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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for tcf7l1a+tcf7l1b+tcf7l2

Z-value: 1.44

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Transcription factors associated with tcf7l1a+tcf7l1b+tcf7l2

Gene Symbol Gene ID Gene Info
tcf7l2
ENSDARG00000004415 transcription factor 7 like 2
tcf7l1b
ENSDARG00000007369 transcription factor 7 like 1b
tcf7l1a
ENSDARG00000038159 transcription factor 7 like 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tcf7l2dr11_v1_chr12_-_31012741_310127410.781.3e-20Click!
tcf7l1bdr11_v1_chr8_-_52229462_522294620.339.9e-04Click!
tcf7l1adr11_v1_chr10_-_42237304_42237304-0.214.5e-02Click!

Activity profile of tcf7l1a+tcf7l1b+tcf7l2 motif

Sorted Z-values of tcf7l1a+tcf7l1b+tcf7l2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_39011514 33.85 ENSDART00000075123
pcp4a
Purkinje cell protein 4a
chr14_+_22172047 21.52 ENSDART00000114750
ENSDART00000148259
gabrb2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr2_-_30784198 21.21 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr1_-_29045426 19.95 ENSDART00000019770
gpm6ba
glycoprotein M6Ba
chr17_+_27176243 19.20 ENSDART00000162527
si:ch211-160f23.7
si:ch211-160f23.7
chr17_-_20897250 17.56 ENSDART00000088106
ank3b
ankyrin 3b
chr7_+_27977065 16.46 ENSDART00000089574
tub
tubby bipartite transcription factor
chr16_+_32559821 15.99 ENSDART00000093250
pou3f2b
POU class 3 homeobox 2b
chr20_-_9436521 15.88 ENSDART00000133000
zgc:101840
zgc:101840
chr19_+_31771270 15.63 ENSDART00000147474
stmn2b
stathmin 2b
chr22_-_21150845 15.59 ENSDART00000027345
tmem59l
transmembrane protein 59-like
chr25_-_19395476 15.37 ENSDART00000182622
map1ab
microtubule-associated protein 1Ab
chr9_+_7548533 14.67 ENSDART00000081543
ptprna
protein tyrosine phosphatase, receptor type, Na
chr20_+_22666548 14.21 ENSDART00000147520
lnx1
ligand of numb-protein X 1
chr4_+_10366532 14.17 ENSDART00000189901
kcnd2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr13_-_31441042 14.10 ENSDART00000076571
rtn1a
reticulon 1a
chr24_+_32411753 14.05 ENSDART00000058530
neurod6a
neuronal differentiation 6a
chr20_+_41549200 13.90 ENSDART00000135715
fam184a
family with sequence similarity 184, member A
chr25_+_21829777 13.38 ENSDART00000027393
ckmt1
creatine kinase, mitochondrial 1
chr15_-_12545683 13.20 ENSDART00000162807
scn2b
sodium channel, voltage-gated, type II, beta
chr1_-_42779075 13.11 ENSDART00000133917
lrrtm1
leucine rich repeat transmembrane neuronal 1
chr20_-_40451115 12.92 ENSDART00000075092
pkib
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr18_-_34143189 12.48 ENSDART00000079341
plch1
phospholipase C, eta 1
chr15_+_40188076 12.29 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr6_-_15604157 11.90 ENSDART00000141597
lrrfip1b
leucine rich repeat (in FLII) interacting protein 1b
chr12_+_40905427 11.89 ENSDART00000170526
ENSDART00000185771
ENSDART00000193945
CDH18
cadherin 18
chr16_+_39159752 11.80 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr24_-_32408404 11.56 ENSDART00000144157
si:ch211-56a11.2
si:ch211-56a11.2
chr23_-_26077038 11.48 ENSDART00000126299
gdi1
GDP dissociation inhibitor 1
chr5_-_22082918 11.24 ENSDART00000020908
zc4h2
zinc finger, C4H2 domain containing
chr1_-_8428736 10.80 ENSDART00000138435
ENSDART00000121823
syngr3b
synaptogyrin 3b
chr8_+_36803415 10.76 ENSDART00000111680
iqsec2b
IQ motif and Sec7 domain 2b
chr15_+_6109861 10.31 ENSDART00000185154
PCP4 (1 of many)
Purkinje cell protein 4
chr1_-_42778510 10.30 ENSDART00000190172
lrrtm1
leucine rich repeat transmembrane neuronal 1
chr24_+_15897717 10.24 ENSDART00000105956
neto1l
neuropilin (NRP) and tolloid (TLL)-like 1, like
chr13_+_27073901 10.20 ENSDART00000146227
slc24a3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr2_-_34483597 10.10 ENSDART00000133224
brinp2
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr1_+_32528097 9.94 ENSDART00000128317
nlgn4a
neuroligin 4a
chr2_-_22230326 9.92 ENSDART00000127810
fam110b
family with sequence similarity 110, member B
chr3_-_19091024 9.85 ENSDART00000188485
ENSDART00000110554
grin2ca
glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca
chr6_-_53143667 9.84 ENSDART00000079694
gnai2b
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr19_+_29798064 9.68 ENSDART00000167803
ENSDART00000051804
marcksl1b
MARCKS-like 1b
chr14_+_22591624 9.50 ENSDART00000108987
gfra4b
GDNF family receptor alpha 4b
chr8_-_34052019 9.26 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pbx3b
pre-B-cell leukemia homeobox 3b
chr16_+_39146696 9.24 ENSDART00000121756
ENSDART00000084381
sybu
syntabulin (syntaxin-interacting)
chr4_+_69619 9.21 ENSDART00000164425
mansc1
MANSC domain containing 1
chr9_-_12034444 9.09 ENSDART00000038651
znf804a
zinc finger protein 804A
chr17_-_20897407 8.90 ENSDART00000149481
ank3b
ankyrin 3b
chr20_+_30445971 8.88 ENSDART00000153150
myt1la
myelin transcription factor 1-like, a
chr25_+_26921480 8.86 ENSDART00000155949
grm8b
glutamate receptor, metabotropic 8b
chr17_-_8638713 8.83 ENSDART00000148971
ctbp2a
C-terminal binding protein 2a
chr20_+_36234335 8.81 ENSDART00000193484
ENSDART00000181664
cnih3
cornichon family AMPA receptor auxiliary protein 3
chr18_+_16330720 8.78 ENSDART00000080638
nts
neurotensin
chr12_-_31103187 8.54 ENSDART00000005562
ENSDART00000031408
ENSDART00000125046
ENSDART00000009237
ENSDART00000122972
ENSDART00000153068
tcf7l2
transcription factor 7 like 2
chr25_+_7229046 8.53 ENSDART00000149965
ENSDART00000041820
lingo1a
leucine rich repeat and Ig domain containing 1a
chr2_-_30784502 8.51 ENSDART00000056735
rgs20
regulator of G protein signaling 20
chr1_+_49814461 8.42 ENSDART00000132405
lef1
lymphoid enhancer-binding factor 1
chr6_-_26559921 8.28 ENSDART00000104532
sox14
SRY (sex determining region Y)-box 14
chr7_-_30087048 8.08 ENSDART00000112743
nmbb
neuromedin Bb
chr3_-_30861177 8.07 ENSDART00000154811
shank1
SH3 and multiple ankyrin repeat domains 1
chr8_+_14778292 7.99 ENSDART00000089971
cacna1ea
calcium channel, voltage-dependent, R type, alpha 1E subunit a
chr15_+_22722684 7.97 ENSDART00000156760
grik4
glutamate receptor, ionotropic, kainate 4
chr15_+_28106498 7.96 ENSDART00000041707
unc119a
unc-119 homolog a (C. elegans)
chr11_+_14622379 7.85 ENSDART00000112589
efna2b
ephrin-A2b
chr15_-_2188332 7.55 ENSDART00000138941
ENSDART00000009564
shox2
short stature homeobox 2
chr21_-_17482465 7.52 ENSDART00000004548
barhl1b
BarH-like homeobox 1b
chr21_-_25522906 7.50 ENSDART00000110923
cnksr2b
connector enhancer of kinase suppressor of Ras 2b
chr6_-_57938043 7.49 ENSDART00000171073
tox2
TOX high mobility group box family member 2
chr23_+_16620801 7.37 ENSDART00000189859
ENSDART00000184578
snphb
syntaphilin b
chr15_+_24691088 7.35 ENSDART00000110618
LRRC75A
si:dkey-151p21.7
chr18_+_10907999 7.29 ENSDART00000133555
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr15_-_10341048 7.27 ENSDART00000171013
tenm4
teneurin transmembrane protein 4
chr9_-_3671911 7.13 ENSDART00000102900
sp5a
Sp5 transcription factor a
chr5_-_18474486 7.05 ENSDART00000090580
si:dkey-215k6.1
si:dkey-215k6.1
chr21_-_31241254 6.98 ENSDART00000065365
tpst1l
tyrosylprotein sulfotransferase 1, like
chr5_+_60590796 6.81 ENSDART00000159859
tmem132e
transmembrane protein 132E
chr8_-_34051548 6.78 ENSDART00000105204
pbx3b
pre-B-cell leukemia homeobox 3b
chr9_-_35155089 6.69 ENSDART00000077901
appb
amyloid beta (A4) precursor protein b
chr13_+_4505232 6.64 ENSDART00000007500
ENSDART00000161684
pde10a
phosphodiesterase 10A
chr6_-_53144336 6.62 ENSDART00000154429
gnai2b
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr17_-_4245311 6.58 ENSDART00000055379
gdf3
growth differentiation factor 3
chr23_-_20764227 6.45 ENSDART00000089750
znf362b
zinc finger protein 362b
chr16_+_17389116 6.43 ENSDART00000103750
ENSDART00000173448
fam131bb
family with sequence similarity 131, member Bb
chr2_+_33368414 6.40 ENSDART00000077462
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr3_-_55650771 6.29 ENSDART00000162413
axin2
axin 2 (conductin, axil)
chr20_-_48485354 6.24 ENSDART00000124040
ENSDART00000148437
insm1a
insulinoma-associated 1a
chr23_-_18057270 6.21 ENSDART00000173385
zgc:92287
zgc:92287
chr21_-_37889727 6.17 ENSDART00000163612
ENSDART00000180958
gabrb4
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr6_-_15603675 6.15 ENSDART00000143502
lrrfip1b
leucine rich repeat (in FLII) interacting protein 1b
chr17_+_26611929 6.14 ENSDART00000166450
ENSDART00000087023
ttc7b
tetratricopeptide repeat domain 7B
chr6_-_21616659 6.04 ENSDART00000074256
ppp1r12c
protein phosphatase 1, regulatory subunit 12C
chr5_+_44190974 5.93 ENSDART00000182634
ENSDART00000190626
TMEM8B
si:dkey-84j12.1
chr9_+_28693592 5.89 ENSDART00000110198
zgc:162780
zgc:162780
chr1_+_2190714 5.89 ENSDART00000132126
mbnl2
muscleblind-like splicing regulator 2
chr12_+_10115964 5.65 ENSDART00000152369
si:dkeyp-118b1.2
si:dkeyp-118b1.2
chr1_+_26356360 5.60 ENSDART00000113020
tet2
tet methylcytosine dioxygenase 2
chr7_+_57836841 5.54 ENSDART00000136175
camk2d1
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
chr3_-_32299892 5.40 ENSDART00000181472
si:dkey-16p21.7
si:dkey-16p21.7
chr1_-_26023678 5.28 ENSDART00000054202
si:ch211-145b13.5
si:ch211-145b13.5
chr11_+_34522554 5.23 ENSDART00000109833
zmat3
zinc finger, matrin-type 3
chr14_-_47963115 5.22 ENSDART00000003826
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr21_-_25722834 5.11 ENSDART00000101208
abhd11
abhydrolase domain containing 11
chr15_-_31588162 5.11 ENSDART00000153598
hsph1
heat shock 105/110 protein 1
chr14_+_24277556 5.05 ENSDART00000122660
hnrnpa0a
heterogeneous nuclear ribonucleoprotein A0a
chr1_+_26356205 4.96 ENSDART00000190064
ENSDART00000176380
tet2
tet methylcytosine dioxygenase 2
chr9_+_10014817 4.95 ENSDART00000132065
nxph2a
neurexophilin 2a
chr17_-_50010121 4.91 ENSDART00000122747
tmem30aa
transmembrane protein 30Aa
chr21_+_25068215 4.90 ENSDART00000167523
ENSDART00000189259
dixdc1b
DIX domain containing 1b
chr7_-_37622370 4.86 ENSDART00000173523
nkd1
naked cuticle homolog 1 (Drosophila)
chr13_+_4505079 4.82 ENSDART00000144312
pde10a
phosphodiesterase 10A
chr11_-_18604317 4.65 ENSDART00000182081
zmynd8
zinc finger, MYND-type containing 8
chr24_-_6546479 4.64 ENSDART00000160538
arhgap21a
Rho GTPase activating protein 21a
chr3_+_28831622 4.60 ENSDART00000184130
ENSDART00000191294
flr
fleer
chr10_-_31562695 4.59 ENSDART00000186456
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr11_+_28107632 4.54 ENSDART00000177721
nmur3
neuromedin U receptor 3
chr7_-_31940590 4.53 ENSDART00000131009
bdnf
brain-derived neurotrophic factor
chr7_-_42206720 4.46 ENSDART00000110907
itfg1
integrin alpha FG-GAP repeat containing 1
chr4_-_2036620 4.31 ENSDART00000150490
si:dkey-97m3.1
si:dkey-97m3.1
chr1_+_49814942 4.26 ENSDART00000164936
lef1
lymphoid enhancer-binding factor 1
chr3_-_33573252 4.20 ENSDART00000191339
ENSDART00000184612
ENSDART00000187232
ENSDART00000190671
CR847537.1

chr19_-_8880688 4.15 ENSDART00000039629
celf3a
cugbp, Elav-like family member 3a
chr24_+_11105786 4.12 ENSDART00000175182
prlh2
prolactin releasing hormone 2
chr10_+_11309814 4.03 ENSDART00000145673
si:ch211-126i22.5
si:ch211-126i22.5
chr2_+_9822319 4.02 ENSDART00000144078
ENSDART00000144371
anxa13l
annexin A13, like
chr7_-_34062301 3.97 ENSDART00000052404
map2k5
mitogen-activated protein kinase kinase 5
chr15_-_163586 3.94 ENSDART00000163597
SEPT4
septin-4
chr22_-_16042243 3.93 ENSDART00000062633
s1pr1
sphingosine-1-phosphate receptor 1
chr21_-_40782393 3.93 ENSDART00000075808
apbb3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr3_-_55650417 3.91 ENSDART00000171441
axin2
axin 2 (conductin, axil)
chr19_-_44801918 3.89 ENSDART00000108507
CSMD3 (1 of many)
si:ch211-233f16.1
chr22_-_22242884 3.83 ENSDART00000020937
hdgfl2
HDGF like 2
chr3_-_56569968 3.81 ENSDART00000165317
SMIM10
Danio rerio uncharacterized LOC797202 (LOC797202), mRNA.
chr2_-_42396592 3.76 ENSDART00000127136
slco5a1b
solute carrier organic anion transporter family member 5A1b
chr8_+_17009199 3.72 ENSDART00000139452
pde4d
phosphodiesterase 4D, cAMP-specific
chr12_+_35203091 3.67 ENSDART00000153022
ndst2b
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b
chr9_-_28990649 3.63 ENSDART00000078823
ptpn4a
protein tyrosine phosphatase, non-receptor type 4a
chr20_-_9194257 3.63 ENSDART00000133012
ylpm1
YLP motif containing 1
chr6_+_15762647 3.62 ENSDART00000127133
ENSDART00000128939
iqca1
IQ motif containing with AAA domain 1
chr21_-_20328375 3.58 ENSDART00000079593
slc26a1
solute carrier family 26 (anion exchanger), member 1
chr1_+_17376922 3.57 ENSDART00000145068
fat1a
FAT atypical cadherin 1a
chr3_+_15773991 3.56 ENSDART00000089923
znf652
zinc finger protein 652
chr19_-_8732037 3.50 ENSDART00000138971
si:ch211-39a7.1
si:ch211-39a7.1
chr13_+_28702104 3.48 ENSDART00000135481
si:ch211-67n3.9
si:ch211-67n3.9
chr19_-_9522548 3.47 ENSDART00000045245
ing4
inhibitor of growth family, member 4
chr6_-_14038804 3.46 ENSDART00000184606
ENSDART00000184609
etv5b
ets variant 5b
chr12_-_31995840 3.35 ENSDART00000112881
grin2cb
glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb
chr1_-_36151377 3.34 ENSDART00000037516
znf827
zinc finger protein 827
chr13_+_15656042 3.29 ENSDART00000134240
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr16_-_18702249 3.25 ENSDART00000191595
fhod3b
formin homology 2 domain containing 3b
chr17_-_24714837 3.24 ENSDART00000154871
si:ch211-15d5.11
si:ch211-15d5.11
chr9_+_10014514 3.23 ENSDART00000185590
nxph2a
neurexophilin 2a
chr7_-_72423666 3.20 ENSDART00000191214
rph3ab
rabphilin 3A homolog (mouse), b
chr19_-_10043142 3.19 ENSDART00000193016
grin2da
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a
chr17_-_17759138 3.17 ENSDART00000157128
ENSDART00000123845
adck1
aarF domain containing kinase 1
chr9_-_28399071 3.15 ENSDART00000104317
ENSDART00000064343
klf7b
Kruppel-like factor 7b
chr18_+_17959681 3.13 ENSDART00000142700
znf423
zinc finger protein 423
chr17_+_3379673 3.02 ENSDART00000176354
sntg2
syntrophin, gamma 2
chr2_-_43083749 2.98 ENSDART00000084303
ENSDART00000145494
kcnq3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr22_+_39058269 2.86 ENSDART00000113362
ip6k1
inositol hexakisphosphate kinase 1
chr21_-_25522510 2.81 ENSDART00000162711
cnksr2b
connector enhancer of kinase suppressor of Ras 2b
chr16_+_16933002 2.81 ENSDART00000173163
myh14
myosin, heavy chain 14, non-muscle
chr19_+_42469058 2.80 ENSDART00000076915
si:dkey-166k12.1
si:dkey-166k12.1
chr9_+_32431666 2.75 ENSDART00000187614
plcl1
phospholipase C like 1
chr23_+_2714949 2.68 ENSDART00000105284
ncoa6
nuclear receptor coactivator 6
chr11_+_26604224 2.68 ENSDART00000030453
ENSDART00000168895
ENSDART00000159505
dynlrb1
dynein, light chain, roadblock-type 1
chr11_-_23314242 2.60 ENSDART00000182394
kiss1
KiSS-1 metastasis-suppressor
chr4_-_77432218 2.60 ENSDART00000158683
slco1d1
solute carrier organic anion transporter family, member 1D1
chr24_-_35269991 2.58 ENSDART00000185424
sntg1
syntrophin, gamma 1
chr8_+_16407884 2.58 ENSDART00000133742
cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr20_-_38787341 2.53 ENSDART00000136771
dnajc5ga
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr15_+_1705167 2.49 ENSDART00000081940
otol1b
otolin 1b
chr4_-_20511595 2.47 ENSDART00000185806
rassf8b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8b
chr19_-_10207103 2.42 ENSDART00000151629
znf865
zinc finger protein 865
chr8_-_51753604 2.41 ENSDART00000007090
tbx16
T-box 16
chr20_-_43723860 2.39 ENSDART00000122051
mixl1
Mix paired-like homeobox
chr1_-_39976492 2.39 ENSDART00000181680
stox2a
storkhead box 2a
chr25_-_19395156 2.38 ENSDART00000155335
map1ab
microtubule-associated protein 1Ab
chr13_+_28732101 2.35 ENSDART00000015773
ldb1a
LIM domain binding 1a
chr14_-_32089117 2.28 ENSDART00000158014
si:ch211-69b22.5
si:ch211-69b22.5
chr6_-_29105727 2.25 ENSDART00000184355
fam69ab
family with sequence similarity 69, member Ab
chr16_-_31452416 2.22 ENSDART00000140880
ENSDART00000008297
ENSDART00000147373
csnk2a1
casein kinase 2, alpha 1 polypeptide
chr24_-_24848612 2.22 ENSDART00000190941
crhb
corticotropin releasing hormone b
chr5_-_24333684 2.13 ENSDART00000051553
znf703
zinc finger protein 703
chr6_+_6662479 2.08 ENSDART00000065568
zgc:113227
zgc:113227
chr4_-_16658514 2.08 ENSDART00000133837
dennd5b
DENN/MADD domain containing 5B
chr19_-_23895839 2.08 ENSDART00000174834
si:dkey-222b8.4
si:dkey-222b8.4
chr5_+_26156079 2.06 ENSDART00000088141
ankrd34bb
ankyrin repeat domain 34Bb
chr18_+_45796096 2.03 ENSDART00000087070
abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr15_-_30714130 2.02 ENSDART00000156914
ENSDART00000154714
msi2b
musashi RNA-binding protein 2b
chr7_-_37622153 2.00 ENSDART00000052379
nkd1
naked cuticle homolog 1 (Drosophila)
chr16_-_29194517 1.99 ENSDART00000046114
ENSDART00000148899
mef2d
myocyte enhancer factor 2d
chr19_-_32487469 1.96 ENSDART00000050130
gmpr
guanosine monophosphate reductase
chr13_-_50614639 1.93 ENSDART00000170527
vent
ventral expressed homeobox
chr7_+_42206543 1.89 ENSDART00000112543
phkb
phosphorylase kinase, beta
chr3_-_29968015 1.87 ENSDART00000077119
ENSDART00000139310
bcat2
branched chain amino-acid transaminase 2, mitochondrial
chr2_-_59376735 1.80 ENSDART00000193624
ftr38
finTRIM family, member 38
chr8_-_50346246 1.74 ENSDART00000025008
stc1
stanniocalcin 1
chr20_-_38787047 1.72 ENSDART00000152913
ENSDART00000153430
dnajc5ga
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr17_-_4245902 1.71 ENSDART00000151851
gdf3
growth differentiation factor 3
chr17_-_49443399 1.64 ENSDART00000155293
cga
glycoprotein hormones, alpha polypeptide

Network of associatons between targets according to the STRING database.

First level regulatory network of tcf7l1a+tcf7l1b+tcf7l2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 20.0 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
5.3 21.0 GO:0060074 synapse maturation(GO:0060074)
2.5 12.7 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
2.3 11.5 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
2.1 8.5 GO:0010226 response to lithium ion(GO:0010226)
1.9 11.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.8 16.5 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
1.7 6.9 GO:0042306 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
1.7 8.3 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
1.6 6.4 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
1.5 10.6 GO:0019857 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857)
1.5 7.4 GO:0051659 maintenance of mitochondrion location(GO:0051659)
1.5 7.3 GO:0032289 central nervous system myelin formation(GO:0032289)
1.3 3.9 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
1.3 13.0 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
1.3 8.8 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
1.0 3.1 GO:0010893 positive regulation of steroid biosynthetic process(GO:0010893)
1.0 13.4 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
1.0 10.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
1.0 8.0 GO:1900186 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.9 3.6 GO:0019532 oxalate transport(GO:0019532)
0.9 7.0 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.9 16.4 GO:0060079 excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
0.8 2.4 GO:0048389 intermediate mesoderm development(GO:0048389)
0.8 10.2 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.7 2.2 GO:0035902 response to immobilization stress(GO:0035902)
0.7 17.7 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.6 4.6 GO:0036372 opsin transport(GO:0036372)
0.6 12.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.5 8.1 GO:0046887 positive regulation of hormone secretion(GO:0046887)
0.5 1.9 GO:0009098 leucine biosynthetic process(GO:0009098)
0.4 8.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.4 2.5 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.4 10.2 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.4 5.6 GO:0016199 axon midline choice point recognition(GO:0016199)
0.4 3.1 GO:0021634 optic nerve formation(GO:0021634)
0.4 7.9 GO:0030316 osteoclast differentiation(GO:0030316)
0.4 4.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 16.7 GO:0061512 protein localization to cilium(GO:0061512)
0.3 2.7 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.3 3.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3 11.2 GO:0048665 neuron fate specification(GO:0048665)
0.3 2.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 1.2 GO:0032801 receptor catabolic process(GO:0032801)
0.3 0.9 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.3 11.6 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.3 3.5 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.3 9.2 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.3 2.9 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.3 2.1 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.3 11.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 1.0 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.2 1.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 2.6 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.2 4.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 7.1 GO:0021854 hypothalamus development(GO:0021854)
0.2 4.5 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.2 2.0 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.2 8.5 GO:0031103 axon regeneration(GO:0031103)
0.2 3.6 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.2 3.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 1.1 GO:1902267 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.2 1.3 GO:0050975 sensory perception of touch(GO:0050975)
0.2 1.4 GO:0042554 superoxide anion generation(GO:0042554)
0.2 0.5 GO:1903961 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) regulation of organic acid transport(GO:0032890) positive regulation of organic acid transport(GO:0032892) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transport(GO:1903793) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.2 0.8 GO:0010586 miRNA metabolic process(GO:0010586)
0.2 0.5 GO:0000212 meiotic spindle organization(GO:0000212)
0.2 2.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 14.0 GO:0050769 positive regulation of neurogenesis(GO:0050769)
0.1 22.3 GO:0048675 axon extension(GO:0048675)
0.1 4.9 GO:0045332 phospholipid translocation(GO:0045332)
0.1 2.9 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 6.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 3.3 GO:0051639 actin filament network formation(GO:0051639)
0.1 2.0 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 0.8 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.1 2.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 6.4 GO:0001885 endothelial cell development(GO:0001885)
0.1 4.3 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.1 0.2 GO:0048569 post-embryonic organ development(GO:0048569)
0.1 1.9 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 1.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 14.3 GO:0051260 protein homooligomerization(GO:0051260)
0.1 0.8 GO:1903729 regulation of plasma membrane organization(GO:1903729)
0.1 2.0 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 3.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.6 GO:0044209 AMP salvage(GO:0044209)
0.1 0.9 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.1 4.6 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 0.4 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 7.3 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 7.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 6.4 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.1 4.3 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 18.2 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 1.4 GO:0001706 endoderm formation(GO:0001706)
0.1 7.6 GO:0008016 regulation of heart contraction(GO:0008016)
0.1 5.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 19.4 GO:0006470 protein dephosphorylation(GO:0006470)
0.1 0.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 3.3 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 3.2 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.3 GO:0016233 telomere capping(GO:0016233)
0.0 2.9 GO:0043065 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 4.1 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.5 GO:0002263 cell activation involved in immune response(GO:0002263)
0.0 2.2 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 5.4 GO:0045944 positive regulation of transcription from RNA polymerase II promoter(GO:0045944)
0.0 1.7 GO:0006874 cellular calcium ion homeostasis(GO:0006874)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.5 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
2.0 8.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
1.1 16.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.9 4.6 GO:0005879 axonemal microtubule(GO:0005879)
0.8 8.0 GO:0045171 intercellular bridge(GO:0045171)
0.7 28.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.7 2.0 GO:1902560 GMP reductase complex(GO:1902560)
0.6 13.2 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.5 1.5 GO:0033268 node of Ranvier(GO:0033268)
0.4 3.0 GO:0043194 axon initial segment(GO:0043194)
0.4 2.5 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.4 27.8 GO:0043025 neuronal cell body(GO:0043025)
0.3 10.8 GO:0031594 neuromuscular junction(GO:0031594)
0.3 14.2 GO:0043204 perikaryon(GO:0043204)
0.3 15.6 GO:0030426 growth cone(GO:0030426)
0.3 3.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 16.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 2.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 1.0 GO:0070724 BMP receptor complex(GO:0070724)
0.2 2.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 6.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 1.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 2.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 20.3 GO:0030658 transport vesicle membrane(GO:0030658)
0.1 12.2 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 7.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 8.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 2.1 GO:0016363 nuclear matrix(GO:0016363)
0.1 4.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.3 GO:1990879 CST complex(GO:1990879)
0.1 4.3 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 2.0 GO:0005844 polysome(GO:0005844)
0.1 26.2 GO:0000139 Golgi membrane(GO:0000139)
0.1 13.0 GO:0030133 transport vesicle(GO:0030133)
0.1 0.8 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 3.6 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 22.5 GO:0043005 neuron projection(GO:0043005)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 8.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 5.2 GO:0005770 late endosome(GO:0005770)
0.0 2.7 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 12.2 GO:0005929 cilium(GO:0005929)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.5 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
2.4 14.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
2.3 11.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
2.0 8.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.9 11.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
1.5 4.6 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
1.5 10.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
1.3 8.1 GO:0031705 bombesin receptor binding(GO:0031705)
1.3 11.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.3 8.9 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
1.1 4.5 GO:0001607 neuromedin U receptor activity(GO:0001607)
1.1 10.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
1.0 13.4 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
1.0 21.8 GO:0019894 kinesin binding(GO:0019894)
0.9 7.0 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.8 16.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.7 12.7 GO:0008301 DNA binding, bending(GO:0008301)
0.7 2.0 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.6 2.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.6 4.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.5 16.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.5 3.9 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.5 13.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.5 1.9 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.5 3.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.5 6.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.4 15.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.4 7.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.4 8.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.3 2.4 GO:0030274 LIM domain binding(GO:0030274)
0.3 4.3 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.3 55.8 GO:0005516 calmodulin binding(GO:0005516)
0.2 1.4 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 7.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 8.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 14.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.2 2.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 4.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 1.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.2 6.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 2.9 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.2 2.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 5.6 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.2 3.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 3.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 1.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 1.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 3.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 1.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 3.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 7.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 31.8 GO:0042802 identical protein binding(GO:0042802)
0.1 0.6 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 8.5 GO:0051287 NAD binding(GO:0051287)
0.1 11.2 GO:0005179 hormone activity(GO:0005179)
0.1 3.5 GO:0035064 methylated histone binding(GO:0035064)
0.1 19.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 8.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 2.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 2.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.4 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.3 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 27.0 GO:0015631 tubulin binding(GO:0015631)
0.1 0.9 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 6.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.4 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 6.0 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 73.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 4.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 8.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.6 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 1.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 2.0 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 1.3 GO:0008083 growth factor activity(GO:0008083)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 28.7 ST G ALPHA I PATHWAY G alpha i Pathway
0.6 10.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.5 11.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.3 6.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.3 3.9 PID S1P S1P1 PATHWAY S1P1 pathway
0.3 14.2 PID NOTCH PATHWAY Notch signaling pathway
0.3 2.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.3 15.6 PID AP1 PATHWAY AP-1 transcription factor network
0.2 12.7 PID CMYB PATHWAY C-MYB transcription factor network
0.1 4.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 4.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 0.7 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 3.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 2.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 2.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.3 PID E2F PATHWAY E2F transcription factor network
0.0 0.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.5 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 21.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.1 17.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.7 11.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.7 29.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.6 8.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.5 11.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 14.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.4 6.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.4 3.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 3.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 3.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 4.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 2.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 13.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 2.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 2.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 2.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 5.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 11.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.7 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 2.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 2.2 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 3.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.1 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity