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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for sox14+sox14-1+sox21a

Z-value: 0.89

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Transcription factors associated with sox14+sox14-1+sox21a

Gene Symbol Gene ID Gene Info
sox21a
ENSDARG00000031664 SRY-box transcription factor 21a
sox14
ENSDARG00000070929 SRY-box transcription factor 14
sox21a
ENSDARG00000111842 SRY-box transcription factor 21a
sox14-1
ENSDARG00000111969 SRY-box transcription factor 14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox14dr11_v1_chr6_-_26559921_26559921-0.528.2e-08Click!
FQ377628.2dr11_v1_chr2_-_22575851_22575851-0.405.9e-05Click!
sox21adr11_v1_chr6_+_7414215_7414215-0.141.8e-01Click!

Activity profile of sox14+sox14-1+sox21a motif

Sorted Z-values of sox14+sox14-1+sox21a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_11457500 15.83 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr24_-_11076400 11.53 ENSDART00000003195
chmp4c
charged multivesicular body protein 4C
chr12_-_4346085 9.75 ENSDART00000112433
ca15c
carbonic anhydrase XV c
chr16_-_51888952 8.71 ENSDART00000186407
ENSDART00000175435
rpl28
ribosomal protein L28
chr15_-_21132480 8.69 ENSDART00000078734
ENSDART00000157481
a2ml
alpha-2-macroglobulin-like
chr17_+_53292215 7.87 ENSDART00000170686
si:ch1073-416d2.3
si:ch1073-416d2.3
chr5_-_41531629 7.36 ENSDART00000051082
akr1a1a
aldo-keto reductase family 1, member A1a (aldehyde reductase)
chr6_+_7466223 7.00 ENSDART00000148908
erbb3a
erb-b2 receptor tyrosine kinase 3a
chr3_-_50139860 6.60 ENSDART00000101563
btr02
bloodthirsty-related gene family, member 2
chr23_+_42819221 6.50 ENSDART00000180495
myl9a
myosin, light chain 9a, regulatory
chr2_-_56348727 6.27 ENSDART00000060745
uba52
ubiquitin A-52 residue ribosomal protein fusion product 1
chr23_-_19715799 6.20 ENSDART00000142072
ENSDART00000032744
ENSDART00000131860
rpl10
ribosomal protein L10
chr1_-_49225890 6.09 ENSDART00000111598
cxcl18b
chemokine (C-X-C motif) ligand 18b
chr25_-_13023569 5.98 ENSDART00000167232
ccl39.1
chemokine (C-C motif) ligand 39, duplicate 1
chr1_+_59088205 5.73 ENSDART00000150649
ENSDART00000100197
zgc:173915
zgc:173915
chr6_-_39764995 5.73 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr8_-_45760087 5.67 ENSDART00000025620
ppiaa
peptidylprolyl isomerase Aa (cyclophilin A)
chr5_-_30615901 5.64 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr7_+_35268880 5.44 ENSDART00000182231
dpep2
dipeptidase 2
chr12_+_22576404 5.33 ENSDART00000172053
capgb
capping protein (actin filament), gelsolin-like b
chr23_+_10352921 5.26 ENSDART00000081193
KRT18 (1 of many)
si:ch211-133j6.3
chr14_+_46313135 5.21 ENSDART00000172902
cryba1l1
crystallin, beta A1, like 1
chr9_-_23922011 5.13 ENSDART00000145734
col6a3
collagen, type VI, alpha 3
chr24_-_40700596 5.00 ENSDART00000162635
smyhc2
slow myosin heavy chain 2
chr19_-_7420867 4.99 ENSDART00000081741
rab25a
RAB25, member RAS oncogene family a
chr1_+_218524 4.73 ENSDART00000109529
tmco3
transmembrane and coiled-coil domains 3
chr2_-_39017838 4.65 ENSDART00000048838
rbp2b
retinol binding protein 2b, cellular
chr7_+_31891110 4.63 ENSDART00000173883
mybpc3
myosin binding protein C, cardiac
chr6_+_584632 4.62 ENSDART00000151150
zgc:92360
zgc:92360
chr8_-_32385989 4.51 ENSDART00000143716
ENSDART00000098850
lipg
lipase, endothelial
chr14_+_46313396 4.45 ENSDART00000047525
cryba1l1
crystallin, beta A1, like 1
chr15_+_22390076 4.42 ENSDART00000183764
oafa
OAF homolog a (Drosophila)
chr7_+_38380135 4.35 ENSDART00000174005
rhpn2
rhophilin, Rho GTPase binding protein 2
chr6_-_39765546 4.34 ENSDART00000185767
pfkmb
phosphofructokinase, muscle b
chr9_-_23922778 4.28 ENSDART00000135769
col6a3
collagen, type VI, alpha 3
chr25_-_12982193 4.25 ENSDART00000159617
ccl39.5
chemokine (C-C motif) ligand 39, duplicate 5
chr3_-_34069637 4.18 ENSDART00000151588
ighv9-1
immunoglobulin heavy variable 9-1
chr20_+_54312970 4.15 ENSDART00000024598
ENSDART00000193172
zp2.5
zona pellucida glycoprotein 2, tandem duplicate 5
chr10_+_33171501 4.09 ENSDART00000159666
myl10
myosin, light chain 10, regulatory
chr22_-_15693085 4.03 ENSDART00000141861
si:ch1073-396h14.1
si:ch1073-396h14.1
chr16_-_17056630 4.03 ENSDART00000138715
plekhg6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr15_+_37331585 4.03 ENSDART00000170715
zgc:171592
zgc:171592
chr23_+_42813415 4.01 ENSDART00000055577
myl9a
myosin, light chain 9a, regulatory
chr12_-_33770299 3.99 ENSDART00000189849
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr12_-_2800809 3.96 ENSDART00000152682
ENSDART00000083784
ubtd1b
ubiquitin domain containing 1b
chr8_-_30204650 3.94 ENSDART00000133209
zgc:162939
zgc:162939
chr15_-_36533322 3.84 ENSDART00000156466
ENSDART00000121755
si:dkey-262k9.4
si:dkey-262k9.4
chr23_-_3758637 3.82 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
hmga1a
high mobility group AT-hook 1a
chr12_-_17655683 3.77 ENSDART00000066411
dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr9_-_21838045 3.76 ENSDART00000147471
acod1
aconitate decarboxylase 1
chr18_+_46151505 3.76 ENSDART00000015034
ENSDART00000141287
blvrb
biliverdin reductase B
chr8_-_46486009 3.74 ENSDART00000140431
sult1st9
sulfotransferase family 1, cytosolic sulfotransferase 9
chr21_+_21621042 3.69 ENSDART00000134907
tgfb1b
transforming growth factor, beta 1b
chr22_+_30631072 3.59 ENSDART00000059970
zmp:0000000606
zmp:0000000606
chr3_+_3545825 3.57 ENSDART00000109060
CR589947.1

chr23_-_6641223 3.52 ENSDART00000023793
mipb
major intrinsic protein of lens fiber b
chr21_-_44081540 3.50 ENSDART00000130833
FO704810.1

chr2_+_36004381 3.41 ENSDART00000098706
lamc2
laminin, gamma 2
chr14_-_970853 3.41 ENSDART00000130801
acsl1b
acyl-CoA synthetase long chain family member 1b
chr6_+_30668098 3.33 ENSDART00000112294
ttc22
tetratricopeptide repeat domain 22
chr23_+_19213472 3.32 ENSDART00000185985
apobec2b
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2b
chr5_-_57686487 3.16 ENSDART00000074264
crfb12
cytokine receptor family member B12
chr5_-_26181863 3.13 ENSDART00000098500
ccdc125
coiled-coil domain containing 125
chr10_-_342564 3.11 ENSDART00000157633
vaspa
vasodilator stimulated phosphoprotein a
chr16_-_21799407 3.04 ENSDART00000123717
FP015862.4

chr14_-_38872536 2.98 ENSDART00000184315
ENSDART00000127479
gsr
glutathione reductase
chr11_+_29965822 2.98 ENSDART00000127049
il1fma
interleukin-1 family member A
chr20_+_54309148 2.95 ENSDART00000099360
zp2.1
zona pellucida glycoprotein 2, tandem duplicate 1
chr7_-_19915414 2.91 ENSDART00000144180
zgc:110591
zgc:110591
chr25_+_25202213 2.84 ENSDART00000150744
ccl39a.10
chemokine (C-C motif) ligand 39, duplicate 10
chr1_+_32051581 2.84 ENSDART00000146602
sts
steroid sulfatase (microsomal), isozyme S
chr22_-_24967348 2.81 ENSDART00000153490
ENSDART00000084871
fam20cl
family with sequence similarity 20, member C like
chr14_-_246342 2.80 ENSDART00000054823
aurkb
aurora kinase B
chr5_+_38680247 2.78 ENSDART00000132763
si:dkey-58f10.11
si:dkey-58f10.11
chr20_+_54299419 2.75 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
si:zfos-1505d6.3
chr16_-_41487589 2.73 ENSDART00000188115
cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr16_+_35535375 2.71 ENSDART00000171675
cited4b
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr20_+_9128829 2.71 ENSDART00000064144
ENSDART00000137450
bpnt1
bisphosphate nucleotidase 1
chr3_+_41714966 2.69 ENSDART00000155440
eif3ba
eukaryotic translation initiation factor 3, subunit Ba
chr19_+_43716607 2.68 ENSDART00000133199
cap1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr20_+_54295213 2.60 ENSDART00000074085
zp2.3
zona pellucida glycoprotein 2, tandem duplicate 3
chr15_+_29025090 2.59 ENSDART00000131755
si:ch211-137a8.2
si:ch211-137a8.2
chr11_-_24063196 2.57 ENSDART00000036513
trib3
tribbles pseudokinase 3
chr19_+_43715911 2.56 ENSDART00000006344
cap1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr15_+_11644866 2.55 ENSDART00000188716
slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr10_+_24692076 2.53 ENSDART00000181600
tpte
transmembrane phosphatase with tensin homology
chr2_-_51512294 2.52 ENSDART00000185287
si:ch211-9d9.8
si:ch211-9d9.8
chr9_-_24244383 2.50 ENSDART00000182407
cavin2a
caveolae associated protein 2a
chr24_-_26484298 2.44 ENSDART00000140647
eif5a
eukaryotic translation initiation factor 5A
chr6_+_12968101 2.39 ENSDART00000013781
mcm6
minichromosome maintenance complex component 6
chr17_+_2727807 2.37 ENSDART00000178759
kcnk10b
potassium channel, subfamily K, member 10b
chr16_-_41488023 2.33 ENSDART00000169312
cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr11_+_14280598 2.29 ENSDART00000163033
si:ch211-262i1.3
si:ch211-262i1.3
chr2_+_36608387 2.28 ENSDART00000159541
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr14_-_38873095 2.24 ENSDART00000047050
ENSDART00000173285
ENSDART00000147521
gsr
glutathione reductase
chr16_+_28578648 2.23 ENSDART00000149566
nmt2
N-myristoyltransferase 2
chr13_-_25819825 2.23 ENSDART00000077612
rel
v-rel avian reticuloendotheliosis viral oncogene homolog
chr20_+_9128256 2.23 ENSDART00000163883
ENSDART00000183072
ENSDART00000187276
bpnt1
bisphosphate nucleotidase 1
chr2_-_45510699 2.21 ENSDART00000024034
ENSDART00000145634
gpsm2
G protein signaling modulator 2
chr6_-_40885496 2.18 ENSDART00000189857
sirt4
sirtuin 4
chr2_-_51500957 2.17 ENSDART00000172481
pigrl3.5
polymeric immunoglobulin receptor-like 3.5
chr17_-_6600899 2.17 ENSDART00000154074
ENSDART00000180912
ANKRD66
si:ch211-189e2.2
chr7_+_9922607 2.16 ENSDART00000184532
ENSDART00000113396
cers3a
ceramide synthase 3a
chr3_+_53240562 2.14 ENSDART00000031234
stxbp2
syntaxin binding protein 2
chr20_+_27749133 2.14 ENSDART00000089013
vrtn
vertebrae development associated
chr8_-_20243389 2.12 ENSDART00000184904
acer1
alkaline ceramidase 1
chr3_-_5644028 2.09 ENSDART00000019957
ddx39ab
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Ab
chr22_-_23781083 2.09 ENSDART00000166563
ENSDART00000170458
ENSDART00000166158
ENSDART00000171246
cfhl3
complement factor H like 3
chr25_+_32474031 2.08 ENSDART00000152124
sqor
sulfide quinone oxidoreductase
chr9_-_23152092 2.03 ENSDART00000180155
ENSDART00000186935
lypd6b
LY6/PLAUR domain containing 6B
chr22_+_4443689 2.02 ENSDART00000185490
ticam1
toll-like receptor adaptor molecule 1
chr21_+_37436907 2.00 ENSDART00000182611
ENSDART00000076328
pgrmc1
progesterone receptor membrane component 1
chr8_-_46457233 2.00 ENSDART00000113214
sult1st7
sulfotransferase family 1, cytosolic sulfotransferase 7
chr14_+_26439227 2.00 ENSDART00000054183
gpr137
G protein-coupled receptor 137
chr25_-_12805295 1.95 ENSDART00000157629
ca5a
carbonic anhydrase Va
chr3_-_59297532 1.92 ENSDART00000187991
CABZ01053748.1

chr20_+_32152355 1.89 ENSDART00000152904
ENSDART00000139507
sesn1
sestrin 1
chr7_+_8324506 1.86 ENSDART00000168110
si:dkey-185m8.2
si:dkey-185m8.2
chr8_+_43852743 1.85 ENSDART00000186485
AL808129.2

chr6_-_1591002 1.85 ENSDART00000087039
zgc:123305
zgc:123305
chr19_-_11949996 1.78 ENSDART00000163478
ENSDART00000167299
cpsf1
cleavage and polyadenylation specific factor 1
chr24_-_26485098 1.77 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eif5a
eukaryotic translation initiation factor 5A
chr22_+_1028724 1.77 ENSDART00000149625
si:ch73-352p18.4
si:ch73-352p18.4
chr17_-_32863250 1.76 ENSDART00000167292
prox1a
prospero homeobox 1a
chr7_+_67381912 1.73 ENSDART00000167564
nfat5b
nuclear factor of activated T cells 5b
chr12_-_44010532 1.72 ENSDART00000183875
si:ch211-182p11.1
si:ch211-182p11.1
chr3_-_34054081 1.72 ENSDART00000151590
ighv1-2
immunoglobulin heavy variable 1-2
chr2_-_28420415 1.72 ENSDART00000183857
CABZ01056051.1

chr6_+_17789481 1.70 ENSDART00000190768
CR376861.1

chr1_-_55118745 1.68 ENSDART00000133915
sertad2a
SERTA domain containing 2a
chr10_+_44042033 1.68 ENSDART00000190006
ENSDART00000046172
cryba4
crystallin, beta A4
chr4_-_22749553 1.67 ENSDART00000040033
nup107
nucleoporin 107
chr4_+_69262318 1.64 ENSDART00000188841
si:ch211-209j12.6
si:ch211-209j12.6
chr6_-_25371196 1.62 ENSDART00000187291
PKN2 (1 of many)
zgc:153916
chr25_-_12998202 1.61 ENSDART00000171661
ccl39.3
chemokine (C-C motif) ligand 39, duplicate 3
chr9_-_11560110 1.59 ENSDART00000176941
cryba2b
crystallin, beta A2b
chr3_-_41715690 1.59 ENSDART00000184703
BX324110.1

chr7_-_57332915 1.58 ENSDART00000162653
BX470176.1

chr4_-_14470071 1.56 ENSDART00000143773
plxnb2a
plexin b2a
chr16_+_5926520 1.56 ENSDART00000162229
ulk4
unc-51 like kinase 4
chr5_+_38631687 1.55 ENSDART00000147280
si:ch211-271e10.6
si:ch211-271e10.6
chr25_+_35058088 1.53 ENSDART00000156838
zgc:112234
zgc:112234
chr12_+_19030391 1.53 ENSDART00000153927
si:ch73-139e5.2
si:ch73-139e5.2
chr17_-_44402713 1.53 ENSDART00000190343
BX548045.2

chr6_+_43426599 1.51 ENSDART00000056457
mitfa
microphthalmia-associated transcription factor a
chr5_+_38680061 1.51 ENSDART00000143259
si:dkey-58f10.11
si:dkey-58f10.11
chr23_-_27857051 1.51 ENSDART00000043462
ENSDART00000137861
acvrl1
activin A receptor like type 1
chr5_-_26834511 1.50 ENSDART00000136713
ENSDART00000192932
ENSDART00000113246
si:ch211-102c2.4
si:ch211-102c2.4
chr3_-_34068044 1.48 ENSDART00000187926
ighv10-1
immunoglobulin heavy variable 10-1
chr17_-_6599484 1.48 ENSDART00000156927
ANKRD66
si:ch211-189e2.2
chr7_-_34294613 1.45 ENSDART00000191632
CR388195.1

chr15_+_17623115 1.45 ENSDART00000062378
adamts15b
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr1_+_44780849 1.45 ENSDART00000145895
si:dkey-9i23.5
si:dkey-9i23.5
chr4_+_59748607 1.43 ENSDART00000108499
znf1068
zinc finger protein 1068
chr5_-_23715027 1.38 ENSDART00000139020
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr3_+_52078798 1.35 ENSDART00000156882
si:dkey-88e12.3
si:dkey-88e12.3
chr20_+_54036981 1.35 ENSDART00000060455
wdr20b
WD repeat domain 20b
chr8_-_23884301 1.34 ENSDART00000185509
ENSDART00000147202
lhfpl5b
LHFPL tetraspan subfamily member 5b
chr7_-_51953807 1.34 ENSDART00000174102
ENSDART00000145645
ENSDART00000052054
cyp2x10.2
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr5_-_201600 1.33 ENSDART00000158495
CABZ01088906.1

chr11_+_36665359 1.29 ENSDART00000166144
si:ch211-11c3.9
si:ch211-11c3.9
chr11_-_11791718 1.27 ENSDART00000180476
cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr4_-_68901741 1.26 ENSDART00000163087
si:dkey-264f17.5
si:dkey-264f17.5
chr13_-_38088627 1.25 ENSDART00000175268
CT027676.1

chr4_-_25796848 1.24 ENSDART00000122881
tmcc3
transmembrane and coiled-coil domain family 3
chr14_+_16036139 1.22 ENSDART00000190733
prelid1a
PRELI domain containing 1a
chr10_+_36197968 1.22 ENSDART00000114102
COA4
si:ch211-215a9.5
chr2_+_36939749 1.22 ENSDART00000005382
gadd45bb
growth arrest and DNA-damage-inducible, beta b
chr21_+_18405585 1.21 ENSDART00000139318
si:dkey-1d7.3
si:dkey-1d7.3
chr24_+_13642126 1.20 ENSDART00000126769
trpa1b
transient receptor potential cation channel, subfamily A, member 1b
chr15_+_38071874 1.20 ENSDART00000125770
si:ch73-380l3.5
si:ch73-380l3.5
chr19_-_32849036 1.20 ENSDART00000131518
si:dkey-284p5.3
si:dkey-284p5.3
chr14_+_30910114 1.18 ENSDART00000187166
ENSDART00000078187
foxo4
forkhead box O4
chr4_-_43070566 1.17 ENSDART00000183779
si:dkey-54j5.2
si:dkey-54j5.2
chr9_-_11560427 1.17 ENSDART00000127942
ENSDART00000061442
cryba2b
crystallin, beta A2b
chr9_-_2936017 1.15 ENSDART00000102823
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr9_-_39624173 1.15 ENSDART00000180106
ENSDART00000126766
erbb4b
erb-b2 receptor tyrosine kinase 4b
chr4_-_61650771 1.14 ENSDART00000168593
si:dkey-26i24.1
si:dkey-26i24.1
chr5_+_38743644 1.14 ENSDART00000137658
si:dkey-58f10.6
si:dkey-58f10.6
chr2_-_25159309 1.13 ENSDART00000137290
si:dkey-223d7.6
si:dkey-223d7.6
chr5_+_43782267 1.13 ENSDART00000130355
nos2a
nitric oxide synthase 2a, inducible
chr14_-_21238046 1.13 ENSDART00000129743
si:ch211-175m2.5
si:ch211-175m2.5
chr11_+_15821433 1.13 ENSDART00000191005
FP003590.3

chr16_-_40373836 1.10 ENSDART00000134498
si:dkey-242e21.3
si:dkey-242e21.3
chr20_-_7547080 1.10 ENSDART00000146135
usp24
ubiquitin specific peptidase 24
chr15_+_31481939 1.09 ENSDART00000134306
or102-5
odorant receptor, family C, subfamily 102, member 5
chr20_+_33922339 1.08 ENSDART00000019059
lmx1a
LIM homeobox transcription factor 1, alpha
chr15_+_38006366 1.07 ENSDART00000156162
si:dkey-238d18.13
si:dkey-238d18.13
chr13_-_36761379 1.07 ENSDART00000131534
ENSDART00000029824
map4k5
mitogen-activated protein kinase kinase kinase kinase 5
chr19_-_18418763 1.06 ENSDART00000167271
zgc:112966
zgc:112966
chr18_+_33570170 1.05 ENSDART00000133276
si:dkey-47k20.3
si:dkey-47k20.3
chr2_-_6112862 1.05 ENSDART00000164269
prdx1
peroxiredoxin 1
chr6_+_30456788 1.05 ENSDART00000121492
FP236735.1

chr5_-_66028371 1.04 ENSDART00000183012
nrarpb
NOTCH regulated ankyrin repeat protein b
chr1_-_18848955 1.03 ENSDART00000109294
ENSDART00000146410
zgc:195282
zgc:195282
chr11_+_16138065 1.02 ENSDART00000188616
pimr204
Pim proto-oncogene, serine/threonine kinase, related 204
chr25_+_34862225 0.99 ENSDART00000149782
CHST6
zgc:194879
chr3_-_10751491 0.95 ENSDART00000016351
zgc:112965
zgc:112965
chr13_+_8677166 0.95 ENSDART00000181016
ENSDART00000135028
prop1
PROP paired-like homeobox 1
chr8_+_18830759 0.94 ENSDART00000089079
mpnd
MPN domain containing

Network of associatons between targets according to the STRING database.

First level regulatory network of sox14+sox14-1+sox21a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:1990403 embryonic brain development(GO:1990403)
1.1 3.3 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.9 2.8 GO:0009838 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878) regulation of lymphocyte apoptotic process(GO:0070228)
0.9 4.6 GO:0003210 cardiac atrium formation(GO:0003210)
0.9 10.1 GO:0006007 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.9 2.7 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.8 4.0 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.7 5.0 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.7 2.8 GO:0070166 enamel mineralization(GO:0070166)
0.7 2.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.7 2.0 GO:0032816 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.6 4.2 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.6 2.2 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.6 1.7 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.5 3.8 GO:1903426 regulation of reactive oxygen species biosynthetic process(GO:1903426)
0.4 9.0 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.4 5.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.4 1.2 GO:0007635 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.4 3.5 GO:0006833 water transport(GO:0006833)
0.4 1.5 GO:0034405 response to fluid shear stress(GO:0034405)
0.4 5.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 0.9 GO:0034036 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.3 1.9 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.3 1.3 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.3 4.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 14.2 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.2 3.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.2 3.8 GO:0051382 kinetochore assembly(GO:0051382)
0.2 6.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 2.4 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 5.7 GO:0051923 sulfation(GO:0051923)
0.2 11.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 2.1 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.2 1.1 GO:0030801 positive regulation of cyclic nucleotide metabolic process(GO:0030801) positive regulation of cyclic nucleotide biosynthetic process(GO:0030804) positive regulation of nucleotide biosynthetic process(GO:0030810) regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) positive regulation of cyclase activity(GO:0031281) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284) positive regulation of lyase activity(GO:0051349) positive regulation of purine nucleotide biosynthetic process(GO:1900373)
0.2 4.0 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.2 5.3 GO:0051014 actin filament severing(GO:0051014)
0.2 2.7 GO:0003313 heart rudiment development(GO:0003313)
0.2 2.0 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.2 0.8 GO:0051972 regulation of telomerase activity(GO:0051972)
0.2 1.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 4.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 8.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 16.6 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 3.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 1.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 2.9 GO:0071545 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.1 3.1 GO:0001843 neural tube closure(GO:0001843)
0.1 14.1 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 1.7 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.1 1.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.7 GO:0000730 DNA recombinase assembly(GO:0000730)
0.1 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.3 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.1 2.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.8 GO:0030719 P granule organization(GO:0030719)
0.1 1.8 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.1 1.4 GO:0036065 fucosylation(GO:0036065)
0.1 2.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 0.6 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 7.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 1.4 GO:0030259 lipid glycosylation(GO:0030259)
0.1 2.2 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.1 0.3 GO:0006844 acyl carnitine transport(GO:0006844)
0.1 2.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 3.2 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 4.0 GO:0043542 endothelial cell migration(GO:0043542)
0.1 15.8 GO:0006914 autophagy(GO:0006914)
0.1 0.4 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 2.6 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1 1.8 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 0.8 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 1.0 GO:0021984 adenohypophysis development(GO:0021984)
0.1 1.1 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.1 3.4 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.4 GO:0051013 microtubule severing(GO:0051013)
0.0 0.5 GO:0016926 protein desumoylation(GO:0016926)
0.0 2.2 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 1.5 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 1.8 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.2 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 6.6 GO:0033674 positive regulation of kinase activity(GO:0033674)
0.0 1.3 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 1.0 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 1.5 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 13.5 GO:0006412 translation(GO:0006412)
0.0 3.2 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 3.8 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0010656 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0 1.2 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.0 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 2.1 GO:0007269 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 0.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 1.8 GO:0006954 inflammatory response(GO:0006954)
0.0 0.2 GO:0018216 peptidyl-arginine methylation(GO:0018216)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 10.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.8 11.5 GO:0000815 ESCRT III complex(GO:0000815)
0.8 6.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 1.5 GO:0070724 BMP receptor complex(GO:0070724)
0.3 0.8 GO:0033391 chromatoid body(GO:0033391)
0.2 14.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 1.9 GO:0061700 GATOR2 complex(GO:0061700)
0.2 0.7 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.2 8.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 1.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.4 GO:0008352 katanin complex(GO:0008352)
0.1 2.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 2.4 GO:0042555 MCM complex(GO:0042555)
0.1 6.3 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 2.7 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.1 1.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 9.4 GO:0005581 collagen trimer(GO:0005581)
0.1 4.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 4.2 GO:0005643 nuclear pore(GO:0005643)
0.1 7.4 GO:0016324 apical plasma membrane(GO:0016324)
0.1 2.5 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 5.3 GO:0030027 lamellipodium(GO:0030027)
0.1 4.1 GO:0055037 recycling endosome(GO:0055037)
0.1 4.0 GO:0030139 endocytic vesicle(GO:0030139)
0.1 0.8 GO:0030130 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 2.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.8 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 3.8 GO:0016459 myosin complex(GO:0016459)
0.0 1.2 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 31.9 GO:0005615 extracellular space(GO:0005615)
0.0 3.3 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 2.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 3.4 GO:0000785 chromatin(GO:0000785)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0008179 adenylate cyclase binding(GO:0008179)
1.5 6.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
1.5 7.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
1.4 7.0 GO:0038131 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
1.1 5.4 GO:0070573 metallodipeptidase activity(GO:0070573)
1.0 5.2 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.9 10.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.9 15.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.9 2.6 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.7 2.1 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.6 5.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.6 3.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.6 2.2 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.5 2.4 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.5 3.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.4 4.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 2.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.4 11.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.4 4.5 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.4 2.8 GO:0035173 histone kinase activity(GO:0035173)
0.4 6.3 GO:0031386 protein tag(GO:0031386)
0.4 3.5 GO:0015250 water channel activity(GO:0015250)
0.4 5.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.4 2.1 GO:0017040 ceramidase activity(GO:0017040)
0.3 2.0 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.3 3.1 GO:0005522 profilin binding(GO:0005522)
0.3 3.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.3 4.0 GO:0045159 myosin II binding(GO:0045159)
0.3 0.9 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.3 1.9 GO:0070728 leucine binding(GO:0070728)
0.2 2.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.2 26.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 4.9 GO:0008252 nucleotidase activity(GO:0008252)
0.2 4.7 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.2 0.8 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.2 13.8 GO:0003823 antigen binding(GO:0003823)
0.2 14.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 1.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 1.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 1.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 2.2 GO:0070403 NAD+ binding(GO:0070403)
0.1 2.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.7 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 2.5 GO:0005080 protein kinase C binding(GO:0005080)
0.1 6.2 GO:0045182 translation regulator activity(GO:0045182)
0.1 0.4 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.1 2.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 2.7 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 1.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.7 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 4.2 GO:0043022 ribosome binding(GO:0043022)
0.1 1.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.2 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.1 0.8 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 2.4 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 0.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.3 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.1 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 1.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 4.6 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.1 1.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 2.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.9 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 8.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.2 GO:0015278 calcium-release channel activity(GO:0015278)
0.0 0.3 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.5 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 4.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 1.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 2.6 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 1.2 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.7 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.5 GO:0004620 phospholipase activity(GO:0004620)
0.0 2.6 GO:0015293 symporter activity(GO:0015293)
0.0 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.0 3.5 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 4.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 9.4 NABA COLLAGENS Genes encoding collagen proteins
0.2 6.6 PID AURORA A PATHWAY Aurora A signaling
0.2 4.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 5.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 2.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 2.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.5 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 1.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 2.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.3 PID ATR PATHWAY ATR signaling pathway
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.2 4.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
1.1 2.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.4 2.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 9.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.3 4.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 9.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 5.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 2.8 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 4.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.2 2.0 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 2.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 2.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 14.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 2.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 5.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 3.5 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1 2.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.4 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 0.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.2 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 2.8 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 1.0 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.9 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter