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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for sox19b+sox3

Z-value: 1.02

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Transcription factors associated with sox19b+sox3

Gene Symbol Gene ID Gene Info
sox19b
ENSDARG00000040266 SRY-box transcription factor 19b
sox3
ENSDARG00000053569 SRY-box transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox3dr11_v1_chr14_-_32744464_327444640.321.5e-03Click!
sox19bdr11_v1_chr7_-_26497947_264979470.286.5e-03Click!

Activity profile of sox19b+sox3 motif

Sorted Z-values of sox19b+sox3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_21801277 11.74 ENSDART00000088407
trim108
tripartite motif containing 108
chr5_-_30615901 8.06 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr13_+_22675802 8.05 ENSDART00000145538
ENSDART00000143312
zgc:193505
zgc:193505
chr10_+_33171501 7.49 ENSDART00000159666
myl10
myosin, light chain 10, regulatory
chr14_+_38786298 7.15 ENSDART00000164440
si:ch211-195b11.3
si:ch211-195b11.3
chr23_-_10175898 7.01 ENSDART00000146185
krt5
keratin 5
chr21_+_25688388 6.68 ENSDART00000125709
bicdl2
bicaudal-D-related protein 2
chr7_+_35268880 6.65 ENSDART00000182231
dpep2
dipeptidase 2
chr14_-_8080416 6.59 ENSDART00000045109
zgc:92242
zgc:92242
chr5_-_55560937 6.45 ENSDART00000148436
gna14
guanine nucleotide binding protein (G protein), alpha 14
chr5_+_23256187 6.01 ENSDART00000168717
ENSDART00000142915
si:dkey-125i10.3
si:dkey-125i10.3
chr3_-_57425961 5.90 ENSDART00000033716
socs3a
suppressor of cytokine signaling 3a
chr25_+_35502552 5.82 ENSDART00000189612
ENSDART00000058443
fibina
fin bud initiation factor a
chr3_+_12755535 5.81 ENSDART00000161286
cyp2k17
cytochrome P450, family 2, subfamily K, polypeptide17
chr16_+_23960744 5.74 ENSDART00000058965
apoeb
apolipoprotein Eb
chr19_+_10937932 5.73 ENSDART00000168968
si:ch73-347e22.8
si:ch73-347e22.8
chr3_-_50139860 5.73 ENSDART00000101563
btr02
bloodthirsty-related gene family, member 2
chr14_+_11457500 5.71 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr12_+_48340133 5.57 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
ddit4
DNA-damage-inducible transcript 4
chr23_+_42813415 5.55 ENSDART00000055577
myl9a
myosin, light chain 9a, regulatory
chr7_-_7398350 5.55 ENSDART00000012637
zgc:101810
zgc:101810
chr4_-_16354292 5.54 ENSDART00000139919
lum
lumican
chr16_+_23960933 5.53 ENSDART00000146077
apoeb
apolipoprotein Eb
chr24_+_26006730 5.41 ENSDART00000140384
ENSDART00000139184
ccl20b
chemokine (C-C motif) ligand 20b
chr5_-_46505691 5.33 ENSDART00000111589
ENSDART00000122966
ENSDART00000166907
hapln1a
hyaluronan and proteoglycan link protein 1a
chr3_-_31258459 5.26 ENSDART00000177928
LO017965.1

chr3_+_3545825 5.12 ENSDART00000109060
CR589947.1

chr8_-_31107537 5.11 ENSDART00000098925
vgll4l
vestigial like 4 like
chr17_-_8862424 4.99 ENSDART00000064633
nkl.4
NK-lysin tandem duplicate 4
chr18_-_15467446 4.89 ENSDART00000187847
endouc
endonuclease, polyU-specific C
chr12_-_30523216 4.85 ENSDART00000152896
ENSDART00000153191
plekhs1
pleckstrin homology domain containing, family S member 1
chr4_+_18843015 4.84 ENSDART00000152086
ENSDART00000066977
ENSDART00000132567
bik
BCL2 interacting killer
chr7_+_48761875 4.79 ENSDART00000003690
acana
aggrecan a
chr16_-_9675982 4.79 ENSDART00000113724
mal2
mal, T cell differentiation protein 2 (gene/pseudogene)
chr24_-_11076400 4.77 ENSDART00000003195
chmp4c
charged multivesicular body protein 4C
chr12_-_30558694 4.76 ENSDART00000153417
si:ch211-28p3.3
si:ch211-28p3.3
chr11_+_10548171 4.66 ENSDART00000191497
b3gnt5a
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr16_+_29586468 4.61 ENSDART00000148926
mcl1b
MCL1, BCL2 family apoptosis regulator b
chr7_+_22688781 4.60 ENSDART00000173509
ugt5g1
UDP glucuronosyltransferase 5 family, polypeptide G1
chr15_+_37331585 4.58 ENSDART00000170715
zgc:171592
zgc:171592
chr7_-_53117131 4.56 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cdh1
cadherin 1, type 1, E-cadherin (epithelial)
chr24_+_25069609 4.53 ENSDART00000115165
amer2
APC membrane recruitment protein 2
chr12_-_30540699 4.49 ENSDART00000167712
ENSDART00000102464
zgc:153920
zgc:153920
chr22_-_10121880 4.44 ENSDART00000002348
rdh5
retinol dehydrogenase 5 (11-cis/9-cis)
chr22_+_19220459 4.38 ENSDART00000163070
si:dkey-21e2.7
si:dkey-21e2.7
chr25_-_22187397 4.32 ENSDART00000123211
ENSDART00000139110
pkp3a
plakophilin 3a
chr5_+_15203421 4.29 ENSDART00000040826
tbx1
T-box 1
chr16_-_31976269 4.28 ENSDART00000139664
styk1
serine/threonine/tyrosine kinase 1
chr23_+_20110086 4.27 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr7_+_20019125 4.26 ENSDART00000186391
bcl6b
B-cell CLL/lymphoma 6, member B
chr1_+_31054915 4.18 ENSDART00000148968
itga6b
integrin, alpha 6b
chr19_+_24488403 4.12 ENSDART00000052421
txnipa
thioredoxin interacting protein a
chr5_+_54938634 4.09 ENSDART00000163050
ENSDART00000145765
cd180
CD180 molecule
chr5_-_30984010 4.08 ENSDART00000182367
spns3
spinster homolog 3 (Drosophila)
chr21_+_33459524 4.05 ENSDART00000053205
cd74b
CD74 molecule, major histocompatibility complex, class II invariant chain b
chr19_-_10771558 4.03 ENSDART00000085165
slc9a3.2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3, tandem duplicate 2
chr5_-_37117778 4.03 ENSDART00000149138
il13ra2
interleukin 13 receptor, alpha 2
chr7_+_48761646 4.02 ENSDART00000017467
acana
aggrecan a
chr1_+_22654875 3.93 ENSDART00000019698
ENSDART00000161874
anxa5b
annexin A5b
chr1_-_18615063 3.91 ENSDART00000014916
klf3
Kruppel-like factor 3 (basic)
chr22_+_22010128 3.90 ENSDART00000172610
gna15.2
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 2
chr24_+_20373605 3.75 ENSDART00000112349
plcd1a
phospholipase C, delta 1a
chr22_-_10541372 3.74 ENSDART00000179708
si:dkey-42i9.4
si:dkey-42i9.4
chr14_-_34059681 3.71 ENSDART00000003993
itk
IL2 inducible T cell kinase
chr4_+_4232562 3.70 ENSDART00000177529
smkr1
small lysine rich protein 1
chr6_-_1223551 3.70 ENSDART00000182112
CABZ01063034.1

chr6_+_12968101 3.60 ENSDART00000013781
mcm6
minichromosome maintenance complex component 6
chr22_-_3914162 3.60 ENSDART00000187174
ENSDART00000190612
ENSDART00000187928
ENSDART00000057224
ENSDART00000184758
mhc1uma
major histocompatibility complex class I UMA
chr19_+_19762183 3.60 ENSDART00000163611
ENSDART00000187604
hoxa3a
homeobox A3a
chr22_+_30631072 3.59 ENSDART00000059970
zmp:0000000606
zmp:0000000606
chr6_+_30668098 3.55 ENSDART00000112294
ttc22
tetratricopeptide repeat domain 22
chr5_+_1589458 3.49 ENSDART00000167473
CABZ01076669.1

chr9_+_23770666 3.45 ENSDART00000182493
si:ch211-219a4.3
si:ch211-219a4.3
chr6_-_52675630 3.40 ENSDART00000083830
sdc4
syndecan 4
chr8_+_34731982 3.39 ENSDART00000066050
hpdb
4-hydroxyphenylpyruvate dioxygenase b
chr25_+_14109626 3.39 ENSDART00000109883
actc1c
actin, alpha, cardiac muscle 1c
chr7_+_38380135 3.30 ENSDART00000174005
rhpn2
rhophilin, Rho GTPase binding protein 2
chr9_-_6380653 3.26 ENSDART00000078523
ecrg4a
esophageal cancer related gene 4a
chr20_+_6533260 3.25 ENSDART00000135005
ENSDART00000166356
si:ch211-191a24.4
si:ch211-191a24.4
chr22_+_661711 3.22 ENSDART00000113795
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr5_-_41841892 3.21 ENSDART00000167089
si:dkey-65b12.6
si:dkey-65b12.6
chr23_+_42819221 3.20 ENSDART00000180495
myl9a
myosin, light chain 9a, regulatory
chr10_-_25628555 3.20 ENSDART00000143978
tiam1a
T cell lymphoma invasion and metastasis 1a
chr13_-_13294847 3.19 ENSDART00000125883
ENSDART00000013534
fgfr3
fibroblast growth factor receptor 3
chr3_+_32125452 3.16 ENSDART00000110396
zgc:194125
zgc:194125
chr23_-_14830627 3.12 ENSDART00000134659
sla2
Src-like-adaptor 2
chr7_+_39410180 3.09 ENSDART00000168641
CT030188.1

chr8_-_13013123 3.08 ENSDART00000147802
dennd2da
DENN/MADD domain containing 2Da
chr17_-_5860222 3.06 ENSDART00000058894
si:ch73-340m8.2
si:ch73-340m8.2
chr22_+_18886209 3.05 ENSDART00000144402
fstl3
follistatin-like 3 (secreted glycoprotein)
chr8_-_39903803 3.05 ENSDART00000012391
cabp1a
calcium binding protein 1a
chr9_-_14084743 3.04 ENSDART00000056105
fer1l6
fer-1-like family member 6
chr10_+_8690936 3.03 ENSDART00000144218
si:dkey-27b3.4
si:dkey-27b3.4
chr14_+_10461264 3.02 ENSDART00000081095
cysltr1
cysteinyl leukotriene receptor 1
chr8_-_36327328 3.01 ENSDART00000183333
zgc:103700
zgc:103700
chr18_-_37241080 2.99 ENSDART00000126421
ENSDART00000078064
six9
SIX homeobox 9
chr16_+_50089417 2.99 ENSDART00000153675
nr1d2a
nuclear receptor subfamily 1, group D, member 2a
chr22_+_3914318 2.98 ENSDART00000188774
ENSDART00000082034
FO904903.1
Danio rerio major histocompatibility complex class I ULA (mhc1ula), mRNA.
chr3_+_3573696 2.97 ENSDART00000169680
CR589947.2

chr17_+_4408809 2.93 ENSDART00000113401
si:zfos-364h11.1
si:zfos-364h11.1
chr22_+_19264181 2.92 ENSDART00000192750
ENSDART00000137591
ENSDART00000136197
si:dkey-78l4.5
si:dkey-21e2.11
si:dkey-78l4.5
si:dkey-21e2.11
chr8_+_44358443 2.91 ENSDART00000189130
ENSDART00000189212
CU914776.2

chr6_+_2030703 2.89 ENSDART00000109679
ENSDART00000187502
ENSDART00000191165
ENSDART00000187544
quo
quattro
chr9_-_42696408 2.89 ENSDART00000144744
col5a2a
collagen, type V, alpha 2a
chr3_-_32170850 2.87 ENSDART00000055307
ENSDART00000157366
tnnt1
troponin T type 1 (skeletal, slow)
chr16_+_21790870 2.84 ENSDART00000155039
trim108
tripartite motif containing 108
chr7_+_29293452 2.83 ENSDART00000127358
si:ch211-112g6.4
si:ch211-112g6.4
chr14_+_21222287 2.83 ENSDART00000159905
si:ch211-175m2.4
si:ch211-175m2.4
chr15_-_36533322 2.83 ENSDART00000156466
ENSDART00000121755
si:dkey-262k9.4
si:dkey-262k9.4
chr1_-_40735381 2.81 ENSDART00000093269
zgc:153642
zgc:153642
chr20_+_38257766 2.75 ENSDART00000147485
ENSDART00000149160
ccl38.6
chemokine (C-C motif) ligand 38, duplicate 6
chr23_-_28141419 2.74 ENSDART00000133039
tac3a
tachykinin 3a
chr1_+_44906517 2.73 ENSDART00000142820
wu:fc21g02
wu:fc21g02
chr23_-_5683147 2.70 ENSDART00000102766
ENSDART00000067351
tnnt2a
troponin T type 2a (cardiac)
chr19_+_12915498 2.70 ENSDART00000132892
cthrc1a
collagen triple helix repeat containing 1a
chr12_-_44010532 2.64 ENSDART00000183875
si:ch211-182p11.1
si:ch211-182p11.1
chr3_+_57820913 2.62 ENSDART00000168101
CU571328.1

chr24_-_19719240 2.61 ENSDART00000135405
csrnp1b
cysteine-serine-rich nuclear protein 1b
chr7_+_2245815 2.60 ENSDART00000114434
si:ch211-285c6.4
si:ch211-285c6.4
chr12_-_36268723 2.60 ENSDART00000113740
kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr1_-_26027327 2.58 ENSDART00000171292
ENSDART00000170878
si:ch211-145b13.6
si:ch211-145b13.6
chr8_-_46509194 2.57 ENSDART00000038924
sult1st1
sulfotransferase family 1, cytosolic sulfotransferase 1
chr1_+_218524 2.56 ENSDART00000109529
tmco3
transmembrane and coiled-coil domains 3
chr22_+_15898221 2.56 ENSDART00000062587
klf2a
Kruppel-like factor 2a
chr7_-_51368681 2.55 ENSDART00000146385
arhgap36
Rho GTPase activating protein 36
chr21_+_11776328 2.55 ENSDART00000134469
ENSDART00000081646
glrx
glutaredoxin (thioltransferase)
chr21_+_27189490 2.55 ENSDART00000125349
bada
BCL2 associated agonist of cell death a
chr18_-_7481036 2.52 ENSDART00000101292
si:dkey-238c7.16
si:dkey-238c7.16
chr7_+_39410393 2.51 ENSDART00000158561
ENSDART00000185173
CT030188.1

chr23_+_35918530 2.49 ENSDART00000049551
rarga
retinoic acid receptor gamma a
chr9_-_24244383 2.48 ENSDART00000182407
cavin2a
caveolae associated protein 2a
chr12_-_30777540 2.45 ENSDART00000126466
entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr15_+_12429206 2.45 ENSDART00000168997
tmprss4a
transmembrane protease, serine 4a
chr18_-_6634424 2.44 ENSDART00000062423
ENSDART00000179955
tnni1c
troponin I, skeletal, slow c
chr15_+_22448456 2.44 ENSDART00000040542
ENSDART00000190270
ENSDART00000185897
arhgef12a
Rho guanine nucleotide exchange factor (GEF) 12a
chr5_+_27898226 2.44 ENSDART00000098604
ENSDART00000180251
adam28
ADAM metallopeptidase domain 28
chr2_+_2967255 2.43 ENSDART00000167649
ENSDART00000166449
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr17_+_45405821 2.42 ENSDART00000189482
ENSDART00000177422
tagapa
T cell activation RhoGTPase activating protein a
chr1_+_36651059 2.42 ENSDART00000187475
ednraa
endothelin receptor type Aa
chr6_+_54576520 2.42 ENSDART00000093199
ENSDART00000127519
ENSDART00000157142
tead3b
TEA domain family member 3 b
chr3_-_32956808 2.42 ENSDART00000183902
casp6l1
caspase 6, apoptosis-related cysteine peptidase, like 1
chr18_-_6633984 2.41 ENSDART00000185241
tnni1c
troponin I, skeletal, slow c
chr12_-_30777743 2.39 ENSDART00000148888
entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr20_+_34770197 2.39 ENSDART00000018304
mcm3
minichromosome maintenance complex component 3
chr6_-_6993046 2.38 ENSDART00000053304
si:ch211-114n24.6
si:ch211-114n24.6
chr5_+_4564233 2.38 ENSDART00000193435
CABZ01058647.1

chr21_-_26495700 2.38 ENSDART00000109379
cd248b
CD248 molecule, endosialin b
chr6_-_40098641 2.37 ENSDART00000017402
ip6k2b
inositol hexakisphosphate kinase 2b
chr19_+_10603405 2.36 ENSDART00000151135
si:dkey-211g8.8
si:dkey-211g8.8
chr3_+_33761549 2.36 ENSDART00000169337
ier2a
immediate early response 2a
chr2_-_23390779 2.36 ENSDART00000020136
ivns1abpb
influenza virus NS1A binding protein b
chr5_+_38680247 2.34 ENSDART00000132763
si:dkey-58f10.11
si:dkey-58f10.11
chr9_-_30220818 2.34 ENSDART00000140929
si:dkey-100n23.3
si:dkey-100n23.3
chr25_-_14433503 2.32 ENSDART00000103957
exoc3l1
exocyst complex component 3-like 1
chr22_-_15693085 2.31 ENSDART00000141861
si:ch1073-396h14.1
si:ch1073-396h14.1
chr9_-_7683799 2.26 ENSDART00000102713
si:ch73-199e17.1
si:ch73-199e17.1
chr7_-_28681724 2.21 ENSDART00000162400
adgrg1
adhesion G protein-coupled receptor G1
chr10_+_44042033 2.21 ENSDART00000190006
ENSDART00000046172
cryba4
crystallin, beta A4
chr11_-_11890001 2.19 ENSDART00000081544
wipf2a
WAS/WASL interacting protein family, member 2a
chr23_+_45025909 2.19 ENSDART00000188105
hmgb2b
high mobility group box 2b
chr5_-_36949476 2.18 ENSDART00000047269
h3f3c
H3 histone, family 3C
chr16_-_21799407 2.18 ENSDART00000123717
FP015862.4

chr15_+_22014029 2.17 ENSDART00000079504
ankk1
ankyrin repeat and kinase domain containing 1
chr23_+_24085531 2.17 ENSDART00000139710
ttll10
tubulin tyrosine ligase-like family, member 10
chr4_-_4261673 2.16 ENSDART00000150694
cd9b
CD9 molecule b
chr16_+_30316177 2.15 ENSDART00000109505
tmem79b
transmembrane protein 79b
chr10_+_24690534 2.14 ENSDART00000079549
tpte
transmembrane phosphatase with tensin homology
chr19_+_20778011 2.14 ENSDART00000024208
nutf2l
nuclear transport factor 2, like
chr2_-_27900518 2.13 ENSDART00000109561
ENSDART00000077720
zgc:163121
zgc:163121
chr12_-_28848015 2.12 ENSDART00000153200
si:ch211-194k22.8
si:ch211-194k22.8
chr11_+_8129536 2.12 ENSDART00000158112
ENSDART00000011183
prkacba
protein kinase, cAMP-dependent, catalytic, beta a
chr3_-_16110351 2.12 ENSDART00000064838
lasp1
LIM and SH3 protein 1
chr16_-_32208728 2.12 ENSDART00000023995
calhm5.2
calcium homeostasis modulator family member 5, tandem duplicate 2
chr23_+_26079467 2.11 ENSDART00000129617
atp6ap1b
ATPase H+ transporting accessory protein 1b
chr18_+_40525408 2.09 ENSDART00000132833
vwa7
von Willebrand factor A domain containing 7
chr21_+_22738939 2.08 ENSDART00000151342
ENSDART00000079145
arhgap42a
Rho GTPase activating protein 42a
chr10_+_29840725 2.08 ENSDART00000127268
BX120005.1

chr11_+_27274355 2.08 ENSDART00000113707
fbln2
fibulin 2
chr18_-_12327426 2.07 ENSDART00000136992
ENSDART00000114024
fam107b
family with sequence similarity 107, member B
chr18_+_48428713 2.06 ENSDART00000076861
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr19_+_47394270 2.06 ENSDART00000171281
psmb2
proteasome subunit beta 2
chr23_+_42336084 2.04 ENSDART00000158959
ENSDART00000161812
cyp2aa7
cyp2aa8
cytochrome P450, family 2, subfamily AA, polypeptide 7
cytochrome P450, family 2, subfamily AA, polypeptide 8
chr22_-_15577060 2.03 ENSDART00000176291
hsh2d
hematopoietic SH2 domain containing
chr1_-_49498116 2.02 ENSDART00000137357
zgc:175214
zgc:175214
chr12_-_16990896 2.02 ENSDART00000152402
ifit12
interferon-induced protein with tetratricopeptide repeats 12
chr18_+_44649804 2.02 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr16_-_31598771 2.02 ENSDART00000016386
tg
thyroglobulin
chr1_-_8651718 2.01 ENSDART00000133319
actb1
actin, beta 1
chr6_+_45932276 2.00 ENSDART00000103491
rbp7b
retinol binding protein 7b, cellular
chr23_+_25428513 2.00 ENSDART00000144554
fmnl3
formin-like 3
chr19_+_4038589 2.00 ENSDART00000169271
btr23
bloodthirsty-related gene family, member 23
chr4_-_63848305 1.99 ENSDART00000097308
BX901974.1

chr15_-_20400423 1.99 ENSDART00000081290
ENSDART00000156813
ENSDART00000192427
rnaset2l
ribonuclease T2, like
chr5_-_51756210 1.98 ENSDART00000163464
lhfpl2b
LHFPL tetraspan subfamily member 2b
chr5_-_24127310 1.98 ENSDART00000182700
ENSDART00000154313
capga
capping protein (actin filament), gelsolin-like a
chr19_-_8940068 1.95 ENSDART00000043507
ciarta
circadian associated repressor of transcription a
chr15_-_25527580 1.95 ENSDART00000167005
ENSDART00000157498
hif1al
hypoxia-inducible factor 1, alpha subunit, like
chr24_-_40668208 1.94 ENSDART00000171543
smyhc1
slow myosin heavy chain 1
chr11_+_29965822 1.94 ENSDART00000127049
il1fma
interleukin-1 family member A
chr22_-_10570749 1.91 ENSDART00000140736
si:dkey-42i9.6
si:dkey-42i9.6

Network of associatons between targets according to the STRING database.

First level regulatory network of sox19b+sox3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.3 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
1.7 6.7 GO:0055107 Golgi to secretory granule transport(GO:0055107)
1.5 8.8 GO:0003151 outflow tract morphogenesis(GO:0003151)
1.4 4.3 GO:0003156 regulation of organ formation(GO:0003156)
1.4 4.1 GO:0060907 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
1.1 3.3 GO:0070314 G1 to G0 transition(GO:0070314)
1.0 7.8 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.9 4.6 GO:0045056 transcytosis(GO:0045056)
0.9 2.6 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.8 3.4 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.8 4.8 GO:0071405 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.8 4.6 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.8 1.5 GO:0061082 positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081) myeloid leukocyte cytokine production(GO:0061082)
0.7 4.4 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.7 4.8 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.7 3.4 GO:1901207 regulation of heart looping(GO:1901207)
0.6 1.9 GO:0072196 proximal/distal pattern formation involved in nephron development(GO:0072047) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.6 3.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.6 3.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.6 1.7 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.5 2.7 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.5 6.0 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.5 2.1 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.5 2.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.5 3.6 GO:0060017 parathyroid gland development(GO:0060017)
0.5 4.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.5 1.8 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.5 1.8 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.4 3.1 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.4 2.2 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.4 2.2 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.4 1.2 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.4 2.4 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.4 1.6 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.4 3.9 GO:0050819 negative regulation of coagulation(GO:0050819)
0.4 5.8 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.4 1.8 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.3 0.6 GO:0006012 galactose metabolic process(GO:0006012)
0.3 2.7 GO:0042987 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.3 0.9 GO:2000434 regulation of protein neddylation(GO:2000434)
0.3 1.5 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.3 6.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.3 0.9 GO:0007405 neuroblast proliferation(GO:0007405)
0.3 1.1 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.3 2.8 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.3 1.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 1.6 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.3 2.5 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.2 0.7 GO:1903060 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.2 5.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.2 1.2 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.2 10.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 2.6 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.2 2.3 GO:0051601 exocyst localization(GO:0051601)
0.2 3.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 0.7 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.2 2.2 GO:0044030 regulation of DNA methylation(GO:0044030)
0.2 2.4 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.2 0.9 GO:0090579 establishment of mitotic sister chromatid cohesion(GO:0034087) establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 2.7 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.2 0.6 GO:0071042 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.2 2.6 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.2 4.0 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.2 0.8 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.2 2.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 1.9 GO:0001709 cell fate determination(GO:0001709)
0.2 0.5 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.2 1.9 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.2 3.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 1.5 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.2 0.8 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.2 7.4 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.2 1.8 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.2 1.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 8.2 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.2 1.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.2 2.5 GO:0016926 protein desumoylation(GO:0016926)
0.2 1.5 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 3.9 GO:0048570 notochord morphogenesis(GO:0048570)
0.1 0.9 GO:0055016 hypochord development(GO:0055016)
0.1 1.3 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 5.5 GO:0030199 collagen fibril organization(GO:0030199)
0.1 6.3 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 2.6 GO:0006584 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.1 1.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 1.9 GO:0014823 response to activity(GO:0014823)
0.1 1.6 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.1 0.7 GO:2000562 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 5.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 3.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 3.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 12.3 GO:0031101 fin regeneration(GO:0031101)
0.1 1.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.6 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.1 2.8 GO:0003171 atrioventricular valve development(GO:0003171)
0.1 1.8 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.1 1.0 GO:0042664 negative regulation of endodermal cell fate specification(GO:0042664)
0.1 1.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 3.1 GO:0035329 hippo signaling(GO:0035329)
0.1 0.7 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.5 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.1 1.4 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 2.4 GO:0001843 neural tube closure(GO:0001843)
0.1 0.4 GO:0032801 receptor catabolic process(GO:0032801)
0.1 1.3 GO:0035108 limb morphogenesis(GO:0035108)
0.1 1.3 GO:0009409 response to cold(GO:0009409)
0.1 4.8 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043280)
0.1 1.0 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.1 1.5 GO:0097324 melanocyte migration(GO:0097324)
0.1 1.7 GO:0043114 regulation of vascular permeability(GO:0043114)
0.1 1.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 3.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.8 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 5.1 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.1 3.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 1.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.5 GO:0061011 hepatic duct development(GO:0061011)
0.1 2.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.5 GO:0003342 bulbus arteriosus development(GO:0003232) proepicardium development(GO:0003342) septum transversum development(GO:0003343)
0.1 2.2 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 1.9 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 6.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 0.3 GO:1990403 embryonic brain development(GO:1990403)
0.1 1.0 GO:0021654 rhombomere boundary formation(GO:0021654)
0.1 1.8 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.8 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 2.9 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 2.0 GO:0051014 actin filament severing(GO:0051014)
0.1 2.5 GO:0046847 filopodium assembly(GO:0046847)
0.1 0.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.4 GO:1902765 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.1 0.6 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 1.0 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 1.6 GO:0031638 zymogen activation(GO:0031638)
0.1 2.7 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 4.3 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 0.8 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 1.4 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 1.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 1.0 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 1.6 GO:0060037 pharyngeal system development(GO:0060037)
0.1 1.1 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 1.6 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 3.1 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.9 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.8 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.0 0.6 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.2 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.0 0.3 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 0.4 GO:0007314 cytoplasm organization(GO:0007028) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) intracellular mRNA localization(GO:0008298) maternal determination of anterior/posterior axis, embryo(GO:0008358)
0.0 0.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 1.1 GO:0061009 intrahepatic bile duct development(GO:0035622) common bile duct development(GO:0061009)
0.0 3.3 GO:0030048 actin filament-based movement(GO:0030048)
0.0 1.1 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 0.5 GO:0070828 heterochromatin organization(GO:0070828)
0.0 0.3 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 1.2 GO:0019835 cytolysis(GO:0019835)
0.0 3.5 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.3 GO:0015807 L-amino acid transport(GO:0015807)
0.0 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.0 1.0 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.5 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.8 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.5 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.5 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.3 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 1.8 GO:0051607 defense response to virus(GO:0051607)
0.0 0.7 GO:0097352 autophagosome maturation(GO:0097352)
0.0 1.8 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 3.6 GO:0001817 regulation of cytokine production(GO:0001817)
0.0 0.1 GO:0098751 bone cell development(GO:0098751)
0.0 0.8 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 8.3 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.8 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 2.3 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.3 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 1.0 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 3.3 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.2 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 1.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.6 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 2.9 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.6 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 0.6 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.8 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 3.4 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 3.5 GO:0006954 inflammatory response(GO:0006954)
0.0 1.5 GO:0030218 erythrocyte differentiation(GO:0030218) erythrocyte homeostasis(GO:0034101)
0.0 1.4 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.1 GO:0097066 response to thyroid hormone(GO:0097066)
0.0 11.6 GO:0016567 protein ubiquitination(GO:0016567)
0.0 1.9 GO:0006401 RNA catabolic process(GO:0006401)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 1.0 GO:0006910 humoral immune response mediated by circulating immunoglobulin(GO:0002455) phagocytosis, recognition(GO:0006910) complement activation, classical pathway(GO:0006958)
0.0 0.9 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.3 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0060974 cell migration involved in heart formation(GO:0060974)
0.0 0.4 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.9 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 1.0 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 1.1 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 1.4 GO:0009617 response to bacterium(GO:0009617)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 4.6 GO:0006955 immune response(GO:0006955)
0.0 2.6 GO:0016197 endosomal transport(GO:0016197)
0.0 1.6 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.1 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.3 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.7 GO:0006354 DNA-templated transcription, elongation(GO:0006354)
0.0 0.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.3 GO:0006298 mismatch repair(GO:0006298)
0.0 0.2 GO:0046328 regulation of JNK cascade(GO:0046328)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 11.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.9 7.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.7 2.9 GO:0005588 collagen type V trimer(GO:0005588)
0.7 2.0 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.6 7.0 GO:0045095 keratin filament(GO:0045095)
0.5 9.7 GO:0030057 desmosome(GO:0030057)
0.5 6.4 GO:0000815 ESCRT III complex(GO:0000815)
0.4 4.0 GO:0031526 brush border membrane(GO:0031526)
0.4 17.9 GO:0005861 troponin complex(GO:0005861)
0.4 2.0 GO:0097433 dense body(GO:0097433)
0.4 3.1 GO:0061700 GATOR2 complex(GO:0061700)
0.4 1.1 GO:1990077 primosome complex(GO:1990077)
0.3 6.0 GO:0042555 MCM complex(GO:0042555)
0.3 5.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.3 2.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 1.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.2 2.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 2.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 1.7 GO:0071914 prominosome(GO:0071914)
0.2 0.5 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.2 1.1 GO:0071986 Ragulator complex(GO:0071986)
0.2 9.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 3.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 2.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 1.9 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.9 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 1.8 GO:0044545 NSL complex(GO:0044545)
0.1 2.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 3.3 GO:0000145 exocyst(GO:0000145)
0.1 0.8 GO:1990130 Iml1 complex(GO:1990130)
0.1 6.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.8 GO:0000243 commitment complex(GO:0000243)
0.1 0.6 GO:0070062 extracellular exosome(GO:0070062)
0.1 5.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.5 GO:0005839 proteasome core complex(GO:0005839)
0.1 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 1.4 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 4.2 GO:0008305 integrin complex(GO:0008305)
0.1 0.5 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 3.7 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 3.8 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 2.9 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.6 GO:0089701 U2AF(GO:0089701)
0.1 2.8 GO:0090544 BAF-type complex(GO:0090544)
0.1 7.2 GO:0005884 actin filament(GO:0005884)
0.1 0.6 GO:0005771 multivesicular body(GO:0005771)
0.1 2.2 GO:0005581 collagen trimer(GO:0005581)
0.1 0.7 GO:0031010 ISWI-type complex(GO:0031010)
0.1 0.6 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 13.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 18.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0030891 VCB complex(GO:0030891)
0.0 0.7 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 2.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 4.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 4.1 GO:0016607 nuclear speck(GO:0016607)
0.0 0.4 GO:0000792 heterochromatin(GO:0000792)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.4 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.7 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 9.6 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.1 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.0 0.2 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.3 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.5 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 2.0 GO:0005925 focal adhesion(GO:0005925)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.8 GO:0055037 recycling endosome(GO:0055037)
0.0 1.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 2.3 GO:0070161 adherens junction(GO:0005912) anchoring junction(GO:0070161)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.9 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)
0.0 5.7 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.2 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
1.6 4.7 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
1.4 5.6 GO:0071889 14-3-3 protein binding(GO:0071889)
1.3 6.6 GO:0070573 metallodipeptidase activity(GO:0070573)
1.3 6.4 GO:0001223 transcription coactivator binding(GO:0001223)
1.1 3.4 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
1.0 3.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.8 2.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.7 3.6 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.7 6.4 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.7 2.0 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.6 1.8 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.6 1.8 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.5 1.5 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.4 3.1 GO:0070728 leucine binding(GO:0070728)
0.4 3.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.4 2.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.4 4.5 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.4 2.0 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.4 4.3 GO:0005523 tropomyosin binding(GO:0005523)
0.4 4.0 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.4 2.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.4 4.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 12.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 2.4 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 4.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 1.9 GO:0016361 activin receptor activity, type I(GO:0016361)
0.3 9.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 2.3 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 2.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.3 4.8 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.3 5.4 GO:0008301 DNA binding, bending(GO:0008301)
0.3 1.8 GO:0019809 spermidine binding(GO:0019809)
0.3 1.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 4.0 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.2 1.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 2.6 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 1.2 GO:0050699 WW domain binding(GO:0050699)
0.2 0.7 GO:0098808 mRNA cap binding(GO:0098808)
0.2 3.1 GO:0048185 activin binding(GO:0048185)
0.2 1.5 GO:0030274 LIM domain binding(GO:0030274)
0.2 5.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 0.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 2.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.8 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 1.9 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.2 1.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.2 4.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.7 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2 2.1 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.2 8.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 0.6 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 1.0 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 1.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 6.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 2.5 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 2.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.7 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 1.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 8.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 2.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.6 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.1 0.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 1.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 1.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.5 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.9 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.7 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 1.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.8 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 9.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.0 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.8 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 0.6 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 3.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.5 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.5 GO:0034632 retinol transporter activity(GO:0034632)
0.1 4.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.9 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 0.5 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 5.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 2.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 4.4 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 4.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.5 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.7 GO:0016936 galactoside binding(GO:0016936)
0.1 2.4 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 0.8 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.5 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.5 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.6 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 20.7 GO:0051015 actin filament binding(GO:0051015)
0.1 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 3.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 3.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 1.1 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 5.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 5.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 3.1 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.9 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.1 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.2 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.6 GO:0045503 dynein light chain binding(GO:0045503)
0.0 5.2 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 14.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 6.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 4.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.9 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 3.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 14.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.3 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 6.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 3.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.8 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.0 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 2.3 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 4.0 GO:0019901 protein kinase binding(GO:0019901)
0.0 13.1 GO:0005525 GTP binding(GO:0005525)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 1.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.3 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 1.8 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.8 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.6 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.7 GO:0051287 NAD binding(GO:0051287)
0.0 0.7 GO:0003678 DNA helicase activity(GO:0003678)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.5 4.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.3 4.4 PID CONE PATHWAY Visual signal transduction: Cones
0.3 6.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 2.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 6.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 3.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 11.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.2 8.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.6 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 6.4 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.0 PID IL3 PATHWAY IL3-mediated signaling events
0.1 2.6 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 3.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 1.7 PID RHOA PATHWAY RhoA signaling pathway
0.1 1.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.8 PID NOTCH PATHWAY Notch signaling pathway
0.1 0.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 0.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 1.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.6 PID ENDOTHELIN PATHWAY Endothelins
0.1 1.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 1.1 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 3.1 PID E2F PATHWAY E2F transcription factor network
0.0 1.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 3.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID INSULIN PATHWAY Insulin Pathway
0.0 0.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.6 PID ATR PATHWAY ATR signaling pathway
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.1 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.7 6.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5 5.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.5 3.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.4 6.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.4 3.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 2.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.3 1.8 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 3.0 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.3 2.7 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.3 1.4 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.2 1.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 3.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 5.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 3.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.2 1.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.2 1.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 3.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.9 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.1 1.1 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 1.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 3.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 1.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 0.9 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 0.7 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 0.5 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 0.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.5 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 0.8 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 2.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 2.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 2.3 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing