Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for stat5a+stat5b

Z-value: 0.63

Motif logo

logo of

Transcription factors associated with stat5a+stat5b

Gene Symbol Gene ID Gene Info
stat5a
ENSDARG00000019392 signal transducer and activator of transcription 5a
stat5b
ENSDARG00000055588 signal transducer and activator of transcription 5b
stat5a
ENSDARG00000113871 signal transducer and activator of transcription 5a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
stat5bdr11_v1_chr12_-_13650344_13650472-0.398.9e-05Click!
stat5adr11_v1_chr3_+_17314997_173149970.112.9e-01Click!

Activity profile of stat5a+stat5b motif

Sorted Z-values of stat5a+stat5b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_37933983 4.79 ENSDART00000185364
scn4bb
sodium channel, voltage-gated, type IV, beta b
chr23_+_26017227 3.51 ENSDART00000002939
pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr19_-_32804535 3.51 ENSDART00000175613
ENSDART00000052098
nt5c1aa
5'-nucleotidase, cytosolic IAa
chr19_-_12648408 3.35 ENSDART00000103692
fam210aa
family with sequence similarity 210, member Aa
chr25_+_6186823 3.23 ENSDART00000153526
oaz2a
ornithine decarboxylase antizyme 2a
chr2_+_22659787 3.06 ENSDART00000043956
zgc:161973
zgc:161973
chr22_+_36914636 2.91 ENSDART00000150948
pimr205
Pim proto-oncogene, serine/threonine kinase, related 205
chr8_-_42624454 2.74 ENSDART00000075550
kazald3
Kazal-type serine peptidase inhibitor domain 3
chr21_-_38619305 2.54 ENSDART00000139178
slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr2_+_37140448 2.51 ENSDART00000045016
ENSDART00000142940
pex19
peroxisomal biogenesis factor 19
chr15_-_15449929 2.38 ENSDART00000101918
proca1
protein interacting with cyclin A1
chr12_-_314899 2.28 ENSDART00000066579
pts
6-pyruvoyltetrahydropterin synthase
chr20_+_10166297 2.26 ENSDART00000141877
kcnk10a
potassium channel, subfamily K, member 10a
chr2_-_51794472 2.25 ENSDART00000186652
BX908782.3

chr22_+_7480465 2.15 ENSDART00000034545
CELA1 (1 of many)
zgc:92745
chr16_+_34523515 2.10 ENSDART00000041007
stmn1b
stathmin 1b
chr15_-_32383529 2.02 ENSDART00000028349
c4
complement component 4
chr15_-_2857961 2.01 ENSDART00000033263
ankrd49
ankyrin repeat domain 49
chr2_-_49978227 2.00 ENSDART00000142835
hecw1b
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1b
chr25_-_27842654 1.98 ENSDART00000154852
ENSDART00000156906
asb15a
ankyrin repeat and SOCS box containing 15a
chr7_-_36358735 1.95 ENSDART00000188392
fto
fat mass and obesity associated
chr3_-_46818001 1.81 ENSDART00000166505
elavl3
ELAV like neuron-specific RNA binding protein 3
chr20_+_48754045 1.80 ENSDART00000062578
zgc:110348
zgc:110348
chr7_-_36358303 1.80 ENSDART00000130028
fto
fat mass and obesity associated
chr5_+_27137473 1.80 ENSDART00000181833
unc5db
unc-5 netrin receptor Db
chr12_+_22680115 1.78 ENSDART00000152879
ablim2
actin binding LIM protein family, member 2
chr15_-_32383340 1.78 ENSDART00000185632
c4
complement component 4
chr4_+_11479705 1.76 ENSDART00000019458
ENSDART00000150587
ENSDART00000139370
ENSDART00000135826
asb13a.1
ankyrin repeat and SOCS box containing 13a, tandem duplicate 1
chr7_+_58751504 1.74 ENSDART00000024185
zgc:56231
zgc:56231
chr3_-_46817838 1.70 ENSDART00000028610
elavl3
ELAV like neuron-specific RNA binding protein 3
chr18_+_6479963 1.70 ENSDART00000092752
ENSDART00000136333
wash1
WAS protein family homolog 1
chr12_-_46959990 1.65 ENSDART00000084557
lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr10_-_43568239 1.64 ENSDART00000131731
ENSDART00000097433
ENSDART00000131309
mef2ca
myocyte enhancer factor 2ca
chr2_+_7192966 1.62 ENSDART00000142735
si:ch211-13f8.1
si:ch211-13f8.1
chr19_+_25504645 1.59 ENSDART00000143292
col28a1a
collagen, type XXVIII, alpha 1a
chr20_+_46897504 1.58 ENSDART00000158124
si:ch73-21k16.1
si:ch73-21k16.1
chr7_-_11605185 1.54 ENSDART00000169291
ENSDART00000113904
stard5
StAR-related lipid transfer (START) domain containing 5
chr3_+_26905024 1.53 ENSDART00000077835
dexi
Dexi homolog (mouse)
chr6_+_16870004 1.51 ENSDART00000154794
pimr21
Pim proto-oncogene, serine/threonine kinase, related 21
chr1_-_7582859 1.51 ENSDART00000110696
mxb
myxovirus (influenza) resistance B
chr20_+_17581881 1.49 ENSDART00000182832
cdh2
cadherin 2, type 1, N-cadherin (neuronal)
chr10_-_24868581 1.49 ENSDART00000193055
CABZ01058107.1

chr13_-_49819027 1.45 ENSDART00000067824
b3galnt2
beta-1,3-N-acetylgalactosaminyltransferase 2
chr18_+_41772474 1.45 ENSDART00000097547
trpc6b
transient receptor potential cation channel, subfamily C, member 6b
chr3_+_54047342 1.42 ENSDART00000178486
olfm2a
olfactomedin 2a
chr25_+_33063762 1.39 ENSDART00000189974
tln2b
talin 2b
chr9_+_18572970 1.37 ENSDART00000114860
lacc1
laccase (multicopper oxidoreductase) domain containing 1
chr15_+_29088426 1.36 ENSDART00000187290
si:ch211-137a8.4
si:ch211-137a8.4
chr4_-_5863906 1.35 ENSDART00000169424
slc5a8
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr8_-_45838481 1.33 ENSDART00000148206
ENSDART00000170485
ogdha
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr13_+_6092135 1.33 ENSDART00000162738
fam120b
family with sequence similarity 120B
chr5_-_42883761 1.32 ENSDART00000167374
BX323596.2

chr18_+_17660402 1.32 ENSDART00000143475
cpne2
copine II
chr15_-_23485752 1.29 ENSDART00000152706
nlrx1
NLR family member X1
chr19_-_12648122 1.29 ENSDART00000151184
fam210aa
family with sequence similarity 210, member Aa
chr9_+_219124 1.29 ENSDART00000161484
map3k12
mitogen-activated protein kinase kinase kinase 12
chr19_+_24596324 1.28 ENSDART00000052420
si:dkeyp-92c9.2
si:dkeyp-92c9.2
chr22_-_16180467 1.24 ENSDART00000171331
ENSDART00000185607
vcam1b
vascular cell adhesion molecule 1b
chr5_-_4245186 1.23 ENSDART00000145912
si:ch211-283g2.3
si:ch211-283g2.3
chr8_-_46060685 1.21 ENSDART00000121902
pimr188
Pim proto-oncogene, serine/threonine kinase, related 188
chr20_+_37294112 1.19 ENSDART00000076293
ENSDART00000140450
cx23
connexin 23
chr11_-_17964525 1.18 ENSDART00000018948
cishb
cytokine inducible SH2-containing protein b
chr1_+_33322174 1.18 ENSDART00000140435
mxra5a
matrix-remodelling associated 5a
chr8_-_47212686 1.16 ENSDART00000040370
pimr189
Pim proto-oncogene, serine/threonine kinase, related 189
chr14_+_22132388 1.15 ENSDART00000109065
ccng1
cyclin G1
chr7_+_53254234 1.14 ENSDART00000169830
trip4
thyroid hormone receptor interactor 4
chr6_+_16895685 1.09 ENSDART00000154090
pimr28
Pim proto-oncogene, serine/threonine kinase, related 28
chr7_+_29009161 1.09 ENSDART00000166458
CR376738.1

chr7_-_38687431 1.09 ENSDART00000074490
aplnr2
apelin receptor 2
chr17_+_46864116 1.07 ENSDART00000156250
pimr27
Pim proto-oncogene, serine/threonine kinase, related 27
chr7_+_29890292 1.06 ENSDART00000170403
ENSDART00000168600
tln2a
talin 2a
chr19_+_15443063 1.02 ENSDART00000151732
lin28a
lin-28 homolog A (C. elegans)
chr2_-_42109575 1.01 ENSDART00000075551
adhfe1
alcohol dehydrogenase, iron containing, 1
chr22_-_9861531 1.01 ENSDART00000193197
si:dkey-253d23.2
si:dkey-253d23.2
chr10_+_36299541 0.99 ENSDART00000166138
or106-7
odorant receptor, family G, subfamily 106, member 7
chr24_+_13635387 0.99 ENSDART00000105997
trpa1b
transient receptor potential cation channel, subfamily A, member 1b
chr7_-_13362590 0.94 ENSDART00000091616
sdhaf2
succinate dehydrogenase complex assembly factor 2
chr4_-_57572054 0.93 ENSDART00000158610
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr13_-_25284716 0.93 ENSDART00000039828
vcla
vinculin a
chr2_-_3611960 0.92 ENSDART00000184579
pter
phosphotriesterase related
chr10_+_44700103 0.92 ENSDART00000165999
scarb1
scavenger receptor class B, member 1
chr13_-_9335891 0.92 ENSDART00000080637
BX901922.1

chr25_+_13620555 0.91 ENSDART00000163642
si:ch211-172l8.4
si:ch211-172l8.4
chr21_+_37090585 0.91 ENSDART00000182971
znf346
zinc finger protein 346
chr15_-_41290415 0.90 ENSDART00000152157
si:dkey-75b17.1
si:dkey-75b17.1
chr15_-_25039083 0.88 ENSDART00000154409
pimr190
Pim proto-oncogene, serine/threonine kinase, related 190
chr8_+_10920205 0.86 ENSDART00000179742
BX321886.1

chr15_-_31401361 0.84 ENSDART00000124360
or111-7
odorant receptor, family D, subfamily 111, member 7
chr17_+_12255642 0.83 ENSDART00000155175
pimr175
Pim proto-oncogene, serine/threonine kinase, related 175
chr4_+_34599803 0.83 ENSDART00000134088
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr20_-_54508650 0.82 ENSDART00000147642
CABZ01118770.1

chr12_+_46742805 0.80 ENSDART00000192236
plaub
plasminogen activator, urokinase b
chr7_+_17560808 0.76 ENSDART00000159699
ENSDART00000165724
ENSDART00000129017
ENSDART00000101955
nitr1b
novel immune-type receptor 1b
chr7_+_17303944 0.76 ENSDART00000163505
ENSDART00000162169
ENSDART00000161291
nitr9
novel immune-type receptor 9
chr4_-_57571688 0.76 ENSDART00000160179
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr17_-_43517542 0.74 ENSDART00000133665
mrpl35
mitochondrial ribosomal protein L35
chr16_+_25126935 0.73 ENSDART00000058945
zgc:92590
zgc:92590
chr7_+_33133547 0.72 ENSDART00000191967
si:ch211-194p6.7
si:ch211-194p6.7
chr16_-_52879741 0.69 ENSDART00000166470
TPPP
tubulin polymerization promoting protein
chr12_+_22404108 0.65 ENSDART00000153055
hdlbpb
high density lipoprotein binding protein b
chr6_-_16804001 0.63 ENSDART00000155398
pimr40
Pim proto-oncogene, serine/threonine kinase, related 40
chr17_+_6536152 0.62 ENSDART00000062952
ENSDART00000121789
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr16_+_34522977 0.62 ENSDART00000144069
paqr7b
progestin and adipoQ receptor family member VII, b
chr23_-_37432459 0.62 ENSDART00000188916
zmp:0000001088
zmp:0000001088
chr22_-_10774735 0.59 ENSDART00000081156
timm13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr17_-_46817295 0.55 ENSDART00000155904
pimr24
Pim proto-oncogene, serine/threonine kinase, related 24
chr15_-_29556757 0.55 ENSDART00000060049
hspa13
heat shock protein 70 family, member 13
chr6_-_17266221 0.54 ENSDART00000155448
pimr18
Pim proto-oncogene, serine/threonine kinase, related 18
chr6_-_17052116 0.51 ENSDART00000156825
pimr45
Pim proto-oncogene, serine/threonine kinase, related 45
chr2_+_44426609 0.48 ENSDART00000112711
ENSDART00000154188
kcnab1b
potassium voltage-gated channel, shaker-related subfamily, beta member 1 b
chr17_-_46933567 0.48 ENSDART00000157274
pimr25
Pim proto-oncogene, serine/threonine kinase, related 25
chr1_-_10647484 0.48 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
si:dkey-31e10.1
chr6_-_16735402 0.48 ENSDART00000154216
pimr44
Pim proto-oncogene, serine/threonine kinase, related 44
chr5_-_42071505 0.47 ENSDART00000137224
ENSDART00000193721
cxcl11.7
cenpv
chemokine (C-X-C motif) ligand 11, duplicate 7
centromere protein V
chr13_+_2861265 0.47 ENSDART00000170602
ENSDART00000171687
XPO5
si:ch211-233m11.2
chr15_-_25010400 0.46 ENSDART00000155236
si:ch211-198e20.10
si:ch211-198e20.10
chr24_+_13635108 0.44 ENSDART00000183008
trpa1b
transient receptor potential cation channel, subfamily A, member 1b
chr1_-_493218 0.43 ENSDART00000031635
ercc5
excision repair cross-complementation group 5
chr10_+_44699734 0.41 ENSDART00000167952
ENSDART00000158681
ENSDART00000190188
ENSDART00000168276
scarb1
scavenger receptor class B, member 1
chr17_-_6536466 0.36 ENSDART00000188735
cenpo
centromere protein O
chr25_-_30394746 0.35 ENSDART00000185346
si:ch211-93f2.1
si:ch211-93f2.1
chr1_-_23588996 0.35 ENSDART00000102600
lcorl
ligand dependent nuclear receptor corepressor-like
chr13_-_17464654 0.34 ENSDART00000140312
lrmda
leucine rich melanocyte differentiation associated
chr4_-_18595525 0.34 ENSDART00000049061
cdkn1ba
cyclin-dependent kinase inhibitor 1Ba
chr20_+_28803977 0.33 ENSDART00000153351
ENSDART00000038149
fntb
farnesyltransferase, CAAX box, beta
chr12_+_48480632 0.32 ENSDART00000158157
arhgap44
Rho GTPase activating protein 44
chr17_-_6536305 0.31 ENSDART00000154855
cenpo
centromere protein O
chr1_-_10647307 0.29 ENSDART00000103548
si:dkey-31e10.1
si:dkey-31e10.1
chr3_-_32541033 0.29 ENSDART00000151476
ENSDART00000055324
rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr6_+_41503854 0.29 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cish
cytokine inducible SH2-containing protein
chr3_-_26904774 0.29 ENSDART00000103690
clec16a
C-type lectin domain containing 16A
chr8_+_25959940 0.28 ENSDART00000143011
ENSDART00000140626
si:dkey-72l14.4
si:dkey-72l14.4
chr17_-_24439672 0.27 ENSDART00000155020
wdpcp
WD repeat containing planar cell polarity effector
chr23_-_1571682 0.26 ENSDART00000013635
fbxo30b
F-box protein 30b
chr11_+_36409457 0.26 ENSDART00000077641
cyb561d1
cytochrome b561 family, member D1
chr3_-_6608342 0.25 ENSDART00000161188
si:ch73-59f11.3
si:ch73-59f11.3
chr7_+_65813301 0.24 ENSDART00000187449
ENSDART00000179834
ENSDART00000082740
ENSDART00000178627
tead1b
TEA domain family member 1b
chr12_-_23365737 0.24 ENSDART00000170376
mpp7a
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr15_-_6966221 0.23 ENSDART00000165487
ENSDART00000027657
mrps22
mitochondrial ribosomal protein S22
chr8_+_247163 0.23 ENSDART00000122378
cep120
centrosomal protein 120
chr20_+_52458765 0.22 ENSDART00000057980
tsta3
tissue specific transplantation antigen P35B
chr20_+_28803642 0.22 ENSDART00000188526
fntb
farnesyltransferase, CAAX box, beta
chr21_-_27010796 0.21 ENSDART00000065398
ENSDART00000144342
ENSDART00000126542
ppp1r14ba
protein phosphatase 1, regulatory (inhibitor) subunit 14Ba
chr4_+_13586455 0.21 ENSDART00000187230
tnpo3
transportin 3
chr4_-_49952636 0.18 ENSDART00000157941
si:dkey-156k2.3
si:dkey-156k2.3
chr14_-_6987649 0.16 ENSDART00000060990
eif4ebp3l
eukaryotic translation initiation factor 4E binding protein 3, like
chr18_-_20444296 0.15 ENSDART00000132993
kif23
kinesin family member 23
chr1_+_57040472 0.15 ENSDART00000181365
si:ch211-1f22.16
si:ch211-1f22.16
chr11_+_13024002 0.13 ENSDART00000104113
btf3l4
basic transcription factor 3-like 4
chr15_+_2857556 0.10 ENSDART00000157758
mre11a
MRE11 homolog A, double strand break repair nuclease
chr24_-_18477672 0.08 ENSDART00000126928
ENSDART00000158393
si:dkey-73n8.3
si:dkey-73n8.3
chr15_-_25083200 0.07 ENSDART00000156053
pimr191
Pim proto-oncogene, serine/threonine kinase, related 191
chr21_+_22400951 0.07 ENSDART00000134592
lmbrd2b
LMBR1 domain containing 2b
chr11_+_30314885 0.06 ENSDART00000187418
ENSDART00000123244
ugt1b2
UDP glucuronosyltransferase 1 family, polypeptide B2
chr4_-_685412 0.04 ENSDART00000168167
rtcb
RNA 2',3'-cyclic phosphate and 5'-OH ligase
chr17_+_11372531 0.04 ENSDART00000130975
ENSDART00000149366
timm9
translocase of inner mitochondrial membrane 9 homolog

Network of associatons between targets according to the STRING database.

First level regulatory network of stat5a+stat5b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0042245 RNA repair(GO:0042245)
0.6 2.5 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.5 1.6 GO:0036076 ligamentous ossification(GO:0036076)
0.5 2.5 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.5 1.5 GO:0021577 hindbrain structural organization(GO:0021577) dorsal fin morphogenesis(GO:0035142) cell motility involved in somitogenic axis elongation(GO:0090247) cell migration involved in somitogenic axis elongation(GO:0090248)
0.5 1.4 GO:0050968 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.4 1.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.3 3.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 2.0 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.2 2.3 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 3.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 0.9 GO:0097032 mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.2 2.4 GO:0050482 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.2 1.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.2 0.6 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.2 0.9 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.1 0.4 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.5 GO:0018343 protein farnesylation(GO:0018343)
0.1 3.2 GO:0006595 polyamine metabolic process(GO:0006595)
0.1 0.5 GO:1901380 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 0.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 2.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 1.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 1.5 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 1.1 GO:0061055 myotome development(GO:0061055)
0.1 1.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.8 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.2 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.1 1.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 1.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.3 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 1.6 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 1.3 GO:0015908 fatty acid transport(GO:0015908)
0.0 2.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 1.3 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 1.5 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.2 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.0 1.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 3.8 GO:0006956 complement activation(GO:0006956)
0.0 13.3 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.5 GO:0042026 protein refolding(GO:0042026)
0.0 0.6 GO:0001556 oocyte maturation(GO:0001556)
0.0 1.1 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.0 1.6 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.3 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.8 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.3 GO:0032418 lysosome localization(GO:0032418)
0.0 3.0 GO:0040008 regulation of growth(GO:0040008)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 3.5 GO:0050767 regulation of neurogenesis(GO:0050767)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.3 2.7 GO:0005614 interstitial matrix(GO:0005614)
0.3 1.7 GO:0071203 WASH complex(GO:0071203)
0.3 1.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 0.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 0.7 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.1 0.5 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 1.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.5 GO:0014704 intercalated disc(GO:0014704)
0.1 0.3 GO:0097541 axonemal basal plate(GO:0097541)
0.1 1.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 2.5 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 1.3 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 3.8 GO:0016607 nuclear speck(GO:0016607)
0.0 1.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0005844 polysome(GO:0005844)
0.0 2.4 GO:0005925 focal adhesion(GO:0005925)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.9 GO:0042383 sarcolemma(GO:0042383)
0.0 1.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 3.8 GO:0030424 axon(GO:0030424)
0.0 1.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 14.3 GO:0005739 mitochondrion(GO:0005739)
0.0 1.5 GO:0034703 cation channel complex(GO:0034703)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.8 GO:1990931 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.8 3.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.5 2.5 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.4 1.7 GO:0004427 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.3 1.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 1.5 GO:0032052 bile acid binding(GO:0032052)
0.3 2.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.3 3.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 2.5 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.2 1.1 GO:0060182 apelin receptor activity(GO:0060182)
0.2 1.8 GO:0005042 netrin receptor activity(GO:0005042)
0.2 1.0 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 3.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 1.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 0.6 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 1.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.5 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 1.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 2.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 2.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 2.3 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 1.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 1.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 1.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 2.4 GO:0005178 integrin binding(GO:0005178)
0.0 1.3 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 1.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.7 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 1.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.5 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 1.4 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 1.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.5 GO:0045296 cadherin binding(GO:0045296)
0.0 14.3 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 3.6 GO:0015631 tubulin binding(GO:0015631)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.1 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 2.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 3.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.0 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.4 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import