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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for ptf1a+si:dkey-34f9.3

Z-value: 1.44

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Transcription factors associated with ptf1a+si:dkey-34f9.3

Gene Symbol Gene ID Gene Info
ptf1a
ENSDARG00000014479 pancreas associated transcription factor 1a
si_dkey-34f9.3
ENSDARG00000077813 si_dkey-34f9.3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ptf1adr11_v1_chr2_+_29710857_29710857-0.534.9e-08Click!
si:dkey-34f9.3dr11_v1_chr9_+_45789887_45789887-0.481.1e-06Click!

Activity profile of ptf1a+si:dkey-34f9.3 motif

Sorted Z-values of ptf1a+si:dkey-34f9.3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_6172154 21.32 ENSDART00000185434
a1cf
apobec1 complementation factor
chr7_+_21841037 18.99 ENSDART00000077503
tm4sf5
transmembrane 4 L six family member 5
chr18_+_5490668 18.18 ENSDART00000167035
mibp2
muscle-specific beta 1 integrin binding protein 2
chr5_+_28848870 16.03 ENSDART00000149563
zgc:174259
zgc:174259
chr4_+_72797711 15.91 ENSDART00000190934
ENSDART00000163236
MYRFL
myelin regulatory factor-like
chr5_+_28849155 15.77 ENSDART00000079090
zgc:174259
zgc:174259
chr5_+_28857969 14.47 ENSDART00000149850
si:ch211-186e20.2
si:ch211-186e20.2
chr25_+_31227747 13.84 ENSDART00000033872
tnni2a.1
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr7_-_38644560 13.20 ENSDART00000114934
c6ast3
six-cysteine containing astacin protease 3
chr2_-_1514001 12.75 ENSDART00000057736
c8b
complement component 8, beta polypeptide
chr12_-_3940768 11.58 ENSDART00000134292
zgc:92040
zgc:92040
chr7_-_38644287 11.37 ENSDART00000182307
c6ast3
six-cysteine containing astacin protease 3
chr5_+_28858345 11.05 ENSDART00000111180
si:ch211-186e20.2
si:ch211-186e20.2
chr7_+_49664174 10.84 ENSDART00000137059
ENSDART00000131210
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr14_-_30390145 9.74 ENSDART00000045423
slc7a2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr2_-_59231017 9.12 ENSDART00000143980
ENSDART00000184190
ftr29
finTRIM family, member 29
chr2_-_59345920 9.07 ENSDART00000134662
ftr37
finTRIM family, member 37
chr13_+_9100 8.64 ENSDART00000165772
ppp4r3b
protein phosphatase 4, regulatory subunit 3B
chr13_-_25196758 8.49 ENSDART00000184722
adka
adenosine kinase a
chr18_-_45736 8.32 ENSDART00000148373
ENSDART00000148950
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr8_+_3379815 8.01 ENSDART00000155995
FUT9 (1 of many)
zgc:136963
chr11_-_27962757 7.92 ENSDART00000147386
ece1
endothelin converting enzyme 1
chr2_-_40199780 7.86 ENSDART00000113901
ccl34a.4
chemokine (C-C motif) ligand 34a, duplicate 4
chr19_-_617246 7.79 ENSDART00000062551
cyp51
cytochrome P450, family 51
chr9_-_17417628 7.54 ENSDART00000060425
ENSDART00000141997
ftr53
finTRIM family, member 53
chr16_+_35905031 7.44 ENSDART00000162411
sh3d21
SH3 domain containing 21
chr13_+_33452096 7.43 ENSDART00000057370
ftr80
finTRIM family, member 80
chr18_-_16801033 7.30 ENSDART00000100100
admb
adrenomedullin b
chr2_+_47927026 7.27 ENSDART00000143023
ftr25
finTRIM family, member 25
chr19_+_43750676 7.22 ENSDART00000165969
SLC17A3
si:ch1073-513e17.1
chr7_-_38638809 7.16 ENSDART00000144341
c6ast4
six-cysteine containing astacin protease 4
chr15_+_12435975 7.01 ENSDART00000168011
tmprss4a
transmembrane protease, serine 4a
chr10_-_15048781 6.83 ENSDART00000038401
ENSDART00000155674
si:ch211-95j8.2
si:ch211-95j8.2
chr21_-_20733615 6.78 ENSDART00000145544
si:ch211-22d5.2
si:ch211-22d5.2
chr15_-_37610434 6.66 ENSDART00000156856
CR848763.1

chr1_-_6085750 6.62 ENSDART00000138891
si:ch1073-345a8.1
si:ch1073-345a8.1
chr12_-_9132682 6.60 ENSDART00000066471
adam8b
ADAM metallopeptidase domain 8b
chr16_-_46567344 6.54 ENSDART00000127721
si:dkey-152b24.7
si:dkey-152b24.7
chr20_+_7084154 6.43 ENSDART00000136448
ftr85
finTRIM family, member 85
chr2_-_59327299 6.42 ENSDART00000133734
ftr36
finTRIM family, member 36
chr2_-_59265521 6.09 ENSDART00000146341
ENSDART00000097799
ftr33
finTRIM family, member 33
chr3_-_4579214 6.04 ENSDART00000164456
ftr50
finTRIM family, member 50
chr24_+_6353394 6.02 ENSDART00000165118
CR352329.1

chr10_-_45029041 5.83 ENSDART00000167878
polm
polymerase (DNA directed), mu
chr4_-_76488581 5.78 ENSDART00000174291
ftr51
finTRIM family, member 51
chr18_-_48530221 5.74 ENSDART00000188134
ENSDART00000142107
kcnj1a.2
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 2
chr3_+_301479 5.66 ENSDART00000165169
CABZ01075611.1

chr18_-_1414760 5.47 ENSDART00000171881
PEPD
peptidase D
chr24_-_6029314 5.43 ENSDART00000136155
ftr60
finTRIM family, member 60
chr3_+_3545825 5.39 ENSDART00000109060
CR589947.1

chr3_-_4591643 5.39 ENSDART00000138144
ftr50
finTRIM family, member 50
chr15_+_12436220 5.39 ENSDART00000169894
tmprss4a
transmembrane protease, serine 4a
chr2_-_42628028 5.36 ENSDART00000179866
myo10
myosin X
chr18_-_18543358 5.21 ENSDART00000126460
il34
interleukin 34
chr23_-_6865946 5.08 ENSDART00000056426
ftr58
finTRIM family, member 58
chr7_+_24523017 4.96 ENSDART00000077047
btr09
bloodthirsty-related gene family, member 9
chr23_-_46020226 4.90 ENSDART00000160010
SYDE2
synapse defective Rho GTPase homolog 2
chr18_-_502722 4.89 ENSDART00000185757
sdr42e1
short chain dehydrogenase/reductase family 42E, member 1
chr9_+_3153717 4.88 ENSDART00000191958
si:zfos-979f1.2
si:zfos-979f1.2
chr3_-_32934359 4.84 ENSDART00000124160
aoc2
amine oxidase, copper containing 2
chr2_+_47935476 4.53 ENSDART00000140555
ftr26
finTRIM family, member 26
chr3_-_34624745 4.46 ENSDART00000151091
tac4
tachykinin 4 (hemokinin)
chr3_-_54524194 4.22 ENSDART00000155406
ENSDART00000111791
si:ch73-208g10.1
si:ch73-208g10.1
chr9_+_3153466 4.20 ENSDART00000135619
si:zfos-979f1.2
si:zfos-979f1.2
chr5_+_37854685 4.18 ENSDART00000051222
ENSDART00000185283
ins
preproinsulin
chr22_-_20695237 4.13 ENSDART00000112722
org
oogenesis-related gene
chr3_-_4557653 4.12 ENSDART00000111305
ftr50
finTRIM family, member 50
chr3_+_18097700 4.07 ENSDART00000021634
wfikkn2a
info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a
chr15_-_35134918 4.07 ENSDART00000157196
si:ch211-272b8.7
si:ch211-272b8.7
chr3_-_48980319 3.99 ENSDART00000165319
ftr42
finTRIM family, member 42
chr3_+_4997545 3.97 ENSDART00000181237
CABZ01117706.1

chr2_-_59376399 3.94 ENSDART00000137134
ftr38
finTRIM family, member 38
chr7_+_41812190 3.94 ENSDART00000113732
ENSDART00000174137
orc6
origin recognition complex, subunit 6
chr18_+_3140682 3.92 ENSDART00000166382
clns1a
chloride channel, nucleotide-sensitive, 1A
chr19_-_12212692 3.81 ENSDART00000142077
ENSDART00000151599
ENSDART00000140834
ENSDART00000078781
znf706
zinc finger protein 706
chr10_+_10386435 3.80 ENSDART00000179214
ENSDART00000189799
ENSDART00000193875
sardh
sarcosine dehydrogenase
chr4_+_77681389 3.80 ENSDART00000099727
gbp4
guanylate binding protein 4
chr6_-_58975010 3.78 ENSDART00000144911
ENSDART00000144514
mars
methionyl-tRNA synthetase
chr9_+_343062 3.73 ENSDART00000164012
ENSDART00000164365
bpifcl
BPI fold containing family C, like
chr15_-_37620167 3.71 ENSDART00000059582
si:ch211-137j23.8
si:ch211-137j23.8
chr2_-_43130812 3.70 ENSDART00000039079
ENSDART00000056162
ftr13
finTRIM family, member 13
chr1_-_59407322 3.66 ENSDART00000161661
si:ch211-188p14.5
si:ch211-188p14.5
chr2_-_59178742 3.62 ENSDART00000170594
ENSDART00000109246
ftr95
finTRIM family, member 95
chr16_-_46572834 3.58 ENSDART00000115248
zgc:174938
zgc:174938
chr7_+_29177191 3.54 ENSDART00000008096
aph1b
APH1B gamma secretase subunit
chr15_-_2519640 3.51 ENSDART00000047013
srprb
signal recognition particle receptor, B subunit
chr2_-_44368824 3.45 ENSDART00000155662
si:ch211-265g22.4
si:ch211-265g22.4
chr21_+_45819662 3.44 ENSDART00000193362
ENSDART00000184255
pitx1
paired-like homeodomain 1
chr17_+_21477892 3.35 ENSDART00000155309
pla2g4f.2
phospholipase A2, group IVF, tandem duplicate 2
chr25_+_37297659 3.33 ENSDART00000086733
si:dkey-234i14.13
si:dkey-234i14.13
chr7_+_41812636 3.30 ENSDART00000174333
orc6
origin recognition complex, subunit 6
chr2_-_14793343 3.28 ENSDART00000132264
si:ch73-366i20.1
si:ch73-366i20.1
chr3_-_61592417 3.23 ENSDART00000155082
nptx2a
neuronal pentraxin 2a
chr11_-_2478374 3.19 ENSDART00000173205
si:ch73-267c23.10
si:ch73-267c23.10
chr11_-_16021424 3.10 ENSDART00000193291
ENSDART00000170731
ENSDART00000104107
zgc:173544
zgc:173544
chr4_-_38281909 3.00 ENSDART00000162448
si:ch211-229l10.9
si:ch211-229l10.9
chr5_+_62723233 2.98 ENSDART00000183718
nanos2
nanos homolog 2
chr8_+_14959587 2.90 ENSDART00000138548
ENSDART00000041697
abl2
c-abl oncogene 2, non-receptor tyrosine kinase
chr25_+_37285737 2.90 ENSDART00000126879
tmed6
transmembrane p24 trafficking protein 6
chr2_-_59205393 2.74 ENSDART00000056417
ENSDART00000182452
ENSDART00000141876
ftr30
finTRIM family, member 30
chr22_-_36690742 2.69 ENSDART00000017188
ENSDART00000124698
ncl
nucleolin
chr1_-_58009216 2.56 ENSDART00000143829
nxnl1
nucleoredoxin like 1
chr4_-_58964138 2.55 ENSDART00000150259
si:ch211-64i20.3
si:ch211-64i20.3
chr3_+_37649436 2.54 ENSDART00000075039
gosr2
golgi SNAP receptor complex member 2
chr12_+_18663154 2.46 ENSDART00000057918
si:ch211-147h1.4
si:ch211-147h1.4
chr7_+_41812817 2.35 ENSDART00000174165
orc6
origin recognition complex, subunit 6
chr16_-_46573211 2.30 ENSDART00000193392
zgc:174938
zgc:174938
chr4_-_7231480 2.29 ENSDART00000159436
si:ch211-170p16.1
si:ch211-170p16.1
chr16_-_11961325 2.24 ENSDART00000143845
si:ch73-296e2.3
si:ch73-296e2.3
chr7_+_5904020 2.19 ENSDART00000172847
hist1h2a11
histone cluster 1 H2A family member 11
chr22_+_15633013 2.14 ENSDART00000188095
ENSDART00000048763
CABZ01090041.1

chr4_-_65323874 2.10 ENSDART00000175271
ENSDART00000187913
BX571813.1

chr19_+_7895086 2.09 ENSDART00000132180
si:dkey-266f7.1
si:dkey-266f7.1
chr23_+_5736226 2.05 ENSDART00000134527
ENSDART00000112220
ftr57
finTRIM family, member 57
chr21_-_1642739 2.05 ENSDART00000151118
zgc:152948
zgc:152948
chr15_-_41523225 2.01 ENSDART00000141202
ENSDART00000099290
ENSDART00000170395
ENSDART00000099437
si:dkey-230i18.2
si:dkey-121n8.7
nlrc9
si:dkey-230i18.2
si:dkey-121n8.7
NLR family CARD domain containing 9
chr8_+_4333914 2.00 ENSDART00000137528
myl2b
myosin, light chain 2b, regulatory, cardiac, slow
chr16_-_30932533 2.00 ENSDART00000085761
slc45a4
solute carrier family 45, member 4
chr25_-_37314700 1.93 ENSDART00000017807
igl4v8
immunoglobulin light 4 variable 8
chr15_-_34933560 1.91 ENSDART00000006288
dhx16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr17_-_30473374 1.88 ENSDART00000155021
si:ch211-175f11.5
si:ch211-175f11.5
chr22_-_17489040 1.86 ENSDART00000141286
si:ch211-197g15.6
si:ch211-197g15.6
chr3_-_58585854 1.84 ENSDART00000123546
CABZ01038521.1

chr1_+_57311901 1.83 ENSDART00000149397
mycbpap
mycbp associated protein
chr3_+_5504990 1.81 ENSDART00000143626
si:ch73-264i18.2
si:ch73-264i18.2
chr24_+_26088143 1.76 ENSDART00000171129
CR352209.1

chr1_-_59567685 1.73 ENSDART00000159144
ENSDART00000182913
zmp:0000001082
zmp:0000001082
chr1_-_59287410 1.63 ENSDART00000158011
ENSDART00000170580
col5a3b
collagen, type V, alpha 3b
chr22_-_9677264 1.59 ENSDART00000181737
si:dkey-286j17.4
si:dkey-286j17.4
chr8_-_1267247 1.59 ENSDART00000150064
cdc14b
cell division cycle 14B
chr15_-_5207805 1.55 ENSDART00000174046
or128-7
odorant receptor, family E, subfamily 128, member 7
chr15_-_5262942 1.54 ENSDART00000138003
or127-1
odorant receptor, family E, subfamily 127, member 1
chr23_-_10914275 1.44 ENSDART00000112965
pdzrn3a
PDZ domain containing RING finger 3a
chr8_-_22274222 1.39 ENSDART00000131805
nphp4
nephronophthisis 4
chr2_+_42260021 1.37 ENSDART00000124702
ENSDART00000140203
ENSDART00000184079
ENSDART00000193349
ftr04
finTRIM family, member 4
chr2_-_47904043 1.27 ENSDART00000185328
ENSDART00000126740
ftr22
finTRIM family, member 22
chr3_+_62196672 1.25 ENSDART00000097312
sco1
SCO1 cytochrome c oxidase assembly protein
chr19_-_15434813 1.23 ENSDART00000019843
ftr55
finTRIM family, member 55
chr8_+_54263946 1.22 ENSDART00000193119
TMCC1 (1 of many)
transmembrane and coiled-coil domain family 1
chr4_-_33525219 1.13 ENSDART00000150491
CT027801.2

chr15_-_35098345 1.10 ENSDART00000181824
CR387932.1

chr25_+_36336920 1.10 ENSDART00000073402
hist1h2a1
histone cluster 1 H2A family member1
chr15_+_2475894 1.08 ENSDART00000035939
panx1a
pannexin 1a
chr1_+_54835131 1.03 ENSDART00000145070
si:ch211-196h16.4
si:ch211-196h16.4
chr1_+_26467071 1.03 ENSDART00000112329
ENSDART00000159318
ENSDART00000193833
ENSDART00000011809
uso1
USO1 vesicle transport factor
chr8_-_36554675 1.02 ENSDART00000132804
ENSDART00000078746
ccdc157
coiled-coil domain containing 157
chr18_-_50921002 1.00 ENSDART00000017053
ENSDART00000008696
cttn
cortactin
chr4_+_40018440 0.99 ENSDART00000110827
si:dkey-199k11.6
si:dkey-199k11.6
chr20_+_46183505 0.90 ENSDART00000060799
taar13b
trace amine associated receptor 13b
chr21_+_244503 0.89 ENSDART00000162889
stard4
StAR-related lipid transfer (START) domain containing 4
chr22_+_22438783 0.74 ENSDART00000147825
kif14
kinesin family member 14
chr21_+_20356458 0.72 ENSDART00000135816
pde6b
phosphodiesterase 6B, cGMP-specific, rod, beta
chr12_-_37343858 0.67 ENSDART00000153281
tekt3
tektin 3
chr1_-_65017 0.57 ENSDART00000168609
si:zfos-1011f11.2
si:zfos-1011f11.2
chr5_+_38096729 0.51 ENSDART00000135428
si:ch211-284e13.5
si:ch211-284e13.5
chr4_-_33371634 0.46 ENSDART00000150712
si:dkeyp-4f2.3
si:dkeyp-4f2.3
chr25_-_15496485 0.43 ENSDART00000140245
si:dkeyp-67e1.6
si:dkeyp-67e1.6
chr2_+_42294944 0.39 ENSDART00000140599
ENSDART00000178811
ftr06
finTRIM family, member 6
chr21_-_19906388 0.35 ENSDART00000114969
mfhas1
malignant fibrous histiocytoma amplified sequence 1
chr15_-_42736433 0.35 ENSDART00000154379
si:ch211-181d7.1
si:ch211-181d7.1
chr10_+_506538 0.35 ENSDART00000141713
si:ch211-242f23.3
si:ch211-242f23.3
chr20_+_53278746 0.33 ENSDART00000074249
gpr6
G protein-coupled receptor 6
chr15_-_46828958 0.33 ENSDART00000045110
chrd
chordin
chr8_+_16758304 0.32 ENSDART00000133514
elovl7a
ELOVL fatty acid elongase 7a
chr23_+_9353552 0.28 ENSDART00000163298
BX511246.1

chr18_-_41754020 0.15 ENSDART00000077898
grk7b
G protein-coupled receptor kinase 7b
chr11_+_45347961 0.10 ENSDART00000172962
si:ch73-100l22.3
si:ch73-100l22.3
chr17_-_86548 0.09 ENSDART00000163657
grem1b
gremlin 1b
chr3_-_20721064 0.08 ENSDART00000193532
spop
speckle-type POZ protein

Network of associatons between targets according to the STRING database.

First level regulatory network of ptf1a+si:dkey-34f9.3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.3 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
2.3 11.6 GO:0010133 proline catabolic process to glutamate(GO:0010133)
2.2 6.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
1.7 5.2 GO:0045649 regulation of macrophage differentiation(GO:0045649)
1.6 9.7 GO:1902837 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
1.5 21.3 GO:0016556 mRNA modification(GO:0016556)
1.4 8.5 GO:0044209 AMP salvage(GO:0044209)
1.3 3.8 GO:1901052 sarcosine metabolic process(GO:1901052)
1.0 4.2 GO:0030858 positive regulation of epithelial cell differentiation(GO:0030858) negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.9 4.5 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.7 57.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.6 18.2 GO:0070831 basement membrane assembly(GO:0070831)
0.6 3.8 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.5 7.9 GO:0016486 peptide hormone processing(GO:0016486)
0.5 12.7 GO:0019835 cytolysis(GO:0019835)
0.4 3.3 GO:0051673 membrane disruption in other organism(GO:0051673)
0.4 3.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.4 3.5 GO:0007220 Notch receptor processing(GO:0007220)
0.3 9.6 GO:0006270 DNA replication initiation(GO:0006270)
0.3 1.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.3 7.8 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.2 12.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 0.9 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.2 2.7 GO:0009303 rRNA transcription(GO:0009303)
0.2 5.8 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.2 5.3 GO:0002377 immunoglobulin production(GO:0002377)
0.2 1.9 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 3.7 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.2 6.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.2 7.9 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.2 15.9 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.2 3.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.2 3.2 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.2 1.6 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.2 1.1 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 3.9 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 3.5 GO:0045047 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.1 4.1 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 2.2 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.1 5.7 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 5.4 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 6.4 GO:0051607 defense response to virus(GO:0051607)
0.1 4.9 GO:0006694 steroid biosynthetic process(GO:0006694)
0.1 2.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 1.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.3 GO:0010159 specification of organ position(GO:0010159)
0.1 8.7 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.1 4.8 GO:0009308 amine metabolic process(GO:0009308)
0.1 0.7 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 1.9 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 3.2 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 30.7 GO:1902680 positive regulation of transcription, DNA-templated(GO:0045893) positive regulation of RNA biosynthetic process(GO:1902680) positive regulation of nucleic acid-templated transcription(GO:1903508)
0.0 3.0 GO:0048477 oogenesis(GO:0048477)
0.0 2.9 GO:0007030 Golgi organization(GO:0007030)
0.0 3.7 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 1.4 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 28.2 GO:0006508 proteolysis(GO:0006508)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 7.0 GO:0007346 regulation of mitotic cell cycle(GO:0007346)
0.0 0.3 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 3.2 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 4.3 GO:0016567 protein ubiquitination(GO:0016567)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
1.3 3.9 GO:0034709 methylosome(GO:0034709)
0.8 9.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.8 12.7 GO:0005579 membrane attack complex(GO:0005579)
0.4 3.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.3 12.7 GO:0005861 troponin complex(GO:0005861)
0.2 3.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 44.0 GO:0000785 chromatin(GO:0000785)
0.1 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 3.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 2.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 1.4 GO:0097546 ciliary base(GO:0097546)
0.1 2.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 66.5 GO:0005615 extracellular space(GO:0005615)
0.0 1.1 GO:0005921 gap junction(GO:0005921)
0.0 5.4 GO:0016459 myosin complex(GO:0016459)
0.0 0.7 GO:0036126 sperm flagellum(GO:0036126)
0.0 8.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 3.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.2 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.6 GO:0072686 mitotic spindle(GO:0072686)
0.0 6.2 GO:0005938 cell cortex(GO:0005938)
0.0 3.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 11.6 GO:0005739 mitochondrion(GO:0005739)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.6 GO:0004657 proline dehydrogenase activity(GO:0004657)
2.6 18.2 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
1.7 8.5 GO:0004001 adenosine kinase activity(GO:0004001)
1.5 4.5 GO:0031834 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
1.4 9.7 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
1.0 4.8 GO:0008131 primary amine oxidase activity(GO:0008131)
1.0 3.8 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.5 4.9 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.5 61.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.4 5.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.3 21.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.3 3.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 5.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 8.3 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.2 36.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 1.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 12.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 3.7 GO:0004875 complement receptor activity(GO:0004875)
0.2 7.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 7.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 2.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 5.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.9 GO:0003785 actin monomer binding(GO:0003785)
0.1 94.3 GO:0008270 zinc ion binding(GO:0008270)
0.1 10.2 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.1 0.5 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 4.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 3.5 GO:0030674 protein binding, bridging(GO:0030674)
0.0 5.2 GO:0005126 cytokine receptor binding(GO:0005126)
0.0 3.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 2.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 1.9 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 6.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 3.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 2.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 11.6 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.3 5.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 4.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 3.6 PID ARF 3PATHWAY Arf1 pathway
0.1 2.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 3.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 5.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.6 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.5 12.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.4 9.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 4.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.4 3.5 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.2 3.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 5.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 6.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 3.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 3.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 13.8 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.1 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 8.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 4.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor