART00000112010
lzts2b
leucine zipper, putative tumor suppressor 2b
chr1_-_46244523 0.76 ENSDART00000143908
si:ch211-138g9.3
si:ch211-138g9.3
chr15_+_37965953 0.75 ENSDART00000154192
si:dkey-238d18.10
si:dkey-238d18.10
chr11_-_29737088 0.75 ENSDART00000159828
si:ch211-218g23.6
si:ch211-218g23.6
chr8_+_10001805 0.74 ENSDART00000132894
si:dkey-8e10.2
si:dkey-8e10.2
chr7_+_71664624 0.74 ENSDART00000170273
emilin2b
elastin microfibril interfacer 2b
chr18_-_3473081 0.72 ENSDART00000174975
myo7aa
myosin VIIAa
chr2_+_42330828 0.72 ENSDART00000134802
ENSDART00000193783
ftr09
finTRIM family, member 9
chr19_-_20403318 0.72 ENSDART00000136826
dazl
deleted in azoospermia-like
chr15_-_39945036 0.72 ENSDART00000192481
msh5
mutS homolog 5
chr23_-_18024543 0.71 ENSDART00000139695
pm20d1.1
peptidase M20 domain containing 1, tandem duplicate 1
chr11_-_2838699 0.71 ENSDART00000066189
lhfpl5a
LHFPL tetraspan subfamily member 5a
chr10_+_42423318 0.71 ENSDART00000134282
npy8ar
neuropeptide Y receptor Y8a

Network of associatons between targets according to the STRING database.

First level regulatory network of pou1f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0046351 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
1.5 6.2 GO:0031446 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
1.2 3.6 GO:0010265 SCF complex assembly(GO:0010265)
0.6 2.3 GO:0014856 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.5 2.6 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.5 1.8 GO:0006526 arginine biosynthetic process(GO:0006526)
0.4 1.6 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.4 1.2 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.4 3.0 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.4 1.8 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.4 2.2 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.4 1.4 GO:0006531 aspartate metabolic process(GO:0006531)
0.3 1.0 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.3 2.2 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.3 0.8 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.3 4.3 GO:0006000 fructose metabolic process(GO:0006000)
0.3 1.3 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.3 1.3 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.2 1.5 GO:0005513 detection of calcium ion(GO:0005513)
0.2 0.7 GO:0071706 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.2 1.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 5.6 GO:0030497 fatty acid elongation(GO:0030497)
0.2 1.1 GO:0010159 specification of organ position(GO:0010159)
0.2 1.0 GO:0031650 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.2 6.0 GO:0030817 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.2 0.7 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.2 0.5 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.2 1.0 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.2 1.7 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 0.6 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.1 2.0 GO:0000272 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 5.3 GO:0032355 response to estradiol(GO:0032355)
0.1 1.6 GO:0016074 snoRNA metabolic process(GO:0016074)
0.1 0.7 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.9 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.4 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.4 GO:0042420 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.1 1.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 0.6 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.5 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.1 0.6 GO:0032875 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.1 0.6 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.9 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 1.3 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.9 GO:0034433 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.1 0.9 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.1 1.0 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.4 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.4 GO:0070285 pigment cell development(GO:0070285)
0.1 0.8 GO:0051013 microtubule severing(GO:0051013)
0.1 7.6 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.1 1.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.6 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1 0.3 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.1 0.6 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.2 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.3 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.1 1.1 GO:0032264 IMP salvage(GO:0032264)
0.1 0.6 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.1 0.4 GO:0036268 swimming(GO:0036268)
0.1 3.1 GO:0043113 receptor clustering(GO:0043113)
0.1 1.5 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.6 GO:0051601 exocyst localization(GO:0051601)
0.1 0.6 GO:0000303 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 2.1 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.1 0.9 GO:0061055 myotome development(GO:0061055)
0.1 3.9 GO:0006414 translational elongation(GO:0006414)
0.1 1.0 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.5 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.9 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 0.2 GO:0048618 embryonic digestive tract morphogenesis(GO:0048557) post-embryonic foregut morphogenesis(GO:0048618)
0.1 0.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.6 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 1.1 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 1.2 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.3 GO:0032475 otolith formation(GO:0032475)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 14.8 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 4.4 GO:0007283 spermatogenesis(GO:0007283)
0.0 2.7 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 3.4 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.8 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 2.4 GO:0007599 hemostasis(GO:0007599)
0.0 1.6 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 1.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.4 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 0.1 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.3 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.8 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.3 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.5 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 0.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.6 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.5 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 1.2 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.1 GO:0016571 histone methylation(GO:0016571)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.3 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.9 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.1 GO:0006415 translational termination(GO:0006415)
0.0 0.0 GO:0061549 sympathetic ganglion development(GO:0061549)
0.0 2.4 GO:1901605 alpha-amino acid metabolic process(GO:1901605)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.2 GO:0031673 H zone(GO:0031673)
1.1 4.3 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.5 7.6 GO:0005869 dynactin complex(GO:0005869)
0.4 2.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 0.6 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 1.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.8 GO:0043194 axon initial segment(GO:0043194)
0.1 1.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 2.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 3.0 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 0.9 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 2.1 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.6 GO:0044447 axoneme part(GO:0044447)
0.0 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 6.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.9 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0044545 NSL complex(GO:0044545)
0.0 0.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 4.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.5 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.8 GO:0030496 midbody(GO:0030496)
0.0 0.0 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.6 GO:0005902 microvillus(GO:0005902)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0008179 adenylate cyclase binding(GO:0008179)
1.7 5.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
1.4 5.6 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.7 4.7 GO:0045735 nutrient reservoir activity(GO:0045735)
0.6 1.8 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.6 1.8 GO:0034618 arginine binding(GO:0034618)
0.5 1.6 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.5 2.0 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.5 1.4 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.4 1.3 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.4 1.3 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.4 1.6 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.4 1.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.4 2.6 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.4 6.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.3 0.9 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.3 4.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.3 0.8 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 2.2 GO:0008494 translation activator activity(GO:0008494)
0.2 0.9 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.2 0.9 GO:0015288 porin activity(GO:0015288)
0.2 2.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 0.8 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 1.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.4 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.5 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.1 0.6 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.4 GO:0070699 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.9 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 1.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 1.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 3.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.3 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.1 1.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 1.0 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.6 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.7 GO:0038187 pattern recognition receptor activity(GO:0038187)
0.1 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.6 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 0.7 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.3 GO:0098634 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 3.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.2 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.1 0.2 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1 0.6 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.8 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.7 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.4 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.6 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 1.1 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 1.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.6 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.7 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 4.9 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.8 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.8 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 3.7 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.5 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 1.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.2 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 1.1 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 3.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 15.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 1.0 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID EPO PATHWAY EPO signaling pathway
0.0 0.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 6.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.3 3.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 6.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 2.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.8 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates