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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for sox11a+sox11b

Z-value: 0.74

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Transcription factors associated with sox11a+sox11b

Gene Symbol Gene ID Gene Info
sox11a
ENSDARG00000077811 SRY-box transcription factor 11a
sox11b
ENSDARG00000095743 SRY-box transcription factor 11b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox11adr11_v1_chr17_-_35881841_358818410.526.9e-08Click!
sox11bdr11_v1_chr20_-_30035326_300353260.348.5e-04Click!

Activity profile of sox11a+sox11b motif

Sorted Z-values of sox11a+sox11b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_30282141 7.95 ENSDART00000122756
si:dkey-163f14.6
si:dkey-163f14.6
chr21_-_41305748 7.27 ENSDART00000170457
nsg2
neuronal vesicle trafficking associated 2
chr8_+_24861264 6.90 ENSDART00000099607
slc6a17
solute carrier family 6 (neutral amino acid transporter), member 17
chr2_-_32643738 6.13 ENSDART00000112452
si:dkeyp-73d8.9
si:dkeyp-73d8.9
chr17_-_48915427 5.62 ENSDART00000054781
lgals8b
galectin 8b
chr11_+_25596038 5.35 ENSDART00000140856
ccdc120
coiled-coil domain containing 120
chr16_-_24598042 5.20 ENSDART00000156407
ENSDART00000154072
si:dkey-56f14.4
si:dkey-56f14.4
chr2_+_16780643 5.20 ENSDART00000125647
ENSDART00000108611
ENSDART00000181245
ENSDART00000163194
tfa
transferrin-a
chr1_-_20928772 5.11 ENSDART00000078277
msmo1
methylsterol monooxygenase 1
chr2_+_24177006 4.98 ENSDART00000132582
map4l
microtubule associated protein 4 like
chr16_-_22006996 4.97 ENSDART00000116114
si:dkey-71b5.7
si:dkey-71b5.7
chr5_-_35301800 4.55 ENSDART00000085142
map1b
microtubule-associated protein 1B
chr19_+_26718074 4.52 ENSDART00000134455
zgc:100906
zgc:100906
chr8_-_14050758 4.42 ENSDART00000133922
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr9_+_32978302 4.30 ENSDART00000007630
nhlh2
nescient helix loop helix 2
chr11_+_39672874 4.21 ENSDART00000046663
ENSDART00000157659
camta1b
calmodulin binding transcription activator 1b
chr10_+_21650828 4.09 ENSDART00000160754
pcdh1g1
protocadherin 1 gamma 1
chr11_+_30513656 4.07 ENSDART00000008594
tmem178
transmembrane protein 178
chr13_-_11644806 4.03 ENSDART00000169953
dctn1b
dynactin 1b
chr2_-_40135942 3.83 ENSDART00000176951
ENSDART00000098632
ENSDART00000148563
ENSDART00000149895
epha4a
eph receptor A4a
chr1_-_14234076 3.81 ENSDART00000040049
camk2d2
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr2_+_24177190 3.72 ENSDART00000099546
map4l
microtubule associated protein 4 like
chr9_+_17984358 3.48 ENSDART00000192399
akap11
A kinase (PRKA) anchor protein 11
chr5_+_66353750 3.41 ENSDART00000143410
si:ch211-261c8.5
si:ch211-261c8.5
chr16_-_15988320 3.30 ENSDART00000160883
CABZ01060453.1

chr13_-_40499296 3.24 ENSDART00000158338
CNNM1
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr3_-_18710009 3.19 ENSDART00000142478
grid2ipa
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a
chr21_+_11401247 3.13 ENSDART00000143952
cel.1
carboxyl ester lipase, tandem duplicate 1
chr13_+_13693722 3.11 ENSDART00000110509
si:ch211-194c3.5
si:ch211-194c3.5
chr5_-_38342992 3.03 ENSDART00000140337
mink1
misshapen-like kinase 1
chr4_+_14957360 3.03 ENSDART00000002770
ENSDART00000111882
ENSDART00000148292
tspan33a
tetraspanin 33a
chr19_-_21832441 3.02 ENSDART00000151272
ENSDART00000151442
ENSDART00000150168
ENSDART00000148797
ENSDART00000128196
ENSDART00000149259
ENSDART00000052556
ENSDART00000149658
ENSDART00000149639
ENSDART00000148424
mbpa
myelin basic protein a
chr4_+_28374628 3.01 ENSDART00000076037
alg10
asparagine-linked glycosylation 10
chr15_-_20949692 2.93 ENSDART00000185548
tbcela
tubulin folding cofactor E-like a
chr12_+_26632448 2.86 ENSDART00000185762
arhgap12b
Rho GTPase activating protein 12b
chr1_+_16397063 2.83 ENSDART00000159794
micu3a
mitochondrial calcium uptake family, member 3a
chr5_+_26795465 2.82 ENSDART00000053001
tcn2
transcobalamin II
chr11_-_1409236 2.78 ENSDART00000121537
si:ch211-266k22.6
si:ch211-266k22.6
chr6_+_4229360 2.77 ENSDART00000191347
ENSDART00000130642
FO082877.1

chr16_+_36768674 2.71 ENSDART00000169208
ENSDART00000180470
si:ch73-215d9.1
si:ch73-215d9.1
chr5_-_26118855 2.70 ENSDART00000009028
ela3l
elastase 3 like
chr20_-_26039841 2.69 ENSDART00000179929
si:dkey-12h9.6
si:dkey-12h9.6
chr8_-_39978767 2.68 ENSDART00000083066
asphd2
aspartate beta-hydroxylase domain containing 2
chr1_+_10003193 2.68 ENSDART00000162675
trim2b
tripartite motif containing 2b
chr8_-_50888806 2.62 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr3_+_18807524 2.57 ENSDART00000055757
tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr17_-_43558494 2.50 ENSDART00000103830
nt5c1ab
5'-nucleotidase, cytosolic IAb
chr6_+_39812475 2.48 ENSDART00000067063
c1ql4b
complement component 1, q subcomponent-like 4b
chr1_+_26445615 2.46 ENSDART00000180810
g3bp2
GTPase activating protein (SH3 domain) binding protein 2
chr5_-_67911111 2.44 ENSDART00000051833
gsx1
GS homeobox 1
chr23_+_40460333 2.44 ENSDART00000184658
soga3b
SOGA family member 3b
chr23_-_17657348 2.43 ENSDART00000054736
bhlhe23
basic helix-loop-helix family, member e23
chr19_-_31402429 2.42 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr19_-_42588510 2.39 ENSDART00000102583
sytl1
synaptotagmin-like 1
chr18_-_26811959 2.39 ENSDART00000086250
znf592
zinc finger protein 592
chr21_+_26389391 2.39 ENSDART00000077197
tmsb
thymosin, beta
chr20_-_47731768 2.27 ENSDART00000031167
tfap2d
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr6_-_57539141 2.25 ENSDART00000156967
itcha
itchy E3 ubiquitin protein ligase a
chr10_-_24659822 2.21 ENSDART00000171842
ENSDART00000163102
proser1
proline and serine rich 1
chr22_-_17606575 2.21 ENSDART00000183951
gpx4a
glutathione peroxidase 4a
chr4_-_16706776 2.18 ENSDART00000079461
dennd5b
DENN/MADD domain containing 5B
chr16_+_40217043 2.17 ENSDART00000191128
BX470182.1

chr16_-_52540056 2.17 ENSDART00000188304
CR293507.1

chr19_+_23919096 2.16 ENSDART00000090200
snapin
SNAP-associated protein
chr15_-_15357178 2.15 ENSDART00000106120
ywhag2
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2
chr22_+_3238474 2.13 ENSDART00000157954
si:ch1073-178p5.3
si:ch1073-178p5.3
chr20_+_19793620 2.12 ENSDART00000136317
chrna2b
cholinergic receptor, nicotinic, alpha 2b (neuronal)
chr18_+_30028637 2.12 ENSDART00000139750
si:ch211-220f16.1
si:ch211-220f16.1
chr2_-_1569250 2.06 ENSDART00000167202
dab1b
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr15_+_16908085 2.04 ENSDART00000186870
ypel2b
yippee-like 2b
chr19_+_10592778 2.04 ENSDART00000135488
ENSDART00000151624
si:dkey-211g8.5
si:dkey-211g8.5
chr9_-_29985390 2.03 ENSDART00000134157
il1rapl1a
interleukin 1 receptor accessory protein-like 1a
chr13_-_25198025 1.98 ENSDART00000159585
ENSDART00000144227
adka
adenosine kinase a
chr23_+_11669109 1.94 ENSDART00000091416
cntn3a.1
contactin 3a, tandem duplicate 1
chr14_-_2187202 1.93 ENSDART00000160205
pcdh2ab12
protocadherin 2 alpha b 12
chr12_-_18408566 1.92 ENSDART00000078767
ENSDART00000152748
tom1l2
target of myb1 like 2 membrane trafficking protein
chr7_-_40145097 1.92 ENSDART00000173634
wdr60
WD repeat domain 60
chr17_+_33340675 1.91 ENSDART00000184396
ENSDART00000077553
xdh
xanthine dehydrogenase
chr1_+_26444986 1.90 ENSDART00000046376
g3bp2
GTPase activating protein (SH3 domain) binding protein 2
chr11_-_25733910 1.90 ENSDART00000171935
brpf3a
bromodomain and PHD finger containing, 3a
chr10_-_41907213 1.86 ENSDART00000167004
kdm2bb
lysine (K)-specific demethylase 2Bb
chr20_+_50852356 1.85 ENSDART00000167517
ENSDART00000168396
gphnb
gephyrin b
chr16_-_43233509 1.83 ENSDART00000025877
cldn12
claudin 12
chr9_-_18568927 1.81 ENSDART00000084668
enox1
ecto-NOX disulfide-thiol exchanger 1
chr9_+_29431763 1.79 ENSDART00000186095
ENSDART00000182640
uggt2
UDP-glucose glycoprotein glucosyltransferase 2
chr5_-_57528943 1.72 ENSDART00000130320
pisd
phosphatidylserine decarboxylase
chr11_-_30158191 1.72 ENSDART00000155278
ENSDART00000156121
scml2
Scm polycomb group protein like 2
chr10_-_7857494 1.70 ENSDART00000143215
inpp5ja
inositol polyphosphate-5-phosphatase Ja
chr2_+_26240631 1.66 ENSDART00000129895
palm1b
paralemmin 1b
chr25_-_29087925 1.66 ENSDART00000171758
rpp25a
ribonuclease P and MRP subunit p25, a
chr9_+_38883388 1.65 ENSDART00000135902
map2
microtubule-associated protein 2
chr20_-_14718801 1.62 ENSDART00000137605
suco
SUN domain containing ossification factor
chr20_+_33519435 1.57 ENSDART00000061829
drc1
dynein regulatory complex subunit 1 homolog (Chlamydomonas)
chr5_-_2672492 1.56 ENSDART00000192337
CABZ01072548.1

chr1_-_22512063 1.52 ENSDART00000031546
ENSDART00000190987
chrna6
cholinergic receptor, nicotinic, alpha 6
chr11_+_23760470 1.52 ENSDART00000175688
ENSDART00000121874
ENSDART00000086720
nfasca
neurofascin homolog (chicken) a
chr5_-_26795438 1.49 ENSDART00000146124
si:ch211-102c2.7
si:ch211-102c2.7
chr18_-_16392229 1.49 ENSDART00000189031
mgat4c
mgat4 family, member C
chr25_-_20691609 1.47 ENSDART00000186942
edc3
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
chr3_+_19299309 1.47 ENSDART00000046297
ENSDART00000146955
ldlra
low density lipoprotein receptor a
chr5_-_37871526 1.46 ENSDART00000136450
arhgap35b
Rho GTPase activating protein 35b
chr23_+_4226341 1.45 ENSDART00000012445
zgc:113278
zgc:113278
chr2_+_22659787 1.45 ENSDART00000043956
zgc:161973
zgc:161973
chr7_+_48297842 1.44 ENSDART00000052123
slc25a44b
solute carrier family 25, member 44 b
chr8_+_28358161 1.43 ENSDART00000062682
adipor1b
adiponectin receptor 1b
chr5_-_24869213 1.42 ENSDART00000112287
ENSDART00000144635
gas2l1
growth arrest-specific 2 like 1
chr7_+_54642005 1.40 ENSDART00000171864
fgf19
fibroblast growth factor 19
chr15_-_40267485 1.39 ENSDART00000152253
kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr11_+_16153207 1.37 ENSDART00000192356
tada3l
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr11_-_25734417 1.35 ENSDART00000103570
brpf3a
bromodomain and PHD finger containing, 3a
chr12_+_14676349 1.33 ENSDART00000143401
becn1
beclin 1, autophagy related
chr23_-_24234371 1.31 ENSDART00000124539
ddost
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr8_-_1838315 1.31 ENSDART00000114476
ENSDART00000140077
pi4kab
phosphatidylinositol 4-kinase, catalytic, alpha b
chr20_+_44311448 1.30 ENSDART00000114660
opn8b
opsin 8, group member b
chr19_-_9522548 1.28 ENSDART00000045245
ing4
inhibitor of growth family, member 4
chr23_-_25126003 1.26 ENSDART00000034953
idh3g
isocitrate dehydrogenase 3 (NAD+) gamma
chr5_+_61657010 1.24 ENSDART00000050916
ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr22_+_7439186 1.23 ENSDART00000190667
zgc:92041
zgc:92041
chr10_+_42521943 1.22 ENSDART00000010420
ENSDART00000075303
actr1
ARP1 actin related protein 1, centractin
chr22_-_6219674 1.19 ENSDART00000182582
si:ch211-274k16.2
si:ch211-274k16.2
chr5_+_63857055 1.17 ENSDART00000138950
rgs3b
regulator of G protein signaling 3b
chrM_+_12897 1.17 ENSDART00000093622
mt-nd5
NADH dehydrogenase 5, mitochondrial
chr11_-_16093018 1.13 ENSDART00000139309
ENSDART00000139819
SPATA1
si:dkey-205k8.5
chr9_+_29520696 1.13 ENSDART00000144430
fdx1
ferredoxin 1
chr11_+_41243094 1.11 ENSDART00000191782
ENSDART00000169817
ENSDART00000162157
pax7a
paired box 7a
chr5_+_24543862 1.08 ENSDART00000029699
atp6v0a2b
ATPase H+ transporting V0 subunit a2b
chr20_+_54383838 1.07 ENSDART00000157737
lrfn5b
leucine rich repeat and fibronectin type III domain containing 5b
chr24_-_38657683 1.07 ENSDART00000154843
si:ch1073-164k15.3
si:ch1073-164k15.3
chr10_-_28761454 1.04 ENSDART00000129400
alcama
activated leukocyte cell adhesion molecule a
chr22_+_7462997 0.96 ENSDART00000106082
zgc:112368
zgc:112368
chr19_-_18135724 0.96 ENSDART00000186609
cbx3a
chromobox homolog 3a (HP1 gamma homolog, Drosophila)
chr19_-_6083761 0.96 ENSDART00000151185
ENSDART00000143941
gsk3aa
glycogen synthase kinase 3 alpha a
chr6_-_27108844 0.94 ENSDART00000073883
dtymk
deoxythymidylate kinase (thymidylate kinase)
chr21_-_21530868 0.92 ENSDART00000174231
or133-9
odorant receptor, family H, subfamily 133, member 9
chr6_-_1768724 0.89 ENSDART00000162488
ENSDART00000163613
zgc:158417
zgc:158417
chr15_-_14467394 0.88 ENSDART00000191944
numbl
numb homolog (Drosophila)-like
chr19_-_17864213 0.88 ENSDART00000151043
ints8
integrator complex subunit 8
chr9_+_32859967 0.88 ENSDART00000168992
si:dkey-145p14.5
si:dkey-145p14.5
chr5_-_24543526 0.87 ENSDART00000046384
trmt2a
tRNA methyltransferase 2 homolog A
chr20_+_50115335 0.86 ENSDART00000031139
slc24a4b
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4b
chr21_-_18648861 0.86 ENSDART00000112113
si:dkey-112m2.1
si:dkey-112m2.1
chr12_-_15567104 0.85 ENSDART00000053003
hexim1
hexamethylene bis-acetamide inducible 1
chr10_+_17714866 0.85 ENSDART00000039969
slc20a1b
solute carrier family 20 (phosphate transporter), member 1b
chr11_+_13024002 0.84 ENSDART00000104113
btf3l4
basic transcription factor 3-like 4
chr8_-_45867358 0.84 ENSDART00000132810
adam9
ADAM metallopeptidase domain 9
chr20_+_41664350 0.82 ENSDART00000186247
fam184a
family with sequence similarity 184, member A
chr6_-_15492030 0.82 ENSDART00000156141
ENSDART00000183992
st6gal2b
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2b
chr5_+_3118231 0.81 ENSDART00000179809
supt4h1
SPT4 homolog, DSIF elongation factor subunit
chr25_-_7764083 0.81 ENSDART00000179800
ENSDART00000181858
phf21ab
PHD finger protein 21Ab
chr21_+_42930558 0.80 ENSDART00000135234
stk32a
serine/threonine kinase 32A
chr5_+_41996889 0.80 ENSDART00000097580
pigl
phosphatidylinositol glycan anchor biosynthesis, class L
chr10_+_38806719 0.79 ENSDART00000184416
dscama
Down syndrome cell adhesion molecule a
chr10_-_27009413 0.79 ENSDART00000139942
ENSDART00000146983
ENSDART00000132352
uqcc3
ubiquinol-cytochrome c reductase complex assembly factor 3
chr22_-_10440688 0.76 ENSDART00000111962
nol8
nucleolar protein 8
chr5_-_13251907 0.75 ENSDART00000176774
ENSDART00000030553
top3b
DNA topoisomerase III beta
chr2_+_9061885 0.72 ENSDART00000028906
pigk
phosphatidylinositol glycan anchor biosynthesis, class K
chr6_-_31336317 0.72 ENSDART00000193927
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr21_+_26612777 0.71 ENSDART00000142667
esrra
estrogen-related receptor alpha
chr4_-_25859305 0.70 ENSDART00000159528
nr2c1
nuclear receptor subfamily 2, group C, member 1
chr22_+_6674992 0.68 ENSDART00000144054
si:ch211-209l18.2
si:ch211-209l18.2
chr14_-_17576662 0.68 ENSDART00000193893
rnf4
ring finger protein 4
chr8_-_39822917 0.67 ENSDART00000067843
zgc:162025
zgc:162025
chr10_+_17713022 0.62 ENSDART00000170453
slc20a1b
solute carrier family 20 (phosphate transporter), member 1b
chr2_+_47906240 0.61 ENSDART00000122206
ftr23
finTRIM family, member 23
chr22_+_10440991 0.60 ENSDART00000064805
cenpp
centromere protein P
chr17_-_43031763 0.60 ENSDART00000132754
ENSDART00000050399
npc2
Niemann-Pick disease, type C2
chr2_-_30055432 0.60 ENSDART00000056747
shhb
sonic hedgehog b
chr21_-_40317035 0.59 ENSDART00000143648
ENSDART00000013359
or101-1
odorant receptor, family B, subfamily 101, member 1
chr8_+_13368150 0.56 ENSDART00000114699
slc5a5
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr18_+_3579829 0.52 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr17_+_12658411 0.52 ENSDART00000139918
gpn1
GPN-loop GTPase 1
chr25_-_20378721 0.52 ENSDART00000181707
kctd15a
potassium channel tetramerization domain containing 15a
chr25_+_19485198 0.51 ENSDART00000156730
glsl
glutaminase like
chr23_-_31403668 0.50 ENSDART00000147498
CR759830.1

chr1_-_23596391 0.47 ENSDART00000155184
lcorl
ligand dependent nuclear receptor corepressor-like
chr12_+_32323098 0.47 ENSDART00000188722
ANKFN1
si:ch211-277e21.2
chr19_+_2279051 0.46 ENSDART00000182103
itgb8
integrin, beta 8
chr10_+_2587234 0.46 ENSDART00000126937
wu:fb59d01
wu:fb59d01
chr1_+_21309386 0.45 ENSDART00000054442
ENSDART00000145661
med28
mediator complex subunit 28
chr10_+_24660017 0.45 ENSDART00000079597
vps36
vacuolar protein sorting 36 homolog (S. cerevisiae)
chr7_+_19762595 0.44 ENSDART00000130347
si:dkey-9k7.3
si:dkey-9k7.3
chr4_-_18635005 0.43 ENSDART00000125361
pparaa
peroxisome proliferator-activated receptor alpha a
chr4_-_52165969 0.42 ENSDART00000171130
si:dkeyp-44b5.4
si:dkeyp-44b5.4
chr2_-_37532772 0.42 ENSDART00000133951
arhgef18a
rho/rac guanine nucleotide exchange factor (GEF) 18a
chr11_-_891674 0.42 ENSDART00000172904
atg7
ATG7 autophagy related 7 homolog (S. cerevisiae)
chr7_+_56735195 0.41 ENSDART00000082830
KIAA0895L
KIAA0895 like
chr10_-_39321367 0.41 ENSDART00000129647
smtlb
somatolactin beta
chr17_-_27223965 0.41 ENSDART00000192577
asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr8_+_34434345 0.39 ENSDART00000190246
ENSDART00000189447
ENSDART00000185557
ENSDART00000189230
zgc:174461
zgc:174461
chr19_-_47456787 0.38 ENSDART00000168792
tfap2e
transcription factor AP-2 epsilon
chr17_+_47090497 0.35 ENSDART00000169038
ENSDART00000159292
zgc:103755
zgc:103755
chr15_-_45510977 0.35 ENSDART00000090596
fgf12b
fibroblast growth factor 12b
chr20_+_9128829 0.34 ENSDART00000064144
ENSDART00000137450
bpnt1
bisphosphate nucleotidase 1
chr10_-_41906609 0.34 ENSDART00000102530
kdm2bb
lysine (K)-specific demethylase 2Bb
chr7_+_57108823 0.33 ENSDART00000184943
ENSDART00000055956
enosf1
enolase superfamily member 1
chr4_-_59057046 0.33 ENSDART00000150249
znf1132
zinc finger protein 1132
chr3_-_32873641 0.33 ENSDART00000075277
zgc:113090
zgc:113090
chr14_+_35383267 0.32 ENSDART00000143818
clint1a
clathrin interactor 1a
chr22_-_35961365 0.31 ENSDART00000188434
LO016987.2

chr19_+_32401278 0.28 ENSDART00000184353
atxn1a
ataxin 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of sox11a+sox11b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:0015824 proline transport(GO:0015824)
1.4 4.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.9 2.8 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.7 7.6 GO:0019731 antibacterial humoral response(GO:0019731)
0.6 1.9 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.6 1.9 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.5 3.8 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.5 2.7 GO:0023041 neuronal signal transduction(GO:0023041)
0.4 1.3 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.4 8.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 1.8 GO:0007624 ultradian rhythm(GO:0007624)
0.3 1.4 GO:0051876 pigment granule dispersal(GO:0051876)
0.3 2.1 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.3 2.0 GO:0044209 AMP salvage(GO:0044209)
0.3 4.5 GO:0001840 neural plate development(GO:0001840)
0.3 0.9 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.3 3.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.3 3.1 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.3 1.1 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.3 2.9 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.3 4.5 GO:0032418 lysosome localization(GO:0032418)
0.2 1.5 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 1.9 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.2 3.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.2 7.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 1.1 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.2 1.7 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.2 1.6 GO:0046850 regulation of bone remodeling(GO:0046850)
0.2 1.6 GO:0003352 regulation of cilium movement(GO:0003352)
0.2 2.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 1.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 2.3 GO:0016540 protein autoprocessing(GO:0016540)
0.2 2.1 GO:0035094 response to nicotine(GO:0035094)
0.2 3.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.2 2.2 GO:0009303 rRNA transcription(GO:0009303)
0.2 1.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.2 2.8 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2 4.0 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 1.5 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 1.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 1.1 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.1 0.7 GO:0097065 anterior head development(GO:0097065)
0.1 0.8 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 2.0 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.1 0.8 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.7 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 5.1 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 2.6 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.6 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 2.7 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 3.0 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 0.3 GO:2000434 regulation of protein neddylation(GO:2000434)
0.1 1.4 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.1 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 0.4 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 2.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.5 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 1.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 1.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 0.4 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 1.9 GO:0042073 intraciliary transport(GO:0042073)
0.1 0.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.4 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.4 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 1.4 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.8 GO:0006265 DNA topological change(GO:0006265)
0.0 1.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 3.3 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.8 GO:0060324 face development(GO:0060324)
0.0 1.0 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.9 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.8 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 1.0 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.9 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 1.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 6.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 1.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.3 GO:0045682 regulation of epidermis development(GO:0045682)
0.0 1.5 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.3 GO:0016573 histone acetylation(GO:0016573)
0.0 2.4 GO:0010506 regulation of autophagy(GO:0010506)
0.0 3.0 GO:0051604 protein maturation(GO:0051604)
0.0 0.7 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 8.8 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 0.2 GO:0003139 secondary heart field specification(GO:0003139)
0.0 1.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.5 GO:0042552 myelination(GO:0042552)
0.0 4.1 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 2.7 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.1 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 1.4 GO:0008360 regulation of cell shape(GO:0008360)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0032044 DSIF complex(GO:0032044)
0.3 1.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.2 1.7 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 2.8 GO:1990246 uniplex complex(GO:1990246)
0.2 3.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 4.4 GO:0035371 microtubule plus-end(GO:0035371)
0.2 3.0 GO:0043209 myelin sheath(GO:0043209)
0.2 1.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 1.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.7 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 2.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 1.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 2.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.5 GO:0000814 ESCRT II complex(GO:0000814)
0.1 1.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 1.6 GO:0005858 axonemal dynein complex(GO:0005858)
0.1 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 5.2 GO:0055037 recycling endosome(GO:0055037)
0.0 16.3 GO:0005874 microtubule(GO:0005874)
0.0 1.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.9 GO:0032039 integrator complex(GO:0032039)
0.0 1.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 2.4 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 3.1 GO:0005769 early endosome(GO:0005769)
0.0 1.2 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 3.7 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 5.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 4.4 GO:0005768 endosome(GO:0005768)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 7.4 GO:0009986 cell surface(GO:0009986)
0.0 16.3 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.5 GO:0070382 exocytic vesicle(GO:0070382)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0004771 sterol esterase activity(GO:0004771)
0.7 5.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.7 2.0 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.6 1.9 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.5 7.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.5 1.5 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.4 2.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.4 2.0 GO:0004001 adenosine kinase activity(GO:0004001)
0.4 1.5 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.4 1.8 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.4 2.8 GO:0031419 cobalamin binding(GO:0031419)
0.3 0.9 GO:0009041 uridylate kinase activity(GO:0009041)
0.3 0.8 GO:1901612 cardiolipin binding(GO:1901612)
0.3 1.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2 2.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 2.6 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 3.2 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.2 3.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 1.7 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.2 1.9 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.2 3.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 4.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 2.6 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 1.8 GO:0045503 dynein light chain binding(GO:0045503)
0.1 0.4 GO:0005131 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.1 4.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.0 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 2.4 GO:0003785 actin monomer binding(GO:0003785)
0.1 2.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.8 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.5 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.9 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 1.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.4 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 2.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 3.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.2 GO:0008252 nucleotidase activity(GO:0008252)
0.1 1.1 GO:0051117 ATPase binding(GO:0051117)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.6 GO:0005113 patched binding(GO:0005113)
0.1 0.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 1.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 17.8 GO:0008017 microtubule binding(GO:0008017)
0.0 1.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 1.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 4.2 GO:0030276 clathrin binding(GO:0030276)
0.0 7.4 GO:0015293 symporter activity(GO:0015293)
0.0 1.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 5.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.1 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.5 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.9 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 4.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.6 GO:0015485 cholesterol binding(GO:0015485)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.5 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.4 PID FGF PATHWAY FGF signaling pathway
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.9 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 5.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 1.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 1.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 1.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 1.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 3.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 1.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.8 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 4.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase