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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for tbr1b_tbx16+tbx16l+tbx2a+tbx2b

Z-value: 1.14

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Transcription factors associated with tbr1b_tbx16+tbx16l+tbx2a+tbx2b

Gene Symbol Gene ID Gene Info
tbr1b
ENSDARG00000004712 T-box brain transcription factor 1b
tbx2b
ENSDARG00000006120 T-box transcription factor 2b
tbx16l
ENSDARG00000006939 T-box transcription factor 16, like
tbx16
ENSDARG00000007329 T-box transcription factor 16
tbx2a
ENSDARG00000018025 T-box transcription factor 2a
tbx2a
ENSDARG00000109541 T-box transcription factor 2a
tbx2b
ENSDARG00000116135 T-box transcription factor 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tbx16dr11_v1_chr8_-_51753604_51753604-0.771.6e-19Click!
tbr1bdr11_v1_chr9_-_51436377_51436377-0.692.0e-14Click!
tbx6ldr11_v1_chr5_+_42280372_42280372-0.251.4e-02Click!
tbx2adr11_v1_chr5_-_56513825_565138250.151.5e-01Click!
tbx2bdr11_v1_chr15_+_27364394_273643940.084.2e-01Click!

Activity profile of tbr1b_tbx16+tbx16l+tbx2a+tbx2b motif

Sorted Z-values of tbr1b_tbx16+tbx16l+tbx2a+tbx2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_51846224 28.15 ENSDART00000184663
LT631684.2

chr7_+_7048245 15.40 ENSDART00000001649
actn3b
actinin alpha 3b
chr7_+_6969909 12.59 ENSDART00000189886
actn3b
actinin alpha 3b
chr17_+_26965351 11.42 ENSDART00000114215
ENSDART00000147192
grhl3
grainyhead-like transcription factor 3
chr7_+_69841017 11.22 ENSDART00000169107
FO818704.1

chr9_-_42873700 10.73 ENSDART00000125953
ttn.1
titin, tandem duplicate 1
chr3_+_32526263 10.62 ENSDART00000150897
si:ch73-367p23.2
si:ch73-367p23.2
chr19_+_791538 9.72 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr23_+_23232136 9.11 ENSDART00000126479
ENSDART00000187764
plekhn1
pleckstrin homology domain containing, family N member 1
chr13_-_15702672 8.63 ENSDART00000144445
ENSDART00000168950
ckba
creatine kinase, brain a
chr14_+_21106444 8.61 ENSDART00000075744
ENSDART00000132363
aldob
aldolase b, fructose-bisphosphate
chr11_-_25257045 8.58 ENSDART00000130477
snai1a
snail family zinc finger 1a
chr6_+_56141852 7.95 ENSDART00000149665
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr23_-_20100436 7.93 ENSDART00000143445
si:dkey-32e6.6
si:dkey-32e6.6
chr3_-_61181018 7.90 ENSDART00000187970
pvalb4
parvalbumin 4
chr21_-_22928214 7.83 ENSDART00000182760
dub
duboraya
chr3_-_32603191 7.79 ENSDART00000150997
si:ch73-248e21.7
si:ch73-248e21.7
chr7_+_39446247 7.73 ENSDART00000033610
ENSDART00000099015
tnnt3b
troponin T type 3b (skeletal, fast)
chr15_+_32711663 7.73 ENSDART00000157854
ENSDART00000167515
postnb
periostin, osteoblast specific factor b
chr18_-_7539166 7.62 ENSDART00000133541
si:dkey-30c15.2
si:dkey-30c15.2
chr2_+_36007449 7.51 ENSDART00000161837
lamc2
laminin, gamma 2
chr22_+_661711 7.36 ENSDART00000113795
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr11_-_25257595 7.35 ENSDART00000123567
snai1a
snail family zinc finger 1a
chr12_+_6002715 7.31 ENSDART00000114961
si:ch211-131k2.3
si:ch211-131k2.3
chr1_-_49521407 7.28 ENSDART00000189845
ENSDART00000143474
zp3c
zona pellucida glycoprotein 3c
chr18_+_29156827 7.23 ENSDART00000137587
ENSDART00000135633
ppfibp2a
PTPRF interacting protein, binding protein 2a (liprin beta 2)
chr22_+_26600834 7.10 ENSDART00000157411
adcy9
adenylate cyclase 9
chr5_+_43006422 7.03 ENSDART00000009182
aqp3a
aquaporin 3a
chr7_+_38750871 6.98 ENSDART00000114238
ENSDART00000052325
ENSDART00000137001
f2
coagulation factor II (thrombin)
chr7_-_52417777 6.93 ENSDART00000110265
myzap
myocardial zonula adherens protein
chr25_-_27819838 6.84 ENSDART00000067106
lmod2a
leiomodin 2 (cardiac) a
chr13_+_33606739 6.72 ENSDART00000026464
cfl1l
cofilin 1 (non-muscle), like
chr9_-_443451 6.70 ENSDART00000165642
si:dkey-11f4.14
si:dkey-11f4.14
chr19_+_30990815 6.66 ENSDART00000134645
sync
syncoilin, intermediate filament protein
chr19_-_7420867 6.58 ENSDART00000081741
rab25a
RAB25, member RAS oncogene family a
chr19_+_7735157 6.42 ENSDART00000186717
tuft1b
tuftelin 1b
chr21_-_11575626 6.15 ENSDART00000133171
cast
calpastatin
chr7_+_3357973 6.13 ENSDART00000172853
si:ch211-285c6.5
si:ch211-285c6.5
chr10_-_1961930 6.08 ENSDART00000122446
tdgf1
teratocarcinoma-derived growth factor 1
chr12_-_10567188 5.87 ENSDART00000144283
myof
myoferlin
chr24_+_35975398 5.72 ENSDART00000173058
obscnb
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr15_+_32711172 5.63 ENSDART00000163936
ENSDART00000168135
postnb
periostin, osteoblast specific factor b
chr7_+_65240227 5.61 ENSDART00000168287
bco1l
beta-carotene oxygenase 1, like
chr14_+_17376940 5.53 ENSDART00000054590
ENSDART00000010148
spon2b
spondin 2b, extracellular matrix protein
chr14_+_48862987 5.51 ENSDART00000167810
zgc:154054
zgc:154054
chr20_-_26846028 5.48 ENSDART00000136687
mylk4b
myosin light chain kinase family, member 4b
chr10_+_43994471 5.42 ENSDART00000138242
ENSDART00000186359
cldn5b
claudin 5b
chr18_+_7591381 5.42 ENSDART00000136313
si:dkeyp-1h4.6
si:dkeyp-1h4.6
chr22_+_25693295 5.39 ENSDART00000123888
ENSDART00000150783
si:dkeyp-98a7.4
si:dkeyp-98a7.3
si:dkeyp-98a7.4
si:dkeyp-98a7.3
chr5_-_25037454 5.38 ENSDART00000027237
abo
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr23_+_9867483 5.33 ENSDART00000023099
slc16a7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr22_+_25704430 5.32 ENSDART00000143776
si:dkeyp-98a7.3
si:dkeyp-98a7.3
chr22_-_24757785 5.30 ENSDART00000078225
vtg5
vitellogenin 5
chr8_+_39663612 5.29 ENSDART00000188074
BX005328.1

chr2_-_30182353 5.25 ENSDART00000019149
rpl7
ribosomal protein L7
chr22_+_25681911 5.23 ENSDART00000113381
si:dkeyp-98a7.3
si:dkeyp-98a7.3
chr19_+_2590182 5.22 ENSDART00000162293
si:ch73-345f18.3
si:ch73-345f18.3
chr7_-_19614916 5.15 ENSDART00000169029
zgc:194655
zgc:194655
chr22_+_25715925 5.13 ENSDART00000150650
si:dkeyp-98a7.7
si:dkeyp-98a7.7
chr17_-_8907668 4.97 ENSDART00000155996
ENSDART00000155624
nkl.1
NK-lysin tandem duplicate 1
chr8_-_24252933 4.97 ENSDART00000057624
zgc:110353
zgc:110353
chr22_+_25687525 4.95 ENSDART00000135717
si:dkeyp-98a7.3
si:dkeyp-98a7.3
chr13_+_31757331 4.94 ENSDART00000044282
hif1aa
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) a
chr7_-_53117131 4.94 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cdh1
cadherin 1, type 1, E-cadherin (epithelial)
chr25_+_4960509 4.93 ENSDART00000155984
si:ch73-265h17.4
si:ch73-265h17.4
chr11_+_6650966 4.92 ENSDART00000131236
si:dkey-246j7.1
si:dkey-246j7.1
chr10_+_3127809 4.92 ENSDART00000185500
ckmt2a
creatine kinase, mitochondrial 2a (sarcomeric)
chr13_+_18533005 4.85 ENSDART00000136024
ftr14l
finTRIM family, member 14-like
chr19_+_9305964 4.83 ENSDART00000136241
si:ch73-15n24.1
si:ch73-15n24.1
chr21_+_10866421 4.81 ENSDART00000137858
alpk2
alpha-kinase 2
chr13_-_9442942 4.78 ENSDART00000138833
grxcr1
glutaredoxin, cysteine rich 1
chr8_-_11229523 4.76 ENSDART00000002164
unc45b
unc-45 myosin chaperone B
chr3_+_43086548 4.72 ENSDART00000163579
si:dkey-43p13.5
si:dkey-43p13.5
chr5_+_27525477 4.70 ENSDART00000051491
sfrp1a
secreted frizzled-related protein 1a
chr24_-_27419198 4.63 ENSDART00000141124
ccl34b.4
chemokine (C-C motif) ligand 34b, duplicate 4
chr6_-_46941245 4.60 ENSDART00000037875
igfn1.1
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 1
chr24_-_34680956 4.58 ENSDART00000171009
ctnna1
catenin (cadherin-associated protein), alpha 1
chr11_+_37178271 4.56 ENSDART00000161771
itih3b
inter-alpha-trypsin inhibitor heavy chain 3b
chr12_+_10062953 4.47 ENSDART00000148689
slc4a1b
solute carrier family 4 (anion exchanger), member 1b (Diego blood group)
chr22_+_25710148 4.42 ENSDART00000150446
si:dkeyp-98a7.4
si:dkeyp-98a7.4
chr10_-_32524035 4.40 ENSDART00000137608
dgat2
diacylglycerol O-acyltransferase 2
chr2_-_42234484 4.40 ENSDART00000132617
ENSDART00000136690
ENSDART00000141358
apom
apolipoprotein M
chr23_-_29003864 4.38 ENSDART00000148257
casz1
castor zinc finger 1
chr9_-_40011673 4.37 ENSDART00000184726
IKZF2
si:zfos-1425h8.1
chr17_+_51517750 4.37 ENSDART00000180896
ENSDART00000193528
pxdn
peroxidasin
chr4_-_11580948 4.35 ENSDART00000049066
net1
neuroepithelial cell transforming 1
chr16_-_32233463 4.35 ENSDART00000102016
calhm6
calcium homeostasis modulator family member 6
chr7_-_58776400 4.33 ENSDART00000167433
sox17
SRY (sex determining region Y)-box 17
chr5_-_4204580 4.32 ENSDART00000049197
ENSDART00000132130
si:ch211-283g2.1
si:ch211-283g2.1
chr5_-_44843738 4.31 ENSDART00000003926
fbp1a
fructose-1,6-bisphosphatase 1a
chr25_+_36292057 4.30 ENSDART00000152329
bmb
brambleberry
chr19_+_917852 4.27 ENSDART00000082466
tgfbr2a
transforming growth factor beta receptor 2a
chr22_+_25720725 4.24 ENSDART00000150778
si:dkeyp-98a7.8
si:dkeyp-98a7.8
chr21_-_34951265 4.24 ENSDART00000135222
lipia
lipase, member Ia
chr15_-_5580093 4.24 ENSDART00000143726
wdr62
WD repeat domain 62
chr22_+_1123110 4.22 ENSDART00000171017
si:ch1073-181h11.2
si:ch1073-181h11.2
chr1_-_6028876 4.22 ENSDART00000168117
si:ch1073-345a8.1
si:ch1073-345a8.1
chr24_-_36593876 4.18 ENSDART00000160901
CABZ01055365.1

chr18_-_48550426 4.17 ENSDART00000145189
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr9_-_21970067 4.16 ENSDART00000009920
lmo7a
LIM domain 7a
chr5_-_38170996 4.10 ENSDART00000145805
si:ch211-284e13.12
si:ch211-284e13.12
chr13_-_51922290 4.04 ENSDART00000168648
srfb
serum response factor b
chr13_-_41908583 4.03 ENSDART00000136515
ipmka
inositol polyphosphate multikinase a
chr7_+_65673885 3.99 ENSDART00000169182
parvab
parvin, alpha b
chr1_+_8521323 3.98 ENSDART00000121439
ENSDART00000103626
ENSDART00000141283
mief2
mitochondrial elongation factor 2
chr16_+_13993285 3.98 ENSDART00000139130
ENSDART00000130353
si:dkey-85k15.7
fdps
si:dkey-85k15.7
farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
chr21_+_5531138 3.97 ENSDART00000163825
ly6m6
lymphocyte antigen 6 family member M6
chr2_+_45081489 3.96 ENSDART00000123966
chrng
cholinergic receptor, nicotinic, gamma
chr21_+_28445052 3.95 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr12_-_14143344 3.94 ENSDART00000152742
buc2l
bucky ball 2-like
chr13_+_1799003 3.93 ENSDART00000029343
col21a1
collagen, type XXI, alpha 1
chr5_-_32505109 3.91 ENSDART00000188219
ntmt1
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr10_+_33171501 3.90 ENSDART00000159666
myl10
myosin, light chain 10, regulatory
chr16_+_29492937 3.90 ENSDART00000011497
ctsk
cathepsin K
chr16_-_12723738 3.89 ENSDART00000080414
sbk3
SH3 domain binding kinase family, member 3
chr7_+_2797795 3.86 ENSDART00000161208
si:ch211-217i17.1
si:ch211-217i17.1
chr1_+_51615672 3.85 ENSDART00000165117
zgc:165656
zgc:165656
chr5_-_42878178 3.85 ENSDART00000162981
CXCL11 (1 of many)
C-X-C motif chemokine ligand 11
chr18_+_8340886 3.85 ENSDART00000081132
cpt1b
carnitine palmitoyltransferase 1B (muscle)
chr8_+_36142734 3.84 ENSDART00000159361
ENSDART00000161194
mhc2b
major histocompatibility complex class II integral membrane beta chain gene
chr24_-_18919562 3.83 ENSDART00000144244
ENSDART00000106188
ENSDART00000182518
cpa6
carboxypeptidase A6
chr14_+_97017 3.83 ENSDART00000159300
ENSDART00000169523
mcm7
minichromosome maintenance complex component 7
chr6_+_36877968 3.81 ENSDART00000155187
traf3ip2l
TRAF3 interacting protein 2-like
chr22_-_35330532 3.78 ENSDART00000172654
FO818743.1

chr10_-_25816558 3.77 ENSDART00000017240
postna
periostin, osteoblast specific factor a
chr9_+_8851819 3.69 ENSDART00000160004
col4a2
collagen, type IV, alpha 2
chr17_+_34186632 3.68 ENSDART00000014306
mpp5a
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr24_-_26369185 3.65 ENSDART00000080039
lrrc31
leucine rich repeat containing 31
chr7_+_13988075 3.65 ENSDART00000186812
furina
furin (paired basic amino acid cleaving enzyme) a
chr15_-_43164591 3.64 ENSDART00000171305
ap1s3a
adaptor-related protein complex 1, sigma 3 subunit, a
chr12_+_13244149 3.62 ENSDART00000186984
ENSDART00000105896
atp2a1l
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr19_-_34999379 3.60 ENSDART00000051751
zgc:113424
zgc:113424
chr6_+_36839509 3.60 ENSDART00000190605
ENSDART00000104160
zgc:110788
zgc:110788
chr22_+_25734180 3.59 ENSDART00000143367
si:dkeyp-98a7.9
si:dkeyp-98a7.9
chr13_-_25767210 3.58 ENSDART00000131792
pdlim1
PDZ and LIM domain 1 (elfin)
chr17_-_5583345 3.57 ENSDART00000035944
clic5a
chloride intracellular channel 5a
chr15_-_47848544 3.57 ENSDART00000098711
eif3k
eukaryotic translation initiation factor 3, subunit K
chr18_+_54354 3.50 ENSDART00000097163
zgc:158482
zgc:158482
chr7_-_5070794 3.48 ENSDART00000097877
ltb4r2a
leukotriene B4 receptor 2a
chr19_-_5332784 3.48 ENSDART00000010373
krt1-19d
keratin, type 1, gene 19d
chr22_-_9649627 3.46 ENSDART00000164721
si:dkey-286j17.4
si:dkey-286j17.4
chr3_-_23643751 3.46 ENSDART00000078425
ENSDART00000140264
eve1
even-skipped-like1
chr5_-_68022631 3.44 ENSDART00000143199
wasf3a
WAS protein family, member 3a
chr22_-_17652112 3.42 ENSDART00000189205
hmha1b
histocompatibility (minor) HA-1 b
chr16_-_20312146 3.41 ENSDART00000134980
si:dkeyp-86h10.3
si:dkeyp-86h10.3
chr16_-_54455573 3.41 ENSDART00000075275
pklr
pyruvate kinase L/R
chr21_-_3700334 3.41 ENSDART00000137844
atp8b1
ATPase phospholipid transporting 8B1
chr3_-_39171968 3.39 ENSDART00000154494
si:dkeyp-57f11.2
si:dkeyp-57f11.2
chr8_-_25327809 3.39 ENSDART00000137242
eps8l3b
EPS8-like 3b
chr10_+_38610741 3.38 ENSDART00000126444
mmp13a
matrix metallopeptidase 13a
chr17_+_38255105 3.38 ENSDART00000005296
nkx2.9
NK2 transcription factor related, locus 9 (Drosophila)
chr10_-_13116337 3.37 ENSDART00000164568
musk
muscle, skeletal, receptor tyrosine kinase
chr15_-_1590858 3.37 ENSDART00000081875
nnr
nanor
chr11_+_27274355 3.36 ENSDART00000113707
fbln2
fibulin 2
chr3_+_32526799 3.36 ENSDART00000185755
si:ch73-367p23.2
si:ch73-367p23.2
chr16_+_38201840 3.35 ENSDART00000044971
myo1eb
myosin IE, b
chr13_-_27354003 3.33 ENSDART00000101479
ENSDART00000044652
ddx43
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr19_-_20270178 3.32 ENSDART00000144891
ENSDART00000090883
gpnmb
glycoprotein (transmembrane) nmb
chr2_+_38161318 3.31 ENSDART00000044264
mmp14b
matrix metallopeptidase 14b (membrane-inserted)
chr7_-_38638809 3.31 ENSDART00000144341
c6ast4
six-cysteine containing astacin protease 4
chr10_+_38417512 3.31 ENSDART00000112457
samsn1b
SAM domain, SH3 domain and nuclear localisation signals 1b
chr4_+_14981854 3.30 ENSDART00000067046
cax1
cation/H+ exchanger protein 1
chr20_+_15600167 3.25 ENSDART00000171991
faslg
Fas ligand (TNF superfamily, member 6)
chr2_-_58257624 3.25 ENSDART00000098940
foxl2b
forkhead box L2b
chr6_+_41039166 3.23 ENSDART00000125659
entpd8
ectonucleoside triphosphate diphosphohydrolase 8
chr10_-_11376491 3.22 ENSDART00000145346
plac8.2
placenta-specific 8, tandem duplicate 2
chr16_+_21790870 3.21 ENSDART00000155039
trim108
tripartite motif containing 108
chr6_-_46861676 3.21 ENSDART00000188712
ENSDART00000190148
igfn1.3
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr20_-_33961697 3.19 ENSDART00000061765
selp
selectin P
chr15_+_7054754 3.16 ENSDART00000149800
foxl2a
forkhead box L2a
chr11_-_7380674 3.16 ENSDART00000014979
ENSDART00000103418
vtg3
vitellogenin 3, phosvitinless
chr5_+_33498253 3.16 ENSDART00000140993
ms4a17c.2
membrane-spanning 4-domains, subfamily A, member 17c.2
chr2_+_2470687 3.15 ENSDART00000184024
ENSDART00000061955
myl13
myosin, light chain 13
chr10_+_252425 3.14 ENSDART00000059478
lrrc32
leucine rich repeat containing 32
chr21_+_21374277 3.14 ENSDART00000079431
rtn2b
reticulon 2b
chr10_-_1961576 3.13 ENSDART00000042441
tdgf1
teratocarcinoma-derived growth factor 1
chr16_+_29516098 3.12 ENSDART00000174895
ctss2.2
cathepsin S, ortholog 2, tandem duplicate 2
chr5_-_69180587 3.09 ENSDART00000156681
ENSDART00000160753
zgc:171967
zgc:171967
chr20_-_51946052 3.09 ENSDART00000074325
dusp10
dual specificity phosphatase 10
chr17_-_8312923 3.09 ENSDART00000064678
lft2
lefty2
chr16_+_23978978 3.08 ENSDART00000058964
ENSDART00000135084
apoa2
apolipoprotein A-II
chr8_+_50531709 3.07 ENSDART00000193352
PEBP4
phosphatidylethanolamine binding protein 4
chr18_+_27300700 3.07 ENSDART00000140444
plekha7a
pleckstrin homology domain containing, family A member 7a
chr7_+_15329819 3.07 ENSDART00000006018
mespaa
mesoderm posterior aa
chr22_+_15315655 3.06 ENSDART00000141249
sult3st3
sulfotransferase family 3, cytosolic sulfotransferase 3
chr5_-_28016805 3.05 ENSDART00000078642
vps37b
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr24_+_35564668 3.04 ENSDART00000122734
cebpd
CCAAT/enhancer binding protein (C/EBP), delta
chr7_+_15313443 3.04 ENSDART00000045385
mespba
mesoderm posterior ba
chr23_-_16734009 3.03 ENSDART00000125449
si:ch211-224l10.4
si:ch211-224l10.4
chr11_+_21050326 3.02 ENSDART00000065984
zgc:113307
zgc:113307
chr25_+_3507368 3.01 ENSDART00000157777
zgc:153293
zgc:153293
chr24_-_40700596 3.01 ENSDART00000162635
smyhc2
slow myosin heavy chain 2
chr6_-_26895314 2.98 ENSDART00000134259
hdlbpa
high density lipoprotein binding protein a
chr3_+_47245764 2.97 ENSDART00000193581
tnfsf14
TNF superfamily member 14
chr9_+_8380728 2.97 ENSDART00000133501
si:ch1073-75o15.4
si:ch1073-75o15.4
chr11_+_37251825 2.96 ENSDART00000169804
il17rc
interleukin 17 receptor C
chr5_-_16475682 2.96 ENSDART00000090695
piwil2
piwi-like RNA-mediated gene silencing 2
chr9_-_7390388 2.94 ENSDART00000132392
slc23a3
solute carrier family 23, member 3
chr5_+_61843752 2.94 ENSDART00000130940
CR759879.1
Danio rerio interferon-induced protein with tetratricopeptide repeats 5 (LOC572297), mRNA.
chr7_+_25221757 2.93 ENSDART00000173551
exoc6b
exocyst complex component 6B

Network of associatons between targets according to the STRING database.

First level regulatory network of tbr1b_tbx16+tbx16l+tbx2a+tbx2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.2 GO:0090008 hypoblast development(GO:0090008)
2.6 7.8 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
2.4 7.2 GO:0005986 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
2.3 9.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
2.2 6.7 GO:0030043 actin filament fragmentation(GO:0030043)
2.1 6.4 GO:0048496 maintenance of organ identity(GO:0048496)
1.6 4.9 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
1.5 1.5 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
1.4 8.5 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
1.3 4.0 GO:0052576 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
1.3 5.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
1.3 3.9 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
1.3 8.8 GO:0006953 acute-phase response(GO:0006953)
1.3 3.8 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
1.1 4.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
1.0 13.5 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
1.0 3.1 GO:0045218 zonula adherens maintenance(GO:0045218)
1.0 4.9 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.9 2.8 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.9 2.8 GO:1902103 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.9 19.6 GO:0008078 mesodermal cell migration(GO:0008078)
0.9 6.1 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.8 15.1 GO:0016203 muscle attachment(GO:0016203)
0.8 6.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.7 11.1 GO:0060325 face morphogenesis(GO:0060325)
0.7 2.2 GO:0032640 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.7 2.8 GO:0055021 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.7 2.8 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.7 2.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.7 2.7 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.7 10.7 GO:0048769 sarcomerogenesis(GO:0048769)
0.7 4.0 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.7 2.0 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.6 2.6 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.6 1.9 GO:0005997 xylulose metabolic process(GO:0005997)
0.6 3.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.6 1.2 GO:0070199 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.6 8.0 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.6 1.2 GO:0048322 axial mesoderm formation(GO:0048320) axial mesodermal cell differentiation(GO:0048321) axial mesodermal cell fate commitment(GO:0048322) axial mesodermal cell fate specification(GO:0048327)
0.6 9.0 GO:0048382 mesendoderm development(GO:0048382)
0.6 5.4 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.6 2.4 GO:0061033 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.6 3.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.6 2.8 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.5 2.2 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.5 8.0 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.5 9.0 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.5 3.2 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.5 1.6 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.5 3.7 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.5 2.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.5 5.5 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.5 2.0 GO:0034087 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.5 1.5 GO:0060584 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.5 1.9 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.5 1.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.5 1.4 GO:1901004 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.5 3.6 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.5 4.1 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.4 1.3 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.4 2.7 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.4 2.1 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.4 1.3 GO:0001783 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.4 3.4 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.4 1.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.4 1.6 GO:0003413 plasma membrane repair(GO:0001778) chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.4 2.0 GO:0048730 epidermis morphogenesis(GO:0048730)
0.4 3.2 GO:0031179 peptide modification(GO:0031179)
0.4 2.4 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.4 8.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.4 6.9 GO:0009437 carnitine metabolic process(GO:0009437)
0.4 1.5 GO:0051876 pigment granule dispersal(GO:0051876)
0.4 1.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.4 1.1 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.4 1.1 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.4 1.1 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.4 2.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.4 2.5 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.4 4.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.3 3.8 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.3 0.7 GO:0002676 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.3 6.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.3 2.4 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.3 2.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.3 1.3 GO:0070317 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.3 1.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.3 2.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.3 1.0 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.3 5.4 GO:0030259 lipid glycosylation(GO:0030259)
0.3 0.9 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.3 1.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.3 9.4 GO:0032355 response to estradiol(GO:0032355)
0.3 0.9 GO:1903961 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.3 5.1 GO:0019433 triglyceride catabolic process(GO:0019433)
0.3 2.0 GO:0006741 NADP biosynthetic process(GO:0006741)
0.3 1.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.3 2.9 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.3 1.1 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.3 1.4 GO:0071305 cellular response to vitamin D(GO:0071305)
0.3 3.1 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.3 2.4 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3 1.9 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.3 1.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.3 2.6 GO:0086003 cardiac muscle cell contraction(GO:0086003)
0.3 1.8 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.3 1.3 GO:0007584 response to nutrient(GO:0007584)
0.3 6.3 GO:0071456 cellular response to hypoxia(GO:0071456)
0.3 1.8 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.3 1.0 GO:0016038 absorption of visible light(GO:0016038)
0.2 10.2 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.2 3.4 GO:0032264 IMP salvage(GO:0032264)
0.2 2.2 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.2 2.7 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 1.2 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.2 3.1 GO:0003128 heart field specification(GO:0003128)
0.2 5.9 GO:0007520 myoblast fusion(GO:0007520)
0.2 0.9 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.2 2.5 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.2 3.4 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 0.7 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.2 2.1 GO:0021794 thalamus development(GO:0021794)
0.2 3.2 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.2 2.3 GO:0044030 regulation of DNA methylation(GO:0044030)
0.2 0.9 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.2 1.1 GO:0007525 somatic muscle development(GO:0007525)
0.2 7.9 GO:0043113 receptor clustering(GO:0043113)
0.2 11.5 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.2 1.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.2 1.5 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.2 1.5 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.2 0.6 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.2 1.5 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.2 2.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 0.8 GO:0051645 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.2 0.6 GO:0098725 somatic stem cell population maintenance(GO:0035019) symmetric cell division(GO:0098725)
0.2 1.0 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.2 1.0 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.2 0.6 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.2 1.2 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.2 1.2 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.2 4.5 GO:0048246 macrophage chemotaxis(GO:0048246)
0.2 1.2 GO:0071800 podosome assembly(GO:0071800)
0.2 3.1 GO:0055013 cardiac muscle cell development(GO:0055013)
0.2 21.4 GO:0030239 myofibril assembly(GO:0030239)
0.2 1.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.2 3.2 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.2 1.8 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.2 1.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2 0.5 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.2 0.5 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.2 0.7 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 3.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.2 4.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.2 3.1 GO:0030168 platelet activation(GO:0030168)
0.2 0.7 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.2 1.0 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.2 4.6 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.2 0.3 GO:0030238 female sex determination(GO:0030237) male sex determination(GO:0030238)
0.2 1.3 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.2 2.0 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.2 2.0 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.2 0.3 GO:0072679 thymocyte migration(GO:0072679)
0.2 7.1 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.2 1.0 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 3.5 GO:0048570 notochord morphogenesis(GO:0048570)
0.2 1.3 GO:0051673 membrane disruption in other organism(GO:0051673)
0.2 0.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 0.8 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.2 1.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 0.6 GO:0051012 microtubule sliding(GO:0051012)
0.2 2.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 3.0 GO:0043171 peptide catabolic process(GO:0043171)
0.1 5.2 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.7 GO:0071265 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.1 0.6 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.1 4.1 GO:0051923 sulfation(GO:0051923)
0.1 1.6 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 1.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 1.7 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 1.6 GO:0035587 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 2.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 7.3 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.1 2.1 GO:0042407 cristae formation(GO:0042407)
0.1 1.9 GO:0032098 regulation of appetite(GO:0032098)
0.1 2.9 GO:0032438 melanosome organization(GO:0032438)
0.1 1.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.8 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 0.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.9 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 2.3 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.9 GO:0033628 regulation of cell adhesion mediated by integrin(GO:0033628)
0.1 0.5 GO:0007220 Notch receptor processing(GO:0007220) beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.1 0.1 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.1 3.7 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 0.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 1.6 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.7 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.1 1.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.6 GO:0045581 CD4-positive, alpha-beta T cell differentiation involved in immune response(GO:0002294) T-helper cell lineage commitment(GO:0002295) T cell lineage commitment(GO:0002360) alpha-beta T cell lineage commitment(GO:0002363) T-helper cell differentiation(GO:0042093) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) negative regulation of T cell differentiation(GO:0045581) negative regulation of lymphocyte differentiation(GO:0045620) regulation of T-helper cell differentiation(GO:0045622) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of alpha-beta T cell differentiation(GO:0046639) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320) regulation of T-helper 17 cell lineage commitment(GO:2000328) negative regulation of T-helper 17 cell lineage commitment(GO:2000329) positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.1 1.3 GO:0003207 cardiac chamber formation(GO:0003207)
0.1 1.0 GO:0050909 sensory perception of taste(GO:0050909)
0.1 1.2 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 3.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.3 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222)
0.1 1.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.5 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.9 GO:0002761 regulation of myeloid leukocyte differentiation(GO:0002761)
0.1 1.3 GO:0030048 actin filament-based movement(GO:0030048)
0.1 1.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 5.7 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 2.1 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 2.7 GO:0051014 actin filament severing(GO:0051014)
0.1 3.1 GO:0003094 glomerular filtration(GO:0003094)
0.1 1.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 2.8 GO:0016925 protein sumoylation(GO:0016925)
0.1 2.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.1 2.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.4 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.1 0.4 GO:0048901 anterior lateral line neuromast development(GO:0048901) anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.1 0.6 GO:0021535 cell migration in hindbrain(GO:0021535)
0.1 3.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 1.3 GO:0006570 tyrosine metabolic process(GO:0006570)
0.1 0.5 GO:0001955 blood vessel maturation(GO:0001955)
0.1 3.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.6 GO:0035627 ceramide transport(GO:0035627)
0.1 2.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 1.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 1.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 2.1 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.1 3.6 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 4.1 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.1 4.5 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 0.9 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 1.7 GO:0015914 phospholipid transport(GO:0015914)
0.1 4.0 GO:0048821 erythrocyte development(GO:0048821)
0.1 1.9 GO:0090148 membrane fission(GO:0090148)
0.1 2.9 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.9 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.1 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 2.9 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.1 1.2 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 1.4 GO:0006939 smooth muscle contraction(GO:0006939)
0.1 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.7 GO:0038203 TORC2 signaling(GO:0038203)
0.1 6.5 GO:0031101 fin regeneration(GO:0031101)
0.1 5.6 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 3.6 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 3.6 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 1.0 GO:0006119 oxidative phosphorylation(GO:0006119)
0.1 11.0 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.1 3.4 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.1 1.2 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.9 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.9 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.9 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 0.6 GO:0009303 rRNA transcription(GO:0009303)
0.1 3.6 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.1 1.5 GO:0042113 B cell activation(GO:0042113)
0.1 4.6 GO:0060215 primitive hemopoiesis(GO:0060215)
0.1 4.6 GO:0001894 tissue homeostasis(GO:0001894)
0.1 13.6 GO:0009617 response to bacterium(GO:0009617)
0.1 2.3 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.1 0.9 GO:0071545 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.1 2.5 GO:0051262 protein tetramerization(GO:0051262)
0.1 1.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.7 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 2.3 GO:0002062 chondrocyte differentiation(GO:0002062)
0.1 1.3 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.1 0.4 GO:0000272 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.6 GO:0002695 negative regulation of leukocyte activation(GO:0002695) negative regulation of cell activation(GO:0050866) negative regulation of lymphocyte activation(GO:0051250)
0.1 0.9 GO:0019835 cytolysis(GO:0019835)
0.1 1.4 GO:0006826 iron ion transport(GO:0006826)
0.1 0.6 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.1 3.6 GO:0006006 glucose metabolic process(GO:0006006)
0.1 2.9 GO:0022904 respiratory electron transport chain(GO:0022904)
0.1 1.5 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 0.8 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 2.8 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.6 GO:0043651 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.4 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 1.6 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.1 0.3 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1 2.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.6 GO:1901317 regulation of sperm motility(GO:1901317)
0.0 3.4 GO:0009612 response to mechanical stimulus(GO:0009612)
0.0 0.7 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.4 GO:0001707 mesoderm formation(GO:0001707)
0.0 3.3 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 5.2 GO:0006954 inflammatory response(GO:0006954)
0.0 1.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 1.3 GO:0006956 complement activation(GO:0006956)
0.0 1.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.7 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 1.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.2 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 2.6 GO:0033334 fin morphogenesis(GO:0033334)
0.0 0.6 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 1.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 2.7 GO:0009308 amine metabolic process(GO:0009308)
0.0 2.8 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 0.5 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.6 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.7 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 1.6 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.0 3.8 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 3.2 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.8 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 2.0 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.6 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 1.9 GO:0006414 translational elongation(GO:0006414)
0.0 1.2 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 0.7 GO:0051283 sequestering of calcium ion(GO:0051208) release of sequestered calcium ion into cytosol(GO:0051209) sequestering of metal ion(GO:0051238) regulation of sequestering of calcium ion(GO:0051282) negative regulation of sequestering of calcium ion(GO:0051283)
0.0 1.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 1.1 GO:0001946 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0 1.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.6 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0090151 protein import into mitochondrial inner membrane(GO:0045039) establishment of protein localization to mitochondrial membrane(GO:0090151)
0.0 0.5 GO:1901661 quinone metabolic process(GO:1901661)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.7 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.5 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.3 GO:0043270 positive regulation of ion transmembrane transporter activity(GO:0032414) positive regulation of transmembrane transport(GO:0034764) positive regulation of ion transmembrane transport(GO:0034767) positive regulation of ion transport(GO:0043270) positive regulation of cation transmembrane transport(GO:1904064)
0.0 0.1 GO:0003315 heart rudiment formation(GO:0003315)
0.0 0.6 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.2 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.7 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.1 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.7 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.2 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 1.5 GO:0030155 regulation of cell adhesion(GO:0030155)
0.0 0.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.6 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 1.1 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.9 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.1 GO:0036372 opsin transport(GO:0036372)
0.0 2.6 GO:0006955 immune response(GO:0006955)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.3 GO:1990923 PET complex(GO:1990923)
0.8 3.1 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.7 2.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.7 3.4 GO:0097433 dense body(GO:0097433)
0.6 3.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.6 1.8 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.6 10.6 GO:0030057 desmosome(GO:0030057)
0.5 9.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.5 3.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.4 1.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.4 2.0 GO:0031415 NatA complex(GO:0031415)
0.4 4.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.4 2.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 1.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.3 10.5 GO:0031672 A band(GO:0031672)
0.3 18.3 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.3 1.1 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.3 2.2 GO:0005614 interstitial matrix(GO:0005614)
0.3 4.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.3 1.3 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.2 11.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 1.0 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.2 0.9 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 3.8 GO:0042555 MCM complex(GO:0042555)
0.2 6.2 GO:0035861 site of double-strand break(GO:0035861)
0.2 9.7 GO:0031941 filamentous actin(GO:0031941)
0.2 0.8 GO:0030870 Mre11 complex(GO:0030870)
0.2 1.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 1.3 GO:0070847 core mediator complex(GO:0070847)
0.2 2.1 GO:0061617 MICOS complex(GO:0061617)
0.2 0.9 GO:1990071 TRAPPII protein complex(GO:1990071)
0.2 1.8 GO:0032420 stereocilium(GO:0032420)
0.2 1.1 GO:1902636 kinociliary basal body(GO:1902636)
0.2 3.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 10.5 GO:0022626 cytosolic ribosome(GO:0022626)
0.2 8.5 GO:0005902 microvillus(GO:0005902)
0.2 3.2 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.2 3.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.2 2.7 GO:0031209 SCAR complex(GO:0031209)
0.2 2.6 GO:0000792 heterochromatin(GO:0000792)
0.2 1.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 0.6 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 0.4 GO:0000939 condensed chromosome inner kinetochore(GO:0000939) condensed nuclear chromosome inner kinetochore(GO:0000941)
0.1 0.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.9 GO:0005922 connexon complex(GO:0005922)
0.1 15.1 GO:0005882 intermediate filament(GO:0005882)
0.1 2.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 3.1 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.8 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 0.6 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.5 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 6.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 42.8 GO:0031012 extracellular matrix(GO:0031012)
0.1 0.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 4.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304)
0.1 4.2 GO:0032587 ruffle membrane(GO:0032587)
0.1 2.8 GO:0005839 proteasome core complex(GO:0005839)
0.1 3.9 GO:0005581 collagen trimer(GO:0005581)
0.1 1.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.0 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.1 2.1 GO:0001726 ruffle(GO:0001726)
0.1 3.2 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 2.4 GO:0008305 integrin complex(GO:0008305)
0.1 1.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 9.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 0.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 91.3 GO:0005615 extracellular space(GO:0005615)
0.1 4.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.2 GO:0070187 telosome(GO:0070187)
0.1 1.1 GO:0098798 mitochondrial protein complex(GO:0098798)
0.1 7.7 GO:0030055 cell-substrate junction(GO:0030055)
0.1 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 7.5 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 4.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.2 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 12.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.9 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 4.1 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 2.2 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 6.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 0.5 GO:0035060 brahma complex(GO:0035060)
0.1 1.1 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 3.9 GO:0016324 apical plasma membrane(GO:0016324)
0.1 0.9 GO:0044545 NSL complex(GO:0044545)
0.1 0.3 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.9 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 4.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.5 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 2.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.9 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 2.9 GO:0005884 actin filament(GO:0005884)
0.0 2.9 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.7 GO:0071565 nBAF complex(GO:0071565)
0.0 1.0 GO:0005844 polysome(GO:0005844)
0.0 2.5 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.6 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.3 GO:0000776 kinetochore(GO:0000776)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 7.4 GO:0005740 mitochondrial envelope(GO:0005740)
0.0 4.3 GO:0005730 nucleolus(GO:0005730)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 9.3 GO:0005739 mitochondrion(GO:0005739)
0.0 0.1 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 2.1 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.8 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 15.9 GO:0051059 NF-kappaB binding(GO:0051059)
3.0 9.1 GO:1901612 cardiolipin binding(GO:1901612)
2.4 7.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
2.0 7.9 GO:0070052 collagen V binding(GO:0070052)
1.8 7.0 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
1.3 4.0 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
1.3 4.0 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
1.3 3.9 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
1.2 8.5 GO:0045735 nutrient reservoir activity(GO:0045735)
1.2 3.5 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
1.0 13.5 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
1.0 13.4 GO:0070697 activin receptor binding(GO:0070697)
1.0 3.1 GO:0070097 delta-catenin binding(GO:0070097)
0.9 2.8 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.9 6.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.8 5.8 GO:0004974 leukotriene receptor activity(GO:0004974)
0.8 3.3 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.8 12.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.8 4.0 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.8 3.8 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.8 8.3 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.7 4.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.7 3.4 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.7 5.3 GO:0034584 piRNA binding(GO:0034584)
0.6 6.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.6 5.4 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.6 2.3 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.6 1.7 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6 6.3 GO:0005523 tropomyosin binding(GO:0005523)
0.6 3.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.5 3.8 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.5 2.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.5 2.1 GO:0051916 C-X-C chemokine receptor activity(GO:0016494) granulocyte colony-stimulating factor binding(GO:0051916)
0.5 9.0 GO:0032190 acrosin binding(GO:0032190)
0.5 7.9 GO:0031386 protein tag(GO:0031386)
0.5 2.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.5 2.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.5 2.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.5 3.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.4 2.7 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.4 1.7 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.4 5.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 13.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.4 6.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.4 2.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.4 4.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.4 3.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.4 6.6 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.4 3.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.4 4.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.4 3.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.4 4.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 1.5 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.4 3.4 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.4 1.1 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.4 1.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.4 1.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.4 3.2 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.3 1.7 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.3 4.7 GO:0002020 protease binding(GO:0002020)
0.3 1.3 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.3 3.3 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.3 2.9 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 2.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.3 1.2 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.3 1.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.3 1.1 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3 1.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 1.3 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.3 7.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.3 0.8 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.3 3.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 1.3 GO:0031769 glucagon receptor binding(GO:0031769)
0.3 3.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 11.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.2 1.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 2.7 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.2 0.7 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 2.2 GO:0005113 patched binding(GO:0005113)
0.2 2.6 GO:0004046 aminoacylase activity(GO:0004046)
0.2 12.8 GO:0000146 microfilament motor activity(GO:0000146)
0.2 3.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 0.7 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.2 1.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 0.4 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.2 1.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 3.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 2.2 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 0.9 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 3.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 2.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 6.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 1.2 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.2 2.0 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.2 3.6 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2 0.5 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.2 6.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 1.3 GO:0043394 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.2 0.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 2.4 GO:2001069 glycogen binding(GO:2001069)
0.2 0.8 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 2.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 2.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 3.1 GO:0042056 chemoattractant activity(GO:0042056)
0.1 3.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 1.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.4 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462)
0.1 1.0 GO:1903924 estradiol binding(GO:1903924)
0.1 0.6 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.1 34.6 GO:0030246 carbohydrate binding(GO:0030246)
0.1 1.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 2.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 1.9 GO:0005243 gap junction channel activity(GO:0005243)
0.1 1.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.6 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 2.0 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 5.9 GO:0043022 ribosome binding(GO:0043022)
0.1 0.8 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 2.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.9 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.9 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 3.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.3 GO:0030251 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.1 25.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 5.7 GO:0004601 peroxidase activity(GO:0004601)
0.1 0.7 GO:0005035 death receptor activity(GO:0005035)
0.1 0.8 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 3.2 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.1 1.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 1.2 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 2.1 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 7.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.8 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 1.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 1.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 3.5 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 3.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.4 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.1 18.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.4 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 0.6 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 0.7 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 2.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 2.1 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.1 1.1 GO:0005123 death receptor binding(GO:0005123) nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 8.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.9 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 11.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 4.4 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 11.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.6 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.8 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.7 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 1.0 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.7 GO:0005548 phospholipid transporter activity(GO:0005548)
0.1 1.3 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.1 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.1 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.9 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 0.3 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 1.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.9 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.7 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 1.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.5 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 5.4 GO:0051082 unfolded protein binding(GO:0051082)
0.1 0.6 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.7 GO:0045503 dynein light chain binding(GO:0045503)
0.1 1.2 GO:0005112 Notch binding(GO:0005112)
0.1 0.3 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 2.1 GO:0005126 cytokine receptor binding(GO:0005126)
0.1 1.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0 2.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 29.4 GO:0003779 actin binding(GO:0003779)
0.0 3.1 GO:0003823 antigen binding(GO:0003823)
0.0 3.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.6 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.8 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 17.4 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.9 GO:0099604 ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.9 GO:0008252 nucleotidase activity(GO:0008252)
0.0 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 1.1 GO:0004532 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.4 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 4.4 GO:0005179 hormone activity(GO:0005179)
0.0 1.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 1.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.4 GO:0005217 intracellular ligand-gated ion channel activity(GO:0005217) intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 2.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 4.7 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 2.1 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 1.5 GO:0005125 cytokine activity(GO:0005125)
0.0 1.3 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:0045309 protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.0 1.1 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 1.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 3.3 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 11.2 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.1 GO:0070035 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.1 GO:0016408 C-acyltransferase activity(GO:0016408)
0.0 0.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 1.3 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.3 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 2.6 GO:0008194 UDP-glycosyltransferase activity(GO:0008194)
0.0 0.1 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.0 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 1.0 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.8 7.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.6 7.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.5 0.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.5 9.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.4 18.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 0.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.4 6.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.4 10.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.4 3.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.4 15.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 2.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 2.6 PID IL23 PATHWAY IL23-mediated signaling events
0.2 3.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.2 1.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 7.8 NABA COLLAGENS Genes encoding collagen proteins
0.2 2.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.2 1.8 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.2 4.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 3.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 0.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 1.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 2.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 7.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 3.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 0.9 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 4.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.5 PID ARF6 PATHWAY Arf6 signaling events
0.1 14.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 4.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 0.9 PID FGF PATHWAY FGF signaling pathway
0.1 6.2 PID E2F PATHWAY E2F transcription factor network
0.1 1.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.1 PID ALK2 PATHWAY ALK2 signaling events
0.1 0.8 PID IL1 PATHWAY IL1-mediated signaling events
0.1 1.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 0.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 2.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 6.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 6.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 1.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
1.2 9.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.9 9.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.7 5.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.6 7.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.5 3.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.4 4.0 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.4 1.3 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.4 2.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 4.7 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.3 2.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3 1.9 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.3 3.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 3.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.3 3.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.3 3.8 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 6.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 2.5 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.2 2.4 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 2.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 4.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 11.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 1.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 3.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 4.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 2.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.2 6.4 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.2 7.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 11.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 7.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.2 3.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.7 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.1 5.4 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 2.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.9 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 0.7 REACTOME OPSINS Genes involved in Opsins
0.1 2.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 0.8 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.1 1.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 3.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 2.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 1.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 4.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 0.5 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 2.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 3.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.9 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.2 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 1.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.9 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.4 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.3 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 1.6 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.3 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway