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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for runx1

Z-value: 1.99

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Transcription factors associated with runx1

Gene Symbol Gene ID Gene Info
runx1
ENSDARG00000087646 RUNX family transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
runx1dr11_v1_chr1_-_1402303_14023030.279.2e-03Click!

Activity profile of runx1 motif

Sorted Z-values of runx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_7810348 24.60 ENSDART00000171984
cxcl19
chemokine (C-X-C motif) ligand 19
chr17_-_2039511 21.89 ENSDART00000160223
spint1a
serine peptidase inhibitor, Kunitz type 1 a
chr18_+_5543677 20.01 ENSDART00000146161
ENSDART00000136189
nnt2
nicotinamide nucleotide transhydrogenase 2
chr7_+_22637515 19.93 ENSDART00000158698
si:dkey-112a7.5
si:dkey-112a7.5
chr14_+_38786298 19.72 ENSDART00000164440
si:ch211-195b11.3
si:ch211-195b11.3
chr20_-_14054083 19.33 ENSDART00000009549
rhag
Rh associated glycoprotein
chr7_+_31879986 17.28 ENSDART00000138491
mybpc3
myosin binding protein C, cardiac
chr23_+_36653376 16.63 ENSDART00000053189
gpr182
G protein-coupled receptor 182
chr3_-_16784280 16.24 ENSDART00000137108
ENSDART00000137276
si:dkey-30j10.5
si:dkey-30j10.5
chr7_+_31879649 15.97 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr19_-_40191358 15.87 ENSDART00000183919
grn1
granulin 1
chr5_+_57658898 15.81 ENSDART00000074268
ENSDART00000124568
zgc:153929
zgc:153929
chr16_+_11724230 15.34 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr8_+_47099033 15.05 ENSDART00000142979
arhgef16
Rho guanine nucleotide exchange factor (GEF) 16
chr8_+_19356072 14.44 ENSDART00000063272
mpeg1.2
macrophage expressed 1, tandem duplicate 2
chr22_+_34616151 14.02 ENSDART00000155399
ENSDART00000104705
si:ch1073-214b20.2
si:ch1073-214b20.2
chr18_+_35742838 13.51 ENSDART00000088504
ENSDART00000140386
rasgrp4
RAS guanyl releasing protein 4
chr4_+_77973876 12.76 ENSDART00000057423
terfa
telomeric repeat binding factor a
chr17_-_8862424 12.66 ENSDART00000064633
nkl.4
NK-lysin tandem duplicate 4
chr15_-_12011390 12.50 ENSDART00000187403
si:dkey-202l22.6
si:dkey-202l22.6
chr1_-_38195012 12.05 ENSDART00000020409
hand2
heart and neural crest derivatives expressed 2
chr24_-_25244637 11.77 ENSDART00000153798
hhla2b.2
HERV-H LTR-associating 2b, tandem duplicate 2
chr1_+_55140970 11.68 ENSDART00000039807
mb
myoglobin
chr9_+_23770666 11.46 ENSDART00000182493
si:ch211-219a4.3
si:ch211-219a4.3
chr10_+_17088261 11.44 ENSDART00000132103
si:dkey-106l3.7
si:dkey-106l3.7
chr7_+_24523017 11.35 ENSDART00000077047
btr09
bloodthirsty-related gene family, member 9
chr4_-_20043484 11.20 ENSDART00000167780
zgc:193726
zgc:193726
chr5_-_30615901 11.19 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr19_-_7144548 11.09 ENSDART00000147177
ENSDART00000134850
psmb8a
psmb13a
proteasome subunit beta 8A
proteasome subunit beta 13a
chr4_-_77557279 10.97 ENSDART00000180113
AL935186.10

chr19_-_40192249 10.67 ENSDART00000051972
grn1
granulin 1
chr18_+_31073265 10.63 ENSDART00000023539
cyba
cytochrome b-245, alpha polypeptide
chr19_+_5640504 10.60 ENSDART00000179987
ft2
alpha(1,3)fucosyltransferase gene 2
chr2_-_37465517 10.48 ENSDART00000139983
si:dkey-57k2.6
si:dkey-57k2.6
chr17_-_8899323 10.46 ENSDART00000081590
nkl.1
NK-lysin tandem duplicate 1
chr11_+_24703108 10.34 ENSDART00000159173
gpr25
G protein-coupled receptor 25
chr7_-_17337233 10.29 ENSDART00000050236
ENSDART00000102141
nitr8
novel immune-type receptor 8
chr13_-_39947335 9.97 ENSDART00000056996
sfrp5
secreted frizzled-related protein 5
chr11_+_21076872 9.88 ENSDART00000155521
prelp
proline/arginine-rich end leucine-rich repeat protein
chr4_-_13502549 9.75 ENSDART00000140366
si:ch211-266a5.12
si:ch211-266a5.12
chr5_+_13373593 9.67 ENSDART00000051668
ENSDART00000183883
ccl19a.2
chemokine (C-C motif) ligand 19a, tandem duplicate 2
chr1_-_34335752 9.66 ENSDART00000140157
si:dkey-24h22.5
si:dkey-24h22.5
chr6_-_39764995 9.58 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr10_-_15128771 9.52 ENSDART00000101261
spp1
secreted phosphoprotein 1
chr4_-_68563862 9.41 ENSDART00000182970
BX548011.2

chr17_+_1627379 9.36 ENSDART00000184050
LO018432.1

chr22_+_21255860 9.34 ENSDART00000134893
cpamd8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr10_+_43994471 9.34 ENSDART00000138242
ENSDART00000186359
cldn5b
claudin 5b
chr22_-_31020690 9.33 ENSDART00000130604
ssuh2.4
ssu-2 homolog, tandem duplicate 4
chr25_-_3470910 9.15 ENSDART00000029067
ENSDART00000186737
hbp1
HMG-box transcription factor 1
chr1_-_12027 9.15 ENSDART00000164359
rpl24
ribosomal protein L24
chr1_-_57629639 9.11 ENSDART00000158984
zmp:0000001289
zmp:0000001289
chr16_-_17056630 9.10 ENSDART00000138715
plekhg6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr15_-_23376541 9.06 ENSDART00000078570
c1qtnf5
C1q and TNF related 5
chr14_-_11430566 8.88 ENSDART00000137154
ENSDART00000091158
irg1l
immunoresponsive gene 1, like
chr11_-_30630628 8.87 ENSDART00000103265
zgc:158773
zgc:158773
chr10_-_43771447 8.86 ENSDART00000052307
arrdc3b
arrestin domain containing 3b
chr8_+_21353878 8.85 ENSDART00000056420
alas2
aminolevulinate, delta-, synthase 2
chr2_+_32796873 8.85 ENSDART00000077511
ccr9a
chemokine (C-C motif) receptor 9a
chr24_+_19518570 8.71 ENSDART00000056081
sulf1
sulfatase 1
chr19_-_3821678 8.70 ENSDART00000169639
si:dkey-206d17.12
si:dkey-206d17.12
chr13_-_33170733 8.66 ENSDART00000057382
fbln5
fibulin 5
chr19_-_5372572 8.62 ENSDART00000151326
krt17
keratin 17
chr9_+_30464641 8.60 ENSDART00000128357
gja5a
gap junction protein, alpha 5a
chr1_+_55703120 8.57 ENSDART00000141089
adgre6
adhesion G protein-coupled receptor E6
chr3_-_34022076 8.55 ENSDART00000150907
ENSDART00000151092
ighv1-4
ighv1-4
immunoglobulin heavy variable 1-4
immunoglobulin heavy variable 1-4
chr1_+_54650048 8.52 ENSDART00000141207
si:ch211-202h22.7
si:ch211-202h22.7
chr25_+_4751879 8.48 ENSDART00000169465
si:zfos-2372e4.1
si:zfos-2372e4.1
chr25_-_13202208 8.46 ENSDART00000168155
si:ch211-194m7.4
si:ch211-194m7.4
chr2_+_51028269 8.44 ENSDART00000161254
eef1da
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr25_-_23526058 8.37 ENSDART00000191331
ENSDART00000062930
phlda2
pleckstrin homology-like domain, family A, member 2
chr14_+_30279391 8.33 ENSDART00000172794
fgl1
fibrinogen-like 1
chr13_-_20381485 8.32 ENSDART00000131351
si:ch211-270n8.1
si:ch211-270n8.1
chr7_+_39706004 8.30 ENSDART00000161856
ccl36.1
chemokine (C-C motif) ligand 36, duplicate 1
chr3_+_3598555 8.22 ENSDART00000191152
CR589947.3

chr17_+_6563307 8.20 ENSDART00000156454
adgrf3a
adhesion G protein-coupled receptor F3a
chr6_-_15096556 8.17 ENSDART00000185327
fhl2b
four and a half LIM domains 2b
chr22_-_5323482 8.12 ENSDART00000145785
s1pr4
sphingosine-1-phosphate receptor 4
chr13_-_25305179 8.08 ENSDART00000110064
plaua
plasminogen activator, urokinase a
chr18_+_22109379 8.05 ENSDART00000147230
zgc:158868
zgc:158868
chr6_-_43449013 8.00 ENSDART00000122423
eevs
2-epi-5-epi-valiolone synthase
chr24_-_25098719 7.98 ENSDART00000193651
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr4_-_16353733 7.92 ENSDART00000186785
lum
lumican
chr12_+_34273240 7.90 ENSDART00000037904
socs3b
suppressor of cytokine signaling 3b
chr7_+_22691961 7.90 ENSDART00000041615
ugt5g1
UDP glucuronosyltransferase 5 family, polypeptide G1
chr21_+_11248448 7.87 ENSDART00000142431
arid6
AT-rich interaction domain 6
chr19_+_3849378 7.86 ENSDART00000166218
ENSDART00000159228
oscp1a
organic solute carrier partner 1a
chr10_+_24692076 7.85 ENSDART00000181600
tpte
transmembrane phosphatase with tensin homology
chr13_+_25396896 7.84 ENSDART00000041257
gsto2
glutathione S-transferase omega 2
chr23_-_37575030 7.84 ENSDART00000031875
tor1l3
torsin family 1 like 3
chr22_+_22004082 7.82 ENSDART00000148375
gna15.2
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 2
chr17_-_6382392 7.81 ENSDART00000188051
ENSDART00000192560
ENSDART00000137389
ENSDART00000115389
txlnbb
taxilin beta b
chr2_-_40199780 7.81 ENSDART00000113901
ccl34a.4
chemokine (C-C motif) ligand 34a, duplicate 4
chr15_+_36054864 7.80 ENSDART00000156697
col4a3
collagen, type IV, alpha 3
chr21_+_22985078 7.70 ENSDART00000156491
lpar6b
lysophosphatidic acid receptor 6b
chr4_-_12795436 7.63 ENSDART00000131026
ENSDART00000075127
b2m
beta-2-microglobulin
chr22_-_8860869 7.54 ENSDART00000166188
CABZ01046427.2

chr20_+_98179 7.43 ENSDART00000022725
si:ch1073-155h21.1
si:ch1073-155h21.1
chr13_-_37122217 7.39 ENSDART00000133242
syne2b
spectrin repeat containing, nuclear envelope 2b
chr1_-_9228007 7.38 ENSDART00000147277
ENSDART00000135219
gng13a
guanine nucleotide binding protein (G protein), gamma 13a
chr11_-_39202915 7.34 ENSDART00000105133
wnt4a
wingless-type MMTV integration site family, member 4a
chr14_+_22022441 7.33 ENSDART00000149121
clcf1
cardiotrophin-like cytokine factor 1
chr9_+_6578580 7.29 ENSDART00000061577
fhl2a
four and a half LIM domains 2a
chr21_-_11632403 7.29 ENSDART00000171708
ENSDART00000138619
ENSDART00000136308
ENSDART00000144770
cast
calpastatin
chr1_+_12231478 7.27 ENSDART00000111485
tmod1
tropomodulin 1
chr22_-_30770751 7.24 ENSDART00000172115
AL831726.2

chr19_-_35428815 7.20 ENSDART00000169006
ENSDART00000003167
ak2
adenylate kinase 2
chr21_-_44081540 7.20 ENSDART00000130833
FO704810.1

chr8_-_49207319 7.19 ENSDART00000022870
fam110a
family with sequence similarity 110, member A
chr23_-_36316352 7.18 ENSDART00000014840
nfe2
nuclear factor, erythroid 2
chr4_-_26108053 7.17 ENSDART00000066951
si:ch211-244b2.4
si:ch211-244b2.4
chr23_+_10347851 7.11 ENSDART00000127667
krt18
keratin 18
chr16_-_22194400 7.08 ENSDART00000186042
il6r
interleukin 6 receptor
chr3_-_21382491 6.98 ENSDART00000016562
itga2b
integrin, alpha 2b
chr7_-_52417060 6.98 ENSDART00000148579
myzap
myocardial zonula adherens protein
chr14_+_34501245 6.93 ENSDART00000131424
lcp2b
lymphocyte cytosolic protein 2b
chr5_-_39474235 6.92 ENSDART00000171557
antxr2a
anthrax toxin receptor 2a
chr15_+_12435975 6.89 ENSDART00000168011
tmprss4a
transmembrane protease, serine 4a
chr10_+_2742499 6.87 ENSDART00000122847
grk5
G protein-coupled receptor kinase 5
chr3_-_29870848 6.82 ENSDART00000186457
rpl3
ribosomal protein L3
chr2_-_16159491 6.78 ENSDART00000110059
vav3b
vav 3 guanine nucleotide exchange factor b
chr1_-_26702930 6.75 ENSDART00000109297
ENSDART00000152389
foxe1
forkhead box E1
chr17_-_10838434 6.75 ENSDART00000064597
lgals3b
lectin, galactoside binding soluble 3b
chr1_-_9227804 6.67 ENSDART00000190360
gng13a
guanine nucleotide binding protein (G protein), gamma 13a
chr21_-_226071 6.67 ENSDART00000160667
nup54
nucleoporin 54
chr15_-_25571865 6.65 ENSDART00000077836
mmp20b
matrix metallopeptidase 20b (enamelysin)
chr7_+_49681040 6.64 ENSDART00000176372
ENSDART00000192172
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr16_-_30885838 6.61 ENSDART00000131356
dennd3b
DENN/MADD domain containing 3b
chr24_+_11334733 6.60 ENSDART00000147552
ENSDART00000143171
si:dkey-12l12.1
si:dkey-12l12.1
chr6_-_29007493 6.57 ENSDART00000065139
gfi1ab
growth factor independent 1A transcription repressor b
chr4_-_13518381 6.55 ENSDART00000067153
ifng1-1
interferon, gamma 1-1
chr7_-_2039060 6.47 ENSDART00000173879
si:cabz01007794.1
si:cabz01007794.1
chr19_+_37118547 6.47 ENSDART00000103163
cx30.9
connexin 30.9
chr10_+_35329751 6.44 ENSDART00000148043
si:dkey-259j3.5
si:dkey-259j3.5
chr14_-_26498196 6.44 ENSDART00000054175
ENSDART00000145625
ENSDART00000183347
ENSDART00000191084
ENSDART00000191143
smad5
SMAD family member 5
chr21_-_38852860 6.43 ENSDART00000166101
tlr22
toll-like receptor 22
chr12_-_30540699 6.43 ENSDART00000167712
ENSDART00000102464
zgc:153920
zgc:153920
chr6_-_7769178 6.42 ENSDART00000191701
ENSDART00000149823
myh9a
myosin, heavy chain 9a, non-muscle
chr2_-_51700709 6.41 ENSDART00000188601
tgm1l1
transglutaminase 1 like 1
chr7_+_48761875 6.39 ENSDART00000003690
acana
aggrecan a
chr2_+_36898982 6.39 ENSDART00000084859
rabgap1l2
RAB GTPase activating protein 1-like 2
chr15_+_37412883 6.38 ENSDART00000156474
zbtb32
zinc finger and BTB domain containing 32
chr7_-_38658411 6.36 ENSDART00000109463
ENSDART00000017155
npsn
nephrosin
chr10_+_38643304 6.35 ENSDART00000067447
mmp30
matrix metallopeptidase 30
chr21_+_45685757 6.31 ENSDART00000160530
sec24a
SEC24 homolog A, COPII coat complex component
chr20_-_23852174 6.28 ENSDART00000122414
si:dkey-15j16.6
si:dkey-15j16.6
chr22_-_15578402 6.28 ENSDART00000062986
hsh2d
hematopoietic SH2 domain containing
chr25_+_29472361 6.27 ENSDART00000154857
il17rel
interleukin 17 receptor E-like
chr8_+_6576940 6.26 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr3_-_7990516 6.26 ENSDART00000167877
TRIM35 (1 of many)
si:ch211-175l6.2
chr19_+_19786117 6.21 ENSDART00000167757
ENSDART00000163546
hoxa1a
homeobox A1a
chr2_-_37862380 6.17 ENSDART00000186005
si:ch211-284o19.8
si:ch211-284o19.8
chr22_+_19264181 6.16 ENSDART00000192750
ENSDART00000137591
ENSDART00000136197
si:dkey-78l4.5
si:dkey-21e2.11
si:dkey-78l4.5
si:dkey-21e2.11
chr2_-_51719439 6.15 ENSDART00000170385
tgm1l1
transglutaminase 1 like 1
chr11_+_27347076 6.11 ENSDART00000173383
fbln2
fibulin 2
chr20_+_46216431 6.10 ENSDART00000185384
stx7l
syntaxin 7-like
chr9_-_23990416 6.10 ENSDART00000113176
col6a3
collagen, type VI, alpha 3
chr1_-_9109699 6.10 ENSDART00000147833
vap
vascular associated protein
chr7_-_3894831 6.05 ENSDART00000172921
si:dkey-88n24.11
si:dkey-88n24.11
chr3_-_7948799 6.05 ENSDART00000163714
trim35-24
tripartite motif containing 35-24
chr2_-_16159203 6.02 ENSDART00000153480
vav3b
vav 3 guanine nucleotide exchange factor b
chr23_+_35847538 6.02 ENSDART00000143935
rarga
retinoic acid receptor gamma a
chr1_-_7951002 6.01 ENSDART00000138187
si:dkey-79f11.8
si:dkey-79f11.8
chr7_+_48761646 6.01 ENSDART00000017467
acana
aggrecan a
chr21_-_28439596 6.00 ENSDART00000089980
ENSDART00000132844
rasgrp2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr3_-_48259289 5.99 ENSDART00000160717
znf750
zinc finger protein 750
chr18_+_3037998 5.98 ENSDART00000185844
ENSDART00000162657
rps3
ribosomal protein S3
chr3_-_19367081 5.96 ENSDART00000191369
s1pr5a
sphingosine-1-phosphate receptor 5a
chr19_+_4068134 5.94 ENSDART00000158285
btr26
bloodthirsty-related gene family, member 26
chr9_-_14055959 5.90 ENSDART00000146675
fer1l6
fer-1-like family member 6
chr10_+_9550419 5.90 ENSDART00000064977
si:ch211-243g18.2
si:ch211-243g18.2
chr3_-_32590164 5.88 ENSDART00000151151
tspan4b
tetraspanin 4b
chr21_+_25198637 5.86 ENSDART00000164972
si:dkey-183i3.6
si:dkey-183i3.6
chr20_-_51399133 5.86 ENSDART00000151426
si:ch73-91k6.2
si:ch73-91k6.2
chr3_+_22335030 5.85 ENSDART00000055676
zgc:103564
zgc:103564
chr5_-_23909934 5.83 ENSDART00000142516
si:ch211-135f11.1
si:ch211-135f11.1
chr17_+_5976683 5.83 ENSDART00000110276
zgc:194275
zgc:194275
chr15_-_33965440 5.80 ENSDART00000163841
lsr
lipolysis stimulated lipoprotein receptor
chr6_-_2162446 5.80 ENSDART00000171265
tgm5l
transglutaminase 5, like
chr19_+_4062101 5.79 ENSDART00000166773
btr25
bloodthirsty-related gene family, member 25
chr11_+_13524504 5.68 ENSDART00000139889
arrdc2
arrestin domain containing 2
chr6_+_45932276 5.62 ENSDART00000103491
rbp7b
retinol binding protein 7b, cellular
chr23_-_4975452 5.61 ENSDART00000105241
ENSDART00000169978
ngfa
nerve growth factor a (beta polypeptide)
chr8_+_22377936 5.60 ENSDART00000181548
si:dkey-23c22.5
si:dkey-23c22.5
chr9_-_40765868 5.56 ENSDART00000138634
abca12
ATP-binding cassette, sub-family A (ABC1), member 12
chr25_+_3104959 5.56 ENSDART00000167130
rab3il1
RAB3A interacting protein (rabin3)-like 1
chr14_+_15597049 5.56 ENSDART00000159732
si:dkey-203a12.8
si:dkey-203a12.8
chr9_-_9419704 5.55 ENSDART00000138996
si:ch211-214p13.9
si:ch211-214p13.9
chr21_+_11560153 5.55 ENSDART00000065842
cd8a
CD8a molecule
chr3_-_32958505 5.54 ENSDART00000147374
ENSDART00000136919
casp6l1
caspase 6, apoptosis-related cysteine peptidase, like 1
chr11_+_24313931 5.54 ENSDART00000017599
ENSDART00000166045
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr9_-_3496548 5.54 ENSDART00000102876
cybrd1
cytochrome b reductase 1
chr22_-_10117918 5.53 ENSDART00000177475
ENSDART00000128590
rdh5
retinol dehydrogenase 5 (11-cis/9-cis)
chr16_-_11859309 5.53 ENSDART00000145754
cxcr3.1
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr16_-_51254694 5.52 ENSDART00000148894
serpinb14
serpin peptidase inhibitor, clade B (ovalbumin), member 14
chr9_+_9296222 5.51 ENSDART00000141325
si:ch211-214p13.8
si:ch211-214p13.8
chr4_+_73224617 5.49 ENSDART00000187014
ENSDART00000165194
CABZ01021435.1

chr1_-_59360114 5.44 ENSDART00000160445
CABZ01052573.1

chr16_+_1383914 5.42 ENSDART00000185089
cers2b
ceramide synthase 2b
chr13_-_18174864 5.39 ENSDART00000079884
alox5a
arachidonate 5-lipoxygenase a

Network of associatons between targets according to the STRING database.

First level regulatory network of runx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 33.3 GO:0003210 cardiac atrium formation(GO:0003210)
5.0 20.0 GO:0006740 NADPH regeneration(GO:0006740)
4.8 19.3 GO:0015840 urea transport(GO:0015840)
3.3 10.0 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
3.2 12.8 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
3.0 9.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
2.2 6.7 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
2.2 8.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
2.1 4.3 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
2.1 23.3 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
2.1 12.4 GO:0003151 outflow tract morphogenesis(GO:0003151)
2.0 12.0 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
1.8 5.4 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
1.7 13.9 GO:0042554 superoxide anion generation(GO:0042554)
1.7 5.1 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
1.6 3.3 GO:0019730 antimicrobial humoral response(GO:0019730)
1.6 7.8 GO:0071763 nuclear membrane organization(GO:0071763)
1.4 11.1 GO:0090594 inflammatory response to wounding(GO:0090594)
1.4 5.5 GO:0010039 response to iron ion(GO:0010039)
1.4 6.8 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
1.3 4.0 GO:0035331 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
1.3 6.6 GO:0097186 amelogenesis(GO:0097186)
1.3 6.4 GO:0072104 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
1.3 14.0 GO:0050909 sensory perception of taste(GO:0050909)
1.3 8.8 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
1.3 8.8 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
1.2 25.8 GO:0018149 peptide cross-linking(GO:0018149)
1.1 4.5 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
1.1 3.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
1.1 5.5 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
1.1 3.3 GO:0007635 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
1.1 8.7 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
1.1 3.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
1.0 7.3 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
1.0 21.5 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
1.0 3.0 GO:0043388 positive regulation of DNA binding(GO:0043388)
1.0 7.0 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
1.0 2.9 GO:0007571 age-dependent general metabolic decline(GO:0007571)
1.0 2.9 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
1.0 15.2 GO:0036065 fucosylation(GO:0036065)
0.9 4.7 GO:1904105 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.9 5.5 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.9 80.0 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.9 8.1 GO:0033628 regulation of cell adhesion mediated by integrin(GO:0033628)
0.9 9.6 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.8 5.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.8 4.1 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.8 2.4 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.8 7.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.8 3.2 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.8 5.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.8 6.9 GO:1901998 toxin transport(GO:1901998)
0.8 11.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.8 15.8 GO:0030183 B cell differentiation(GO:0030183)
0.7 3.0 GO:0009265 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221) 2'-deoxyribonucleotide biosynthetic process(GO:0009265) deoxyribose phosphate biosynthetic process(GO:0046385)
0.7 7.4 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.7 7.2 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.7 5.6 GO:0048730 epidermis morphogenesis(GO:0048730)
0.7 9.6 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.7 4.7 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.7 2.7 GO:0042755 eating behavior(GO:0042755)
0.6 1.3 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.6 3.9 GO:0001955 blood vessel maturation(GO:0001955)
0.6 1.9 GO:0019556 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.6 2.5 GO:0051661 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.6 13.3 GO:0015671 oxygen transport(GO:0015671)
0.6 4.9 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.6 1.2 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.6 1.8 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.6 1.8 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.6 2.4 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898) positive regulation of lipid catabolic process(GO:0050996)
0.6 2.3 GO:0008356 asymmetric cell division(GO:0008356)
0.6 6.9 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.6 2.9 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.6 3.4 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.6 3.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.6 4.0 GO:1900117 regulation of execution phase of apoptosis(GO:1900117) negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.6 5.6 GO:2000403 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.6 1.7 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.5 3.8 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.5 7.6 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122) negative regulation of innate immune response(GO:0045824)
0.5 3.8 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.5 71.8 GO:0042742 defense response to bacterium(GO:0042742)
0.5 2.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.5 4.0 GO:0021588 cerebellum formation(GO:0021588)
0.5 6.0 GO:0097696 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.5 2.5 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.5 2.9 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.5 2.9 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.5 1.4 GO:0046833 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833)
0.5 7.2 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.5 1.9 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.5 5.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.5 2.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.5 4.1 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.5 3.2 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.5 2.3 GO:0010447 response to acidic pH(GO:0010447)
0.5 0.9 GO:0033212 iron assimilation(GO:0033212)
0.4 4.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.4 2.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.4 1.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.4 8.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 6.6 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.4 3.7 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.4 1.6 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.4 8.8 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.4 9.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.4 12.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.4 3.1 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.4 1.2 GO:0070640 vitamin D3 metabolic process(GO:0070640)
0.4 3.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.4 35.5 GO:0009617 response to bacterium(GO:0009617)
0.4 4.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.4 0.4 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.4 1.1 GO:1901052 sarcosine metabolic process(GO:1901052)
0.4 35.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.4 4.6 GO:0070527 platelet aggregation(GO:0070527)
0.4 1.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.4 1.4 GO:0070199 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.3 10.8 GO:0030199 collagen fibril organization(GO:0030199)
0.3 3.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.3 5.1 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.3 4.7 GO:0098868 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.3 2.0 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.3 15.5 GO:0007599 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.3 2.2 GO:0000730 DNA recombinase assembly(GO:0000730)
0.3 1.0 GO:0034398 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.3 1.6 GO:0006212 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
0.3 6.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 2.8 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.3 4.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.3 9.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.3 6.0 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.3 2.0 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.3 1.4 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.3 3.6 GO:0042026 protein refolding(GO:0042026)
0.3 0.8 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.3 3.0 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.3 1.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.3 1.6 GO:0070935 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967) 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.3 3.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.3 1.5 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.3 2.6 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.3 12.5 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.3 3.5 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 6.9 GO:0002377 immunoglobulin production(GO:0002377)
0.2 5.2 GO:0007210 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) serotonin receptor signaling pathway(GO:0007210)
0.2 10.7 GO:0031638 zymogen activation(GO:0031638)
0.2 6.7 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.2 0.9 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.2 6.6 GO:0002685 regulation of leukocyte migration(GO:0002685)
0.2 3.7 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 3.9 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.2 26.0 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.2 7.0 GO:0060037 pharyngeal system development(GO:0060037)
0.2 1.9 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.2 3.1 GO:0046686 response to cadmium ion(GO:0046686)
0.2 3.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.2 0.6 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.2 9.4 GO:0060348 bone development(GO:0060348)
0.2 2.2 GO:0007608 sensory perception of smell(GO:0007608)
0.2 9.1 GO:0002062 chondrocyte differentiation(GO:0002062)
0.2 3.6 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.2 2.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 1.5 GO:0051013 microtubule severing(GO:0051013)
0.2 2.3 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.2 2.8 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.2 4.8 GO:0032526 response to retinoic acid(GO:0032526)
0.2 2.0 GO:0036368 cone photoresponse recovery(GO:0036368)
0.2 4.1 GO:0007520 myoblast fusion(GO:0007520)
0.2 3.9 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.2 4.2 GO:0007634 optokinetic behavior(GO:0007634)
0.2 0.7 GO:0061055 myotome development(GO:0061055)
0.2 2.8 GO:0019835 cytolysis(GO:0019835)
0.2 10.2 GO:0043542 endothelial cell migration(GO:0043542)
0.2 3.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.2 3.3 GO:0048570 notochord morphogenesis(GO:0048570)
0.2 1.2 GO:0090497 mesenchymal cell migration(GO:0090497)
0.2 0.3 GO:0001658 ureteric bud development(GO:0001657) branching involved in ureteric bud morphogenesis(GO:0001658) mesonephros development(GO:0001823) ureteric bud morphogenesis(GO:0060675) regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164) mesonephric tubule morphogenesis(GO:0072171) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.2 4.0 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 2.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.2 2.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.2 1.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 6.5 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.2 2.8 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.2 2.9 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2 1.3 GO:0000710 meiotic mismatch repair(GO:0000710)
0.2 4.7 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 0.8 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.6 GO:0060547 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544) negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.1 7.5 GO:0001945 lymph vessel development(GO:0001945)
0.1 2.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 1.4 GO:0065005 plasma lipoprotein particle assembly(GO:0034377) protein-lipid complex assembly(GO:0065005)
0.1 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 4.3 GO:0019915 lipid storage(GO:0019915)
0.1 1.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 1.0 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 2.7 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 1.4 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 0.9 GO:0006501 macromitophagy(GO:0000423) C-terminal protein lipidation(GO:0006501)
0.1 7.3 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 1.5 GO:0043171 peptide catabolic process(GO:0043171)
0.1 1.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 3.2 GO:0006956 complement activation(GO:0006956) protein activation cascade(GO:0072376)
0.1 7.7 GO:0002768 immune response-regulating cell surface receptor signaling pathway(GO:0002768)
0.1 1.9 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 3.0 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 1.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.7 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 2.5 GO:0048264 determination of ventral identity(GO:0048264)
0.1 1.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.9 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.1 2.0 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 7.3 GO:0007492 endoderm development(GO:0007492)
0.1 0.9 GO:0044211 CTP salvage(GO:0044211)
0.1 0.5 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.1 0.4 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 6.7 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.1 2.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.2 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.1 5.2 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.1 1.0 GO:0050975 sensory perception of touch(GO:0050975)
0.1 1.4 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.5 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.1 0.6 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.1 1.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 1.4 GO:0009409 response to cold(GO:0009409)
0.1 1.7 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 1.2 GO:0001573 ganglioside metabolic process(GO:0001573) ganglioside catabolic process(GO:0006689)
0.1 0.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 6.8 GO:0031101 fin regeneration(GO:0031101)
0.1 6.6 GO:0048278 vesicle docking(GO:0048278)
0.1 14.2 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1 0.7 GO:0030325 adrenal gland development(GO:0030325)
0.1 0.5 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.1 0.4 GO:0070586 cell-cell adhesion involved in gastrulation(GO:0070586) regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1 2.5 GO:0045089 positive regulation of defense response(GO:0031349) positive regulation of innate immune response(GO:0045089)
0.1 0.7 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.1 2.0 GO:0016925 protein sumoylation(GO:0016925)
0.1 2.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 1.6 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 13.5 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 0.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.3 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 1.3 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 6.0 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.1 3.4 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 0.9 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 2.3 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.1 1.1 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.1 1.0 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 1.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 0.6 GO:0042493 response to drug(GO:0042493)
0.1 0.7 GO:0046847 filopodium assembly(GO:0046847)
0.1 0.5 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 1.0 GO:0007032 endosome organization(GO:0007032)
0.1 1.9 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.1 1.9 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 2.1 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 1.7 GO:0006909 phagocytosis(GO:0006909)
0.0 2.2 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.7 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 1.1 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.4 GO:0009204 nucleoside triphosphate catabolic process(GO:0009143) deoxyribonucleoside triphosphate catabolic process(GO:0009204)
0.0 2.9 GO:0032273 positive regulation of protein polymerization(GO:0032273)
0.0 8.7 GO:0060047 heart contraction(GO:0060047)
0.0 1.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.6 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.3 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 2.1 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 0.5 GO:0006000 fructose metabolic process(GO:0006000) fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.8 GO:0051923 sulfation(GO:0051923)
0.0 1.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:1904590 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.0 1.4 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.3 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.4 GO:0051984 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of chromosome segregation(GO:0051984) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.4 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.1 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 1.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.4 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 2.0 GO:0050657 nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236)
0.0 1.2 GO:0060326 cell chemotaxis(GO:0060326)
0.0 0.8 GO:0008272 sulfate transport(GO:0008272)
0.0 2.0 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 0.6 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 1.2 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 1.9 GO:0071559 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 1.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 2.0 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 2.1 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.9 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.4 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.5 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.1 GO:0031646 positive regulation of neurological system process(GO:0031646)
0.0 0.8 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.8 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 0.1 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 1.8 GO:0030218 erythrocyte differentiation(GO:0030218) erythrocyte homeostasis(GO:0034101)
0.0 1.1 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 1.5 GO:0021782 glial cell development(GO:0021782)
0.0 2.8 GO:0006887 exocytosis(GO:0006887)
0.0 1.1 GO:0016485 protein processing(GO:0016485)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 13.9 GO:0043020 NADPH oxidase complex(GO:0043020)
1.4 5.6 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
1.4 5.6 GO:0019815 B cell receptor complex(GO:0019815)
1.3 3.9 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
1.3 7.6 GO:0042612 MHC class I protein complex(GO:0042612)
1.1 7.4 GO:0016234 inclusion body(GO:0016234)
1.0 2.9 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.9 8.5 GO:0070938 contractile ring(GO:0070938)
0.9 13.7 GO:0070187 telosome(GO:0070187)
0.9 6.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.9 9.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.8 6.8 GO:0001772 immunological synapse(GO:0001772)
0.8 3.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.8 2.4 GO:0044316 cone cell pedicle(GO:0044316)
0.8 7.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.7 2.2 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.7 4.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.7 8.6 GO:0005922 connexon complex(GO:0005922)
0.6 5.5 GO:0031526 brush border membrane(GO:0031526)
0.5 2.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.5 2.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.5 3.2 GO:0005784 Sec61 translocon complex(GO:0005784)
0.5 1.0 GO:0043614 multi-eIF complex(GO:0043614)
0.5 2.1 GO:0061702 inflammasome complex(GO:0061702)
0.4 1.3 GO:0034709 methylosome(GO:0034709)
0.4 1.3 GO:0032301 MutSalpha complex(GO:0032301)
0.4 2.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.4 1.7 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.4 1.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.4 11.1 GO:0005839 proteasome core complex(GO:0005839)
0.4 2.8 GO:0000784 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.4 24.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 1.5 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.4 2.2 GO:0071986 Ragulator complex(GO:0071986)
0.4 1.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.3 1.4 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.3 17.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 6.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.3 2.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 65.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.3 1.1 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.3 15.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.3 0.8 GO:0030689 Noc complex(GO:0030689)
0.3 4.0 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 1.0 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 3.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 9.5 GO:0005795 Golgi stack(GO:0005795)
0.2 1.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 10.8 GO:0022626 cytosolic ribosome(GO:0022626)
0.2 11.5 GO:0005811 lipid particle(GO:0005811)
0.2 1.4 GO:0034518 RNA cap binding complex(GO:0034518)
0.2 11.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 19.3 GO:0005581 collagen trimer(GO:0005581)
0.2 3.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 8.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 2.8 GO:0005579 membrane attack complex(GO:0005579)
0.2 2.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.2 3.0 GO:0042555 MCM complex(GO:0042555)
0.2 1.6 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 4.1 GO:0035371 microtubule plus-end(GO:0035371)
0.2 2.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 162.3 GO:0005615 extracellular space(GO:0005615)
0.1 13.5 GO:0030018 Z disc(GO:0030018)
0.1 1.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 6.8 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.1 1.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 7.3 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 21.1 GO:0031012 extracellular matrix(GO:0031012)
0.1 1.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.7 GO:0070876 SOSS complex(GO:0070876)
0.1 4.6 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 12.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 9.0 GO:0031201 SNARE complex(GO:0031201)
0.1 9.8 GO:0005882 intermediate filament(GO:0005882)
0.1 3.0 GO:0043186 P granule(GO:0043186)
0.1 5.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 15.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 1.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.0 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 7.5 GO:0005764 lysosome(GO:0005764)
0.1 1.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 1.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.1 GO:0036038 MKS complex(GO:0036038)
0.1 2.1 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 2.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 2.9 GO:0016592 mediator complex(GO:0016592)
0.1 7.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 5.7 GO:0000786 nucleosome(GO:0000786)
0.1 3.1 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 1.3 GO:0000795 synaptonemal complex(GO:0000795)
0.1 6.4 GO:0016459 myosin complex(GO:0016459)
0.1 2.1 GO:0031901 early endosome membrane(GO:0031901)
0.1 9.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 5.9 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 1.1 GO:0045180 basal cortex(GO:0045180)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.5 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 1.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 1.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.4 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 13.1 GO:0005576 extracellular region(GO:0005576)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 2.9 GO:0005911 cell-cell junction(GO:0005911)
0.0 2.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 1.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.4 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.7 GO:0005770 late endosome(GO:0005770)
0.0 0.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.6 GO:0000793 condensed chromosome(GO:0000793)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 20.0 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
3.0 33.3 GO:0032036 myosin heavy chain binding(GO:0032036)
2.9 8.8 GO:0016748 succinyltransferase activity(GO:0016748)
2.6 7.8 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
2.5 9.9 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
2.3 18.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
2.2 24.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
2.1 10.3 GO:0060182 apelin receptor activity(GO:0060182)
2.1 18.5 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
1.8 5.5 GO:0000293 ferric-chelate reductase activity(GO:0000293)
1.7 1.7 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
1.5 4.6 GO:0070051 fibrinogen binding(GO:0070051)
1.5 4.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
1.4 6.8 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
1.3 7.8 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
1.3 25.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
1.3 3.9 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
1.3 15.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
1.2 2.4 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
1.1 3.3 GO:0042806 fucose binding(GO:0042806)
1.1 7.4 GO:0042834 peptidoglycan binding(GO:0042834)
1.0 3.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
1.0 7.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
1.0 4.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
1.0 9.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
1.0 11.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.0 2.9 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672)
1.0 3.9 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.9 5.4 GO:0008142 oxysterol binding(GO:0008142)
0.9 3.6 GO:0008329 lipopolysaccharide receptor activity(GO:0001875) signaling pattern recognition receptor activity(GO:0008329)
0.9 2.7 GO:0048030 disaccharide binding(GO:0048030)
0.9 9.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.9 2.6 GO:0045545 syndecan binding(GO:0045545)
0.8 17.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.8 2.5 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.8 2.4 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.8 3.2 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.8 19.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.8 9.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.7 2.2 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.7 3.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.7 2.1 GO:0046978 TAP1 binding(GO:0046978)
0.7 2.8 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.7 3.4 GO:0070573 metallodipeptidase activity(GO:0070573)
0.7 8.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.6 4.5 GO:0019809 spermidine binding(GO:0019809)
0.6 11.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.6 13.3 GO:0019825 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.6 8.6 GO:0005243 gap junction channel activity(GO:0005243)
0.6 3.0 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.6 4.7 GO:0003993 acid phosphatase activity(GO:0003993)
0.6 7.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.6 4.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.6 11.1 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.6 2.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.6 1.7 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.6 3.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.5 63.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.5 4.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 7.8 GO:0005123 death receptor binding(GO:0005123)
0.5 3.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.5 4.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.5 3.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.5 3.5 GO:0030274 LIM domain binding(GO:0030274)
0.5 2.9 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.5 21.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.5 1.9 GO:0016841 ammonia-lyase activity(GO:0016841)
0.5 2.8 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.5 1.4 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.5 15.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.5 1.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.5 1.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.4 1.3 GO:0032404 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.4 3.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.4 9.1 GO:0019894 kinesin binding(GO:0019894)
0.4 2.9 GO:0004974 leukotriene receptor activity(GO:0004974)
0.4 27.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.4 5.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.4 2.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.4 12.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.4 4.5 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.4 3.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.4 1.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.3 1.4 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.3 20.5 GO:0031072 heat shock protein binding(GO:0031072)
0.3 2.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.3 4.3 GO:0016405 CoA-ligase activity(GO:0016405)
0.3 17.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 7.3 GO:0005523 tropomyosin binding(GO:0005523)
0.3 1.3 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.3 4.9 GO:0070492 oligosaccharide binding(GO:0070492)
0.3 1.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.3 6.4 GO:0070411 I-SMAD binding(GO:0070411)
0.3 2.2 GO:0005549 odorant binding(GO:0005549)
0.3 1.6 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.3 3.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.3 2.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.3 0.9 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.3 2.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.3 2.4 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.3 2.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.3 2.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.3 10.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.3 1.1 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.3 18.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.3 3.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.3 2.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.3 5.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.3 15.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.3 18.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.3 5.0 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2 1.5 GO:0004104 cholinesterase activity(GO:0004104)
0.2 8.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 8.4 GO:0042923 neuropeptide binding(GO:0042923)
0.2 6.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 0.7 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.2 10.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 2.0 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.2 1.6 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.2 77.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.2 3.5 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
0.2 0.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 5.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 2.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 15.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 1.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 2.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 1.2 GO:0015616 DNA translocase activity(GO:0015616)
0.2 1.4 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 0.9 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.2 0.9 GO:0031769 glucagon receptor binding(GO:0031769)
0.2 3.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.2 35.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 2.3 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.2 2.8 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 1.6 GO:0008494 translation activator activity(GO:0008494)
0.2 4.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 2.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 36.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 2.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 1.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 3.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 3.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.2 23.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 0.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.5 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.2 18.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 2.0 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 0.8 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.2 3.8 GO:0005112 Notch binding(GO:0005112)
0.1 1.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 2.8 GO:0004875 complement receptor activity(GO:0004875)
0.1 5.7 GO:0005109 frizzled binding(GO:0005109)
0.1 13.3 GO:0020037 heme binding(GO:0020037)
0.1 0.5 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 4.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 10.1 GO:0019905 syntaxin binding(GO:0019905)
0.1 2.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 1.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 3.1 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.4 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.1 2.2 GO:0031267 small GTPase binding(GO:0031267)
0.1 6.8 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 0.9 GO:0004849 uridine kinase activity(GO:0004849)
0.1 12.0 GO:0005125 cytokine activity(GO:0005125)
0.1 2.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 7.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.9 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.6 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.5 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 1.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 3.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 1.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 1.9 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 1.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 5.5 GO:0005319 lipid transporter activity(GO:0005319)
0.1 0.7 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.3 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.1 6.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.1 1.4 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 2.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 4.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.1 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 3.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 1.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.5 GO:0016936 galactoside binding(GO:0016936)
0.1 2.0 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.1 0.3 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 5.8 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.1 4.1 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.5 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0031386 protein tag(GO:0031386)
0.0 1.5 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.5 GO:0008443 phosphofructokinase activity(GO:0008443)
0.0 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.8 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 20.9 GO:0046983 protein dimerization activity(GO:0046983)
0.0 5.2 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.3 GO:0032977 membrane insertase activity(GO:0032977)
0.0 1.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.7 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 11.6 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 1.0 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.7 8.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.7 13.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.7 6.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.7 17.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.6 16.2 PID RAS PATHWAY Regulation of Ras family activation
0.6 17.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.5 4.2 PID IL5 PATHWAY IL5-mediated signaling events
0.5 6.4 PID ALK2 PATHWAY ALK2 signaling events
0.5 14.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.5 2.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.4 2.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.4 3.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.4 6.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 3.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 1.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.3 2.0 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.3 5.2 PID IL23 PATHWAY IL23-mediated signaling events
0.3 6.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.3 13.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 13.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.3 8.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.3 4.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.3 2.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.3 39.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 10.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.3 5.2 PID ARF6 PATHWAY Arf6 signaling events
0.3 5.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 3.5 PID EPO PATHWAY EPO signaling pathway
0.2 2.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 2.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 2.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 3.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 3.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 30.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.2 2.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 4.6 PID TNF PATHWAY TNF receptor signaling pathway
0.2 7.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 26.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 1.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.2 2.0 PID BCR 5PATHWAY BCR signaling pathway
0.1 3.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 4.6 PID ATR PATHWAY ATR signaling pathway
0.1 4.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 0.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 1.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 1.1 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID SHP2 PATHWAY SHP2 signaling
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 2.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.2 PID BARD1 PATHWAY BARD1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 23.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
1.5 7.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.9 4.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.8 6.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.8 15.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.7 7.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.7 9.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.7 5.5 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.7 6.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.6 2.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.6 6.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.6 8.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.6 10.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.5 3.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.5 6.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.5 9.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.5 6.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.5 5.9 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.5 1.9 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.5 7.0 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.5 5.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.4 3.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4 3.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.4 2.0 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.4 8.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3 15.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.3 35.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 3.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 0.9 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.3 2.9 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.3 2.3 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.3 13.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 3.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 1.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3 3.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 1.6 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.3 7.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 2.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 4.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 8.5 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.2 3.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 2.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 2.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 1.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 1.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 1.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 4.4 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.1 3.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 1.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 2.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 0.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 10.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 4.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.2 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.4 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 4.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 1.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.9 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.1 2.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 3.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 3.3 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 1.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 3.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.2 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.7 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.8 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.9 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events