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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for sox4a+sox4b

Z-value: 0.80

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Transcription factors associated with sox4a+sox4b

Gene Symbol Gene ID Gene Info
sox4a
ENSDARG00000004588 SRY-box transcription factor 4a
sox4b
ENSDARG00000098834 SRY-box transcription factor 4b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox4bdr11_v1_chr16_+_68069_681240.617.4e-11Click!
sox4adr11_v1_chr19_-_28789404_287894090.472.3e-06Click!

Activity profile of sox4a+sox4b motif

Sorted Z-values of sox4a+sox4b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_30615901 9.17 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr16_-_9675982 6.51 ENSDART00000113724
mal2
mal, T cell differentiation protein 2 (gene/pseudogene)
chr14_-_8080416 6.31 ENSDART00000045109
zgc:92242
zgc:92242
chr16_-_33104944 5.87 ENSDART00000151943
pnrc2
proline-rich nuclear receptor coactivator 2
chr13_+_22675802 5.47 ENSDART00000145538
ENSDART00000143312
zgc:193505
zgc:193505
chr3_-_27646070 5.32 ENSDART00000122031
ENSDART00000151027
si:ch211-157c3.4
si:ch211-157c3.4
chr5_+_20823409 4.31 ENSDART00000093185
ENSDART00000142894
limk2
LIM domain kinase 2
chr5_-_37117778 4.30 ENSDART00000149138
il13ra2
interleukin 13 receptor, alpha 2
chr5_+_15203421 4.25 ENSDART00000040826
tbx1
T-box 1
chr9_+_48007081 4.14 ENSDART00000060593
ENSDART00000099835
zgc:92380
zgc:92380
chr17_-_5860222 4.10 ENSDART00000058894
si:ch73-340m8.2
si:ch73-340m8.2
chr4_-_16354292 4.04 ENSDART00000139919
lum
lumican
chr8_-_39903803 3.93 ENSDART00000012391
cabp1a
calcium binding protein 1a
chr15_-_12360409 3.72 ENSDART00000164596
tmprss13a
transmembrane protease, serine 13a
chr4_+_18843015 3.65 ENSDART00000152086
ENSDART00000066977
ENSDART00000132567
bik
BCL2 interacting killer
chr23_-_3758637 3.62 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
hmga1a
high mobility group AT-hook 1a
chr17_-_2036850 3.41 ENSDART00000186048
ENSDART00000188838
ENSDART00000186423
spint1a
serine peptidase inhibitor, Kunitz type 1 a
chr1_+_44173245 3.28 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
ctnnd1
catenin (cadherin-associated protein), delta 1
chr19_+_7636941 3.18 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cgnb
cingulin b
chr2_+_45191049 3.17 ENSDART00000165392
ccl20a.3
chemokine (C-C motif) ligand 20a, duplicate 3
chr25_+_35502552 3.12 ENSDART00000189612
ENSDART00000058443
fibina
fin bud initiation factor a
chr7_+_20019125 3.08 ENSDART00000186391
bcl6b
B-cell CLL/lymphoma 6, member B
chr23_-_29824146 2.84 ENSDART00000020616
zgc:194189
zgc:194189
chr22_+_18886209 2.79 ENSDART00000144402
fstl3
follistatin-like 3 (secreted glycoprotein)
chr8_+_46217861 2.78 ENSDART00000038790
angptl7
angiopoietin-like 7
chr18_+_39327010 2.75 ENSDART00000012164
tmod2
tropomodulin 2
chr23_-_3759345 2.73 ENSDART00000132205
ENSDART00000137707
ENSDART00000189382
hmga1a
high mobility group AT-hook 1a
chr1_+_54773877 2.68 ENSDART00000129831
nlrc6
NLR family CARD domain containing 6
chr3_-_16110351 2.59 ENSDART00000064838
lasp1
LIM and SH3 protein 1
chr11_+_29965822 2.57 ENSDART00000127049
il1fma
interleukin-1 family member A
chr12_-_22400999 2.55 ENSDART00000153194
si:dkey-38p12.3
si:dkey-38p12.3
chr21_-_37027252 2.55 ENSDART00000076483
zgc:77151
zgc:77151
chr17_-_8862424 2.53 ENSDART00000064633
nkl.4
NK-lysin tandem duplicate 4
chr11_-_45185792 2.48 ENSDART00000171328
si:dkey-93h22.7
si:dkey-93h22.7
chr13_+_28732101 2.48 ENSDART00000015773
ldb1a
LIM domain binding 1a
chr16_-_49505275 2.44 ENSDART00000160784
satb1b
SATB homeobox 1b
chr24_-_33756003 2.42 ENSDART00000079283
tmeff1b
transmembrane protein with EGF-like and two follistatin-like domains 1b
chr20_+_6533260 2.42 ENSDART00000135005
ENSDART00000166356
si:ch211-191a24.4
si:ch211-191a24.4
chr3_-_16110100 2.41 ENSDART00000051807
lasp1
LIM and SH3 protein 1
chr9_+_25330905 2.40 ENSDART00000101470
itm2bb
integral membrane protein 2Bb
chr6_+_12968101 2.38 ENSDART00000013781
mcm6
minichromosome maintenance complex component 6
chr2_+_5300405 2.38 ENSDART00000019925
GNB4
G protein subunit beta 4
chr3_+_56645710 2.30 ENSDART00000193978
CR759836.1

chr5_-_46505691 2.23 ENSDART00000111589
ENSDART00000122966
ENSDART00000166907
hapln1a
hyaluronan and proteoglycan link protein 1a
chr20_+_34770197 2.16 ENSDART00000018304
mcm3
minichromosome maintenance complex component 3
chr6_-_8244474 2.12 ENSDART00000151358
rgl3a
ral guanine nucleotide dissociation stimulator-like 3a
chr24_+_21973929 2.12 ENSDART00000042495
sat1b
spermidine/spermine N1-acetyltransferase 1b
chr6_-_6976096 2.11 ENSDART00000151822
ENSDART00000039443
ENSDART00000177960
tuba8l4
tubulin, alpha 8 like 4
chr16_+_29586468 2.09 ENSDART00000148926
mcl1b
MCL1, BCL2 family apoptosis regulator b
chr1_-_23308225 2.08 ENSDART00000137567
ENSDART00000008201
smim14
small integral membrane protein 14
chr10_+_20113830 2.04 ENSDART00000139722
dmtn
dematin actin binding protein
chr21_+_26389391 2.04 ENSDART00000077197
tmsb
thymosin, beta
chr8_-_28349859 2.03 ENSDART00000062671
tuba8l
tubulin, alpha 8 like
chr8_+_30797363 2.02 ENSDART00000077280
mmp11a
matrix metallopeptidase 11a
chr18_+_30998472 1.99 ENSDART00000154993
ENSDART00000099333
cd151l
CD151 antigen, like
chr15_-_15469079 1.95 ENSDART00000132637
ENSDART00000004220
rab34a
RAB34, member RAS oncogene family a
chr7_-_28413224 1.95 ENSDART00000076502
rerglb
RERG/RAS-like b
chr22_-_10354381 1.92 ENSDART00000092050
stab1
stabilin 1
chr8_+_4803906 1.89 ENSDART00000045533
tmem127
transmembrane protein 127
chr3_-_36364903 1.85 ENSDART00000028883
gna13b
guanine nucleotide binding protein (G protein), alpha 13b
chr22_-_7025393 1.84 ENSDART00000003422
smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr19_-_15855427 1.82 ENSDART00000133059
cited4a
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a
chr14_+_33525196 1.81 ENSDART00000085335
zdhhc9
zinc finger, DHHC-type containing 9
chr1_+_44173506 1.80 ENSDART00000170512
ctnnd1
catenin (cadherin-associated protein), delta 1
chr14_-_33095917 1.74 ENSDART00000074720
dlg3
discs, large homolog 3 (Drosophila)
chr15_+_37331585 1.72 ENSDART00000170715
zgc:171592
zgc:171592
chr5_+_23045096 1.70 ENSDART00000171719
atrxl
alpha thalassemia/mental retardation syndrome X-linked, like
chr5_+_31480342 1.69 ENSDART00000098197
si:dkey-220k22.1
si:dkey-220k22.1
chr6_+_8176486 1.66 ENSDART00000193308
nfil3-5
nuclear factor, interleukin 3 regulated, member 5
chr6_+_59832786 1.65 ENSDART00000154985
ENSDART00000102148
ddx3b
DEAD (Asp-Glu-Ala-Asp) box helicase 3b
chr13_-_21650404 1.63 ENSDART00000078352
tspan14
tetraspanin 14
chr12_-_28848015 1.63 ENSDART00000153200
si:ch211-194k22.8
si:ch211-194k22.8
chr15_+_12429206 1.61 ENSDART00000168997
tmprss4a
transmembrane protease, serine 4a
chr23_+_42819221 1.60 ENSDART00000180495
myl9a
myosin, light chain 9a, regulatory
chr12_+_10115964 1.59 ENSDART00000152369
si:dkeyp-118b1.2
si:dkeyp-118b1.2
chr10_+_29849977 1.59 ENSDART00000180242
hspa8
heat shock protein 8
chr17_+_44030692 1.56 ENSDART00000049503
peli2
pellino E3 ubiquitin protein ligase family member 2
chr25_-_12902242 1.55 ENSDART00000164733
sept15
septin 15
chr19_+_7424347 1.55 ENSDART00000004622
sf3b4
splicing factor 3b, subunit 4
chr7_-_55454406 1.55 ENSDART00000108646
piezo1
piezo-type mechanosensitive ion channel component 1
chr1_-_9652547 1.54 ENSDART00000016750
ENSDART00000127735
ENSDART00000160474
ENSDART00000080323
ENSDART00000126996
ENSDART00000126877
ENSDART00000123773
ugt5b3
ugt5b2
ugt5b3
ugt5b1
UDP glucuronosyltransferase 5 family, polypeptide B3
UDP glucuronosyltransferase 5 family, polypeptide B2
UDP glucuronosyltransferase 5 family, polypeptide B3
UDP glucuronosyltransferase 5 family, polypeptide B1
chr22_-_15693085 1.51 ENSDART00000141861
si:ch1073-396h14.1
si:ch1073-396h14.1
chr21_+_25071805 1.50 ENSDART00000078651
dixdc1b
DIX domain containing 1b
chr10_-_25628555 1.49 ENSDART00000143978
tiam1a
T cell lymphoma invasion and metastasis 1a
chr19_-_17774875 1.49 ENSDART00000151133
ENSDART00000130695
top2b
DNA topoisomerase II beta
chr18_-_7481036 1.49 ENSDART00000101292
si:dkey-238c7.16
si:dkey-238c7.16
chr2_+_18988407 1.49 ENSDART00000170216
glula
glutamate-ammonia ligase (glutamine synthase) a
chr18_+_8231138 1.48 ENSDART00000140193
arsa
arylsulfatase A
chr7_-_26408472 1.46 ENSDART00000111494
gal3st4
galactose-3-O-sulfotransferase 4
chr12_+_48340133 1.46 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
ddit4
DNA-damage-inducible transcript 4
chr21_-_32781612 1.45 ENSDART00000031028
cnot6a
CCR4-NOT transcription complex, subunit 6a
chr2_-_24069331 1.43 ENSDART00000156972
ENSDART00000181691
ENSDART00000157041
slc12a7a
solute carrier family 12 (potassium/chloride transporter), member 7a
chr15_+_28368823 1.42 ENSDART00000142298
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr22_+_4443689 1.42 ENSDART00000185490
ticam1
toll-like receptor adaptor molecule 1
chr12_-_20616160 1.39 ENSDART00000105362
snx11
sorting nexin 11
chr1_+_54834119 1.39 ENSDART00000140020
si:ch211-196h16.4
si:ch211-196h16.4
chr16_-_38001040 1.36 ENSDART00000133861
ENSDART00000138711
ENSDART00000143846
ENSDART00000146564
si:ch211-198c19.3
si:ch211-198c19.3
chr15_+_28368644 1.34 ENSDART00000168453
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr9_-_8670158 1.31 ENSDART00000077296
col4a1
collagen, type IV, alpha 1
chr22_-_22337382 1.29 ENSDART00000144684
si:ch211-129c21.1
si:ch211-129c21.1
chr23_-_36306337 1.28 ENSDART00000142760
ENSDART00000136929
ENSDART00000143340
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr5_+_41477954 1.28 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr10_-_36633882 1.28 ENSDART00000077161
ENSDART00000137688
rsf1b.1
rsf1b.1
remodeling and spacing factor 1b, tandem duplicate 1
remodeling and spacing factor 1b, tandem duplicate 1
chr8_+_29636431 1.27 ENSDART00000133047
smarcad1a
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr11_-_183328 1.27 ENSDART00000168562
avil
advillin
chr9_+_54179306 1.26 ENSDART00000189829
tmsb4x
thymosin, beta 4 x
chr6_-_40768654 1.26 ENSDART00000184668
ENSDART00000146470
arpc4
actin related protein 2/3 complex, subunit 4
chr1_+_24076243 1.25 ENSDART00000014608
mab21l2
mab-21-like 2
chr14_+_6962271 1.25 ENSDART00000148447
ENSDART00000149114
ENSDART00000149492
ENSDART00000148394
hnrnpaba
heterogeneous nuclear ribonucleoprotein A/Ba
chr6_-_19351495 1.25 ENSDART00000164287
grb2a
growth factor receptor-bound protein 2a
chr19_+_40026959 1.24 ENSDART00000123647
sfpq
splicing factor proline/glutamine-rich
chr5_-_32383475 1.23 ENSDART00000141294
fbxw2
F-box and WD repeat domain containing 2
chr19_-_46037835 1.23 ENSDART00000163815
nup153
nucleoporin 153
chr6_-_40098641 1.21 ENSDART00000017402
ip6k2b
inositol hexakisphosphate kinase 2b
chr6_-_9707599 1.21 ENSDART00000039280
fzd7b
frizzled class receptor 7b
chr19_-_30800004 1.21 ENSDART00000128560
ENSDART00000045504
ENSDART00000125893
trit1
tRNA isopentenyltransferase 1
chr6_+_46406565 1.20 ENSDART00000168440
ENSDART00000131203
ENSDART00000138567
ENSDART00000132845
pbrm1l
polybromo 1, like
chr14_+_6963312 1.19 ENSDART00000150050
hnrnpaba
heterogeneous nuclear ribonucleoprotein A/Ba
chr23_+_25428513 1.18 ENSDART00000144554
fmnl3
formin-like 3
chr3_-_21348478 1.18 ENSDART00000114906
fam171a2a
family with sequence similarity 171, member A2a
chr2_-_3038904 1.18 ENSDART00000186795
guk1a
guanylate kinase 1a
chr17_+_20504196 1.17 ENSDART00000190539
neurl1ab
neuralized E3 ubiquitin protein ligase 1Ab
chr11_+_807153 1.13 ENSDART00000173289
vgll4b
vestigial-like family member 4b
chr22_-_22301672 1.13 ENSDART00000111711
chaf1a
chromatin assembly factor 1, subunit A (p150)
chr22_+_28446365 1.12 ENSDART00000189359
abi3bpb
ABI family, member 3 (NESH) binding protein b
chr8_-_51340773 1.12 ENSDART00000060633
kansl3
KAT8 regulatory NSL complex subunit 3
chr1_+_5485799 1.11 ENSDART00000022307
atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr17_+_24632440 1.10 ENSDART00000157092
map4k3b
mitogen-activated protein kinase kinase kinase kinase 3b
chr12_-_30777743 1.10 ENSDART00000148888
entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr13_+_39188737 1.09 ENSDART00000083641
fam135a
family with sequence similarity 135, member A
chr11_-_2250767 1.09 ENSDART00000018131
hnrnpa1a
heterogeneous nuclear ribonucleoprotein A1a
chr6_-_59505589 1.06 ENSDART00000170685
gli1
GLI family zinc finger 1
chr13_-_33317323 1.04 ENSDART00000110295
ENSDART00000144848
ENSDART00000136701
tmem234
transmembrane protein 234
chr15_-_4094888 1.04 ENSDART00000166307
TM4SF19
si:dkey-83h2.3
chr2_-_7696287 1.04 ENSDART00000190769
CABZ01055306.1

chr15_+_34963316 1.03 ENSDART00000153840
si:ch73-95l15.5
si:ch73-95l15.5
chr5_+_41477526 1.03 ENSDART00000153567
pias2
protein inhibitor of activated STAT, 2
chr20_-_33790003 1.03 ENSDART00000020183
fam102bb
family with sequence similarity 102, member B, b
chr10_-_2788668 1.02 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2l
ash2 (absent, small, or homeotic)-like (Drosophila)
chr10_+_29849497 1.02 ENSDART00000099994
ENSDART00000132212
hspa8
heat shock protein 8
chr25_+_34862225 1.02 ENSDART00000149782
CHST6
zgc:194879
chr6_+_7322587 1.01 ENSDART00000065500
abcc4
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr3_+_52999962 1.01 ENSDART00000104683
pbx4
pre-B-cell leukemia transcription factor 4
chr15_-_15468326 1.01 ENSDART00000161192
rab34a
RAB34, member RAS oncogene family a
chr7_-_24149670 1.00 ENSDART00000005884
mmp14a
matrix metallopeptidase 14a (membrane-inserted)
chr19_+_24575077 1.00 ENSDART00000167469
si:dkeyp-92c9.4
si:dkeyp-92c9.4
chr3_+_3545825 0.99 ENSDART00000109060
CR589947.1

chr8_-_51340931 0.98 ENSDART00000178209
kansl3
KAT8 regulatory NSL complex subunit 3
chr2_+_2967255 0.98 ENSDART00000167649
ENSDART00000166449
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr24_+_17142881 0.98 ENSDART00000177272
ENSDART00000192259
ENSDART00000191029
mllt10
MLLT10, histone lysine methyltransferase DOT1L cofactor
chr14_-_31151148 0.98 ENSDART00000026569
gpc4
glypican 4
chr13_+_25422009 0.94 ENSDART00000057686
calhm2
calcium homeostasis modulator 2
chr22_+_12161738 0.94 ENSDART00000168857
ccnt2b
cyclin T2b
chr8_-_19467011 0.94 ENSDART00000162010
zgc:92140
zgc:92140
chr20_+_26881600 0.94 ENSDART00000174799
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr20_-_25533739 0.93 ENSDART00000063064
cyp2ad6
cytochrome P450, family 2, subfamily AD, polypeptide 6
chr5_-_38179220 0.93 ENSDART00000147701
si:ch211-284e13.11
si:ch211-284e13.11
chr9_-_36924388 0.93 ENSDART00000059756
ralba
v-ral simian leukemia viral oncogene homolog Ba (ras related)
chr5_-_8096232 0.93 ENSDART00000158447
nipbla
nipped-B homolog a (Drosophila)
chr25_+_31323978 0.91 ENSDART00000067030
lsp1
lymphocyte-specific protein 1
chr4_+_13953537 0.90 ENSDART00000133596
pphln1
periphilin 1
chr22_+_8979955 0.89 ENSDART00000144005
si:ch211-213a13.1
si:ch211-213a13.1
chr3_+_34985895 0.89 ENSDART00000121981
smarce1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr5_-_22602979 0.89 ENSDART00000146287
nono
non-POU domain containing, octamer-binding
chr21_+_26748141 0.89 ENSDART00000169025
pcxa
pyruvate carboxylase a
chr23_+_9088191 0.88 ENSDART00000030811
cables2b
Cdk5 and Abl enzyme substrate 2b
chr24_-_35707552 0.88 ENSDART00000165199
mapre2
microtubule-associated protein, RP/EB family, member 2
chr10_-_1697037 0.87 ENSDART00000125188
ENSDART00000002985
srsf9
serine/arginine-rich splicing factor 9
chr4_-_15003854 0.87 ENSDART00000134701
ENSDART00000002401
klhdc10
kelch domain containing 10
chr3_+_60761811 0.85 ENSDART00000053482
tsen54
TSEN54 tRNA splicing endonuclease subunit
chr5_+_19448078 0.85 ENSDART00000088968
ube3b
ubiquitin protein ligase E3B
chr7_+_44713135 0.84 ENSDART00000170721
si:dkey-56m19.5
si:dkey-56m19.5
chr11_+_11152214 0.83 ENSDART00000148030
ly75
lymphocyte antigen 75
chr14_-_2004291 0.83 ENSDART00000114039
pcdh2g5
protocadherin 2 gamma 5
chr19_-_29853402 0.82 ENSDART00000024292
ENSDART00000188508
txlna
taxilin alpha
chr24_-_31194847 0.82 ENSDART00000158808
cnn3a
calponin 3, acidic a
chr24_-_12983829 0.82 ENSDART00000133324
dcaf11
ddb1 and cul4 associated factor 11
chr9_-_32142311 0.82 ENSDART00000142768
ankrd44
ankyrin repeat domain 44
chr1_+_41609254 0.82 ENSDART00000132189
mogs
mannosyl-oligosaccharide glucosidase
chr13_+_25421531 0.82 ENSDART00000158093
calhm2
calcium homeostasis modulator 2
chr22_+_14117078 0.81 ENSDART00000013575
bzw1a
basic leucine zipper and W2 domains 1a
chr23_-_16682186 0.81 ENSDART00000020810
sdcbp2
syndecan binding protein (syntenin) 2
chr5_+_36900157 0.81 ENSDART00000183533
ENSDART00000051184
hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr5_-_24231139 0.81 ENSDART00000143492
senp3a
SUMO1/sentrin/SMT3 specific peptidase 3a
chr10_-_17284055 0.80 ENSDART00000167464
GNAZ
G protein subunit alpha z
chr16_-_33105677 0.79 ENSDART00000145055
pnrc2
proline-rich nuclear receptor coactivator 2
chr24_-_6345647 0.78 ENSDART00000108994
zgc:174877
zgc:174877
chr19_+_43969363 0.78 ENSDART00000051712
gatad1
GATA zinc finger domain containing 1
chr6_+_7249531 0.78 ENSDART00000125912
ENSDART00000083424
ENSDART00000049695
ENSDART00000136088
dzip1
DAZ interacting zinc finger protein 1
chr7_+_22801465 0.77 ENSDART00000052862
ENSDART00000173633
rbm4.1
RNA binding motif protein 4.1
chr5_+_25317061 0.77 ENSDART00000170097
trpm6
transient receptor potential cation channel, subfamily M, member 6
chr16_-_54919260 0.76 ENSDART00000156533
kdf1a
keratinocyte differentiation factor 1a
chr12_-_30777540 0.75 ENSDART00000126466
entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr15_-_6976851 0.75 ENSDART00000158474
ENSDART00000168943
ENSDART00000169944
si:ch73-311h14.2
si:ch73-311h14.2
chr24_-_6345965 0.74 ENSDART00000178287
zgc:174877
zgc:174877
chr12_+_19320657 0.73 ENSDART00000100075
ENSDART00000066389
tmem184ba
transmembrane protein 184ba
chr16_+_25068576 0.73 ENSDART00000125838
im:7147486
im:7147486
chr12_-_20120702 0.73 ENSDART00000153387
ENSDART00000158412
ENSDART00000112768
ubald1a
UBA-like domain containing 1a
chr2_-_57264262 0.72 ENSDART00000183815
ENSDART00000149829
ENSDART00000088508
ENSDART00000149508
mbd3a
methyl-CpG binding domain protein 3a
chr22_-_33916620 0.72 ENSDART00000191276
CR974456.1

Network of associatons between targets according to the STRING database.

First level regulatory network of sox4a+sox4b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0003156 regulation of organ formation(GO:0003156)
1.3 6.5 GO:0045056 transcytosis(GO:0045056)
0.6 2.4 GO:1903019 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.5 2.1 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.5 2.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.5 1.9 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.5 1.4 GO:0035666 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.5 1.9 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.5 2.3 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.4 2.6 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.4 4.5 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.4 3.0 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.4 1.1 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.3 1.6 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.3 1.9 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.3 2.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 1.5 GO:0007412 axon target recognition(GO:0007412)
0.3 0.8 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.3 1.3 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.3 2.8 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 5.1 GO:0008078 mesodermal cell migration(GO:0008078)
0.2 2.1 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.2 0.9 GO:0071169 establishment of mitotic sister chromatid cohesion(GO:0034087) establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 6.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.2 2.0 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.2 1.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 1.8 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.2 7.4 GO:0030199 collagen fibril organization(GO:0030199)
0.2 0.9 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.2 1.0 GO:0003232 bulbus arteriosus development(GO:0003232)
0.2 0.5 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.2 1.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 1.2 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.1 2.1 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 1.3 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.1 0.5 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 1.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.9 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 1.3 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.9 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.9 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.1 0.9 GO:0003160 endocardium morphogenesis(GO:0003160)
0.1 2.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 1.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.3 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 2.3 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.9 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 2.4 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.5 GO:0080009 mRNA methylation(GO:0080009)
0.1 2.3 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 3.2 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 1.0 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 3.3 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 2.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 1.0 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 2.8 GO:0015807 L-amino acid transport(GO:0015807)
0.1 3.6 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043280)
0.1 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.7 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 1.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 1.8 GO:0035329 hippo signaling(GO:0035329)
0.1 1.0 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.1 0.5 GO:0030851 granulocyte differentiation(GO:0030851)
0.1 1.5 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.5 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 1.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.8 GO:0016926 protein desumoylation(GO:0016926)
0.0 1.8 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.0 0.7 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 6.6 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 1.0 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 1.9 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 1.3 GO:0051014 actin filament severing(GO:0051014)
0.0 1.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.0 0.4 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.9 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.7 GO:0031638 zymogen activation(GO:0031638)
0.0 1.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 1.0 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.5 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.6 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 1.7 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.5 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 4.0 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 1.5 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 4.1 GO:0045087 innate immune response(GO:0045087)
0.0 2.2 GO:0031101 fin regeneration(GO:0031101)
0.0 0.9 GO:0070304 positive regulation of stress-activated MAPK cascade(GO:0032874) positive regulation of stress-activated protein kinase signaling cascade(GO:0070304)
0.0 0.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.7 GO:0061386 closure of optic fissure(GO:0061386)
0.0 2.9 GO:0001817 regulation of cytokine production(GO:0001817)
0.0 1.2 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 1.1 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.0 0.2 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.4 GO:0034508 centromere complex assembly(GO:0034508)
0.0 2.5 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 1.3 GO:0071599 otic vesicle development(GO:0071599)
0.0 0.5 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.5 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 1.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.6 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 1.1 GO:0006400 tRNA modification(GO:0006400)
0.0 3.3 GO:0006955 immune response(GO:0006955)
0.0 0.7 GO:0051225 spindle assembly(GO:0051225)
0.0 0.6 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.8 GO:0007416 synapse assembly(GO:0007416)
0.0 0.4 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.1 GO:0014812 muscle cell migration(GO:0014812)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.4 1.3 GO:0031213 RSF complex(GO:0031213)
0.3 1.1 GO:0033186 CAF-1 complex(GO:0033186)
0.3 1.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.3 4.5 GO:0042555 MCM complex(GO:0042555)
0.2 0.8 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 1.9 GO:0031526 brush border membrane(GO:0031526)
0.2 1.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 0.5 GO:0032301 MutSalpha complex(GO:0032301)
0.2 2.5 GO:0071564 npBAF complex(GO:0071564)
0.1 2.1 GO:0044545 NSL complex(GO:0044545)
0.1 0.5 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.5 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.4 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.9 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 0.8 GO:0016586 RSC complex(GO:0016586)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 6.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.1 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 1.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 1.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 5.8 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.8 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.7 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 1.8 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 1.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 2.8 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.9 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 3.4 GO:0005882 intermediate filament(GO:0005882)
0.0 4.5 GO:0005925 focal adhesion(GO:0005925)
0.0 4.6 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 4.1 GO:0016607 nuclear speck(GO:0016607)
0.0 4.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 3.2 GO:0005604 basement membrane(GO:0005604)
0.0 3.2 GO:0043296 bicellular tight junction(GO:0005923) apical junction complex(GO:0043296) occluding junction(GO:0070160)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 4.2 GO:0005912 adherens junction(GO:0005912)
0.0 1.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.5 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)
0.0 5.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 2.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 1.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 3.0 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.8 GO:0031674 I band(GO:0031674)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.5 1.5 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.5 2.4 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.4 6.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.4 1.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.4 2.5 GO:0030274 LIM domain binding(GO:0030274)
0.3 1.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.3 2.1 GO:0019809 spermidine binding(GO:0019809)
0.3 0.9 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.3 0.8 GO:0045545 syndecan binding(GO:0045545)
0.2 1.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 1.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 1.5 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 1.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 2.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 2.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 3.3 GO:0003785 actin monomer binding(GO:0003785)
0.2 1.5 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.2 0.5 GO:0032143 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.1 2.8 GO:0048185 activin binding(GO:0048185)
0.1 2.8 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1 0.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.7 GO:0017040 ceramidase activity(GO:0017040)
0.1 1.9 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 2.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.9 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 3.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.2 GO:0005521 lamin binding(GO:0005521)
0.1 0.6 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.7 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 1.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 2.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 4.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.8 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 1.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.1 GO:0015926 glucosidase activity(GO:0015926)
0.0 1.5 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 4.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 4.4 GO:0019955 cytokine binding(GO:0019955)
0.0 3.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 2.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.6 GO:0042379 chemokine activity(GO:0008009) chemokine receptor binding(GO:0042379)
0.0 4.5 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 1.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 9.4 GO:0051015 actin filament binding(GO:0051015)
0.0 5.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 10.7 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 3.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 3.7 GO:0003774 motor activity(GO:0003774)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.7 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 1.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 3.7 GO:0003682 chromatin binding(GO:0003682)
0.0 2.2 GO:0060090 binding, bridging(GO:0060090)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 3.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 5.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 4.3 PID RHOA PATHWAY RhoA signaling pathway
0.2 2.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 4.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 0.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.6 PID E2F PATHWAY E2F transcription factor network
0.0 3.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 2.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 4.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.3 4.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.3 1.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 5.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 2.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 1.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 2.4 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.1 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 1.0 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 1.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.9 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 1.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing