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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for snai2

Z-value: 0.67

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Transcription factors associated with snai2

Gene Symbol Gene ID Gene Info
snai2
ENSDARG00000040046 snail family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
snai2dr11_v1_chr24_+_35387517_35387517-0.205.1e-02Click!

Activity profile of snai2 motif

Sorted Z-values of snai2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_106689 10.84 ENSDART00000185007
apoa1b
apolipoprotein A-Ib
chr20_+_10538025 8.74 ENSDART00000129762
serpina1l
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like
chr15_+_20239141 6.91 ENSDART00000101152
ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr22_+_661711 6.58 ENSDART00000113795
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr22_+_661505 6.20 ENSDART00000149460
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr21_-_30658509 5.98 ENSDART00000139764
si:dkey-22f5.9
si:dkey-22f5.9
chr25_-_17395315 5.45 ENSDART00000064596
cyp2x8
cytochrome P450, family 2, subfamily X, polypeptide 8
chr19_-_48312109 5.42 ENSDART00000161103
si:ch73-359m17.9
si:ch73-359m17.9
chr7_-_53117131 5.11 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cdh1
cadherin 1, type 1, E-cadherin (epithelial)
chr2_-_32643738 4.64 ENSDART00000112452
si:dkeyp-73d8.9
si:dkeyp-73d8.9
chr3_-_15080226 4.63 ENSDART00000109818
ENSDART00000139835
nme4
NME/NM23 nucleoside diphosphate kinase 4
chr7_-_26306546 4.63 ENSDART00000140817
zgc:77439
zgc:77439
chr11_+_329687 4.62 ENSDART00000172882
cyp27b1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr23_-_12735434 4.44 ENSDART00000139166
si:dkey-96f10.1
si:dkey-96f10.1
chr7_+_52122224 4.41 ENSDART00000174268
cyp2x12
cytochrome P450, family 2, subfamily X, polypeptide 12
chr2_+_4208323 4.00 ENSDART00000167906
gata6
GATA binding protein 6
chr20_-_33556983 3.99 ENSDART00000168798
rock2bl
rho-associated, coiled-coil containing protein kinase 2b, like
chr14_+_15155684 3.94 ENSDART00000167966
zgc:158852
zgc:158852
chr1_+_56180416 3.74 ENSDART00000089358
crb3b
crumbs homolog 3b
chr20_-_43743700 3.54 ENSDART00000100620
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr15_+_46606090 3.52 ENSDART00000020921
CABZ01044048.1

chr19_+_791538 3.34 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr12_-_4243268 3.28 ENSDART00000131275
zgc:92313
zgc:92313
chr17_-_49412313 3.21 ENSDART00000152100
mthfd1b
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr18_+_45666489 3.20 ENSDART00000180147
ENSDART00000151351
prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr14_-_14659023 3.15 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
nsdhl
NAD(P) dependent steroid dehydrogenase-like
chr7_+_14005111 3.05 ENSDART00000187365
furina
furin (paired basic amino acid cleaving enzyme) a
chr20_-_3238110 3.05 ENSDART00000008077
spint1b
serine peptidase inhibitor, Kunitz type 1 b
chr3_+_1179601 2.91 ENSDART00000173378
triobpb
TRIO and F-actin binding protein b
chr13_+_37022601 2.89 ENSDART00000131800
ENSDART00000041300
esr2b
estrogen receptor 2b
chr21_+_45839917 2.86 ENSDART00000189305
faxdc2
fatty acid hydroxylase domain containing 2
chr4_-_9891874 2.86 ENSDART00000067193
adm2a
adrenomedullin 2a
chr16_+_23961276 2.85 ENSDART00000192754
apoeb
apolipoprotein Eb
chr5_-_6561376 2.83 ENSDART00000099570
tnks1bp1
tankyrase 1 binding protein 1
chr18_+_21061216 2.76 ENSDART00000141739
fam169b
family with sequence similarity 169, member B
chr10_+_19596214 2.74 ENSDART00000183110
CABZ01059626.1

chr6_-_37749711 2.67 ENSDART00000078324
nipa1
non imprinted in Prader-Willi/Angelman syndrome 1
chr3_-_32965848 2.66 ENSDART00000050930
casp6
caspase 6, apoptosis-related cysteine peptidase
chr20_-_23426339 2.62 ENSDART00000004625
zar1
zygote arrest 1
chr1_+_12135129 2.57 ENSDART00000126020
spink4
serine peptidase inhibitor, Kazal type 4
chr2_+_20539402 2.54 ENSDART00000129585
si:ch73-14h1.2
si:ch73-14h1.2
chr21_-_43666420 2.54 ENSDART00000139008
ENSDART00000183996
ENSDART00000183395
si:dkey-229d11.3
si:dkey-229d11.5
si:dkey-229d11.3
si:dkey-229d11.5
chr23_-_44574059 2.50 ENSDART00000123007
si:ch73-160p18.3
si:ch73-160p18.3
chr14_+_34514336 2.48 ENSDART00000024440
foxi3b
forkhead box I3b
chr11_+_43431289 2.38 ENSDART00000192526
slc29a1b
solute carrier family 29 (equilibrative nucleoside transporter), member 1b
chr20_-_33583779 2.35 ENSDART00000097823
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr16_-_17713859 2.30 ENSDART00000149275
zgc:174935
zgc:174935
chr8_-_38022298 2.30 ENSDART00000067809
rab11fip1a
RAB11 family interacting protein 1 (class I) a
chr6_+_7466223 2.28 ENSDART00000148908
erbb3a
erb-b2 receptor tyrosine kinase 3a
chr11_-_25853212 2.18 ENSDART00000145655
tmem51b
transmembrane protein 51b
chr6_-_43449013 2.14 ENSDART00000122423
eevs
2-epi-5-epi-valiolone synthase
chr2_+_111919 2.11 ENSDART00000149391
fggy
FGGY carbohydrate kinase domain containing
chr4_-_77557279 2.08 ENSDART00000180113
AL935186.10

chr14_+_48862987 2.05 ENSDART00000167810
zgc:154054
zgc:154054
chr7_+_30178453 2.05 ENSDART00000174420
si:ch211-107o10.3
si:ch211-107o10.3
chr17_+_3124129 2.00 ENSDART00000155323
zgc:136872
zgc:136872
chr17_-_24575893 1.92 ENSDART00000141914
aftphb
aftiphilin b
chr12_+_48784731 1.90 ENSDART00000158348
zmiz1b
zinc finger, MIZ-type containing 1b
chr20_-_23439011 1.89 ENSDART00000022887
slc10a4
solute carrier family 10, member 4
chr1_-_59313465 1.89 ENSDART00000158067
ENSDART00000159419
txndc11
thioredoxin domain containing 11
chr19_-_18313303 1.87 ENSDART00000164644
ENSDART00000167480
ENSDART00000163104
si:dkey-208k4.2
si:dkey-208k4.2
chr7_-_51773166 1.83 ENSDART00000054591
bmp15
bone morphogenetic protein 15
chr17_+_51906053 1.82 ENSDART00000159072
ENSDART00000056869
flvcr2a
feline leukemia virus subgroup C cellular receptor family, member 2a
chr10_+_9550419 1.80 ENSDART00000064977
si:ch211-243g18.2
si:ch211-243g18.2
chr17_-_25331439 1.76 ENSDART00000155422
ENSDART00000082324
zpcx
zona pellucida protein C
chr3_+_18097700 1.71 ENSDART00000021634
wfikkn2a
info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a
chr3_-_55511569 1.71 ENSDART00000108995
tex2
testis expressed 2
chr22_+_7480465 1.70 ENSDART00000034545
CELA1 (1 of many)
zgc:92745
chr17_+_3128273 1.70 ENSDART00000122453
zgc:136872
zgc:136872
chr3_+_48561112 1.67 ENSDART00000159682
slc16a5b
solute carrier family 16 (monocarboxylate transporter), member 5b
chr8_-_4892913 1.64 ENSDART00000126808
igsf9b
immunoglobulin superfamily, member 9b
chr4_-_68563862 1.63 ENSDART00000182970
BX548011.2

chr7_+_67468999 1.61 ENSDART00000176368
rpl13
ribosomal protein L13
chr5_-_57204352 1.57 ENSDART00000171252
ENSDART00000180727
man2a1
mannosidase, alpha, class 2A, member 1
chr12_-_990149 1.56 ENSDART00000054367
kdelr2b
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr14_-_26482096 1.55 ENSDART00000187280
smad5
SMAD family member 5
chr8_+_15254564 1.53 ENSDART00000024433
slc5a9
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr17_-_39886628 1.52 ENSDART00000002217
zmp:0000000545
zmp:0000000545
chr12_-_7710563 1.52 ENSDART00000187382
CABZ01050062.1

chr3_+_43086548 1.50 ENSDART00000163579
si:dkey-43p13.5
si:dkey-43p13.5
chr2_-_58075414 1.48 ENSDART00000161920
nectin4
nectin cell adhesion molecule 4
chr18_-_38271298 1.48 ENSDART00000143016
caprin1b
cell cycle associated protein 1b
chr25_-_16600811 1.43 ENSDART00000011397
cpa2
carboxypeptidase A2 (pancreatic)
chr14_+_26546175 1.42 ENSDART00000105932
si:dkeyp-110e4.11
si:dkeyp-110e4.11
chr15_-_36365840 1.42 ENSDART00000192926
si:dkey-23k10.3
si:dkey-23k10.3
chr9_-_33329700 1.38 ENSDART00000147265
ENSDART00000140039
rpl8
ribosomal protein L8
chr23_+_26026383 1.35 ENSDART00000141553
pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr5_+_6670945 1.33 ENSDART00000185686
pxna
paxillin a
chr14_+_3495542 1.32 ENSDART00000168934
gstp2
glutathione S-transferase pi 2
chr15_-_19128705 1.32 ENSDART00000152428
arhgap32a
Rho GTPase activating protein 32a
chr21_+_39197628 1.30 ENSDART00000113607
cpdb
carboxypeptidase D, b
chr18_-_7539166 1.30 ENSDART00000133541
si:dkey-30c15.2
si:dkey-30c15.2
chr4_+_77993977 1.29 ENSDART00000174118
terfa
telomeric repeat binding factor a
chr21_+_30351256 1.29 ENSDART00000078341
foxi3a
forkhead box I3a
chr21_+_39197418 1.27 ENSDART00000076000
cpdb
carboxypeptidase D, b
chr15_-_47929455 1.27 ENSDART00000064462
psma6l
proteasome subunit alpha 6, like
chr23_-_44677315 1.27 ENSDART00000143054
kif1c
kinesin family member 1C
chr22_-_22231720 1.26 ENSDART00000160165
ap3d1
adaptor-related protein complex 3, delta 1 subunit
chr20_+_30797329 1.25 ENSDART00000145066
nhsl1b
NHS-like 1b
chr16_+_41060161 1.25 ENSDART00000141130
scap
SREBF chaperone
chr11_-_45429199 1.25 ENSDART00000173111
rfc4
replication factor C (activator 1) 4
chr1_-_59139599 1.24 ENSDART00000152233
si:ch1073-110a20.3
si:ch1073-110a20.3
chr17_-_2596125 1.23 ENSDART00000175740
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr16_+_26547152 1.21 ENSDART00000141393
ptpn3
protein tyrosine phosphatase, non-receptor type 3
chr15_-_43164591 1.20 ENSDART00000171305
ap1s3a
adaptor-related protein complex 1, sigma 3 subunit, a
chr3_+_49576662 1.18 ENSDART00000162275
CR394535.1

chr22_-_15578402 1.18 ENSDART00000062986
hsh2d
hematopoietic SH2 domain containing
chr25_-_12730260 1.16 ENSDART00000171834
klhdc4
kelch domain containing 4
chr2_-_722156 1.15 ENSDART00000045770
ENSDART00000169498
foxq1a
forkhead box Q1a
chr18_-_37241080 1.14 ENSDART00000126421
ENSDART00000078064
six9
SIX homeobox 9
chr8_-_21184759 1.13 ENSDART00000139257
gls2a
glutaminase 2a (liver, mitochondrial)
chr3_+_49521106 1.12 ENSDART00000162799
crb3a
crumbs homolog 3a
chr6_+_7555614 1.11 ENSDART00000187590
myh10
myosin, heavy chain 10, non-muscle
chr23_+_2728095 1.11 ENSDART00000066086
zgc:114123
zgc:114123
chr19_-_35439237 1.08 ENSDART00000145883
anln
anillin, actin binding protein
chr17_-_25330775 1.07 ENSDART00000154048
zpcx
zona pellucida protein C
chr3_+_32553714 1.06 ENSDART00000165638
pax10
paired box 10
chr3_-_37758487 1.06 ENSDART00000150938
si:dkey-260c8.6
si:dkey-260c8.6
chr16_+_27444098 1.04 ENSDART00000157690
invs
inversin
chr13_+_2894536 1.02 ENSDART00000183678
CABZ01087629.1

chr10_-_3416258 1.01 ENSDART00000005168
ddx55
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr21_-_20725853 1.00 ENSDART00000114502
si:ch211-22d5.2
si:ch211-22d5.2
chr19_+_4061699 0.99 ENSDART00000158309
ENSDART00000166512
btr25
btr26
bloodthirsty-related gene family, member 25
bloodthirsty-related gene family, member 26
chr25_+_5249513 0.99 ENSDART00000126814
CABZ01039863.1

chr23_+_17387325 0.97 ENSDART00000083947
ptk6b
PTK6 protein tyrosine kinase 6b
chr1_-_24349759 0.97 ENSDART00000142740
ENSDART00000177989
lrba
LPS-responsive vesicle trafficking, beach and anchor containing
chr10_+_4924388 0.96 ENSDART00000108595
slc46a2
solute carrier family 46 member 2
chr8_-_4100365 0.96 ENSDART00000142846
cux2b
cut-like homeobox 2b
chr2_-_17694504 0.93 ENSDART00000133709
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr25_-_22889519 0.92 ENSDART00000128250
mob2a
MOB kinase activator 2a
chr7_-_26571994 0.91 ENSDART00000128801
si:dkey-62k3.6
si:dkey-62k3.6
chr5_+_50913357 0.89 ENSDART00000092938
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr24_-_5911973 0.89 ENSDART00000077933
ENSDART00000077922
pimr64
Pim proto-oncogene, serine/threonine kinase, related 64
chr5_-_68244564 0.89 ENSDART00000169350
CABZ01083944.1

chr14_-_28052474 0.89 ENSDART00000172948
ENSDART00000135337
TSC22D3 (1 of many)
zgc:64189
si:ch211-220e11.3
zgc:64189
chr19_+_31904836 0.88 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tpd52
tumor protein D52
chr22_-_38274188 0.87 ENSDART00000139420
ENSDART00000015117
elavl2
ELAV like neuron-specific RNA binding protein 2
chr3_-_41292569 0.87 ENSDART00000111856
sdk1a
sidekick cell adhesion molecule 1a
chr24_-_31904924 0.86 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
si:ch73-78o10.1
chr8_+_25302172 0.85 ENSDART00000046182
ENSDART00000145316
gstm.3
glutathione S-transferase mu tandem duplicate 3
chr19_+_4068134 0.85 ENSDART00000158285
btr26
bloodthirsty-related gene family, member 26
chr18_-_7810214 0.84 ENSDART00000139505
ENSDART00000139188
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr16_+_40301056 0.83 ENSDART00000058578
rspo3
R-spondin 3
chr21_-_217589 0.81 ENSDART00000185017
CZQB01146713.1

chr23_-_45501177 0.81 ENSDART00000150103
col24a1
collagen type XXIV alpha 1
chr6_+_56141852 0.78 ENSDART00000149665
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr22_-_209741 0.77 ENSDART00000171954
ora1
olfactory receptor class A related 1
chr7_+_36484598 0.76 ENSDART00000173595
chd9
chromodomain helicase DNA binding protein 9
chr8_-_29658171 0.76 ENSDART00000147755
mpeg1.3
macrophage expressed 1, tandem duplicate 3
chr2_-_57469115 0.75 ENSDART00000192201
pias4b
protein inhibitor of activated STAT, 4b
chr23_-_1144425 0.75 ENSDART00000098271
psmb11b
proteasome subunit beta11b
chr5_+_18014931 0.75 ENSDART00000142562
ascc2
activating signal cointegrator 1 complex subunit 2
chr5_-_32505109 0.74 ENSDART00000188219
ntmt1
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr6_-_55399214 0.74 ENSDART00000168367
ctsa
cathepsin A
chr17_+_26352372 0.74 ENSDART00000155177
grid1a
glutamate receptor, ionotropic, delta 1a
chr5_-_54712159 0.74 ENSDART00000149207
ccnb1
cyclin B1
chr16_+_50953842 0.73 ENSDART00000174709
si:dkeyp-97a10.1
si:dkeyp-97a10.1
chr10_+_37173029 0.73 ENSDART00000136510
ksr1a
kinase suppressor of ras 1a
chr17_+_1360192 0.73 ENSDART00000184561
siva1
SIVA1, apoptosis-inducing factor
chr23_+_27779452 0.72 ENSDART00000134785
kmt2d
lysine (K)-specific methyltransferase 2D
chr16_+_2565433 0.72 ENSDART00000188014
ENSDART00000171378
preb
prolactin regulatory element binding
chr5_+_42259002 0.72 ENSDART00000083778
eral1
Era-like 12S mitochondrial rRNA chaperone 1
chr16_-_2650341 0.71 ENSDART00000128169
ENSDART00000155432
ENSDART00000103722
lyplal1
lysophospholipase-like 1
chr8_-_11170114 0.71 ENSDART00000133532
si:ch211-204d2.4
si:ch211-204d2.4
chr12_-_2869565 0.71 ENSDART00000152772
zdhhc16b
zinc finger, DHHC-type containing 16b
chr13_-_51903150 0.71 ENSDART00000090644
mrpl2
mitochondrial ribosomal protein L2
chr10_-_44467384 0.70 ENSDART00000186382
CABZ01072089.1

chr7_-_45990681 0.70 ENSDART00000165441
si:ch211-260e23.7
si:ch211-260e23.7
chr14_-_38865800 0.69 ENSDART00000173047
gsr
glutathione reductase
chr18_+_5308392 0.68 ENSDART00000179072
DUT
deoxyuridine triphosphatase
chr6_+_13506841 0.66 ENSDART00000032331
gmppab
GDP-mannose pyrophosphorylase Ab
chr2_-_17235891 0.66 ENSDART00000144251
artnb
artemin b
chr4_-_20483954 0.66 ENSDART00000187240
napepld
N-acyl phosphatidylethanolamine phospholipase D
chr19_+_4800549 0.65 ENSDART00000056235
st3gal1l
ST3 beta-galactoside alpha-2,3-sialyltransferase 1, like
chr20_-_52902693 0.65 ENSDART00000166115
ENSDART00000161050
ctsbb
cathepsin Bb
chr20_-_41992878 0.65 ENSDART00000100967
si:dkeyp-114g9.1
si:dkeyp-114g9.1
chr7_+_20917966 0.64 ENSDART00000129161
wrap53
WD repeat containing, antisense to TP53
chr1_+_58290933 0.63 ENSDART00000140536
si:dkey-222h21.6
si:dkey-222h21.6
chr1_-_43892349 0.63 ENSDART00000148416
tacr3a
tachykinin receptor 3a
chr1_+_40308077 0.61 ENSDART00000138992
vwa10.2
von Willebrand factor A domain containing 10, tandem duplicate 2
chr10_+_1052591 0.61 ENSDART00000123405
unc5c
unc-5 netrin receptor C
chr15_-_434503 0.61 ENSDART00000122286
CABZ01056629.1

chr16_-_31791165 0.60 ENSDART00000148389
chd4b
chromodomain helicase DNA binding protein 4b
chr7_+_38090515 0.59 ENSDART00000131387
cebpg
CCAAT/enhancer binding protein (C/EBP), gamma
chr12_-_48312647 0.59 ENSDART00000114415
ascc1
activating signal cointegrator 1 complex subunit 1
chr23_+_27778670 0.59 ENSDART00000053863
kmt2d
lysine (K)-specific methyltransferase 2D
chr25_-_169291 0.58 ENSDART00000128344
lipcb
lipase, hepatic b
chr1_+_41609676 0.58 ENSDART00000183675
mogs
mannosyl-oligosaccharide glucosidase
chr17_-_52595932 0.58 ENSDART00000127225
si:ch211-173a9.7
si:ch211-173a9.7
chr4_-_60312069 0.58 ENSDART00000167207
si:dkey-248e17.4
si:dkey-248e17.4
chr20_-_25533739 0.58 ENSDART00000063064
cyp2ad6
cytochrome P450, family 2, subfamily AD, polypeptide 6
chr12_-_30359031 0.57 ENSDART00000192628
tdrd1
tudor domain containing 1
chr22_+_9091913 0.57 ENSDART00000186598
BX248395.1

chr6_+_22326624 0.56 ENSDART00000020333
rae1
ribonucleic acid export 1
chr7_+_24528430 0.56 ENSDART00000133022
si:dkeyp-75h12.2
si:dkeyp-75h12.2
chr16_-_33001153 0.55 ENSDART00000147941
me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr11_-_4596431 0.55 ENSDART00000181615
FHIT
si:ch211-63i20.3
chr2_+_43851983 0.55 ENSDART00000126413
nlrb5
NOD-like receptor family B, member 5
chr23_+_25201077 0.54 ENSDART00000136675
si:dkey-151g10.3
si:dkey-151g10.3
chr5_-_33959868 0.54 ENSDART00000143652
zgc:63972
zgc:63972

Network of associatons between targets according to the STRING database.

First level regulatory network of snai2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 10.8 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.9 2.8 GO:0034380 high-density lipoprotein particle assembly(GO:0034380) chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.9 3.8 GO:0009957 epidermal cell fate specification(GO:0009957)
0.9 5.1 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.8 4.0 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.5 1.8 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.5 1.8 GO:0097037 heme export(GO:0097037)
0.4 2.4 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.4 2.9 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.4 5.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.4 2.9 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.3 1.3 GO:0032208 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.3 4.6 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.3 1.1 GO:0008356 asymmetric cell division(GO:0008356)
0.3 1.6 GO:0006013 mannose metabolic process(GO:0006013)
0.3 1.0 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.3 4.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.3 4.3 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 0.7 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.2 1.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 3.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.2 3.0 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.2 10.4 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.2 0.8 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.2 1.1 GO:0070650 actin filament bundle distribution(GO:0070650)
0.2 0.7 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.2 0.7 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.2 1.3 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.2 2.7 GO:0015693 magnesium ion transport(GO:0015693)
0.2 0.5 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.2 0.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.4 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 1.3 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.1 1.1 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 1.1 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 1.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.8 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 0.7 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.7 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 1.5 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.1 0.6 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.1 1.9 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.4 GO:1902746 negative regulation of epithelial cell differentiation(GO:0030857) regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.8 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 1.1 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 13.0 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 2.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 1.2 GO:0007608 sensory perception of smell(GO:0007608)
0.1 1.4 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.9 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 5.8 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.1 2.9 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 0.6 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.1 0.4 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.1 0.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 3.1 GO:0001878 response to yeast(GO:0001878)
0.1 0.6 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.1 1.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 1.1 GO:0061055 myotome development(GO:0061055)
0.1 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.5 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.5 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.5 GO:0048478 replication fork protection(GO:0048478)
0.1 0.4 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 0.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 2.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.2 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.3 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.3 GO:0007340 acrosome reaction(GO:0007340)
0.1 1.3 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.6 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.5 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 0.2 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 0.6 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.4 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 1.1 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 0.2 GO:0035046 pronuclear migration(GO:0035046)
0.1 12.6 GO:0006954 inflammatory response(GO:0006954)
0.0 7.4 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.5 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.5 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0042420 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.0 0.9 GO:0030183 B cell differentiation(GO:0030183)
0.0 4.0 GO:0017148 negative regulation of translation(GO:0017148)
0.0 5.2 GO:0045055 regulated exocytosis(GO:0045055)
0.0 0.6 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.5 GO:1902307 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 1.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.3 GO:0043217 myelin maintenance(GO:0043217)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.4 GO:0001556 oocyte maturation(GO:0001556)
0.0 4.7 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 2.6 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.9 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.9 GO:0003341 cilium movement(GO:0003341)
0.0 0.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.3 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.7 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.5 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 1.0 GO:0048484 enteric nervous system development(GO:0048484)
0.0 2.3 GO:0008544 epidermis development(GO:0008544)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.1 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.9 GO:0010842 retina layer formation(GO:0010842)
0.0 1.9 GO:0016485 protein processing(GO:0016485)
0.0 0.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.5 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0050821 protein stabilization(GO:0050821)
0.0 0.5 GO:0032924 activin receptor signaling pathway(GO:0032924)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.8 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
1.0 14.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 1.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.3 5.1 GO:0030057 desmosome(GO:0030057)
0.3 0.8 GO:0005592 collagen type XI trimer(GO:0005592)
0.2 0.7 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 3.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 1.3 GO:0001650 fibrillar center(GO:0001650)
0.2 1.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 1.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.1 GO:0071546 pi-body(GO:0071546)
0.1 0.5 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 2.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.6 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 0.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 1.3 GO:0070187 telosome(GO:0070187)
0.1 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.4 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.8 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 1.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.5 GO:0032797 SMN complex(GO:0032797)
0.1 0.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.0 GO:0005839 proteasome core complex(GO:0005839)
0.1 1.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 3.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 3.0 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 2.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0048179 activin receptor complex(GO:0048179)
0.0 1.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 1.2 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.5 GO:0043596 nuclear replication fork(GO:0043596)
0.0 17.0 GO:0005615 extracellular space(GO:0005615)
0.0 1.3 GO:0005925 focal adhesion(GO:0005925)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 10.8 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.9 2.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.5 1.6 GO:0046923 ER retention sequence binding(GO:0046923)
0.5 4.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.5 3.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.5 2.3 GO:0038131 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.4 5.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.4 2.9 GO:1903924 estradiol binding(GO:1903924)
0.4 2.9 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.4 5.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 4.1 GO:0035804 structural constituent of egg coat(GO:0035804)
0.3 3.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.3 1.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 2.3 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.3 1.8 GO:0070698 type I activin receptor binding(GO:0070698)
0.3 0.8 GO:0072545 tyrosine binding(GO:0072545)
0.3 1.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.2 0.7 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.2 2.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2 1.8 GO:0015232 heme transporter activity(GO:0015232)
0.2 0.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 22.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 0.7 GO:0004475 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.2 1.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.2 10.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.2 4.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 4.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.6 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.7 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.1 1.1 GO:0034584 piRNA binding(GO:0034584)
0.1 2.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.1 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 3.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 4.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.5 GO:0031769 glucagon receptor binding(GO:0031769)
0.1 1.6 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 0.6 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 1.5 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.4 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.4 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 2.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.6 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.5 GO:0005355 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.0 0.4 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.5 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 2.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 1.4 GO:0019843 rRNA binding(GO:0019843)
0.0 0.9 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.6 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.4 GO:0005504 fatty acid binding(GO:0005504)
0.0 2.1 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 1.7 GO:0003823 antigen binding(GO:0003823)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 5.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.4 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 1.3 GO:0032934 sterol binding(GO:0032934)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.8 GO:0030276 clathrin binding(GO:0030276)
0.0 0.0 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 1.0 GO:0003678 DNA helicase activity(GO:0003678)
0.0 2.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 1.0 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.3 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 1.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.5 PID ALK2 PATHWAY ALK2 signaling events
0.1 3.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.7 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.7 PID ATR PATHWAY ATR signaling pathway
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 PID FOXO PATHWAY FoxO family signaling
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3 2.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 5.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 4.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 2.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 3.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 0.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.8 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 1.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 4.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.6 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 3.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation