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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for runx2a+runx2b

Z-value: 1.43

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Transcription factors associated with runx2a+runx2b

Gene Symbol Gene ID Gene Info
runx2a
ENSDARG00000040261 RUNX family transcription factor 2a
runx2b
ENSDARG00000059233 RUNX family transcription factor 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
runx2bdr11_v1_chr20_-_44055095_440551230.672.1e-13Click!
runx2adr11_v1_chr17_+_5351922_53519220.188.3e-02Click!

Activity profile of runx2a+runx2b motif

Sorted Z-values of runx2a+runx2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr24_+_11334733 20.62 ENSDART00000147552
ENSDART00000143171
si:dkey-12l12.1
si:dkey-12l12.1
chr16_+_11724230 17.28 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr5_-_23277939 17.04 ENSDART00000003514
plp1b
proteolipid protein 1b
chr10_-_15128771 15.95 ENSDART00000101261
spp1
secreted phosphoprotein 1
chr7_+_25858380 14.80 ENSDART00000148780
ENSDART00000079218
mtmr1a
myotubularin related protein 1a
chr19_+_30633453 14.07 ENSDART00000052124
fam49al
family with sequence similarity 49, member A-like
chr2_-_44282796 12.74 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
mpz
myelin protein zero
chr24_-_4973765 12.06 ENSDART00000127597
zic1
zic family member 1 (odd-paired homolog, Drosophila)
chr5_-_23277385 11.76 ENSDART00000134982
plp1b
proteolipid protein 1b
chr20_-_14054083 11.13 ENSDART00000009549
rhag
Rh associated glycoprotein
chr23_-_15878879 11.00 ENSDART00000010119
eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr2_-_44283554 10.83 ENSDART00000184684
mpz
myelin protein zero
chr2_-_44280061 10.60 ENSDART00000136818
mpz
myelin protein zero
chr13_+_27316934 10.25 ENSDART00000164533
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr13_+_7292061 9.99 ENSDART00000179504
CABZ01072077.1
Danio rerio neuroblast differentiation-associated protein AHNAK-like (LOC795051), mRNA.
chr13_+_27316632 9.78 ENSDART00000016121
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr3_+_28576173 9.78 ENSDART00000151189
sept12
septin 12
chr15_+_29088426 8.35 ENSDART00000187290
si:ch211-137a8.4
si:ch211-137a8.4
chr3_-_22212764 7.82 ENSDART00000155490
maptb
microtubule-associated protein tau b
chr25_+_4751879 7.70 ENSDART00000169465
si:zfos-2372e4.1
si:zfos-2372e4.1
chr22_-_33679277 7.57 ENSDART00000169948
FO904977.1

chr9_+_42066030 7.45 ENSDART00000185311
ENSDART00000015267
pcbp3
poly(rC) binding protein 3
chr25_+_34984333 7.34 ENSDART00000154760
ccdc136b
coiled-coil domain containing 136b
chr9_-_40765868 7.27 ENSDART00000138634
abca12
ATP-binding cassette, sub-family A (ABC1), member 12
chr7_-_12065668 7.25 ENSDART00000101537
mex3b
mex-3 RNA binding family member B
chr20_-_30035326 7.16 ENSDART00000141068
sox11b
SRY (sex determining region Y)-box 11b
chr16_+_31853919 7.14 ENSDART00000133886
atn1
atrophin 1
chr15_+_6117502 7.08 ENSDART00000188293
PCP4 (1 of many)
Purkinje cell protein 4
chr1_+_15137901 7.07 ENSDART00000111475
pcdh7a
protocadherin 7a
chr14_+_38786298 6.86 ENSDART00000164440
si:ch211-195b11.3
si:ch211-195b11.3
chr7_-_2039060 6.82 ENSDART00000173879
si:cabz01007794.1
si:cabz01007794.1
chr23_+_27789795 6.74 ENSDART00000141458
kmt2d
lysine (K)-specific methyltransferase 2D
chr8_+_36803415 6.73 ENSDART00000111680
iqsec2b
IQ motif and Sec7 domain 2b
chr4_-_2525916 6.63 ENSDART00000134123
ENSDART00000132581
ENSDART00000019508
csrp2
cysteine and glycine-rich protein 2
chr5_-_32445835 6.61 ENSDART00000170919
ncs1a
neuronal calcium sensor 1a
chr14_+_34514336 6.60 ENSDART00000024440
foxi3b
forkhead box I3b
chr7_-_38633867 6.41 ENSDART00000137424
c1qtnf4
C1q and TNF related 4
chr15_-_24869826 6.26 ENSDART00000127047
tusc5a
tumor suppressor candidate 5a
chr19_+_37857936 6.26 ENSDART00000189289
nxph1
neurexophilin 1
chr11_-_27057572 6.22 ENSDART00000043091
iqsec1b
IQ motif and Sec7 domain 1b
chr17_+_19630272 6.15 ENSDART00000104895
rgs7a
regulator of G protein signaling 7a
chr23_-_27822920 6.08 ENSDART00000023094
acvr1ba
activin A receptor type 1Ba
chr13_-_10261383 5.98 ENSDART00000080808
six3a
SIX homeobox 3a
chr2_+_36898982 5.97 ENSDART00000084859
rabgap1l2
RAB GTPase activating protein 1-like 2
chr7_+_46368520 5.97 ENSDART00000192821
znf536
zinc finger protein 536
chr1_-_8428736 5.96 ENSDART00000138435
ENSDART00000121823
syngr3b
synaptogyrin 3b
chr16_+_50741154 5.80 ENSDART00000101627
IGLON5
zgc:110372
chr21_-_35324091 5.79 ENSDART00000185042
ublcp1
ubiquitin-like domain containing CTD phosphatase 1
chr2_-_22286828 5.75 ENSDART00000168653
fam110b
family with sequence similarity 110, member B
chr7_-_33829824 5.70 ENSDART00000074729
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr3_+_37197686 5.70 ENSDART00000151144
fmnl1a
formin-like 1a
chr6_-_12314475 5.69 ENSDART00000156898
ENSDART00000157058
si:dkey-276j7.1
si:dkey-276j7.1
chr11_+_24703108 5.62 ENSDART00000159173
gpr25
G protein-coupled receptor 25
chr23_-_29376859 5.59 ENSDART00000146411
sst6
somatostatin 6
chr2_-_40135942 5.55 ENSDART00000176951
ENSDART00000098632
ENSDART00000148563
ENSDART00000149895
epha4a
eph receptor A4a
chr1_+_49266886 5.52 ENSDART00000137179
caly
calcyon neuron-specific vesicular protein
chr4_+_11375894 5.47 ENSDART00000190471
ENSDART00000143963
pcloa
piccolo presynaptic cytomatrix protein a
chr21_-_26495700 5.43 ENSDART00000109379
cd248b
CD248 molecule, endosialin b
chr16_-_32672883 5.41 ENSDART00000124515
ENSDART00000190920
ENSDART00000188776
pnisr
PNN-interacting serine/arginine-rich protein
chr23_-_36724575 5.29 ENSDART00000159560
agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr6_+_13806466 5.28 ENSDART00000043522
tmem198b
transmembrane protein 198b
chr18_-_41375120 5.20 ENSDART00000098673
ptx3a
pentraxin 3, long a
chr5_-_52277643 5.01 ENSDART00000010757
rgmb
repulsive guidance molecule family member b
chr16_+_32995882 4.99 ENSDART00000170157
prss35
protease, serine, 35
chr8_-_17067364 4.98 ENSDART00000132687
rab3c
RAB3C, member RAS oncogene family
chr21_+_25068215 4.95 ENSDART00000167523
ENSDART00000189259
dixdc1b
DIX domain containing 1b
chr7_+_38770167 4.95 ENSDART00000190827
arhgap1
Rho GTPase activating protein 1
chr5_+_23597144 4.94 ENSDART00000143929
ENSDART00000142420
ENSDART00000032909
kat5b
K(lysine) acetyltransferase 5b
chr6_+_23810529 4.85 ENSDART00000166921
glulb
glutamate-ammonia ligase (glutamine synthase) b
chr10_+_21797276 4.84 ENSDART00000169105
pcdh1g29
protocadherin 1 gamma 29
chr19_+_5146460 4.83 ENSDART00000150740
si:dkey-89b17.4
si:dkey-89b17.4
chr2_-_31936966 4.80 ENSDART00000169484
ENSDART00000192492
ENSDART00000027689
amph
amphiphysin
chr22_-_10459880 4.78 ENSDART00000064801
ogn
osteoglycin
chr14_-_46616487 4.71 ENSDART00000105417
ENSDART00000166550
ENSDART00000105418
prom1a
prominin 1a
chr16_-_9869056 4.70 ENSDART00000149312
ncalda
neurocalcin delta a
chr11_+_24994705 4.70 ENSDART00000129211
zgc:92107
zgc:92107
chr22_+_9871238 4.69 ENSDART00000141085
ENSDART00000105939
si:dkey-253d23.4
si:dkey-253d23.4
chr19_+_40350468 4.67 ENSDART00000087444
hepacam2
HEPACAM family member 2
chr4_-_8882572 4.67 ENSDART00000190060
mpped1
metallophosphoesterase domain containing 1
chr1_-_26702930 4.65 ENSDART00000109297
ENSDART00000152389
foxe1
forkhead box E1
chr6_+_38381957 4.61 ENSDART00000087300
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr21_+_13387965 4.61 ENSDART00000134347
zgc:113162
zgc:113162
chr10_-_17103651 4.61 ENSDART00000108959
RNF208
ring finger protein 208
chr13_-_29424454 4.57 ENSDART00000026765
slc18a3a
solute carrier family 18 (vesicular acetylcholine transporter), member 3a
chr9_+_35860975 4.55 ENSDART00000134447
rcan1a
regulator of calcineurin 1a
chr4_+_17336557 4.55 ENSDART00000111650
pmch
pro-melanin-concentrating hormone
chr21_+_15824182 4.51 ENSDART00000065779
gnrh2
gonadotropin-releasing hormone 2
chr7_-_40993456 4.49 ENSDART00000031700
en2a
engrailed homeobox 2a
chr5_-_6377865 4.47 ENSDART00000031775
zgc:73226
zgc:73226
chr7_+_31130667 4.44 ENSDART00000173937
tjp1a
tight junction protein 1a
chr25_-_35996141 4.41 ENSDART00000149074
sall1b
spalt-like transcription factor 1b
chr7_-_18656069 4.37 ENSDART00000021559
coro1b
coronin, actin binding protein, 1B
chr19_+_16222618 4.36 ENSDART00000137189
ENSDART00000169246
ENSDART00000190583
ENSDART00000189521
ptprua
protein tyrosine phosphatase, receptor type, U, a
chr13_+_25433774 4.31 ENSDART00000141255
si:dkey-51a16.9
si:dkey-51a16.9
chr19_-_9867001 4.29 ENSDART00000091695
cacng7a
calcium channel, voltage-dependent, gamma subunit 7a
chr25_+_21324588 4.27 ENSDART00000151842
lrrn3a
leucine rich repeat neuronal 3a
chr5_+_13373593 4.27 ENSDART00000051668
ENSDART00000183883
ccl19a.2
chemokine (C-C motif) ligand 19a, tandem duplicate 2
chr18_-_40508528 4.25 ENSDART00000185249
chrna5
cholinergic receptor, nicotinic, alpha 5
chr7_+_31051603 4.24 ENSDART00000108721
tjp1a
tight junction protein 1a
chr1_-_58064738 4.21 ENSDART00000073778
caspb
caspase b
chr13_+_11440389 4.19 ENSDART00000186463
zbtb18
zinc finger and BTB domain containing 18
chr3_+_49021079 4.19 ENSDART00000162012
zgc:163083
zgc:163083
chr3_+_54168007 4.18 ENSDART00000109894
olfm2a
olfactomedin 2a
chr16_-_22863348 4.16 ENSDART00000147609
shc1
SHC (Src homology 2 domain containing) transforming protein 1
chr3_+_36160979 4.14 ENSDART00000038525
si:ch211-234h8.7
si:ch211-234h8.7
chr13_-_23095006 4.13 ENSDART00000089242
kif1bp
kif1 binding protein
chr11_+_25139495 4.12 ENSDART00000168368
si:ch211-25d12.7
si:ch211-25d12.7
chr10_-_7974155 4.12 ENSDART00000147368
ENSDART00000075524
osbp2
oxysterol binding protein 2
chr20_+_5564042 4.11 ENSDART00000090934
ENSDART00000127050
nrxn3b
neurexin 3b
chr3_+_30922947 4.08 ENSDART00000184060
cldni
claudin i
chr22_+_21255860 4.06 ENSDART00000134893
cpamd8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr15_-_12545683 4.00 ENSDART00000162807
scn2b
sodium channel, voltage-gated, type II, beta
chr6_+_29860776 3.99 ENSDART00000028406
dlg1
discs, large homolog 1 (Drosophila)
chr12_+_32159272 3.98 ENSDART00000153167
hlfb
hepatic leukemia factor b
chr21_+_21309164 3.97 ENSDART00000132174
si:ch211-191j22.8
si:ch211-191j22.8
chr2_+_12255568 3.93 ENSDART00000184164
ENSDART00000013454
prtfdc1
phosphoribosyl transferase domain containing 1
chr8_+_21353878 3.92 ENSDART00000056420
alas2
aminolevulinate, delta-, synthase 2
chr2_+_22694382 3.90 ENSDART00000139196
kif1ab
kinesin family member 1Ab
chr10_+_17088261 3.90 ENSDART00000132103
si:dkey-106l3.7
si:dkey-106l3.7
chr3_+_15271943 3.88 ENSDART00000141752
asphd1
aspartate beta-hydroxylase domain containing 1
chr7_+_63325819 3.87 ENSDART00000085612
ENSDART00000161436
pcdh7b
protocadherin 7b
chr15_-_34214440 3.82 ENSDART00000167052
etv1
ets variant 1
chr2_-_50298337 3.82 ENSDART00000155125
cntnap2b
contactin associated protein like 2b
chr1_+_41854298 3.82 ENSDART00000192672
smox
spermine oxidase
chr17_-_33714636 3.81 ENSDART00000188500
DNAL1
si:dkey-84k17.3
chr5_-_28606916 3.79 ENSDART00000026107
ENSDART00000137717
tnc
tenascin C
chr14_-_14746767 3.79 ENSDART00000183755
ENSDART00000190938
ogt.1
O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
chr21_-_13672195 3.78 ENSDART00000146717
clic3
chloride intracellular channel 3
chr18_+_35742838 3.78 ENSDART00000088504
ENSDART00000140386
rasgrp4
RAS guanyl releasing protein 4
chr16_+_25809235 3.74 ENSDART00000181196
irgq1
immunity-related GTPase family, q1
chr24_-_15131831 3.68 ENSDART00000028410
cd226
CD226 molecule
chr5_+_62374092 3.68 ENSDART00000082965
CU928117.1

chr11_-_30630628 3.67 ENSDART00000103265
zgc:158773
zgc:158773
chr2_+_24722771 3.61 ENSDART00000147207
pik3r2
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
chr25_+_19954576 3.58 ENSDART00000149335
kcna1a
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr21_-_42100471 3.55 ENSDART00000166148
gabra1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr19_-_3482138 3.54 ENSDART00000168139
hivep1
human immunodeficiency virus type I enhancer binding protein 1
chr19_-_37154436 3.53 ENSDART00000103155
cx39.4
connexin 39.4
chr15_+_39977461 3.53 ENSDART00000063786
cab39
calcium binding protein 39
chr9_-_37749973 3.53 ENSDART00000087663
sema5ba
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba
chr15_+_25489406 3.51 ENSDART00000162482
zgc:152863
zgc:152863
chr23_-_7799184 3.51 ENSDART00000190946
ENSDART00000165427
myt1b
myelin transcription factor 1b
chr22_+_20195280 3.51 ENSDART00000088603
ENSDART00000135692
si:dkey-110c1.7
si:dkey-110c1.7
chr2_-_16159491 3.50 ENSDART00000110059
vav3b
vav 3 guanine nucleotide exchange factor b
chr2_+_31948352 3.48 ENSDART00000192611
ankhb
ANKH inorganic pyrophosphate transport regulator b
chr21_+_21201346 3.47 ENSDART00000142961
rictorb
RPTOR independent companion of MTOR, complex 2b
chr13_+_40019001 3.44 ENSDART00000158820
golga7bb
golgin A7 family, member Bb
chr20_-_35246150 3.42 ENSDART00000090549
fzd3a
frizzled class receptor 3a
chr11_-_42918971 3.40 ENSDART00000052912
pcdh20
protocadherin 20
chr19_+_42693855 3.40 ENSDART00000136873
clasp2
cytoplasmic linker associated protein 2
chr18_+_17959681 3.31 ENSDART00000142700
znf423
zinc finger protein 423
chr13_+_17468161 3.31 ENSDART00000008906
znf503
zinc finger protein 503
chr3_-_36440705 3.31 ENSDART00000162875
rogdi
rogdi homolog (Drosophila)
chr4_+_20255160 3.26 ENSDART00000188658
lrtm2a
leucine-rich repeats and transmembrane domains 2a
chr8_-_39859688 3.26 ENSDART00000019907
unc119.1
unc-119 homolog 1
chr8_+_25359394 3.25 ENSDART00000111248
si:dkey-183p4.10
si:dkey-183p4.10
chr8_+_14778292 3.23 ENSDART00000089971
cacna1ea
calcium channel, voltage-dependent, R type, alpha 1E subunit a
chr10_-_20453995 3.23 ENSDART00000168541
ENSDART00000164072
si:ch211-113d22.2
si:ch211-113d22.2
chr10_-_25769334 3.19 ENSDART00000134176
postna
periostin, osteoblast specific factor a
chr23_+_36653376 3.18 ENSDART00000053189
gpr182
G protein-coupled receptor 182
chr15_+_19838458 3.18 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr14_-_14566417 3.17 ENSDART00000159056
si:dkey-27i16.2
si:dkey-27i16.2
chr23_+_28582865 3.13 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr3_+_50310684 3.13 ENSDART00000112152
gas7a
growth arrest-specific 7a
chr25_+_20119466 3.12 ENSDART00000104304
bpgm
2,3-bisphosphoglycerate mutase
chr7_+_65876335 3.11 ENSDART00000150143
tead1b
TEA domain family member 1b
chr16_+_29043813 3.11 ENSDART00000122681
nes
nestin
chr17_+_13031497 3.10 ENSDART00000115208
fbxo33
F-box protein 33
chr25_+_14109626 3.09 ENSDART00000109883
actc1c
actin, alpha, cardiac muscle 1c
chr6_-_16394528 3.07 ENSDART00000089445
agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr1_-_30689004 3.07 ENSDART00000018827
dachc
dachshund c
chr18_+_18612388 3.06 ENSDART00000186455
st3gal2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr1_+_54650048 3.06 ENSDART00000141207
si:ch211-202h22.7
si:ch211-202h22.7
chr12_+_20336070 3.04 ENSDART00000066385
zgc:163057
zgc:163057
chr6_-_24103666 3.04 ENSDART00000164915
scinla
scinderin like a
chr17_-_46457622 3.01 ENSDART00000130215
TMEM179 (1 of many)
transmembrane protein 179
chr20_+_38285671 2.98 ENSDART00000061432
ccl38a.4
chemokine (C-C motif) ligand 38, duplicate 4
chr21_+_34992550 2.97 ENSDART00000109041
ENSDART00000135400
tmprss15
transmembrane protease, serine 15
chr6_-_18121075 2.97 ENSDART00000171072
SEC14L1
si:dkey-237i9.1
chr16_+_19033554 2.97 ENSDART00000182430
rapgef5b
Rap guanine nucleotide exchange factor (GEF) 5b
chr14_-_8795081 2.96 ENSDART00000106671
tgfb2l
transforming growth factor, beta 2, like
chr7_-_71829865 2.96 ENSDART00000168754
cacnb2a
calcium channel, voltage-dependent, beta 2a
chr12_-_3903886 2.96 ENSDART00000184214
ENSDART00000041082
gdpd3b
glycerophosphodiester phosphodiesterase domain containing 3b
chr24_-_12745222 2.91 ENSDART00000151836
si:ch211-196f5.9
si:ch211-196f5.9
chr10_+_26515946 2.91 ENSDART00000134276
synj1
synaptojanin 1
chr3_-_50277959 2.90 ENSDART00000082773
ENSDART00000139524
arl16
ADP-ribosylation factor-like 16
chr14_-_2163454 2.89 ENSDART00000160123
ENSDART00000169653
pcdh2ab9
pcdh2ac
protocadherin 2 alpha b 9
protocadherin 2 alpha c
chr24_-_27419198 2.88 ENSDART00000141124
ccl34b.4
chemokine (C-C motif) ligand 34b, duplicate 4
chr7_-_48665305 2.88 ENSDART00000190507
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr6_+_54142311 2.85 ENSDART00000154115
hmga1b
high mobility group AT-hook 1b
chr9_-_28867562 2.83 ENSDART00000189597
ENSDART00000060321
zgc:91818
zgc:91818
chr15_+_17446796 2.82 ENSDART00000157189
snx19b
sorting nexin 19b
chr25_-_2081371 2.80 ENSDART00000104915
ENSDART00000156925
wnt7bb
wingless-type MMTV integration site family, member 7Bb
chr21_+_30351256 2.80 ENSDART00000078341
foxi3a
forkhead box I3a
chr24_-_21923930 2.79 ENSDART00000131944
tagln3b
transgelin 3b
chr18_+_49969568 2.78 ENSDART00000126916
mob2b
MOB kinase activator 2b
chr16_+_50006145 2.77 ENSDART00000049375
ube2e2
ubiquitin-conjugating enzyme E2E 2
chr16_+_11483811 2.76 ENSDART00000169012
ENSDART00000173042
grik5
glutamate receptor, ionotropic, kainate 5
chr9_+_38883388 2.75 ENSDART00000135902
map2
microtubule-associated protein 2
chr5_-_28625515 2.74 ENSDART00000190782
ENSDART00000179736
ENSDART00000131729
tnc
tenascin C

Network of associatons between targets according to the STRING database.

First level regulatory network of runx2a+runx2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 11.1 GO:0015840 urea transport(GO:0015840)
2.3 9.4 GO:0009957 epidermal cell fate specification(GO:0009957)
2.2 6.5 GO:0014814 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
1.9 5.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
1.7 12.1 GO:0021534 cell proliferation in hindbrain(GO:0021534)
1.5 4.6 GO:0042908 xenobiotic transport(GO:0042908)
1.4 28.8 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
1.2 3.7 GO:0002858 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
1.0 1.9 GO:0051230 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.9 11.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.9 7.3 GO:0048730 epidermis morphogenesis(GO:0048730)
0.9 3.5 GO:0003322 pancreatic A cell development(GO:0003322)
0.9 7.7 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.9 2.6 GO:0048389 intermediate mesoderm development(GO:0048389)
0.8 5.6 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.8 8.7 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.8 3.1 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.8 4.7 GO:0003417 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.8 3.8 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.7 2.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.7 3.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.7 4.9 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.7 6.1 GO:0001709 cell fate determination(GO:0001709)
0.7 7.2 GO:0046548 retinal rod cell development(GO:0046548)
0.6 1.2 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.6 1.2 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.6 6.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.6 3.5 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.6 7.3 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.5 5.5 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.5 2.6 GO:0097186 amelogenesis(GO:0097186)
0.5 4.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.5 1.4 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.4 2.2 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.4 3.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.4 23.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.4 1.7 GO:1900120 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.4 18.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.4 2.9 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.4 2.0 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.4 4.8 GO:0021754 facial nucleus development(GO:0021754)
0.4 1.2 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.4 1.1 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
0.4 1.9 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.4 2.6 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.4 23.6 GO:0006414 translational elongation(GO:0006414)
0.4 4.2 GO:0035094 response to nicotine(GO:0035094)
0.4 1.1 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.3 4.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.3 1.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.3 1.3 GO:0030224 monocyte differentiation(GO:0030224)
0.3 0.9 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.3 4.6 GO:0048016 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.3 8.4 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.3 2.4 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.3 1.7 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.3 8.3 GO:0099645 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.3 3.1 GO:0038203 TORC2 signaling(GO:0038203)
0.3 0.8 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.3 3.6 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.3 1.7 GO:1990108 protein linear deubiquitination(GO:1990108)
0.3 11.2 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.3 5.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.3 2.6 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.3 1.3 GO:0039689 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.2 0.7 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.2 2.2 GO:1901998 toxin transport(GO:1901998)
0.2 2.4 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.2 0.9 GO:0015677 copper ion import(GO:0015677)
0.2 0.9 GO:0071926 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.2 17.2 GO:0060348 bone development(GO:0060348)
0.2 8.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 0.7 GO:0002188 translation reinitiation(GO:0002188)
0.2 1.8 GO:0046850 regulation of bone remodeling(GO:0046850)
0.2 4.5 GO:0034453 microtubule anchoring(GO:0034453)
0.2 0.6 GO:0090231 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.2 1.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 1.2 GO:1902267 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.2 1.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 1.0 GO:0061339 establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.2 2.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 6.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 1.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 2.0 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.2 1.6 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 0.9 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 0.7 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2 2.9 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.2 4.2 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.2 1.8 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.2 2.4 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 1.7 GO:0046661 male sex differentiation(GO:0046661)
0.2 1.9 GO:0007584 response to nutrient(GO:0007584)
0.2 3.7 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.2 3.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.7 GO:0060956 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.1 3.0 GO:0015671 oxygen transport(GO:0015671)
0.1 2.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 1.8 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798) organ maturation(GO:0048799)
0.1 5.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.5 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.8 GO:0045658 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.1 2.0 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.4 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.6 GO:0035627 ceramide transport(GO:0035627)
0.1 0.9 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 7.4 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.1 1.5 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 0.7 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.1 0.9 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 1.4 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.1 1.8 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.3 GO:0021527 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519) spinal cord association neuron differentiation(GO:0021527)
0.1 4.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 3.8 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.1 1.1 GO:0033700 phospholipid efflux(GO:0033700)
0.1 3.1 GO:0035329 hippo signaling(GO:0035329)
0.1 0.4 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.1 9.8 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.1 0.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 1.3 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 0.6 GO:1903729 regulation of plasma membrane organization(GO:1903729)
0.1 24.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.8 GO:1905066 canonical Wnt signaling pathway involved in heart development(GO:0061316) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 0.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 1.8 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 1.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 3.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.6 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.1 9.4 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.1 4.1 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 16.8 GO:0030041 actin filament polymerization(GO:0030041)
0.1 0.3 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.3 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 0.3 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 2.3 GO:0072114 pronephros morphogenesis(GO:0072114)
0.1 2.5 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.1 6.0 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.1 3.3 GO:0048596 embryonic camera-type eye morphogenesis(GO:0048596)
0.1 2.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.6 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.1 1.1 GO:0060896 neural plate anterior/posterior regionalization(GO:0021999) neural plate pattern specification(GO:0060896) neural plate regionalization(GO:0060897)
0.1 3.1 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.1 0.8 GO:0098900 regulation of action potential(GO:0098900)
0.1 0.6 GO:0010155 regulation of proton transport(GO:0010155)
0.1 3.5 GO:0021954 central nervous system neuron development(GO:0021954)
0.1 1.8 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.7 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 1.1 GO:0033344 cholesterol efflux(GO:0033344)
0.1 0.7 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 6.3 GO:0016573 histone acetylation(GO:0016573)
0.1 2.5 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.1 0.5 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.8 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 1.7 GO:0006828 manganese ion transport(GO:0006828)
0.1 0.9 GO:0060997 dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.1 4.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 2.1 GO:0021854 hypothalamus development(GO:0021854)
0.1 2.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 4.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 3.3 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.9 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 1.4 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.8 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.1 2.1 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.1 0.7 GO:0006265 DNA topological change(GO:0006265)
0.1 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 1.9 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 2.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.9 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 2.2 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 2.5 GO:0031929 TOR signaling(GO:0031929)
0.0 0.4 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 1.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 3.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.3 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.3 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 1.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 5.5 GO:0060070 canonical Wnt signaling pathway(GO:0060070)
0.0 2.3 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.5 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.9 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.7 GO:0021602 cranial nerve morphogenesis(GO:0021602)
0.0 0.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 1.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.5 GO:0070989 oxidative demethylation(GO:0070989)
0.0 0.5 GO:0007172 signal complex assembly(GO:0007172)
0.0 2.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 3.7 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.6 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 0.9 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 3.7 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 3.0 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 0.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 2.4 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.4 GO:0070527 platelet aggregation(GO:0070527)
0.0 1.5 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.8 GO:0060037 pharyngeal system development(GO:0060037)
0.0 5.7 GO:0030334 regulation of cell migration(GO:0030334)
0.0 1.8 GO:0050684 regulation of mRNA processing(GO:0050684)
0.0 2.2 GO:0007030 Golgi organization(GO:0007030)
0.0 2.1 GO:1902652 cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.0 0.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 1.8 GO:0040008 regulation of growth(GO:0040008)
0.0 1.3 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.4 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.6 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.8 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 0.3 GO:0019985 translesion synthesis(GO:0019985)
0.0 1.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.3 GO:0015780 nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.6 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 1.3 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.3 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 1.9 GO:0030509 BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0 0.9 GO:0006821 chloride transport(GO:0006821)
0.0 0.5 GO:0071599 otic vesicle development(GO:0071599)
0.0 1.4 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.9 GO:0050769 positive regulation of neurogenesis(GO:0050769)
0.0 2.7 GO:0040007 growth(GO:0040007)
0.0 1.7 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 1.0 GO:0070509 calcium ion import(GO:0070509)
0.0 0.2 GO:0019228 neuronal action potential(GO:0019228)
0.0 3.0 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.6 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.3 GO:0003205 cardiac chamber development(GO:0003205)
0.0 0.1 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.8 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 2.3 GO:0060271 cilium morphogenesis(GO:0060271)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 63.0 GO:0043209 myelin sheath(GO:0043209)
1.1 4.2 GO:0061702 inflammasome complex(GO:0061702)
0.8 3.3 GO:0043291 RAVE complex(GO:0043291)
0.7 7.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.6 8.8 GO:0048179 activin receptor complex(GO:0048179)
0.6 4.7 GO:0071914 prominosome(GO:0071914)
0.5 5.5 GO:0098982 GABA-ergic synapse(GO:0098982)
0.5 3.8 GO:0033010 paranodal junction(GO:0033010)
0.5 3.6 GO:0033270 paranode region of axon(GO:0033270)
0.5 1.9 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.4 5.3 GO:0044295 axonal growth cone(GO:0044295)
0.4 13.4 GO:0031594 neuromuscular junction(GO:0031594)
0.4 1.7 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.4 7.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.4 3.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.4 1.1 GO:0042382 paraspeckles(GO:0042382)
0.4 1.9 GO:0070390 transcription export complex 2(GO:0070390)
0.4 5.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.3 7.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 1.7 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.3 2.2 GO:0031931 TORC1 complex(GO:0031931)
0.3 6.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.3 4.9 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.3 9.8 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.3 3.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 7.9 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 3.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.2 3.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.2 0.7 GO:0031417 NatC complex(GO:0031417)
0.2 2.6 GO:0031010 ISWI-type complex(GO:0031010)
0.2 2.1 GO:0005675 holo TFIIH complex(GO:0005675)
0.2 4.3 GO:0045180 basal cortex(GO:0045180)
0.2 3.1 GO:0031932 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.2 2.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 2.7 GO:0031209 SCAR complex(GO:0031209)
0.2 0.7 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 1.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 1.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 1.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 1.4 GO:0070938 contractile ring(GO:0070938)
0.1 8.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 2.5 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.6 GO:0034657 GID complex(GO:0034657)
0.1 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 4.3 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 6.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 4.0 GO:0042734 presynaptic membrane(GO:0042734)
0.1 2.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 1.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 2.5 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 0.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 17.0 GO:0008021 synaptic vesicle(GO:0008021)
0.1 1.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.8 GO:0005685 U1 snRNP(GO:0005685)
0.1 1.0 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.9 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 7.9 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 1.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.6 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.1 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.1 6.7 GO:0016607 nuclear speck(GO:0016607)
0.1 7.4 GO:0010008 endosome membrane(GO:0010008)
0.1 0.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 1.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 6.0 GO:0005884 actin filament(GO:0005884)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 5.7 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 5.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818)
0.0 3.1 GO:0055037 recycling endosome(GO:0055037)
0.0 1.5 GO:0030027 lamellipodium(GO:0030027)
0.0 3.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.3 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.8 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 5.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.4 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 12.4 GO:0005874 microtubule(GO:0005874)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.8 GO:0005839 proteasome core complex(GO:0005839)
0.0 2.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.2 GO:0031201 SNARE complex(GO:0031201)
0.0 1.0 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 6.0 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.5 GO:0005938 cell cortex(GO:0005938)
0.0 1.2 GO:0030018 Z disc(GO:0030018)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 1.3 GO:0098791 Golgi subcompartment(GO:0098791)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 8.4 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.9 GO:0098858 actin-based cell projection(GO:0098858)
0.0 3.7 GO:0000785 chromatin(GO:0000785)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 2.9 GO:0005929 cilium(GO:0005929)
0.0 0.8 GO:0005925 focal adhesion(GO:0005925)
0.0 1.1 GO:0005912 adherens junction(GO:0005912)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 28.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.8 5.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.5 4.5 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
1.5 14.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
1.3 3.9 GO:0016748 succinyltransferase activity(GO:0016748)
1.1 5.6 GO:0060182 apelin receptor activity(GO:0060182)
1.0 4.2 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
1.0 6.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.8 3.2 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.8 4.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.8 3.8 GO:0046592 polyamine oxidase activity(GO:0046592)
0.8 4.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.7 3.5 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.7 4.9 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.6 3.8 GO:0097363 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.6 3.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.6 3.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.6 27.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.6 1.7 GO:0031701 angiotensin receptor binding(GO:0031701)
0.5 3.1 GO:0019215 intermediate filament binding(GO:0019215)
0.5 2.0 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.5 3.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.5 1.4 GO:0070336 flap-structured DNA binding(GO:0070336)
0.4 1.3 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.4 5.6 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.4 5.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.4 1.5 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.4 2.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4 1.8 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 1.4 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.3 4.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 3.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3 2.3 GO:0030274 LIM domain binding(GO:0030274)
0.3 5.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.3 2.6 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.3 8.3 GO:0042805 actinin binding(GO:0042805)
0.3 5.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.3 2.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 4.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.3 6.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3 4.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 4.6 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.3 5.3 GO:0015026 coreceptor activity(GO:0015026)
0.3 2.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 1.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 1.1 GO:0033745 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.3 2.7 GO:0017002 activin-activated receptor activity(GO:0017002)
0.3 11.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 3.5 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.3 3.0 GO:0031720 haptoglobin binding(GO:0031720)
0.2 8.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 0.9 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 2.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 3.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.2 4.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 1.1 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 0.6 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.2 4.4 GO:0051018 protein kinase A binding(GO:0051018)
0.2 3.3 GO:0048495 Roundabout binding(GO:0048495)
0.2 1.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.2 1.2 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 1.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 2.2 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.2 2.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 6.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 3.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 9.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 10.0 GO:0015485 cholesterol binding(GO:0015485)
0.2 2.0 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.2 0.9 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.2 2.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 0.7 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.2 0.7 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 2.0 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.2 2.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 1.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 3.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 5.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 4.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.9 GO:0030507 spectrin binding(GO:0030507)
0.1 1.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 6.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 1.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 0.4 GO:0070051 fibrinogen binding(GO:0070051)
0.1 2.5 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 10.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 2.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 4.2 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.1 1.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 8.6 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 4.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.0 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 1.1 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 3.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 1.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 2.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 3.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 3.5 GO:0019003 GDP binding(GO:0019003)
0.1 2.2 GO:0005112 Notch binding(GO:0005112)
0.1 3.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.9 GO:0035198 miRNA binding(GO:0035198)
0.1 3.5 GO:0005109 frizzled binding(GO:0005109)
0.1 0.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.7 GO:0005113 patched binding(GO:0005113)
0.1 0.6 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 1.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 6.8 GO:0030276 clathrin binding(GO:0030276)
0.1 26.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 1.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 25.7 GO:0003924 GTPase activity(GO:0003924)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 3.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 2.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 1.3 GO:0031267 small GTPase binding(GO:0031267)
0.1 1.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 5.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 3.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 12.1 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 1.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 9.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.7 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 2.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 2.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 3.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 6.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.4 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 2.1 GO:0044325 ion channel binding(GO:0044325)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 2.5 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.6 GO:0045159 myosin II binding(GO:0045159)
0.0 3.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 1.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 1.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.9 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.7 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 1.9 GO:0003678 DNA helicase activity(GO:0003678)
0.0 9.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0032451 demethylase activity(GO:0032451)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.9 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.6 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 1.7 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 2.1 GO:0051213 dioxygenase activity(GO:0051213)
0.0 3.2 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.9 GO:0005254 chloride channel activity(GO:0005254)
0.0 2.2 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 2.0 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 3.3 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 23.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.3 4.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 8.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.3 2.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.3 5.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.3 5.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.3 8.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 3.2 PID REELIN PATHWAY Reelin signaling pathway
0.2 4.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 6.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 3.8 PID RAS PATHWAY Regulation of Ras family activation
0.2 6.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 2.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 2.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 2.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 3.7 PID LKB1 PATHWAY LKB1 signaling events
0.1 2.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 3.6 PID BMP PATHWAY BMP receptor signaling
0.1 1.4 PID MYC PATHWAY C-MYC pathway
0.1 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 1.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 1.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 9.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 2.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID BCR 5PATHWAY BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.5 8.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.5 6.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.5 4.5 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.5 6.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.5 4.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.4 27.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.3 4.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 3.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 3.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.3 3.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.3 1.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 1.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.3 3.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 2.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.3 3.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 3.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 4.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 2.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 2.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 1.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 5.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.7 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 1.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.7 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 2.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.8 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 2.1 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 0.9 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 2.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.8 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.1 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.0 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 1.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 4.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 3.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling