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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for sp1

Z-value: 2.07

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Transcription factors associated with sp1

Gene Symbol Gene ID Gene Info
sp1
ENSDARG00000088347 sp1 transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sp1dr11_v1_chr11_-_28747_287470.161.4e-01Click!

Activity profile of sp1 motif

Sorted Z-values of sp1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_5254699 29.85 ENSDART00000081951
stx1b
syntaxin 1B
chr13_+_1100197 23.87 ENSDART00000139560
ppp3r1a
protein phosphatase 3, regulatory subunit B, alpha a
chr8_-_4618653 23.70 ENSDART00000025535
sept5a
septin 5a
chr7_+_568819 22.91 ENSDART00000173716
nrxn2b
neurexin 2b
chr2_+_58221163 22.80 ENSDART00000157939
FO704813.1

chr21_+_26697536 22.12 ENSDART00000004109
gng3
guanine nucleotide binding protein (G protein), gamma 3
chr7_+_73630751 20.88 ENSDART00000159745
PCP4L1
si:dkey-46i9.1
chr15_-_47956388 20.20 ENSDART00000116506
si:ch1073-111c8.3
si:ch1073-111c8.3
chr3_-_62380146 19.79 ENSDART00000155853
gprc5ba
G protein-coupled receptor, class C, group 5, member Ba
chr11_-_32723851 18.65 ENSDART00000155592
pcdh17
protocadherin 17
chr7_+_7630409 18.11 ENSDART00000172934
clcn3
chloride channel 3
chr16_-_44399335 16.01 ENSDART00000165058
rims2a
regulating synaptic membrane exocytosis 2a
chr8_+_7359294 15.42 ENSDART00000121708
pcsk1nl
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr10_-_31782616 15.16 ENSDART00000128839
fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr22_+_12366516 14.84 ENSDART00000157802
r3hdm1
R3H domain containing 1
chr11_+_25112269 14.80 ENSDART00000147546
ndrg3a
ndrg family member 3a
chr22_+_5574952 14.79 ENSDART00000171774
zgc:171566
zgc:171566
chr2_-_44282796 14.57 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
mpz
myelin protein zero
chr11_+_25064519 14.53 ENSDART00000016181
ndrg3a
ndrg family member 3a
chr1_-_14233815 14.35 ENSDART00000044896
camk2d2
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr1_-_10647484 14.12 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
si:dkey-31e10.1
chr9_-_44295071 13.99 ENSDART00000011837
neurod1
neuronal differentiation 1
chr1_-_18803919 13.72 ENSDART00000020970
pgm2
phosphoglucomutase 2
chr3_+_24361096 13.58 ENSDART00000132387
pvalb6
parvalbumin 6
chr1_-_26782573 13.45 ENSDART00000090611
sh3gl2a
SH3 domain containing GRB2 like 2a, endophilin A1
chr1_-_59176949 13.44 ENSDART00000128742
CABZ01118678.1

chr1_-_10647307 13.34 ENSDART00000103548
si:dkey-31e10.1
si:dkey-31e10.1
chr17_+_15433518 13.21 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr17_-_43466317 13.10 ENSDART00000155313
hspa4l
heat shock protein 4 like
chr17_+_15433671 12.97 ENSDART00000149568
fabp7a
fatty acid binding protein 7, brain, a
chr4_-_5764255 12.96 ENSDART00000113864
faxca
failed axon connections homolog a
chr19_+_33701558 12.94 ENSDART00000147226
runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_24177006 12.86 ENSDART00000132582
map4l
microtubule associated protein 4 like
chr1_-_39943596 12.81 ENSDART00000149730
stox2a
storkhead box 2a
chr19_+_30633453 12.69 ENSDART00000052124
fam49al
family with sequence similarity 49, member A-like
chr9_-_296169 12.51 ENSDART00000165228
kif5aa
kinesin family member 5A, a
chr11_+_25111846 12.40 ENSDART00000128705
ENSDART00000190058
ndrg3a
ndrg family member 3a
chr19_-_7450796 12.32 ENSDART00000104750
mllt11
MLLT11, transcription factor 7 cofactor
chr1_-_12278522 12.25 ENSDART00000142122
ENSDART00000003825
cplx2l
complexin 2, like
chr2_-_22535 12.24 ENSDART00000157877
CABZ01092282.1

chr10_+_15777258 12.19 ENSDART00000140511
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr12_-_25916530 12.13 ENSDART00000186386
sncgb
synuclein, gamma b (breast cancer-specific protein 1)
chr11_-_103136 12.07 ENSDART00000173308
ENSDART00000162982
elmo2
engulfment and cell motility 2
chr10_+_15777064 11.98 ENSDART00000114483
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr1_+_10720294 11.96 ENSDART00000139387
atp1b1b
ATPase Na+/K+ transporting subunit beta 1b
chr23_+_44732863 11.96 ENSDART00000160044
ENSDART00000172268
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr18_-_38087875 11.91 ENSDART00000111301
luzp2
leucine zipper protein 2
chr13_+_421231 11.87 ENSDART00000188212
ENSDART00000017854
lgi1a
leucine-rich, glioma inactivated 1a
chr25_-_13363286 11.86 ENSDART00000163735
ENSDART00000169119
ndrg4
NDRG family member 4
chr16_+_10318893 11.82 ENSDART00000055380
tubb5
tubulin, beta 5
chr2_-_31936966 11.82 ENSDART00000169484
ENSDART00000192492
ENSDART00000027689
amph
amphiphysin
chr13_+_4405282 11.74 ENSDART00000148280
prr18
proline rich 18
chr8_-_30979494 11.69 ENSDART00000138959
si:ch211-251j10.3
si:ch211-251j10.3
chr13_+_12045758 11.58 ENSDART00000079398
ENSDART00000165467
ENSDART00000165880
gng2
guanine nucleotide binding protein (G protein), gamma 2
chr22_-_11493236 11.55 ENSDART00000002691
tspan7b
tetraspanin 7b
chr2_+_24868010 11.48 ENSDART00000078838
rab3aa
RAB3A, member RAS oncogene family, a
chr5_-_13086616 11.46 ENSDART00000051664
ypel1
yippee-like 1
chr25_+_21324588 11.45 ENSDART00000151842
lrrn3a
leucine rich repeat neuronal 3a
chr2_-_9646857 11.40 ENSDART00000056901
zgc:153615
zgc:153615
chr6_+_34512313 11.31 ENSDART00000102554
lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr17_-_20711735 11.29 ENSDART00000150056
ank3b
ankyrin 3b
chr9_+_35860975 11.25 ENSDART00000134447
rcan1a
regulator of calcineurin 1a
chr20_+_33294428 11.24 ENSDART00000024104
mycn
MYCN proto-oncogene, bHLH transcription factor
chr8_-_14052349 11.20 ENSDART00000135811
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr16_+_7626535 11.16 ENSDART00000182670
ENSDART00000065514
ENSDART00000150212
stx12l
syntaxin 12, like
chr14_-_30642819 11.09 ENSDART00000078154
npas4a
neuronal PAS domain protein 4a
chr8_+_23165749 11.06 ENSDART00000063057
dnajc5aa
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr1_-_44704261 10.99 ENSDART00000133210
si:dkey-28b4.8
si:dkey-28b4.8
chr7_+_529522 10.69 ENSDART00000190811
nrxn2b
neurexin 2b
chr10_+_20128267 10.49 ENSDART00000064615
dmtn
dematin actin binding protein
chr7_-_52876683 10.36 ENSDART00000172910
map1aa
microtubule-associated protein 1Aa
chr23_+_45579497 10.22 ENSDART00000110381
egr4
early growth response 4
chr13_+_13693722 10.19 ENSDART00000110509
si:ch211-194c3.5
si:ch211-194c3.5
chr19_+_29798064 10.16 ENSDART00000167803
ENSDART00000051804
marcksl1b
MARCKS-like 1b
chr16_-_44349845 10.14 ENSDART00000170932
rims2a
regulating synaptic membrane exocytosis 2a
chr13_+_36764715 10.13 ENSDART00000111832
ENSDART00000085230
atl1
atlastin GTPase 1
chr19_+_31771270 10.12 ENSDART00000147474
stmn2b
stathmin 2b
chr17_+_15535501 10.05 ENSDART00000002932
marcksb
myristoylated alanine-rich protein kinase C substrate b
chr1_+_54908895 9.99 ENSDART00000145652
golga7ba
golgin A7 family, member Ba
chr10_+_22012389 9.98 ENSDART00000035188
kcnip1b
Kv channel interacting protein 1 b
chr11_-_97817 9.92 ENSDART00000092903
elmo2
engulfment and cell motility 2
chr9_+_22677503 9.91 ENSDART00000131429
ENSDART00000080005
ENSDART00000101756
ENSDART00000138148
itgb5
integrin, beta 5
chr10_+_32561317 9.87 ENSDART00000109029
map6a
microtubule-associated protein 6a
chr20_-_19422496 9.86 ENSDART00000143658
si:ch211-278j3.3
si:ch211-278j3.3
chr1_-_14234076 9.86 ENSDART00000040049
camk2d2
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr8_-_25011157 9.73 ENSDART00000078795
ahcyl1
adenosylhomocysteinase-like 1
chr6_+_32326074 9.71 ENSDART00000042134
ENSDART00000181177
dock7
dedicator of cytokinesis 7
chr3_+_22578369 9.70 ENSDART00000187695
ENSDART00000182678
ENSDART00000112270
tanc2a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2a
chr20_-_34868814 9.67 ENSDART00000153049
stmn4
stathmin-like 4
chr21_-_43079161 9.66 ENSDART00000144151
jakmip2
janus kinase and microtubule interacting protein 2
chr20_-_39219537 9.64 ENSDART00000005764
cyp39a1
cytochrome P450, family 39, subfamily A, polypeptide 1
chr13_+_11439486 9.64 ENSDART00000138312
zbtb18
zinc finger and BTB domain containing 18
chr18_-_38088099 9.64 ENSDART00000146120
luzp2
leucine zipper protein 2
chr20_-_31905968 9.57 ENSDART00000142806
stxbp5a
syntaxin binding protein 5a (tomosyn)
chr12_-_37449396 9.56 ENSDART00000152951
cdc42ep4b
CDC42 effector protein (Rho GTPase binding) 4b
chr6_-_13408680 9.55 ENSDART00000151566
fmnl2b
formin-like 2b
chr23_-_4775446 9.49 ENSDART00000067531
syn2a
synapsin IIa
chr3_-_15264698 9.47 ENSDART00000111948
ENSDART00000142594
sez6l2
seizure related 6 homolog (mouse)-like 2
chr5_+_64739762 9.44 ENSDART00000161112
ENSDART00000135610
ENSDART00000002908
olfm1a
olfactomedin 1a
chr16_-_52733384 9.43 ENSDART00000147236
ENSDART00000056101
azin1a
antizyme inhibitor 1a
chr10_-_32851847 9.43 ENSDART00000134255
trim37
tripartite motif containing 37
chr12_-_14211293 9.39 ENSDART00000158399
avl9
AVL9 homolog (S. cerevisiase)
chr1_-_31505144 9.38 ENSDART00000087115
rims1b
regulating synaptic membrane exocytosis 1b
chr4_-_23839789 9.33 ENSDART00000143571
usp6nl
USP6 N-terminal like
chr15_+_29393519 9.32 ENSDART00000193488
ENSDART00000112375
gdpd5b
glycerophosphodiester phosphodiesterase domain containing 5b
chr22_+_465269 9.29 ENSDART00000145767
celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr14_-_26177156 9.29 ENSDART00000014149
fat2
FAT atypical cadherin 2
chr7_+_50053339 9.24 ENSDART00000174308
LRRC4C (1 of many)
si:dkey-6l15.1
chr15_+_1397811 9.16 ENSDART00000102125
schip1
schwannomin interacting protein 1
chr10_-_35542071 9.07 ENSDART00000162139
si:ch211-244c8.4
si:ch211-244c8.4
chr13_-_43599898 8.94 ENSDART00000084416
ENSDART00000145705
ablim1a
actin binding LIM protein 1a
chr16_-_42390441 8.92 ENSDART00000148475
cspg5a
chondroitin sulfate proteoglycan 5a
chr19_-_31802296 8.90 ENSDART00000103640
hey1
hes-related family bHLH transcription factor with YRPW motif 1
chr20_-_30035326 8.88 ENSDART00000141068
sox11b
SRY (sex determining region Y)-box 11b
chr4_+_19534833 8.86 ENSDART00000140028
lrrc4.1
leucine rich repeat containing 4.1
chr6_-_37622576 8.86 ENSDART00000154363
chst7
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
chr15_-_33925851 8.81 ENSDART00000187807
ENSDART00000187780
mag
myelin associated glycoprotein
chr13_-_22907260 8.79 ENSDART00000143097
rufy2
RUN and FYVE domain containing 2
chr11_-_36020005 8.78 ENSDART00000031993
itpr1b
inositol 1,4,5-trisphosphate receptor, type 1b
chr14_+_5117072 8.72 ENSDART00000189628
nanos1
nanos homolog 1
chr3_-_21118969 8.70 ENSDART00000129016
maza
MYC-associated zinc finger protein a (purine-binding transcription factor)
chr12_+_42436328 8.67 ENSDART00000167324
ebf3a
early B cell factor 3a
chr13_-_24218795 8.66 ENSDART00000136217
galnt2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2
chr24_+_31277360 8.59 ENSDART00000165993
f3a
coagulation factor IIIa
chr22_+_12361489 8.58 ENSDART00000182483
r3hdm1
R3H domain containing 1
chr19_+_1097393 8.54 ENSDART00000168218
CABZ01111953.1

chr2_+_24177190 8.53 ENSDART00000099546
map4l
microtubule associated protein 4 like
chr2_-_11912347 8.50 ENSDART00000023851
abhd3
abhydrolase domain containing 3
chr12_-_4651988 8.50 ENSDART00000182836
si:ch211-255p10.4
si:ch211-255p10.4
chr20_-_53366137 8.48 ENSDART00000146001
wasf1
WAS protein family, member 1
chr4_-_890220 8.42 ENSDART00000022668
aim1b
crystallin beta-gamma domain containing 1b
chr19_+_42716542 8.42 ENSDART00000144557
clasp2
cytoplasmic linker associated protein 2
chr3_-_5964557 8.41 ENSDART00000184738
BX284638.1

chr6_-_31348999 8.39 ENSDART00000153734
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr7_+_38762043 8.39 ENSDART00000036461
arhgap1
Rho GTPase activating protein 1
chr17_-_33289304 8.37 ENSDART00000135118
ENSDART00000040346
efr3ba
EFR3 homolog Ba (S. cerevisiae)
chr15_-_44601331 8.28 ENSDART00000161514
zgc:165508
zgc:165508
chr5_-_38506981 8.24 ENSDART00000097822
atp1b2b
ATPase Na+/K+ transporting subunit beta 2b
chr2_+_26656283 8.24 ENSDART00000133202
ENSDART00000099208
asph
aspartate beta-hydroxylase
chr12_+_31729075 8.22 ENSDART00000152973
RNF157
si:dkey-49c17.3
chr5_-_46273938 8.19 ENSDART00000080033
si:ch211-130m23.3
si:ch211-130m23.3
chr16_-_6821927 8.19 ENSDART00000149070
ENSDART00000149570
mbpb
myelin basic protein b
chr3_+_32425202 8.17 ENSDART00000156464
prr12b
proline rich 12b
chr10_-_27046639 8.13 ENSDART00000041841
cnih2
cornichon family AMPA receptor auxiliary protein 2
chr9_-_54840124 8.12 ENSDART00000137214
ENSDART00000085693
gpm6bb
glycoprotein M6Bb
chr9_-_10145795 8.10 ENSDART00000004745
ENSDART00000143295
hnmt
histamine N-methyltransferase
chr10_-_1718395 8.09 ENSDART00000137620
si:ch73-46j18.5
si:ch73-46j18.5
chr20_+_37844035 7.97 ENSDART00000041397
flvcr1
feline leukemia virus subgroup C cellular receptor 1
chr16_-_42390640 7.92 ENSDART00000193214
ENSDART00000102305
cspg5a
chondroitin sulfate proteoglycan 5a
chr6_-_14139503 7.85 ENSDART00000089577
cacnb4b
calcium channel, voltage-dependent, beta 4b subunit
chr2_+_25658112 7.80 ENSDART00000051234
tnika
TRAF2 and NCK interacting kinase a
chr14_+_1111332 7.79 ENSDART00000162660
si:ch1073-303k11.2
si:ch1073-303k11.2
chr25_+_35375848 7.79 ENSDART00000155721
ano3
anoctamin 3
chr7_+_48460239 7.76 ENSDART00000052113
lingo1b
leucine rich repeat and Ig domain containing 1b
chr24_-_20599781 7.75 ENSDART00000179664
ENSDART00000141823
zbtb47b
zinc finger and BTB domain containing 47b
chr24_+_39158283 7.61 ENSDART00000053139
atp6v0cb
ATPase H+ transporting V0 subunit cb
chr3_+_51684963 7.60 ENSDART00000091180
ENSDART00000183711
ENSDART00000159493
baiap2a
BAI1-associated protein 2a
chr14_-_52552875 7.57 ENSDART00000170107
ppp2r2ba
protein phosphatase 2, regulatory subunit B, beta a
chr23_+_6232895 7.56 ENSDART00000139795
syt2a
synaptotagmin IIa
chr2_+_25657958 7.55 ENSDART00000161407
tnika
TRAF2 and NCK interacting kinase a
chr6_-_35738836 7.54 ENSDART00000111642
brinp3a.1
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr3_-_36440705 7.53 ENSDART00000162875
rogdi
rogdi homolog (Drosophila)
chr2_-_52550135 7.50 ENSDART00000044411
gna11b
guanine nucleotide binding protein (G protein), alpha 11b (Gq class)
chr1_-_55873178 7.49 ENSDART00000019936
prkacab
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b
chr2_+_24867534 7.48 ENSDART00000158050
rab3aa
RAB3A, member RAS oncogene family, a
chr5_+_13427826 7.47 ENSDART00000083359
sec14l8
SEC14-like lipid binding 8
chr3_-_6767440 7.46 ENSDART00000156174
mast1b
microtubule associated serine/threonine kinase 1b
chr10_-_36592486 7.44 ENSDART00000131693
slc1a3b
solute carrier family 1 (glial high affinity glutamate transporter), member 3b
chr7_+_38717624 7.41 ENSDART00000132522
syt13
synaptotagmin XIII
chr22_-_20309283 7.37 ENSDART00000182125
ENSDART00000048775
si:dkey-110c1.10
si:dkey-110c1.10
chr2_+_26303627 7.32 ENSDART00000040278
efna2a
ephrin-A2a
chr12_-_35505610 7.31 ENSDART00000105518
camk2g1
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr12_+_9761685 7.30 ENSDART00000189522
ppp1r9bb
protein phosphatase 1, regulatory subunit 9Bb
chr14_+_33458294 7.27 ENSDART00000075278
atp1b4
ATPase Na+/K+ transporting subunit beta 4
chr15_+_40188076 7.20 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr23_+_2825940 7.18 ENSDART00000135781
plcg1
phospholipase C, gamma 1
chr18_-_50766660 7.12 ENSDART00000170663
ENSDART00000168601
zgc:158464
zgc:158464
chr10_-_15405564 7.08 ENSDART00000020665
sgtb
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr8_+_20157798 7.05 ENSDART00000124809
acsbg2
acyl-CoA synthetase bubblegum family member 2
chr24_-_18467064 7.05 ENSDART00000081946
zgc:112332
zgc:112332
chr5_+_38263240 7.04 ENSDART00000051231
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr16_+_32559821 7.03 ENSDART00000093250
pou3f2b
POU class 3 homeobox 2b
chr12_+_32159272 7.03 ENSDART00000153167
hlfb
hepatic leukemia factor b
chr14_+_31865099 6.96 ENSDART00000189124
tm9sf5
transmembrane 9 superfamily protein member 5
chr6_+_59967994 6.96 ENSDART00000050457
zgc:65895
zgc:65895
chr9_+_6082793 6.93 ENSDART00000192045
st6gal2a
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2a
chr4_-_789645 6.92 ENSDART00000164441
mapre3b
microtubule-associated protein, RP/EB family, member 3b
chr17_-_31058900 6.91 ENSDART00000134998
ENSDART00000104307
ENSDART00000172721
eml1
echinoderm microtubule associated protein like 1
chr16_-_45058919 6.90 ENSDART00000177134
gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr18_+_36625490 6.89 ENSDART00000148032
clasrp
CLK4-associating serine/arginine rich protein
chr8_+_16025554 6.86 ENSDART00000110171
elavl4
ELAV like neuron-specific RNA binding protein 4
chr14_+_22172047 6.84 ENSDART00000114750
ENSDART00000148259
gabrb2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr2_-_18830722 6.77 ENSDART00000165330
ENSDART00000165698
pbx1a
pre-B-cell leukemia homeobox 1a
chr2_-_39759059 6.77 ENSDART00000007333
slc25a36a
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36a
chr6_-_58828398 6.69 ENSDART00000090634
kif5ab
kinesin family member 5A, b
chr1_-_38709551 6.68 ENSDART00000128794
gpm6ab
glycoprotein M6Ab
chr6_-_15604417 6.65 ENSDART00000157817
lrrfip1b
leucine rich repeat (in FLII) interacting protein 1b
chr6_-_15604157 6.59 ENSDART00000141597
lrrfip1b
leucine rich repeat (in FLII) interacting protein 1b
chr15_+_5901970 6.54 ENSDART00000114134
wrb
tryptophan rich basic protein
chr3_+_46459540 6.53 ENSDART00000188150
si:ch211-66e2.5
si:ch211-66e2.5

Network of associatons between targets according to the STRING database.

First level regulatory network of sp1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 19.0 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
6.0 29.8 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
3.7 14.8 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
3.6 25.1 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
3.4 20.6 GO:0035332 positive regulation of hippo signaling(GO:0035332)
3.4 10.1 GO:0060945 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
2.9 11.6 GO:1900120 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
2.9 8.6 GO:0051580 regulation of neurotransmitter uptake(GO:0051580)
2.8 14.1 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
2.7 8.1 GO:0001692 histamine metabolic process(GO:0001692)
2.5 15.2 GO:1902269 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
2.5 7.5 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
2.5 12.3 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
2.5 54.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
2.4 7.2 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
2.4 7.1 GO:1903332 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
2.3 6.8 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
2.2 11.1 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
2.1 6.4 GO:0046677 response to antibiotic(GO:0046677)
2.1 12.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
2.0 8.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
2.0 8.0 GO:0097037 heme export(GO:0097037)
1.9 5.6 GO:0045724 positive regulation of cilium assembly(GO:0045724)
1.8 9.1 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
1.8 5.4 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
1.7 14.0 GO:0050714 positive regulation of protein secretion(GO:0050714)
1.7 8.5 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
1.7 32.2 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
1.7 8.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
1.6 4.9 GO:0014014 negative regulation of gliogenesis(GO:0014014)
1.6 9.6 GO:0008206 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
1.6 4.8 GO:2000434 regulation of protein neddylation(GO:2000434)
1.6 15.8 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
1.5 4.6 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
1.5 15.4 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
1.5 4.6 GO:0060623 regulation of chromosome condensation(GO:0060623)
1.5 6.1 GO:0055091 phospholipid homeostasis(GO:0055091)
1.5 4.5 GO:0072156 distal tubule morphogenesis(GO:0072156)
1.5 14.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
1.4 5.7 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
1.4 4.2 GO:0098725 somatic stem cell population maintenance(GO:0035019) symmetric cell division(GO:0098725)
1.4 5.6 GO:0021557 oculomotor nerve development(GO:0021557)
1.3 13.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
1.3 5.3 GO:0034969 histone arginine methylation(GO:0034969)
1.3 3.9 GO:0039529 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
1.3 5.2 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
1.3 32.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
1.3 3.8 GO:0046069 cGMP catabolic process(GO:0046069)
1.3 7.5 GO:0007603 phototransduction, visible light(GO:0007603)
1.2 6.0 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
1.2 5.9 GO:0034505 tooth mineralization(GO:0034505)
1.2 3.5 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
1.2 8.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
1.1 11.5 GO:0036368 cone photoresponse recovery(GO:0036368)
1.1 3.4 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
1.1 3.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
1.1 5.4 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
1.1 3.2 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
1.0 6.3 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
1.0 9.4 GO:1902868 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
1.0 5.2 GO:0045056 transcytosis(GO:0045056)
1.0 3.0 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.0 6.9 GO:0046600 negative regulation of centriole replication(GO:0046600)
1.0 5.8 GO:0003272 endocardial cushion formation(GO:0003272)
1.0 2.9 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.9 7.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.9 4.5 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.9 8.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.9 14.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.9 2.6 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.8 4.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.8 11.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.8 14.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.8 38.4 GO:0007019 microtubule depolymerization(GO:0007019)
0.8 7.8 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.8 6.9 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.8 7.5 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.7 2.2 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.7 3.0 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.7 8.7 GO:0021754 facial nucleus development(GO:0021754)
0.7 5.8 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.7 6.3 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.7 25.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.7 3.4 GO:0040033 miRNA metabolic process(GO:0010586) miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.7 8.7 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.7 3.3 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.7 2.6 GO:0015677 copper ion import(GO:0015677)
0.6 4.5 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.6 1.3 GO:0021742 abducens nucleus development(GO:0021742)
0.6 8.8 GO:0030316 osteoclast differentiation(GO:0030316)
0.6 5.0 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.6 6.9 GO:0046548 retinal rod cell development(GO:0046548)
0.6 3.7 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.6 3.7 GO:0080009 mRNA methylation(GO:0080009)
0.6 3.7 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.6 7.3 GO:0035094 response to nicotine(GO:0035094)
0.6 2.4 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.6 4.2 GO:0021885 forebrain cell migration(GO:0021885)
0.6 4.8 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.6 3.5 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.6 1.7 GO:0055071 manganese ion homeostasis(GO:0055071)
0.6 3.5 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.6 1.7 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.6 2.3 GO:0071869 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.6 21.7 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.6 2.3 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.6 3.4 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.6 2.3 GO:0051012 microtubule sliding(GO:0051012)
0.6 11.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.5 2.2 GO:0090299 regulation of neural crest formation(GO:0090299)
0.5 2.7 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.5 9.6 GO:0010737 protein kinase A signaling(GO:0010737)
0.5 1.6 GO:0070417 cellular response to cold(GO:0070417)
0.5 3.7 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.5 15.4 GO:0048263 determination of dorsal identity(GO:0048263)
0.5 3.7 GO:0070207 protein homotrimerization(GO:0070207)
0.5 5.8 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.5 6.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.5 10.4 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.5 5.2 GO:0007398 ectoderm development(GO:0007398)
0.5 8.7 GO:0008354 germ cell migration(GO:0008354)
0.5 4.6 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.5 15.6 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.5 2.5 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.5 5.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.5 4.5 GO:0033273 response to vitamin(GO:0033273)
0.5 3.0 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618) regulation of DNA-templated transcription in response to stress(GO:0043620)
0.5 9.4 GO:0009649 entrainment of circadian clock(GO:0009649)
0.5 2.4 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.5 2.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.5 3.9 GO:0046850 regulation of bone remodeling(GO:0046850)
0.5 4.8 GO:0072576 liver morphogenesis(GO:0072576)
0.5 1.9 GO:0019075 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.5 14.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.5 2.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.5 7.9 GO:0006265 DNA topological change(GO:0006265)
0.5 0.9 GO:0060876 semicircular canal formation(GO:0060876)
0.4 0.9 GO:0014909 smooth muscle cell migration(GO:0014909)
0.4 1.3 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.4 4.9 GO:0006007 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.4 4.4 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.4 2.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.4 1.3 GO:0001120 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.4 2.6 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.4 8.4 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.4 7.9 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.4 10.7 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.4 2.0 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.4 3.6 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.4 8.4 GO:0007020 microtubule nucleation(GO:0007020) exit from mitosis(GO:0010458) microtubule anchoring(GO:0034453)
0.4 2.4 GO:0070828 heterochromatin organization(GO:0070828)
0.4 4.3 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.4 7.1 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.4 5.8 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.4 2.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.4 0.8 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.4 2.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.4 2.6 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.4 4.1 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4 14.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.4 1.8 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.4 2.2 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.4 1.4 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.3 6.6 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.3 12.4 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.3 5.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.3 2.1 GO:0003232 bulbus arteriosus development(GO:0003232)
0.3 4.4 GO:0019233 sensory perception of pain(GO:0019233)
0.3 0.7 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.3 1.3 GO:0018199 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.3 1.0 GO:0070640 calcitriol biosynthetic process from calciol(GO:0036378) vitamin D metabolic process(GO:0042359) vitamin D biosynthetic process(GO:0042368) cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108) vitamin D3 metabolic process(GO:0070640)
0.3 5.2 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.3 4.9 GO:0015693 magnesium ion transport(GO:0015693)
0.3 1.0 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.3 4.2 GO:0010996 response to auditory stimulus(GO:0010996)
0.3 4.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.3 4.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.3 5.8 GO:0039014 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.3 2.2 GO:0036268 swimming(GO:0036268)
0.3 4.7 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.3 2.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.3 7.4 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.3 2.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.3 0.9 GO:0001207 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.3 1.8 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.3 1.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.3 0.9 GO:0061032 visceral serous pericardium development(GO:0061032)
0.3 11.4 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.3 5.1 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.3 5.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.3 1.4 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.3 28.2 GO:0008360 regulation of cell shape(GO:0008360)
0.3 8.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.3 5.0 GO:1903321 negative regulation of protein ubiquitination(GO:0031397) negative regulation of protein modification by small protein conjugation or removal(GO:1903321)
0.3 1.9 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.3 9.8 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.3 2.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.3 3.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.3 2.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.3 0.8 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.3 2.9 GO:0044458 motile cilium assembly(GO:0044458)
0.3 5.0 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.3 4.2 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.3 7.4 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.3 0.8 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 1.3 GO:0046456 icosanoid biosynthetic process(GO:0046456) fatty acid derivative biosynthetic process(GO:1901570)
0.3 6.1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.2 1.7 GO:0043931 ossification involved in bone maturation(GO:0043931) bone maturation(GO:0070977)
0.2 3.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.2 3.4 GO:0032264 IMP salvage(GO:0032264)
0.2 10.7 GO:0048278 vesicle docking(GO:0048278)
0.2 2.9 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.2 0.7 GO:1903358 regulation of Golgi organization(GO:1903358)
0.2 7.3 GO:0060536 cartilage morphogenesis(GO:0060536)
0.2 2.4 GO:0042044 fluid transport(GO:0042044)
0.2 4.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 5.3 GO:0050708 regulation of protein secretion(GO:0050708)
0.2 3.9 GO:0021884 forebrain neuron development(GO:0021884)
0.2 2.0 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.2 1.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.2 2.2 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.2 7.1 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.2 1.1 GO:0090527 actin filament reorganization(GO:0090527)
0.2 0.7 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.2 5.8 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.2 19.4 GO:0042552 myelination(GO:0042552)
0.2 5.9 GO:0072114 pronephros morphogenesis(GO:0072114)
0.2 15.0 GO:0019722 calcium-mediated signaling(GO:0019722)
0.2 10.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.2 1.3 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.2 2.9 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.2 9.0 GO:0001885 endothelial cell development(GO:0001885)
0.2 1.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.2 4.9 GO:0021854 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.2 4.0 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 3.4 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.2 8.4 GO:0003401 axis elongation(GO:0003401)
0.2 2.2 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.2 5.2 GO:0070831 basement membrane assembly(GO:0070831)
0.2 1.4 GO:0006681 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374) glycosylceramide catabolic process(GO:0046477)
0.2 3.1 GO:0048382 mesendoderm development(GO:0048382)
0.2 1.6 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.2 2.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 16.0 GO:0031101 fin regeneration(GO:0031101)
0.2 9.5 GO:0007269 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.2 3.0 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 0.9 GO:0000012 single strand break repair(GO:0000012)
0.2 0.9 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 2.0 GO:0006611 protein export from nucleus(GO:0006611)
0.2 1.8 GO:0002138 retinoic acid biosynthetic process(GO:0002138)
0.2 5.6 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.2 2.8 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 4.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2 0.3 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.2 8.5 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.2 2.8 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.2 1.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 2.2 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.2 0.6 GO:0018343 protein farnesylation(GO:0018343)
0.2 0.9 GO:0006788 heme oxidation(GO:0006788)
0.2 1.8 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.2 10.6 GO:0003407 neural retina development(GO:0003407)
0.2 0.6 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.1 1.2 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 3.4 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.1 1.8 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 1.0 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.6 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.1 31.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.7 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 14.3 GO:0006821 chloride transport(GO:0006821)
0.1 4.8 GO:0001764 neuron migration(GO:0001764)
0.1 1.7 GO:0050890 cognition(GO:0050890)
0.1 16.2 GO:0050770 regulation of axonogenesis(GO:0050770)
0.1 1.0 GO:0001966 thigmotaxis(GO:0001966)
0.1 1.3 GO:0010138 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.1 2.9 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.1 1.1 GO:0090398 cellular senescence(GO:0090398)
0.1 1.3 GO:0006188 IMP biosynthetic process(GO:0006188)
0.1 2.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 1.4 GO:0060324 face development(GO:0060324)
0.1 0.5 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 7.9 GO:0051017 actin filament bundle assembly(GO:0051017)
0.1 2.9 GO:0015833 peptide transport(GO:0015833)
0.1 12.8 GO:0006338 chromatin remodeling(GO:0006338)
0.1 4.3 GO:0001841 neural tube formation(GO:0001841)
0.1 6.2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 5.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.7 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 12.8 GO:0060026 convergent extension(GO:0060026)
0.1 37.4 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.1 5.6 GO:0034968 histone lysine methylation(GO:0034968)
0.1 7.6 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 1.1 GO:0009303 rRNA transcription(GO:0009303)
0.1 2.7 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 0.7 GO:0032218 riboflavin transport(GO:0032218)
0.1 9.2 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.1 0.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 1.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 2.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 4.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.4 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.1 3.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.7 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 0.3 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 0.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 2.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.3 GO:1900182 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 0.4 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1 3.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 3.4 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 1.1 GO:0050684 regulation of mRNA processing(GO:0050684)
0.1 11.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 10.0 GO:0006909 phagocytosis(GO:0006909)
0.1 5.6 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.1 6.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 0.6 GO:0061316 canonical Wnt signaling pathway involved in heart development(GO:0061316) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 0.3 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 3.6 GO:0000077 DNA damage checkpoint(GO:0000077)
0.1 0.6 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 1.6 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.1 0.5 GO:1902742 apoptotic process involved in morphogenesis(GO:0060561) apoptotic process involved in development(GO:1902742)
0.1 2.3 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 1.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 1.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 1.4 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.1 18.7 GO:0008380 RNA splicing(GO:0008380)
0.1 1.3 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 3.7 GO:0060215 primitive hemopoiesis(GO:0060215)
0.1 0.6 GO:0090329 regulation of DNA-dependent DNA replication(GO:0090329)
0.1 0.1 GO:2000252 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.1 10.4 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.1 0.5 GO:1990709 presynaptic active zone organization(GO:1990709)
0.1 2.5 GO:0032456 endocytic recycling(GO:0032456)
0.1 1.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 0.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.5 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.1 11.1 GO:0006813 potassium ion transport(GO:0006813)
0.1 1.2 GO:0015671 oxygen transport(GO:0015671)
0.1 2.6 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 1.7 GO:0003341 cilium movement(GO:0003341)
0.1 1.0 GO:0060972 left/right pattern formation(GO:0060972)
0.1 0.5 GO:0042476 odontogenesis(GO:0042476)
0.1 5.8 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.4 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 3.0 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 1.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 4.1 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.9 GO:0044782 cilium organization(GO:0044782)
0.0 0.7 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 14.7 GO:0031175 neuron projection development(GO:0031175)
0.0 0.2 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.3 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.1 GO:0002369 T cell cytokine production(GO:0002369)
0.0 10.0 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.4 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 3.0 GO:0030509 BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0 0.3 GO:0097324 melanocyte migration(GO:0097324)
0.0 1.1 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 1.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.5 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 1.6 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.5 GO:0007041 lysosomal transport(GO:0007041)
0.0 2.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.6 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 6.4 GO:0098916 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916)
0.0 1.2 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.5 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 22.2 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 0.2 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.0 GO:0072017 distal tubule development(GO:0072017)
0.0 0.3 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 0.2 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.5 GO:0031076 embryonic camera-type eye development(GO:0031076)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 23.7 GO:0070062 extracellular exosome(GO:0070062)
3.9 39.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
2.4 41.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
2.4 7.1 GO:0072380 TRC complex(GO:0072380)
2.2 2.2 GO:0071564 npBAF complex(GO:0071564)
1.9 7.5 GO:0043291 RAVE complex(GO:0043291)
1.9 11.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
1.8 51.6 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
1.6 29.4 GO:0043209 myelin sheath(GO:0043209)
1.5 7.6 GO:0042584 chromaffin granule membrane(GO:0042584)
1.3 9.4 GO:0016234 inclusion body(GO:0016234)
1.2 29.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
1.0 7.3 GO:0043194 axon initial segment(GO:0043194)
1.0 12.5 GO:0044295 axonal growth cone(GO:0044295)
1.0 4.0 GO:0060171 stereocilium membrane(GO:0060171)
0.9 3.7 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.9 4.6 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.9 4.5 GO:0008091 spectrin(GO:0008091)
0.8 9.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.8 5.6 GO:0001650 fibrillar center(GO:0001650)
0.8 3.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.7 2.8 GO:0032584 growth cone membrane(GO:0032584)
0.7 2.0 GO:0032301 MutSalpha complex(GO:0032301)
0.7 10.0 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.7 4.6 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.6 2.4 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.6 22.7 GO:0043679 axon terminus(GO:0043679)
0.6 16.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.6 2.3 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.6 87.2 GO:0008021 synaptic vesicle(GO:0008021)
0.5 9.9 GO:0005801 cis-Golgi network(GO:0005801)
0.5 13.6 GO:0071565 nBAF complex(GO:0071565)
0.5 7.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.5 9.6 GO:0030667 secretory granule membrane(GO:0030667)
0.5 19.5 GO:0030426 growth cone(GO:0030426)
0.5 3.0 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.5 19.5 GO:0014069 postsynaptic density(GO:0014069)
0.5 15.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.5 6.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.4 4.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.4 6.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.4 5.6 GO:0031594 neuromuscular junction(GO:0031594)
0.4 35.0 GO:0005871 kinesin complex(GO:0005871)
0.4 5.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.4 36.6 GO:0043025 neuronal cell body(GO:0043025)
0.4 28.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.4 11.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 2.8 GO:0000812 Swr1 complex(GO:0000812)
0.4 12.6 GO:0030175 filopodium(GO:0030175)
0.3 4.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 20.7 GO:0031225 anchored component of membrane(GO:0031225)
0.3 2.9 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.3 3.1 GO:0036449 microtubule minus-end(GO:0036449)
0.3 6.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 0.9 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.3 1.2 GO:0097255 R2TP complex(GO:0097255)
0.3 5.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 2.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 1.3 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.3 12.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 4.2 GO:0000813 ESCRT I complex(GO:0000813)
0.2 6.7 GO:0060293 germ plasm(GO:0060293)
0.2 13.8 GO:0072686 mitotic spindle(GO:0072686)
0.2 2.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 5.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 2.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.7 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.2 5.2 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 11.0 GO:0008305 integrin complex(GO:0008305)
0.2 3.7 GO:0031209 SCAR complex(GO:0031209)
0.2 1.8 GO:0032019 mitochondrial cloud(GO:0032019)
0.2 0.9 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.2 139.0 GO:0043005 neuron projection(GO:0043005)
0.2 2.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 0.7 GO:0070578 RISC-loading complex(GO:0070578)
0.2 2.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 9.6 GO:0031201 SNARE complex(GO:0031201)
0.2 12.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 3.5 GO:0015030 Cajal body(GO:0015030)
0.2 3.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 2.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 14.0 GO:0055037 recycling endosome(GO:0055037)
0.2 1.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 3.0 GO:0090544 BAF-type complex(GO:0090544)
0.2 9.5 GO:0000922 spindle pole(GO:0000922)
0.2 1.9 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.1 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.2 0.6 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 5.7 GO:0030863 cortical cytoskeleton(GO:0030863)
0.1 2.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 5.7 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 0.6 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 1.9 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.1 2.6 GO:0032039 integrator complex(GO:0032039)
0.1 1.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 2.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 2.1 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 2.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.6 GO:0032587 ruffle membrane(GO:0032587)
0.1 2.7 GO:0098978 glutamatergic synapse(GO:0098978)
0.1 5.2 GO:0016592 mediator complex(GO:0016592)
0.1 10.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 5.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 11.4 GO:0005770 late endosome(GO:0005770)
0.1 18.9 GO:0045202 synapse(GO:0045202)
0.1 1.5 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 3.6 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 6.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 6.4 GO:0005802 trans-Golgi network(GO:0005802)
0.1 1.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.5 GO:0071818 BAT3 complex(GO:0071818)
0.1 3.5 GO:0030286 dynein complex(GO:0030286)
0.1 1.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 2.3 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 2.5 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.5 GO:0000145 exocyst(GO:0000145)
0.1 1.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 3.3 GO:0009986 cell surface(GO:0009986)
0.1 5.6 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 0.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 3.4 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 11.2 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.5 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 1.2 GO:0035869 ciliary transition zone(GO:0035869)
0.0 2.9 GO:0016607 nuclear speck(GO:0016607)
0.0 4.1 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 3.2 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 77.2 GO:0005886 plasma membrane(GO:0005886)
0.0 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 2.4 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.6 GO:0005911 cell-cell junction(GO:0005911)
0.0 1.6 GO:0005764 lysosome(GO:0005764)
0.0 0.8 GO:0036064 ciliary basal body(GO:0036064)
0.0 2.7 GO:0005815 microtubule organizing center(GO:0005815)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 12.1 GO:1903136 cuprous ion binding(GO:1903136)
3.9 11.6 GO:0031701 angiotensin receptor binding(GO:0031701)
3.5 14.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
3.5 6.9 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
3.2 9.7 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
3.0 9.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
2.8 8.5 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
2.8 17.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
2.5 15.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
2.5 5.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
2.3 6.8 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
2.2 8.9 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
2.1 32.2 GO:0005504 fatty acid binding(GO:0005504)
2.0 41.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
1.9 7.7 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
1.9 9.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
1.9 13.0 GO:0030274 LIM domain binding(GO:0030274)
1.6 32.2 GO:0001671 ATPase activator activity(GO:0001671)
1.5 4.6 GO:0046978 TAP1 binding(GO:0046978)
1.5 17.9 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
1.4 34.7 GO:0030371 translation repressor activity(GO:0030371)
1.4 4.2 GO:0008022 protein C-terminus binding(GO:0008022)
1.4 5.4 GO:0071889 14-3-3 protein binding(GO:0071889)
1.1 4.6 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
1.1 4.4 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
1.0 59.5 GO:0044325 ion channel binding(GO:0044325)
1.0 3.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
1.0 8.0 GO:0015232 heme transporter activity(GO:0015232)
1.0 22.2 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.9 7.6 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.9 5.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.9 5.6 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.9 2.8 GO:0043621 protein self-association(GO:0043621)
0.9 3.6 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.9 29.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.9 21.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.9 6.9 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.8 16.1 GO:0008242 omega peptidase activity(GO:0008242)
0.8 10.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.8 2.5 GO:0031835 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.8 2.4 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.8 6.5 GO:0016801 hydrolase activity, acting on ether bonds(GO:0016801)
0.8 9.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.8 38.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.8 4.5 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.7 3.7 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.7 3.7 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.7 7.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.7 2.0 GO:0032405 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.7 2.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.7 5.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.7 2.6 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.7 7.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.6 10.4 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.6 1.9 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.6 13.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.6 2.5 GO:0042054 histone methyltransferase activity(GO:0042054)
0.6 2.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.6 7.9 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.6 5.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.6 41.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.6 5.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.6 1.7 GO:0052855 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.6 9.6 GO:0045159 myosin II binding(GO:0045159)
0.6 5.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.6 8.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.6 11.7 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.5 3.3 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.5 4.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.5 4.4 GO:0004985 opioid receptor activity(GO:0004985)
0.5 2.6 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.5 4.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.5 10.4 GO:0097602 cullin family protein binding(GO:0097602)
0.5 2.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.5 6.1 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.5 17.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.5 8.8 GO:0033691 sialic acid binding(GO:0033691)
0.5 3.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.5 2.4 GO:0060182 apelin receptor activity(GO:0060182)
0.5 13.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.5 7.0 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.5 4.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.5 13.4 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.5 12.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.4 3.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.4 4.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.4 3.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.4 5.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.4 10.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.4 11.4 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.4 1.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.4 7.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.4 2.1 GO:0035173 histone kinase activity(GO:0035173)
0.4 3.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.4 20.3 GO:0008013 beta-catenin binding(GO:0008013)
0.4 4.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.4 12.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.4 2.0 GO:0034046 poly(G) binding(GO:0034046)
0.4 22.2 GO:0017124 SH3 domain binding(GO:0017124)
0.4 2.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.4 3.0 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.4 49.9 GO:0005516 calmodulin binding(GO:0005516)
0.4 3.7 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.4 2.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.4 12.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.3 4.5 GO:0016405 CoA-ligase activity(GO:0016405)
0.3 3.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.3 1.3 GO:0008905 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.3 3.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 2.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 1.3 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.3 1.0 GO:0031073 vitamin D3 25-hydroxylase activity(GO:0030343) cholesterol 26-hydroxylase activity(GO:0031073)
0.3 1.3 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.3 5.5 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.3 15.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 2.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.3 3.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 2.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.3 7.6 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.3 4.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 3.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.3 4.7 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.3 1.7 GO:0030331 estrogen receptor binding(GO:0030331) retinoic acid receptor binding(GO:0042974)
0.3 3.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.3 1.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 1.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.3 5.2 GO:0015026 coreceptor activity(GO:0015026)
0.3 4.9 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.3 7.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.3 1.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.3 4.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.3 2.9 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.3 1.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.3 1.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.3 0.8 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 5.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 11.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 3.0 GO:0042285 xylosyltransferase activity(GO:0042285)
0.2 3.9 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.2 6.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 2.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 1.8 GO:0016530 metallochaperone activity(GO:0016530)
0.2 3.5 GO:0002039 p53 binding(GO:0002039)
0.2 3.9 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.2 6.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 9.4 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.2 2.9 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.2 6.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.6 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.2 11.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 1.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 1.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 2.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 1.6 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 5.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 1.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 9.5 GO:0031491 nucleosome binding(GO:0031491)
0.2 2.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.2 2.3 GO:0034595 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.2 4.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 9.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 4.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 0.5 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 1.2 GO:0098809 nitrite reductase activity(GO:0098809)
0.2 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.2 1.5 GO:0032977 membrane insertase activity(GO:0032977)
0.2 0.7 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.2 1.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 4.3 GO:0019902 phosphatase binding(GO:0019902)
0.2 0.6 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 0.9 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 51.7 GO:0015631 tubulin binding(GO:0015631)
0.2 22.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 2.9 GO:0070411 I-SMAD binding(GO:0070411)
0.1 55.0 GO:0003924 GTPase activity(GO:0003924)
0.1 5.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 6.7 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 10.9 GO:0030276 clathrin binding(GO:0030276)
0.1 0.6 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.1 6.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 2.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 15.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 6.3 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 3.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 2.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 3.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 1.3 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.7 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 10.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 1.4 GO:0005537 mannose binding(GO:0005537)
0.1 3.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.1 GO:0030552 cAMP binding(GO:0030552)
0.1 0.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.3 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 1.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.4 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 9.5 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 9.2 GO:0043492 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.1 30.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 0.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 2.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.8 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 25.3 GO:0005096 GTPase activator activity(GO:0005096)
0.1 1.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 2.2 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 3.8 GO:0071949 FAD binding(GO:0071949)
0.1 1.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 13.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 1.4 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 62.0 GO:0005509 calcium ion binding(GO:0005509)
0.1 11.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 2.5 GO:0005548 phospholipid transporter activity(GO:0005548)
0.1 14.9 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.1 1.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 6.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 2.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.9 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 2.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.4 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 1.1 GO:0098632 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 5.1 GO:0000287 magnesium ion binding(GO:0000287)
0.0 1.9 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 1.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 1.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.5 GO:0032451 demethylase activity(GO:0032451)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0099604 ligand-gated calcium channel activity(GO:0099604)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0017069 snRNA binding(GO:0017069)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 20.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
1.1 5.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.9 18.8 PID REELIN PATHWAY Reelin signaling pathway
0.9 9.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.8 16.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.7 5.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.6 9.6 ST ADRENERGIC Adrenergic Pathway
0.6 20.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.6 19.3 SIG CHEMOTAXIS Genes related to chemotaxis
0.5 19.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.5 3.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.5 6.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.4 10.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.4 9.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.4 6.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.3 3.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3 5.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.3 6.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.3 9.7 PID AURORA B PATHWAY Aurora B signaling
0.3 9.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 5.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 2.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 4.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 5.7 PID ATM PATHWAY ATM pathway
0.2 3.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 3.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 1.7 ST GA12 PATHWAY G alpha 12 Pathway
0.2 2.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 3.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 2.9 PID ARF 3PATHWAY Arf1 pathway
0.2 1.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 4.3 PID BCR 5PATHWAY BCR signaling pathway
0.2 4.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 5.5 PID NOTCH PATHWAY Notch signaling pathway
0.2 2.6 ST GA13 PATHWAY G alpha 13 Pathway
0.2 5.2 PID BMP PATHWAY BMP receptor signaling
0.1 6.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 3.9 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 4.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 1.2 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 2.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 1.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 0.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.9 PID P73PATHWAY p73 transcription factor network
0.0 0.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 48.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
1.8 9.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.8 7.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
1.8 29.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
1.4 16.9 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
1.3 10.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
1.2 15.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
1.0 4.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.9 8.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.8 7.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.7 4.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.7 4.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.6 3.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.6 10.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.5 4.9 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.5 6.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.5 5.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.4 6.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.4 6.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.4 8.0 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.4 4.0 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.4 3.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.4 5.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.4 8.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.4 3.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.4 7.2 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.4 10.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.4 3.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3 4.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 1.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 2.9 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.3 2.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.3 6.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3 3.9 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.3 4.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.3 2.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.3 2.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.3 1.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 2.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 2.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 4.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 13.5 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.2 2.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 3.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 8.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 6.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 2.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 3.5 REACTOME KINESINS Genes involved in Kinesins
0.2 1.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 5.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 9.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 3.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 4.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 14.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 2.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 9.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 1.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.7 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 0.9 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 2.4 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.1 5.3 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.1 1.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 2.5 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 1.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 0.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 3.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor