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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for tcf12

Z-value: 2.32

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Transcription factors associated with tcf12

Gene Symbol Gene ID Gene Info
tcf12
ENSDARG00000004714 transcription factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tcf12dr11_v1_chr7_-_52709759_527099350.601.1e-10Click!

Activity profile of tcf12 motif

Sorted Z-values of tcf12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_36911118 38.27 ENSDART00000048739
trim9
tripartite motif containing 9
chr15_-_15357178 37.59 ENSDART00000106120
ywhag2
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2
chr4_-_14328997 35.41 ENSDART00000091151
nell2b
neural EGFL like 2b
chr19_+_30633453 35.30 ENSDART00000052124
fam49al
family with sequence similarity 49, member A-like
chr10_+_15777258 32.85 ENSDART00000140511
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr2_-_16565690 32.55 ENSDART00000022549
atp1b3a
ATPase Na+/K+ transporting subunit beta 3a
chr16_-_17207754 30.27 ENSDART00000063804
wu:fj39g12
wu:fj39g12
chr10_+_15777064 29.97 ENSDART00000114483
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr20_+_27020201 28.91 ENSDART00000126919
ENSDART00000016014
chga
chromogranin A
chr11_+_7324704 26.79 ENSDART00000031937
diras1a
DIRAS family, GTP-binding RAS-like 1a
chr25_-_19433244 26.53 ENSDART00000154778
map1ab
microtubule-associated protein 1Ab
chr19_+_233143 26.30 ENSDART00000175273
syngap1a
synaptic Ras GTPase activating protein 1a
chr23_+_28648864 25.51 ENSDART00000189096
l1cama
L1 cell adhesion molecule, paralog a
chr3_-_28075756 25.36 ENSDART00000122037
rbfox1
RNA binding fox-1 homolog 1
chr10_-_17745345 24.87 ENSDART00000132690
ENSDART00000135376
si:dkey-200l5.4
si:dkey-200l5.4
chr21_-_19018455 24.83 ENSDART00000080256
nefma
neurofilament, medium polypeptide a
chr9_+_34425736 24.46 ENSDART00000135147
si:ch211-218d20.15
si:ch211-218d20.15
chr11_-_101758 23.46 ENSDART00000173015
elmo2
engulfment and cell motility 2
chr1_+_59154521 23.33 ENSDART00000130089
ENSDART00000152456
soul5l
heme-binding protein soul5, like
chr14_-_33936524 22.89 ENSDART00000112438
si:ch73-335m24.5
si:ch73-335m24.5
chr7_+_26224211 22.63 ENSDART00000173999
vgf
VGF nerve growth factor inducible
chr11_+_30057762 22.32 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr16_+_39159752 22.30 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr1_-_21409877 22.07 ENSDART00000102782
gria2a
glutamate receptor, ionotropic, AMPA 2a
chr3_-_49566364 21.82 ENSDART00000161507
zgc:153426
zgc:153426
chr6_-_13308813 21.66 ENSDART00000065372
kcnj3b
potassium inwardly-rectifying channel, subfamily J, member 3b
chr1_+_8662530 21.57 ENSDART00000054989
fscn1b
fascin actin-bundling protein 1b
chr17_+_23298928 21.14 ENSDART00000153652
zgc:165461
zgc:165461
chr20_+_41549200 20.58 ENSDART00000135715
fam184a
family with sequence similarity 184, member A
chr13_-_9318891 20.44 ENSDART00000137364
si:dkey-33c12.3
si:dkey-33c12.3
chr6_+_27667359 20.39 ENSDART00000159624
ENSDART00000049177
rab6ba
RAB6B, member RAS oncogene family a
chr22_+_5106751 20.16 ENSDART00000138967
atcaya
ataxia, cerebellar, Cayman type a
chr20_+_18580176 19.97 ENSDART00000185310
si:dkeyp-72h1.1
si:dkeyp-72h1.1
chr5_-_55395964 19.75 ENSDART00000145791
prune2
prune homolog 2 (Drosophila)
chr21_+_11468934 19.70 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
grin1a
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr19_-_47526737 19.63 ENSDART00000186636
scg5
secretogranin V
chr16_-_36798783 19.38 ENSDART00000145697
calb1
calbindin 1
chr14_-_21618005 19.31 ENSDART00000043162
reep2
receptor accessory protein 2
chr13_+_40019001 19.26 ENSDART00000158820
golga7bb
golgin A7 family, member Bb
chr5_+_3501859 19.09 ENSDART00000080486
ywhag1
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr5_+_42467867 19.09 ENSDART00000172028
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr1_-_38816685 18.71 ENSDART00000075230
asb5b
ankyrin repeat and SOCS box containing 5b
chr17_-_26721007 18.69 ENSDART00000034580
calm1a
calmodulin 1a
chr2_-_36933472 18.33 ENSDART00000170405
BX470229.2

chr17_-_16069905 18.32 ENSDART00000110383
map7a
microtubule-associated protein 7a
chr13_+_27314795 18.31 ENSDART00000128726
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr2_+_34967022 17.92 ENSDART00000134926
astn1
astrotactin 1
chr14_+_22172047 17.88 ENSDART00000114750
ENSDART00000148259
gabrb2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr6_+_36942966 17.63 ENSDART00000028895
negr1
neuronal growth regulator 1
chr12_-_28881638 17.62 ENSDART00000148459
ENSDART00000039667
ENSDART00000148668
ENSDART00000136593
ENSDART00000139923
ENSDART00000148912
cbx1b
chromobox homolog 1b (HP1 beta homolog Drosophila)
chr13_+_30054996 17.39 ENSDART00000110061
ENSDART00000186045
spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr3_-_46818001 17.38 ENSDART00000166505
elavl3
ELAV like neuron-specific RNA binding protein 3
chr13_-_21688176 17.28 ENSDART00000063825
sprn
shadow of prion protein
chr14_+_35748385 17.13 ENSDART00000064617
ENSDART00000074671
ENSDART00000172803
gria2b
glutamate receptor, ionotropic, AMPA 2b
chr23_-_21453614 17.07 ENSDART00000079274
her4.1
hairy-related 4, tandem duplicate 1
chr14_+_35748206 16.99 ENSDART00000177391
gria2b
glutamate receptor, ionotropic, AMPA 2b
chr8_-_51404806 16.86 ENSDART00000060625
lgi3
leucine-rich repeat LGI family, member 3
chr8_-_4618653 16.72 ENSDART00000025535
sept5a
septin 5a
chr1_-_25911292 16.71 ENSDART00000145012
usp53b
ubiquitin specific peptidase 53b
chr8_+_24861264 16.67 ENSDART00000099607
slc6a17
solute carrier family 6 (neutral amino acid transporter), member 17
chr6_-_35472923 16.60 ENSDART00000185907
rgs8
regulator of G protein signaling 8
chr2_+_34967210 16.58 ENSDART00000141796
astn1
astrotactin 1
chr18_-_8312848 16.52 ENSDART00000092033
mapk8ip2
mitogen-activated protein kinase 8 interacting protein 2
chr19_-_5254699 16.52 ENSDART00000081951
stx1b
syntaxin 1B
chr17_-_751083 16.34 ENSDART00000188606
CABZ01102109.1

chr16_+_43152727 16.27 ENSDART00000125590
ENSDART00000154493
adam22
ADAM metallopeptidase domain 22
chr11_+_37144328 16.22 ENSDART00000162830
wnk2
WNK lysine deficient protein kinase 2
chr5_-_46896541 16.13 ENSDART00000133240
edil3a
EGF-like repeats and discoidin I-like domains 3a
chr5_+_22098591 15.89 ENSDART00000143676
zc3h12b
zinc finger CCCH-type containing 12B
chr5_-_10768258 15.89 ENSDART00000157043
rtn4r
reticulon 4 receptor
chr13_+_4405282 15.63 ENSDART00000148280
prr18
proline rich 18
chr7_+_50053339 15.63 ENSDART00000174308
LRRC4C (1 of many)
si:dkey-6l15.1
chr5_-_30088070 15.57 ENSDART00000078115
ENSDART00000134209
sdhda
succinate dehydrogenase complex, subunit D, integral membrane protein a
chr16_+_7626535 15.52 ENSDART00000182670
ENSDART00000065514
ENSDART00000150212
stx12l
syntaxin 12, like
chr23_-_30781875 15.49 ENSDART00000114628
ENSDART00000180949
ENSDART00000191313
myt1a
myelin transcription factor 1a
chr3_-_46817838 15.46 ENSDART00000028610
elavl3
ELAV like neuron-specific RNA binding protein 3
chr9_+_4609746 15.43 ENSDART00000075420
rprma
reprimo, TP53 dependent G2 arrest mediator candidate a
chr4_+_3482312 15.36 ENSDART00000109044
grm8a
glutamate receptor, metabotropic 8a
chr3_-_36115339 15.36 ENSDART00000187406
ENSDART00000123505
ENSDART00000151775
rab11fip4a
RAB11 family interacting protein 4 (class II) a
chr5_-_38384289 15.36 ENSDART00000135260
mink1
misshapen-like kinase 1
chr5_+_23118470 15.21 ENSDART00000149893
nexmifa
neurite extension and migration factor a
chr24_-_24146875 14.93 ENSDART00000173052
map7d2b
MAP7 domain containing 2b
chr19_-_7450796 14.75 ENSDART00000104750
mllt11
MLLT11, transcription factor 7 cofactor
chr19_-_6385594 14.70 ENSDART00000104950
atp1a3a
ATPase Na+/K+ transporting subunit alpha 3a
chr9_-_32753535 14.66 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr8_-_53198154 14.66 ENSDART00000083416
gabrd
gamma-aminobutyric acid (GABA) A receptor, delta
chr16_-_12984631 14.65 ENSDART00000184863
cacng7b
calcium channel, voltage-dependent, gamma subunit 7b
chr20_-_34801181 14.64 ENSDART00000048375
ENSDART00000132426
stmn4
stathmin-like 4
chr16_+_4055331 14.55 ENSDART00000128978
CR391998.1

chr13_+_51579851 14.53 ENSDART00000163847
nkx6.2
NK6 homeobox 2
chr22_+_5103349 14.53 ENSDART00000083474
atcaya
ataxia, cerebellar, Cayman type a
chr12_-_10220036 14.48 ENSDART00000134619
mpp2b
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr13_+_11439486 14.44 ENSDART00000138312
zbtb18
zinc finger and BTB domain containing 18
chr3_-_38692920 14.29 ENSDART00000155042
mpp3a
membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3)
chr6_+_59967994 14.25 ENSDART00000050457
zgc:65895
zgc:65895
chr19_+_8144556 14.23 ENSDART00000027274
ENSDART00000147218
efna3a
ephrin-A3a
chr13_+_36633355 14.18 ENSDART00000135612
si:ch211-67f24.7
si:ch211-67f24.7
chr10_-_41450367 14.15 ENSDART00000122682
ENSDART00000189549
cabp1b
calcium binding protein 1b
chr17_+_23937262 14.11 ENSDART00000113276
si:ch211-189k9.2
si:ch211-189k9.2
chr8_-_7232413 13.84 ENSDART00000092426
grip2a
glutamate receptor interacting protein 2a
chr21_+_11468642 13.80 ENSDART00000041869
grin1a
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr19_-_9711472 13.70 ENSDART00000016197
ENSDART00000175075
slc2a3a
solute carrier family 2 (facilitated glucose transporter), member 3a
chr3_-_21061931 13.65 ENSDART00000036741
fam57ba
family with sequence similarity 57, member Ba
chr8_-_4596662 13.58 ENSDART00000138199
sept5a
septin 5a
chr14_+_11103718 13.56 ENSDART00000161311
nexmifb
neurite extension and migration factor b
chr14_+_21783229 13.46 ENSDART00000170784
ankrd13d
ankyrin repeat domain 13 family, member D
chr13_+_30055171 13.44 ENSDART00000143581
ENSDART00000132027
spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr6_-_16667886 13.37 ENSDART00000180854
ENSDART00000190116
unc80
unc-80 homolog (C. elegans)
chr5_-_55395384 13.35 ENSDART00000147298
ENSDART00000082577
prune2
prune homolog 2 (Drosophila)
chr19_-_30565122 13.33 ENSDART00000185650
hpcal4
hippocalcin like 4
chr13_+_24834199 13.32 ENSDART00000101274
zgc:153981
zgc:153981
chr23_-_3674443 13.31 ENSDART00000134830
ENSDART00000057422
pacsin1a
protein kinase C and casein kinase substrate in neurons 1a
chr11_-_1291012 13.30 ENSDART00000158390
atp2b2
ATPase plasma membrane Ca2+ transporting 2
chr21_+_7823146 13.22 ENSDART00000030579
crhbp
corticotropin releasing hormone binding protein
chr19_-_13774502 13.12 ENSDART00000159711
epb41a
erythrocyte membrane protein band 4.1a
chr13_+_17702853 13.07 ENSDART00000145438
si:dkey-27m7.4
si:dkey-27m7.4
chr5_-_13766651 12.97 ENSDART00000134064
mxd1
MAX dimerization protein 1
chr16_+_45456066 12.85 ENSDART00000093365
syngap1b
synaptic Ras GTPase activating protein 1b
chr1_+_32521469 12.82 ENSDART00000113818
ENSDART00000152580
nlgn4a
neuroligin 4a
chr15_-_47937204 12.80 ENSDART00000154705
si:ch1073-111c8.3
si:ch1073-111c8.3
chr25_-_8030425 12.78 ENSDART00000014964
camk1db
calcium/calmodulin-dependent protein kinase 1Db
chr24_-_20641000 12.72 ENSDART00000166135
zbtb47b
zinc finger and BTB domain containing 47b
chr23_+_6795531 12.53 ENSDART00000092131
si:ch211-117c9.5
si:ch211-117c9.5
chr11_+_30058139 12.53 ENSDART00000112254
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr11_-_30352333 12.50 ENSDART00000030794
tmem169a
transmembrane protein 169a
chr14_-_32258759 12.49 ENSDART00000052949
fgf13a
fibroblast growth factor 13a
chr23_+_19594608 12.41 ENSDART00000134865
slmapb
sarcolemma associated protein b
chr4_+_11140197 12.40 ENSDART00000067264
cracr2ab
calcium release activated channel regulator 2Ab
chr6_+_55277419 12.35 ENSDART00000083670
CABZ01041604.1

chr14_+_14225048 12.34 ENSDART00000168749
nlgn3a
neuroligin 3a
chr21_-_41305748 12.33 ENSDART00000170457
nsg2
neuronal vesicle trafficking associated 2
chr11_+_30000814 12.30 ENSDART00000191011
ENSDART00000189770
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr14_-_30490763 12.27 ENSDART00000193166
ENSDART00000183471
ENSDART00000087859
micu3b
mitochondrial calcium uptake family, member 3b
chr15_+_28482862 12.27 ENSDART00000015286
ENSDART00000154320
ankrd13b
ankyrin repeat domain 13B
chr14_-_27121854 12.17 ENSDART00000173119
pcdh11
protocadherin 11
chr12_+_5189776 12.13 ENSDART00000081298
lgi1b
leucine-rich, glioma inactivated 1b
chr5_+_28398449 12.09 ENSDART00000165292
nsmfb
NMDA receptor synaptonuclear signaling and neuronal migration factor b
chr3_-_62380146 12.07 ENSDART00000155853
gprc5ba
G protein-coupled receptor, class C, group 5, member Ba
chr23_+_6272638 12.04 ENSDART00000190366
syt2a
synaptotagmin IIa
chr20_+_88168 12.03 ENSDART00000149283
zgc:112001
zgc:112001
chr5_+_20030414 11.96 ENSDART00000181430
ENSDART00000047841
ENSDART00000182813
sgsm1a
small G protein signaling modulator 1a
chr22_+_10215558 11.82 ENSDART00000063274
kctd6a
potassium channel tetramerization domain containing 6a
chr6_-_38418862 11.77 ENSDART00000104135
gabra5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr7_-_58130703 11.72 ENSDART00000172082
ank2b
ankyrin 2b, neuronal
chr4_+_12617108 11.70 ENSDART00000134362
ENSDART00000112860
lmo3
LIM domain only 3
chr6_-_20875111 11.66 ENSDART00000115118
ENSDART00000159916
tns1a
tensin 1a
chr19_+_32979331 11.65 ENSDART00000078066
spire1a
spire-type actin nucleation factor 1a
chr9_+_38983895 11.58 ENSDART00000144893
map2
microtubule-associated protein 2
chr23_+_21455152 11.53 ENSDART00000158511
ENSDART00000161321
ENSDART00000160731
ENSDART00000137573
her4.2
hairy-related 4, tandem duplicate 2
chr7_-_23996133 11.51 ENSDART00000173761
si:dkey-183c6.8
si:dkey-183c6.8
chr11_+_36180349 11.49 ENSDART00000012940
grm2b
glutamate receptor, metabotropic 2b
chr2_+_22702488 11.47 ENSDART00000076647
kif1ab
kinesin family member 1Ab
chr23_-_39849155 11.45 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr23_-_21463788 11.43 ENSDART00000079265
her4.4
hairy-related 4, tandem duplicate 4
chr2_+_38881165 11.43 ENSDART00000141850
carmil3
capping protein regulator and myosin 1 linker 3
chr9_-_27648683 11.40 ENSDART00000017292
stxbp5l
syntaxin binding protein 5-like
chr8_-_43158486 11.32 ENSDART00000134801
ccdc92
coiled-coil domain containing 92
chr24_-_38384432 11.22 ENSDART00000140739
lrrc4bb
leucine rich repeat containing 4Bb
chr21_+_25935845 11.22 ENSDART00000141149
caln2
calneuron 2
chr2_-_31735142 11.17 ENSDART00000130903
ralyl
RALY RNA binding protein like
chr25_-_12203952 11.16 ENSDART00000158204
ENSDART00000091727
ntrk3a
neurotrophic tyrosine kinase, receptor, type 3a
chr5_+_15667874 11.15 ENSDART00000127015
srrm4
serine/arginine repetitive matrix 4
chr5_-_23280098 11.12 ENSDART00000126540
ENSDART00000051533
plp1b
proteolipid protein 1b
chr12_-_29624638 11.12 ENSDART00000126744
nrg3b
neuregulin 3b
chr7_+_29951997 11.09 ENSDART00000173453
tpma
alpha-tropomyosin
chr15_-_26636826 11.08 ENSDART00000087632
slc47a4
solute carrier family 47 (multidrug and toxin extrusion), member 4
chr15_+_47161917 11.02 ENSDART00000167860
gap43
growth associated protein 43
chr10_-_24343507 10.99 ENSDART00000002974
pitpnab
phosphatidylinositol transfer protein, alpha b
chr2_+_22694382 10.92 ENSDART00000139196
kif1ab
kinesin family member 1Ab
chr14_-_23737674 10.92 ENSDART00000005842
fgf1a
fibroblast growth factor 1a
chr14_+_45925810 10.90 ENSDART00000189543
flrt1b
fibronectin leucine rich transmembrane protein 1b
chr3_-_22191132 10.89 ENSDART00000154226
ENSDART00000155528
ENSDART00000155190
maptb
microtubule-associated protein tau b
chr11_+_30161168 10.85 ENSDART00000157385
cdkl5
cyclin-dependent kinase-like 5
chr21_-_43952958 10.79 ENSDART00000039571
camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr23_-_18057851 10.75 ENSDART00000173075
ENSDART00000173230
ENSDART00000173135
ENSDART00000173431
ENSDART00000173068
ENSDART00000172987
zgc:92287
zgc:92287
chr20_-_37629084 10.75 ENSDART00000141734
hivep2a
human immunodeficiency virus type I enhancer binding protein 2a
chr3_+_36515376 10.72 ENSDART00000161652
si:dkeyp-72e1.9
si:dkeyp-72e1.9
chr10_+_8680730 10.71 ENSDART00000011987
isl1l
islet1, like
chr1_-_14233815 10.67 ENSDART00000044896
camk2d2
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr9_-_24050257 10.65 ENSDART00000090414
ackr3a
atypical chemokine receptor 3a
chr5_+_20148671 10.64 ENSDART00000143205
svopa
SV2 related protein a
chr25_+_35683956 10.53 ENSDART00000149768
kif21a
kinesin family member 21A
chr14_+_21783400 10.48 ENSDART00000164023
ankrd13d
ankyrin repeat domain 13 family, member D
chr18_-_5692292 10.47 ENSDART00000121503
cplx3b
complexin 3b
chr14_+_24215046 10.43 ENSDART00000079215
stc2a
stanniocalcin 2a
chr16_+_46148990 10.37 ENSDART00000083919
sv2a
synaptic vesicle glycoprotein 2A
chr5_+_42402536 10.36 ENSDART00000186754
BX548073.11

chr17_+_23938283 10.35 ENSDART00000184391
si:ch211-189k9.2
si:ch211-189k9.2
chr13_+_23157053 10.34 ENSDART00000162359
sorbs1
sorbin and SH3 domain containing 1
chr23_-_5032587 10.29 ENSDART00000163903
kcna2b
potassium voltage-gated channel, shaker-related subfamily, member 2b
chr15_+_16908085 10.25 ENSDART00000186870
ypel2b
yippee-like 2b
chr9_-_43375205 10.23 ENSDART00000138436
znf385b
zinc finger protein 385B
chr2_-_33676494 10.17 ENSDART00000141192
b4galt2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr17_-_19019635 10.15 ENSDART00000126666
flrt2
fibronectin leucine rich transmembrane protein 2
chr6_-_10320676 10.13 ENSDART00000151247
scn1lab
sodium channel, voltage-gated, type I like, alpha b
chr11_+_1845787 10.07 ENSDART00000173062
lrp1aa
low density lipoprotein receptor-related protein 1Aa
chr2_+_26237322 10.04 ENSDART00000030520
palm1b
paralemmin 1b
chr13_-_41155472 10.02 ENSDART00000160588
si:dkeyp-86d6.2
si:dkeyp-86d6.2
chr6_-_14139503 9.99 ENSDART00000089577
cacnb4b
calcium channel, voltage-dependent, beta 4b subunit
chr3_+_46724528 9.96 ENSDART00000181358
pde4a
phosphodiesterase 4A, cAMP-specific

Network of associatons between targets according to the STRING database.

First level regulatory network of tcf12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
14.0 42.1 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
7.2 28.8 GO:2000048 negative regulation of cell-substrate adhesion(GO:0010812) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
6.2 67.8 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
5.6 22.3 GO:0060074 synapse maturation(GO:0060074)
5.6 16.7 GO:0015824 proline transport(GO:0015824)
5.4 26.8 GO:0061551 trigeminal ganglion development(GO:0061551)
5.2 5.2 GO:0042478 regulation of eye photoreceptor cell development(GO:0042478)
4.8 19.4 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
4.3 17.4 GO:0021742 abducens nucleus development(GO:0021742)
4.1 16.6 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
4.1 24.8 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
3.6 10.9 GO:0010893 positive regulation of steroid biosynthetic process(GO:0010893)
3.4 10.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
3.3 16.5 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
3.3 16.3 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
3.1 71.7 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
3.1 15.6 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
3.1 9.3 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
3.0 9.1 GO:0061355 Wnt protein secretion(GO:0061355)
3.0 9.0 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
3.0 14.8 GO:0090200 regulation of mitochondrial membrane potential(GO:0051881) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
2.7 8.2 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
2.6 46.8 GO:0007158 neuron cell-cell adhesion(GO:0007158)
2.4 54.9 GO:0045773 positive regulation of axon extension(GO:0045773)
2.3 11.7 GO:0036371 protein localization to T-tubule(GO:0036371)
2.2 40.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
2.2 8.8 GO:1901380 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
2.2 41.3 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
2.2 4.3 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
2.1 8.4 GO:0090161 Golgi ribbon formation(GO:0090161)
2.1 28.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
2.0 8.2 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
2.0 6.0 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
2.0 9.9 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
1.9 7.8 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
1.9 19.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
1.7 6.9 GO:0015677 copper ion import(GO:0015677)
1.7 22.1 GO:0048899 anterior lateral line development(GO:0048899)
1.7 6.7 GO:0030307 positive regulation of cell growth(GO:0030307)
1.7 18.3 GO:0021754 facial nucleus development(GO:0021754)
1.7 5.0 GO:0010265 SCF complex assembly(GO:0010265)
1.6 6.6 GO:0033363 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
1.6 8.0 GO:0007624 ultradian rhythm(GO:0007624)
1.6 17.2 GO:0019233 sensory perception of pain(GO:0019233)
1.5 6.2 GO:1900136 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
1.5 4.5 GO:0016264 gap junction assembly(GO:0016264)
1.5 8.9 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
1.5 23.5 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
1.5 11.6 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
1.5 7.3 GO:0030327 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
1.4 4.3 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
1.4 23.0 GO:0003310 pancreatic A cell differentiation(GO:0003310)
1.4 6.9 GO:0034505 tooth mineralization(GO:0034505)
1.3 6.6 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
1.3 9.2 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
1.3 10.5 GO:0021634 optic nerve formation(GO:0021634)
1.3 6.4 GO:1903146 regulation of mitophagy(GO:1903146)
1.3 16.7 GO:0010996 response to auditory stimulus(GO:0010996)
1.3 3.8 GO:0006564 L-serine biosynthetic process(GO:0006564)
1.3 8.8 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
1.3 3.8 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
1.2 19.8 GO:1903288 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
1.2 30.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
1.2 30.0 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
1.1 6.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.1 7.6 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
1.1 3.2 GO:2001223 negative regulation of neuron migration(GO:2001223)
1.1 17.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
1.0 5.2 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
1.0 6.2 GO:0016572 histone phosphorylation(GO:0016572)
1.0 6.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
1.0 20.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
1.0 5.0 GO:0014896 muscle hypertrophy(GO:0014896)
1.0 3.0 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
1.0 3.9 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
1.0 3.0 GO:1990403 embryonic brain development(GO:1990403)
1.0 33.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
1.0 2.9 GO:0010387 COP9 signalosome assembly(GO:0010387)
1.0 2.9 GO:0051039 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
1.0 2.9 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.9 4.7 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.9 3.8 GO:0070987 error-free translesion synthesis(GO:0070987)
0.9 6.6 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.9 1.9 GO:2001222 regulation of neuron migration(GO:2001222)
0.9 11.1 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.9 4.6 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.9 4.5 GO:0090527 actin filament reorganization(GO:0090527)
0.9 4.5 GO:0016322 neuron remodeling(GO:0016322)
0.9 2.7 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.9 7.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.9 17.1 GO:1990089 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.9 21.0 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.9 4.3 GO:0046850 regulation of bone remodeling(GO:0046850)
0.9 32.0 GO:0046883 regulation of hormone secretion(GO:0046883)
0.9 8.6 GO:0098900 regulation of action potential(GO:0098900)
0.8 4.2 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.8 5.9 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.8 3.3 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.8 5.0 GO:0032486 Rap protein signal transduction(GO:0032486)
0.8 23.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.8 9.0 GO:0034394 protein localization to cell surface(GO:0034394)
0.8 4.8 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.8 4.8 GO:0048714 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.8 12.6 GO:0016198 axon choice point recognition(GO:0016198)
0.8 2.4 GO:0036076 ligamentous ossification(GO:0036076)
0.8 1.5 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.8 5.4 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.8 6.8 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.8 7.5 GO:0061709 reticulophagy(GO:0061709)
0.7 6.7 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.7 2.2 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.7 14.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.7 2.2 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.7 8.0 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.7 26.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.7 4.3 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.7 8.6 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.7 2.1 GO:1903060 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.7 9.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.7 3.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.7 13.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.7 4.9 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.7 24.5 GO:0001764 neuron migration(GO:0001764)
0.7 7.7 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.7 2.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.7 27.4 GO:0048854 brain morphogenesis(GO:0048854)
0.7 13.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.7 29.1 GO:0021854 hypothalamus development(GO:0021854)
0.7 14.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.7 6.0 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.7 11.1 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.7 0.7 GO:0061193 tongue development(GO:0043586) tongue morphogenesis(GO:0043587) taste bud development(GO:0061193) taste bud morphogenesis(GO:0061194) taste bud formation(GO:0061195)
0.7 22.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.6 5.8 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.6 5.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.6 25.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.6 7.0 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.6 6.9 GO:0003307 regulation of Wnt signaling pathway involved in heart development(GO:0003307)
0.6 1.9 GO:0035973 aggrephagy(GO:0035973)
0.6 5.6 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.6 22.8 GO:0010107 potassium ion import(GO:0010107) potassium ion import across plasma membrane(GO:1990573)
0.6 0.6 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.6 4.3 GO:0019857 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857)
0.6 20.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.6 8.5 GO:0008354 germ cell migration(GO:0008354)
0.6 4.2 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.6 4.2 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.6 1.8 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.6 2.9 GO:0051764 actin crosslink formation(GO:0051764)
0.6 1.8 GO:0060945 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) eurydendroid cell differentiation(GO:0021755) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.6 12.3 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.6 2.3 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.6 17.4 GO:0048883 neuromast primordium migration(GO:0048883) posterior lateral line neuromast primordium migration(GO:0048920)
0.6 5.8 GO:0042044 fluid transport(GO:0042044)
0.6 6.3 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.6 4.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.6 7.2 GO:0014003 oligodendrocyte development(GO:0014003)
0.6 3.3 GO:0006574 valine catabolic process(GO:0006574)
0.5 1.1 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.5 23.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.5 5.9 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.5 4.8 GO:0060036 notochord cell vacuolation(GO:0060036)
0.5 3.7 GO:0070207 protein trimerization(GO:0070206) protein homotrimerization(GO:0070207)
0.5 3.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.5 3.7 GO:0044539 very long-chain fatty acid catabolic process(GO:0042760) long-chain fatty acid import(GO:0044539)
0.5 18.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.5 16.0 GO:0055064 chloride ion homeostasis(GO:0055064)
0.5 2.0 GO:0021703 locus ceruleus development(GO:0021703)
0.5 6.8 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.5 6.2 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.5 1.4 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.5 7.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.5 8.4 GO:0030316 osteoclast differentiation(GO:0030316)
0.5 6.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.5 6.0 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.5 5.1 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.5 7.3 GO:0007631 feeding behavior(GO:0007631)
0.5 15.9 GO:0045010 actin nucleation(GO:0045010)
0.4 1.3 GO:0031338 regulation of vesicle fusion(GO:0031338) positive regulation of vesicle fusion(GO:0031340)
0.4 9.9 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.4 1.8 GO:0071871 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.4 7.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.4 4.0 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.4 1.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 4.3 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.4 6.4 GO:0051639 actin filament network formation(GO:0051639)
0.4 3.0 GO:0030728 ovulation(GO:0030728)
0.4 2.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.4 45.5 GO:0017157 regulation of exocytosis(GO:0017157)
0.4 9.1 GO:0046847 filopodium assembly(GO:0046847)
0.4 5.7 GO:0032264 IMP salvage(GO:0032264)
0.4 2.0 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.4 1.6 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508)
0.4 0.4 GO:0043393 regulation of protein binding(GO:0043393)
0.4 3.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.4 2.7 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.4 22.9 GO:0051017 actin filament bundle assembly(GO:0051017)
0.4 2.7 GO:0003348 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.4 16.0 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.4 4.9 GO:0086001 cardiac muscle cell action potential(GO:0086001)
0.4 2.6 GO:0021982 pineal gland development(GO:0021982)
0.4 9.2 GO:0006828 manganese ion transport(GO:0006828)
0.4 22.3 GO:0098661 inorganic anion transmembrane transport(GO:0098661)
0.4 10.2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.4 2.6 GO:0048240 sperm capacitation(GO:0048240)
0.4 5.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 3.6 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.4 38.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.4 2.1 GO:0043090 amino acid import(GO:0043090) L-arginine import(GO:0043091) L-amino acid import(GO:0043092) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.4 19.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.3 1.4 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.3 17.8 GO:0006821 chloride transport(GO:0006821)
0.3 2.4 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.3 18.0 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.3 18.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.3 15.4 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.3 1.4 GO:0010712 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.3 12.8 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.3 4.4 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.3 3.7 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.3 2.9 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.3 3.9 GO:0042572 retinol metabolic process(GO:0042572)
0.3 2.5 GO:0021576 hindbrain formation(GO:0021576)
0.3 0.6 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.3 1.6 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.3 2.4 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.3 12.0 GO:0032456 endocytic recycling(GO:0032456)
0.3 28.1 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.3 9.3 GO:0036269 swimming behavior(GO:0036269)
0.3 24.3 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.3 22.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.3 0.9 GO:0008344 adult locomotory behavior(GO:0008344)
0.3 8.5 GO:0016358 dendrite development(GO:0016358)
0.3 2.0 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.3 2.8 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.3 1.1 GO:0042727 flavin-containing compound metabolic process(GO:0042726) flavin-containing compound biosynthetic process(GO:0042727)
0.3 5.5 GO:0097352 autophagosome maturation(GO:0097352)
0.3 6.5 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.3 5.1 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.3 2.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.3 7.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.3 7.5 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.3 16.2 GO:0015914 phospholipid transport(GO:0015914)
0.3 3.3 GO:0006020 inositol metabolic process(GO:0006020)
0.3 2.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 1.3 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.3 29.4 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.3 1.8 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.2 1.2 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.2 1.7 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.2 0.9 GO:0009098 leucine biosynthetic process(GO:0009098)
0.2 2.4 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.2 8.2 GO:0048278 vesicle docking(GO:0048278)
0.2 27.0 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.2 11.6 GO:0021954 central nervous system neuron development(GO:0021954)
0.2 62.2 GO:0007268 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916)
0.2 1.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2 2.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.2 2.2 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2 2.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.2 2.1 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.2 7.5 GO:0030488 tRNA methylation(GO:0030488)
0.2 3.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 4.6 GO:0007286 spermatid development(GO:0007286)
0.2 4.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.2 2.9 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.2 5.0 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.2 1.0 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 2.4 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.2 2.4 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.2 4.2 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.2 3.4 GO:0061074 regulation of neural retina development(GO:0061074)
0.2 2.7 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 2.9 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.2 3.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 1.1 GO:0043901 negative regulation of multi-organism process(GO:0043901)
0.2 1.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 7.1 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.2 3.6 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.2 5.8 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.2 2.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 4.6 GO:0000187 activation of MAPK activity(GO:0000187)
0.2 11.7 GO:1902667 regulation of axon guidance(GO:1902667)
0.2 8.6 GO:0008360 regulation of cell shape(GO:0008360)
0.2 6.1 GO:0014029 neural crest formation(GO:0014029)
0.2 5.4 GO:0060914 heart formation(GO:0060914)
0.2 3.1 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.2 0.8 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 0.8 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.2 8.3 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.2 11.1 GO:0061515 myeloid cell development(GO:0061515)
0.2 5.2 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.2 2.0 GO:0035108 limb morphogenesis(GO:0035108)
0.2 2.6 GO:0006265 DNA topological change(GO:0006265)
0.2 1.1 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 1.3 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 3.1 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 1.9 GO:0000266 mitochondrial fission(GO:0000266)
0.1 4.9 GO:0009648 photoperiodism(GO:0009648)
0.1 11.0 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.1 1.1 GO:0046958 learning(GO:0007612) nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 4.5 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 15.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 6.0 GO:0044782 cilium organization(GO:0044782)
0.1 3.5 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.1 2.2 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.1 24.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 3.0 GO:0003401 axis elongation(GO:0003401)
0.1 1.9 GO:0045116 protein neddylation(GO:0045116)
0.1 0.9 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 0.9 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.6 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.1 3.4 GO:0006865 amino acid transport(GO:0006865)
0.1 25.8 GO:0007018 microtubule-based movement(GO:0007018)
0.1 0.4 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.1 0.5 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.1 17.3 GO:0043087 regulation of GTPase activity(GO:0043087)
0.1 1.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.7 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 1.5 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 1.2 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.5 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 5.1 GO:0007602 phototransduction(GO:0007602)
0.1 0.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.4 GO:0010259 multicellular organism aging(GO:0010259) G-quadruplex DNA unwinding(GO:0044806)
0.1 10.0 GO:0006909 phagocytosis(GO:0006909)
0.1 6.9 GO:0098656 anion transmembrane transport(GO:0098656)
0.1 0.8 GO:0032412 regulation of ion transmembrane transporter activity(GO:0032412)
0.1 2.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 3.4 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.1 1.6 GO:0006816 calcium ion transport(GO:0006816)
0.1 0.9 GO:0061621 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 9.7 GO:0030041 actin filament polymerization(GO:0030041)
0.1 0.6 GO:0034453 microtubule anchoring(GO:0034453)
0.1 1.0 GO:0009154 purine ribonucleotide catabolic process(GO:0009154)
0.1 0.7 GO:0045923 negative regulation of cholesterol storage(GO:0010887) positive regulation of fatty acid metabolic process(GO:0045923)
0.1 3.8 GO:0046834 lipid phosphorylation(GO:0046834)
0.1 1.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.1 19.0 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.1 0.9 GO:0035329 hippo signaling(GO:0035329)
0.1 2.1 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 7.3 GO:0006338 chromatin remodeling(GO:0006338)
0.1 0.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 7.5 GO:0016579 protein deubiquitination(GO:0016579)
0.1 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 19.1 GO:0046777 protein autophosphorylation(GO:0046777)
0.1 0.7 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.1 7.1 GO:0000209 protein polyubiquitination(GO:0000209)
0.1 0.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 1.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 0.5 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 2.0 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 2.2 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.8 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.6 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 1.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 3.7 GO:0016573 internal protein amino acid acetylation(GO:0006475) histone acetylation(GO:0016573) internal peptidyl-lysine acetylation(GO:0018393)
0.0 1.3 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 1.4 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 1.1 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.5 GO:0008345 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.2 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.2 GO:0006448 regulation of translational elongation(GO:0006448)
0.0 3.4 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 7.9 GO:0006897 endocytosis(GO:0006897)
0.0 0.6 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.4 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 1.1 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.2 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.1 GO:1904729 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.2 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 10.1 GO:0055085 transmembrane transport(GO:0055085)
0.0 0.8 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 1.3 GO:0006979 response to oxidative stress(GO:0006979)
0.0 0.2 GO:0043523 regulation of neuron apoptotic process(GO:0043523)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 17.3 GO:0032839 dendrite cytoplasm(GO:0032839)
5.0 24.8 GO:0005883 neurofilament(GO:0005883)
4.2 42.3 GO:0042583 chromaffin granule(GO:0042583)
3.1 15.6 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
2.8 28.2 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
2.8 42.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
2.8 11.0 GO:0032584 growth cone membrane(GO:0032584)
2.6 15.5 GO:0098837 postsynaptic recycling endosome(GO:0098837)
2.4 28.9 GO:0044295 axonal growth cone(GO:0044295)
2.1 27.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
2.1 22.8 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
2.0 14.2 GO:0043194 axon initial segment(GO:0043194)
2.0 12.1 GO:0070062 extracellular exosome(GO:0070062)
1.8 80.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
1.7 11.7 GO:0030315 T-tubule(GO:0030315)
1.6 21.3 GO:1990246 uniplex complex(GO:1990246)
1.5 4.4 GO:0033268 node of Ranvier(GO:0033268)
1.4 21.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
1.4 8.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
1.4 11.1 GO:0016586 RSC complex(GO:0016586)
1.3 32.4 GO:0043195 terminal bouton(GO:0043195)
1.2 21.5 GO:0005801 cis-Golgi network(GO:0005801)
1.2 11.6 GO:0070449 elongin complex(GO:0070449)
1.1 20.2 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
1.1 5.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
1.1 40.1 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
1.0 5.2 GO:0033263 CORVET complex(GO:0033263)
1.0 34.0 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
1.0 3.9 GO:0005672 transcription factor TFIIA complex(GO:0005672)
1.0 41.5 GO:0030426 growth cone(GO:0030426)
1.0 32.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.9 3.5 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.8 6.7 GO:0031931 TORC1 complex(GO:0031931)
0.8 4.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.7 5.9 GO:0097225 sperm midpiece(GO:0097225)
0.7 12.7 GO:0016363 nuclear matrix(GO:0016363)
0.7 16.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.7 5.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.7 4.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.7 11.1 GO:0043209 myelin sheath(GO:0043209)
0.7 52.2 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.7 41.1 GO:0031225 anchored component of membrane(GO:0031225)
0.6 53.8 GO:0043025 neuronal cell body(GO:0043025)
0.6 1.8 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.6 20.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.6 3.0 GO:0071203 WASH complex(GO:0071203)
0.6 4.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.6 13.3 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.6 41.0 GO:0014069 postsynaptic density(GO:0014069)
0.6 4.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.6 15.9 GO:0034707 chloride channel complex(GO:0034707)
0.6 96.5 GO:0030424 axon(GO:0030424)
0.5 8.3 GO:0031209 SCAR complex(GO:0031209)
0.5 20.4 GO:0030125 clathrin vesicle coat(GO:0030125)
0.5 9.2 GO:0005771 multivesicular body(GO:0005771)
0.4 23.3 GO:0016342 catenin complex(GO:0016342)
0.4 3.5 GO:0030666 endocytic vesicle membrane(GO:0030666) phagocytic vesicle membrane(GO:0030670)
0.4 7.7 GO:0030667 secretory granule membrane(GO:0030667)
0.4 45.2 GO:0030425 dendrite(GO:0030425)
0.4 6.7 GO:0071564 npBAF complex(GO:0071564)
0.4 100.6 GO:0043005 neuron projection(GO:0043005)
0.4 5.4 GO:0030056 hemidesmosome(GO:0030056)
0.4 1.9 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.4 6.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.4 2.1 GO:0005955 calcineurin complex(GO:0005955)
0.4 3.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.3 3.5 GO:0036449 microtubule minus-end(GO:0036449)
0.3 5.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.3 2.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.3 14.9 GO:0048786 presynaptic active zone(GO:0048786)
0.3 2.9 GO:0008180 COP9 signalosome(GO:0008180)
0.3 24.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.3 27.2 GO:0008021 synaptic vesicle(GO:0008021)
0.3 33.4 GO:0005770 late endosome(GO:0005770)
0.3 19.9 GO:0031514 motile cilium(GO:0031514)
0.3 17.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 9.4 GO:0035869 ciliary transition zone(GO:0035869)
0.2 15.2 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.2 27.4 GO:0005884 actin filament(GO:0005884)
0.2 3.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 4.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 1.7 GO:0005682 U5 snRNP(GO:0005682)
0.2 1.2 GO:0097223 sperm part(GO:0097223)
0.2 4.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 1.6 GO:0016272 prefoldin complex(GO:0016272)
0.2 1.1 GO:0016589 NURF complex(GO:0016589)
0.2 3.8 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.2 1.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 1.9 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 5.1 GO:0005844 polysome(GO:0005844)
0.2 2.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 16.7 GO:0005795 Golgi stack(GO:0005795)
0.2 28.9 GO:0005938 cell cortex(GO:0005938)
0.2 0.8 GO:0030314 junctional membrane complex(GO:0030314)
0.2 6.5 GO:0031201 SNARE complex(GO:0031201)
0.1 2.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 10.5 GO:0034703 cation channel complex(GO:0034703)
0.1 2.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.4 GO:0031213 RSF complex(GO:0031213)
0.1 0.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 4.9 GO:0005776 autophagosome(GO:0005776)
0.1 2.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.0 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 4.4 GO:0030175 filopodium(GO:0030175)
0.1 1.4 GO:1990752 microtubule end(GO:1990752)
0.1 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 29.2 GO:0005768 endosome(GO:0005768)
0.1 1.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 63.1 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.1 0.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 4.6 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 4.5 GO:0005811 lipid particle(GO:0005811)
0.1 8.3 GO:0005925 focal adhesion(GO:0005925)
0.1 3.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 2.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 19.9 GO:0005730 nucleolus(GO:0005730)
0.1 75.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 1.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.0 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.8 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 0.6 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.4 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.0 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.9 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 19.4 GO:0005499 vitamin D binding(GO:0005499)
6.2 67.8 GO:0004309 exopolyphosphatase activity(GO:0004309)
5.1 25.5 GO:0008046 axon guidance receptor activity(GO:0008046)
4.1 12.2 GO:0031716 calcitonin receptor binding(GO:0031716)
3.7 56.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
3.6 32.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
3.3 9.9 GO:0009013 succinate-semialdehyde dehydrogenase (NAD+) activity(GO:0004777) succinate-semialdehyde dehydrogenase [NAD(P)+] activity(GO:0009013)
3.0 21.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
2.8 16.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
2.7 10.9 GO:0044548 S100 protein binding(GO:0044548)
2.6 62.8 GO:0001540 beta-amyloid binding(GO:0001540)
2.4 21.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
2.2 20.1 GO:0004985 opioid receptor activity(GO:0004985)
2.1 42.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
2.1 6.2 GO:0031701 angiotensin receptor binding(GO:0031701)
2.0 12.0 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
2.0 35.4 GO:0005080 protein kinase C binding(GO:0005080)
1.9 5.8 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
1.9 17.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.8 7.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
1.7 15.6 GO:0048039 ubiquinone binding(GO:0048039)
1.7 6.9 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.6 11.5 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
1.6 8.2 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
1.6 17.9 GO:0008556 potassium-transporting ATPase activity(GO:0008556)
1.6 34.7 GO:0019894 kinesin binding(GO:0019894)
1.6 11.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
1.5 4.5 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
1.5 7.3 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
1.5 7.3 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
1.4 4.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
1.4 12.9 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
1.4 28.2 GO:0001671 ATPase activator activity(GO:0001671)
1.4 9.5 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
1.3 6.6 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
1.3 18.4 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
1.3 3.9 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
1.3 11.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.2 5.0 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
1.2 45.9 GO:0019003 GDP binding(GO:0019003)
1.2 19.8 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
1.2 17.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
1.2 8.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.2 4.7 GO:0008384 IkappaB kinase activity(GO:0008384)
1.1 9.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.1 6.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
1.1 6.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
1.1 7.5 GO:0035173 histone kinase activity(GO:0035173)
1.1 28.8 GO:0017080 sodium channel regulator activity(GO:0017080)
1.0 6.2 GO:0008502 melatonin receptor activity(GO:0008502)
1.0 8.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
1.0 29.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.9 8.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.9 44.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.9 11.0 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.9 16.9 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.9 2.6 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.8 5.9 GO:0004995 tachykinin receptor activity(GO:0004995)
0.8 4.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.8 6.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.8 3.2 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.8 15.2 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.8 11.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.8 7.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.8 15.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.8 10.1 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.8 15.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.8 3.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.8 3.8 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.7 3.7 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.7 11.9 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.7 11.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.7 9.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.7 2.2 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.7 11.7 GO:0048495 Roundabout binding(GO:0048495)
0.7 8.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.7 2.1 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.7 15.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.7 10.2 GO:0038191 neuropilin binding(GO:0038191)
0.7 5.4 GO:0008410 CoA-transferase activity(GO:0008410)
0.7 11.4 GO:0045159 myosin II binding(GO:0045159)
0.7 32.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.7 6.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.6 5.7 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.6 2.5 GO:0033149 FFAT motif binding(GO:0033149)
0.6 16.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.6 12.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.6 4.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.6 20.3 GO:0051020 GTPase binding(GO:0051020)
0.6 27.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.6 3.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.6 1.8 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.6 9.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.6 4.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.6 10.7 GO:0015026 coreceptor activity(GO:0015026)
0.6 29.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.6 2.2 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.6 13.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.5 6.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.5 15.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.5 12.5 GO:0015298 solute:cation antiporter activity(GO:0015298)
0.5 3.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.5 5.7 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 7.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.5 7.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.5 4.5 GO:0032977 membrane insertase activity(GO:0032977)
0.5 2.5 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.5 6.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.5 9.5 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.5 12.0 GO:0030371 translation repressor activity(GO:0030371)
0.5 16.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.5 6.8 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.5 13.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.5 16.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.5 1.9 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.4 7.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.4 144.4 GO:0008017 microtubule binding(GO:0008017)
0.4 28.0 GO:0051427 hormone receptor binding(GO:0051427)
0.4 2.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.4 9.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 2.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.4 9.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.4 2.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.4 3.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.4 5.4 GO:0030506 ankyrin binding(GO:0030506)
0.4 6.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4 5.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.4 1.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.4 1.9 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.4 4.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.4 2.1 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.4 8.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.4 2.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.3 4.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.3 2.4 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.3 23.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.3 8.0 GO:0017046 peptide hormone binding(GO:0017046)
0.3 3.5 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.3 117.0 GO:0003924 GTPase activity(GO:0003924)
0.3 1.6 GO:0035197 siRNA binding(GO:0035197)
0.3 2.5 GO:0035591 signaling adaptor activity(GO:0035591)
0.3 15.5 GO:0045499 chemorepellent activity(GO:0045499)
0.3 19.4 GO:0030276 clathrin binding(GO:0030276)
0.3 3.1 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.3 3.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.3 2.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.3 16.3 GO:0005178 integrin binding(GO:0005178)
0.3 2.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 7.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.3 2.1 GO:0015232 heme transporter activity(GO:0015232)
0.3 2.4 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.2 5.7 GO:0015926 glucosidase activity(GO:0015926)
0.2 47.6 GO:0015293 symporter activity(GO:0015293)
0.2 1.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 10.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.2 0.7 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 2.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 31.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.2 0.9 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 6.4 GO:0015248 sterol transporter activity(GO:0015248)
0.2 84.1 GO:0005096 GTPase activator activity(GO:0005096)
0.2 1.9 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 1.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 2.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 5.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 3.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.2 7.5 GO:0032452 histone demethylase activity(GO:0032452)
0.2 0.9 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.2 3.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 17.8 GO:0045296 cadherin binding(GO:0045296)
0.2 1.5 GO:0030274 LIM domain binding(GO:0030274)
0.2 0.8 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.2 9.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 2.7 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 4.7 GO:0008378 galactosyltransferase activity(GO:0008378)
0.2 8.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 5.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 9.7 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.2 12.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.2 7.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 11.2 GO:0004521 endoribonuclease activity(GO:0004521)
0.2 11.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 10.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.2 13.9 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.2 3.9 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.2 0.8 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 1.3 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 3.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 6.1 GO:0019905 syntaxin binding(GO:0019905)
0.1 1.8 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.1 4.7 GO:0004707 MAP kinase activity(GO:0004707)
0.1 11.6 GO:0005179 hormone activity(GO:0005179)
0.1 9.5 GO:0005516 calmodulin binding(GO:0005516)
0.1 1.0 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 1.3 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1 6.9 GO:0015631 tubulin binding(GO:0015631)
0.1 2.4 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 4.8 GO:0030674 protein binding, bridging(GO:0030674)
0.1 2.9 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 4.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 5.9 GO:0051287 NAD binding(GO:0051287)
0.1 5.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 5.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.3 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.1 0.3 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.1 0.9 GO:0017136 histone deacetylase activity(GO:0004407) NAD-dependent histone deacetylase activity(GO:0017136) histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) NAD-dependent protein deacetylase activity(GO:0034979)
0.1 0.6 GO:0035198 miRNA binding(GO:0035198)
0.1 3.3 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 3.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.9 GO:0097602 cullin family protein binding(GO:0097602)
0.1 3.8 GO:0003684 damaged DNA binding(GO:0003684)
0.1 1.4 GO:0031386 protein tag(GO:0031386)
0.1 1.0 GO:0043495 protein anchor(GO:0043495)
0.1 0.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 5.5 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 2.4 GO:0035064 methylated histone binding(GO:0035064)
0.1 2.8 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 3.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.5 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.1 1.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 3.6 GO:0071949 FAD binding(GO:0071949)
0.1 0.5 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 4.4 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 2.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0008312 7S RNA binding(GO:0008312)
0.0 3.7 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.2 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.5 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 1.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 9.3 GO:0003682 chromatin binding(GO:0003682)
0.0 1.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 5.0 GO:0005261 cation channel activity(GO:0005261)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.9 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 15.7 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.8 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0005452 inorganic anion exchanger activity(GO:0005452)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.8 16.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.8 4.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.8 10.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.8 32.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.6 19.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.6 18.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.6 8.1 PID CONE PATHWAY Visual signal transduction: Cones
0.5 8.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.4 7.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.4 3.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.4 9.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.4 4.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.4 11.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 14.2 PID LKB1 PATHWAY LKB1 signaling events
0.3 5.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 5.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 4.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.2 2.6 PID REELIN PATHWAY Reelin signaling pathway
0.2 6.6 PID INSULIN PATHWAY Insulin Pathway
0.2 1.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 2.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 5.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 3.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 3.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 3.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 10.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 1.6 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 4.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 2.4 PID MYC PATHWAY C-MYC pathway
0.1 0.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 8.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.3 PID RB 1PATHWAY Regulation of retinoblastoma protein

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.8 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
2.5 37.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.2 16.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
1.2 16.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
1.0 4.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.9 17.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.8 11.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.7 4.4 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.7 7.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.7 8.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.7 7.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.6 5.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.6 6.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.6 6.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.6 13.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.6 8.9 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.5 10.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.5 8.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.5 7.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.5 4.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.5 11.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.4 3.0 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.4 9.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.4 2.5 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.4 3.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 3.3 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.3 6.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.2 26.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.2 3.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 0.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.2 1.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 5.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 2.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 4.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 8.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 5.9 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.2 2.8 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.2 13.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 3.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 3.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 7.0 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 2.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 21.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.9 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 3.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.0 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.1 0.5 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.4 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing