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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for spi1a+spi1b

Z-value: 4.34

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Transcription factors associated with spi1a+spi1b

Gene Symbol Gene ID Gene Info
spi1b
ENSDARG00000000767 Spi-1 proto-oncogene b
spi1a
ENSDARG00000067797 Spi-1 proto-oncogene a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
spi1adr11_v1_chr25_+_35553542_355535420.787.8e-21Click!
spi1bdr11_v1_chr7_-_32659048_326590480.755.8e-18Click!

Activity profile of spi1a+spi1b motif

Sorted Z-values of spi1a+spi1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_43872889 40.25 ENSDART00000170553
mslna
mesothelin a
chr6_-_8489810 38.27 ENSDART00000124643
rasal3
RAS protein activator like 3
chr15_+_20239141 37.98 ENSDART00000101152
ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr21_+_25765734 36.97 ENSDART00000021664
cldnb
claudin b
chr7_-_34265481 34.45 ENSDART00000173596
si:ch211-98n17.5
si:ch211-98n17.5
chr15_+_12435975 34.27 ENSDART00000168011
tmprss4a
transmembrane protease, serine 4a
chr3_-_32859335 33.00 ENSDART00000158916
si:dkey-16l2.20
si:dkey-16l2.20
chr6_-_49063085 31.84 ENSDART00000156124
si:ch211-105j21.9
si:ch211-105j21.9
chr7_+_49664174 31.49 ENSDART00000137059
ENSDART00000131210
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr23_-_10177442 30.33 ENSDART00000144280
ENSDART00000129044
krt5
keratin 5
chr15_-_29598679 29.92 ENSDART00000155153
si:ch211-207n23.2
si:ch211-207n23.2
chr16_+_17715243 29.33 ENSDART00000149437
ENSDART00000149596
si:dkey-87o1.2
si:dkey-87o1.2
chr13_+_8840772 28.31 ENSDART00000059321
epcam
epithelial cell adhesion molecule
chr10_+_4987766 27.71 ENSDART00000121959
si:ch73-234b20.5
si:ch73-234b20.5
chr10_+_13209580 27.59 ENSDART00000000887
ENSDART00000136932
rassf6
Ras association (RalGDS/AF-6) domain family 6
chr13_-_50108337 27.53 ENSDART00000133308
nid1a
nidogen 1a
chr22_+_5478353 27.42 ENSDART00000160596
tppp
tubulin polymerization promoting protein
chr19_-_40198478 26.95 ENSDART00000191736
grn2
granulin 2
chr23_+_26142613 26.82 ENSDART00000165046
ptpn22
protein tyrosine phosphatase, non-receptor type 22
chr20_+_38285671 26.72 ENSDART00000061432
ccl38a.4
chemokine (C-C motif) ligand 38, duplicate 4
chr9_+_24088062 26.41 ENSDART00000126198
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr16_+_48753664 25.87 ENSDART00000155148
si:ch73-31d8.2
si:ch73-31d8.2
chr8_+_19356072 25.54 ENSDART00000063272
mpeg1.2
macrophage expressed 1, tandem duplicate 2
chr9_-_443451 25.38 ENSDART00000165642
si:dkey-11f4.14
si:dkey-11f4.14
chr16_+_29492749 25.23 ENSDART00000179680
ctsk
cathepsin K
chr15_+_12436220 25.17 ENSDART00000169894
tmprss4a
transmembrane protease, serine 4a
chr16_-_31756859 24.95 ENSDART00000149170
ENSDART00000126617
ENSDART00000182722
ptpn6
protein tyrosine phosphatase, non-receptor type 6
chr22_-_15577060 24.93 ENSDART00000176291
hsh2d
hematopoietic SH2 domain containing
chr24_-_31306724 24.87 ENSDART00000165399
acp5b
acid phosphatase 5b, tartrate resistant
chr8_+_32406885 24.80 ENSDART00000167600
epgn
epithelial mitogen homolog (mouse)
chr5_+_37087583 24.74 ENSDART00000049900
tagln2
transgelin 2
chr23_+_26142807 24.69 ENSDART00000158878
ptpn22
protein tyrosine phosphatase, non-receptor type 22
chr15_+_46356879 24.62 ENSDART00000154388
wu:fb18f06
wu:fb18f06
chr1_-_37383539 24.56 ENSDART00000127579
scpp1
secretory calcium-binding phosphoprotein 1
chr7_-_49892991 24.55 ENSDART00000126240
cd44a
CD44 molecule (Indian blood group) a
chr7_-_2039060 24.52 ENSDART00000173879
si:cabz01007794.1
si:cabz01007794.1
chr3_-_30941362 23.27 ENSDART00000076830
coro1a
coronin, actin binding protein, 1A
chr3_+_40809011 23.09 ENSDART00000033713
arpc1b
actin related protein 2/3 complex, subunit 1B
chr7_+_34794829 22.51 ENSDART00000009698
ENSDART00000075089
ENSDART00000173456
esrp2
epithelial splicing regulatory protein 2
chr13_-_34858500 22.42 ENSDART00000184843
sptlc3
serine palmitoyltransferase, long chain base subunit 3
chr21_+_28747069 22.16 ENSDART00000014058
zgc:100829
zgc:100829
chr11_-_18384534 22.10 ENSDART00000156499
prkcdb
protein kinase C, delta b
chr7_+_19482084 22.01 ENSDART00000173873
si:ch211-212k18.7
si:ch211-212k18.7
chr20_+_10498986 21.63 ENSDART00000064114
zgc:100997
zgc:100997
chr12_-_30558694 21.62 ENSDART00000153417
si:ch211-28p3.3
si:ch211-28p3.3
chr1_-_45347393 21.17 ENSDART00000173024
si:ch211-243a20.4
si:ch211-243a20.4
chr16_-_36099492 20.86 ENSDART00000180905
CU499336.2

chr23_+_44599012 20.85 ENSDART00000125198
pfn1
profilin 1
chr14_+_29769336 20.77 ENSDART00000105898
si:dkey-34l15.1
si:dkey-34l15.1
chr1_-_45157243 20.76 ENSDART00000131882
mucms1
mucin, multiple PTS and SEA group, member 1
chr2_+_24762567 20.66 ENSDART00000078866
ifi30
interferon, gamma-inducible protein 30
chr6_+_112579 20.56 ENSDART00000034505
ap1m2
adaptor-related protein complex 1, mu 2 subunit
chr11_-_21404044 20.56 ENSDART00000080116
ikbke
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr23_+_31815423 20.50 ENSDART00000075730
ENSDART00000075726
myb
v-myb avian myeloblastosis viral oncogene homolog
chr21_+_22985078 20.42 ENSDART00000156491
lpar6b
lysophosphatidic acid receptor 6b
chr20_+_26683933 19.87 ENSDART00000139852
ENSDART00000077751
foxq1b
forkhead box Q1b
chr17_-_8886735 19.64 ENSDART00000121997
nkl.3
NK-lysin tandem duplicate 3
chr21_+_15723069 19.60 ENSDART00000149126
ENSDART00000130628
p2rx4a
purinergic receptor P2X, ligand-gated ion channel, 4a
chr3_+_29942338 19.51 ENSDART00000158220
ifi35
interferon-induced protein 35
chr9_+_30387930 19.43 ENSDART00000112827
si:dkey-18p12.4
si:dkey-18p12.4
chr3_+_18579806 19.33 ENSDART00000180967
ENSDART00000089765
arhgap17b
Rho GTPase activating protein 17b
chr17_-_2039511 19.14 ENSDART00000160223
spint1a
serine peptidase inhibitor, Kunitz type 1 a
chr16_-_41990421 19.05 ENSDART00000055921
pycard
PYD and CARD domain containing
chr7_-_26603743 18.95 ENSDART00000099003
plscr3b
phospholipid scramblase 3b
chr7_-_5316901 18.95 ENSDART00000181505
ENSDART00000124367
si:cabz01074946.1
si:cabz01074946.1
chr3_+_36275633 18.78 ENSDART00000185027
ENSDART00000149532
ENSDART00000102883
ENSDART00000148444
zgc:86896
zgc:86896
chr20_+_38276690 18.76 ENSDART00000061437
ccl38.6
chemokine (C-C motif) ligand 38, duplicate 6
chr20_-_19864131 18.75 ENSDART00000057819
ptk2bb
protein tyrosine kinase 2 beta, b
chr3_-_53508580 18.48 ENSDART00000073978
zgc:171711
zgc:171711
chr14_+_20911310 18.28 ENSDART00000160318
lygl2
lysozyme g-like 2
chr16_+_38201840 18.23 ENSDART00000044971
myo1eb
myosin IE, b
chr16_+_21789703 17.93 ENSDART00000153617
trim108
tripartite motif containing 108
chr19_-_325584 17.81 ENSDART00000134266
gpd1c
glycerol-3-phosphate dehydrogenase 1c
chr7_-_7810348 17.77 ENSDART00000171984
cxcl19
chemokine (C-X-C motif) ligand 19
chr1_+_40308077 17.52 ENSDART00000138992
vwa10.2
von Willebrand factor A domain containing 10, tandem duplicate 2
chr1_-_37383741 17.43 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
scpp1
secretory calcium-binding phosphoprotein 1
chr7_+_15736230 17.27 ENSDART00000109942
mctp2b
multiple C2 domains, transmembrane 2b
chr19_-_34927201 17.26 ENSDART00000076518
sla1
Src-like-adaptor 1
chr20_+_46040666 17.24 ENSDART00000060744
si:dkey-7c18.24
si:dkey-7c18.24
chr16_+_29492937 17.14 ENSDART00000011497
ctsk
cathepsin K
chr15_-_29598444 17.14 ENSDART00000154847
si:ch211-207n23.2
si:ch211-207n23.2
chr16_-_24832038 16.86 ENSDART00000153731
si:dkey-79d12.5
si:dkey-79d12.5
chr10_-_41980797 16.86 ENSDART00000076575
rhof
ras homolog family member F
chr3_-_27647845 16.68 ENSDART00000151625
si:ch211-157c3.4
si:ch211-157c3.4
chr4_-_992063 16.68 ENSDART00000181630
ENSDART00000183898
ENSDART00000160902
naga
N-acetylgalactosaminidase, alpha
chr21_+_28747236 16.59 ENSDART00000137874
zgc:100829
zgc:100829
chr7_+_19483277 16.56 ENSDART00000173750
si:ch211-212k18.7
si:ch211-212k18.7
chr12_+_22576404 16.52 ENSDART00000172053
capgb
capping protein (actin filament), gelsolin-like b
chr21_+_30937690 16.49 ENSDART00000022562
rhogb
ras homolog family member Gb
chr25_+_4750972 16.42 ENSDART00000168903
si:zfos-2372e4.1
si:zfos-2372e4.1
chr2_-_37744951 16.36 ENSDART00000144807
myo9b
myosin IXb
chr5_-_37959874 16.31 ENSDART00000031719
mpzl2b
myelin protein zero-like 2b
chr15_-_2652640 16.15 ENSDART00000146094
cldnf
claudin f
chr19_-_24958393 16.13 ENSDART00000098592
si:ch211-195b13.6
si:ch211-195b13.6
chr9_-_56272465 16.06 ENSDART00000039235
lcp1
lymphocyte cytosolic protein 1 (L-plastin)
chr17_-_5860222 15.99 ENSDART00000058894
si:ch73-340m8.2
si:ch73-340m8.2
chr10_+_38417512 15.95 ENSDART00000112457
samsn1b
SAM domain, SH3 domain and nuclear localisation signals 1b
chr20_+_9223514 15.91 ENSDART00000023293
kcnk5b
potassium channel, subfamily K, member 5b
chr18_+_22109379 15.90 ENSDART00000147230
zgc:158868
zgc:158868
chr3_+_29510818 15.85 ENSDART00000055407
ENSDART00000193743
ENSDART00000123619
rac2
Rac family small GTPase 2
chr15_+_36445350 15.80 ENSDART00000154552
si:dkey-262k9.2
si:dkey-262k9.2
chr3_+_24641489 15.75 ENSDART00000055590
ENSDART00000186635
zgc:113411
zgc:113411
chr24_-_31904924 15.74 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
si:ch73-78o10.1
chr3_+_2971852 15.72 ENSDART00000059271
BX004816.1

chr17_-_6508406 15.35 ENSDART00000002778
dnajc5gb
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma b
chr10_+_26612321 15.19 ENSDART00000134322
fhl1b
four and a half LIM domains 1b
chr11_+_44135351 15.18 ENSDART00000182914
FO704721.1

chr20_-_7293837 15.18 ENSDART00000100060
dsc2l
desmocollin 2 like
chr7_+_29115890 15.18 ENSDART00000052345
tradd
tnfrsf1a-associated via death domain
chr22_-_3914162 15.09 ENSDART00000187174
ENSDART00000190612
ENSDART00000187928
ENSDART00000057224
ENSDART00000184758
mhc1uma
major histocompatibility complex class I UMA
chr10_-_22127942 15.05 ENSDART00000133374
ponzr2
plac8 onzin related protein 2
chr14_-_40797117 15.03 ENSDART00000122369
elf1
E74-like ETS transcription factor 1
chr15_-_18209672 14.98 ENSDART00000141508
ENSDART00000136280
btr16
bloodthirsty-related gene family, member 16
chr9_+_41224100 14.96 ENSDART00000141792
stat1b
signal transducer and activator of transcription 1b
chr10_-_20650302 14.91 ENSDART00000142028
ENSDART00000064662
rassf2b
Ras association (RalGDS/AF-6) domain family member 2b
chr22_+_3914318 14.86 ENSDART00000188774
ENSDART00000082034
FO904903.1
Danio rerio major histocompatibility complex class I ULA (mhc1ula), mRNA.
chr10_-_7785930 14.86 ENSDART00000043961
ENSDART00000111058
mpx
myeloid-specific peroxidase
chr21_+_27448856 14.80 ENSDART00000100784
cfbl
complement factor b-like
chr5_-_69948099 14.72 ENSDART00000034639
ENSDART00000191111
ugt2a4
UDP glucuronosyltransferase 2 family, polypeptide A4
chr8_-_3312384 14.67 ENSDART00000035965
fut9b
fucosyltransferase 9b
chr15_+_5088210 14.65 ENSDART00000183423
mxf
myxovirus (influenza virus) resistance F
chr8_-_28349859 14.63 ENSDART00000062671
tuba8l
tubulin, alpha 8 like
chr5_-_25582721 14.41 ENSDART00000123986
anxa1a
annexin A1a
chr10_-_35149513 14.40 ENSDART00000063434
ENSDART00000131291
ripk4
receptor-interacting serine-threonine kinase 4
chr5_-_23909934 14.39 ENSDART00000142516
si:ch211-135f11.1
si:ch211-135f11.1
chr12_-_30540699 14.36 ENSDART00000167712
ENSDART00000102464
zgc:153920
zgc:153920
chr14_+_35428152 14.34 ENSDART00000172597
sytl4
synaptotagmin-like 4
chr7_+_39418869 14.32 ENSDART00000169195
CT030188.1

chr10_+_8875195 14.25 ENSDART00000141045
itga2.3
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 3
chr4_+_7677318 14.21 ENSDART00000149218
elk3
ELK3, ETS-domain protein
chr8_-_12867128 14.00 ENSDART00000142201
slc2a6
solute carrier family 2 (facilitated glucose transporter), member 6
chr4_-_22310956 13.90 ENSDART00000162585
hcls1
hematopoietic cell-specific Lyn substrate 1
chr2_-_6548838 13.88 ENSDART00000052419
rgs18
regulator of G protein signaling 18
chr21_-_25295087 13.85 ENSDART00000087910
ENSDART00000147860
st14b
suppression of tumorigenicity 14 (colon carcinoma) b
chr9_+_45839260 13.83 ENSDART00000114814
twist2
twist2
chr5_-_68876211 13.78 ENSDART00000097254
sftpbb
surfactant protein Bb
chr10_-_24648228 13.75 ENSDART00000081834
ENSDART00000132830
stoml3b
stomatin (EPB72)-like 3b
chr7_+_22657566 13.67 ENSDART00000141048
ponzr5
plac8 onzin related protein 5
chr6_-_40657653 13.66 ENSDART00000154359
ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr25_+_34014523 13.55 ENSDART00000182856
anxa2a
annexin A2a
chr13_-_32898962 13.49 ENSDART00000163757
rock2a
rho-associated, coiled-coil containing protein kinase 2a
chr15_+_36457888 13.48 ENSDART00000155100
si:dkey-262k9.2
si:dkey-262k9.2
chr5_-_61445697 13.44 ENSDART00000050898
ncf1
neutrophil cytosolic factor 1
chr3_+_32492467 13.42 ENSDART00000151329
trpm4a
transient receptor potential cation channel, subfamily M, member 4a
chr24_-_32582378 13.40 ENSDART00000066590
rdh12l
retinol dehydrogenase 12, like
chr19_+_40350468 13.34 ENSDART00000087444
hepacam2
HEPACAM family member 2
chr12_-_4243268 13.26 ENSDART00000131275
zgc:92313
zgc:92313
chr14_+_23709543 13.22 ENSDART00000136909
gnpda1
glucosamine-6-phosphate deaminase 1
chr1_-_25177086 13.21 ENSDART00000144711
ENSDART00000177225
tmem154
transmembrane protein 154
chr19_-_25005609 13.20 ENSDART00000151129
xkr8.2
XK, Kell blood group complex subunit-related family, member 8, tandem duplicate 2
chr22_-_15717897 13.14 ENSDART00000008424
malt2
MALT paracaspase 2
chr8_-_36469117 13.11 ENSDART00000111240
mhc2dab
major histocompatibility complex class II DAB gene
chr24_-_25096199 13.09 ENSDART00000185076
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr8_-_19975087 13.05 ENSDART00000182220
lpxn
leupaxin
chr20_-_13660600 13.01 ENSDART00000063826
TAGAP
si:ch211-122h15.4
chr22_+_5687615 12.99 ENSDART00000133241
ENSDART00000019854
ENSDART00000138102
dnase1l4.2
deoxyribonuclease 1 like 4, tandem duplicate 2
chr7_+_26029672 12.98 ENSDART00000101126
alox12
arachidonate 12-lipoxygenase
chr14_-_16807206 12.96 ENSDART00000157957
tcirg1b
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr16_+_20934353 12.93 ENSDART00000052660
skap2
src kinase associated phosphoprotein 2
chr7_+_1045637 12.90 ENSDART00000111531
epdl1
ependymin-like 1
chr21_-_40174647 12.90 ENSDART00000183738
ENSDART00000076840
ENSDART00000145109
slco2b1
solute carrier organic anion transporter family, member 2B1
chr10_-_24391716 12.88 ENSDART00000141332
ENSDART00000100772
slc43a2b
solute carrier family 43 (amino acid system L transporter), member 2b
chr2_-_55337585 12.88 ENSDART00000177924
tpm4b
tropomyosin 4b
chr3_-_40528333 12.85 ENSDART00000193047
actb2
actin, beta 2
chr9_+_23772516 12.66 ENSDART00000183126
si:ch211-219a4.3
si:ch211-219a4.3
chr1_+_54834119 12.65 ENSDART00000140020
si:ch211-196h16.4
si:ch211-196h16.4
chr19_+_43523690 12.62 ENSDART00000113031
wasf2
WAS protein family, member 2
chr7_-_60351537 12.61 ENSDART00000159875
plcb3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr10_-_28395620 12.54 ENSDART00000168907
CR392341.4

chr25_+_18475032 12.50 ENSDART00000073564
tes
testis derived transcript (3 LIM domains)
chr19_+_18758014 12.50 ENSDART00000158935
clic1
chloride intracellular channel 1
chr20_-_35470891 12.50 ENSDART00000152993
ENSDART00000016090
pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr3_-_50136424 12.48 ENSDART00000188843
btr02
bloodthirsty-related gene family, member 2
chr16_-_25233515 12.47 ENSDART00000058943
zgc:110182
zgc:110182
chr6_-_40842768 12.46 ENSDART00000076160
mustn1a
musculoskeletal, embryonic nuclear protein 1a
chr21_-_26114886 12.38 ENSDART00000139320
nipal4
NIPA-like domain containing 4
chr20_-_34127415 12.35 ENSDART00000010028
ptgs2b
prostaglandin-endoperoxide synthase 2b
chr12_-_22400999 12.31 ENSDART00000153194
si:dkey-38p12.3
si:dkey-38p12.3
chr3_+_42923275 12.29 ENSDART00000168228
tmem184a
transmembrane protein 184a
chr12_-_28983584 12.28 ENSDART00000112374
zgc:171713
zgc:171713
chr5_+_28271412 12.24 ENSDART00000031727
vamp8
vesicle-associated membrane protein 8 (endobrevin)
chr19_-_5669122 12.23 ENSDART00000112211
si:ch211-264f5.2
si:ch211-264f5.2
chr12_-_9438227 12.21 ENSDART00000003932
erbb2
erb-b2 receptor tyrosine kinase 2
chr11_+_29975830 12.20 ENSDART00000148929
si:ch73-226l13.2
si:ch73-226l13.2
chr5_+_20421539 12.19 ENSDART00000164499
selplg
selectin P ligand
chr6_-_42949184 12.19 ENSDART00000147208
edem1
ER degradation enhancer, mannosidase alpha-like 1
chr25_+_13191391 12.16 ENSDART00000109937
si:ch211-147m6.2
si:ch211-147m6.2
chr7_+_19482877 12.11 ENSDART00000077868
si:ch211-212k18.7
si:ch211-212k18.7
chr9_+_21165017 12.10 ENSDART00000145933
ENSDART00000142985
si:rp71-68n21.9
si:rp71-68n21.9
chr12_-_15205087 12.08 ENSDART00000010068
sult1st6
sulfotransferase family 1, cytosolic sulfotransferase 6
chr5_-_26879302 12.05 ENSDART00000098571
ENSDART00000139086
zgc:64051
zgc:64051
chr20_+_10498704 12.05 ENSDART00000192985
zgc:100997
zgc:100997
chr11_+_1602916 12.04 ENSDART00000184434
ENSDART00000112597
ENSDART00000192165
si:dkey-40c23.2
si:dkey-40c23.3
si:dkey-40c23.2
si:dkey-40c23.3
chr24_-_21131607 12.02 ENSDART00000010126
zdhhc23b
zinc finger, DHHC-type containing 23b
chr9_+_13120419 11.92 ENSDART00000141005
fam117bb
family with sequence similarity 117, member Bb
chr7_+_35268054 11.86 ENSDART00000113842
dpep2
dipeptidase 2
chr22_-_17688868 11.86 ENSDART00000012336
ENSDART00000147070
tjp3
tight junction protein 3
chr9_-_25993849 11.79 ENSDART00000144840
arhgap15
Rho GTPase activating protein 15
chr21_-_35534401 11.77 ENSDART00000112308
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr18_+_15937610 11.76 ENSDART00000061134
ENSDART00000154505
itpr2
inositol 1,4,5-trisphosphate receptor, type 2

Network of associatons between targets according to the STRING database.

First level regulatory network of spi1a+spi1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 21.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
7.0 21.1 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
6.9 20.7 GO:0002369 T cell cytokine production(GO:0002369)
6.4 38.4 GO:0070254 mucus secretion(GO:0070254)
6.1 18.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
5.8 17.4 GO:0034138 toll-like receptor 3 signaling pathway(GO:0034138)
5.0 14.9 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
4.9 29.3 GO:0050832 defense response to fungus(GO:0050832)
4.7 18.7 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
4.5 13.5 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) mediolateral intercalation(GO:0060031)
4.5 17.8 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
4.3 17.3 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
4.3 17.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
3.8 11.4 GO:0002855 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
3.5 14.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
3.5 20.7 GO:0048194 Golgi vesicle budding(GO:0048194)
3.4 37.9 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
3.4 20.5 GO:0030852 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
3.2 16.2 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
3.2 22.3 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
3.2 28.6 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
3.1 34.4 GO:0045453 bone resorption(GO:0045453)
3.1 15.6 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
3.1 12.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
3.1 12.2 GO:0048940 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
3.0 15.2 GO:0002159 desmosome assembly(GO:0002159)
2.9 8.7 GO:0035331 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
2.9 20.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
2.9 60.6 GO:0002574 thrombocyte differentiation(GO:0002574)
2.8 11.3 GO:2000171 negative regulation of dendrite development(GO:2000171)
2.8 8.4 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
2.7 18.6 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
2.6 28.9 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
2.6 17.9 GO:0042554 superoxide anion generation(GO:0042554)
2.5 5.0 GO:0006012 galactose metabolic process(GO:0006012)
2.5 12.5 GO:0035988 chondrocyte proliferation(GO:0035988)
2.4 14.4 GO:0032663 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
2.3 7.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
2.3 11.3 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
2.3 9.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
2.2 31.1 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
2.2 8.8 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
2.2 8.8 GO:0050851 antigen receptor-mediated signaling pathway(GO:0050851) B cell receptor signaling pathway(GO:0050853)
2.2 8.8 GO:1903292 protein localization to Golgi membrane(GO:1903292)
2.2 6.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) anterior lateral line neuromast hair cell development(GO:0035676)
2.2 49.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
2.2 6.5 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
2.1 25.1 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
2.0 12.2 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
2.0 12.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
2.0 8.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
2.0 11.7 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
1.9 9.5 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
1.9 5.7 GO:0072344 rescue of stalled ribosome(GO:0072344)
1.9 32.0 GO:0015693 magnesium ion transport(GO:0015693)
1.9 7.5 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
1.9 15.0 GO:0006111 regulation of gluconeogenesis(GO:0006111)
1.9 9.3 GO:0045824 negative regulation of innate immune response(GO:0045824)
1.9 5.6 GO:0046048 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
1.8 9.2 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
1.8 3.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
1.7 12.1 GO:0051705 multi-organism behavior(GO:0051705)
1.7 5.2 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
1.7 6.8 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
1.7 6.8 GO:2000383 ectodermal cell fate commitment(GO:0001712) ectodermal cell fate specification(GO:0001715) ectodermal cell differentiation(GO:0010668) regulation of ectodermal cell fate specification(GO:0042665) regulation of ectoderm development(GO:2000383)
1.6 24.7 GO:0043114 regulation of vascular permeability(GO:0043114)
1.6 6.6 GO:0071867 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
1.6 19.6 GO:0033198 response to ATP(GO:0033198)
1.6 21.0 GO:0007172 signal complex assembly(GO:0007172)
1.6 4.8 GO:1901216 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
1.6 8.1 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
1.6 29.9 GO:0008078 mesodermal cell migration(GO:0008078)
1.6 26.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
1.6 4.7 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
1.5 7.7 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
1.5 4.6 GO:1903358 regulation of Golgi organization(GO:1903358)
1.5 7.6 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
1.5 9.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
1.5 3.0 GO:0006465 signal peptide processing(GO:0006465)
1.5 5.9 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
1.5 7.4 GO:0033238 regulation of cellular amino acid metabolic process(GO:0006521) regulation of cellular amine metabolic process(GO:0033238)
1.5 14.7 GO:0051125 regulation of actin nucleation(GO:0051125)
1.5 4.4 GO:0042730 fibrinolysis(GO:0042730)
1.5 1.5 GO:0001818 negative regulation of cytokine production(GO:0001818)
1.4 8.7 GO:0010269 response to selenium ion(GO:0010269)
1.4 12.9 GO:0042113 B cell activation(GO:0042113)
1.4 15.4 GO:1901072 chitin catabolic process(GO:0006032) amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
1.4 79.8 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
1.4 20.8 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
1.4 11.0 GO:0036372 opsin transport(GO:0036372)
1.3 29.4 GO:0017121 phospholipid scrambling(GO:0017121)
1.3 8.0 GO:0032367 intracellular cholesterol transport(GO:0032367)
1.3 11.9 GO:0030104 water homeostasis(GO:0030104)
1.3 7.8 GO:0070650 actin filament bundle distribution(GO:0070650)
1.3 14.2 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
1.3 6.4 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
1.2 24.6 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
1.2 4.9 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
1.2 52.1 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
1.2 15.2 GO:0016601 Rac protein signal transduction(GO:0016601)
1.2 8.1 GO:0009188 ribonucleoside diphosphate biosynthetic process(GO:0009188)
1.2 15.0 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
1.1 6.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
1.1 9.2 GO:1900024 regulation of substrate adhesion-dependent cell spreading(GO:1900024) positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
1.1 4.6 GO:0002637 regulation of immunoglobulin production(GO:0002637) positive regulation of immunoglobulin production(GO:0002639)
1.1 10.2 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
1.1 12.3 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
1.1 3.3 GO:0021563 glossopharyngeal nerve development(GO:0021563)
1.1 23.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
1.1 7.8 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
1.1 25.3 GO:0051639 actin filament network formation(GO:0051639)
1.1 15.4 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
1.1 7.7 GO:0031048 chromatin silencing by small RNA(GO:0031048)
1.1 2.2 GO:0006670 sphingosine metabolic process(GO:0006670)
1.1 23.4 GO:0030593 neutrophil chemotaxis(GO:0030593)
1.1 11.7 GO:0035587 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
1.1 6.3 GO:0032218 riboflavin transport(GO:0032218)
1.0 4.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.0 4.1 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
1.0 2.1 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
1.0 5.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
1.0 9.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.0 9.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
1.0 2.0 GO:0060306 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
1.0 9.0 GO:0048566 embryonic digestive tract development(GO:0048566)
1.0 3.0 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
1.0 9.8 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
1.0 19.6 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
1.0 74.2 GO:0030048 actin filament-based movement(GO:0030048)
1.0 9.7 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
1.0 5.8 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
1.0 5.8 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.9 10.4 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.9 3.8 GO:0034605 cellular response to heat(GO:0034605)
0.9 6.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.9 4.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.9 4.7 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.9 9.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.9 7.5 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.9 28.0 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.9 22.3 GO:0042743 hydrogen peroxide metabolic process(GO:0042743)
0.9 4.6 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.9 13.0 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.9 12.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.9 2.8 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.9 4.6 GO:1990108 protein linear deubiquitination(GO:1990108)
0.9 3.7 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.9 10.9 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.9 26.1 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.9 4.5 GO:0003210 cardiac atrium formation(GO:0003210)
0.9 23.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.9 11.6 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.9 2.6 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.9 3.5 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.9 3.4 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.8 20.7 GO:0030149 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.8 2.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.8 23.0 GO:0051923 sulfation(GO:0051923)
0.8 2.5 GO:0042117 monocyte activation(GO:0042117)
0.8 5.7 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.8 12.1 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.8 11.3 GO:0090481 nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.8 4.8 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.8 14.3 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.8 13.5 GO:0034629 cellular protein complex localization(GO:0034629)
0.8 24.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.8 10.3 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.8 32.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.8 7.0 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.8 14.6 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.8 98.7 GO:0007160 cell-matrix adhesion(GO:0007160)
0.8 2.3 GO:0044246 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.8 6.8 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.8 6.1 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.8 3.8 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.8 6.0 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.7 7.4 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.7 5.9 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.7 16.8 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.7 2.9 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.7 1.4 GO:0034421 post-translational protein acetylation(GO:0034421)
0.7 26.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.7 5.7 GO:0090594 inflammatory response to wounding(GO:0090594)
0.7 9.3 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.7 4.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.7 8.4 GO:0019835 cytolysis(GO:0019835)
0.7 11.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.7 2.1 GO:0048211 Golgi vesicle docking(GO:0048211)
0.7 4.8 GO:0033628 regulation of cell adhesion mediated by integrin(GO:0033628)
0.7 4.8 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.7 14.9 GO:0032506 cytokinetic process(GO:0032506)
0.7 54.7 GO:0060348 bone development(GO:0060348)
0.7 30.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.7 2.0 GO:0034103 regulation of tissue remodeling(GO:0034103) regulation of bone remodeling(GO:0046850)
0.6 7.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.6 1.9 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.6 14.7 GO:0071222 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.6 3.8 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.6 4.4 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.6 5.0 GO:0048246 macrophage chemotaxis(GO:0048246)
0.6 6.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.6 3.1 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.6 29.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.6 1.9 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.6 2.5 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.6 4.9 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.6 26.7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.6 15.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.6 7.2 GO:0030183 B cell differentiation(GO:0030183)
0.6 4.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.6 3.0 GO:0030828 nitric oxide mediated signal transduction(GO:0007263) regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.6 2.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.6 3.6 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.6 2.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.6 2.3 GO:0006750 glutathione biosynthetic process(GO:0006750) nonribosomal peptide biosynthetic process(GO:0019184)
0.6 3.9 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.5 2.7 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.5 3.8 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.5 1.6 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.5 2.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.5 13.3 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.5 1.6 GO:0060420 regulation of heart growth(GO:0060420)
0.5 6.8 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.5 2.1 GO:0043096 adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096)
0.5 4.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.5 3.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.5 7.6 GO:0043462 regulation of ATPase activity(GO:0043462)
0.5 5.9 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.5 38.5 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.5 3.9 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.5 42.9 GO:0031101 fin regeneration(GO:0031101)
0.5 2.4 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.5 7.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.5 1.9 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.5 10.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.5 7.4 GO:0016075 rRNA catabolic process(GO:0016075)
0.5 3.2 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.5 42.6 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.5 2.3 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.5 1.4 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.4 4.9 GO:0003313 heart rudiment development(GO:0003313)
0.4 3.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.4 12.2 GO:0010632 regulation of epithelial cell migration(GO:0010632)
0.4 21.2 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.4 1.7 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.4 7.2 GO:0007032 endosome organization(GO:0007032)
0.4 20.8 GO:0060326 cell chemotaxis(GO:0060326)
0.4 7.9 GO:0019882 antigen processing and presentation(GO:0019882)
0.4 8.6 GO:1990798 pancreas regeneration(GO:1990798)
0.4 2.8 GO:0032475 otolith formation(GO:0032475)
0.4 12.1 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.4 6.1 GO:0061036 positive regulation of chondrocyte differentiation(GO:0032332) positive regulation of cartilage development(GO:0061036)
0.4 5.2 GO:0006801 superoxide metabolic process(GO:0006801)
0.4 7.2 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.4 6.8 GO:0006308 DNA catabolic process(GO:0006308)
0.4 3.6 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.4 11.5 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.4 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.4 5.3 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.4 1.1 GO:0045056 transcytosis(GO:0045056)
0.4 0.4 GO:0045058 T-helper cell lineage commitment(GO:0002295) T cell lineage commitment(GO:0002360) alpha-beta T cell lineage commitment(GO:0002363) positive T cell selection(GO:0043368) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) T cell selection(GO:0045058) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540)
0.4 10.9 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.4 4.5 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.4 11.7 GO:0019722 calcium-mediated signaling(GO:0019722)
0.4 11.3 GO:0009395 phospholipid catabolic process(GO:0009395)
0.4 17.6 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.4 4.4 GO:0051604 protein maturation(GO:0051604)
0.4 5.5 GO:0031641 regulation of myelination(GO:0031641)
0.4 30.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.4 1.8 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.4 6.9 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.4 15.8 GO:0050881 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.4 14.9 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.4 2.1 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.4 4.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.4 11.2 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.3 3.8 GO:0006611 protein export from nucleus(GO:0006611)
0.3 27.1 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.3 5.4 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.3 8.7 GO:0006884 cell volume homeostasis(GO:0006884)
0.3 9.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 8.4 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.3 6.1 GO:0009636 response to toxic substance(GO:0009636)
0.3 4.7 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.3 3.8 GO:0016486 peptide hormone processing(GO:0016486)
0.3 98.7 GO:0006955 immune response(GO:0006955)
0.3 4.1 GO:0006570 tyrosine metabolic process(GO:0006570)
0.3 4.1 GO:0097475 motor neuron migration(GO:0097475)
0.3 1.3 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.3 1.3 GO:1903232 melanosome assembly(GO:1903232)
0.3 10.5 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.3 60.3 GO:0009617 response to bacterium(GO:0009617)
0.3 2.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.3 9.2 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.3 1.5 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.3 7.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 72.1 GO:0043087 regulation of GTPase activity(GO:0043087)
0.3 3.7 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.3 2.3 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.3 1.7 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.3 8.2 GO:0051014 actin filament severing(GO:0051014)
0.3 1.1 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643) positive regulation of skeletal muscle fiber development(GO:0048743)
0.3 4.5 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.3 1.6 GO:0006999 nuclear pore organization(GO:0006999)
0.3 4.0 GO:0016203 muscle attachment(GO:0016203)
0.3 4.8 GO:0046427 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.3 2.6 GO:0034453 microtubule anchoring(GO:0034453)
0.3 7.3 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.3 1.3 GO:0090527 actin filament reorganization(GO:0090527)
0.3 3.1 GO:0010950 positive regulation of endopeptidase activity(GO:0010950) positive regulation of peptidase activity(GO:0010952)
0.3 2.3 GO:0070932 histone H3 deacetylation(GO:0070932)
0.3 10.3 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.3 18.1 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.3 16.6 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.2 3.5 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 2.5 GO:0071392 intracellular estrogen receptor signaling pathway(GO:0030520) cellular response to estradiol stimulus(GO:0071392)
0.2 6.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.2 5.9 GO:0050821 protein stabilization(GO:0050821)
0.2 4.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.2 11.9 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.2 6.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.2 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.2 4.4 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 1.6 GO:0031647 regulation of protein stability(GO:0031647)
0.2 2.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.2 4.0 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.2 1.7 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.2 1.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 1.2 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.2 1.6 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.2 6.6 GO:0032456 endocytic recycling(GO:0032456)
0.2 1.9 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.2 1.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 12.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.2 2.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2 24.3 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.2 17.2 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.2 6.3 GO:0006612 protein targeting to membrane(GO:0006612)
0.2 0.7 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.2 0.4 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.2 2.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 0.5 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.2 1.8 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.2 4.9 GO:0098542 defense response to other organism(GO:0098542)
0.2 0.9 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.2 0.3 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.2 4.0 GO:0032526 response to retinoic acid(GO:0032526)
0.2 5.2 GO:0072348 sulfur compound transport(GO:0072348)
0.2 1.4 GO:0008105 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.2 1.0 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 2.0 GO:0016926 protein desumoylation(GO:0016926)
0.2 4.3 GO:0003094 glomerular filtration(GO:0003094)
0.2 1.2 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.2 2.0 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.2 8.7 GO:0008360 regulation of cell shape(GO:0008360)
0.2 6.8 GO:0007596 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.2 7.3 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.2 10.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 1.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.9 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.0 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 1.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 6.2 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 5.3 GO:0048821 erythrocyte development(GO:0048821)
0.1 0.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422) primary miRNA processing(GO:0031053)
0.1 0.4 GO:1903173 fatty alcohol metabolic process(GO:1903173)
0.1 5.5 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.1 3.7 GO:0031103 axon regeneration(GO:0031103)
0.1 7.4 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.1 1.8 GO:0031033 myosin filament organization(GO:0031033)
0.1 7.3 GO:0009190 cyclic nucleotide biosynthetic process(GO:0009190)
0.1 1.6 GO:0035778 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.1 1.6 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.1 5.6 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.1 4.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 1.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 2.5 GO:0001817 regulation of cytokine production(GO:0001817)
0.1 2.5 GO:0014029 neural crest formation(GO:0014029)
0.1 5.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 2.3 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 7.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 40.8 GO:0006412 translation(GO:0006412) peptide biosynthetic process(GO:0043043)
0.1 1.6 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 0.5 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.1 7.1 GO:0045765 regulation of angiogenesis(GO:0045765)
0.1 1.7 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 0.6 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 1.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 13.7 GO:0072594 establishment of protein localization to organelle(GO:0072594)
0.1 1.6 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.1 5.5 GO:0006457 protein folding(GO:0006457)
0.1 1.2 GO:0010212 response to ionizing radiation(GO:0010212)
0.1 1.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.5 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 2.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 0.2 GO:0032988 spliceosomal complex disassembly(GO:0000390) ribonucleoprotein complex disassembly(GO:0032988)
0.1 1.1 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 0.2 GO:0046133 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) pyrimidine ribonucleoside catabolic process(GO:0046133)
0.1 1.0 GO:0034508 centromere complex assembly(GO:0034508)
0.1 0.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 2.8 GO:0010842 retina layer formation(GO:0010842)
0.1 0.6 GO:0033750 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.1 0.9 GO:0007044 cell-substrate junction assembly(GO:0007044) hemidesmosome assembly(GO:0031581)
0.1 0.6 GO:0007530 sex determination(GO:0007530)
0.1 1.0 GO:0001878 response to yeast(GO:0001878)
0.1 3.0 GO:0030903 notochord development(GO:0030903)
0.1 0.6 GO:0045010 actin nucleation(GO:0045010)
0.1 2.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 1.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 4.1 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.5 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.8 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.8 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 2.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.7 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.5 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 35.4 GO:0006508 proteolysis(GO:0006508)
0.0 0.5 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.3 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962) stress granule assembly(GO:0034063)
0.0 2.1 GO:0006310 DNA recombination(GO:0006310)
0.0 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.3 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.6 GO:0046460 triglyceride biosynthetic process(GO:0019432) neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.3 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0042417 phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) dopamine metabolic process(GO:0042417) catecholamine catabolic process(GO:0042424)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.4 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.3 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 27.1 GO:0097433 dense body(GO:0097433)
4.8 19.1 GO:0061702 inflammasome complex(GO:0061702)
3.8 22.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
3.7 11.1 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
3.6 14.4 GO:0019815 B cell receptor complex(GO:0019815)
3.4 10.2 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
3.4 60.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
3.0 3.0 GO:0045335 phagocytic vesicle(GO:0045335)
3.0 32.7 GO:0045095 keratin filament(GO:0045095)
2.6 18.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
2.2 17.9 GO:0043020 NADPH oxidase complex(GO:0043020)
2.2 22.4 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
2.1 6.2 GO:0043220 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
1.9 5.8 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
1.9 89.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
1.8 25.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
1.6 6.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
1.6 13.1 GO:0042613 MHC class II protein complex(GO:0042613)
1.6 6.5 GO:0098802 plasma membrane receptor complex(GO:0098802)
1.6 23.5 GO:0016328 lateral plasma membrane(GO:0016328)
1.5 9.3 GO:0042611 MHC protein complex(GO:0042611)
1.5 4.6 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
1.5 10.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
1.5 10.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.5 8.7 GO:0031428 box C/D snoRNP complex(GO:0031428)
1.4 73.6 GO:0005902 microvillus(GO:0005902)
1.4 5.4 GO:0008537 proteasome activator complex(GO:0008537)
1.3 2.7 GO:0043614 multi-eIF complex(GO:0043614)
1.3 8.0 GO:0008385 IkappaB kinase complex(GO:0008385)
1.3 7.9 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
1.3 3.9 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
1.3 13.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.3 1.3 GO:0071564 npBAF complex(GO:0071564)
1.3 7.5 GO:0031258 lamellipodium membrane(GO:0031258)
1.2 6.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
1.2 3.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.1 68.0 GO:0022626 cytosolic ribosome(GO:0022626)
1.1 3.3 GO:0034457 Mpp10 complex(GO:0034457)
1.0 21.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
1.0 6.2 GO:0034719 SMN-Sm protein complex(GO:0034719)
1.0 15.2 GO:0030057 desmosome(GO:0030057)
1.0 2.9 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
1.0 3.9 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.9 257.3 GO:0005764 lysosome(GO:0005764)
0.9 12.6 GO:0031209 SCAR complex(GO:0031209)
0.9 6.9 GO:0000796 condensin complex(GO:0000796)
0.9 11.1 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.8 3.3 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.8 16.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.8 19.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.8 14.6 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.7 5.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.7 2.9 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.7 4.4 GO:0070876 SOSS complex(GO:0070876)
0.6 1.3 GO:0031085 BLOC-3 complex(GO:0031085)
0.6 1.9 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.6 52.4 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.6 3.0 GO:0000814 ESCRT II complex(GO:0000814)
0.6 73.8 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.6 7.8 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.6 4.8 GO:0001772 immunological synapse(GO:0001772)
0.6 43.5 GO:0030027 lamellipodium(GO:0030027)
0.6 7.0 GO:0043235 receptor complex(GO:0043235)
0.6 65.8 GO:0005884 actin filament(GO:0005884)
0.6 9.2 GO:0036038 MKS complex(GO:0036038)
0.6 11.3 GO:0009925 basal plasma membrane(GO:0009925)
0.6 15.6 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.6 4.4 GO:0061700 GATOR2 complex(GO:0061700)
0.5 1.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.5 30.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.5 31.1 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.5 2.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.5 4.8 GO:0030904 retromer complex(GO:0030904)
0.5 7.5 GO:0000815 ESCRT III complex(GO:0000815)
0.5 6.3 GO:0043296 apical junction complex(GO:0043296)
0.5 1.6 GO:1990879 CST complex(GO:1990879)
0.5 10.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.5 59.6 GO:0030055 cell-substrate junction(GO:0030055)
0.5 4.6 GO:0071797 LUBAC complex(GO:0071797)
0.5 1.4 GO:0033186 CAF-1 complex(GO:0033186)
0.5 6.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.5 10.2 GO:0032587 ruffle membrane(GO:0032587)
0.5 3.7 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.5 11.0 GO:0045180 basal cortex(GO:0045180)
0.5 2.7 GO:0031262 Ndc80 complex(GO:0031262)
0.5 17.1 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.4 21.9 GO:0031901 early endosome membrane(GO:0031901)
0.4 17.8 GO:0016528 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.4 5.8 GO:0005903 brush border(GO:0005903)
0.4 103.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.4 2.0 GO:0034359 mature chylomicron(GO:0034359)
0.4 0.4 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.4 1.6 GO:0097255 R2TP complex(GO:0097255)
0.4 10.2 GO:0032040 small-subunit processome(GO:0032040)
0.4 5.9 GO:0005686 U2 snRNP(GO:0005686)
0.4 1.8 GO:0018444 translation release factor complex(GO:0018444)
0.4 1.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.3 5.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.3 26.2 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.3 1.6 GO:0070390 transcription export complex 2(GO:0070390)
0.3 13.6 GO:0030141 secretory granule(GO:0030141)
0.3 1.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.3 3.3 GO:0034451 centriolar satellite(GO:0034451)
0.3 3.6 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.3 11.0 GO:0016514 SWI/SNF complex(GO:0016514)
0.3 5.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.3 1.7 GO:0005771 multivesicular body(GO:0005771)
0.3 1.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 1.1 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.3 26.2 GO:0016459 myosin complex(GO:0016459)
0.3 4.8 GO:0042555 MCM complex(GO:0042555)
0.3 1.9 GO:0005801 cis-Golgi network(GO:0005801)
0.3 3.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 1.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 3.0 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 2.0 GO:0032797 SMN complex(GO:0032797)
0.2 23.8 GO:0005604 basement membrane(GO:0005604)
0.2 20.8 GO:0005802 trans-Golgi network(GO:0005802)
0.2 3.2 GO:0017119 Golgi transport complex(GO:0017119)
0.2 1.7 GO:0070652 HAUS complex(GO:0070652)
0.2 8.3 GO:0016324 apical plasma membrane(GO:0016324)
0.2 0.7 GO:0000323 lytic vacuole(GO:0000323)
0.2 1.4 GO:0070695 FHF complex(GO:0070695)
0.2 27.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 11.5 GO:0005811 lipid particle(GO:0005811)
0.2 2.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 25.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.2 1.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 9.4 GO:0030139 endocytic vesicle(GO:0030139)
0.2 2.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 1.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 2.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.2 15.2 GO:0070382 exocytic vesicle(GO:0070382)
0.2 3.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 5.4 GO:0005839 proteasome core complex(GO:0005839)
0.2 2.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 6.9 GO:0048786 presynaptic active zone(GO:0048786)
0.2 1.6 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 8.3 GO:0016592 mediator complex(GO:0016592)
0.2 11.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 4.8 GO:0005770 late endosome(GO:0005770)
0.2 21.6 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.2 5.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 1.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.6 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 5.1 GO:0005876 spindle microtubule(GO:0005876)
0.1 4.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 2.3 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1 1.1 GO:0042627 chylomicron(GO:0042627)
0.1 5.2 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.1 24.8 GO:0012506 vesicle membrane(GO:0012506)
0.1 8.9 GO:0010008 endosome membrane(GO:0010008)
0.1 5.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 7.7 GO:0030880 RNA polymerase complex(GO:0030880)
0.1 1.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 5.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 7.5 GO:0098562 cytoplasmic side of membrane(GO:0098562)
0.1 24.9 GO:0000139 Golgi membrane(GO:0000139)
0.1 2.5 GO:0000145 exocyst(GO:0000145)
0.1 14.3 GO:0009986 cell surface(GO:0009986)
0.1 4.1 GO:0005769 early endosome(GO:0005769)
0.1 143.7 GO:0005576 extracellular region(GO:0005576)
0.1 6.2 GO:0030054 cell junction(GO:0030054)
0.1 1.7 GO:0098978 glutamatergic synapse(GO:0098978)
0.1 1.2 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.6 GO:0015030 Cajal body(GO:0015030)
0.1 1.3 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 15.5 GO:0000785 chromatin(GO:0000785)
0.1 5.0 GO:0016607 nuclear speck(GO:0016607)
0.0 5.1 GO:0030425 dendrite(GO:0030425)
0.0 2.0 GO:0072686 mitotic spindle(GO:0072686)
0.0 3.7 GO:0036064 ciliary basal body(GO:0036064)
0.0 4.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 5.2 GO:0005635 nuclear envelope(GO:0005635)
0.0 1.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.9 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.7 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 2.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 18.5 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 1.1 GO:0005768 endosome(GO:0005768)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 78.1 GO:0016021 integral component of membrane(GO:0016021)
0.0 8.8 GO:0005886 plasma membrane(GO:0005886)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.3 51.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
5.6 16.7 GO:0004557 alpha-galactosidase activity(GO:0004557)
5.5 38.8 GO:0003993 acid phosphatase activity(GO:0003993)
5.4 27.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
5.3 16.0 GO:0008179 adenylate cyclase binding(GO:0008179)
5.2 20.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
4.6 18.3 GO:0003796 lysozyme activity(GO:0003796)
4.5 17.8 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
4.4 13.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
4.4 17.6 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
4.1 28.9 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
4.0 12.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
3.5 24.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
3.4 10.2 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
3.2 9.6 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
3.1 9.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
3.1 12.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
3.0 9.1 GO:0047690 aspartyltransferase activity(GO:0047690)
3.0 27.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
2.8 19.9 GO:0004974 leukotriene receptor activity(GO:0004974)
2.7 13.7 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
2.6 7.9 GO:0045545 syndecan binding(GO:0045545)
2.5 25.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
2.5 15.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
2.5 7.5 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
2.4 14.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
2.4 9.5 GO:0051380 norepinephrine binding(GO:0051380)
2.4 11.9 GO:0070573 metallodipeptidase activity(GO:0070573)
2.4 21.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
2.3 21.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
2.2 6.5 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
2.2 23.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
2.1 29.5 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
2.1 24.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
2.0 8.0 GO:0008384 IkappaB kinase activity(GO:0008384)
1.9 38.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
1.9 13.5 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
1.9 5.8 GO:0033897 ribonuclease T2 activity(GO:0033897)
1.9 11.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
1.9 7.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
1.9 5.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.9 5.6 GO:0009041 uridylate kinase activity(GO:0009041)
1.8 18.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
1.8 5.5 GO:0004301 epoxide hydrolase activity(GO:0004301)
1.7 7.0 GO:0070643 vitamin D 25-hydroxylase activity(GO:0070643)
1.7 6.9 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
1.7 15.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
1.7 13.5 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
1.7 6.7 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
1.6 19.6 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.6 16.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
1.5 7.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
1.5 15.0 GO:0050700 CARD domain binding(GO:0050700)
1.5 7.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
1.5 19.4 GO:0051117 ATPase binding(GO:0051117)
1.5 31.2 GO:0045125 bioactive lipid receptor activity(GO:0045125)
1.4 11.4 GO:0048019 receptor antagonist activity(GO:0048019)
1.4 15.4 GO:0004568 chitinase activity(GO:0004568)
1.4 12.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.4 17.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
1.3 9.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
1.3 24.8 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
1.3 13.0 GO:0004530 deoxyribonuclease I activity(GO:0004530)
1.3 9.1 GO:0004962 endothelin receptor activity(GO:0004962)
1.3 3.8 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
1.3 3.8 GO:0070051 fibrinogen binding(GO:0070051)
1.3 10.1 GO:0015157 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
1.2 56.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
1.2 3.7 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
1.2 3.6 GO:0016748 succinyltransferase activity(GO:0016748)
1.2 9.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
1.2 8.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
1.1 11.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
1.1 24.6 GO:0042289 MHC class II protein binding(GO:0042289)
1.1 12.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
1.1 74.1 GO:0005044 scavenger receptor activity(GO:0005044)
1.1 3.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
1.1 12.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
1.1 59.6 GO:0000146 microfilament motor activity(GO:0000146)
1.1 12.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
1.1 5.4 GO:0008097 5S rRNA binding(GO:0008097)
1.1 22.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
1.1 7.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
1.1 4.2 GO:0004998 transferrin receptor activity(GO:0004998)
1.1 9.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
1.1 6.3 GO:0032217 riboflavin transporter activity(GO:0032217)
1.0 37.5 GO:0005540 hyaluronic acid binding(GO:0005540)
1.0 11.8 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.0 5.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
1.0 4.8 GO:0098639 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.9 21.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.9 4.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.9 3.7 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.9 13.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.9 13.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.9 4.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.9 3.5 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.9 20.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.9 5.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.9 5.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.8 4.2 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.8 2.5 GO:0036310 annealing helicase activity(GO:0036310)
0.8 20.7 GO:0099604 ligand-gated calcium channel activity(GO:0099604)
0.8 8.3 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.8 12.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.8 2.5 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.8 5.7 GO:0019809 spermidine binding(GO:0019809)
0.8 64.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.8 17.9 GO:0005523 tropomyosin binding(GO:0005523)
0.8 158.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.8 8.0 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.8 4.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.8 3.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.8 3.9 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.8 3.8 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.8 5.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.8 5.3 GO:0015923 mannosidase activity(GO:0015923)
0.8 3.0 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.7 11.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.7 11.5 GO:0016502 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.7 7.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.7 1.4 GO:0051920 peroxiredoxin activity(GO:0051920)
0.7 2.1 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.7 2.0 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.7 9.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.7 17.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.6 22.8 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.6 4.4 GO:0070728 leucine binding(GO:0070728)
0.6 3.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.6 1.9 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.6 8.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.6 1.9 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.6 2.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.6 1.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.6 84.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.6 10.2 GO:0005080 protein kinase C binding(GO:0005080)
0.6 2.9 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.6 28.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.6 3.5 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.6 5.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.6 1.7 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.6 7.9 GO:0031386 protein tag(GO:0031386)
0.6 2.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.6 27.6 GO:0004601 peroxidase activity(GO:0004601)
0.6 5.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.5 2.7 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.5 6.6 GO:0005158 insulin receptor binding(GO:0005158)
0.5 2.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.5 5.4 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.5 3.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.5 24.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.5 20.1 GO:0019956 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.5 2.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.5 2.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.5 9.9 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.5 10.3 GO:0070411 I-SMAD binding(GO:0070411)
0.5 4.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.5 3.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.5 6.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.5 5.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.5 6.0 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.5 2.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.5 57.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.5 1.9 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.5 6.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.5 12.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.5 1.8 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.5 5.9 GO:0070035 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.4 9.0 GO:0097602 cullin family protein binding(GO:0097602)
0.4 4.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.4 24.8 GO:0004521 endoribonuclease activity(GO:0004521)
0.4 3.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.4 8.8 GO:0031369 translation initiation factor binding(GO:0031369)
0.4 1.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.4 131.1 GO:0051015 actin filament binding(GO:0051015)
0.4 4.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 9.7 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.4 4.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.4 3.6 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.4 83.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.4 7.5 GO:0030515 snoRNA binding(GO:0030515)
0.4 7.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.4 5.1 GO:0005537 mannose binding(GO:0005537)
0.4 4.7 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.4 1.9 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.4 2.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.4 10.2 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.4 144.7 GO:0030695 GTPase regulator activity(GO:0030695)
0.4 1.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.4 12.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.4 2.9 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.4 4.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4 7.6 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.4 1.8 GO:0046592 polyamine oxidase activity(GO:0046592)
0.4 18.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.4 2.5 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.4 3.5 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.3 8.7 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.3 6.9 GO:0001671 ATPase activator activity(GO:0001671)
0.3 7.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 6.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.3 22.4 GO:0032934 sterol binding(GO:0032934)
0.3 1.3 GO:0034046 poly(G) binding(GO:0034046)
0.3 2.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 2.9 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3 1.6 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.3 3.4 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.3 2.2 GO:1903924 estradiol binding(GO:1903924)
0.3 3.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.3 3.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 1.5 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.3 8.5 GO:0030165 PDZ domain binding(GO:0030165)
0.3 4.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.3 22.3 GO:0004896 cytokine receptor activity(GO:0004896)
0.3 26.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.3 3.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.3 2.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.3 1.0 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 0.8 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.3 1.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 2.0 GO:0070325 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.2 5.5 GO:0019894 kinesin binding(GO:0019894)
0.2 3.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 0.7 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.2 3.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 32.7 GO:0005125 cytokine activity(GO:0005125)
0.2 3.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 9.5 GO:0050661 NADP binding(GO:0050661)
0.2 2.8 GO:0019843 rRNA binding(GO:0019843)
0.2 0.7 GO:0031701 angiotensin receptor binding(GO:0031701)
0.2 14.1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.2 1.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.2 3.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 122.0 GO:0005525 GTP binding(GO:0005525)
0.2 6.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 3.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 4.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 0.7 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 0.5 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 0.5 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 10.9 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.2 4.7 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.2 1.0 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.2 8.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 1.0 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.2 1.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 4.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 14.7 GO:0019208 phosphatase regulator activity(GO:0019208)
0.2 1.9 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.2 2.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 4.1 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 3.0 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 5.4 GO:0005126 cytokine receptor binding(GO:0005126)
0.1 0.9 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 4.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 3.0 GO:0004875 complement receptor activity(GO:0004875)
0.1 1.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 4.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 4.0 GO:0048029 monosaccharide binding(GO:0048029)
0.1 4.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 11.6 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 1.8 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 3.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 4.4 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 1.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 6.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 3.6 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.1 1.5 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 0.7 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 1.9 GO:0016896 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.1 2.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 2.0 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.1 4.5 GO:0046332 SMAD binding(GO:0046332)
0.1 60.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 1.8 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 6.4 GO:0043130 ubiquitin-like protein binding(GO:0032182) ubiquitin binding(GO:0043130)
0.1 5.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 1.7 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 2.4 GO:0003684 damaged DNA binding(GO:0003684)
0.1 15.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 2.7 GO:0043022 ribosome binding(GO:0043022)
0.1 12.5 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 1.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 4.6 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.1 3.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.4 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.8 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 11.9 GO:0030246 carbohydrate binding(GO:0030246)
0.1 2.7 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 1.2 GO:0008198 ferrous iron binding(GO:0008198)
0.1 0.9 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 5.1 GO:0005506 iron ion binding(GO:0005506)
0.1 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 7.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 6.8 GO:0004386 helicase activity(GO:0004386)
0.0 0.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 16.1 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 8.8 GO:0003779 actin binding(GO:0003779)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.4 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 20.8 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 16.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
2.7 8.1 PID ENDOTHELIN PATHWAY Endothelins
2.3 18.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.7 86.9 PID RAC1 PATHWAY RAC1 signaling pathway
1.7 64.3 PID EPO PATHWAY EPO signaling pathway
1.6 29.1 PID TRAIL PATHWAY TRAIL signaling pathway
1.6 17.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
1.6 35.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
1.5 8.9 PID VEGFR1 PATHWAY VEGFR1 specific signals
1.5 29.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
1.4 24.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
1.3 18.2 PID ALK2 PATHWAY ALK2 signaling events
1.3 24.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
1.2 25.8 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
1.2 9.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
1.2 26.7 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
1.2 18.9 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
1.1 4.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
1.1 12.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
1.1 9.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
1.1 7.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.0 14.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
1.0 15.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.0 22.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.9 3.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.9 17.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.8 35.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.8 13.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.8 5.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.7 25.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.7 4.3 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.7 9.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.7 3.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.6 6.4 PID BCR 5PATHWAY BCR signaling pathway
0.6 16.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.6 8.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.6 15.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.5 7.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.5 10.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.5 10.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.4 12.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.4 13.8 PID AURORA B PATHWAY Aurora B signaling
0.4 6.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.4 1.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.4 1.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.4 3.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.4 6.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 3.8 PID FGF PATHWAY FGF signaling pathway
0.3 4.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.3 2.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.3 4.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.3 8.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.3 0.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.3 23.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.3 21.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 2.9 PID IL1 PATHWAY IL1-mediated signaling events
0.2 3.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 35.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.2 7.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 3.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 1.3 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.2 7.7 PID E2F PATHWAY E2F transcription factor network
0.2 22.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 6.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 1.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.3 PID ARF 3PATHWAY Arf1 pathway
0.1 1.8 PID P73PATHWAY p73 transcription factor network
0.1 1.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.1 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 27.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
4.2 50.7 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
3.8 19.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
3.5 24.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
3.1 34.5 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
2.8 30.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
2.8 19.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
2.7 21.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
2.6 23.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
2.3 18.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
2.2 12.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
1.9 3.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.9 28.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
1.8 94.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
1.7 17.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
1.6 12.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
1.5 11.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
1.5 2.9 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
1.4 5.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
1.3 26.0 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
1.3 2.6 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
1.1 10.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
1.1 4.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.1 11.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
1.0 29.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
1.0 72.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
1.0 6.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
1.0 1.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
1.0 3.8 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.9 19.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.9 8.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.9 2.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.9 8.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.9 10.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.8 8.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.8 16.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.8 28.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.8 85.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.8 6.2 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.8 26.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.7 8.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.7 10.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.7 8.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.7 7.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.7 16.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.7 8.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.6 1.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.6 3.8 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.6 4.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.6 8.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.6 10.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.5 13.6 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.5 5.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.5 8.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.5 10.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.5 6.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.5 12.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.5 5.8 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.4 7.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.4 7.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.4 3.6 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.4 4.2 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.4 4.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.4 28.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.4 3.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.4 1.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 1.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 5.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.3 3.0 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.3 21.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 4.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.3 6.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.3 4.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.3 3.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.3 2.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3 12.0 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.3 4.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.3 3.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 5.2 REACTOME TRANSLATION Genes involved in Translation
0.2 1.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 2.0 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.2 7.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.2 3.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 3.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 9.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.2 1.7 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.2 3.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 2.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 8.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 4.8 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.2 1.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 1.9 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.2 2.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 8.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.2 6.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 3.0 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.2 2.3 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants
0.1 1.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 3.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 3.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 5.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.5 REACTOME OPSINS Genes involved in Opsins
0.1 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.2 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 0.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.5 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.1 0.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 2.1 REACTOME S PHASE Genes involved in S Phase
0.1 0.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.0 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.0 0.5 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding