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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for sox17

Z-value: 0.68

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Transcription factors associated with sox17

Gene Symbol Gene ID Gene Info
ENSDARG00000101717 SRY-box transcription factor 17

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox17dr11_v1_chr7_-_58776400_58776400-0.295.0e-03Click!

Activity profile of sox17 motif

Sorted Z-values of sox17 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_36738069 6.98 ENSDART00000105590
tryptophan 2,3-dioxygenase a
chr5_+_37978501 6.12 ENSDART00000012050
apolipoprotein A-Ia
chr22_-_26175237 5.98 ENSDART00000108737
complement component c3b, tandem duplicate 2
chr22_-_26236188 5.91 ENSDART00000162640
ENSDART00000167169
ENSDART00000138595
complement component c3b, tandem duplicate 1
chr7_+_21841037 4.96 ENSDART00000077503
transmembrane 4 L six family member 5
chr19_+_9305964 4.42 ENSDART00000136241
si:ch73-15n24.1
chr6_-_40058686 3.65 ENSDART00000103240
urocanate hydratase 1
chr16_-_28658341 3.41 ENSDART00000148456
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr9_+_34127005 3.40 ENSDART00000167384
ENSDART00000078065
coagulation factor V
chr18_+_1837668 3.12 ENSDART00000164210

chr21_+_26748141 2.99 ENSDART00000169025
pyruvate carboxylase a
chr2_+_3472832 2.98 ENSDART00000115278
connexin 47.1
chr5_+_29820266 2.93 ENSDART00000146331
ENSDART00000098315
F11 receptor, tandem duplicate 2
chr9_+_21146862 2.91 ENSDART00000136365
hydroxyacid oxidase 2 (long chain)
chr7_-_52096498 2.89 ENSDART00000098688
ENSDART00000098690
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr14_+_36246726 2.76 ENSDART00000105602
ELOVL fatty acid elongase 6
chr18_+_30915348 2.75 ENSDART00000139398
methenyltetrahydrofolate synthetase domain containing
chr21_+_39963851 2.73 ENSDART00000144435
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr21_+_11385031 2.70 ENSDART00000040598
carboxyl ester lipase, tandem duplicate 2
chr25_-_1720736 2.65 ENSDART00000097256
solute carrier family 6 member 13
chr14_-_41285392 2.59 ENSDART00000147389
transmembrane protein 35
chr6_-_35472923 2.50 ENSDART00000185907
regulator of G protein signaling 8
chr8_-_45277370 2.48 ENSDART00000146364
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr4_-_14328997 2.43 ENSDART00000091151
neural EGFL like 2b
chr15_-_33896159 2.25 ENSDART00000159791
myelin associated glycoprotein
chr24_-_38079261 2.23 ENSDART00000105662
C-reactive protein 1
chr9_-_16218097 2.20 ENSDART00000190503
myosin IB
chr1_+_44800298 2.15 ENSDART00000073712
ENSDART00000187054
transmembrane protein 187
chr5_+_1278092 2.14 ENSDART00000147972
ENSDART00000159783
dynamin 1a
chr3_-_39190317 2.14 ENSDART00000013167
retinol saturase (all-trans-retinol 13,14-reductase)
chr13_+_18659325 2.09 ENSDART00000147905
ENSDART00000188249
ENSDART00000134740
selenoprotein U 1a
chr7_-_52096287 2.08 ENSDART00000174068
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr18_+_10926197 2.06 ENSDART00000192387
tetratricopeptide repeat domain 38
chr11_+_35364445 2.06 ENSDART00000125766
CaM kinase-like vesicle-associated b
chr10_+_4235998 2.02 ENSDART00000169328
phospholipid phosphatase related 1
chr8_+_24747865 1.93 ENSDART00000078656
solute carrier family 16, member 4
chr17_-_33289304 1.89 ENSDART00000135118
ENSDART00000040346
EFR3 homolog Ba (S. cerevisiae)
chr10_-_22845485 1.87 ENSDART00000079454
vesicle-associated membrane protein 2
chr1_-_12278056 1.85 ENSDART00000139336
ENSDART00000137463
complexin 2, like
chr7_+_23495986 1.84 ENSDART00000190739
ENSDART00000115299
ENSDART00000101423
ENSDART00000142401
zgc:109889
chr7_-_40122139 1.76 ENSDART00000173982
si:ch73-174h16.5
chr3_-_55525627 1.76 ENSDART00000189234
testis expressed 2
chr16_+_43152727 1.75 ENSDART00000125590
ENSDART00000154493
ADAM metallopeptidase domain 22
chr24_-_33276139 1.75 ENSDART00000128943
nuclear receptor binding protein 2b
chr19_-_15397946 1.73 ENSDART00000143480
human immunodeficiency virus type I enhancer binding protein 3a
chr8_+_6967108 1.70 ENSDART00000004588
acid-sensing (proton-gated) ion channel 1a
chr3_-_40976463 1.65 ENSDART00000128450
ENSDART00000018676
cytochrome P450, family 3, subfamily c, polypeptide 1
chr16_-_25563508 1.64 ENSDART00000189642
ataxin 1b
chr18_-_34549721 1.62 ENSDART00000137101
ENSDART00000021880
signal sequence receptor, gamma
chr16_+_11623956 1.59 ENSDART00000137788
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr14_-_3174570 1.57 ENSDART00000163585
colony stimulating factor 1 receptor, a
chr14_-_46113321 1.54 ENSDART00000169040
ENSDART00000161475
ENSDART00000124925
si:ch211-235e9.8
chr14_-_9350364 1.52 ENSDART00000164451
family with sequence similarity 46, member D
chr21_-_7178348 1.50 ENSDART00000187467
family with sequence similarity 69, member B
chr18_+_30878196 1.50 ENSDART00000099326
ENSDART00000146041
methenyltetrahydrofolate synthetase domain containing
chr16_+_4138331 1.48 ENSDART00000192403
ENSDART00000193036
metal-regulatory transcription factor 1
chr1_-_42779075 1.47 ENSDART00000133917
leucine rich repeat transmembrane neuronal 1
chr14_+_29609245 1.46 ENSDART00000043058
si:dkey-34l15.2
chr3_-_18711288 1.44 ENSDART00000183885
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a
chr7_-_18601206 1.44 ENSDART00000111636
si:ch211-119e14.2
chr1_-_44704261 1.42 ENSDART00000133210
si:dkey-28b4.8
chr13_+_11439486 1.42 ENSDART00000138312
zinc finger and BTB domain containing 18
chr10_-_2522588 1.41 ENSDART00000081926

chr4_-_50301491 1.41 ENSDART00000163146
si:ch211-197e7.3
chr15_+_22267847 1.39 ENSDART00000110665
sperm autoantigenic protein 17
chr24_-_33284945 1.38 ENSDART00000155429
ENSDART00000112845
zgc:195173
chr14_+_22447662 1.37 ENSDART00000161776
sosondowah ankyrin repeat domain family member Ab
chr3_+_18795570 1.37 ENSDART00000042368
fumarylacetoacetate hydrolase domain containing 1
chr6_+_6780873 1.36 ENSDART00000011865
Sec23 homolog B, COPII coat complex component
chr6_-_43092175 1.35 ENSDART00000084389
leucine rich repeat neuronal 1
chr9_+_31534601 1.35 ENSDART00000133094
si:ch211-168k14.2
chr9_+_19421841 1.34 ENSDART00000159090
ENSDART00000084771
phosphodiesterase 9A
chr3_+_18097700 1.33 ENSDART00000021634
info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a
chr15_+_32423801 1.32 ENSDART00000165591
si:dkey-285b23.3
chr14_-_30897177 1.32 ENSDART00000087918
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3b
chr25_+_4760489 1.32 ENSDART00000167399

chr3_-_13068189 1.31 ENSDART00000167180
protein kinase, cAMP-dependent, regulatory, type I, beta
chr1_-_52498146 1.31 ENSDART00000122217
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr17_+_25289431 1.31 ENSDART00000161002
kelch repeat and BTB (POZ) domain containing 11
chr1_+_6817292 1.31 ENSDART00000145822
ENSDART00000092118
erb-b2 receptor tyrosine kinase 4a
chr7_+_26100024 1.29 ENSDART00000173726
si:ch211-196f2.3
chr5_+_67812062 1.29 ENSDART00000158611
zgc:175280
chr12_-_31103906 1.28 ENSDART00000189099
ENSDART00000121527
ENSDART00000185635
ENSDART00000183754
transcription factor 7 like 2
chr17_-_52595932 1.26 ENSDART00000127225
si:ch211-173a9.7
chr14_-_24101897 1.23 ENSDART00000143695
cytoplasmic polyadenylation element binding protein 4a
chr11_+_15931188 1.20 ENSDART00000165768
ENSDART00000081098
dorsal inhibitory axon guidance protein
chr18_+_17534627 1.20 ENSDART00000061007
metallothionein 2
chr5_-_33606729 1.20 ENSDART00000137073
si:dkey-34e4.1
chr9_+_16854121 1.20 ENSDART00000110866
CLN5, intracellular trafficking protein
chr5_-_54790923 1.19 ENSDART00000176835
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr22_+_25274712 1.18 ENSDART00000137341

chr7_-_71384391 1.17 ENSDART00000112841
coiled-coil domain containing 149a
chr22_+_12361317 1.17 ENSDART00000189963
ENSDART00000159614
R3H domain containing 1
chr1_+_53321878 1.16 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr17_-_52594756 1.15 ENSDART00000167288
si:ch211-173a9.7
chr4_-_63980140 1.14 ENSDART00000160818
zinc finger protein 1091
chr22_+_12361489 1.14 ENSDART00000182483
R3H domain containing 1
chr17_-_20218357 1.11 ENSDART00000155990
ENSDART00000155632
ENSDART00000156540
ENSDART00000063523
O-6-methylguanine-DNA methyltransferase
chr4_+_25693463 1.11 ENSDART00000132864
acyl-CoA thioesterase 18
chr2_+_55199721 1.10 ENSDART00000016143
zmp:0000000521
chr14_+_29941445 1.09 ENSDART00000181761
family with sequence similarity 149 member A
chr15_+_1765988 1.08 ENSDART00000159032
cullin 3b
chr6_+_29923593 1.08 ENSDART00000169687
discs, large homolog 1 (Drosophila)
chr3_-_40976288 1.08 ENSDART00000193553
cytochrome P450, family 3, subfamily c, polypeptide 1
chr4_+_9030609 1.07 ENSDART00000154399
aldehyde dehydrogenase 1 family, member L2
chr18_-_15771551 1.07 ENSDART00000130931
ENSDART00000154079
si:ch211-219a15.3
chr21_+_18353703 1.06 ENSDART00000181396
ENSDART00000166359
si:ch73-287m6.1
chr21_-_2248239 1.06 ENSDART00000169448
si:ch73-299h12.1
chr23_+_25201077 1.06 ENSDART00000136675
si:dkey-151g10.3
chr23_-_45319592 1.06 ENSDART00000189861
coiled-coil domain containing 171
chr17_+_24756379 1.05 ENSDART00000185059
SH3 and cysteine rich domain
chr19_+_42955280 1.04 ENSDART00000141225
fatty acid binding protein 3, muscle and heart
chr14_+_3411771 1.04 ENSDART00000164778
transient receptor potential cation channel, subfamily C, member 3
chr11_-_29833698 1.02 ENSDART00000079149
X-linked Kx blood group (McLeod syndrome)
chr11_+_30636351 1.02 ENSDART00000087909
transmembrane protein 246
chr3_+_15279016 1.01 ENSDART00000182005
aspartate beta-hydroxylase domain containing 1
chr14_+_25464681 1.01 ENSDART00000067500
ENSDART00000187601
si:dkey-280e21.3
chr9_-_30346279 1.01 ENSDART00000089488
synaptotagmin-like 5
chr12_-_41662327 0.99 ENSDART00000191602
ENSDART00000170423
Janus kinase and microtubule interacting protein 3
chr18_-_16181952 0.99 ENSDART00000157824
solute carrier family 6 (neutral amino acid transporter), member 15
chr20_+_25911342 0.99 ENSDART00000146004
tau tubulin kinase 2b
chr11_-_27537593 0.98 ENSDART00000173444
ENSDART00000172895
ENSDART00000088177
protein tyrosine phosphatase domain containing 1a
chr15_-_33904831 0.98 ENSDART00000164333
ENSDART00000165404
myelin associated glycoprotein
chr17_-_19963718 0.98 ENSDART00000154251
cholinergic receptor, muscarinic 3a
chr19_-_36234185 0.97 ENSDART00000186003
CUB and Sushi multiple domains 2
chr20_+_21583639 0.97 ENSDART00000131069
estrogen receptor 2a
chr16_-_25400257 0.97 ENSDART00000040756
zgc:136493
chr21_+_33503835 0.96 ENSDART00000125658
clathrin interactor 1b
chr2_-_51630555 0.96 ENSDART00000171746
polymeric immunoglobulin receptor
chr22_+_1779401 0.95 ENSDART00000170126
zinc finger protein 1154
chr16_+_50741154 0.94 ENSDART00000101627
zgc:110372
chr2_-_42843797 0.94 ENSDART00000137913
adenylate cyclase 8 (brain)
chr20_-_35040041 0.94 ENSDART00000131919
kinesin family member 26Bb
chr2_-_10062575 0.93 ENSDART00000091726
family with sequence similarity 78, member B a
chr1_-_49649122 0.93 ENSDART00000134399
STE20-like kinase b
chr16_+_5184402 0.91 ENSDART00000156685
SOGA family member 3a
chr14_+_6954579 0.91 ENSDART00000060998
NME/NM23 family member 5
chr7_+_33145529 0.90 ENSDART00000052387
intelectin 2
chr11_-_41996957 0.89 ENSDART00000055706
hairy and enhancer of split-related 15, tandem duplicate 2
chr7_-_39378903 0.88 ENSDART00000173659
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr20_+_40457599 0.87 ENSDART00000017553
serine incorporator 1
chr4_-_75803810 0.87 ENSDART00000163517
si:ch211-203c5.3
chr6_-_7842078 0.87 ENSDART00000065507
phospholipid phosphatase related 2b
chr14_+_17382803 0.86 ENSDART00000040383
si:ch211-255i20.3
chr24_-_25673405 0.86 ENSDART00000186081
ENSDART00000110241
ENSDART00000142351
connector enhancer of kinase suppressor of Ras 2a
chr21_-_37972412 0.85 ENSDART00000186315
ripply transcriptional repressor 1
chr2_-_12502495 0.85 ENSDART00000186781
dipeptidyl-peptidase 6b
chr11_+_6152643 0.84 ENSDART00000012789
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr14_+_25817628 0.83 ENSDART00000047680
glycine receptor, alpha 1
chr2_+_24867534 0.83 ENSDART00000158050
RAB3A, member RAS oncogene family, a
chr17_-_13070602 0.82 ENSDART00000188311
ENSDART00000193428

chr21_+_21791343 0.81 ENSDART00000151654
sialidase 3 (membrane sialidase), tandem duplicate 1
chr8_+_13368150 0.80 ENSDART00000114699
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr11_-_1948784 0.80 ENSDART00000082475
nuclear receptor subfamily 1, group D, member 4b
chr5_+_45990046 0.80 ENSDART00000084024
synaptic vesicle glycoprotein 2C
chr12_+_2870671 0.80 ENSDART00000165225
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b
chr20_-_36227500 0.79 ENSDART00000166054

chr13_+_41917606 0.79 ENSDART00000114741
polymerase (RNA) I polypeptide B
chr13_+_40034176 0.76 ENSDART00000189797
golgin A7 family, member Bb
chr10_-_3258073 0.75 ENSDART00000113162
phosphatidylinositol 4-kinase, catalytic, alpha a
chr4_+_47445318 0.75 ENSDART00000183819
si:dkey-124l13.1
chr1_-_39977551 0.74 ENSDART00000139354
storkhead box 2a
chr17_-_6519423 0.74 ENSDART00000175626

chr7_-_35036770 0.74 ENSDART00000123174
galanin receptor 1b
chr17_-_6399920 0.73 ENSDART00000022010
human immunodeficiency virus type I enhancer binding protein 2b
chr1_+_29281764 0.73 ENSDART00000112106
family with sequence similarity 155, member A
chr6_+_6828167 0.72 ENSDART00000181284
si:ch211-85n16.4
chr18_+_38807239 0.71 ENSDART00000184332
family with sequence similarity 214, member A
chr8_-_43120844 0.71 ENSDART00000193242
coiled-coil domain containing 92
chr25_+_22682065 0.70 ENSDART00000129484
Usher syndrome 1C
chr23_-_15036789 0.69 ENSDART00000056570
PHD finger protein 20, b
chr6_-_39198912 0.69 ENSDART00000077938
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1b
chr13_-_40316367 0.69 ENSDART00000009343
pyridine nucleotide-disulphide oxidoreductase domain 2
chr7_-_34329527 0.69 ENSDART00000173454
MAP-kinase activating death domain
chr17_+_18031899 0.68 ENSDART00000022758
SET domain containing 3
chr16_+_25074029 0.68 ENSDART00000155465
si:dkeyp-84f3.9
chr20_+_18945057 0.67 ENSDART00000035447
myotubularin related protein 9
chr7_+_65876335 0.67 ENSDART00000150143
TEA domain family member 1b
chr13_-_31687925 0.67 ENSDART00000085989
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
chr21_-_1742159 0.66 ENSDART00000151049
one cut homeobox 2
chr1_-_57172294 0.66 ENSDART00000063774
Rac family small GTPase 1, like
chr3_-_25119839 0.65 ENSDART00000154724
chondroadherin-like a
chr10_+_33627429 0.65 ENSDART00000138542
beta 3-glucosyltransferase b
chr2_-_9260002 0.65 ENSDART00000057299
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5a
chr5_-_41860556 0.65 ENSDART00000140154
si:dkey-65b12.12
chr17_-_20218167 0.64 ENSDART00000154479
O-6-methylguanine-DNA methyltransferase
chr6_+_54498220 0.64 ENSDART00000103282
si:ch211-233f11.5
chr16_-_52736549 0.64 ENSDART00000146607
antizyme inhibitor 1a
chr4_+_13412030 0.64 ENSDART00000003694
cullin-associated and neddylation-dissociated 1
chr23_-_36670369 0.63 ENSDART00000006881
zinc finger and BTB domain containing 39
chr12_+_29240124 0.63 ENSDART00000053761
ENSDART00000130172
BMS1 ribosome biogenesis factor
chr9_+_48085039 0.63 ENSDART00000186734
si:ch73-54b5.2
chr21_-_12036134 0.63 ENSDART00000031658
tubulin polyglutamylase complex subunit 2
chr14_+_11909966 0.62 ENSDART00000171829
FERM and PDZ domain containing 3
chr21_-_37973081 0.61 ENSDART00000136569
ripply transcriptional repressor 1
chr23_-_44470253 0.61 ENSDART00000176333
si:ch1073-228j22.2
chr7_-_24204200 0.60 ENSDART00000087298
guanosine monophosphate reductase 2
chr23_-_10048533 0.60 ENSDART00000166663
plexin b1a
chr4_-_71904377 0.60 ENSDART00000191852
si:dkeyp-4f2.1
chr15_-_30815826 0.60 ENSDART00000156160
ENSDART00000145918
musashi RNA-binding protein 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of sox17

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.1 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
1.2 3.7 GO:0043606 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.9 7.0 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.6 2.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.4 1.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.4 2.6 GO:0043091 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.4 3.2 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.4 1.6 GO:0071674 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) regulation of odontogenesis(GO:0042481) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.4 1.5 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.4 1.1 GO:0009258 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.3 1.0 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.3 1.3 GO:0010226 response to lithium ion(GO:0010226)
0.3 0.9 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.3 0.8 GO:0071361 cellular response to ethanol(GO:0071361)
0.3 0.8 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 1.0 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.2 2.7 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.2 1.7 GO:0070207 protein homotrimerization(GO:0070207)
0.2 0.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.6 GO:0010265 SCF complex assembly(GO:0010265)
0.2 2.9 GO:0050892 intestinal absorption(GO:0050892)
0.2 1.0 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.2 0.8 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.2 1.2 GO:0002931 response to ischemia(GO:0002931)
0.2 1.4 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 2.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 2.8 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.9 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.4 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) distal tubule morphogenesis(GO:0072156) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.1 1.8 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.6 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 1.2 GO:0010043 response to zinc ion(GO:0010043)
0.1 3.4 GO:0009636 response to toxic substance(GO:0009636)
0.1 0.4 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 1.0 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 1.6 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 1.2 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 1.5 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 4.7 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 1.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.5 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 0.7 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.4 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 0.2 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 0.4 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 1.4 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.1 1.4 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.7 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.2 GO:0015074 DNA integration(GO:0015074)
0.1 0.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.8 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.9 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 1.1 GO:1903286 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.9 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.1 0.2 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.7 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.1 0.8 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.1 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 1.6 GO:0099633 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.1 4.7 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.1 1.1 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.2 GO:0070084 protein initiator methionine removal(GO:0070084)
0.1 0.1 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 1.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:1902592 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.0 1.2 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.7 GO:0001964 startle response(GO:0001964)
0.0 0.9 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.4 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.3 GO:0035475 angioblast cell migration involved in selective angioblast sprouting(GO:0035475)
0.0 1.9 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.4 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.0 0.6 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 0.9 GO:0006828 manganese ion transport(GO:0006828)
0.0 1.2 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.7 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 2.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.4 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 2.1 GO:0007599 hemostasis(GO:0007599)
0.0 0.3 GO:0006868 glutamine transport(GO:0006868)
0.0 0.6 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.6 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.1 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 1.9 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.6 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.7 GO:0035329 hippo signaling(GO:0035329)
0.0 0.8 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.8 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0009651 response to salt stress(GO:0009651)
0.0 0.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.6 GO:0010906 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 1.1 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.6 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 1.1 GO:0009755 hormone-mediated signaling pathway(GO:0009755)
0.0 1.6 GO:1990778 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 2.3 GO:0006869 lipid transport(GO:0006869)
0.0 0.7 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.0 GO:0003341 cilium movement(GO:0003341)
0.0 1.0 GO:0098661 inorganic anion transmembrane transport(GO:0098661)
0.0 1.0 GO:0016573 histone acetylation(GO:0016573)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.1 GO:0042627 chylomicron(GO:0042627)
0.3 1.3 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.2 2.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.6 GO:1902560 GMP reductase complex(GO:1902560)
0.1 2.5 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.5 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 2.2 GO:0005903 brush border(GO:0005903)
0.1 0.4 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.1 1.8 GO:0031209 SCAR complex(GO:0031209)
0.1 0.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.7 GO:0071546 pi-body(GO:0071546)
0.1 1.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.7 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.1 1.4 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 1.9 GO:0043195 terminal bouton(GO:0043195)
0.1 0.6 GO:0071914 prominosome(GO:0071914)
0.1 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 1.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.7 GO:0044545 NSL complex(GO:0044545)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.6 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 3.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0070187 telosome(GO:0070187)
0.0 1.0 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.8 GO:0043204 perikaryon(GO:0043204)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.8 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.6 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.4 GO:0031514 motile cilium(GO:0031514)
0.0 0.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.5 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 1.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 2.3 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.5 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
1.2 6.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.1 3.4 GO:0015562 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
1.0 3.0 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.9 2.7 GO:0004771 sterol esterase activity(GO:0004771)
0.4 2.6 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.4 1.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.3 1.7 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.3 1.0 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 2.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.3 0.8 GO:0070336 flap-structured DNA binding(GO:0070336)
0.3 1.4 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 0.6 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.2 1.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 1.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 1.4 GO:0004630 phospholipase D activity(GO:0004630)
0.2 3.2 GO:0033691 sialic acid binding(GO:0033691)
0.2 1.8 GO:0008172 S-methyltransferase activity(GO:0008172)
0.2 2.7 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.2 0.6 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 1.0 GO:1903924 estradiol binding(GO:1903924)
0.1 1.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 2.4 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.7 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 2.9 GO:0010181 FMN binding(GO:0010181)
0.1 2.8 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.7 GO:0004966 galanin receptor activity(GO:0004966)
0.1 3.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.3 GO:0004046 aminoacylase activity(GO:0004046)
0.1 7.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 1.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.8 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.6 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 1.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 3.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.8 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.7 GO:0034584 piRNA binding(GO:0034584)
0.1 1.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.2 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 1.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.8 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 1.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.4 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.1 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 3.4 GO:0005507 copper ion binding(GO:0005507)
0.0 3.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 1.1 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 2.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.3 GO:0035173 histone kinase activity(GO:0035173)
0.0 6.9 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.9 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.6 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.4 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 2.1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.8 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 2.4 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.7 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.8 GO:0015370 solute:sodium symporter activity(GO:0015370)
0.0 0.4 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.0 GO:0044325 ion channel binding(GO:0044325)
0.0 1.0 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 1.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.9 GO:0019902 phosphatase binding(GO:0019902)
0.0 1.3 GO:0030276 clathrin binding(GO:0030276)
0.0 1.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.2 GO:0015293 symporter activity(GO:0015293)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.2 PID IL5 PATHWAY IL5-mediated signaling events
0.1 0.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 4.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID RAC1 PATHWAY RAC1 signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3 2.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 3.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 1.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 0.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 2.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 2.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 2.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.6 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 1.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 0.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.8 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 2.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 2.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.4 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein