Project
PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish
Navigation
Downloads
Results for rreb1a+rreb1b
Z-value: 2.60
Motif logo
Transcription factors associated with rreb1a+rreb1b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| rreb1a | dr11_v1_chr24_-_2381143_2381143 | 0.28 | 6.0e-03 | Click! |
| rreb1b | dr11_v1_chr2_+_21000334_21000355 | 0.15 | 1.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_-_10606 Show fit | 48.09 |
ENSDART00000192650
ENSDART00000186761 |
|
|
| chr5_+_817016 Show fit | 45.01 |
ENSDART00000188498
|
|
|
| chr5_+_828663 Show fit | 45.00 |
ENSDART00000181776
|
|
|
| chr4_-_77563411 Show fit | 33.41 |
ENSDART00000186841
|
|
|
| chr21_+_28445052 Show fit | 32.59 |
ENSDART00000077871
|
phosphorylase, glycogen, muscle A |
|
| chr4_-_77551860 Show fit | 32.45 |
ENSDART00000188176
|
|
|
| chr17_-_122680 Show fit | 30.08 |
ENSDART00000066430
|
actin, alpha, cardiac muscle 1b |
|
| chr8_+_54284961 Show fit | 29.22 |
ENSDART00000122692
|
plexin D1 |
|
| chr12_+_13244149 Show fit | 27.12 |
ENSDART00000186984
ENSDART00000105896 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like |
|
| chr4_+_90048 Show fit | 26.85 |
ENSDART00000166440
|
low density lipoprotein receptor-related protein 6 |
Network of associatons between targets according to the STRING database.
First level regulatory network of rreb1a+rreb1b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.3 | 53.1 | GO:0070836 | membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836) |
| 10.9 | 32.6 | GO:0052575 | carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576) |
| 0.6 | 29.4 | GO:0060028 | convergent extension involved in axis elongation(GO:0060028) |
| 1.4 | 29.2 | GO:1902287 | semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287) |
| 4.0 | 28.2 | GO:0071623 | negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623) |
| 6.0 | 24.0 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 0.1 | 22.2 | GO:0046777 | protein autophosphorylation(GO:0046777) |
| 7.3 | 21.8 | GO:0014722 | regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.8 | 21.3 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
| 1.9 | 21.2 | GO:0030240 | skeletal muscle thin filament assembly(GO:0030240) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 53.1 | GO:0005901 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
| 0.3 | 34.2 | GO:0016607 | nuclear speck(GO:0016607) |
| 1.9 | 30.1 | GO:0005869 | dynactin complex(GO:0005869) |
| 1.4 | 29.2 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.2 | 25.3 | GO:0005882 | intermediate filament(GO:0005882) |
| 1.2 | 24.7 | GO:0031430 | M band(GO:0031430) |
| 0.1 | 24.6 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 3.1 | 21.8 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.9 | 21.5 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.2 | 18.7 | GO:0005924 | cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 61.1 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.0 | 39.0 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
| 6.5 | 32.6 | GO:0008184 | phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184) |
| 0.4 | 31.8 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.3 | 30.5 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.9 | 29.2 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.1 | 25.5 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 6.0 | 24.0 | GO:0008746 | NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652) |
| 2.7 | 23.9 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
| 0.3 | 22.0 | GO:0016879 | ligase activity, forming carbon-nitrogen bonds(GO:0016879) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 42.9 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.3 | 39.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.4 | 30.6 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 1.0 | 28.7 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 1.1 | 27.0 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 1.3 | 15.7 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.5 | 12.8 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.2 | 12.3 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.4 | 11.4 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.4 | 9.8 | PID IL3 PATHWAY | IL3-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 38.4 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 1.6 | 29.2 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.6 | 23.9 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.8 | 22.2 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 1.7 | 20.2 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.3 | 15.6 | REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | Genes involved in SCF-beta-TrCP mediated degradation of Emi1 |
| 0.4 | 12.6 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.6 | 12.3 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.5 | 12.1 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.2 | 11.4 | REACTOME SIGNALING BY ERBB4 | Genes involved in Signaling by ERBB4 |