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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for stat4

Z-value: 0.80

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Transcription factors associated with stat4

Gene Symbol Gene ID Gene Info
stat4
ENSDARG00000028731 signal transducer and activator of transcription 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
stat4dr11_v1_chr9_+_41156818_411568180.381.3e-04Click!

Activity profile of stat4 motif

Sorted Z-values of stat4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_12950507 9.90 ENSDART00000067629
ENSDART00000158004
saa
serum amyloid A
chr16_-_36834505 7.91 ENSDART00000141275
ENSDART00000139588
ENSDART00000041993
pnp4b
purine nucleoside phosphorylase 4b
chr13_+_13681681 7.39 ENSDART00000057825
cfd
complement factor D (adipsin)
chr6_+_41503854 7.35 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cish
cytokine inducible SH2-containing protein
chr17_+_30591287 6.94 ENSDART00000154243
si:dkey-190l8.2
si:dkey-190l8.2
chr13_+_2908764 6.72 ENSDART00000162362
wu:fj16a03
wu:fj16a03
chr2_+_4207209 6.56 ENSDART00000157903
ENSDART00000166476
gata6
GATA binding protein 6
chr17_-_10838434 6.22 ENSDART00000064597
lgals3b
lectin, galactoside binding soluble 3b
chr5_-_26118855 5.92 ENSDART00000009028
ela3l
elastase 3 like
chr2_-_10098191 5.85 ENSDART00000138081
bcl6ab
B-cell CLL/lymphoma 6a, genome duplicate b
chr7_+_48870496 5.45 ENSDART00000009642
igf2a
insulin-like growth factor 2a
chr21_-_22715297 5.34 ENSDART00000065548
c1qb
complement component 1, q subcomponent, B chain
chr14_-_33278084 5.32 ENSDART00000132850
stard14
START domain containing 14
chr10_-_25823258 5.32 ENSDART00000064327
ftr54
finTRIM family, member 54
chr2_+_45159855 5.20 ENSDART00000056333
CU929150.1

chr5_+_37978501 5.18 ENSDART00000012050
apoa1a
apolipoprotein A-Ia
chr19_+_10331325 5.05 ENSDART00000143930
tmem238a
transmembrane protein 238a
chr5_-_57624425 4.99 ENSDART00000167892
zgc:193711
zgc:193711
chr1_-_6085750 4.82 ENSDART00000138891
si:ch1073-345a8.1
si:ch1073-345a8.1
chr16_+_50289916 4.49 ENSDART00000168861
ENSDART00000167332
hamp
hepcidin antimicrobial peptide
chr5_-_42878178 4.44 ENSDART00000162981
CXCL11 (1 of many)
C-X-C motif chemokine ligand 11
chr17_-_12498096 4.39 ENSDART00000149551
ENSDART00000105215
ENSDART00000191207
emilin1b
elastin microfibril interfacer 1b
chr16_+_38394371 4.39 ENSDART00000137954
cd83
CD83 molecule
chr23_-_31763753 4.36 ENSDART00000053399
aldh8a1
aldehyde dehydrogenase 8 family, member A1
chr9_-_16062938 4.34 ENSDART00000099479
crfb4
cytokine receptor family member b4
chr19_-_3821678 4.26 ENSDART00000169639
si:dkey-206d17.12
si:dkey-206d17.12
chr25_-_8602437 4.24 ENSDART00000171200
rhcgb
Rh family, C glycoprotein b
chr16_-_36099492 4.12 ENSDART00000180905
CU499336.2

chr21_+_45626136 4.11 ENSDART00000158742
irf1b
interferon regulatory factor 1b
chr21_+_25777425 4.08 ENSDART00000021620
cldnd
claudin d
chr8_-_38159805 4.05 ENSDART00000112331
ENSDART00000180006
adgra2
adhesion G protein-coupled receptor A2
chr16_-_11859309 4.04 ENSDART00000145754
cxcr3.1
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr2_+_26288301 3.97 ENSDART00000017668
ptbp1a
polypyrimidine tract binding protein 1a
chr22_+_30631072 3.93 ENSDART00000059970
zmp:0000000606
zmp:0000000606
chr3_-_32275975 3.91 ENSDART00000178448
cpt1cb
carnitine palmitoyltransferase 1Cb
chr12_-_37299646 3.89 ENSDART00000146142
ENSDART00000085201
pmp22b
peripheral myelin protein 22b
chr7_+_65673885 3.83 ENSDART00000169182
parvab
parvin, alpha b
chr5_+_20421539 3.82 ENSDART00000164499
selplg
selectin P ligand
chr11_-_11882982 3.79 ENSDART00000190853
wipf2a
WAS/WASL interacting protein family, member 2a
chr2_-_42035250 3.75 ENSDART00000056460
ENSDART00000140788
gbp1
guanylate binding protein 1
chr20_+_18994059 3.73 ENSDART00000152380
tdh
L-threonine dehydrogenase
chr10_+_36650222 3.72 ENSDART00000126963
ucp3
uncoupling protein 3
chr4_-_12725513 3.72 ENSDART00000132286
mgst1.2
microsomal glutathione S-transferase 1.2
chr2_+_42005217 3.65 ENSDART00000143562
gbp2
guanylate binding protein 2
chr2_+_4402765 3.65 ENSDART00000159525
bambib
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b
chr3_+_36646054 3.57 ENSDART00000170013
ENSDART00000159948
gspt1l
G1 to S phase transition 1, like
chr6_-_7439490 3.56 ENSDART00000188825
fkbp11
FK506 binding protein 11
chr15_+_5088210 3.54 ENSDART00000183423
mxf
myxovirus (influenza virus) resistance F
chr12_+_26435918 3.47 ENSDART00000006908
itgb3b
integrin beta 3b
chr8_+_39795918 3.42 ENSDART00000143413
si:ch211-170d8.2
si:ch211-170d8.2
chr1_+_12177195 3.41 ENSDART00000146842
ENSDART00000142081
stra6l
STRA6-like
chr9_+_41218967 3.40 ENSDART00000000280
ENSDART00000145674
stat1b
signal transducer and activator of transcription 1b
chr24_-_26820698 3.37 ENSDART00000147788
fndc3bb
fibronectin type III domain containing 3Bb
chr4_+_76735113 3.33 ENSDART00000075602
ms4a17a.6
membrane-spanning 4-domains, subfamily A, member 17A.6
chr15_+_11883804 3.27 ENSDART00000163255
gpr184
G protein-coupled receptor 184
chr6_-_54179860 3.22 ENSDART00000164283
rps10
ribosomal protein S10
chr7_-_50764714 3.21 ENSDART00000110283
iqgap1
IQ motif containing GTPase activating protein 1
chr20_+_18993452 3.16 ENSDART00000025509
tdh
L-threonine dehydrogenase
chr8_+_28467893 3.16 ENSDART00000189724
slc52a3
solute carrier family 52 (riboflavin transporter), member 3
chr10_+_8401929 3.12 ENSDART00000059028
hvcn1
hydrogen voltage-gated channel 1
chr7_+_26167420 3.12 ENSDART00000173941
si:ch211-196f2.6
si:ch211-196f2.6
chr18_+_30567945 3.07 ENSDART00000078894
irf8
interferon regulatory factor 8
chr18_+_18863167 3.03 ENSDART00000091094
pllp
plasmolipin
chr5_-_37959874 3.02 ENSDART00000031719
mpzl2b
myelin protein zero-like 2b
chr15_+_934660 3.01 ENSDART00000154248
si:dkey-77f5.10
si:dkey-77f5.10
chr16_-_21785261 3.00 ENSDART00000078858
si:ch73-86n18.1
si:ch73-86n18.1
chr8_-_18203092 2.91 ENSDART00000140620
elovl8b
ELOVL fatty acid elongase 8b
chr1_-_24458057 2.88 ENSDART00000140197
ENSDART00000181286
sh3d19
SH3 domain containing 19
chr9_+_44994214 2.85 ENSDART00000141434
retsatl
retinol saturase (all-trans-retinol 13,14-reductase) like
chr18_-_3527686 2.83 ENSDART00000169049
capn5a
calpain 5a
chr7_-_26518086 2.81 ENSDART00000058913
eif4a1a
eukaryotic translation initiation factor 4A1A
chr11_-_17964525 2.81 ENSDART00000018948
cishb
cytokine inducible SH2-containing protein b
chr25_+_16312258 2.79 ENSDART00000064187
parvaa
parvin, alpha a
chr6_-_23931442 2.75 ENSDART00000160547
sec16b
SEC16 homolog B, endoplasmic reticulum export factor
chr13_-_31647323 2.73 ENSDART00000135381
six4a
SIX homeobox 4a
chr25_+_11281970 2.70 ENSDART00000180094
AKAP13
si:dkey-187e18.1
chr23_-_33558161 2.68 ENSDART00000018301
itga5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr14_+_33329420 2.66 ENSDART00000171090
ENSDART00000164062
sowahd
sosondowah ankyrin repeat domain family d
chr11_+_14286160 2.61 ENSDART00000166236
si:ch211-262i1.3
si:ch211-262i1.3
chr1_-_38171648 2.60 ENSDART00000137451
ENSDART00000047159
hmgb2a
high mobility group box 2a
chr23_+_10469955 2.60 ENSDART00000140557
tns2a
tensin 2a
chr8_-_18203274 2.58 ENSDART00000134078
ENSDART00000180235
ENSDART00000080006
ENSDART00000125418
ENSDART00000142114
elovl8b
ELOVL fatty acid elongase 8b
chr22_+_20427170 2.57 ENSDART00000136744
foxq2
forkhead box Q2
chr24_-_17039638 2.56 ENSDART00000048823
c8g
complement component 8, gamma polypeptide
chr21_-_32060993 2.53 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr21_-_11970199 2.50 ENSDART00000114524
nop56
NOP56 ribonucleoprotein homolog
chr21_+_39197418 2.45 ENSDART00000076000
cpdb
carboxypeptidase D, b
chr7_-_60096318 2.42 ENSDART00000189125
BX511067.1

chr2_+_42005475 2.41 ENSDART00000056461
gbp2
guanylate binding protein 2
chr7_-_28696556 2.39 ENSDART00000148822
adgrg1
adhesion G protein-coupled receptor G1
chr14_+_28473173 2.30 ENSDART00000017075
xiap
X-linked inhibitor of apoptosis
chr23_+_17417539 2.29 ENSDART00000182605
BX649300.2

chr24_-_25256670 2.29 ENSDART00000126270
hhla2b.1
HERV-H LTR-associating 2b, tandem duplicate 1
chr5_+_43870389 2.28 ENSDART00000141002
zgc:112966
zgc:112966
chr17_-_45386823 2.27 ENSDART00000156002
tmem206
transmembrane protein 206
chr3_-_34098731 2.27 ENSDART00000150999
ighv5-3
immunoglobulin heavy variable 5-3
chr14_-_32631519 2.25 ENSDART00000167282
ENSDART00000052938
atp11c
ATPase phospholipid transporting 11C
chr23_+_1216215 2.22 ENSDART00000165957
utrn
utrophin
chr9_+_29992271 2.22 ENSDART00000188199
cmss1
cms1 ribosomal small subunit homolog (yeast)
chr6_+_39923052 2.22 ENSDART00000149019
itpr1a
inositol 1,4,5-trisphosphate receptor, type 1a
chr5_+_19261687 2.22 ENSDART00000139401
atp8b5a
ATPase phospholipid transporting 8B5a
chr6_+_52947186 2.20 ENSDART00000155831
uba7
ubiquitin-like modifier activating enzyme 7
chr4_-_13518381 2.19 ENSDART00000067153
ifng1-1
interferon, gamma 1-1
chr22_-_13165186 2.19 ENSDART00000105762
ahr2
aryl hydrocarbon receptor 2
chr8_-_20838342 2.19 ENSDART00000141345
si:ch211-133l5.7
si:ch211-133l5.7
chr3_-_31879201 2.18 ENSDART00000076189
zgc:171779
zgc:171779
chr18_-_3527988 2.16 ENSDART00000157669
capn5a
calpain 5a
chr21_+_39197628 2.15 ENSDART00000113607
cpdb
carboxypeptidase D, b
chr6_+_7322587 2.13 ENSDART00000065500
abcc4
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr7_-_69121896 2.11 ENSDART00000130227
crispld2
cysteine-rich secretory protein LCCL domain containing 2
chr19_+_7938121 2.11 ENSDART00000140053
ENSDART00000146649
si:dkey-266f7.5
si:dkey-266f7.5
chr16_+_21789703 2.10 ENSDART00000153617
trim108
tripartite motif containing 108
chr5_+_19261391 2.06 ENSDART00000089173
atp8b5a
ATPase phospholipid transporting 8B5a
chr15_-_18200358 2.02 ENSDART00000158569
si:ch211-247l8.8
si:ch211-247l8.8
chr9_+_15890558 2.02 ENSDART00000144032
si:dkey-14o1.20
si:dkey-14o1.20
chr19_+_19762183 1.99 ENSDART00000163611
ENSDART00000187604
hoxa3a
homeobox A3a
chr22_-_13350240 1.98 ENSDART00000154095
ENSDART00000155118
si:ch211-227m13.1
si:ch211-227m13.1
chr16_-_22585289 1.96 ENSDART00000134239
ENSDART00000193959
ENSDART00000077998
si:dkey-238m4.3
cgna
si:dkey-238m4.3
cingulin a
chr16_-_27564256 1.95 ENSDART00000078297
zgc:153215
zgc:153215
chr20_-_43775495 1.95 ENSDART00000100610
ENSDART00000149001
ENSDART00000148809
ENSDART00000100608
matn3a
matrilin 3a
chr24_-_26485098 1.95 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eif5a
eukaryotic translation initiation factor 5A
chr19_-_808265 1.94 ENSDART00000082454
glmp
glycosylated lysosomal membrane protein
chr23_-_5783421 1.94 ENSDART00000131521
ENSDART00000019455
csrp1a
cysteine and glycine-rich protein 1a
chr15_+_20529197 1.93 ENSDART00000060935
ENSDART00000137926
ENSDART00000140087
tnfaip1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr9_+_29616854 1.93 ENSDART00000033902
ENSDART00000143493
phf11
PHD finger protein 11
chr20_+_27427112 1.92 ENSDART00000153459
si:dkey-22l1.1
si:dkey-22l1.1
chr22_-_28645676 1.92 ENSDART00000005883
jagn1b
jagunal homolog 1b
chr7_+_33133547 1.90 ENSDART00000191967
si:ch211-194p6.7
si:ch211-194p6.7
chr1_+_12195700 1.89 ENSDART00000040307
tdrd7a
tudor domain containing 7 a
chr22_+_24446964 1.87 ENSDART00000166812
p3h2
prolyl 3-hydroxylase 2
chr4_+_76637548 1.87 ENSDART00000133799
ms4a17a.9
membrane-spanning 4-domains, subfamily A, member 17A.9
chr17_-_45386546 1.83 ENSDART00000182647
tmem206
transmembrane protein 206
chr16_+_9713850 1.83 ENSDART00000164103
ecm1b
extracellular matrix protein 1b
chr3_-_41292569 1.73 ENSDART00000111856
sdk1a
sidekick cell adhesion molecule 1a
chr3_+_3852614 1.69 ENSDART00000184334
ENSDART00000162313
si:ch73-338o16.4
si:ch73-338o16.4
chr17_-_45040813 1.68 ENSDART00000075514
entpd5a
ectonucleoside triphosphate diphosphohydrolase 5a
chr20_+_6493648 1.68 ENSDART00000099846
mep1b
meprin A, beta
chr19_-_46091497 1.66 ENSDART00000178772
ENSDART00000167255
ptdss1b
si:dkey-108k24.2
phosphatidylserine synthase 1b
si:dkey-108k24.2
chr14_+_33329761 1.65 ENSDART00000161138
sowahd
sosondowah ankyrin repeat domain family d
chr16_-_31717851 1.63 ENSDART00000169109
rbp5
retinol binding protein 1a, cellular
chr1_-_18585046 1.61 ENSDART00000147228
fam114a1
family with sequence similarity 114, member A1
chr12_-_30338779 1.61 ENSDART00000192511
vwa2
von Willebrand factor A domain containing 2
chr20_+_37294112 1.55 ENSDART00000076293
ENSDART00000140450
cx23
connexin 23
chr18_-_20444296 1.54 ENSDART00000132993
kif23
kinesin family member 23
chr2_-_15563194 1.53 ENSDART00000049589
col11a1b
collagen, type XI, alpha 1b
chr19_-_35596207 1.52 ENSDART00000136811
col8a2
collagen, type VIII, alpha 2
chr21_+_6397463 1.52 ENSDART00000136539
si:ch211-225g23.1
si:ch211-225g23.1
chr5_+_36895545 1.52 ENSDART00000135776
ENSDART00000147561
ENSDART00000133842
ENSDART00000051185
ENSDART00000141984
ENSDART00000136301
ENSDART00000142388
srsf7a
serine/arginine-rich splicing factor 7a
chr8_-_11067079 1.50 ENSDART00000181986
dennd2c
DENN/MADD domain containing 2C
chr23_-_43718067 1.50 ENSDART00000015777
abce1
ATP-binding cassette, sub-family E (OABP), member 1
chr25_+_32390794 1.46 ENSDART00000012600
galk2
galactokinase 2
chr21_-_22485847 1.45 ENSDART00000162860
myo5b
myosin VB
chr6_-_31364475 1.41 ENSDART00000145715
ENSDART00000134370
ak4
adenylate kinase 4
chr15_+_27387555 1.41 ENSDART00000018603
tbx4
T-box 4
chr9_-_27738110 1.39 ENSDART00000060347
crygs2
crystallin, gamma S2
chr3_-_3439150 1.39 ENSDART00000021286
A2ML1 (1 of many)
si:dkey-46g23.5
chr19_+_19761966 1.34 ENSDART00000163697
hoxa3a
homeobox A3a
chr8_+_25351863 1.31 ENSDART00000034092
dnase1l1l
deoxyribonuclease I-like 1-like
chr14_-_22015232 1.30 ENSDART00000137795
ssrp1a
structure specific recognition protein 1a
chr6_+_2048920 1.29 ENSDART00000153568
quo
quattro
chr14_-_30747686 1.27 ENSDART00000008373
fosl1a
FOS-like antigen 1a
chr14_-_41678749 1.27 ENSDART00000163039
fgfrl1b
fibroblast growth factor receptor like 1b
chr5_+_22393501 1.25 ENSDART00000185276
si:dkey-27p18.7
si:dkey-27p18.7
chr17_-_45387134 1.24 ENSDART00000010975
tmem206
transmembrane protein 206
chr1_+_58400409 1.23 ENSDART00000111526
si:ch73-59p9.2
si:ch73-59p9.2
chr8_+_41413919 1.21 ENSDART00000142590
si:ch211-152p23.2
si:ch211-152p23.2
chr7_-_3630019 1.21 ENSDART00000138164
ENSDART00000064277
si:dkey-192d15.3
si:dkey-192d15.3
chr25_-_27842654 1.18 ENSDART00000154852
ENSDART00000156906
asb15a
ankyrin repeat and SOCS box containing 15a
chr16_-_31718013 1.16 ENSDART00000190716
rbp5
retinol binding protein 1a, cellular
chr7_-_26924903 1.16 ENSDART00000124363
alx4a
ALX homeobox 4a
chr14_+_45970033 1.15 ENSDART00000047716
fermt3b
fermitin family member 3b
chr25_-_36263115 1.12 ENSDART00000143046
ENSDART00000139002
dus2
dihydrouridine synthase 2
chr7_-_24875421 1.09 ENSDART00000173920
adad2
adenosine deaminase domain containing 2
chr4_+_5193198 1.09 ENSDART00000067388
fgf23
fibroblast growth factor 23
chr13_-_36049008 1.09 ENSDART00000189978
lgmn
legumain
chr14_-_52433292 1.08 ENSDART00000164272
rest
RE1-silencing transcription factor
chr7_+_39444843 1.08 ENSDART00000143999
ENSDART00000173554
ENSDART00000173698
ENSDART00000173754
ENSDART00000144075
ENSDART00000138192
ENSDART00000145457
ENSDART00000141750
ENSDART00000103056
ENSDART00000142946
ENSDART00000173748
tnnt3b
troponin T type 3b (skeletal, fast)
chr3_-_43954971 1.07 ENSDART00000167159
ENSDART00000189315
ubfd1
ubiquitin family domain containing 1
chr6_+_18321627 1.06 ENSDART00000183107
ENSDART00000189715
card14
caspase recruitment domain family, member 14
chr6_+_32834007 1.04 ENSDART00000157353
cyldl
cylindromatosis (turban tumor syndrome), like
chr10_+_29770120 1.01 ENSDART00000100032
ENSDART00000193205
hyou1
hypoxia up-regulated 1
chr4_+_54864061 0.99 ENSDART00000157604
si:dkey-19c16.12
si:dkey-19c16.12
chr6_-_30689126 0.98 ENSDART00000065211
pars2
prolyl-tRNA synthetase 2, mitochondrial
chr4_+_18960914 0.98 ENSDART00000139730
impdh1b
IMP (inosine 5'-monophosphate) dehydrogenase 1b
chr23_-_38160024 0.98 ENSDART00000087112
pfdn4
prefoldin subunit 4
chr5_-_42883761 0.97 ENSDART00000167374
BX323596.2

chr2_+_2957515 0.97 ENSDART00000160715
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr15_-_31413984 0.94 ENSDART00000183896
ENSDART00000127547
or111-10
odorant receptor, family D, subfamily 111, member 10
chr4_+_63254033 0.94 ENSDART00000170121
si:ch211-258f1.3
si:ch211-258f1.3
chr2_+_413370 0.93 ENSDART00000122138
mylk4a
myosin light chain kinase family, member 4a
chr22_+_26263290 0.92 ENSDART00000184840
BX649315.1

chr17_-_2834764 0.92 ENSDART00000024027
bdkrb1
bradykinin receptor B1
chr2_-_27330181 0.91 ENSDART00000137053
tmx3a
thioredoxin related transmembrane protein 3a
chr2_-_9989919 0.89 ENSDART00000180213
ENSDART00000184369
imp3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr8_+_41048501 0.88 ENSDART00000123288
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr16_-_17188294 0.87 ENSDART00000165883
opn9
opsin 9
chr20_+_46897504 0.86 ENSDART00000158124
si:ch73-21k16.1
si:ch73-21k16.1
chr4_+_14971239 0.86 ENSDART00000005985
smo
smoothened, frizzled class receptor
chr9_+_27354653 0.85 ENSDART00000134134
tlr20.2
toll-like receptor 20, tandem duplicate 2
chr23_+_43718115 0.84 ENSDART00000149266
ENSDART00000149503
anapc10
anaphase promoting complex subunit 10

Network of associatons between targets according to the STRING database.

First level regulatory network of stat4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
1.9 13.0 GO:0001909 leukocyte mediated cytotoxicity(GO:0001909)
1.5 7.4 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
1.5 4.4 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468)
1.5 4.4 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
1.4 4.1 GO:0022009 central nervous system vasculogenesis(GO:0022009)
1.3 6.6 GO:0043011 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
1.2 6.2 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
1.1 4.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
1.0 5.2 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
1.0 3.1 GO:0045649 regulation of macrophage differentiation(GO:0045649)
1.0 4.0 GO:0060471 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.9 6.9 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.8 4.2 GO:0097272 ammonia homeostasis(GO:0097272)
0.8 4.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.7 3.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.7 3.4 GO:0071939 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.6 4.5 GO:0032570 response to progesterone(GO:0032570)
0.6 1.9 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.6 3.8 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.5 2.7 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.5 3.2 GO:0032218 riboflavin transport(GO:0032218)
0.5 3.3 GO:0060017 parathyroid gland development(GO:0060017)
0.5 3.7 GO:1990845 adaptive thermogenesis(GO:1990845)
0.4 2.7 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.4 0.9 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.4 2.9 GO:0071294 cellular response to zinc ion(GO:0071294)
0.4 2.4 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.4 1.2 GO:0033632 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.4 1.5 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.4 1.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785) negative regulation of cell maturation(GO:1903430)
0.3 4.1 GO:0050688 regulation of response to biotic stimulus(GO:0002831) regulation of defense response to virus(GO:0050688)
0.3 7.7 GO:0042102 positive regulation of T cell proliferation(GO:0042102)
0.3 3.4 GO:0034340 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.3 1.4 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.3 2.0 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.3 2.8 GO:0055062 phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.3 1.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.3 3.5 GO:0070527 platelet aggregation(GO:0070527)
0.3 5.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 0.9 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.2 1.5 GO:0040016 embryonic cleavage(GO:0040016)
0.2 2.2 GO:0001541 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.2 1.5 GO:0006012 galactose metabolic process(GO:0006012)
0.2 1.4 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.2 6.5 GO:0045332 phospholipid translocation(GO:0045332)
0.2 3.5 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.2 0.5 GO:0050968 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.2 1.9 GO:0030719 P granule organization(GO:0030719)
0.2 1.5 GO:0006415 translational termination(GO:0006415)
0.2 1.7 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.2 1.2 GO:0031179 peptide modification(GO:0031179)
0.1 1.9 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 2.1 GO:0060325 face morphogenesis(GO:0060325)
0.1 3.7 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 3.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.4 GO:0097676 histone H3-K4 trimethylation(GO:0080182) histone H3-K36 dimethylation(GO:0097676)
0.1 0.9 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 0.6 GO:1901207 regulation of heart looping(GO:1901207)
0.1 2.1 GO:0098754 detoxification(GO:0098754)
0.1 4.4 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 1.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 1.0 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 0.3 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 1.8 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.1 2.8 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.1 3.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 3.6 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 1.3 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 0.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 1.8 GO:0071456 cellular response to hypoxia(GO:0071456)
0.1 1.0 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.4 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
0.1 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 4.4 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.1 1.6 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 0.3 GO:0070459 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.1 6.3 GO:0001817 regulation of cytokine production(GO:0001817)
0.1 2.6 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.1 4.0 GO:0002685 regulation of leukocyte migration(GO:0002685)
0.1 0.8 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 1.9 GO:0061462 protein localization to lysosome(GO:0061462)
0.1 1.8 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.6 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 1.1 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.0 1.9 GO:0044236 multicellular organism metabolic process(GO:0044236)
0.0 1.9 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 2.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.0 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 2.5 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.2 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.9 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.7 GO:0010842 retina layer formation(GO:0010842)
0.0 0.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 7.9 GO:0009116 nucleoside metabolic process(GO:0009116)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 4.3 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.5 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 1.3 GO:0048332 mesoderm morphogenesis(GO:0048332)
0.0 0.8 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.0 1.3 GO:1902275 regulation of chromatin organization(GO:1902275)
0.0 2.2 GO:0016485 protein processing(GO:0016485)
0.0 0.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 1.1 GO:0006400 tRNA modification(GO:0006400)
0.0 0.0 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0 3.3 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 1.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 3.1 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.0 GO:0009229 thiamine diphosphate biosynthetic process(GO:0009229)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:1990909 Wnt signalosome(GO:1990909)
1.0 15.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.8 6.2 GO:0001772 immunological synapse(GO:0001772)
0.7 3.6 GO:0018444 translation release factor complex(GO:0018444)
0.5 1.5 GO:0005592 collagen type XI trimer(GO:0005592)
0.4 2.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 1.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 0.9 GO:0034457 Mpp10 complex(GO:0034457)
0.2 0.6 GO:0044316 cone cell pedicle(GO:0044316)
0.2 0.6 GO:0097541 axonemal basal plate(GO:0097541)
0.2 11.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 3.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.2 2.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 6.8 GO:0008305 integrin complex(GO:0008305)
0.1 1.3 GO:0035101 FACT complex(GO:0035101)
0.1 6.7 GO:0019814 immunoglobulin complex(GO:0019814)
0.1 1.0 GO:0016272 prefoldin complex(GO:0016272)
0.1 2.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 3.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 7.8 GO:0030055 cell-substrate junction(GO:0030055)
0.1 1.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.9 GO:0043186 P granule(GO:0043186)
0.0 2.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 6.4 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 5.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 4.1 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 7.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 4.0 GO:0005884 actin filament(GO:0005884)
0.0 4.1 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 2.0 GO:0005643 nuclear pore(GO:0005643)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 2.0 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.0 1.5 GO:0005871 kinesin complex(GO:0005871)
0.0 2.2 GO:0016459 myosin complex(GO:0016459)
0.0 1.6 GO:0005604 basement membrane(GO:0005604)
0.0 1.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.8 GO:0016342 catenin complex(GO:0016342)
0.0 21.6 GO:0005576 extracellular region(GO:0005576)
0.0 3.2 GO:0000785 chromatin(GO:0000785)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 6.9 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
1.2 6.2 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
1.2 3.5 GO:0070051 fibrinogen binding(GO:0070051)
1.1 4.5 GO:0070891 lipoteichoic acid binding(GO:0070891)
1.0 5.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.0 4.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.9 3.7 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.9 7.9 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.7 2.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.7 2.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.7 5.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.5 3.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.5 1.9 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.4 11.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.4 3.6 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.3 2.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.3 2.8 GO:0016918 retinal binding(GO:0016918)
0.3 5.5 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 3.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 2.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 4.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.2 3.4 GO:0030515 snoRNA binding(GO:0030515)
0.2 1.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 5.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 2.7 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.9 GO:0008142 oxysterol binding(GO:0008142)
0.1 2.6 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.2 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 1.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.3 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.9 GO:0016972 thiol oxidase activity(GO:0016972)
0.1 1.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 3.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.4 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.1 1.5 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.9 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 3.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.1 GO:0050700 CARD domain binding(GO:0050700)
0.1 1.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 1.7 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 1.1 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 1.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 4.4 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.1 0.7 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 1.9 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.7 GO:0004096 catalase activity(GO:0004096)
0.1 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.9 GO:0042805 actinin binding(GO:0042805)
0.1 0.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 3.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 4.2 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 1.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 5.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 4.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 12.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.8 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 6.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 4.3 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.5 GO:0005217 intracellular ligand-gated ion channel activity(GO:0005217) calcium-release channel activity(GO:0015278)
0.0 6.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.6 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 1.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.2 GO:0005178 integrin binding(GO:0005178)
0.0 5.3 GO:0042802 identical protein binding(GO:0042802)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 3.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 5.9 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 11.3 GO:0003779 actin binding(GO:0003779)
0.0 2.1 GO:0003774 motor activity(GO:0003774)
0.0 0.2 GO:0008061 chitin binding(GO:0008061)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 2.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 8.2 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 1.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0030975 thiamine diphosphokinase activity(GO:0004788) diphosphotransferase activity(GO:0016778) thiamine binding(GO:0030975)
0.0 10.5 GO:0008270 zinc ion binding(GO:0008270)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 2.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 3.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 3.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 2.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 4.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 3.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 2.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 5.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.1 PID FGF PATHWAY FGF signaling pathway
0.0 1.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 12.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.5 7.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.4 12.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 2.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 1.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 3.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 2.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 2.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.2 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 0.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.5 REACTOME KINESINS Genes involved in Kinesins
0.1 2.0 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 3.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.0 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 2.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 3.7 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 2.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 2.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.5 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production