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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for sp2

Z-value: 1.24

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Transcription factors associated with sp2

Gene Symbol Gene ID Gene Info
sp2
ENSDARG00000076763 sp2 transcription factor
sp2
ENSDARG00000113443 sp2 transcription factor
sp2
ENSDARG00000115477 sp2 transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sp2dr11_v1_chr11_-_12008001_120080010.422.2e-05Click!

Activity profile of sp2 motif

Sorted Z-values of sp2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_39219537 23.17 ENSDART00000005764
cyp39a1
cytochrome P450, family 39, subfamily A, polypeptide 1
chr10_+_1849874 11.50 ENSDART00000158897
ENSDART00000149956
apc
adenomatous polyposis coli
chr3_-_36440705 10.92 ENSDART00000162875
rogdi
rogdi homolog (Drosophila)
chr2_-_11912347 10.89 ENSDART00000023851
abhd3
abhydrolase domain containing 3
chr6_-_13408680 10.76 ENSDART00000151566
fmnl2b
formin-like 2b
chr2_+_24868010 10.63 ENSDART00000078838
rab3aa
RAB3A, member RAS oncogene family, a
chr23_+_44732863 10.51 ENSDART00000160044
ENSDART00000172268
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr19_-_15855427 10.43 ENSDART00000133059
cited4a
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a
chr8_-_4618653 9.63 ENSDART00000025535
sept5a
septin 5a
chr8_+_23165749 9.60 ENSDART00000063057
dnajc5aa
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr4_+_19534833 8.97 ENSDART00000140028
lrrc4.1
leucine rich repeat containing 4.1
chr10_+_15777258 8.19 ENSDART00000140511
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr8_+_36803415 7.88 ENSDART00000111680
iqsec2b
IQ motif and Sec7 domain 2b
chr3_+_51684963 7.87 ENSDART00000091180
ENSDART00000183711
ENSDART00000159493
baiap2a
BAI1-associated protein 2a
chr22_+_465269 7.81 ENSDART00000145767
celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr16_-_36798783 7.75 ENSDART00000145697
calb1
calbindin 1
chr1_-_56176976 7.56 ENSDART00000052688
c3a.1
complement component c3a, duplicate 1
chr13_+_1100197 7.36 ENSDART00000139560
ppp3r1a
protein phosphatase 3, regulatory subunit B, alpha a
chr11_-_32723851 7.32 ENSDART00000155592
pcdh17
protocadherin 17
chr10_+_21650828 7.29 ENSDART00000160754
pcdh1g1
protocadherin 1 gamma 1
chr10_+_15777064 7.21 ENSDART00000114483
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr2_+_24867534 7.09 ENSDART00000158050
rab3aa
RAB3A, member RAS oncogene family, a
chr10_+_10788811 7.04 ENSDART00000101077
ENSDART00000139143
ptgdsa
prostaglandin D2 synthase a
chr11_-_97817 6.85 ENSDART00000092903
elmo2
engulfment and cell motility 2
chr10_+_44924684 6.81 ENSDART00000181360
ENSDART00000170418
ENSDART00000170327
sec14l7
SEC14-like lipid binding 7
chr7_-_52876683 6.66 ENSDART00000172910
map1aa
microtubule-associated protein 1Aa
chr21_+_43253538 6.66 ENSDART00000179940
ENSDART00000164806
ENSDART00000147026
shroom1
shroom family member 1
chr2_+_25657958 6.60 ENSDART00000161407
tnika
TRAF2 and NCK interacting kinase a
chr1_-_22861348 6.54 ENSDART00000139412
SMIM18
si:dkey-92j12.6
chr2_+_25658112 6.47 ENSDART00000051234
tnika
TRAF2 and NCK interacting kinase a
chr19_+_4912817 6.45 ENSDART00000101658
ENSDART00000165082
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr20_+_37844035 6.31 ENSDART00000041397
flvcr1
feline leukemia virus subgroup C cellular receptor 1
chr6_-_58828398 6.27 ENSDART00000090634
kif5ab
kinesin family member 5A, b
chr7_+_48460239 6.25 ENSDART00000052113
lingo1b
leucine rich repeat and Ig domain containing 1b
chr24_-_20599781 6.24 ENSDART00000179664
ENSDART00000141823
zbtb47b
zinc finger and BTB domain containing 47b
chr22_+_12366516 6.09 ENSDART00000157802
r3hdm1
R3H domain containing 1
chr14_-_46113321 6.08 ENSDART00000169040
ENSDART00000161475
ENSDART00000124925
si:ch211-235e9.8
si:ch211-235e9.8
chr5_-_38506981 6.01 ENSDART00000097822
atp1b2b
ATPase Na+/K+ transporting subunit beta 2b
chr6_-_58828113 5.92 ENSDART00000180934
kif5ab
kinesin family member 5A, b
chr20_-_34868814 5.90 ENSDART00000153049
stmn4
stathmin-like 4
chr21_+_21279159 5.86 ENSDART00000148346
itpkca
inositol-trisphosphate 3-kinase Ca
chr2_+_59015878 5.84 ENSDART00000148816
ENSDART00000122795
si:ch1073-391i24.1
si:ch1073-391i24.1
chr24_+_41931585 5.76 ENSDART00000130310
epb41l3a
erythrocyte membrane protein band 4.1-like 3a
chr12_+_19036380 5.70 ENSDART00000153086
ENSDART00000181060
kctd17
potassium channel tetramerization domain containing 17
chr19_+_1097393 5.63 ENSDART00000168218
CABZ01111953.1

chr14_-_32503363 5.57 ENSDART00000034883
mcf2a
MCF.2 cell line derived transforming sequence a
chr23_-_13875252 5.55 ENSDART00000104834
ENSDART00000193807
g6pd
glucose-6-phosphate dehydrogenase
chr17_+_27723490 5.49 ENSDART00000123588
ENSDART00000170462
ENSDART00000169708
qkia
QKI, KH domain containing, RNA binding a
chr18_-_3166726 5.41 ENSDART00000165002
aqp11
aquaporin 11
chr16_-_52733384 5.37 ENSDART00000147236
ENSDART00000056101
azin1a
antizyme inhibitor 1a
chr1_-_10647307 5.20 ENSDART00000103548
si:dkey-31e10.1
si:dkey-31e10.1
chr13_+_16521898 5.14 ENSDART00000122557
kcnma1a
potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr9_+_13714379 5.10 ENSDART00000017593
ENSDART00000145503
tmem237a
transmembrane protein 237a
chr18_+_21122818 4.98 ENSDART00000060015
ENSDART00000060184
chka
choline kinase alpha
chr20_-_16156419 4.97 ENSDART00000037420
ralgps2
Ral GEF with PH domain and SH3 binding motif 2
chr1_-_10647484 4.94 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
si:dkey-31e10.1
chr15_-_47956388 4.87 ENSDART00000116506
si:ch1073-111c8.3
si:ch1073-111c8.3
chr21_+_5589923 4.82 ENSDART00000160885
stbd1
starch binding domain 1
chr18_+_27077853 4.78 ENSDART00000125326
ENSDART00000192660
ENSDART00000098334
ppp1r15b
protein phosphatase 1, regulatory subunit 15B
chr3_+_14388010 4.71 ENSDART00000171726
ENSDART00000165452
tmem56b
transmembrane protein 56b
chr13_+_23677949 4.70 ENSDART00000144215
pcnxl2
pecanex-like 2 (Drosophila)
chr3_-_50998577 4.59 ENSDART00000157735
cdc42ep4a
CDC42 effector protein (Rho GTPase binding) 4a
chr12_-_33893381 4.47 ENSDART00000153280
sema4gb
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Gb
chr9_-_8454060 4.41 ENSDART00000110158
irs2b
insulin receptor substrate 2b
chr16_-_7793457 4.41 ENSDART00000113483
trim71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr14_+_33264303 4.27 ENSDART00000130680
ENSDART00000075187
pdzd11
PDZ domain containing 11
chr14_+_24283915 4.27 ENSDART00000172868
klhl3
kelch-like family member 3
chr1_-_55196103 4.17 ENSDART00000140153
mri1
methylthioribose-1-phosphate isomerase 1
chr15_-_20731297 4.03 ENSDART00000114464
tpst1
tyrosylprotein sulfotransferase 1
chr1_+_39553040 4.00 ENSDART00000137676
tenm3
teneurin transmembrane protein 3
chr6_-_35738836 3.99 ENSDART00000111642
brinp3a.1
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr15_-_6976851 3.96 ENSDART00000158474
ENSDART00000168943
ENSDART00000169944
si:ch73-311h14.2
si:ch73-311h14.2
chr12_-_37449396 3.95 ENSDART00000152951
cdc42ep4b
CDC42 effector protein (Rho GTPase binding) 4b
chr10_-_641609 3.84 ENSDART00000041236
rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr1_+_9004719 3.84 ENSDART00000006211
ENSDART00000137211
prkcba
protein kinase C, beta a
chr18_-_127873 3.80 ENSDART00000148490
trpm7
transient receptor potential cation channel, subfamily M, member 7
chr2_-_44282796 3.69 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
mpz
myelin protein zero
chr12_-_14211293 3.69 ENSDART00000158399
avl9
AVL9 homolog (S. cerevisiase)
chr19_-_26769867 3.67 ENSDART00000043776
ENSDART00000159489
ENSDART00000138675
prrc2a
proline-rich coiled-coil 2A
chr9_+_42095220 3.63 ENSDART00000148317
ENSDART00000134431
pcbp3
poly(rC) binding protein 3
chr3_-_16039619 3.62 ENSDART00000143324
spsb3a
splA/ryanodine receptor domain and SOCS box containing 3a
chr3_+_14499075 3.53 ENSDART00000162853
ENSDART00000167776
ENSDART00000162932
ENSDART00000168229
tmem205
transmembrane protein 205
chr14_-_45394704 3.45 ENSDART00000173078
ENSDART00000125970
si:ch211-168f7.5
si:ch211-168f7.5
chr18_-_14836600 3.43 ENSDART00000045232
mtss1la
metastasis suppressor 1-like a
chr2_+_37480669 3.38 ENSDART00000029801
sppl2
signal peptide peptidase-like 2
chr24_-_28381404 3.29 ENSDART00000148406
prkag2a
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr3_+_62126981 3.28 ENSDART00000060527
drc3
dynein regulatory complex subunit 3
chr22_-_6651382 3.27 ENSDART00000124308
si:ch211-209l18.4
si:ch211-209l18.4
chr19_-_26770083 3.26 ENSDART00000193811
ENSDART00000174455
prrc2a
proline-rich coiled-coil 2A
chr3_+_35611625 3.21 ENSDART00000190995
traf7
TNF receptor-associated factor 7
chr17_+_53292215 3.19 ENSDART00000170686
si:ch1073-416d2.3
si:ch1073-416d2.3
chr9_-_38156894 3.15 ENSDART00000134759
si:dkey-219c10.4
si:dkey-219c10.4
chr24_-_10828560 3.15 ENSDART00000132282
fam49bb
family with sequence similarity 49, member Bb
chr5_+_26075230 3.15 ENSDART00000098473
klf9
Kruppel-like factor 9
chr4_-_23839789 3.14 ENSDART00000143571
usp6nl
USP6 N-terminal like
chr3_+_11548516 3.12 ENSDART00000059117
mmd
monocyte to macrophage differentiation-associated
chr18_-_14836862 3.11 ENSDART00000124843
mtss1la
metastasis suppressor 1-like a
chr15_-_9421481 3.10 ENSDART00000189045
ENSDART00000177158
sacs
sacsin molecular chaperone
chr19_+_13994563 3.05 ENSDART00000164696
tmem222b
transmembrane protein 222b
chr24_-_30096666 3.02 ENSDART00000183285
plppr4b
phospholipid phosphatase related 4b
chr11_-_41130239 3.02 ENSDART00000173268
dnajc11b
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr4_-_22519516 3.01 ENSDART00000130409
ENSDART00000186258
ENSDART00000002851
ENSDART00000123801
kdm7aa
lysine (K)-specific demethylase 7Aa
chr23_+_2825940 3.01 ENSDART00000135781
plcg1
phospholipase C, gamma 1
chr17_+_51764310 3.00 ENSDART00000157171
si:ch211-168d23.3
si:ch211-168d23.3
chr15_+_33966739 2.96 ENSDART00000160614
tmem106ba
transmembrane protein 106Ba
chr6_+_2271559 2.95 ENSDART00000165223
pbx1b
pre-B-cell leukemia homeobox 1b
chr11_-_44030962 2.92 ENSDART00000171910
FP016005.1

chr8_-_41279326 2.90 ENSDART00000075491
pop5
POP5 homolog, ribonuclease P/MRP subunit
chr10_+_39200213 2.86 ENSDART00000153727
ei24
etoposide induced 2.4
chr10_-_43721530 2.85 ENSDART00000025366
cetn3
centrin 3
chr13_-_638485 2.84 ENSDART00000066080
ENSDART00000128969
slit1a
slit homolog 1a (Drosophila)
chr6_-_18400548 2.82 ENSDART00000179797
ENSDART00000164891
trim25
tripartite motif containing 25
chr10_-_22831611 2.82 ENSDART00000160115
per1a
period circadian clock 1a
chr15_+_29393519 2.75 ENSDART00000193488
ENSDART00000112375
gdpd5b
glycerophosphodiester phosphodiesterase domain containing 5b
chr10_+_39199547 2.75 ENSDART00000075943
ei24
etoposide induced 2.4
chr17_-_43287290 2.75 ENSDART00000156885
EML5
si:dkey-1f12.3
chr20_+_36623807 2.74 ENSDART00000149171
ENSDART00000062895
srp9
signal recognition particle 9
chr21_-_40557281 2.74 ENSDART00000172327
taok1b
TAO kinase 1b
chr8_+_39802506 2.66 ENSDART00000018862
hnf1a
HNF1 homeobox a
chr5_-_12743196 2.56 ENSDART00000188976
ENSDART00000137705
lztr1
leucine-zipper-like transcription regulator 1
chr18_+_36625490 2.56 ENSDART00000148032
clasrp
CLK4-associating serine/arginine rich protein
chr15_+_25489406 2.55 ENSDART00000162482
zgc:152863
zgc:152863
chr14_+_31865324 2.54 ENSDART00000039880
tm9sf5
transmembrane 9 superfamily protein member 5
chr15_-_25209308 2.50 ENSDART00000157857
mnta
MAX network transcriptional repressor a
chr2_-_23004286 2.47 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
znf414
mllt1b
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr11_+_19370717 2.46 ENSDART00000165906
prickle2b
prickle homolog 2b
chr20_-_14781904 2.44 ENSDART00000187200
ENSDART00000179912
ENSDART00000160481
ENSDART00000026969
suco
SUN domain containing ossification factor
chr9_-_24413008 2.41 ENSDART00000135897
tmeff2a
transmembrane protein with EGF-like and two follistatin-like domains 2a
chr3_-_16227683 2.41 ENSDART00000111707
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr10_-_44924289 2.41 ENSDART00000171267
tuba7l
tubulin, alpha 7 like
chr16_-_17586883 2.40 ENSDART00000017142
m6pr
mannose-6-phosphate receptor (cation dependent)
chr23_-_18982499 2.36 ENSDART00000012507
bcl2l1
bcl2-like 1
chr18_-_22094102 2.35 ENSDART00000100904
pard6a
par-6 family cell polarity regulator alpha
chr9_-_53899106 2.33 ENSDART00000171986
cog3
component of oligomeric golgi complex 3
chr18_+_50907675 2.33 ENSDART00000159950
si:ch1073-450f2.1
si:ch1073-450f2.1
chr3_-_62380146 2.32 ENSDART00000155853
gprc5ba
G protein-coupled receptor, class C, group 5, member Ba
chr7_-_69636502 2.26 ENSDART00000126739
tspan5a
tetraspanin 5a
chr22_-_7563593 2.25 ENSDART00000106062
BX511034.1

chr2_+_44666705 2.22 ENSDART00000139137
yeats2
YEATS domain containing 2
chr10_+_37500234 2.22 ENSDART00000132096
ENSDART00000099473
msi2a
musashi RNA-binding protein 2a
chr17_-_40956035 2.21 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr19_+_26340736 2.20 ENSDART00000013497
mylipa
myosin regulatory light chain interacting protein a
chr7_+_38962459 2.18 ENSDART00000173851
dgkza
diacylglycerol kinase, zeta a
chr19_+_42983613 2.18 ENSDART00000033724
fabp3
fatty acid binding protein 3, muscle and heart
chr2_+_38881165 2.16 ENSDART00000141850
carmil3
capping protein regulator and myosin 1 linker 3
chr23_-_30960506 2.15 ENSDART00000142661
osbpl2a
oxysterol binding protein-like 2a
chr3_-_32541033 2.15 ENSDART00000151476
ENSDART00000055324
rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr20_+_36820965 2.11 ENSDART00000153085
ENSDART00000062935
heca
hdc homolog, cell cycle regulator
chr18_+_507618 2.11 ENSDART00000159464
nedd4a
neural precursor cell expressed, developmentally down-regulated 4a
chr3_-_7170661 2.10 ENSDART00000190345
BX005085.4

chr5_-_14326959 2.09 ENSDART00000137355
tet3
tet methylcytosine dioxygenase 3
chr20_+_46741074 2.08 ENSDART00000145294
si:ch211-57i17.1
si:ch211-57i17.1
chr12_-_17492852 2.07 ENSDART00000012421
ENSDART00000138766
ENSDART00000130735
minpp1b
multiple inositol-polyphosphate phosphatase 1b
chr1_+_54677173 2.05 ENSDART00000114705
gprc5bb
G protein-coupled receptor, class C, group 5, member Bb
chr15_+_3125136 2.02 ENSDART00000130968
rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr8_-_5847533 2.01 ENSDART00000192489
CABZ01102147.1

chr18_-_40684756 1.99 ENSDART00000113799
ENSDART00000139042
si:ch211-132b12.7
si:ch211-132b12.7
chr13_-_42724645 1.99 ENSDART00000046066
capn1a
calpain 1, (mu/I) large subunit a
chr7_+_38249858 1.97 ENSDART00000150158
si:dkey-78a14.4
si:dkey-78a14.4
chr5_+_36899691 1.97 ENSDART00000132322
hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr3_+_22578369 1.96 ENSDART00000187695
ENSDART00000182678
ENSDART00000112270
tanc2a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2a
chr15_-_47857687 1.93 ENSDART00000098982
ENSDART00000151594
h3f3b.1
H3 histone, family 3B.1
chr15_-_20731638 1.90 ENSDART00000170616
tpst1
tyrosylprotein sulfotransferase 1
chr7_-_6592142 1.87 ENSDART00000160137
kcnj10a
potassium inwardly-rectifying channel, subfamily J, member 10a
chr7_-_48396193 1.82 ENSDART00000083555
sin3ab
SIN3 transcription regulator family member Ab
chr17_+_44756247 1.80 ENSDART00000153773
cipca
CLOCK-interacting pacemaker a
chr23_+_30898013 1.79 ENSDART00000146859
cables2a
Cdk5 and Abl enzyme substrate 2a
chr1_+_44838706 1.77 ENSDART00000162779
ENSDART00000147357
kdm2aa
lysine (K)-specific demethylase 2Aa
chr21_-_13972745 1.77 ENSDART00000143874
akna
AT-hook transcription factor
chr18_-_46882649 1.76 ENSDART00000192056
gramd1bb
GRAM domain containing 1Bb
chr5_+_51443009 1.75 ENSDART00000083350
rasgrf2b
Ras protein-specific guanine nucleotide-releasing factor 2b
chr17_+_11507131 1.75 ENSDART00000013170
kif26ba
kinesin family member 26Ba
chr16_+_4839078 1.74 ENSDART00000150111
ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr9_+_21146862 1.71 ENSDART00000136365
hao2
hydroxyacid oxidase 2 (long chain)
chr14_+_31865099 1.70 ENSDART00000189124
tm9sf5
transmembrane 9 superfamily protein member 5
chr4_-_5795309 1.70 ENSDART00000039987
pgm3
phosphoglucomutase 3
chr9_+_23825440 1.69 ENSDART00000138470
ints6
integrator complex subunit 6
chr20_-_51727860 1.69 ENSDART00000147044
brox
BRO1 domain and CAAX motif containing
chr11_-_36341189 1.67 ENSDART00000159752
sort1a
sortilin 1a
chr15_+_20543770 1.63 ENSDART00000092357
sgsm2
small G protein signaling modulator 2
chr20_-_28931901 1.61 ENSDART00000153082
ENSDART00000046042
susd6
sushi domain containing 6
chr11_-_1967438 1.60 ENSDART00000155844
nr1d4b
nuclear receptor subfamily 1, group D, member 4b
chr7_-_45852270 1.58 ENSDART00000170224
shcbp1
SHC SH2-domain binding protein 1
chr23_+_41200854 1.56 ENSDART00000109567
nhsa
Nance-Horan syndrome a (congenital cataracts and dental anomalies)
chr21_-_11054876 1.55 ENSDART00000146576
nedd4l
neural precursor cell expressed, developmentally down-regulated 4-like
chr3_-_33941875 1.55 ENSDART00000047660
gtf2f1
general transcription factor IIF, polypeptide 1
chr5_-_30080332 1.53 ENSDART00000140049
bco2a
beta-carotene oxygenase 2a
chr15_-_25435085 1.52 ENSDART00000112079
tlcd2
TLC domain containing 2
chr13_+_3819475 1.52 ENSDART00000139958
qkib
QKI, KH domain containing, RNA binding b
chr24_-_26622423 1.50 ENSDART00000182044
tnikb
TRAF2 and NCK interacting kinase b
chr1_+_54115839 1.48 ENSDART00000180214
LO017722.2

chr14_+_12109535 1.48 ENSDART00000054620
ENSDART00000121913
kctd12b
potassium channel tetramerisation domain containing 12b
chr18_-_35842554 1.46 ENSDART00000088488
opa3
optic atrophy 3
chr3_-_33941319 1.45 ENSDART00000026090
ENSDART00000111878
gtf2f1
general transcription factor IIF, polypeptide 1
chr11_-_36341028 1.45 ENSDART00000146093
sort1a
sortilin 1a
chr9_-_202805 1.44 ENSDART00000182260
CABZ01067557.1

chr15_+_24388782 1.39 ENSDART00000191661
ENSDART00000179995
ENSDART00000111226
sez6b
seizure related 6 homolog b
chr19_+_12406583 1.37 ENSDART00000013865
ENSDART00000151535
seh1l
SEH1-like (S. cerevisiae)
chr14_+_36869273 1.35 ENSDART00000111674
F2RL3
si:ch211-132p1.2
chr11_-_35975026 1.33 ENSDART00000186219
itpr1b
inositol 1,4,5-trisphosphate receptor, type 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of sp2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 17.7 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
3.9 23.2 GO:0006699 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
2.9 11.5 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
2.2 10.9 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
1.9 7.8 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
1.9 5.7 GO:0045724 positive regulation of cilium assembly(GO:0045724)
1.8 5.3 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
1.7 12.2 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
1.6 6.3 GO:0097037 heme export(GO:0097037)
1.4 4.3 GO:0072156 distal tubule morphogenesis(GO:0072156)
1.1 3.2 GO:0046069 cGMP catabolic process(GO:0046069)
1.0 3.0 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
1.0 4.0 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.9 3.8 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.9 2.8 GO:0039535 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.9 5.4 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.9 4.4 GO:0010586 miRNA metabolic process(GO:0010586)
0.9 7.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.9 16.5 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.9 4.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.9 8.5 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.7 5.9 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.7 5.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.7 3.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.7 2.0 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.7 7.8 GO:0021754 facial nucleus development(GO:0021754)
0.6 3.5 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.5 3.1 GO:0003272 endocardial cushion formation(GO:0003272)
0.5 3.0 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.5 4.5 GO:1904861 excitatory synapse assembly(GO:1904861)
0.4 2.1 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.4 4.0 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.4 4.8 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.4 5.1 GO:0010996 response to auditory stimulus(GO:0010996)
0.4 3.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.4 1.5 GO:0055091 phospholipid homeostasis(GO:0055091)
0.4 1.1 GO:0090184 regulation of neurotransmitter uptake(GO:0051580) regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.3 1.0 GO:0046677 response to antibiotic(GO:0046677)
0.3 1.0 GO:0006565 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
0.3 6.5 GO:0097178 ruffle assembly(GO:0097178)
0.3 2.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.3 5.9 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.3 4.7 GO:0008089 anterograde axonal transport(GO:0008089)
0.3 6.7 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.3 2.4 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.3 1.9 GO:0036268 swimming(GO:0036268)
0.2 2.0 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.2 2.4 GO:0046850 regulation of bone remodeling(GO:0046850)
0.2 3.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 2.4 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 1.3 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.2 3.8 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.2 9.2 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 4.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.2 21.6 GO:0008360 regulation of cell shape(GO:0008360)
0.2 1.4 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.2 2.8 GO:0042542 response to hydrogen peroxide(GO:0042542)
0.2 7.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.2 0.7 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.2 2.4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 2.7 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.1 1.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 2.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 1.8 GO:0007530 sex determination(GO:0007530)
0.1 1.0 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.5 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 4.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.8 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 1.3 GO:0071715 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.1 0.5 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.1 4.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 3.2 GO:1903039 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 2.7 GO:0097194 execution phase of apoptosis(GO:0097194)
0.1 2.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 2.7 GO:0030073 insulin secretion(GO:0030073)
0.1 0.5 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
0.1 2.4 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.3 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 7.8 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.1 1.7 GO:0035329 hippo signaling(GO:0035329)
0.1 0.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 2.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.8 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 6.2 GO:0042552 myelination(GO:0042552)
0.1 3.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 1.7 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 2.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 5.7 GO:0006956 complement activation(GO:0006956)
0.1 0.2 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.1 0.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.7 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 1.8 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 3.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 2.4 GO:0001841 neural tube formation(GO:0001841)
0.0 5.1 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 2.6 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.2 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 3.0 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.2 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 1.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.0 GO:0090148 membrane fission(GO:0090148)
0.0 5.0 GO:0046578 regulation of Ras protein signal transduction(GO:0046578)
0.0 1.0 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 2.2 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 2.2 GO:0006909 phagocytosis(GO:0006909)
0.0 5.6 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 3.8 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 7.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 3.7 GO:0016236 macroautophagy(GO:0016236)
0.0 0.3 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.7 GO:2000779 regulation of double-strand break repair(GO:2000779)
0.0 0.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 13.1 GO:0007268 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916)
0.0 0.2 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.6 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 1.6 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 1.5 GO:0019216 regulation of lipid metabolic process(GO:0019216)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.6 GO:0003401 axis elongation(GO:0003401)
0.0 1.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 1.6 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 1.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.9 GO:0043291 RAVE complex(GO:0043291)
1.7 16.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
1.6 11.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.8 3.4 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.7 4.4 GO:0070062 extracellular exosome(GO:0070062)
0.7 2.9 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.4 3.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.4 2.7 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.3 10.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 7.8 GO:0043195 terminal bouton(GO:0043195)
0.3 4.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 3.0 GO:0061617 MICOS complex(GO:0061617)
0.3 3.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 4.7 GO:0043209 myelin sheath(GO:0043209)
0.3 9.6 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.2 0.7 GO:1990879 CST complex(GO:1990879)
0.2 2.6 GO:0016580 Sin3 complex(GO:0016580)
0.2 2.3 GO:0017119 Golgi transport complex(GO:0017119)
0.1 6.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 5.1 GO:0035869 ciliary transition zone(GO:0035869)
0.1 12.0 GO:0005871 kinesin complex(GO:0005871)
0.1 7.9 GO:0030175 filopodium(GO:0030175)
0.1 0.5 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 14.1 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 1.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 9.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 2.4 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 17.0 GO:0008021 synaptic vesicle(GO:0008021)
0.1 10.7 GO:0043025 neuronal cell body(GO:0043025)
0.1 6.2 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 3.0 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 1.7 GO:0032039 integrator complex(GO:0032039)
0.1 0.6 GO:0016272 prefoldin complex(GO:0016272)
0.1 2.2 GO:0005844 polysome(GO:0005844)
0.1 1.3 GO:0030667 secretory granule membrane(GO:0030667)
0.1 3.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 3.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 4.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 27.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 6.2 GO:0030424 axon(GO:0030424)
0.0 0.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.3 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.5 GO:0042383 sarcolemma(GO:0042383)
0.0 1.0 GO:0005795 Golgi stack(GO:0005795)
0.0 1.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.4 GO:0098791 trans-Golgi network(GO:0005802) Golgi subcompartment(GO:0098791)
0.0 2.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 1.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.0 GO:0045211 postsynaptic membrane(GO:0045211)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.9 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
2.6 7.8 GO:0005499 vitamin D binding(GO:0005499)
1.9 5.6 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
1.4 4.3 GO:0008022 protein C-terminus binding(GO:0008022)
1.0 4.8 GO:2001070 starch binding(GO:2001070)
0.9 5.4 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.8 16.5 GO:0001671 ATPase activator activity(GO:0001671)
0.8 6.3 GO:0015232 heme transporter activity(GO:0015232)
0.8 3.0 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.8 3.0 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.7 5.9 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.7 2.9 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.6 15.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.5 7.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.5 2.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.4 4.4 GO:0035198 miRNA binding(GO:0035198)
0.4 3.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.4 2.7 GO:0008312 7S RNA binding(GO:0008312)
0.4 5.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.4 1.1 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.4 4.4 GO:0005158 insulin receptor binding(GO:0005158)
0.4 5.9 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.4 2.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.3 2.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.3 1.0 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.3 10.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 5.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.3 2.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.3 5.7 GO:0097602 cullin family protein binding(GO:0097602)
0.3 21.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.3 2.4 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.3 6.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 2.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.2 4.9 GO:0030371 translation repressor activity(GO:0030371)
0.2 3.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2 1.1 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.2 3.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 0.8 GO:0030626 U12 snRNA binding(GO:0030626)
0.2 2.4 GO:0005537 mannose binding(GO:0005537)
0.2 8.7 GO:0008013 beta-catenin binding(GO:0008013)
0.2 2.4 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.2 2.8 GO:0048495 Roundabout binding(GO:0048495)
0.2 0.7 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.2 9.8 GO:0017124 SH3 domain binding(GO:0017124)
0.2 0.8 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.2 0.5 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.1 5.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 3.8 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 1.7 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 3.3 GO:0016208 AMP binding(GO:0016208)
0.1 3.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 1.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.1 2.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 3.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 1.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 4.4 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 2.2 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.7 GO:0010181 FMN binding(GO:0010181)
0.1 4.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 2.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 26.2 GO:0003924 GTPase activity(GO:0003924)
0.1 0.7 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 8.1 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 1.0 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 1.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 8.3 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 1.9 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 16.6 GO:0015631 tubulin binding(GO:0015631)
0.0 1.8 GO:0032452 histone demethylase activity(GO:0032452)
0.0 2.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 4.0 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 9.4 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 3.2 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.4 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 2.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0019213 deacetylase activity(GO:0019213)
0.0 4.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 8.5 GO:0003779 actin binding(GO:0003779)
0.0 1.8 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.0 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.3 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 11.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.3 2.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 3.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 6.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 1.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.4 PID RHOA PATHWAY RhoA signaling pathway
0.1 2.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 23.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.8 11.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.8 3.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.5 6.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.5 2.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 5.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.4 6.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.3 2.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.2 5.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 3.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.2 2.8 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.2 1.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 2.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 2.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 0.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.4 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 3.8 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 2.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions