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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for si:dkey-149i17.7_zic1

Z-value: 1.19

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Transcription factors associated with si:dkey-149i17.7_zic1

Gene Symbol Gene ID Gene Info
si_dkey-149i17.7
ENSDARG00000094684 si_dkey-149i17.7
zic1
ENSDARG00000015567 zic family member 1 (odd-paired homolog, Drosophila)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zic1dr11_v1_chr24_-_4973765_49737650.645.4e-12Click!
si:dkey-149i17.7dr11_v1_chr2_+_24885987_248859870.037.7e-01Click!

Activity profile of si:dkey-149i17.7_zic1 motif

Sorted Z-values of si:dkey-149i17.7_zic1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_24699985 12.53 ENSDART00000052802
calb2b
calbindin 2b
chr23_-_46217134 10.56 ENSDART00000189477
ENSDART00000168352
CABZ01102528.1

chr16_-_27640995 10.25 ENSDART00000019658
nacad
NAC alpha domain containing
chr14_-_51855047 10.18 ENSDART00000088912
cplx1
complexin 1
chr22_+_5106751 9.70 ENSDART00000138967
atcaya
ataxia, cerebellar, Cayman type a
chr13_+_27314795 9.40 ENSDART00000128726
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr24_-_3419998 9.28 ENSDART00000066839
slc35g2b
solute carrier family 35, member G2b
chr3_+_24482999 9.04 ENSDART00000059179
nptxra
neuronal pentraxin receptor a
chr25_-_29134654 8.66 ENSDART00000067066
parp6b
poly (ADP-ribose) polymerase family, member 6b
chr13_-_226393 8.62 ENSDART00000172677
rtn4b
reticulon 4b
chr8_+_8845932 8.57 ENSDART00000112028
si:ch211-180f4.1
si:ch211-180f4.1
chr18_+_49411417 8.34 ENSDART00000028944
LRFN3
zmp:0000001073
chr18_+_7345417 8.01 ENSDART00000041429
glipr1b
GLI pathogenesis-related 1b
chr21_+_3093419 7.99 ENSDART00000162520
SHC3
SHC adaptor protein 3
chr13_-_11667661 7.98 ENSDART00000102411
dctn1b
dynactin 1b
chr14_-_3031810 7.90 ENSDART00000090213
ndst1a
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a
chr13_+_7292061 7.78 ENSDART00000179504
CABZ01072077.1
Danio rerio neuroblast differentiation-associated protein AHNAK-like (LOC795051), mRNA.
chr14_-_3032016 7.72 ENSDART00000183461
ENSDART00000183035
ndst1a
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a
chr11_-_18799827 7.66 ENSDART00000185438
ENSDART00000189116
ENSDART00000180504
pfkfb2b
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr13_-_226109 7.63 ENSDART00000161705
ENSDART00000172744
ENSDART00000163902
ENSDART00000158208
rtn4b
reticulon 4b
chr17_+_5915875 7.28 ENSDART00000184179
fndc4b
fibronectin type III domain containing 4b
chr16_-_55028740 7.10 ENSDART00000156368
ENSDART00000161704
zgc:114181
zgc:114181
chr24_-_30096666 7.04 ENSDART00000183285
plppr4b
phospholipid phosphatase related 4b
chr1_+_45085194 7.01 ENSDART00000193863
si:ch211-151p13.8
si:ch211-151p13.8
chr19_+_46259619 6.99 ENSDART00000158032
grinaa
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1a (glutamate binding)
chr10_-_2526526 6.95 ENSDART00000191726
ENSDART00000192767
CU856539.1

chr18_+_5549672 6.39 ENSDART00000184970
nnt2
nicotinamide nucleotide transhydrogenase 2
chr14_+_7140997 6.28 ENSDART00000170994
ENSDART00000129898
ctsf
cathepsin F
chr6_-_13308813 6.25 ENSDART00000065372
kcnj3b
potassium inwardly-rectifying channel, subfamily J, member 3b
chr4_-_2162688 6.06 ENSDART00000148900
kcnc2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr20_-_18731268 6.00 ENSDART00000183893
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr12_-_35393211 5.79 ENSDART00000137139
camk2g1
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr19_-_32641725 5.64 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr7_-_67842997 5.56 ENSDART00000169763
pmfbp1
polyamine modulated factor 1 binding protein 1
chr23_+_44741500 5.48 ENSDART00000166421
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr3_+_54047342 5.42 ENSDART00000178486
olfm2a
olfactomedin 2a
chr12_+_48634927 5.29 ENSDART00000168441
zgc:165653
zgc:165653
chr23_+_216012 5.27 ENSDART00000181115
ENSDART00000004678
ENSDART00000190439
ENSDART00000189322
PDZD4
si:ch73-162j3.4
chr25_-_37205061 5.20 ENSDART00000155620
si:dkey-234i14.2
si:dkey-234i14.2
chr25_-_10564721 5.20 ENSDART00000154776
galn
galanin/GMAP prepropeptide
chr4_-_1324141 5.10 ENSDART00000180720
ptn
pleiotrophin
chr5_-_45651548 5.10 ENSDART00000097645
NPFFR2
neuropeptide FF receptor 2a
chr19_-_9472893 5.09 ENSDART00000045565
ENSDART00000137505
vamp1
vesicle-associated membrane protein 1
chr25_+_31264155 5.08 ENSDART00000012256
tnni2a.3
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr9_+_307863 5.05 ENSDART00000163474
stac3
SH3 and cysteine rich domain 3
chr4_-_4795205 5.04 ENSDART00000039313
zgc:162331
zgc:162331
chr16_-_13004166 5.01 ENSDART00000133735
cacng7b
calcium channel, voltage-dependent, gamma subunit 7b
chr4_-_26322834 4.96 ENSDART00000170709
ENSDART00000161687
st8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr17_+_13664442 4.75 ENSDART00000171689
lrfn5a
leucine rich repeat and fibronectin type III domain containing 5a
chr16_+_14029283 4.60 ENSDART00000146165
ENSDART00000132075
rusc1
RUN and SH3 domain containing 1
chr9_-_6208067 4.58 ENSDART00000032368
tmtops2b
teleost multiple tissue opsin 2b
chr25_-_10565006 4.45 ENSDART00000130608
ENSDART00000190212
galn
galanin/GMAP prepropeptide
chr21_+_18353703 4.44 ENSDART00000181396
ENSDART00000166359
si:ch73-287m6.1
si:ch73-287m6.1
chr6_+_29923593 4.39 ENSDART00000169687
dlg1
discs, large homolog 1 (Drosophila)
chr13_+_30912117 4.34 ENSDART00000133138
drgx
dorsal root ganglia homeobox
chr16_+_50741154 4.31 ENSDART00000101627
IGLON5
zgc:110372
chr16_+_50755133 4.31 ENSDART00000029283
IGLON5
zgc:110372
chr4_-_22671469 4.26 ENSDART00000050753
cd36
CD36 molecule (thrombospondin receptor)
chr23_+_35759843 4.07 ENSDART00000047082
gdap1l1
ganglioside induced differentiation associated protein 1-like 1
chr23_+_22267374 4.06 ENSDART00000079035
rap1gap
RAP1 GTPase activating protein
chr20_-_52846212 4.06 ENSDART00000040265
tbc1d7
TBC1 domain family, member 7
chr21_-_45588720 3.96 ENSDART00000186642
ENSDART00000189531
LO018363.2

chr10_-_41450367 3.95 ENSDART00000122682
ENSDART00000189549
cabp1b
calcium binding protein 1b
chr3_-_19899914 3.89 ENSDART00000134969
rnd2
Rho family GTPase 2
chr17_-_44584811 3.89 ENSDART00000165059
ENSDART00000165252
slc35f4
solute carrier family 35, member F4
chr7_+_22543963 3.85 ENSDART00000101528
chrnb1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr14_+_36521553 3.78 ENSDART00000136233
TENM3
si:dkey-237h12.3
chr25_+_27923846 3.76 ENSDART00000047007
slc13a1
solute carrier family 13 member 1
chr22_+_15438513 3.59 ENSDART00000010846
gpc5b
glypican 5b
chr8_+_31777633 3.59 ENSDART00000142519
oxct1a
3-oxoacid CoA transferase 1a
chr3_-_21061931 3.49 ENSDART00000036741
fam57ba
family with sequence similarity 57, member Ba
chr4_+_8376362 3.43 ENSDART00000138653
ENSDART00000132647
erc1b
ELKS/RAB6-interacting/CAST family member 1b
chr22_-_237651 3.40 ENSDART00000075210
zgc:66156
zgc:66156
chr18_+_1615 3.40 ENSDART00000082450
homer2
homer scaffolding protein 2
chr18_+_3169579 3.39 ENSDART00000164724
ENSDART00000186340
ENSDART00000181247
ENSDART00000168056
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr13_-_41482064 3.34 ENSDART00000188322
ENSDART00000164732
pcdh15a
protocadherin-related 15a
chr8_+_28667236 3.31 ENSDART00000101159
slc13a3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr17_+_33296852 3.28 ENSDART00000154580
dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr17_-_3303805 3.25 ENSDART00000169136
CABZ01007222.1

chr18_+_3243292 3.22 ENSDART00000166580
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr1_+_23230459 3.14 ENSDART00000147857
si:dkey-92j12.5
si:dkey-92j12.5
chr14_+_14225048 3.12 ENSDART00000168749
nlgn3a
neuroligin 3a
chr13_+_2523032 3.10 ENSDART00000172261
lhb
luteinizing hormone, beta polypeptide
chr9_+_55075526 3.05 ENSDART00000139555
ENSDART00000133864
gpr143
G protein-coupled receptor 143
chr11_-_37411492 3.05 ENSDART00000166468
erc2
ELKS/RAB6-interacting/CAST family member 2
chr8_-_7386978 3.05 ENSDART00000058321
lhfpl4b
LHFPL tetraspan subfamily member 4b
chr3_+_14317802 3.01 ENSDART00000162023
plppr2a
phospholipid phosphatase related 2a
chr10_-_22918214 3.00 ENSDART00000163908
rnasekb
ribonuclease, RNase K b
chr14_+_52413846 2.96 ENSDART00000160952
noa1
nitric oxide associated 1
chr25_-_37435060 2.96 ENSDART00000102855
ENSDART00000148566
pdhx
pyruvate dehydrogenase complex, component X
chr2_+_3472832 2.95 ENSDART00000115278
cx47.1
connexin 47.1
chr13_+_30912385 2.89 ENSDART00000182642
drgx
dorsal root ganglia homeobox
chr6_+_10338554 2.89 ENSDART00000186936
cobll1a
cordon-bleu WH2 repeat protein-like 1a
chr15_+_47386939 2.86 ENSDART00000128224
FO904873.1

chr8_+_54055390 2.86 ENSDART00000102696
magi1a
membrane associated guanylate kinase, WW and PDZ domain containing 1a
chr14_-_36409960 2.85 ENSDART00000173140
asb5a
ankyrin repeat and SOCS box containing 5a
chr24_-_28711176 2.85 ENSDART00000105753
olfm3a
olfactomedin 3a
chr10_+_7182423 2.81 ENSDART00000186788
psd3l
pleckstrin and Sec7 domain containing 3, like
chr5_-_72178739 2.76 ENSDART00000050971
rab14l
RAB14, member RAS oncogene family, like
chr2_-_15041846 2.75 ENSDART00000139050
si:dkey-10f21.4
si:dkey-10f21.4
chr8_+_28667021 2.73 ENSDART00000184292
slc13a3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr15_+_45591669 2.73 ENSDART00000157459
atg16l1
ATG16 autophagy related 16-like 1 (S. cerevisiae)
chr18_-_46010 2.72 ENSDART00000052641
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr4_-_4535189 2.70 ENSDART00000057519
zgc:194209
zgc:194209
chr11_-_12512122 2.67 ENSDART00000145338
si:dkey-27d5.3
si:dkey-27d5.3
chr9_-_22158784 2.65 ENSDART00000167850
crygm2d14
crystallin, gamma M2d14
chr14_+_14224730 2.62 ENSDART00000180112
ENSDART00000184891
ENSDART00000174760
nlgn3a
neuroligin 3a
chr14_+_19258702 2.62 ENSDART00000187087
ENSDART00000005738
slitrk2
SLIT and NTRK-like family, member 2
chr12_-_4651988 2.60 ENSDART00000182836
si:ch211-255p10.4
si:ch211-255p10.4
chr22_+_15438872 2.58 ENSDART00000139800
gpc5b
glypican 5b
chr17_-_6382392 2.55 ENSDART00000188051
ENSDART00000192560
ENSDART00000137389
ENSDART00000115389
txlnbb
taxilin beta b
chr21_-_4793686 2.52 ENSDART00000158232
notch1a
notch 1a
chr7_-_24994722 2.46 ENSDART00000131671
rcor2
REST corepressor 2
chr17_-_20979077 2.46 ENSDART00000006676
phyhipla
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr1_-_625875 2.45 ENSDART00000167331
appa
amyloid beta (A4) precursor protein a
chr11_+_30057762 2.44 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr7_-_52842007 2.43 ENSDART00000182710
map1aa
microtubule-associated protein 1Aa
chr5_-_21044693 2.42 ENSDART00000140298
si:dkey-13n15.2
si:dkey-13n15.2
chr23_-_28294763 2.39 ENSDART00000139537
znf385a
zinc finger protein 385A
chr9_+_34380299 2.37 ENSDART00000131705
lamp1
lysosomal-associated membrane protein 1
chr7_+_36035432 2.37 ENSDART00000179004
irx3a
iroquois homeobox 3a
chr12_+_40905427 2.35 ENSDART00000170526
ENSDART00000185771
ENSDART00000193945
CDH18
cadherin 18
chr13_+_31172833 2.35 ENSDART00000176378
CR931802.3

chr17_-_52587598 2.34 ENSDART00000061497
si:ch211-173a9.6
si:ch211-173a9.6
chr13_+_30912938 2.26 ENSDART00000190003
drgx
dorsal root ganglia homeobox
chr21_+_29077509 2.26 ENSDART00000128561
ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr8_-_44015210 2.24 ENSDART00000186879
ENSDART00000188965
ENSDART00000001313
ENSDART00000188902
ENSDART00000185935
ENSDART00000147869
rimbp2
rimbp2
RIMS binding protein 2
RIMS binding protein 2
chr22_+_12366516 2.23 ENSDART00000157802
r3hdm1
R3H domain containing 1
chr6_-_44711942 2.21 ENSDART00000055035
cntn3b
contactin 3b
chr6_+_518979 2.20 ENSDART00000151012
CACNA1I (1 of many)
si:ch73-379f7.5
chr4_+_38344 2.15 ENSDART00000170197
ENSDART00000175348
phtf2
putative homeodomain transcription factor 2
chr15_-_16323750 2.13 ENSDART00000028500
nxn
nucleoredoxin
chr6_-_3978919 2.12 ENSDART00000167753
slc25a12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr13_-_8279533 2.12 ENSDART00000109666
si:ch211-250c4.5
si:ch211-250c4.5
chr2_+_28889936 2.08 ENSDART00000078232
cdh10a
cadherin 10, type 2a (T2-cadherin)
chr15_+_24691088 2.08 ENSDART00000110618
LRRC75A
si:dkey-151p21.7
chr21_-_40557281 2.07 ENSDART00000172327
taok1b
TAO kinase 1b
chr2_-_53896300 2.06 ENSDART00000161221
capsla
calcyphosine-like a
chr16_-_20492799 2.04 ENSDART00000014769
chn2
chimerin 2
chr6_+_42587637 2.01 ENSDART00000179964
camkva
CaM kinase-like vesicle-associated a
chr14_-_4043818 2.01 ENSDART00000179870
snx25
sorting nexin 25
chr1_+_40562540 2.00 ENSDART00000122059
scoca
short coiled-coil protein a
chr13_-_48756036 2.00 ENSDART00000035018
ENSDART00000132895
ntpcr
nucleoside-triphosphatase, cancer-related
chr16_+_31511739 1.99 ENSDART00000049420
ndrg1b
N-myc downstream regulated 1b
chr12_+_31735159 1.97 ENSDART00000185442
RNF157
si:dkey-49c17.3
chr24_+_12200260 1.95 ENSDART00000181391
CR855257.2

chr7_+_58843700 1.94 ENSDART00000159500
ENSDART00000158436
lypla1
lysophospholipase I
chr12_-_6551681 1.89 ENSDART00000145413
si:ch211-253p2.2
si:ch211-253p2.2
chr18_+_50278858 1.87 ENSDART00000014582
si:dkey-105e17.1
si:dkey-105e17.1
chr7_-_24994568 1.87 ENSDART00000002961
rcor2
REST corepressor 2
chr1_-_21529641 1.80 ENSDART00000135905
wdr19
WD repeat domain 19
chr22_-_20924564 1.78 ENSDART00000100642
ENSDART00000032770
ell
elongation factor RNA polymerase II
chr13_-_25632756 1.77 ENSDART00000077627
ENSDART00000139237
ret
ret proto-oncogene receptor tyrosine kinase
chr17_-_14836320 1.75 ENSDART00000157051
nid2a
nidogen 2a (osteonidogen)
chr4_+_5798223 1.73 ENSDART00000059440
si:ch73-352p4.8
si:ch73-352p4.8
chr20_+_1960092 1.70 ENSDART00000191892
CABZ01103860.1

chr20_+_26892761 1.68 ENSDART00000133293
ftr97
finTRIM family, member 97
chr20_+_11800063 1.67 ENSDART00000152230
si:ch211-155o21.4
si:ch211-155o21.4
chr10_+_8680730 1.65 ENSDART00000011987
isl1l
islet1, like
chr19_+_1999838 1.64 ENSDART00000166669
btd
biotinidase
chr1_-_1627487 1.63 ENSDART00000166094
clic6
chloride intracellular channel 6
chr23_+_16620801 1.61 ENSDART00000189859
ENSDART00000184578
snphb
syntaphilin b
chr22_+_2207502 1.61 ENSDART00000169162
si:dkeyp-79b7.12
si:dkeyp-79b7.12
chr24_+_42948 1.60 ENSDART00000122785
tmx3b
thioredoxin related transmembrane protein 3b
chr22_-_3449282 1.60 ENSDART00000136798
ptprsa
protein tyrosine phosphatase, receptor type, s, a
chr11_+_30058139 1.60 ENSDART00000112254
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr8_+_26874924 1.55 ENSDART00000141794
rimkla
ribosomal modification protein rimK-like family member A
chr15_+_1119114 1.55 ENSDART00000102224
p2ry12
purinergic receptor P2Y12
chr25_+_26923193 1.54 ENSDART00000187364
grm8b
glutamate receptor, metabotropic 8b
chr23_-_28692581 1.54 ENSDART00000078141
ribc1
RIB43A domain with coiled-coils 1
chr2_-_10632431 1.54 ENSDART00000122709
mtf2
metal response element binding transcription factor 2
chr2_+_25019387 1.54 ENSDART00000142601
stag1a
stromal antigen 1a
chr1_+_41690402 1.53 ENSDART00000177298
fbxo41
F-box protein 41
chr4_-_10958074 1.53 ENSDART00000150478
si:ch211-161n3.4
si:ch211-161n3.4
chr16_+_25296389 1.52 ENSDART00000114528
tbc1d31
TBC1 domain family, member 31
chr14_+_8328645 1.51 ENSDART00000127494
nrg2b
neuregulin 2b
chr12_+_47909026 1.49 ENSDART00000192472
tbata
thymus, brain and testes associated
chr15_-_25613114 1.49 ENSDART00000182431
ENSDART00000187405
taok1a
TAO kinase 1a
chr23_+_21414005 1.48 ENSDART00000144686
iffo2a
intermediate filament family orphan 2a
chr10_+_16092671 1.46 ENSDART00000182761
ENSDART00000154835
megf10
multiple EGF-like-domains 10
chr17_-_52941606 1.44 ENSDART00000155310
zgc:154061
zgc:154061
chr7_-_36358735 1.43 ENSDART00000188392
fto
fat mass and obesity associated
chr7_-_36358303 1.43 ENSDART00000130028
fto
fat mass and obesity associated
chr18_-_45736 1.40 ENSDART00000148373
ENSDART00000148950
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr8_-_50346246 1.39 ENSDART00000025008
stc1
stanniocalcin 1
chr13_-_133520 1.38 ENSDART00000180874
FO904997.1

chr7_-_59514547 1.37 ENSDART00000168457
slx1b
SLX1 homolog B, structure-specific endonuclease subunit
chr10_+_33990572 1.37 ENSDART00000138547
fryb
furry homolog b (Drosophila)
chr23_+_2361184 1.36 ENSDART00000184469
CABZ01048666.1

chr11_-_45141309 1.35 ENSDART00000181736
cant1b
calcium activated nucleotidase 1b
chr14_-_38843690 1.35 ENSDART00000183629
spdl1
spindle apparatus coiled-coil protein 1
chr5_-_68779747 1.35 ENSDART00000192636
ENSDART00000188039
mepce
methylphosphate capping enzyme
chr6_-_32726848 1.34 ENSDART00000155294
zc3h3
zinc finger CCCH-type containing 3
chr3_+_14339728 1.34 ENSDART00000184127
plppr2a
phospholipid phosphatase related 2a
chr21_-_13225402 1.33 ENSDART00000080347
wdr34
WD repeat domain 34
chr7_-_5396154 1.32 ENSDART00000172980
arhgef11
Rho guanine nucleotide exchange factor (GEF) 11
chr3_-_18575868 1.31 ENSDART00000122968
aqp8b
aquaporin 8b
chr21_-_22709251 1.29 ENSDART00000140032
si:dkeyp-69c1.9
si:dkeyp-69c1.9
chr8_+_7756893 1.29 ENSDART00000191894
fgd1
FYVE, RhoGEF and PH domain containing 1
chr15_+_34062460 1.28 ENSDART00000164654
si:dkey-30e9.6
si:dkey-30e9.6

Network of associatons between targets according to the STRING database.

First level regulatory network of si:dkey-149i17.7_zic1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 16.2 GO:0021557 oculomotor nerve development(GO:0021557)
3.1 12.5 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
1.6 6.4 GO:0006740 NADPH regeneration(GO:0006740)
1.4 15.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
1.4 4.1 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
1.1 6.6 GO:0003232 bulbus arteriosus development(GO:0003232)
1.0 5.0 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
1.0 2.9 GO:0042245 RNA repair(GO:0042245)
0.9 9.7 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.8 2.5 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.7 3.6 GO:0046952 ketone body catabolic process(GO:0046952)
0.7 2.8 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.6 7.0 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.6 6.0 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.6 13.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.5 2.7 GO:0039689 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.5 5.7 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.5 7.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.4 1.3 GO:1900182 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.4 3.1 GO:0030728 ovulation(GO:0030728)
0.4 3.1 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.4 4.3 GO:0034381 plasma lipoprotein particle clearance(GO:0034381)
0.4 3.4 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.4 1.6 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.4 1.2 GO:0003403 optic vesicle formation(GO:0003403)
0.4 1.5 GO:0001774 microglial cell activation(GO:0001774)
0.4 1.8 GO:1901166 branchiomeric skeletal muscle development(GO:0014707) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.3 5.1 GO:0035493 SNARE complex assembly(GO:0035493)
0.3 9.4 GO:0099645 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.3 1.6 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.3 9.3 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.3 0.9 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.3 1.8 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.3 5.5 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.3 2.0 GO:0061635 regulation of protein complex stability(GO:0061635)
0.3 2.0 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.3 4.1 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.2 0.7 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.2 8.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.2 5.0 GO:0006491 N-glycan processing(GO:0006491)
0.2 0.7 GO:1901006 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.2 2.1 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.2 3.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.2 2.3 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.2 1.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.2 1.0 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.2 1.2 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 1.8 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.2 1.1 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.2 2.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.9 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 5.8 GO:0072114 pronephros morphogenesis(GO:0072114)
0.1 0.7 GO:0007624 ultradian rhythm(GO:0007624)
0.1 3.8 GO:0008272 sulfate transport(GO:0008272)
0.1 11.4 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 1.2 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.1 0.4 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 1.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 0.6 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 10.3 GO:0006612 protein targeting to membrane(GO:0006612)
0.1 0.4 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.1 1.6 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.1 2.1 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.1 0.4 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.1 6.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.9 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.4 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.3 GO:0015695 organic cation transport(GO:0015695)
0.1 2.0 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 1.0 GO:0038203 TORC2 signaling(GO:0038203)
0.1 2.4 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 4.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 4.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 5.5 GO:0051781 positive regulation of cell division(GO:0051781)
0.1 0.7 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.2 GO:0048327 axial mesoderm formation(GO:0048320) axial mesodermal cell differentiation(GO:0048321) axial mesodermal cell fate commitment(GO:0048322) axial mesodermal cell fate specification(GO:0048327) Spemann organizer formation at the embryonic shield(GO:0060063)
0.1 1.1 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 3.8 GO:0016575 histone deacetylation(GO:0016575)
0.1 1.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 2.8 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 6.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 3.1 GO:0006414 translational elongation(GO:0006414)
0.1 6.6 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.7 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 2.1 GO:0034332 adherens junction organization(GO:0034332)
0.0 1.3 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 3.0 GO:0007605 sensory perception of sound(GO:0007605)
0.0 1.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 1.7 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.4 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.1 GO:0006844 acyl carnitine transport(GO:0006844)
0.0 1.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.2 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 4.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 3.6 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 1.5 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.6 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 1.5 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.4 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.7 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 3.2 GO:0007283 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 2.7 GO:0006821 chloride transport(GO:0006821)
0.0 0.3 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 2.4 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.0 0.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 2.6 GO:0021782 glial cell development(GO:0021782)
0.0 1.4 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.1 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 1.1 GO:0006096 glycolytic process(GO:0006096)
0.0 0.7 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.5 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 1.5 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.4 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 1.4 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.8 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 1.5 GO:0030239 myofibril assembly(GO:0030239)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 10.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
1.1 5.6 GO:0097224 sperm connecting piece(GO:0097224)
0.5 5.5 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.5 12.5 GO:0043195 terminal bouton(GO:0043195)
0.4 3.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.3 6.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.3 3.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 5.0 GO:0030315 T-tubule(GO:0030315)
0.3 8.0 GO:0035371 microtubule plus-end(GO:0035371)
0.3 6.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 3.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 1.4 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.2 1.8 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 6.5 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.2 4.3 GO:0032420 stereocilium(GO:0032420)
0.2 0.5 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.2 9.4 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 1.6 GO:0044295 axonal growth cone(GO:0044295)
0.1 2.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 2.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 4.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 4.3 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 1.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.4 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 2.7 GO:0000421 autophagosome membrane(GO:0000421)
0.1 2.8 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.5 GO:0008278 cohesin complex(GO:0008278)
0.1 5.1 GO:0031201 SNARE complex(GO:0031201)
0.1 0.9 GO:0071564 npBAF complex(GO:0071564)
0.1 1.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.7 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 2.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 2.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0032421 stereocilium bundle(GO:0032421)
0.0 1.8 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 11.0 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.6 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.4 GO:0030427 site of polarized growth(GO:0030427)
0.0 2.4 GO:0043025 neuronal cell body(GO:0043025)
0.0 16.8 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 8.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 6.2 GO:0043005 neuron projection(GO:0043005)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.9 GO:0016607 nuclear speck(GO:0016607)
0.0 1.5 GO:0005882 intermediate filament(GO:0005882)
0.0 8.8 GO:0045202 synapse(GO:0045202)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 15.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
1.6 6.4 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
1.5 6.0 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
1.1 4.3 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
1.0 3.1 GO:0072545 tyrosine binding(GO:0072545)
0.9 9.7 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.7 3.6 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.7 2.9 GO:1990931 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.7 7.1 GO:0016805 dipeptidase activity(GO:0016805)
0.7 6.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.6 5.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.5 7.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.5 2.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.5 1.5 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.4 11.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.4 3.0 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.4 6.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.3 2.1 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.3 1.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.3 5.5 GO:0001671 ATPase activator activity(GO:0001671)
0.3 2.7 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.2 1.6 GO:0016972 thiol oxidase activity(GO:0016972)
0.2 8.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.4 GO:0043515 kinetochore binding(GO:0043515)
0.2 1.5 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.2 0.6 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 1.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 2.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 4.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 3.8 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.2 6.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 8.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 7.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 4.1 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 6.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.3 GO:0015250 water channel activity(GO:0015250)
0.1 2.9 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.7 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 6.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.1 GO:0015157 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 5.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.4 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 0.4 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.9 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 10.8 GO:0051082 unfolded protein binding(GO:0051082)
0.1 1.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.5 GO:0005112 Notch binding(GO:0005112)
0.1 0.4 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 1.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 4.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.9 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 5.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 1.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.7 GO:0045503 dynein light chain binding(GO:0045503)
0.0 1.3 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.0 4.0 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 4.7 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 2.5 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 1.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.0 GO:0030145 manganese ion binding(GO:0030145)
0.0 27.8 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.7 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 3.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.6 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 3.2 GO:0005179 hormone activity(GO:0005179)
0.0 1.6 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 1.3 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 7.0 GO:0003924 GTPase activity(GO:0003924)
0.0 0.7 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.2 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.6 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.3 5.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 1.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 4.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 8.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 7.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.6 9.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.6 8.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.5 4.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.4 3.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 4.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 5.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 3.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 6.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 2.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.9 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 1.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.7 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 6.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.8 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 4.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 4.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 2.7 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 1.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)