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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for tal1

Z-value: 2.06

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Transcription factors associated with tal1

Gene Symbol Gene ID Gene Info
tal1
ENSDARG00000019930 T-cell acute lymphocytic leukemia 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tal1dr11_v1_chr22_+_16535575_16535575-0.742.6e-17Click!

Activity profile of tal1 motif

Sorted Z-values of tal1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_61181018 35.05 ENSDART00000187970
pvalb4
parvalbumin 4
chr12_+_13256415 31.84 ENSDART00000144542
atp2a1l
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr8_-_1051438 26.67 ENSDART00000067093
ENSDART00000170737
smyd1b
SET and MYND domain containing 1b
chr7_+_39389273 25.74 ENSDART00000191298
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr22_+_20720808 25.03 ENSDART00000171321
si:dkey-211f22.5
si:dkey-211f22.5
chr3_-_61203203 23.80 ENSDART00000171787
pvalb1
parvalbumin 1
chr18_+_5547185 23.53 ENSDART00000193977
nnt2
nicotinamide nucleotide transhydrogenase 2
chr9_+_307863 23.10 ENSDART00000163474
stac3
SH3 and cysteine rich domain 3
chr3_-_3209432 21.95 ENSDART00000140635
si:ch211-229i14.2
si:ch211-229i14.2
chr3_-_1190132 21.76 ENSDART00000149709
smdt1a
single-pass membrane protein with aspartate-rich tail 1a
chr18_+_54354 19.38 ENSDART00000097163
zgc:158482
zgc:158482
chr11_-_45171139 16.93 ENSDART00000167036
ENSDART00000161712
ENSDART00000158156
syngr2b
synaptogyrin 2b
chr23_+_44614056 16.35 ENSDART00000188379
eno3
enolase 3, (beta, muscle)
chr15_-_551177 13.99 ENSDART00000066774
ENSDART00000154617
tagln
transgelin
chr3_+_2669813 13.85 ENSDART00000014205
CR388047.1

chr2_-_44255537 13.69 ENSDART00000011188
ENSDART00000093298
atp1a2a
ATPase Na+/K+ transporting subunit alpha 2
chr21_-_551014 13.55 ENSDART00000099252
vimr1
vimentin-related 1
chr5_-_7829657 13.42 ENSDART00000158374
pdlim5a
PDZ and LIM domain 5a
chr5_+_338154 13.30 ENSDART00000191743
rnf170
ring finger protein 170
chr18_+_5454341 13.21 ENSDART00000192649
dtwd1
DTW domain containing 1
chr7_+_31891110 12.84 ENSDART00000173883
mybpc3
myosin binding protein C, cardiac
chr3_+_58833306 12.61 ENSDART00000113223
igl1c3
immunoglobulin light 1 constant 3
chr22_-_37738203 12.54 ENSDART00000143190
acap2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr17_+_53311618 11.91 ENSDART00000166517
asb2b
ankyrin repeat and SOCS box containing 2b
chr20_+_33981946 11.86 ENSDART00000131775
si:dkey-51e6.1
si:dkey-51e6.1
chr16_+_47308856 11.82 ENSDART00000170103
col28a1b
collagen, type XXVIII, alpha 1b
chr13_+_51981764 11.81 ENSDART00000160698
klhdc3
kelch domain containing 3
chr1_+_50293938 11.75 ENSDART00000084184
aimp1
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
chr1_-_206208 11.71 ENSDART00000060968
adprhl1
ADP-ribosylhydrolase like 1
chr24_+_42074143 11.59 ENSDART00000170514
top1mt
DNA topoisomerase I mitochondrial
chr5_+_431994 11.36 ENSDART00000181692
ENSDART00000170350
thap1
THAP domain containing, apoptosis associated protein 1
chr14_-_9281232 11.31 ENSDART00000054693
asb12b
ankyrin repeat and SOCS box-containing 12b
chr25_-_37501371 11.24 ENSDART00000160498
CABZ01088346.1

chr19_+_48117995 11.21 ENSDART00000170865
nme2b.1
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
chr23_+_19790962 11.16 ENSDART00000142228
flna
filamin A, alpha (actin binding protein 280)
chr20_-_54377933 11.13 ENSDART00000182664
entpd5b
ectonucleoside triphosphate diphosphohydrolase 5b
chr21_-_217589 10.98 ENSDART00000185017
CZQB01146713.1

chr9_+_33220342 10.90 ENSDART00000100893
ENSDART00000113451
si:ch211-125e6.13
si:ch211-125e6.13
chr9_-_105135 10.55 ENSDART00000180126
FQ377903.3

chr25_+_3318192 10.51 ENSDART00000146154
slc25a3b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr13_-_438705 10.35 ENSDART00000082142
CU570800.1

chr9_+_32178050 10.04 ENSDART00000169526
coq10b
coenzyme Q10B
chr17_-_868004 10.02 ENSDART00000112803
wdr20a
WD repeat domain 20a
chr4_+_77943184 9.94 ENSDART00000159094
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr17_+_135590 9.65 ENSDART00000166339
klhdc2
kelch domain containing 2
chr4_-_16354292 9.62 ENSDART00000139919
lum
lumican
chr9_+_44994214 9.55 ENSDART00000141434
retsatl
retinol saturase (all-trans-retinol 13,14-reductase) like
chr17_-_2584423 9.02 ENSDART00000013506
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr22_+_18469004 8.91 ENSDART00000061430
cilp2
cartilage intermediate layer protein 2
chr6_-_13206255 8.89 ENSDART00000065373
eef1b2
eukaryotic translation elongation factor 1 beta 2
chr10_+_40633990 8.88 ENSDART00000190489
ENSDART00000139474
si:ch211-238p8.31
si:ch211-238p8.31
chr3_+_1209006 8.80 ENSDART00000158633
poldip3
polymerase (DNA-directed), delta interacting protein 3
chr4_-_64703 8.64 ENSDART00000167851
CU856344.1

chr7_-_30127082 8.59 ENSDART00000173749
alpk3b
alpha-kinase 3b
chr1_-_513762 8.58 ENSDART00000148162
ENSDART00000144606
trmt10c
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr17_-_2595736 8.57 ENSDART00000128797
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr17_+_53156530 8.50 ENSDART00000126277
ENSDART00000156774
dph6
diphthamine biosynthesis 6
chr17_+_132555 8.40 ENSDART00000158159
zgc:77287
zgc:77287
chr5_-_72376973 8.32 ENSDART00000164969
CABZ01100198.1

chr17_-_2573021 8.29 ENSDART00000074181
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr17_+_53311243 8.14 ENSDART00000160241
ENSDART00000160009
ENSDART00000162239
asb2b
ankyrin repeat and SOCS box containing 2b
chr25_-_18470695 8.00 ENSDART00000034377
cpa5
carboxypeptidase A5
chr23_-_9925568 7.89 ENSDART00000081268
si:ch211-220i18.4
si:ch211-220i18.4
chr16_+_54588930 7.88 ENSDART00000159174
dennd4b
DENN/MADD domain containing 4B
chr3_-_5413018 7.83 ENSDART00000063138
vmo1a
vitelline membrane outer layer 1 homolog a
chr18_-_11729 7.75 ENSDART00000159781
WHAMM
WAS protein homolog associated with actin, golgi membranes and microtubules
chr11_-_1392468 7.67 ENSDART00000004423
iars
isoleucyl-tRNA synthetase
chr18_-_46010 7.58 ENSDART00000052641
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr24_+_26276805 7.56 ENSDART00000089749
adipoqa
adiponectin, C1Q and collagen domain containing, a
chr6_+_40629066 7.39 ENSDART00000103757
slc6a11a
solute carrier family 6 (neurotransmitter transporter), member 11a
chr9_+_33217243 7.28 ENSDART00000053061
si:ch211-125e6.12
si:ch211-125e6.12
chr13_-_36581875 7.26 ENSDART00000113204
lgals3a
lectin, galactoside binding soluble 3a
chr20_+_2460864 7.23 ENSDART00000131642
akap7
A kinase (PRKA) anchor protein 7
chr1_-_52494122 7.14 ENSDART00000131407
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr9_+_51225345 7.08 ENSDART00000132896
fap
fibroblast activation protein, alpha
chr11_+_42587900 7.07 ENSDART00000167529
asb14a
ankyrin repeat and SOCS box containing 14a
chr19_-_27588842 7.03 ENSDART00000121643
si:dkeyp-46h3.2
si:dkeyp-46h3.2
chr17_-_2590222 6.97 ENSDART00000185711
CR759892.1

chr21_-_45382112 6.90 ENSDART00000151029
ENSDART00000151335
ENSDART00000151687
ENSDART00000075438
cdkn2aipnl
CDKN2A interacting protein N-terminal like
chr9_-_23747264 6.79 ENSDART00000141461
ENSDART00000010311
ndufa10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10
chr24_+_42132962 6.75 ENSDART00000187739
wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr22_-_10541372 6.71 ENSDART00000179708
si:dkey-42i9.4
si:dkey-42i9.4
chr3_-_1388936 6.71 ENSDART00000171278
ddx47
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr1_-_59232267 6.69 ENSDART00000169658
ENSDART00000163257
akap8l
A kinase (PRKA) anchor protein 8-like
chr21_-_30293224 6.64 ENSDART00000101051
slbp2
stem-loop binding protein 2
chr17_+_20607487 6.62 ENSDART00000154123
si:ch73-288o11.5
si:ch73-288o11.5
chr21_+_10577527 6.59 ENSDART00000165070
ENSDART00000127963
ccbe1
collagen and calcium binding EGF domains 1
chr24_-_6029314 6.58 ENSDART00000136155
ftr60
finTRIM family, member 60
chr7_-_6346859 6.56 ENSDART00000172913
si:ch73-368j24.11
si:ch73-368j24.11
chr3_-_15154871 6.42 ENSDART00000147704
si:dkey-282h22.5
si:dkey-282h22.5
chr1_+_2260407 6.28 ENSDART00000058876
kpnb3
karyopherin (importin) beta 3
chr5_+_25762271 6.27 ENSDART00000181323
tmem2
transmembrane protein 2
chr12_-_656540 6.01 ENSDART00000172651
sult2st2
sulfotransferase family 2, cytosolic sulfotransferase 2
chr17_-_2578026 5.96 ENSDART00000065821
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr3_+_3519607 5.94 ENSDART00000150922
cdc42ep1b
CDC42 effector protein (Rho GTPase binding) 1b
chr22_-_26353916 5.80 ENSDART00000077958
capn2b
calpain 2, (m/II) large subunit b
chr17_+_584369 5.67 ENSDART00000165143
C14orf28
chromosome 14 open reading frame 28
chr7_-_6470431 5.62 ENSDART00000081359
zgc:110425
zgc:110425
chr14_-_17563773 5.60 ENSDART00000082667
fgfrl1a
fibroblast growth factor receptor like 1a
chr5_+_36895860 5.59 ENSDART00000134493
srsf7a
serine/arginine-rich splicing factor 7a
chr6_+_59176470 5.59 ENSDART00000161720
shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chr17_-_22001303 5.55 ENSDART00000122190
slc22a7b.2
solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 2
chr7_-_27033080 5.53 ENSDART00000173516
nucb2a
nucleobindin 2a
chr12_-_48168135 5.50 ENSDART00000186624
pald1a
phosphatase domain containing, paladin 1a
chr3_+_1179601 5.50 ENSDART00000173378
triobpb
TRIO and F-actin binding protein b
chr16_+_9495583 5.49 ENSDART00000150750
ENSDART00000150457
pimr208
Pim proto-oncogene, serine/threonine kinase, related 208
chr3_+_5504990 5.47 ENSDART00000143626
si:ch73-264i18.2
si:ch73-264i18.2
chr19_-_25519612 5.40 ENSDART00000133150
C1GALT1 (1 of many)
si:dkey-202e17.1
chr15_+_47525073 5.37 ENSDART00000067583
sidt2
SID1 transmembrane family, member 2
chr20_+_2281933 5.36 ENSDART00000137579
si:ch73-18b11.2
si:ch73-18b11.2
chr11_+_27364338 5.32 ENSDART00000186759
fbln2
fibulin 2
chr20_-_49729446 5.29 ENSDART00000111089
filip1b
filamin A interacting protein 1b
chr3_+_3545825 5.27 ENSDART00000109060
CR589947.1

chr3_+_726000 5.26 ENSDART00000158510
dicp1.17
diverse immunoglobulin domain-containing protein 1.17
chr3_+_54581987 5.15 ENSDART00000018071
eif3g
eukaryotic translation initiation factor 3, subunit G
chr17_+_53439606 5.03 ENSDART00000154946
si:zfos-1714f5.3
si:zfos-1714f5.3
chr4_+_5249494 4.98 ENSDART00000150391
si:ch211-214j24.14
si:ch211-214j24.14
chr11_+_37909654 4.96 ENSDART00000172211
si:ch211-112f3.4
si:ch211-112f3.4
chr13_+_669177 4.96 ENSDART00000190085
CU462915.1

chr25_-_36369057 4.84 ENSDART00000064400
si:ch211-113a14.24
si:ch211-113a14.24
chr17_-_681142 4.83 ENSDART00000165583
soul3
heme-binding protein soul3
chr11_-_44647286 4.83 ENSDART00000169329
ENSDART00000158939
tomm20b
translocase of outer mitochondrial membrane 20b
chr3_-_41715690 4.83 ENSDART00000184703
BX324110.1

chr7_+_1467863 4.73 ENSDART00000173433
emc4
ER membrane protein complex subunit 4
chr25_+_37290206 4.71 ENSDART00000086474
si:dkey-234i14.12
si:dkey-234i14.12
chr25_+_15933411 4.70 ENSDART00000191581
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr19_-_3783141 4.67 ENSDART00000162260
btr19
bloodthirsty-related gene family, member 19
chr10_+_40629616 4.65 ENSDART00000147476
CR396590.9

chr5_-_15692030 4.64 ENSDART00000099545
CR384085.1

chr15_-_34051457 4.63 ENSDART00000189764
VWDE
si:dkey-30e9.7
chr25_+_37289088 4.58 ENSDART00000073438
si:dkey-234i14.9
si:dkey-234i14.9
chr2_-_37888429 4.53 ENSDART00000183277
mbl2
mannose binding lectin 2
chr3_-_3939785 4.52 ENSDART00000049593
unm_sa1506
un-named sa1506
chr3_-_34098731 4.51 ENSDART00000150999
ighv5-3
immunoglobulin heavy variable 5-3
chr3_+_17537352 4.51 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr24_+_35827766 4.50 ENSDART00000144700
si:dkeyp-7a3.1
si:dkeyp-7a3.1
chr19_-_81851 4.49 ENSDART00000172319
hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr7_-_6415991 4.45 ENSDART00000173349
CU457819.3
Histone H3.2
chr2_+_19633493 4.43 ENSDART00000147989
pimr54
Pim proto-oncogene, serine/threonine kinase, related 54
chr3_-_34074806 4.43 ENSDART00000151415
ighv8-1
immunoglobulin heavy variable 8-1
chr10_-_40536963 4.42 ENSDART00000184052
ENSDART00000132523
taar18e
trace amine associated receptor 18e
chr3_+_3598555 4.41 ENSDART00000191152
CR589947.3

chr11_+_27364059 4.37 ENSDART00000172883
fbln2
fibulin 2
chr7_+_5964296 4.36 ENSDART00000173380
si:dkey-23a13.17
si:dkey-23a13.17
chr10_-_8294965 4.33 ENSDART00000167380
plpp1a
phospholipid phosphatase 1a
chr12_+_33433882 4.32 ENSDART00000185053
fasn
fatty acid synthase
chr5_+_37785152 4.28 ENSDART00000053511
ENSDART00000189812
myo1ca
myosin Ic, paralog a
chr12_-_48960308 4.26 ENSDART00000176247
CABZ01112647.1

chr23_-_44848961 4.24 ENSDART00000136839
wu:fb72h05
wu:fb72h05
chr1_-_53880639 4.19 ENSDART00000010543
ltv1
LTV1 ribosome biogenesis factor
chr1_-_53468160 4.16 ENSDART00000143349
zgc:66455
zgc:66455
chr15_+_28368823 4.16 ENSDART00000142298
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr1_+_57235896 4.12 ENSDART00000152621
si:dkey-27j5.7
si:dkey-27j5.7
chr24_+_5789582 4.09 ENSDART00000141504
BX470065.1

chr25_-_35153985 4.06 ENSDART00000154851
zgc:153405
zgc:153405
chr1_-_55263736 4.06 ENSDART00000152504
ENSDART00000152687
si:ch211-286b5.4
si:ch211-286b5.4
chr15_-_7598294 4.04 ENSDART00000165898
gbe1b
glucan (1,4-alpha-), branching enzyme 1b
chr1_-_59141715 4.03 ENSDART00000164941
ENSDART00000138870
si:ch1073-110a20.1
si:ch1073-110a20.1
chr8_-_1219815 4.03 ENSDART00000016800
ENSDART00000149969
znf367
zinc finger protein 367
chr3_-_10970502 3.98 ENSDART00000127500
CR382337.1

chr3_-_45848043 3.93 ENSDART00000055132
igfals
insulin-like growth factor binding protein, acid labile subunit
chr10_+_40737540 3.93 ENSDART00000125577
taar19a
trace amine associated receptor 19a
chr15_-_4485828 3.91 ENSDART00000062868
tfdp2
transcription factor Dp-2
chr7_+_33132074 3.90 ENSDART00000073554
zgc:153219
zgc:153219
chr8_-_27687095 3.90 ENSDART00000086946
mov10b.1
Moloney leukemia virus 10b, tandem duplicate 1
chr3_-_2613990 3.89 ENSDART00000137102
si:dkey-217f16.6
si:dkey-217f16.6
chr23_-_40895168 3.87 ENSDART00000061037
si:dkey-194e6.1
si:dkey-194e6.1
chr4_+_2267641 3.85 ENSDART00000165503
si:ch73-89b15.3
si:ch73-89b15.3
chr3_-_32590164 3.85 ENSDART00000151151
tspan4b
tetraspanin 4b
chr10_+_26896142 3.83 ENSDART00000188225
ehbp1l1b
EH domain binding protein 1-like 1b
chr7_+_6317866 3.82 ENSDART00000173397
si:ch211-220f21.3
si:ch211-220f21.3
chr1_-_55118745 3.81 ENSDART00000133915
sertad2a
SERTA domain containing 2a
chr25_+_1732838 3.80 ENSDART00000159555
ENSDART00000168161
FBLN1
fibulin 1
chr21_+_5531138 3.78 ENSDART00000163825
ly6m6
lymphocyte antigen 6 family member M6
chr16_+_32029090 3.76 ENSDART00000041054
tmc4
transmembrane channel-like 4
chr25_-_36263115 3.75 ENSDART00000143046
ENSDART00000139002
dus2
dihydrouridine synthase 2
chr13_-_133520 3.74 ENSDART00000180874
FO904997.1

chr25_+_37340722 3.72 ENSDART00000137025
pamr1
peptidase domain containing associated with muscle regeneration 1
chr5_+_7564644 3.71 ENSDART00000192173
CABZ01039096.1

chr24_-_26310854 3.71 ENSDART00000080113
apodb
apolipoprotein Db
chr7_+_35229805 3.68 ENSDART00000173911
tppp3
tubulin polymerization-promoting protein family member 3
chr14_+_9432627 3.68 ENSDART00000042727
si:dkeyp-86f7.4
si:dkeyp-86f7.4
chr23_+_1349277 3.68 ENSDART00000173133
ENSDART00000179877
utrn
utrophin
chr6_-_35439406 3.68 ENSDART00000073784
rgs5a
regulator of G protein signaling 5a
chr3_-_61592417 3.67 ENSDART00000155082
nptx2a
neuronal pentraxin 2a
chr5_+_28857969 3.66 ENSDART00000149850
si:ch211-186e20.2
si:ch211-186e20.2
chr12_-_49166761 3.63 ENSDART00000189407
acadsb
acyl-CoA dehydrogenase short/branched chain
chr10_+_406146 3.63 ENSDART00000145124
dact3a
dishevelled-binding antagonist of beta-catenin 3a
chr3_-_34037064 3.63 ENSDART00000151716
ighv9-4
immunoglobulin heavy variable 9-4
chr3_-_2623176 3.62 ENSDART00000179792
ENSDART00000123512
si:dkey-217f16.6
si:dkey-217f16.6
chr1_+_55703120 3.61 ENSDART00000141089
adgre6
adhesion G protein-coupled receptor E6
chr7_-_8470860 3.58 ENSDART00000172793
loc564481
hypothetical protein LOC564481
chr22_+_5971404 3.55 ENSDART00000122153
BX322587.1

chr1_+_277731 3.54 ENSDART00000133431
cenpe
centromere protein E
chr25_-_36261836 3.53 ENSDART00000179411
dus2
dihydrouridine synthase 2
chr5_+_41322783 3.53 ENSDART00000097546
arid3c
AT rich interactive domain 3C (BRIGHT-like)
chr14_+_17382803 3.53 ENSDART00000040383
si:ch211-255i20.3
si:ch211-255i20.3
chr4_+_8638622 3.53 ENSDART00000186829
wnt5b
wingless-type MMTV integration site family, member 5b
chr13_-_301309 3.50 ENSDART00000131747
chs1
chitin synthase 1
chr22_+_8272393 3.46 ENSDART00000121602
CABZ01077220.1

Network of associatons between targets according to the STRING database.

First level regulatory network of tal1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 23.5 GO:0006740 NADPH regeneration(GO:0006740)
4.6 23.1 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
4.6 13.7 GO:0065001 specification of axis polarity(GO:0065001)
4.0 11.9 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
3.9 11.7 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
2.6 12.8 GO:0003210 cardiac atrium formation(GO:0003210)
2.5 7.6 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
2.4 26.7 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
2.3 18.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
1.9 31.9 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
1.9 5.6 GO:0006565 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
1.8 8.9 GO:0090646 mitochondrial tRNA processing(GO:0090646)
1.8 31.7 GO:0016584 nucleosome positioning(GO:0016584)
1.5 7.3 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
1.4 8.5 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
1.0 9.9 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
1.0 4.8 GO:0051031 tRNA transport(GO:0051031)
0.9 17.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.9 6.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) embryonic cleavage(GO:0040016)
0.9 6.6 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.9 2.8 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.8 2.5 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.8 4.0 GO:1990592 IRE1-mediated unfolded protein response(GO:0036498) negative regulation of response to endoplasmic reticulum stress(GO:1903573) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.8 3.9 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.8 4.5 GO:0042745 temperature homeostasis(GO:0001659) circadian sleep/wake cycle process(GO:0022410) circadian sleep/wake cycle(GO:0042745) regulation of transmission of nerve impulse(GO:0051969)
0.7 20.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.7 3.5 GO:1904105 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.7 11.2 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.7 3.5 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.7 5.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.7 11.6 GO:0006265 DNA topological change(GO:0006265)
0.7 2.0 GO:0042421 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.7 3.3 GO:0098535 de novo centriole assembly(GO:0098535)
0.7 11.1 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.6 2.4 GO:0032530 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.6 25.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.6 5.9 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.6 2.3 GO:0042148 strand invasion(GO:0042148)
0.6 1.7 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.6 5.5 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.5 2.2 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.5 28.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.5 7.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.5 10.0 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.5 7.5 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.5 2.9 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.5 5.6 GO:0021592 fourth ventricle development(GO:0021592)
0.5 4.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.5 10.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.4 3.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.4 2.0 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.4 2.4 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.4 2.7 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.4 8.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 6.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.4 2.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3 10.1 GO:0055013 cardiac muscle cell development(GO:0055013)
0.3 2.7 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.3 2.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797) regulation of stem cell proliferation(GO:0072091)
0.3 2.3 GO:0098773 skin epidermis development(GO:0098773)
0.3 4.4 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.3 1.5 GO:0033292 T-tubule organization(GO:0033292)
0.3 1.8 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.3 1.5 GO:0051972 regulation of telomerase activity(GO:0051972)
0.3 3.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 2.0 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.3 5.3 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.3 0.5 GO:0010459 negative regulation of heart rate(GO:0010459)
0.3 0.8 GO:0015889 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.3 3.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 20.5 GO:0006400 tRNA modification(GO:0006400)
0.2 9.6 GO:0030199 collagen fibril organization(GO:0030199)
0.2 1.0 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.2 1.7 GO:0007141 male meiosis I(GO:0007141)
0.2 1.8 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 2.3 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.2 6.0 GO:0051923 sulfation(GO:0051923)
0.2 2.9 GO:0030325 adrenal gland development(GO:0030325)
0.2 2.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.2 5.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.2 3.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 1.6 GO:0007197 regulation of smooth muscle contraction(GO:0006940) adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2 0.5 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.2 0.7 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.2 3.8 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2 1.0 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.1 6.0 GO:0002548 monocyte chemotaxis(GO:0002548)
0.1 3.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 4.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 8.9 GO:0006414 translational elongation(GO:0006414)
0.1 3.1 GO:0048570 notochord morphogenesis(GO:0048570)
0.1 4.7 GO:0002377 immunoglobulin production(GO:0002377)
0.1 3.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.6 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.1 1.2 GO:0046548 retinal rod cell development(GO:0046548)
0.1 3.7 GO:0007568 aging(GO:0007568)
0.1 0.4 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 2.0 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 8.2 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.1 4.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 6.0 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 27.2 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1 3.8 GO:0046785 microtubule polymerization(GO:0046785)
0.1 4.0 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 1.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.9 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 1.8 GO:0046849 bone remodeling(GO:0046849)
0.1 1.2 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.1 25.3 GO:0006874 cellular calcium ion homeostasis(GO:0006874)
0.1 0.5 GO:0032218 riboflavin transport(GO:0032218)
0.1 9.9 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 0.7 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 3.3 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.1 0.7 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 1.1 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 0.7 GO:0042694 muscle cell fate specification(GO:0042694)
0.1 4.3 GO:0032835 glomerulus development(GO:0032835)
0.1 1.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 1.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.3 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.1 2.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 4.5 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 1.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 1.0 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.9 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 2.7 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 1.7 GO:0008033 tRNA processing(GO:0008033)
0.0 6.4 GO:0007601 visual perception(GO:0007601)
0.0 1.1 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 0.2 GO:0032941 body fluid secretion(GO:0007589) secretion by tissue(GO:0032941) mucus secretion(GO:0070254)
0.0 0.9 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 1.7 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.7 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.5 GO:0014020 neural tube closure(GO:0001843) primary neural tube formation(GO:0014020)
0.0 0.4 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 1.1 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 0.7 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 0.4 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 3.4 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 2.1 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 18.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
1.4 23.1 GO:0030315 T-tubule(GO:0030315)
1.3 17.1 GO:1990246 uniplex complex(GO:1990246)
1.3 31.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
1.3 8.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.3 26.7 GO:0031430 M band(GO:0031430)
1.2 7.1 GO:0031258 lamellipodium membrane(GO:0031258)
1.1 8.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.1 4.3 GO:0060171 stereocilium membrane(GO:0060171)
0.9 7.3 GO:0001772 immunological synapse(GO:0001772)
0.7 5.6 GO:0070552 BRISC complex(GO:0070552)
0.6 25.7 GO:0005861 troponin complex(GO:0005861)
0.6 2.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.5 16.9 GO:0031594 neuromuscular junction(GO:0031594)
0.5 28.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.5 3.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.5 2.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.4 4.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.4 3.5 GO:0030428 cell septum(GO:0030428)
0.4 17.3 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.4 4.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.4 17.2 GO:0031941 filamentous actin(GO:0031941)
0.3 2.4 GO:0032019 mitochondrial cloud(GO:0032019)
0.3 28.6 GO:0000786 nucleosome(GO:0000786)
0.3 26.1 GO:0005581 collagen trimer(GO:0005581)
0.2 2.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 5.2 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.2 3.1 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.2 5.6 GO:0043186 P granule(GO:0043186)
0.2 1.5 GO:0016011 dystroglycan complex(GO:0016011)
0.2 6.8 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 3.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 4.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.9 GO:0072487 MSL complex(GO:0072487)
0.1 35.0 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 6.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.7 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 0.2 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 2.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 5.3 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 34.1 GO:0031012 extracellular matrix(GO:0031012)
0.1 10.5 GO:0005882 intermediate filament(GO:0005882)
0.1 0.4 GO:0061702 inflammasome complex(GO:0061702)
0.1 7.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 2.0 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 2.0 GO:0030667 secretory granule membrane(GO:0030667)
0.1 4.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 1.3 GO:0016529 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.1 1.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 2.0 GO:0035861 site of double-strand break(GO:0035861)
0.1 1.5 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.1 1.0 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 3.8 GO:0030286 dynein complex(GO:0030286)
0.1 4.7 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.6 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.1 11.9 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 3.3 GO:0005814 centriole(GO:0005814)
0.0 1.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.1 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 2.2 GO:0030018 Z disc(GO:0030018)
0.0 3.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 4.5 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 25.5 GO:0005615 extracellular space(GO:0005615)
0.0 1.5 GO:0001726 ruffle(GO:0001726)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 23.5 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
3.9 11.7 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
3.0 11.9 GO:0101006 protein histidine phosphatase activity(GO:0101006)
2.9 11.6 GO:0033149 FFAT motif binding(GO:0033149)
2.9 31.9 GO:0035804 structural constituent of egg coat(GO:0035804)
2.5 7.4 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
2.3 18.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
2.2 8.9 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
1.9 31.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.9 5.6 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
1.5 7.3 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
1.4 13.7 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
1.3 3.9 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
1.3 19.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
1.2 7.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
1.2 12.8 GO:0032036 myosin heavy chain binding(GO:0032036)
1.1 25.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
1.1 10.0 GO:0048039 ubiquinone binding(GO:0048039)
1.1 3.3 GO:0030882 lipid antigen binding(GO:0030882)
1.0 3.1 GO:0046923 ER retention sequence binding(GO:0046923)
1.0 4.0 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.8 3.4 GO:0031005 filamin binding(GO:0031005)
0.8 18.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.8 2.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.7 10.5 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.7 2.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.7 2.0 GO:0071568 UFM1 transferase activity(GO:0071568)
0.7 13.4 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.7 11.1 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.6 7.1 GO:0004046 aminoacylase activity(GO:0004046)
0.6 3.8 GO:0004104 cholinesterase activity(GO:0004104)
0.6 10.2 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
0.6 1.8 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.6 1.7 GO:0008397 sterol 12-alpha-hydroxylase activity(GO:0008397)
0.5 28.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.5 3.2 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.5 3.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.5 6.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.4 3.5 GO:0004100 chitin synthase activity(GO:0004100)
0.4 5.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.4 1.7 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.4 1.7 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.4 27.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.4 7.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.4 11.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.4 6.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.4 1.5 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.3 2.4 GO:0004630 phospholipase D activity(GO:0004630)
0.3 9.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 10.2 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.3 2.9 GO:0004977 melanocortin receptor activity(GO:0004977)
0.3 1.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.3 2.7 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.3 6.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.3 4.0 GO:0003823 antigen binding(GO:0003823)
0.3 1.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.3 1.5 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.3 1.8 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.2 3.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 5.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 2.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.2 7.6 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.2 0.9 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.2 6.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 1.7 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2 1.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.2 1.8 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 8.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 2.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 1.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 5.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 7.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 5.8 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 3.6 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.2 3.9 GO:0070492 oligosaccharide binding(GO:0070492)
0.2 13.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.2 1.6 GO:0005522 profilin binding(GO:0005522)
0.2 2.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1 0.7 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 2.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 16.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 3.3 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 3.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 3.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 2.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 3.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 1.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.3 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 8.4 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.5 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.8 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.8 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 1.5 GO:0043236 laminin binding(GO:0043236)
0.1 1.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.6 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.5 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 6.4 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 1.9 GO:0008378 galactosyltransferase activity(GO:0008378)
0.1 4.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 2.1 GO:0017046 peptide hormone binding(GO:0017046)
0.1 2.4 GO:0005109 frizzled binding(GO:0005109)
0.1 1.0 GO:0002039 p53 binding(GO:0002039)
0.1 1.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 2.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 11.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 48.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 20.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 28.9 GO:0005525 GTP binding(GO:0005525)
0.0 5.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 2.5 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 1.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.5 GO:0045159 myosin II binding(GO:0045159)
0.0 2.4 GO:0008201 heparin binding(GO:0008201)
0.0 6.7 GO:0020037 heme binding(GO:0020037) tetrapyrrole binding(GO:0046906)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 6.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 2.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.7 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 8.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 2.1 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 3.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.5 GO:0019838 growth factor binding(GO:0019838)
0.0 6.6 GO:0003682 chromatin binding(GO:0003682)
0.0 14.7 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 1.0 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 3.3 GO:0051015 actin filament binding(GO:0051015)
0.0 6.0 GO:0008289 lipid binding(GO:0008289)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 12.5 PID ARF6 PATHWAY Arf6 signaling events
0.4 11.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.4 10.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.3 1.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.3 9.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 32.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 9.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 8.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 1.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 1.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 11.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 4.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 3.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 0.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.3 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 ST GA13 PATHWAY G alpha 13 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 9.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.8 16.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.8 21.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.5 3.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.5 3.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 7.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.4 4.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 4.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 4.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.3 11.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 1.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 2.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 2.2 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.2 3.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 4.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 6.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 5.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 2.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 1.8 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.1 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 3.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 5.0 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.1 1.0 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 3.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 3.5 REACTOME TRANSLATION Genes involved in Translation
0.0 4.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse